Bus tickets Rome to Brussels from £50

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Compare all timetables for the bus from Rome to Brussels

Here is a selection of the cheapest bus trips from the schedule from Rome to Brussels from various bus operators like FlixBus for the next days.

today
£58
tomorrow
Thursday
£56
Friday
Saturday
£64
Sunday
Monday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 34h 20m 21:00 Rome Tiburtina Bus Station 07:20 Brussels Midi Bus Station  Economy £58
FlixBus 30h 10m 17:00 Rome Tiburtina Bus Station 23:10 Brussels North Station  Economy £58
FlixBus 33h 30m 22:45 Rome Tiburtina Bus Station 08:15 Brussels Midi Bus Station  Economy £59
FlixBus 29h 40m 20:00 Rome Tiburtina Bus Station 01:40 Brussels Midi Bus Station  Economy £61
FlixBus 30h 20m 13:05 Rome Anagnina Bus Station 19:25 Brussels North Station  Economy £61

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 28h 50m 13:05 Rome Anagnina Bus Station 17:55 Brussels Midi Bus Station  Economy £56
FlixBus 23h 5m 09:35 Rome Tiburtina Bus Station 08:40 Brussels North Station  Economy £57
FlixBus 28h 35m 07:45 Rome Tiburtina Bus Station 12:20 Brussels Midi Bus Station  Economy £57
FlixBus 31h 0m 08:50 Rome Tiburtina Bus Station 15:50 Brussels Midi Bus Station  Economy £57
FlixBus 27h 40m 13:05 Rome Anagnina Bus Station 16:45 Brussels North Station  Economy £57

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 27h 55m 08:50 Rome Tiburtina Bus Station 12:45 Brussels Midi Bus Station  Economy £64
FlixBus 31h 0m 08:50 Rome Tiburtina Bus Station 15:50 Brussels Midi Bus Station  Economy £64
FlixBus 22h 30m 10:10 Rome Tiburtina Bus Station 08:40 Brussels North Station  Economy £64
FlixBus 24h 25m 11:10 Rome Anagnina Bus Station 11:35 Brussels North Station  Economy £65
FlixBus 26h 50m 00:10 Rome Tiburtina Bus Station 03:00 Brussels North Station  Economy £66
  • Did you know that if you travel from Rome to Brussels via Parma, you can save more than £6? You can find the corresponding connections below.
    • Distribusion
      27h 45m
      0
      13:00
      Rome
      Tiburtina Bus Station
      19:05
      Parma
      Via Villa Sant'Angelo Coach Station
      0
      Distribusion
      Premium Economy
      £10
      • Waiting Time 0h 40m
    • FlixBus
      21h 0m
      0
      19:45
      Parma
      Via Villa Sant'Angelo Coach Station
      16:45
      Brussels
      North Station
      0
      FlixBus
      Economy
      £48
    Travel time is 5h 15m longer, but you will save £6

Best Price Offer: The price for the cheapest coach from Rome to Brussels is £50 on 11/02/2026. Flexible travellers save on ticket prices.


Frequency of bus connections between Rome and Brussels

See here how frequent the connections between Rome and Brussels are, during different times and days of the week.
Thursday is the busiest day, with more than 18 daily coaches from Rome to Brussels. Tuesday has instead the fewest connections, with only 6 daily coaches between Rome and Brussels.
The busiest time of the day is the Evening, with 14 coaches from Rome to Brussels, while Night sees the fewest connections between Rome and Brussels, with 4 offers.

Facts about coaches from Rome to Brussels

Compare all providers like FlixBus that travel 14 times every day by bus from Rome to Brussels in one click! Book your bus ticket from Rome to Brussels starting from £50!

Cheapest Bus £50
Fastest Bus 22h 30m
Earliest Coach 12:10
Latest Coach 23:35
Daily Bus Connections 14 Ø
Distance 1,173.4 km
Coach Companies FlixBus

Cheapest coach connections from Rome to Brussels

Every day, 14 buses from 1 coach companies leave Rome for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 20/01/2026 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 19/01
Tuesday 20/01
£57
Wednesday 21/01
Thursday 22/01
£56
Friday 23/01
Saturday 24/01
£64
Sunday 25/01
Monday 26/01
Tuesday 27/01
£62
Wednesday 28/01
Thursday 29/01
Friday 30/01
Saturday 31/01
Sunday 01/02
Monday 02/02
Tuesday 03/02
Wednesday 04/02
Thursday 05/02
Friday 06/02
Saturday 07/02
£62
Sunday 08/02
£63
Monday 09/02
Tuesday 10/02
£58
Wednesday 11/02
£50
Thursday 12/02
Friday 13/02
Saturday 14/02
Sunday 15/02

The cheapest time to travel from Rome to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Brussels, for the next 30 days.
With a price starting from £56, Thursday is the cheapest day for a coach from Rome to Brussels. Saturday instead is the most expensive day with prices starting from £62.
Night is the cheapest day time for bus tickets from Rome to Brussels, with £50. Evening is the most expensive time of the day with prices starting from £58.

How to save money travelling from Rome to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Rome to Brussels are also emptier.

All bus stations and stops in Rome and Brussels

The map below shows you where to find all the bus stations in Rome and Brussels.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Rome to Brussels? Compare all modes of transports from Rome to Brussels.

Service and Comfort on the bus from Rome to Brussels

Want to know which seat classes are available on the coaches from Rome to Brussels? Or which bus companies serve the route Rome to Brussels? Below you will find answers to your questions.

FAQs about the Rome to Brussels bus

How much does a Rome - Brussels coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Rome - Brussels bus trip is available from £50 and takes 28h 50m. Compare offers and save money!

How much could I save by comparing buses from Rome to Brussels?

The connection Rome to Brussels is offered by 1 companies with ticket prices ranging from £50 to £93. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Rome - Brussels route on average every day?

Each day, the bus route from Rome to Brussels is offered by roughly 14 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Brussels from Rome take?

The quickest coach from Rome to Brussels is provided by FlixBus and takes 22h 30m. Coach tickets for this connection cost £64. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Rome to Brussels?

The earliest bus to Brussels departs from Rome at 12:10. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Rome to Brussels?

The latest bus to Brussels departs from Rome at 23:35. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Rome - Brussels route?

Passengers looking to travel from Rome to Brussels can travel with FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Rome and Brussels?

You can check all the direct connections between Rome and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the bus to Brussels from Rome?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Rome Brussels bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Brussels on your planned travel date.

How does CheckMyBus find the best bus deals from Rome to Brussels?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 14 daily trips between Rome and Brussels. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Brussels?

Prices and availability for 14 trips between Rome and Brussels change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Brussels

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Rome and to Brussels

Here’s an overview of the most popular bus routes to Rome and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus from Messina to Rome Bus from Messina to Rome
Coach from Sibari to Rome Coach from Sibari to Rome
Coach to Rome from Foggia Coach to Rome from Foggia
Buses Matera to Rome Buses Matera to Rome
Bus to Brussels from Paris Bus to Brussels from Paris
Coach Bruges (BE) to Brussels Coach Bruges (BE) to Brussels
Coach Cologne to Brussels Coach Cologne to Brussels
Buses Ghent to Brussels Buses Ghent to Brussels
Popular Airport Transfers to Rome and to Brussels
CheckMyBus › Coaches in Italy › Coach to Rome › Coach to Brussels

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