What is the best way to travel from Rome to Brussels?
Looking for a trip? Check and compare all the available Flights and Buses to Brussels from Rome. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Brussels from Rome?
You can reach Brussels with just £21 by taking a Flight from Skyscanner, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Ryanair2h 20m006:20Rome Fiumicino AirportRome Fiumicino Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 22/03/2026 06:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 22/03/2026 08:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 2h 20m
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EasyJet Airline2h 20m006:20Rome Fiumicino AirportRome Fiumicino Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 22/03/2026 06:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 22/03/2026 08:40:00. 50 Economy ticket for £41 per person are available. Travel duration is 2h 20m
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Wizz Air22h 40m020:40Rome Fiumicino AirportRome Fiumicino Airport19:20Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 22/03/2026 20:40:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 23/03/2026 19:20:00. 50 Economy ticket for £110 per person are available. Travel duration is 22h 40m
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Wizz Air7h 15m008:40Rome Fiumicino AirportRome Fiumicino Airport15:55Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 22/03/2026 08:40:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 22/03/2026 15:55:00. 50 Economy ticket for £111 per person are available. Travel duration is 7h 15m
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Wizz Air23h 35m008:45Rome Fiumicino AirportRome Fiumicino Airport08:20Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 22/03/2026 08:45:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 23/03/2026 08:20:00. 50 Economy ticket for £111 per person are available. Travel duration is 23h 35m
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ITA Airways23h 55m009:00Rome Fiumicino AirportRome Fiumicino Airport08:55Brussels AirportBrussels Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 22/03/2026 09:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 23/03/2026 08:55:00. 50 Economy ticket for £145 per person are available. Travel duration is 23h 55m
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FlixBus22h 30m010:10RomeTiburtina Bus Station08:40BrusselsNorth Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 22/03/2026 10:10:00 to North Station, Brussels (Belgium) arriving at 23/03/2026 08:40:00. 50 Economy ticket for £59 per person are available. Travel duration is 22h 30m
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FlixBus28h 20m022:45RomeTiburtina Bus Station03:05BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 22/03/2026 22:45:00 to Midi Bus Station, Brussels (Belgium) arriving at 24/03/2026 03:05:00. 50 Economy ticket for £61 per person are available. Travel duration is 28h 20m
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FlixBus28h 35m007:45RomeTiburtina Bus Station12:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 22/03/2026 07:45:00 to Midi Bus Station, Brussels (Belgium) arriving at 23/03/2026 12:20:00. 50 Economy ticket for £65 per person are available. Travel duration is 28h 35m
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FlixBus24h 0m008:30RomeTiburtina Bus Station08:30BrusselsNorth Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 22/03/2026 08:30:00 to North Station, Brussels (Belgium) arriving at 23/03/2026 08:30:00. 50 Economy ticket for £66 per person are available. Travel duration is 24h 0m
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FlixBus23h 25m012:10RomeTiburtina Bus Station11:35BrusselsNorth Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 22/03/2026 12:10:00 to North Station, Brussels (Belgium) arriving at 23/03/2026 11:35:00. 50 Economy ticket for £66 per person are available. Travel duration is 23h 25m
Cheapest Flights Sunday
Cheapest Buses Sunday
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Skyscanner2h 10m006:20Rome Ciampino AirportRome Ciampino Airport08:30Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 23/03/2026 06:20:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 23/03/2026 08:30:00. 50 Economy ticket for £39 per person are available. Travel duration is 2h 10m
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South African Express Airways5h 10m010:20Rome Fiumicino AirportRome Fiumicino Airport15:30Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from South African Express Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 23/03/2026 10:20:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 23/03/2026 15:30:00. 50 Economy ticket for £59 per person are available. Travel duration is 5h 10m
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Ryanair9h 40m022:45Rome Fiumicino AirportRome Fiumicino Airport08:25Brussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 23/03/2026 22:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 24/03/2026 08:25:00. 50 Economy ticket for £61 per person are available. Travel duration is 9h 40m
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ITA Airways6h 0m009:30Rome Fiumicino AirportRome Fiumicino Airport15:30Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 23/03/2026 09:30:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 23/03/2026 15:30:00. 50 Economy ticket for £68 per person are available. Travel duration is 6h 0m
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Wizz Air23h 35m008:45Rome Fiumicino AirportRome Fiumicino Airport08:20Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 23/03/2026 08:45:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 24/03/2026 08:20:00. 50 Economy ticket for £79 per person are available. Travel duration is 23h 35m
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ITA Airways13h 35m019:00Rome Fiumicino AirportRome Fiumicino Airport08:35Brussels AirportBrussels Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 23/03/2026 19:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 24/03/2026 08:35:00. 50 Economy ticket for £90 per person are available. Travel duration is 13h 35m
Cheapest Flights Monday
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FlixBus37h 15m004:40Rome Ciampino AirportRome Ciampino Airport17:55BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 24/03/2026 04:40:00 to Midi Bus Station, Brussels (Belgium) arriving at 25/03/2026 17:55:00. 50 Economy ticket for £53 per person are available. Travel duration is 37h 15m
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FlixBus34h 20m021:00RomeTiburtina Bus Station07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 24/03/2026 21:00:00 to Midi Bus Station, Brussels (Belgium) arriving at 26/03/2026 07:20:00. 50 Economy ticket for £58 per person are available. Travel duration is 34h 20m
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FlixBus33h 30m022:45RomeTiburtina Bus Station08:15BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 24/03/2026 22:45:00 to Midi Bus Station, Brussels (Belgium) arriving at 26/03/2026 08:15:00. 50 Economy ticket for £59 per person are available. Travel duration is 33h 30m
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FlixBus31h 50m016:35RomeTiburtina Bus Station00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 24/03/2026 16:35:00 to North Station, Brussels (Belgium) arriving at 26/03/2026 00:25:00. 50 Economy ticket for £60 per person are available. Travel duration is 31h 50m
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FlixBus32h 40m012:10RomeTiburtina Bus Station20:50BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 24/03/2026 12:10:00 to Midi Bus Station, Brussels (Belgium) arriving at 25/03/2026 20:50:00. 50 Economy ticket for £63 per person are available. Travel duration is 32h 40m
Cheapest Buses Tuesday
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Skyscanner2h 10m006:00Rome Ciampino AirportRome Ciampino Airport08:10Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 26/03/2026 06:00:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 26/03/2026 08:10:00. 50 Economy ticket for £21 per person are available. Travel duration is 2h 10m
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Skyscanner2h 10m008:45Rome Fiumicino AirportRome Fiumicino Airport10:55Brussels AirportBrussels Airport0EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 26/03/2026 08:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 26/03/2026 10:55:00. 50 Economy ticket for £42 per person are available. Travel duration is 2h 10m
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Skyscanner2h 10m012:55Rome Ciampino AirportRome Ciampino Airport15:05Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 26/03/2026 12:55:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 26/03/2026 15:05:00. 50 Economy ticket for £43 per person are available. Travel duration is 2h 10m
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EasyJet Airline2h 20m006:20Rome Fiumicino AirportRome Fiumicino Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 26/03/2026 06:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 26/03/2026 08:40:00. 50 Economy ticket for £44 per person are available. Travel duration is 2h 20m
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Wizz Air18h 20m021:35Rome Fiumicino AirportRome Fiumicino Airport15:55Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 26/03/2026 21:35:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 27/03/2026 15:55:00. 50 Economy ticket for £62 per person are available. Travel duration is 18h 20m
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South African Express Airways5h 30m016:20Rome Fiumicino AirportRome Fiumicino Airport21:50Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from South African Express Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 26/03/2026 16:20:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 26/03/2026 21:50:00. 50 Economy ticket for £64 per person are available. Travel duration is 5h 30m
Cheapest Flights Thursday
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Skyscanner2h 10m006:20Rome Ciampino AirportRome Ciampino Airport08:30Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 27/03/2026 06:20:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 27/03/2026 08:30:00. 50 Economy ticket for £21 per person are available. Travel duration is 2h 10m
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Skyscanner2h 10m005:45Rome Fiumicino AirportRome Fiumicino Airport07:55Brussels AirportBrussels Airport0EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 27/03/2026 05:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 27/03/2026 07:55:00. 50 Economy ticket for £32 per person are available. Travel duration is 2h 10m
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LC Perú11h 5m021:45Rome Fiumicino AirportRome Fiumicino Airport08:50Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from LC Perú goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 27/03/2026 21:45:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 28/03/2026 08:50:00. 50 Economy ticket for £42 per person are available. Travel duration is 11h 5m
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EasyJet Airline2h 20m006:20Rome Fiumicino AirportRome Fiumicino Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 27/03/2026 06:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 27/03/2026 08:40:00. 50 Economy ticket for £49 per person are available. Travel duration is 2h 20m
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Wizz Air23h 25m016:30Rome Fiumicino AirportRome Fiumicino Airport15:55Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 27/03/2026 16:30:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 28/03/2026 15:55:00. 50 Economy ticket for £54 per person are available. Travel duration is 23h 25m
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Ryanair2h 10m020:40Rome Ciampino AirportRome Ciampino Airport22:50Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 27/03/2026 20:40:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 27/03/2026 22:50:00. 50 Economy ticket for £58 per person are available. Travel duration is 2h 10m
Cheapest Flights Friday
What are the fastest trips from Rome to Brussels?
You can get to Brussels from Rome in just 2h 10m with a Flight from Skyscanner. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Ryanair2h 20m006:20Rome Fiumicino AirportRome Fiumicino Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 22/03/2026 06:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 22/03/2026 08:40:00. 50 Economy ticket for £34 per person are available. Travel duration is 2h 20m
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EasyJet Airline2h 20m006:20Rome Fiumicino AirportRome Fiumicino Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 22/03/2026 06:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 22/03/2026 08:40:00. 50 Economy ticket for £41 per person are available. Travel duration is 2h 20m
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Wizz Air7h 15m008:40Rome Fiumicino AirportRome Fiumicino Airport15:55Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 22/03/2026 08:40:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 22/03/2026 15:55:00. 50 Economy ticket for £111 per person are available. Travel duration is 7h 15m
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Wizz Air11h 25m021:30Rome Fiumicino AirportRome Fiumicino Airport08:55Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 22/03/2026 21:30:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 23/03/2026 08:55:00. 50 Economy ticket for £174 per person are available. Travel duration is 11h 25m
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Vueling Airlines12h 25m020:30Rome Fiumicino AirportRome Fiumicino Airport08:55Brussels AirportBrussels Airport0EconomyA Flight from Vueling Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 22/03/2026 20:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 23/03/2026 08:55:00. 50 Economy ticket for £174 per person are available. Travel duration is 12h 25m
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Wizz Air18h 20m021:35Rome Fiumicino AirportRome Fiumicino Airport15:55Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Wizz Air goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 22/03/2026 21:35:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 23/03/2026 15:55:00. 50 Economy ticket for £176 per person are available. Travel duration is 18h 20m
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FlixBus22h 30m010:10RomeTiburtina Bus Station08:40BrusselsNorth Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 22/03/2026 10:10:00 to North Station, Brussels (Belgium) arriving at 23/03/2026 08:40:00. 50 Economy ticket for £59 per person are available. Travel duration is 22h 30m
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FlixBus23h 25m012:10RomeTiburtina Bus Station11:35BrusselsNorth Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 22/03/2026 12:10:00 to North Station, Brussels (Belgium) arriving at 23/03/2026 11:35:00. 50 Economy ticket for £66 per person are available. Travel duration is 23h 25m
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FlixBus24h 0m008:30RomeTiburtina Bus Station08:30BrusselsNorth Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 22/03/2026 08:30:00 to North Station, Brussels (Belgium) arriving at 23/03/2026 08:30:00. 50 Economy ticket for £66 per person are available. Travel duration is 24h 0m
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FlixBus28h 20m022:45RomeTiburtina Bus Station03:05BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 22/03/2026 22:45:00 to Midi Bus Station, Brussels (Belgium) arriving at 24/03/2026 03:05:00. 50 Economy ticket for £61 per person are available. Travel duration is 28h 20m
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FlixBus28h 35m007:45RomeTiburtina Bus Station12:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 22/03/2026 07:45:00 to Midi Bus Station, Brussels (Belgium) arriving at 23/03/2026 12:20:00. 50 Economy ticket for £65 per person are available. Travel duration is 28h 35m
Fastest Flights Sunday
Fastest Buses Sunday
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Skyscanner2h 10m006:20Rome Ciampino AirportRome Ciampino Airport08:30Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 23/03/2026 06:20:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 23/03/2026 08:30:00. 50 Economy ticket for £39 per person are available. Travel duration is 2h 10m
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Smartwings4h 45m014:00Rome Fiumicino AirportRome Fiumicino Airport18:45Brussels AirportBrussels Airport0EconomyA Flight from Smartwings goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 23/03/2026 14:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 23/03/2026 18:45:00. 50 Economy ticket for £103 per person are available. Travel duration is 4h 45m
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South African Express Airways5h 10m010:20Rome Fiumicino AirportRome Fiumicino Airport15:30Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from South African Express Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 23/03/2026 10:20:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 23/03/2026 15:30:00. 50 Economy ticket for £59 per person are available. Travel duration is 5h 10m
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ITA Airways6h 0m009:30Rome Fiumicino AirportRome Fiumicino Airport15:30Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 23/03/2026 09:30:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 23/03/2026 15:30:00. 50 Economy ticket for £68 per person are available. Travel duration is 6h 0m
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Skyscanner6h 0m009:30Rome Fiumicino AirportRome Fiumicino Airport15:30Brussels AirportBrussels Airport0EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 23/03/2026 09:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 23/03/2026 15:30:00. 50 Economy ticket for £93 per person are available. Travel duration is 6h 0m
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Ryanair9h 40m022:45Rome Fiumicino AirportRome Fiumicino Airport08:25Brussels AirportBrussels Airport0EconomyA Flight from Ryanair goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 23/03/2026 22:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 24/03/2026 08:25:00. 50 Economy ticket for £61 per person are available. Travel duration is 9h 40m
Fastest Flights Monday
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FlixBus31h 50m016:35RomeTiburtina Bus Station00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 24/03/2026 16:35:00 to North Station, Brussels (Belgium) arriving at 26/03/2026 00:25:00. 50 Economy ticket for £60 per person are available. Travel duration is 31h 50m
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FlixBus32h 40m012:10RomeTiburtina Bus Station20:50BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 24/03/2026 12:10:00 to Midi Bus Station, Brussels (Belgium) arriving at 25/03/2026 20:50:00. 50 Economy ticket for £63 per person are available. Travel duration is 32h 40m
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FlixBus33h 30m022:45RomeTiburtina Bus Station08:15BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 24/03/2026 22:45:00 to Midi Bus Station, Brussels (Belgium) arriving at 26/03/2026 08:15:00. 50 Economy ticket for £59 per person are available. Travel duration is 33h 30m
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FlixBus34h 20m021:00RomeTiburtina Bus Station07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 24/03/2026 21:00:00 to Midi Bus Station, Brussels (Belgium) arriving at 26/03/2026 07:20:00. 50 Economy ticket for £58 per person are available. Travel duration is 34h 20m
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FlixBus37h 15m004:40Rome Ciampino AirportRome Ciampino Airport17:55BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 24/03/2026 04:40:00 to Midi Bus Station, Brussels (Belgium) arriving at 25/03/2026 17:55:00. 50 Economy ticket for £53 per person are available. Travel duration is 37h 15m
Fastest Buses Tuesday
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Skyscanner2h 10m006:00Rome Ciampino AirportRome Ciampino Airport08:10Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 26/03/2026 06:00:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 26/03/2026 08:10:00. 50 Economy ticket for £21 per person are available. Travel duration is 2h 10m
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Skyscanner2h 10m012:55Rome Ciampino AirportRome Ciampino Airport15:05Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 26/03/2026 12:55:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 26/03/2026 15:05:00. 50 Economy ticket for £43 per person are available. Travel duration is 2h 10m
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Skyscanner2h 10m008:45Rome Fiumicino AirportRome Fiumicino Airport10:55Brussels AirportBrussels Airport0EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 26/03/2026 08:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 26/03/2026 10:55:00. 50 Economy ticket for £42 per person are available. Travel duration is 2h 10m
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Brussels Airlines2h 15m010:00Rome Fiumicino AirportRome Fiumicino Airport12:15Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 26/03/2026 10:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 26/03/2026 12:15:00. 50 Economy ticket for £72 per person are available. Travel duration is 2h 15m
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EasyJet Airline2h 20m006:20Rome Fiumicino AirportRome Fiumicino Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 26/03/2026 06:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 26/03/2026 08:40:00. 50 Economy ticket for £44 per person are available. Travel duration is 2h 20m
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South African Express Airways5h 0m017:50Rome Fiumicino AirportRome Fiumicino Airport22:50Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from South African Express Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 26/03/2026 17:50:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 26/03/2026 22:50:00. 50 Economy ticket for £71 per person are available. Travel duration is 5h 0m
Fastest Flights Thursday
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Skyscanner2h 10m006:20Rome Ciampino AirportRome Ciampino Airport08:30Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Skyscanner goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 27/03/2026 06:20:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 27/03/2026 08:30:00. 50 Economy ticket for £21 per person are available. Travel duration is 2h 10m
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Ryanair2h 10m020:40Rome Ciampino AirportRome Ciampino Airport22:50Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Ryanair goes from Rome Ciampino Airport, Rome Ciampino Airport (Italy) at 27/03/2026 20:40:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 27/03/2026 22:50:00. 50 Economy ticket for £58 per person are available. Travel duration is 2h 10m
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Skyscanner2h 10m005:45Rome Fiumicino AirportRome Fiumicino Airport07:55Brussels AirportBrussels Airport0EconomyA Flight from Skyscanner goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 27/03/2026 05:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 27/03/2026 07:55:00. 50 Economy ticket for £32 per person are available. Travel duration is 2h 10m
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Brussels Airlines2h 15m010:00Rome Fiumicino AirportRome Fiumicino Airport12:15Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 27/03/2026 10:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 27/03/2026 12:15:00. 50 Economy ticket for £90 per person are available. Travel duration is 2h 15m
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EasyJet Airline2h 20m006:20Rome Fiumicino AirportRome Fiumicino Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 27/03/2026 06:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 27/03/2026 08:40:00. 50 Economy ticket for £49 per person are available. Travel duration is 2h 20m
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ITA Airways4h 15m018:35Rome Fiumicino AirportRome Fiumicino Airport22:50Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from ITA Airways goes from Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) at 27/03/2026 18:35:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 27/03/2026 22:50:00. 50 Economy ticket for £64 per person are available. Travel duration is 4h 15m
Fastest Flights Friday
Here you will find all operators and timetables for a
Bus from Rome to Brussels
What are the most popular stations in Rome and Brussels?
In Rome, you will usually depart from Termini Bus Station, Termini Central Station or Ostiense Train Station, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brussels from Rome? With 10 connections between 1 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Rome and Brussels, you can pay as low as £21 with a Flight from Skyscanner.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Brussels in just 2h 10m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Rome and Brussels are FlixBus, Wizz Air and Skyscanner, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Rome and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Settebagni or to Saint-Gilles, and look at flights from Rome Ciampino Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Rome to Brussels?
The most popular companies between Rome and Brussels, are FlixBus, Wizz Air and Skyscanner. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: Wizz Air, Skyscanner, ITA Airways and 9 more.
All you need to know when you travel from Rome to Brussels
Check all information on comfort and services on all modes of transports from Rome to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Rome to Brussels
How can I reach Brussels from Rome?
Every day, there are on average 10 connections between Flight and Bus, with which you can get to Brussels from Rome.
How far is Brussels from Rome?
The distance between Rome and Brussels is 1,173.4 km.
What is the most ecofriendly mode of transport between Rome and Brussels?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 32 kgs of CO2, a train 41 kgs, a car 199 kgs, and a flight 289 kgs.
What is the cheapest mode of transport from Rome to Brussels?
You can get to Brussels with just £21 by taking a Flight from Skyscanner.
What is the fastest way to get from Rome to Brussels?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 2h 10m with a Flight from Skyscanner.
More routes to Rome and to Brussels
Looking for more options? Here you can see the most popular routes to Rome and to Brussels. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Rome
- Avellino to Rome
- Bari to Rome
- Battipaglia to Rome
- Caserta to Rome
- Catanzaro to Rome
- Chieti to Rome
- Civitanova to Rome
- Grottaminarda to Rome
- L'Aquila to Rome
- Lamezia Terme to Rome
- Lecce to Rome
- Marseille to Rome
- Milan to Rome
- Mosciano Sant'Angelo to Rome
- Naples to Rome
- Nocera Inferiore to Rome
- Perugia to Rome
- Pescara to Rome
- Potenza to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Venice to Rome
- Trips to Brussels
- Amiens to Brussels
- Amsterdam to Brussels
- Barcelona to Brussels
- Basel to Brussels
- Birmingham to Brussels
- Bordeaux to Brussels
- Bratislava to Brussels
- Brussels Airport to Brussels
- Brussels South Charleroi Airport to Brussels
- Cologne/Bonn Airport to Brussels
- Glasgow to Brussels
- Lisbon to Brussels
- London to Brussels
- Lyon to Brussels
- Malaga to Brussels
- Milan to Brussels
- Newcastle upon Tyne to Brussels
- Nottingham to Brussels
- Paris to Brussels
- Salzburg to Brussels
- The Hague to Brussels
- Toulouse to Brussels
- Vienna to Brussels
- Zurich to Brussels
