Bus tickets Prague to Brussels from £20

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Compare all timetables for the bus from Prague to Brussels

Here is a selection of the cheapest bus trips from the schedule from Prague to Brussels from various bus operators like FlixBus or European Sleeper for the next days.

today
£37
tomorrow
£32
Sunday
£42
Monday
£25
Tuesday
£20
Wednesday
£20
Thursday
£28

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 16h 15m 22:25 Prague Hradčanská 14:40 Brussels North Station  Economy £37
FlixBus 15h 45m 18:30 Prague Wilsonova Coach Station 10:15 Brussels North Station  Economy £38
FlixBus 18h 5m 23:50 Prague Wilsonova Coach Station 17:55 Brussels North Station  Economy £38
FlixBus 16h 50m 21:50 Prague Na Knížecí Station 14:40 Brussels North Station  Economy £38
FlixBus 14h 45m 19:30 Prague ÚAN Florenc 10:15 Brussels North Station  Economy £38
  • Did you know that if you travel from Prague to Brussels via Maastricht, you can save more than £5? You can find the corresponding connections below.
    • FlixBus
      14h 49m
      0
      09:10
      Prague
      Na Knížecí Station
      22:05
      Maastricht
      Meerssenerweg
      0
      FlixBus
      Economy
      £25
      • Waiting Time 0h 10m
    • FlixBus
      1h 44m
      0
      22:15
      Maastricht
      Meerssenerweg
      23:59
      Brussels
      North Station
      0
      FlixBus
      Economy
      £7
    Travel time is 0h 4m longer, but you will save £5

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 49m 09:10 Prague Na Knížecí Station 23:59 Brussels North Station  Economy £32
FlixBus 16h 35m 09:10 Prague Na Knížecí Station 01:45 Brussels Midi Bus Station  Economy £32
FlixBus 15h 35m 23:05 Prague ÚAN Florenc 14:40 Brussels North Station  Economy £32
FlixBus 15h 15m 10:30 Prague ÚAN Florenc 01:45 Brussels Midi Bus Station  Economy £32
FlixBus 18h 25m 18:00 Prague ÚAN Florenc 12:25 Brussels Heysel  Economy £32

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 19h 30m 22:25 Prague Zličín 17:55 Brussels North Station  Economy £42
FlixBus 18h 5m 22:25 Prague Hradčanská 16:30 Brussels North Station  Economy £43
FlixBus 17h 40m 04:00 Prague Wilsonova Coach Station 21:40 Brussels North Station  Economy £45
European Sleeper 15h 27m 18:00 Prague Wilsonova Coach Station 09:27 Brussels Midi Bus Station  Economy £263
  • Did you know that if you travel from Prague to Brussels via Maastricht, you can save more than £14? You can find the corresponding connections below.
    • FlixBus
      16h 50m
      0
      21:50
      Prague
      Na Knížecí Station
      11:10
      Maastricht
      Meerssenerweg
      0
      FlixBus
      Economy
      £22
      • Waiting Time 1h 20m
    • FlixBus
      2h 10m
      0
      12:30
      Maastricht
      Meerssenerweg
      14:40
      Brussels
      North Station
      0
      FlixBus
      Economy
      £6
    Travel time is 1h 23m longer, but you will save £14

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 5m 23:50 Prague Wilsonova Coach Station 17:55 Brussels North Station  Economy £25
FlixBus 17h 0m 01:45 Prague Wilsonova Coach Station 18:45 Brussels North Station  Economy £26
FlixBus 17h 40m 04:00 Prague Wilsonova Coach Station 21:40 Brussels North Station  Economy £26
FlixBus 17h 40m 13:05 Prague Wilsonova Coach Station 06:45 Brussels North Station  Economy £26
FlixBus 16h 0m 17:30 Prague Wilsonova Coach Station 09:30 Brussels North Station  Economy £26
  • Did you know that if you travel from Prague to Brussels via Maastricht, you can save more than £3? You can find the corresponding connections below.
    • FlixBus
      15h 20m
      0
      09:10
      Prague
      Na Knížecí Station
      22:35
      Maastricht
      Meerssenerweg
      0
      FlixBus
      Economy
      £16
      • Waiting Time 0h 10m
    • FlixBus
      1h 45m
      0
      22:45
      Maastricht
      Meerssenerweg
      00:30
      Brussels
      North Station
      0
      FlixBus
      Economy
      £6
    Travel Time is 0h 40m shorter, and you will save £3

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 17h 0m 01:45 Prague Wilsonova Coach Station 18:45 Brussels North Station  Economy £20
FlixBus 17h 40m 13:05 Prague Wilsonova Coach Station 06:45 Brussels North Station  Economy £20
FlixBus 15h 20m 09:10 Prague Na Knížecí Station 00:30 Brussels North Station  Economy £20
European Sleeper 16h 30m 18:00 Prague Wilsonova Coach Station 10:30 Brussels Midi Bus Station  Economy £180

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 17h 0m 01:45 Prague Wilsonova Coach Station 18:45 Brussels North Station  Economy £20
FlixBus 18h 5m 23:50 Prague Wilsonova Coach Station 17:55 Brussels North Station  Economy £20
FlixBus 16h 5m 21:50 Prague Na Knížecí Station 13:55 Brussels Midi Bus Station  Economy £20
FlixBus 15h 35m 23:05 Prague ÚAN Florenc 14:40 Brussels North Station  Economy £20
FlixBus 19h 25m 18:30 Prague Wilsonova Coach Station 13:55 Brussels Midi Bus Station  Economy £20

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 17h 0m 01:45 Prague Wilsonova Coach Station 18:45 Brussels North Station  Economy £28
FlixBus 17h 40m 04:00 Prague Wilsonova Coach Station 21:40 Brussels North Station  Economy £28
FlixBus 16h 0m 17:30 Prague Wilsonova Coach Station 09:30 Brussels North Station  Economy £28
European Sleeper 15h 27m 18:00 Prague Wilsonova Coach Station 09:27 Brussels Midi Bus Station  Economy £263
  • Did you know that if you travel from Prague to Brussels via Maastricht, you can save more than £7? You can find the corresponding connections below.
    • FlixBus
      16h 50m
      0
      21:50
      Prague
      Na Knížecí Station
      11:10
      Maastricht
      Meerssenerweg
      0
      FlixBus
      Economy
      £15
      • Waiting Time 1h 20m
    • FlixBus
      2h 10m
      0
      12:30
      Maastricht
      Meerssenerweg
      14:40
      Brussels
      North Station
      0
      FlixBus
      Economy
      £6
    Travel time is 1h 23m longer, but you will save £7

Best Price Offer: The price for the cheapest coach from Prague to Brussels is £20 on 22/09/2026. Flexible travellers save on ticket prices.


Frequency of bus connections between Prague and Brussels

See here how frequent the connections between Prague and Brussels are, during different times and days of the week.
Wednesday is the busiest day, with more than 39 daily coaches from Prague to Brussels. Tuesday has instead the fewest connections, with only 33 daily coaches between Prague and Brussels.
The busiest time of the day is the Evening, with 102 coaches from Prague to Brussels, while Night sees the fewest connections between Prague and Brussels, with 28 offers.

Facts about coaches from Prague to Brussels

Compare all providers like FlixBus and European Sleeper that travel 37 times every day by bus from Prague to Brussels in one click! Book your bus ticket from Prague to Brussels starting from £20!

Cheapest Bus £20
Fastest Bus 13h 29m
Earliest Coach 01:45
Latest Coach 23:50
Daily Bus Connections 37 Ø
Distance 718.5 km
Coach Companies FlixBus and European Sleeper

Cheapest coach connections from Prague to Brussels

Every day, 37 buses from 2 coach companies leave Prague for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 18/09/2026 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 14/09
Tuesday 15/09
Wednesday 16/09
Thursday 17/09
Friday 18/09
£37
Saturday 19/09
£32
Sunday 20/09
£42
Monday 21/09
£25
Tuesday 22/09
£20
Wednesday 23/09
£20
Thursday 24/09
£28
Friday 25/09
£35
Saturday 26/09
£32
Sunday 27/09
£45
Monday 28/09
£38
Tuesday 29/09
£33
Wednesday 30/09
£31
Thursday 01/10
£42
Friday 02/10
£46
Saturday 03/10
£43
Sunday 04/10
£46
Monday 05/10
£39
Tuesday 06/10
£34
Wednesday 07/10
£34
Thursday 08/10
£36
Friday 09/10
£42
Saturday 10/10
£42
Sunday 11/10

The cheapest time to travel from Prague to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Brussels, for the next 30 days.
With a price starting from £20, Tuesday is the cheapest day for a coach from Prague to Brussels. Sunday instead is the most expensive day with prices starting from £42.
Evening is the cheapest day time for bus tickets from Prague to Brussels, with £20. Morning is the most expensive time of the day with prices starting from £20.

How to save money travelling from Prague to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Prague to Brussels are also emptier.

All bus stations and stops in Prague and Brussels

The map below shows you where to find all the bus stations in Prague and Brussels.

Service and Comfort on the bus from Prague to Brussels

Want to know which seat classes are available on the coaches from Prague to Brussels? Or which bus companies serve the route Prague to Brussels? Below you will find answers to your questions.

FAQs about the Prague to Brussels bus

How much does a Prague - Brussels coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Prague - Brussels bus trip is available from £20 and takes 18h 5m. Compare offers and save money!

How much could I save by comparing buses from Prague to Brussels?

The connection Prague to Brussels is offered by 2 companies with ticket prices ranging from £20 to £263. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Prague - Brussels route on average every day?

Each day, the bus route from Prague to Brussels is offered by roughly 37 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Brussels from Prague take?

The quickest coach from Prague to Brussels is provided by FlixBus and takes 13h 29m. Coach tickets for this connection cost £50. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Prague to Brussels?

The earliest bus to Brussels departs from Prague at 01:45. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Prague to Brussels?

The latest bus to Brussels departs from Prague at 23:50. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Prague - Brussels route?

Passengers looking to travel from Prague to Brussels can travel with FlixBus and European Sleeper. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Prague and Brussels?

You can check all the direct connections between Prague and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and European Sleeper.

What can I take with me on the bus to Brussels from Prague?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Prague Brussels bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Brussels on your planned travel date.

How does CheckMyBus find the best bus deals from Prague to Brussels?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 37 daily trips between Prague and Brussels. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Prague to Brussels?

Prices and availability for 37 trips between Prague and Brussels change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Prague to Brussels

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Brussels

Here’s an overview of the most popular bus routes to Prague and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus from Rijeka to Prague Bus from Rijeka to Prague
Coaches Lille to Prague Coaches Lille to Prague
Buses Vilnius to Prague Buses Vilnius to Prague
Bus to Prague from Usti nad Labem Bus to Prague from Usti nad Labem
Bus from Basel to Brussels Bus from Basel to Brussels
Buses Aberdeen to Brussels Buses Aberdeen to Brussels
Coaches Dunkirk to Brussels Coaches Dunkirk to Brussels
Coaches Madrid to Brussels Coaches Madrid to Brussels
Popular Airport Transfers to Prague and to Brussels
CheckMyBus › Coaches in Czech Republic › Coach to Prague › Coach to Brussels

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