Compare all timetables for the bus from Prague to Brussels
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 13h 20m | 11:05 | Prague | ÚAN Florenc | 00:25 | Brussels | North Station | Economy | £42 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 03/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 04/02/2026 00:25:00. 50 Economy ticket for £42 per person are available. Travel duration is 13h 20m
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| FlixBus | 15h 5m | 16:15 | Prague | ÚAN Florenc | 07:20 | Brussels | Midi Bus Station | Economy | £46 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 03/02/2026 16:15:00 to Midi Bus Station, Brussels (Belgium) arriving at 04/02/2026 07:20:00. 50 Economy ticket for £46 per person are available. Travel duration is 15h 5m
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| FlixBus | 18h 0m | 20:40 | Prague | Na Knížecí Station | 14:40 | Brussels | North Station | Economy | £58 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 03/02/2026 20:40:00 to North Station, Brussels (Belgium) arriving at 04/02/2026 14:40:00. 50 Economy ticket for £58 per person are available. Travel duration is 18h 0m
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| European Sleeper | 16h 28m | 18:00 | Prague | Wilsonova Coach Station | 10:28 | Brussels | Midi Bus Station | Economy | £207 |
A Bus from European Sleeper goes from Wilsonova Coach Station, Prague (Czech Republic) at 03/02/2026 18:00:00 to Midi Bus Station, Brussels (Belgium) arriving at 04/02/2026 10:28:00. 50 Economy ticket for £207 per person are available. Travel duration is 16h 28m
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FlixBus13h 20m011:05PragueÚAN Florenc22:30MaastrichtMeerssenerweg0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 04/02/2026 11:05:00 to Meerssenerweg, Maastricht (Netherlands) arriving at 04/02/2026 22:30:00. 50 Economy ticket for £29 per person are available. Travel duration is 11h 25m
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FlixBus1h 45m022:40MaastrichtMeerssenerweg00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Meerssenerweg, Maastricht (Netherlands) at 04/02/2026 22:40:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 00:25:00. 50 Economy ticket for £6 per person are available. Travel duration is 1h 45m
Waiting Time 0h 10m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 13h 20m | 11:05 | Prague | ÚAN Florenc | 00:25 | Brussels | North Station | Economy | £36 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 04/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 00:25:00. 50 Economy ticket for £36 per person are available. Travel duration is 13h 20m
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| FlixBus | 15h 5m | 16:15 | Prague | ÚAN Florenc | 07:20 | Brussels | Midi Bus Station | Economy | £38 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 04/02/2026 16:15:00 to Midi Bus Station, Brussels (Belgium) arriving at 05/02/2026 07:20:00. 50 Economy ticket for £38 per person are available. Travel duration is 15h 5m
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| FlixBus | 18h 15m | 22:15 | Prague | Na Knížecí Station | 16:30 | Brussels | North Station | Economy | £47 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 04/02/2026 22:15:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 16:30:00. 50 Economy ticket for £47 per person are available. Travel duration is 18h 15m
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| FlixBus | 16h 40m | 10:55 | Prague | Na Knížecí Station | 03:35 | Brussels | Midi Bus Station | Economy | £47 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 04/02/2026 10:55:00 to Midi Bus Station, Brussels (Belgium) arriving at 05/02/2026 03:35:00. 50 Economy ticket for £47 per person are available. Travel duration is 16h 40m
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| FlixBus | 16h 30m | 11:05 | Prague | ÚAN Florenc | 03:35 | Brussels | Midi Bus Station | Economy | £47 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 04/02/2026 11:05:00 to Midi Bus Station, Brussels (Belgium) arriving at 05/02/2026 03:35:00. 50 Economy ticket for £47 per person are available. Travel duration is 16h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 13h 20m | 11:05 | Prague | ÚAN Florenc | 00:25 | Brussels | North Station | Economy | £42 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 05/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 06/02/2026 00:25:00. 50 Economy ticket for £42 per person are available. Travel duration is 13h 20m
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| FlixBus | 14h 15m | 03:50 | Prague | Wilsonova Coach Station | 18:05 | Brussels | North Station | Economy | £44 |
A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 05/02/2026 03:50:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 18:05:00. 50 Economy ticket for £44 per person are available. Travel duration is 14h 15m
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| FlixBus | 13h 55m | 04:10 | Prague | Na Knížecí Station | 18:05 | Brussels | North Station | Economy | £44 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 05/02/2026 04:10:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 18:05:00. 50 Economy ticket for £44 per person are available. Travel duration is 13h 55m
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| European Sleeper | 15h 27m | 18:00 | Prague | Wilsonova Coach Station | 09:27 | Brussels | Midi Bus Station | Economy | £230 |
A Bus from European Sleeper goes from Wilsonova Coach Station, Prague (Czech Republic) at 05/02/2026 18:00:00 to Midi Bus Station, Brussels (Belgium) arriving at 06/02/2026 09:27:00. 50 Economy ticket for £230 per person are available. Travel duration is 15h 27m
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FlixBus13h 20m011:05PragueÚAN Florenc22:30MaastrichtMeerssenerweg0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 04/02/2026 11:05:00 to Meerssenerweg, Maastricht (Netherlands) arriving at 04/02/2026 22:30:00. 50 Economy ticket for £29 per person are available. Travel duration is 11h 25m
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FlixBus1h 45m022:40MaastrichtMeerssenerweg00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Meerssenerweg, Maastricht (Netherlands) at 04/02/2026 22:40:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 00:25:00. 50 Economy ticket for £6 per person are available. Travel duration is 1h 45m
Waiting Time 0h 10m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 14h 15m | 03:50 | Prague | Wilsonova Coach Station | 18:05 | Brussels | North Station | Economy | £46 |
A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 06/02/2026 03:50:00 to North Station, Brussels (Belgium) arriving at 06/02/2026 18:05:00. 50 Economy ticket for £46 per person are available. Travel duration is 14h 15m
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| FlixBus | 13h 55m | 04:10 | Prague | Na Knížecí Station | 18:05 | Brussels | North Station | Economy | £46 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 06/02/2026 04:10:00 to North Station, Brussels (Belgium) arriving at 06/02/2026 18:05:00. 50 Economy ticket for £46 per person are available. Travel duration is 13h 55m
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| FlixBus | 14h 50m | 23:05 | Prague | ÚAN Florenc | 13:55 | Brussels | Midi Bus Station | Economy | £49 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 06/02/2026 23:05:00 to Midi Bus Station, Brussels (Belgium) arriving at 07/02/2026 13:55:00. 50 Economy ticket for £49 per person are available. Travel duration is 14h 50m
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| FlixBus | 13h 20m | 11:05 | Prague | ÚAN Florenc | 00:25 | Brussels | North Station | Economy | £49 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 06/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 00:25:00. 50 Economy ticket for £49 per person are available. Travel duration is 13h 20m
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| FlixBus | 15h 5m | 16:15 | Prague | ÚAN Florenc | 07:20 | Brussels | Midi Bus Station | Economy | £50 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 06/02/2026 16:15:00 to Midi Bus Station, Brussels (Belgium) arriving at 07/02/2026 07:20:00. 50 Economy ticket for £50 per person are available. Travel duration is 15h 5m
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FlixBus13h 20m011:05PragueÚAN Florenc22:30MaastrichtMeerssenerweg0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 04/02/2026 11:05:00 to Meerssenerweg, Maastricht (Netherlands) arriving at 04/02/2026 22:30:00. 50 Economy ticket for £29 per person are available. Travel duration is 11h 25m
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FlixBus1h 45m022:40MaastrichtMeerssenerweg00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Meerssenerweg, Maastricht (Netherlands) at 04/02/2026 22:40:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 00:25:00. 50 Economy ticket for £6 per person are available. Travel duration is 1h 45m
Waiting Time 0h 10m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 13h 20m | 10:35 | Prague | ÚAN Florenc | 23:55 | Brussels | North Station | Economy | £42 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 07/02/2026 10:35:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 23:55:00. 50 Economy ticket for £42 per person are available. Travel duration is 13h 20m
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| FlixBus | 14h 15m | 03:50 | Prague | Wilsonova Coach Station | 18:05 | Brussels | North Station | Economy | £44 |
A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 07/02/2026 03:50:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 18:05:00. 50 Economy ticket for £44 per person are available. Travel duration is 14h 15m
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| FlixBus | 13h 55m | 04:10 | Prague | Na Knížecí Station | 18:05 | Brussels | North Station | Economy | £44 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 07/02/2026 04:10:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 18:05:00. 50 Economy ticket for £44 per person are available. Travel duration is 13h 55m
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| FlixBus | 15h 5m | 16:15 | Prague | ÚAN Florenc | 07:20 | Brussels | Midi Bus Station | Economy | £47 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 07/02/2026 16:15:00 to Midi Bus Station, Brussels (Belgium) arriving at 08/02/2026 07:20:00. 50 Economy ticket for £47 per person are available. Travel duration is 15h 5m
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| FlixBus | 14h 50m | 23:05 | Prague | ÚAN Florenc | 13:55 | Brussels | Midi Bus Station | Economy | £47 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 07/02/2026 23:05:00 to Midi Bus Station, Brussels (Belgium) arriving at 08/02/2026 13:55:00. 50 Economy ticket for £47 per person are available. Travel duration is 14h 50m
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FlixBus13h 20m011:05PragueÚAN Florenc22:30MaastrichtMeerssenerweg0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 04/02/2026 11:05:00 to Meerssenerweg, Maastricht (Netherlands) arriving at 04/02/2026 22:30:00. 50 Economy ticket for £29 per person are available. Travel duration is 11h 25m
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FlixBus1h 45m022:40MaastrichtMeerssenerweg00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Meerssenerweg, Maastricht (Netherlands) at 04/02/2026 22:40:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 00:25:00. 50 Economy ticket for £6 per person are available. Travel duration is 1h 45m
Waiting Time 0h 10m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 14h 15m | 03:50 | Prague | Wilsonova Coach Station | 18:05 | Brussels | North Station | Economy | £44 |
A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 08/02/2026 03:50:00 to North Station, Brussels (Belgium) arriving at 08/02/2026 18:05:00. 50 Economy ticket for £44 per person are available. Travel duration is 14h 15m
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| FlixBus | 13h 55m | 04:10 | Prague | Na Knížecí Station | 18:05 | Brussels | North Station | Economy | £44 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 08/02/2026 04:10:00 to North Station, Brussels (Belgium) arriving at 08/02/2026 18:05:00. 50 Economy ticket for £44 per person are available. Travel duration is 13h 55m
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| FlixBus | 14h 50m | 23:05 | Prague | ÚAN Florenc | 13:55 | Brussels | Midi Bus Station | Economy | £49 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 08/02/2026 23:05:00 to Midi Bus Station, Brussels (Belgium) arriving at 09/02/2026 13:55:00. 50 Economy ticket for £49 per person are available. Travel duration is 14h 50m
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| European Sleeper | 15h 27m | 18:00 | Prague | Wilsonova Coach Station | 09:27 | Brussels | Midi Bus Station | Economy | £621 |
A Bus from European Sleeper goes from Wilsonova Coach Station, Prague (Czech Republic) at 08/02/2026 18:00:00 to Midi Bus Station, Brussels (Belgium) arriving at 09/02/2026 09:27:00. 50 Economy ticket for £621 per person are available. Travel duration is 15h 27m
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FlixBus13h 20m011:05PragueÚAN Florenc22:30MaastrichtMeerssenerweg0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 04/02/2026 11:05:00 to Meerssenerweg, Maastricht (Netherlands) arriving at 04/02/2026 22:30:00. 50 Economy ticket for £29 per person are available. Travel duration is 11h 25m
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FlixBus1h 45m022:40MaastrichtMeerssenerweg00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Meerssenerweg, Maastricht (Netherlands) at 04/02/2026 22:40:00 to North Station, Brussels (Belgium) arriving at 05/02/2026 00:25:00. 50 Economy ticket for £6 per person are available. Travel duration is 1h 45m
Waiting Time 0h 10m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 14h 15m | 03:50 | Prague | Wilsonova Coach Station | 18:05 | Brussels | North Station | Economy | £36 |
A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 09/02/2026 03:50:00 to North Station, Brussels (Belgium) arriving at 09/02/2026 18:05:00. 50 Economy ticket for £36 per person are available. Travel duration is 14h 15m
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| FlixBus | 13h 55m | 04:10 | Prague | Na Knížecí Station | 18:05 | Brussels | North Station | Economy | £36 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 09/02/2026 04:10:00 to North Station, Brussels (Belgium) arriving at 09/02/2026 18:05:00. 50 Economy ticket for £36 per person are available. Travel duration is 13h 55m
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| FlixBus | 13h 20m | 11:05 | Prague | ÚAN Florenc | 00:25 | Brussels | North Station | Economy | £36 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 09/02/2026 11:05:00 to North Station, Brussels (Belgium) arriving at 10/02/2026 00:25:00. 50 Economy ticket for £36 per person are available. Travel duration is 13h 20m
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| FlixBus | 15h 5m | 16:15 | Prague | ÚAN Florenc | 07:20 | Brussels | Midi Bus Station | Economy | £38 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 09/02/2026 16:15:00 to Midi Bus Station, Brussels (Belgium) arriving at 10/02/2026 07:20:00. 50 Economy ticket for £38 per person are available. Travel duration is 15h 5m
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| FlixBus | 17h 0m | 01:45 | Prague | Wilsonova Coach Station | 18:45 | Brussels | North Station | Economy | £46 |
A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 09/02/2026 01:45:00 to North Station, Brussels (Belgium) arriving at 09/02/2026 18:45:00. 50 Economy ticket for £46 per person are available. Travel duration is 17h 0m
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Best Price Offer: The price for the cheapest coach from Prague to Brussels is £32 on 17/02/2026. Flexible travellers save on ticket prices.
Frequency of bus connections between Prague and Brussels
Facts about coaches from Prague to Brussels
Compare all providers like FlixBus and European Sleeper that travel 26 times every day by bus from Prague to Brussels in one click! Book your bus ticket from Prague to Brussels starting from £32!
| Cheapest Bus | £32 |
| Fastest Bus | 13h 20m |
| Earliest Coach | 07:55 |
| Latest Coach | 20:40 |
| Daily Bus Connections | 26 Ø |
| Distance | 718.5 km |
| Coach Companies | FlixBus and European Sleeper |
Cheapest coach connections from Prague to Brussels
Every day, 26 buses from 2 coach companies leave Prague for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/02/2026 and for the following days.
The cheapest time to travel from Prague to Brussels
How to save money travelling from Prague to Brussels
Book the ticket from Prague to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Brussels, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Prague to Brussels are also emptier.All bus stations and stops in Prague and Brussels
The map below shows you where to find all the bus stations in Prague and Brussels.
Compare the bus with other modes of transport
Service and Comfort on the bus from Prague to Brussels
FAQs about the Prague to Brussels bus
How much does a Prague - Brussels coach trip cost?
How much could I save by comparing buses from Prague to Brussels?
How many connections are available for the Prague - Brussels route on average every day?
How long does a bus to Brussels from Prague take?
What time is the first bus from Prague to Brussels?
What time is the last coach from Prague to Brussels?
Which bus companies serve the Prague - Brussels route?
Is there a direct bus between Prague and Brussels?
What can I take with me on the bus to Brussels from Prague?
What equipment is available for the Prague Brussels bus route?
How does CheckMyBus find the best bus deals from Prague to Brussels?
How does CheckMyBus technology work for trips from Prague to Brussels?
Available seat classes which are offered on the bus route Prague to Brussels
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Prague and to Brussels
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