Bus tickets Prague to Brussels from £36

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Compare all timetables for the bus from Prague to Brussels

Here is a selection of the cheapest bus trips from the schedule from Prague to Brussels from various bus operators like FlixBus or European Sleeper for the next days.

today
£50
tomorrow
£49
Monday
£38
Tuesday
£37
Wednesday
£37
Thursday
£36
Friday
£42

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 20m 10:35 Prague ÚAN Florenc 23:55 Brussels North Station  Economy £50
FlixBus 14h 15m 03:50 Prague Wilsonova Coach Station 18:05 Brussels North Station  Economy £52
FlixBus 17h 40m 13:05 Prague Wilsonova Coach Station 06:45 Brussels North Station  Economy £52
FlixBus 17h 45m 14:45 Prague Wilsonova Coach Station 08:30 Brussels North Station  Economy £52
FlixBus 16h 0m 17:30 Prague Wilsonova Coach Station 09:30 Brussels North Station  Economy £52
  • Did you know that if you travel from Prague to Brussels via Maastricht, you can save more than £10? You can find the corresponding connections below.
    • FlixBus
      13h 20m
      0
      11:05
      Prague
      ÚAN Florenc
      22:30
      Maastricht
      Meerssenerweg
      0
      FlixBus
      Economy
      £33
      • Waiting Time 0h 10m
    • FlixBus
      1h 45m
      0
      22:40
      Maastricht
      Meerssenerweg
      00:25
      Brussels
      North Station
      0
      FlixBus
      Economy
      £7
    Travel time is the same as the direct connection, but you will save £10

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 20m 11:05 Prague ÚAN Florenc 00:25 Brussels North Station  Economy £49
FlixBus 14h 15m 03:50 Prague Wilsonova Coach Station 18:05 Brussels North Station  Economy £58
FlixBus 13h 55m 04:10 Prague Na Knížecí Station 18:05 Brussels North Station  Economy £58
European Sleeper 15h 27m 18:00 Prague Wilsonova Coach Station 09:27 Brussels Midi Bus Station  Economy £224
  • Did you know that if you travel from Prague to Brussels via Maastricht, you can save more than £15? You can find the corresponding connections below.
    • FlixBus
      13h 20m
      0
      11:05
      Prague
      ÚAN Florenc
      22:30
      Maastricht
      Meerssenerweg
      0
      FlixBus
      Economy
      £28
      • Waiting Time 0h 10m
    • FlixBus
      1h 45m
      0
      22:40
      Maastricht
      Meerssenerweg
      00:25
      Brussels
      North Station
      0
      FlixBus
      Economy
      £6
    Travel time is the same as the direct connection, but you will save £15

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 20m 11:05 Prague ÚAN Florenc 00:25 Brussels North Station  Economy £38
FlixBus 14h 15m 03:50 Prague Wilsonova Coach Station 18:05 Brussels North Station  Economy £39
FlixBus 13h 55m 04:10 Prague Na Knížecí Station 18:05 Brussels North Station  Economy £39
FlixBus 15h 5m 16:15 Prague ÚAN Florenc 07:20 Brussels Midi Bus Station  Economy £39
FlixBus 15h 15m 09:10 Prague Na Knížecí Station 00:25 Brussels North Station  Economy £49
  • Did you know that if you travel from Prague to Brussels via Maastricht, you can save more than £4? You can find the corresponding connections below.
    • FlixBus
      13h 20m
      0
      11:05
      Prague
      ÚAN Florenc
      22:30
      Maastricht
      Meerssenerweg
      0
      FlixBus
      Economy
      £28
      • Waiting Time 0h 10m
    • FlixBus
      1h 45m
      0
      22:40
      Maastricht
      Meerssenerweg
      00:25
      Brussels
      North Station
      0
      FlixBus
      Economy
      £6
    Travel time is the same as the direct connection, but you will save £4

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 20m 11:05 Prague ÚAN Florenc 00:25 Brussels North Station  Economy £37
FlixBus 15h 5m 16:15 Prague ÚAN Florenc 07:20 Brussels Midi Bus Station  Economy £39
FlixBus 15h 15m 09:10 Prague Na Knížecí Station 00:25 Brussels North Station  Economy £49
European Sleeper 16h 27m 18:00 Prague Wilsonova Coach Station 10:27 Brussels Midi Bus Station  Economy £159

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 20m 11:05 Prague ÚAN Florenc 00:25 Brussels North Station  Economy £37
FlixBus 15h 5m 16:15 Prague ÚAN Florenc 07:20 Brussels Midi Bus Station  Economy £37
FlixBus 15h 30m 18:00 Prague ÚAN Florenc 09:30 Brussels North Station  Economy £46
FlixBus 15h 15m 09:10 Prague Na Knížecí Station 00:25 Brussels North Station  Economy £47
FlixBus 18h 40m 21:50 Prague Na Knížecí Station 16:30 Brussels North Station  Economy £47

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 13h 20m 11:05 Prague ÚAN Florenc 00:25 Brussels North Station  Economy £36
FlixBus 14h 15m 03:50 Prague Wilsonova Coach Station 18:05 Brussels North Station  Economy £37
FlixBus 13h 55m 04:10 Prague Na Knížecí Station 18:05 Brussels North Station  Economy £37
European Sleeper 15h 27m 18:00 Prague Wilsonova Coach Station 09:27 Brussels Midi Bus Station  Economy £468

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 15m 03:50 Prague Wilsonova Coach Station 18:05 Brussels North Station  Economy £42
FlixBus 13h 55m 04:10 Prague Na Knížecí Station 18:05 Brussels North Station  Economy £42
FlixBus 14h 50m 23:05 Prague ÚAN Florenc 13:55 Brussels Midi Bus Station  Economy £43
FlixBus 15h 5m 16:15 Prague ÚAN Florenc 07:20 Brussels Midi Bus Station  Economy £50
FlixBus 13h 20m 11:05 Prague ÚAN Florenc 00:25 Brussels North Station  Economy £52
  • Did you know that if you travel from Prague to Brussels via Maastricht, you can save more than £8? You can find the corresponding connections below.
    • FlixBus
      13h 20m
      0
      11:05
      Prague
      ÚAN Florenc
      22:30
      Maastricht
      Meerssenerweg
      0
      FlixBus
      Economy
      £28
      • Waiting Time 0h 10m
    • FlixBus
      1h 45m
      0
      22:40
      Maastricht
      Meerssenerweg
      00:25
      Brussels
      North Station
      0
      FlixBus
      Economy
      £6
    Travel time is the same as the direct connection, but you will save £8

Best Price Offer: The price for the cheapest coach from Prague to Brussels is £36 on 26/03/2026. Flexible travellers save on ticket prices.


Frequency of bus connections between Prague and Brussels

See here how frequent the connections between Prague and Brussels are, during different times and days of the week.
Saturday is the busiest day, with more than 34 daily coaches from Prague to Brussels. Tuesday has instead the fewest connections, with only 16 daily coaches between Prague and Brussels.
The busiest time of the day is the Afternoon, with 65 coaches from Prague to Brussels, while Night sees the fewest connections between Prague and Brussels, with 19 offers.

Facts about coaches from Prague to Brussels

Compare all providers like FlixBus and European Sleeper that travel 26 times every day by bus from Prague to Brussels in one click! Book your bus ticket from Prague to Brussels starting from £36!

Cheapest Bus £36
Fastest Bus 13h 20m
Earliest Coach 01:45
Latest Coach 23:05
Daily Bus Connections 26 Ø
Distance 718.5 km
Coach Companies FlixBus and European Sleeper

Cheapest coach connections from Prague to Brussels

Every day, 26 buses from 2 coach companies leave Prague for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 21/03/2026 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 16/03
Tuesday 17/03
Wednesday 18/03
Thursday 19/03
Friday 20/03
Saturday 21/03
£50
Sunday 22/03
£49
Monday 23/03
£38
Tuesday 24/03
£37
Wednesday 25/03
£37
Thursday 26/03
£36
Friday 27/03
£42
Saturday 28/03
£44
Sunday 29/03
£41
Monday 30/03
£39
Tuesday 31/03
£41
Wednesday 01/04
£46
Thursday 02/04
£56
Friday 03/04
£56
Saturday 04/04
£55
Sunday 05/04
£58
Monday 06/04
£63
Tuesday 07/04
£46
Wednesday 08/04
£42
Thursday 09/04
£41
Friday 10/04
£42
Saturday 11/04
£38
Sunday 12/04

The cheapest time to travel from Prague to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Prague to Brussels, for the next 30 days.
With a price starting from £31, Wednesday is the cheapest day for a coach from Prague to Brussels. Friday instead is the most expensive day with prices starting from £42.
Night is the cheapest day time for bus tickets from Prague to Brussels, with £31. Afternoon is the most expensive time of the day with prices starting from £37.

How to save money travelling from Prague to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Prague to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Prague to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Prague to Brussels are also emptier.

All bus stations and stops in Prague and Brussels

The map below shows you where to find all the bus stations in Prague and Brussels.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Prague to Brussels? Compare all modes of transports from Prague to Brussels.

Service and Comfort on the bus from Prague to Brussels

Want to know which seat classes are available on the coaches from Prague to Brussels? Or which bus companies serve the route Prague to Brussels? Below you will find answers to your questions.

FAQs about the Prague to Brussels bus

How much does a Prague - Brussels coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Prague - Brussels bus trip is available from £36 and takes 13h 20m. Compare offers and save money!

How much could I save by comparing buses from Prague to Brussels?

The connection Prague to Brussels is offered by 2 companies with ticket prices ranging from £36 to £468. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Prague - Brussels route on average every day?

Each day, the bus route from Prague to Brussels is offered by roughly 26 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Brussels from Prague take?

The quickest coach from Prague to Brussels is provided by FlixBus and takes 13h 20m. Coach tickets for this connection cost £50. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Prague to Brussels?

The earliest bus to Brussels departs from Prague at 01:45. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Prague to Brussels?

The latest bus to Brussels departs from Prague at 23:05. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Prague - Brussels route?

Passengers looking to travel from Prague to Brussels can travel with FlixBus and European Sleeper. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Prague and Brussels?

You can check all the direct connections between Prague and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and European Sleeper.

What can I take with me on the bus to Brussels from Prague?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Prague Brussels bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Prague Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Prague to Brussels on your planned travel date.

How does CheckMyBus find the best bus deals from Prague to Brussels?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 26 daily trips between Prague and Brussels. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Prague to Brussels?

Prices and availability for 26 trips between Prague and Brussels change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Prague to Brussels

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Prague and to Brussels

Here’s an overview of the most popular bus routes to Prague and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!
Coaches Zgorzelec to Prague Coaches Zgorzelec to Prague
Bus to Prague from Most Bus to Prague from Most
Bus from Middlesbrough to Prague Bus from Middlesbrough to Prague
Coach from Ceske Budejovice to Prague Coach from Ceske Budejovice to Prague
Coach to Brussels from Eindhoven Coach to Brussels from Eindhoven
Bus from Mainz to Brussels Bus from Mainz to Brussels
Bus Nantes to Brussels Bus Nantes to Brussels
Buses Exeter to Brussels Buses Exeter to Brussels
Popular Airport Transfers to Prague and to Brussels
CheckMyBus › Coaches in Czech Republic › Coach to Prague › Coach to Brussels

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