Bus and Coach from Pittsburgh to Chicago: Compare all prices

Compare all timetables for the bus from Pittsburgh to Chicago

Here is a selection of the cheapest bus trips from the schedule from Pittsburgh to Chicago from various bus operators like Greyhound US or FlixBus for the next days.

today

£52

tomorrow

£44

Thursday

£43

Friday

£42

Saturday

£42

Sunday

£38

Monday

£37

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	15h 45m	08:50	Pittsburgh	Grant Street Transportation Center	23:35	Chicago	95th Red Line Station	Economy	£52	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 08/09/2026 08:50:00 to 95th Red Line Station, Chicago (USA) arriving at 08/09/2026 23:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 15h 45m
Greyhound US	12h 15m	08:50	Pittsburgh	Grant Street Transportation Center	20:05	Chicago	Downtown Coach Station	Economy	£55	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 08/09/2026 08:50:00 to Downtown Coach Station, Chicago (USA) arriving at 08/09/2026 20:05:00. 50 Economy ticket for £55 per person are available. Travel duration is 12h 15m
FlixBus	12h 45m	07:10	Pittsburgh	Grant Street Transportation Center	18:55	Chicago	Downtown Coach Station	Economy	£61	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 08/09/2026 07:10:00 to Downtown Coach Station, Chicago (USA) arriving at 08/09/2026 18:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 12h 45m
Greyhound US	12h 30m	08:35	Pittsburgh	Grant Street Transportation Center	20:05	Chicago	Downtown Coach Station	Economy	£63	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 08/09/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 08/09/2026 20:05:00. 50 Economy ticket for £63 per person are available. Travel duration is 12h 30m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 15m	08:50	Pittsburgh	Grant Street Transportation Center	20:05	Chicago	Downtown Coach Station	Economy	£44	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 09/09/2026 08:50:00 to Downtown Coach Station, Chicago (USA) arriving at 09/09/2026 20:05:00. 50 Economy ticket for £44 per person are available. Travel duration is 12h 15m
Greyhound US	13h 25m	20:00	Pittsburgh	Grant Street Transportation Center	08:25	Chicago	Downtown Coach Station	Economy	£45	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 09/09/2026 20:00:00 to Downtown Coach Station, Chicago (USA) arriving at 10/09/2026 08:25:00. 50 Economy ticket for £45 per person are available. Travel duration is 13h 25m
Greyhound US	13h 0m	20:00	Pittsburgh	Grant Street Transportation Center	08:00	Chicago	Canal & Van Buren	Economy	£45	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 09/09/2026 20:00:00 to Canal & Van Buren, Chicago (USA) arriving at 10/09/2026 08:00:00. 50 Economy ticket for £45 per person are available. Travel duration is 13h 0m
FlixBus	11h 25m	19:45	Pittsburgh	Grant Street Transportation Center	06:10	Chicago	Downtown Coach Station	Economy	£46	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 09/09/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 10/09/2026 06:10:00. 50 Economy ticket for £46 per person are available. Travel duration is 11h 25m
FlixBus	12h 45m	07:10	Pittsburgh	Grant Street Transportation Center	18:55	Chicago	Downtown Coach Station	Economy	£52	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 09/09/2026 07:10:00 to Downtown Coach Station, Chicago (USA) arriving at 09/09/2026 18:55:00. 50 Economy ticket for £52 per person are available. Travel duration is 12h 45m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 30m	08:35	Pittsburgh	Grant Street Transportation Center	20:05	Chicago	Downtown Coach Station	Economy	£43	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 10/09/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 10/09/2026 20:05:00. 50 Economy ticket for £43 per person are available. Travel duration is 12h 30m
FlixBus	11h 25m	19:45	Pittsburgh	Grant Street Transportation Center	06:10	Chicago	Downtown Coach Station	Economy	£43	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 10/09/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 11/09/2026 06:10:00. 50 Economy ticket for £43 per person are available. Travel duration is 11h 25m
Greyhound US	10h 5m	00:55	Pittsburgh	Grant Street Transportation Center	10:00	Chicago	Downtown Coach Station	Economy	£44	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 10/09/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 10/09/2026 10:00:00. 50 Economy ticket for £44 per person are available. Travel duration is 10h 5m
Greyhound US	13h 0m	01:25	Pittsburgh	Grant Street Transportation Center	13:25	Chicago	Downtown Coach Station	Economy	£48	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 10/09/2026 01:25:00 to Downtown Coach Station, Chicago (USA) arriving at 10/09/2026 13:25:00. 50 Economy ticket for £48 per person are available. Travel duration is 13h 0m
FlixBus	12h 45m	07:10	Pittsburgh	Grant Street Transportation Center	18:55	Chicago	Downtown Coach Station	Economy	£50	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 10/09/2026 07:10:00 to Downtown Coach Station, Chicago (USA) arriving at 10/09/2026 18:55:00. 50 Economy ticket for £50 per person are available. Travel duration is 12h 45m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 30m	08:35	Pittsburgh	Grant Street Transportation Center	20:05	Chicago	Downtown Coach Station	Economy	£42	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 11/09/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 11/09/2026 20:05:00. 50 Economy ticket for £42 per person are available. Travel duration is 12h 30m
Greyhound US	10h 5m	00:55	Pittsburgh	Grant Street Transportation Center	10:00	Chicago	Downtown Coach Station	Economy	£43	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 11/09/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 11/09/2026 10:00:00. 50 Economy ticket for £43 per person are available. Travel duration is 10h 5m
FlixBus	11h 25m	19:45	Pittsburgh	Grant Street Transportation Center	06:10	Chicago	Downtown Coach Station	Economy	£44	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 11/09/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 12/09/2026 06:10:00. 50 Economy ticket for £44 per person are available. Travel duration is 11h 25m
Greyhound US	13h 0m	01:25	Pittsburgh	Grant Street Transportation Center	13:25	Chicago	Downtown Coach Station	Economy	£55	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 11/09/2026 01:25:00 to Downtown Coach Station, Chicago (USA) arriving at 11/09/2026 13:25:00. 50 Economy ticket for £55 per person are available. Travel duration is 13h 0m
FlixBus	12h 55m	07:00	Pittsburgh	Grant Street Transportation Center	18:55	Chicago	Downtown Coach Station	Economy	£57	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 11/09/2026 07:00:00 to Downtown Coach Station, Chicago (USA) arriving at 11/09/2026 18:55:00. 50 Economy ticket for £57 per person are available. Travel duration is 12h 55m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	10h 5m	00:55	Pittsburgh	Grant Street Transportation Center	10:00	Chicago	Downtown Coach Station	Economy	£42	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/09/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 12/09/2026 10:00:00. 50 Economy ticket for £42 per person are available. Travel duration is 10h 5m
Greyhound US	12h 30m	08:35	Pittsburgh	Grant Street Transportation Center	20:05	Chicago	Downtown Coach Station	Economy	£42	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/09/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 12/09/2026 20:05:00. 50 Economy ticket for £42 per person are available. Travel duration is 12h 30m
FlixBus	11h 25m	19:45	Pittsburgh	Grant Street Transportation Center	06:10	Chicago	Downtown Coach Station	Economy	£42	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/09/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 13/09/2026 06:10:00. 50 Economy ticket for £42 per person are available. Travel duration is 11h 25m
FlixBus	12h 55m	07:00	Pittsburgh	Grant Street Transportation Center	18:55	Chicago	Downtown Coach Station	Economy	£43	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/09/2026 07:00:00 to Downtown Coach Station, Chicago (USA) arriving at 12/09/2026 18:55:00. 50 Economy ticket for £43 per person are available. Travel duration is 12h 55m
Greyhound US	13h 0m	01:25	Pittsburgh	Grant Street Transportation Center	13:25	Chicago	Downtown Coach Station	Economy	£47	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 12/09/2026 01:25:00 to Downtown Coach Station, Chicago (USA) arriving at 12/09/2026 13:25:00. 50 Economy ticket for £47 per person are available. Travel duration is 13h 0m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	10h 5m	00:55	Pittsburgh	Grant Street Transportation Center	10:00	Chicago	Downtown Coach Station	Economy	£38	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 13/09/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 13/09/2026 10:00:00. 50 Economy ticket for £38 per person are available. Travel duration is 10h 5m
Greyhound US	12h 30m	08:35	Pittsburgh	Grant Street Transportation Center	20:05	Chicago	Downtown Coach Station	Economy	£38	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 13/09/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 13/09/2026 20:05:00. 50 Economy ticket for £38 per person are available. Travel duration is 12h 30m
FlixBus	11h 25m	19:45	Pittsburgh	Grant Street Transportation Center	06:10	Chicago	Downtown Coach Station	Economy	£42	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 13/09/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 14/09/2026 06:10:00. 50 Economy ticket for £42 per person are available. Travel duration is 11h 25m
FlixBus	12h 55m	07:00	Pittsburgh	Grant Street Transportation Center	18:55	Chicago	Downtown Coach Station	Economy	£44	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 13/09/2026 07:00:00 to Downtown Coach Station, Chicago (USA) arriving at 13/09/2026 18:55:00. 50 Economy ticket for £44 per person are available. Travel duration is 12h 55m
Greyhound US	13h 0m	01:25	Pittsburgh	Grant Street Transportation Center	13:25	Chicago	Downtown Coach Station	Economy	£49	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 13/09/2026 01:25:00 to Downtown Coach Station, Chicago (USA) arriving at 13/09/2026 13:25:00. 50 Economy ticket for £49 per person are available. Travel duration is 13h 0m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	10h 5m	00:55	Pittsburgh	Grant Street Transportation Center	10:00	Chicago	Downtown Coach Station	Economy	£37	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 14/09/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 14/09/2026 10:00:00. 50 Economy ticket for £37 per person are available. Travel duration is 10h 5m
Greyhound US	12h 30m	08:35	Pittsburgh	Grant Street Transportation Center	20:05	Chicago	Downtown Coach Station	Economy	£37	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 14/09/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 14/09/2026 20:05:00. 50 Economy ticket for £37 per person are available. Travel duration is 12h 30m
FlixBus	11h 25m	19:45	Pittsburgh	Grant Street Transportation Center	06:10	Chicago	Downtown Coach Station	Economy	£37	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 14/09/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 15/09/2026 06:10:00. 50 Economy ticket for £37 per person are available. Travel duration is 11h 25m
FlixBus	12h 55m	07:00	Pittsburgh	Grant Street Transportation Center	18:55	Chicago	Downtown Coach Station	Economy	£39	A Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 14/09/2026 07:00:00 to Downtown Coach Station, Chicago (USA) arriving at 14/09/2026 18:55:00. 50 Economy ticket for £39 per person are available. Travel duration is 12h 55m
Greyhound US	13h 0m	01:25	Pittsburgh	Grant Street Transportation Center	13:25	Chicago	Downtown Coach Station	Economy	£44	A Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 14/09/2026 01:25:00 to Downtown Coach Station, Chicago (USA) arriving at 14/09/2026 13:25:00. 50 Economy ticket for £44 per person are available. Travel duration is 13h 0m

Best Price Offer: The price for the cheapest coach from Pittsburgh to Chicago is £37 on 14/09/2026. Flexible travellers save on ticket prices.

Frequency of bus connections between Pittsburgh and Chicago

See here how frequent the connections between Pittsburgh and Chicago are, during different times and days of the week.

Wednesday is the busiest day, with more than 28 daily coaches from Pittsburgh to Chicago. Tuesday has instead the fewest connections, with only 14 daily coaches between Pittsburgh and Chicago.

The busiest time of the day is the Evening, with 63 coaches from Pittsburgh to Chicago, while Night sees the fewest connections between Pittsburgh and Chicago, with 47 offers.

Facts about coaches from Pittsburgh to Chicago

Compare all providers like Greyhound US and FlixBus that travel 23 times every day by bus from Pittsburgh to Chicago in one click! Book your bus ticket from Pittsburgh to Chicago starting from £37!

Cheapest Bus	£37
Fastest Bus	9h 5m
Earliest Coach	07:10
Latest Coach	20:00
Daily Bus Connections	23 Ø
Distance	659.2 km
Coach Companies	Greyhound US and FlixBus

Cheapest coach connections from Pittsburgh to Chicago

Every day, 23 buses from 2 coach companies leave Pittsburgh for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 08/09/2026 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 07/09

Tuesday 08/09

£52

Wednesday 09/09

£44

Thursday 10/09

£43

Friday 11/09

£42

Saturday 12/09

£42

Sunday 13/09

£58

Monday 14/09

£37

Tuesday 15/09

£37

Wednesday 16/09

£40

Thursday 17/09

£40

Friday 18/09

£44

Saturday 19/09

£40

Sunday 20/09

£41

Monday 21/09

£38

Tuesday 22/09

£37

Wednesday 23/09

£37

Thursday 24/09

£38

Friday 25/09

£52

Saturday 26/09

£39

Sunday 27/09

£54

Monday 28/09

£42

Tuesday 29/09

£45

Wednesday 30/09

£39

Thursday 01/10

£44

Friday 02/10

£42

Saturday 03/10

£46

Sunday 04/10

The cheapest time to travel from Pittsburgh to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from Pittsburgh to Chicago, for the next 30 days.

With a price starting from £37, Monday is the cheapest day for a coach from Pittsburgh to Chicago. Friday instead is the most expensive day with prices starting from £42.

Morning is the cheapest day time for bus tickets from Pittsburgh to Chicago, with £37. Morning is the most expensive time of the day with prices starting from £37.

How to save money travelling from Pittsburgh to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Pittsburgh to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Pittsburgh to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Pittsburgh to Chicago are also emptier.

Beloved bus companies from Pittsburgh to Chicago

These are the most booked bus companies between Pittsburgh to Chicago from our users.

FlixBus from Pittsburgh to Chicago

Here you will find the key facts about the FlixBus bus route Pittsburgh to Chicago:

Cheapest Price	£37
Fastest Coach	9h 55m
Earliest Coach	07:10
Last Coach	19:45
Daily Connections	5 Ø
Found on	01/09/2026

All bus stations and stops in Pittsburgh and Chicago

The map below shows you where to find all the bus stations in Pittsburgh and Chicago.

Grant Street Transportation Center

11th St 55

David L. Lawrence Convention Center

10th St Pittsburgh 131-199

Carnegie Mellon

Forbes Ave

University of

Bus Stop

Forbes Ave 3501

95th Red Line Station

W. 95th St 14

Downtown Coach Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Service and Comfort on the bus from Pittsburgh to Chicago

Want to know which seat classes are available on the coaches from Pittsburgh to Chicago? Or which bus companies serve the route Pittsburgh to Chicago? Below you will find answers to your questions.

FAQs about the Pittsburgh to Chicago bus

How much does a Pittsburgh - Chicago coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Pittsburgh - Chicago bus trip is available from £37 and takes 9h 5m. Compare offers and save money!

How much could I save by comparing buses from Pittsburgh to Chicago?

The connection Pittsburgh to Chicago is offered by 2 companies with ticket prices ranging from £37 to £84. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Pittsburgh - Chicago route on average every day?

Each day, the bus route from Pittsburgh to Chicago is offered by roughly 23 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Chicago from Pittsburgh take?

The quickest coach from Pittsburgh to Chicago is provided by Greyhound US and takes 9h 5m. Coach tickets for this connection cost £55. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Pittsburgh to Chicago?

The earliest bus to Chicago departs from Pittsburgh at 07:10. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Pittsburgh to Chicago?

The latest bus to Chicago departs from Pittsburgh at 20:00. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Pittsburgh - Chicago route?

Passengers looking to travel from Pittsburgh to Chicago can travel with Greyhound US and FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Pittsburgh and Chicago?

You can check all the direct connections between Pittsburgh and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the bus to Chicago from Pittsburgh?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Pittsburgh Chicago bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Pittsburgh Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Pittsburgh to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from Pittsburgh to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 23 daily trips between Pittsburgh and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Pittsburgh to Chicago?

Prices and availability for 23 trips between Pittsburgh and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Pittsburgh to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Pittsburgh and to Chicago

Here’s an overview of the most popular bus routes to Pittsburgh and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!