What is the best way to travel from Pittsburgh to Chicago?
Looking for a trip? Check and compare all the available Buses and Flights to Chicago from Pittsburgh. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Chicago from Pittsburgh?
You can reach Chicago with just £39 by taking a Bus from Greyhound US, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
-
Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 20/04/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 20/04/2026 10:00:00. 50 Economy ticket for £45 per person are available. Travel duration is 10h 5m
-
Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 20/04/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 20/04/2026 20:05:00. 50 Economy ticket for £45 per person are available. Travel duration is 12h 30m
-
FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 20/04/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 21/04/2026 06:10:00. 50 Economy ticket for £50 per person are available. Travel duration is 11h 25m
-
United Airlines1h 46m014:09Pittsburgh AirportPittsburgh Airport14:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 20/04/2026 14:09:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 20/04/2026 14:55:00. 50 Economy ticket for £66 per person are available. Travel duration is 1h 46m
-
Skyscanner2h 5m019:20Pittsburgh AirportPittsburgh Airport20:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 20/04/2026 19:20:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 20/04/2026 20:25:00. 50 Economy ticket for £66 per person are available. Travel duration is 2h 5m
-
United Airlines2h 5m019:20Pittsburgh AirportPittsburgh Airport20:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 20/04/2026 19:20:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 20/04/2026 20:25:00. 50 Economy ticket for £67 per person are available. Travel duration is 2h 5m
-
Skyscanner1h 53m016:07Pittsburgh AirportPittsburgh Airport17:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 20/04/2026 16:07:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 20/04/2026 17:00:00. 50 Economy ticket for £79 per person are available. Travel duration is 1h 53m
Cheapest Buses Monday
Cheapest Flights Monday
-
Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 21/04/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 21/04/2026 20:05:00. 50 Economy ticket for £44 per person are available. Travel duration is 12h 30m
-
Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 21/04/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 21/04/2026 10:00:00. 50 Economy ticket for £45 per person are available. Travel duration is 10h 5m
-
FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 21/04/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 22/04/2026 06:10:00. 50 Economy ticket for £50 per person are available. Travel duration is 11h 25m
-
American Airlines7h 11m012:25Pittsburgh AirportPittsburgh Airport18:36Chicago Midway AirportChicago Midway Airport0EconomyA Flight from American Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 21/04/2026 12:25:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 21/04/2026 18:36:00. 50 Economy ticket for £59 per person are available. Travel duration is 7h 11m
-
American Airlines1h 58m006:12Pittsburgh AirportPittsburgh Airport07:10Chicago Midway AirportChicago Midway Airport0EconomyA Flight from American Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 21/04/2026 06:12:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 21/04/2026 07:10:00. 50 Economy ticket for £77 per person are available. Travel duration is 1h 58m
-
United Airlines1h 49m007:00Pittsburgh AirportPittsburgh Airport07:49Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 21/04/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/04/2026 07:49:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 49m
-
United Airlines1h 46m010:49Pittsburgh AirportPittsburgh Airport11:35Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 21/04/2026 10:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/04/2026 11:35:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m014:09Pittsburgh AirportPittsburgh Airport14:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 21/04/2026 14:09:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/04/2026 14:55:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 46m
-
Skyscanner1h 56m008:54Pittsburgh AirportPittsburgh Airport09:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 21/04/2026 08:54:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/04/2026 09:50:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 56m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
-
Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 22/04/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 22/04/2026 10:00:00. 50 Economy ticket for £39 per person are available. Travel duration is 10h 5m
-
Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 22/04/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 22/04/2026 20:05:00. 50 Economy ticket for £39 per person are available. Travel duration is 12h 30m
-
FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 22/04/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 23/04/2026 06:10:00. 50 Economy ticket for £43 per person are available. Travel duration is 11h 25m
-
FlixBus10h 55m019:45PittsburghGrant Street Transportation Center05:40Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 22/04/2026 19:45:00 to 95th Red Line Station, Chicago (USA) arriving at 23/04/2026 05:40:00. 50 Economy ticket for £47 per person are available. Travel duration is 10h 55m
-
United Airlines1h 49m007:00Pittsburgh AirportPittsburgh Airport07:49Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 22/04/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 07:49:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 49m
-
United Airlines1h 46m010:49Pittsburgh AirportPittsburgh Airport11:35Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 22/04/2026 10:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 11:35:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m014:09Pittsburgh AirportPittsburgh Airport14:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 22/04/2026 14:09:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 14:55:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 46m
-
Skyscanner1h 56m008:54Pittsburgh AirportPittsburgh Airport09:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 22/04/2026 08:54:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 09:50:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 56m
-
Skyscanner1h 53m016:07Pittsburgh AirportPittsburgh Airport17:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 22/04/2026 16:07:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 17:00:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 53m
-
Spirit Airlines16h 39m006:35Pittsburgh AirportPittsburgh Airport22:14Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 22/04/2026 06:35:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 22/04/2026 22:14:00. 50 Economy ticket for £115 per person are available. Travel duration is 16h 39m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
-
Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 23/04/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 23/04/2026 20:05:00. 50 Economy ticket for £43 per person are available. Travel duration is 12h 30m
-
Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 23/04/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 23/04/2026 10:00:00. 50 Economy ticket for £45 per person are available. Travel duration is 10h 5m
-
Greyhound US14h 15m001:20PittsburghGrant Street Transportation Center14:35ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 23/04/2026 01:20:00 to Downtown Coach Station, Chicago (USA) arriving at 23/04/2026 14:35:00. 50 Economy ticket for £46 per person are available. Travel duration is 14h 15m
-
FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 23/04/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 06:10:00. 50 Economy ticket for £48 per person are available. Travel duration is 11h 25m
-
FlixBus10h 55m019:45PittsburghGrant Street Transportation Center05:40Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 23/04/2026 19:45:00 to 95th Red Line Station, Chicago (USA) arriving at 24/04/2026 05:40:00. 50 Economy ticket for £52 per person are available. Travel duration is 10h 55m
-
United Airlines1h 56m018:00Pittsburgh AirportPittsburgh Airport18:56Chicago Midway AirportChicago Midway Airport0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 23/04/2026 18:00:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 23/04/2026 18:56:00. 50 Economy ticket for £66 per person are available. Travel duration is 1h 56m
-
United Airlines1h 30m020:00Pittsburgh AirportPittsburgh Airport20:30Chicago Midway AirportChicago Midway Airport0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 23/04/2026 20:00:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 23/04/2026 20:30:00. 50 Economy ticket for £66 per person are available. Travel duration is 1h 30m
-
Spirit Airlines7h 9m018:15Pittsburgh AirportPittsburgh Airport00:24Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 23/04/2026 18:15:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 00:24:00. 50 Economy ticket for £83 per person are available. Travel duration is 7h 9m
-
Spirit Airlines37h 56m006:35Pittsburgh AirportPittsburgh Airport19:31Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 23/04/2026 06:35:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 24/04/2026 19:31:00. 50 Economy ticket for £124 per person are available. Travel duration is 37h 56m
-
Spirit Airlines26h 16m018:15Pittsburgh AirportPittsburgh Airport19:31Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 23/04/2026 18:15:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 24/04/2026 19:31:00. 50 Economy ticket for £124 per person are available. Travel duration is 26h 16m
-
United Airlines1h 49m007:00Pittsburgh AirportPittsburgh Airport07:49Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 23/04/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/04/2026 07:49:00. 50 Economy ticket for £127 per person are available. Travel duration is 1h 49m
Cheapest Buses Thursday
Cheapest Flights Thursday
-
Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 24/04/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 10:00:00. 50 Economy ticket for £47 per person are available. Travel duration is 10h 5m
-
Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 24/04/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 20:05:00. 50 Economy ticket for £49 per person are available. Travel duration is 12h 30m
-
FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 24/04/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 25/04/2026 06:10:00. 50 Economy ticket for £50 per person are available. Travel duration is 11h 25m
-
Greyhound US12h 15m008:50PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 24/04/2026 08:50:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 20:05:00. 50 Economy ticket for £60 per person are available. Travel duration is 12h 15m
-
United Airlines1h 49m007:00Pittsburgh AirportPittsburgh Airport07:49Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 24/04/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 07:49:00. 50 Economy ticket for £125 per person are available. Travel duration is 1h 49m
-
United Airlines1h 56m008:54Pittsburgh AirportPittsburgh Airport09:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 24/04/2026 08:54:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 09:50:00. 50 Economy ticket for £125 per person are available. Travel duration is 1h 56m
-
United Airlines1h 46m010:49Pittsburgh AirportPittsburgh Airport11:35Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 24/04/2026 10:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 11:35:00. 50 Economy ticket for £125 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m014:09Pittsburgh AirportPittsburgh Airport14:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 24/04/2026 14:09:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 14:55:00. 50 Economy ticket for £125 per person are available. Travel duration is 1h 46m
-
United Airlines1h 53m016:07Pittsburgh AirportPittsburgh Airport17:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 24/04/2026 16:07:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 17:00:00. 50 Economy ticket for £125 per person are available. Travel duration is 1h 53m
Cheapest Buses Friday
Cheapest Flights Friday
-
Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 25/04/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 25/04/2026 20:05:00. 50 Economy ticket for £50 per person are available. Travel duration is 12h 30m
-
Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 25/04/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 25/04/2026 10:00:00. 50 Economy ticket for £51 per person are available. Travel duration is 10h 5m
-
FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 25/04/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 26/04/2026 06:10:00. 50 Economy ticket for £51 per person are available. Travel duration is 11h 25m
-
Spirit Airlines7h 9m018:15Pittsburgh AirportPittsburgh Airport00:24Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 25/04/2026 18:15:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 00:24:00. 50 Economy ticket for £62 per person are available. Travel duration is 7h 9m
-
Frontier Airlines11h 23m012:44Pittsburgh AirportPittsburgh Airport23:07Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 25/04/2026 12:44:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 23:07:00. 50 Economy ticket for £83 per person are available. Travel duration is 11h 23m
-
United Airlines1h 49m007:00Pittsburgh AirportPittsburgh Airport07:49Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 25/04/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 07:49:00. 50 Economy ticket for £105 per person are available. Travel duration is 1h 49m
-
Skyscanner1h 56m008:54Pittsburgh AirportPittsburgh Airport09:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 25/04/2026 08:54:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 09:50:00. 50 Economy ticket for £105 per person are available. Travel duration is 1h 56m
-
Spirit Airlines13h 2m006:35Pittsburgh AirportPittsburgh Airport18:37Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 25/04/2026 06:35:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 25/04/2026 18:37:00. 50 Economy ticket for £118 per person are available. Travel duration is 13h 2m
-
Frontier Airlines22h 14m012:44Pittsburgh AirportPittsburgh Airport09:58Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 25/04/2026 12:44:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 26/04/2026 09:58:00. 50 Economy ticket for £130 per person are available. Travel duration is 22h 14m
Cheapest Buses Saturday
Cheapest Flights Saturday
-
Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 26/04/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 26/04/2026 10:00:00. 50 Economy ticket for £43 per person are available. Travel duration is 10h 5m
-
Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 26/04/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 26/04/2026 20:05:00. 50 Economy ticket for £44 per person are available. Travel duration is 12h 30m
-
FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 26/04/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 27/04/2026 06:10:00. 50 Economy ticket for £47 per person are available. Travel duration is 11h 25m
-
Spirit Airlines29h 4m018:15Pittsburgh AirportPittsburgh Airport22:19Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 26/04/2026 18:15:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 27/04/2026 22:19:00. 50 Economy ticket for £110 per person are available. Travel duration is 29h 4m
-
Allegiant Air15h 22m006:30Pittsburgh AirportPittsburgh Airport20:52Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Allegiant Air goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 26/04/2026 06:30:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 26/04/2026 20:52:00. 50 Economy ticket for £126 per person are available. Travel duration is 15h 22m
-
United Airlines1h 49m007:00Pittsburgh AirportPittsburgh Airport07:49Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 26/04/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 07:49:00. 50 Economy ticket for £136 per person are available. Travel duration is 1h 49m
-
United Airlines1h 46m010:49Pittsburgh AirportPittsburgh Airport11:35Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 26/04/2026 10:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 11:35:00. 50 Economy ticket for £136 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m014:09Pittsburgh AirportPittsburgh Airport14:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 26/04/2026 14:09:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 14:55:00. 50 Economy ticket for £136 per person are available. Travel duration is 1h 46m
-
Skyscanner1h 56m008:54Pittsburgh AirportPittsburgh Airport09:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 26/04/2026 08:54:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 09:50:00. 50 Economy ticket for £136 per person are available. Travel duration is 1h 56m
Cheapest Buses Sunday
Cheapest Flights Sunday
What are the fastest trips from Pittsburgh to Chicago?
You can get to Chicago from Pittsburgh in just 1h 30m with a Flight from United Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
-
United Airlines1h 46m014:09Pittsburgh AirportPittsburgh Airport14:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 20/04/2026 14:09:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 20/04/2026 14:55:00. 50 Economy ticket for £66 per person are available. Travel duration is 1h 46m
-
Skyscanner1h 53m016:07Pittsburgh AirportPittsburgh Airport17:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 20/04/2026 16:07:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 20/04/2026 17:00:00. 50 Economy ticket for £79 per person are available. Travel duration is 1h 53m
-
Skyscanner2h 5m019:20Pittsburgh AirportPittsburgh Airport20:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 20/04/2026 19:20:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 20/04/2026 20:25:00. 50 Economy ticket for £66 per person are available. Travel duration is 2h 5m
-
United Airlines2h 5m019:20Pittsburgh AirportPittsburgh Airport20:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 20/04/2026 19:20:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 20/04/2026 20:25:00. 50 Economy ticket for £67 per person are available. Travel duration is 2h 5m
-
Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 20/04/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 20/04/2026 10:00:00. 50 Economy ticket for £45 per person are available. Travel duration is 10h 5m
-
FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 20/04/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 21/04/2026 06:10:00. 50 Economy ticket for £50 per person are available. Travel duration is 11h 25m
-
Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 20/04/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 20/04/2026 20:05:00. 50 Economy ticket for £45 per person are available. Travel duration is 12h 30m
Fastest Flights Monday
Fastest Buses Monday
-
United Airlines1h 46m010:49Pittsburgh AirportPittsburgh Airport11:35Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 21/04/2026 10:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/04/2026 11:35:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m014:09Pittsburgh AirportPittsburgh Airport14:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 21/04/2026 14:09:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/04/2026 14:55:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 46m
-
United Airlines1h 49m007:00Pittsburgh AirportPittsburgh Airport07:49Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 21/04/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/04/2026 07:49:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 49m
-
Skyscanner1h 53m016:07Pittsburgh AirportPittsburgh Airport17:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 21/04/2026 16:07:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/04/2026 17:00:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 53m
-
Skyscanner1h 56m008:54Pittsburgh AirportPittsburgh Airport09:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 21/04/2026 08:54:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/04/2026 09:50:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 56m
-
American Airlines1h 58m006:12Pittsburgh AirportPittsburgh Airport07:10Chicago Midway AirportChicago Midway Airport0EconomyA Flight from American Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 21/04/2026 06:12:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 21/04/2026 07:10:00. 50 Economy ticket for £77 per person are available. Travel duration is 1h 58m
-
Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 21/04/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 21/04/2026 10:00:00. 50 Economy ticket for £45 per person are available. Travel duration is 10h 5m
-
FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 21/04/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 22/04/2026 06:10:00. 50 Economy ticket for £50 per person are available. Travel duration is 11h 25m
-
Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 21/04/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 21/04/2026 20:05:00. 50 Economy ticket for £44 per person are available. Travel duration is 12h 30m
Fastest Flights Tuesday
Fastest Buses Tuesday
-
United Airlines1h 46m010:49Pittsburgh AirportPittsburgh Airport11:35Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 22/04/2026 10:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 11:35:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m014:09Pittsburgh AirportPittsburgh Airport14:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 22/04/2026 14:09:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 14:55:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 46m
-
United Airlines1h 49m007:00Pittsburgh AirportPittsburgh Airport07:49Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 22/04/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 07:49:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 49m
-
Skyscanner1h 53m016:07Pittsburgh AirportPittsburgh Airport17:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 22/04/2026 16:07:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 17:00:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 53m
-
Skyscanner1h 56m008:54Pittsburgh AirportPittsburgh Airport09:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 22/04/2026 08:54:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 09:50:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 56m
-
Spirit Airlines13h 56m006:35Pittsburgh AirportPittsburgh Airport19:31Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 22/04/2026 06:35:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 22/04/2026 19:31:00. 50 Economy ticket for £119 per person are available. Travel duration is 13h 56m
-
Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 22/04/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 22/04/2026 10:00:00. 50 Economy ticket for £39 per person are available. Travel duration is 10h 5m
-
FlixBus10h 55m019:45PittsburghGrant Street Transportation Center05:40Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 22/04/2026 19:45:00 to 95th Red Line Station, Chicago (USA) arriving at 23/04/2026 05:40:00. 50 Economy ticket for £47 per person are available. Travel duration is 10h 55m
-
FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 22/04/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 23/04/2026 06:10:00. 50 Economy ticket for £43 per person are available. Travel duration is 11h 25m
-
Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 22/04/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 22/04/2026 20:05:00. 50 Economy ticket for £39 per person are available. Travel duration is 12h 30m
Fastest Flights Wednesday
Fastest Buses Wednesday
-
United Airlines1h 30m020:00Pittsburgh AirportPittsburgh Airport20:30Chicago Midway AirportChicago Midway Airport0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 23/04/2026 20:00:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 23/04/2026 20:30:00. 50 Economy ticket for £66 per person are available. Travel duration is 1h 30m
-
United Airlines1h 49m007:00Pittsburgh AirportPittsburgh Airport07:49Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 23/04/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/04/2026 07:49:00. 50 Economy ticket for £127 per person are available. Travel duration is 1h 49m
-
United Airlines1h 56m018:00Pittsburgh AirportPittsburgh Airport18:56Chicago Midway AirportChicago Midway Airport0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 23/04/2026 18:00:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 23/04/2026 18:56:00. 50 Economy ticket for £66 per person are available. Travel duration is 1h 56m
-
Skyscanner1h 56m008:54Pittsburgh AirportPittsburgh Airport09:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 23/04/2026 08:54:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/04/2026 09:50:00. 50 Economy ticket for £127 per person are available. Travel duration is 1h 56m
-
Breeze Airways7h 6m015:06Pittsburgh AirportPittsburgh Airport21:12Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Breeze Airways goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 23/04/2026 15:06:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/04/2026 21:12:00. 50 Economy ticket for £201 per person are available. Travel duration is 7h 6m
-
Spirit Airlines7h 9m018:15Pittsburgh AirportPittsburgh Airport00:24Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 23/04/2026 18:15:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 00:24:00. 50 Economy ticket for £83 per person are available. Travel duration is 7h 9m
-
Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 23/04/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 23/04/2026 10:00:00. 50 Economy ticket for £45 per person are available. Travel duration is 10h 5m
-
FlixBus10h 55m019:45PittsburghGrant Street Transportation Center05:40Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 23/04/2026 19:45:00 to 95th Red Line Station, Chicago (USA) arriving at 24/04/2026 05:40:00. 50 Economy ticket for £52 per person are available. Travel duration is 10h 55m
-
FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 23/04/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 06:10:00. 50 Economy ticket for £48 per person are available. Travel duration is 11h 25m
-
Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 23/04/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 23/04/2026 20:05:00. 50 Economy ticket for £43 per person are available. Travel duration is 12h 30m
-
Greyhound US14h 15m001:20PittsburghGrant Street Transportation Center14:35ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 23/04/2026 01:20:00 to Downtown Coach Station, Chicago (USA) arriving at 23/04/2026 14:35:00. 50 Economy ticket for £46 per person are available. Travel duration is 14h 15m
Fastest Flights Thursday
Fastest Buses Thursday
-
United Airlines1h 46m010:49Pittsburgh AirportPittsburgh Airport11:35Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 24/04/2026 10:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 11:35:00. 50 Economy ticket for £125 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m014:09Pittsburgh AirportPittsburgh Airport14:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 24/04/2026 14:09:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 14:55:00. 50 Economy ticket for £125 per person are available. Travel duration is 1h 46m
-
United Airlines1h 49m007:00Pittsburgh AirportPittsburgh Airport07:49Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 24/04/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 07:49:00. 50 Economy ticket for £125 per person are available. Travel duration is 1h 49m
-
United Airlines1h 53m016:07Pittsburgh AirportPittsburgh Airport17:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 24/04/2026 16:07:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 17:00:00. 50 Economy ticket for £125 per person are available. Travel duration is 1h 53m
-
United Airlines1h 56m008:54Pittsburgh AirportPittsburgh Airport09:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 24/04/2026 08:54:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 09:50:00. 50 Economy ticket for £125 per person are available. Travel duration is 1h 56m
-
Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 24/04/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 10:00:00. 50 Economy ticket for £47 per person are available. Travel duration is 10h 5m
-
FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 24/04/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 25/04/2026 06:10:00. 50 Economy ticket for £50 per person are available. Travel duration is 11h 25m
-
Greyhound US12h 15m008:50PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 24/04/2026 08:50:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 20:05:00. 50 Economy ticket for £60 per person are available. Travel duration is 12h 15m
-
Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 24/04/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 20:05:00. 50 Economy ticket for £49 per person are available. Travel duration is 12h 30m
Fastest Flights Friday
Fastest Buses Friday
-
United Airlines1h 49m007:00Pittsburgh AirportPittsburgh Airport07:49Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 25/04/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 07:49:00. 50 Economy ticket for £105 per person are available. Travel duration is 1h 49m
-
Skyscanner1h 56m008:54Pittsburgh AirportPittsburgh Airport09:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 25/04/2026 08:54:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 09:50:00. 50 Economy ticket for £105 per person are available. Travel duration is 1h 56m
-
Spirit Airlines7h 9m018:15Pittsburgh AirportPittsburgh Airport00:24Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 25/04/2026 18:15:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 00:24:00. 50 Economy ticket for £62 per person are available. Travel duration is 7h 9m
-
Frontier Airlines11h 23m012:44Pittsburgh AirportPittsburgh Airport23:07Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 25/04/2026 12:44:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 23:07:00. 50 Economy ticket for £83 per person are available. Travel duration is 11h 23m
-
Spirit Airlines13h 2m006:35Pittsburgh AirportPittsburgh Airport18:37Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 25/04/2026 06:35:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 25/04/2026 18:37:00. 50 Economy ticket for £118 per person are available. Travel duration is 13h 2m
-
JetBlue Airways16h 39m006:00Pittsburgh AirportPittsburgh Airport21:39Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from JetBlue Airways goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 25/04/2026 06:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 21:39:00. 50 Economy ticket for £183 per person are available. Travel duration is 16h 39m
-
Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 25/04/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 25/04/2026 10:00:00. 50 Economy ticket for £51 per person are available. Travel duration is 10h 5m
-
FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 25/04/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 26/04/2026 06:10:00. 50 Economy ticket for £51 per person are available. Travel duration is 11h 25m
-
Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 25/04/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 25/04/2026 20:05:00. 50 Economy ticket for £50 per person are available. Travel duration is 12h 30m
Fastest Flights Saturday
Fastest Buses Saturday
-
United Airlines1h 46m010:49Pittsburgh AirportPittsburgh Airport11:35Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 26/04/2026 10:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 11:35:00. 50 Economy ticket for £136 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m014:09Pittsburgh AirportPittsburgh Airport14:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 26/04/2026 14:09:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 14:55:00. 50 Economy ticket for £136 per person are available. Travel duration is 1h 46m
-
United Airlines1h 49m007:00Pittsburgh AirportPittsburgh Airport07:49Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 26/04/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 07:49:00. 50 Economy ticket for £136 per person are available. Travel duration is 1h 49m
-
Skyscanner1h 53m016:07Pittsburgh AirportPittsburgh Airport17:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 26/04/2026 16:07:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 17:00:00. 50 Economy ticket for £136 per person are available. Travel duration is 1h 53m
-
Skyscanner1h 56m008:54Pittsburgh AirportPittsburgh Airport09:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 26/04/2026 08:54:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 09:50:00. 50 Economy ticket for £136 per person are available. Travel duration is 1h 56m
-
Allegiant Air15h 22m006:30Pittsburgh AirportPittsburgh Airport20:52Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Allegiant Air goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 26/04/2026 06:30:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 26/04/2026 20:52:00. 50 Economy ticket for £126 per person are available. Travel duration is 15h 22m
-
Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 26/04/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 26/04/2026 10:00:00. 50 Economy ticket for £43 per person are available. Travel duration is 10h 5m
-
FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 26/04/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 27/04/2026 06:10:00. 50 Economy ticket for £47 per person are available. Travel duration is 11h 25m
-
Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 26/04/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 26/04/2026 20:05:00. 50 Economy ticket for £44 per person are available. Travel duration is 12h 30m
Fastest Flights Sunday
Fastest Buses Sunday
Here you will find all operators and timetables for a
Bus from Pittsburgh to Chicago
What are the most popular stations in Pittsburgh and Chicago?
In Pittsburgh, you will usually depart from Grant Street Transportation Center, Central Station or David L. Lawrence Convention Center, while in Chicago you will be arriving at California & 35th Street Coach Stop, Downtown Coach Station or 95th Red Line Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Chicago from Pittsburgh? With 13 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Pittsburgh and Chicago, you can pay as low as £39 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Chicago in just 1h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Pittsburgh and Chicago are Greyhound US, United Airlines and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Pittsburgh and Chicago is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Green Tree, PA or to Cicero, IL, and look at flights from Pittsburgh Airport, and landing at Chicago Midway Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Pittsburgh to Chicago?
The most popular companies between Pittsburgh and Chicago, are Greyhound US, United Airlines and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: United Airlines, Spirit Airlines, Skyscanner and 9 more.
All you need to know when you travel from Pittsburgh to Chicago
Check all information on comfort and services on all modes of transports from Pittsburgh to Chicago. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Pittsburgh to Chicago
How can I reach Chicago from Pittsburgh?
Every day, there are on average 13 connections between Flight and Bus, with which you can get to Chicago from Pittsburgh.
How far is Chicago from Pittsburgh?
The distance between Pittsburgh and Chicago is 659.2 km.
What is the most ecofriendly mode of transport between Pittsburgh and Chicago?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 18 kgs of CO2, a train 23 kgs, a car 112 kgs, and a flight 162 kgs.
What is the cheapest mode of transport from Pittsburgh to Chicago?
You can get to Chicago with just £39 by taking a Bus from Greyhound US.
What is the fastest way to get from Pittsburgh to Chicago?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Chicago in just 1h 30m with a Flight from United Airlines.
More routes to Pittsburgh and to Chicago
Looking for more options? Here you can see the most popular routes to Pittsburgh and to Chicago. Simply click on a connection, and you’ll find all the details about the route!
