What is the best way to travel from Pittsburgh to Chicago?
Looking for a trip? Check and compare all the available Flights and Buses to Chicago from Pittsburgh. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Chicago from Pittsburgh?
You can reach Chicago with just £41 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 05/11/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 05/11/2026 20:05:00. 50 Economy ticket for £42 per person are available. Travel duration is 12h 30m
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FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 05/11/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 06/11/2026 06:10:00. 50 Economy ticket for £42 per person are available. Travel duration is 11h 25m
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Greyhound US12h 15m008:50PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 05/11/2026 08:50:00 to Downtown Coach Station, Chicago (USA) arriving at 05/11/2026 20:05:00. 50 Economy ticket for £49 per person are available. Travel duration is 12h 15m
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JetBlue Airways1h 30m019:55Pittsburgh AirportPittsburgh Airport20:25Chicago Midway AirportChicago Midway Airport0EconomyA Flight from JetBlue Airways goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 05/11/2026 19:55:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 05/11/2026 20:25:00. 50 Economy ticket for £92 per person are available. Travel duration is 1h 30m
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JetBlue Airways7h 30m012:47Pittsburgh AirportPittsburgh Airport19:17Chicago Midway AirportChicago Midway Airport0EconomyA Flight from JetBlue Airways goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 05/11/2026 12:47:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 05/11/2026 19:17:00. 50 Economy ticket for £112 per person are available. Travel duration is 7h 30m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 06/11/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 06/11/2026 10:00:00. 50 Economy ticket for £42 per person are available. Travel duration is 10h 5m
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Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 06/11/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 06/11/2026 20:05:00. 50 Economy ticket for £42 per person are available. Travel duration is 12h 30m
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FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 06/11/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 07/11/2026 06:10:00. 50 Economy ticket for £42 per person are available. Travel duration is 11h 25m
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JetBlue Airways7h 30m012:47Pittsburgh AirportPittsburgh Airport19:17Chicago Midway AirportChicago Midway Airport0EconomyA Flight from JetBlue Airways goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 06/11/2026 12:47:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 06/11/2026 19:17:00. 50 Economy ticket for £112 per person are available. Travel duration is 7h 30m
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JetBlue Airways1h 35m016:00Pittsburgh AirportPittsburgh Airport16:35Chicago Midway AirportChicago Midway Airport0EconomyA Flight from JetBlue Airways goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 06/11/2026 16:00:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 06/11/2026 16:35:00. 50 Economy ticket for £119 per person are available. Travel duration is 1h 35m
Cheapest Buses Friday
Cheapest Flights Friday
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FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 07/11/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 08/11/2026 06:10:00. 50 Economy ticket for £41 per person are available. Travel duration is 11h 25m
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Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 07/11/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 07/11/2026 10:00:00. 50 Economy ticket for £42 per person are available. Travel duration is 10h 5m
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Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 07/11/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 07/11/2026 20:05:00. 50 Economy ticket for £42 per person are available. Travel duration is 12h 30m
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United Airlines1h 53m006:30Pittsburgh AirportPittsburgh Airport07:23Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 07/11/2026 06:30:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 07/11/2026 07:23:00. 50 Economy ticket for £51 per person are available. Travel duration is 1h 53m
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United Airlines1h 56m008:49Pittsburgh AirportPittsburgh Airport09:45Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 07/11/2026 08:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 07/11/2026 09:45:00. 50 Economy ticket for £51 per person are available. Travel duration is 1h 56m
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United Airlines1h 48m014:03Pittsburgh AirportPittsburgh Airport14:51Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 07/11/2026 14:03:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 07/11/2026 14:51:00. 50 Economy ticket for £51 per person are available. Travel duration is 1h 48m
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United Airlines1h 48m017:51Pittsburgh AirportPittsburgh Airport18:39Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 07/11/2026 17:51:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 07/11/2026 18:39:00. 50 Economy ticket for £51 per person are available. Travel duration is 1h 48m
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United Airlines1h 54m019:37Pittsburgh AirportPittsburgh Airport20:31Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 07/11/2026 19:37:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 07/11/2026 20:31:00. 50 Economy ticket for £51 per person are available. Travel duration is 1h 54m
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Allegiant Air1h 30m008:45Pittsburgh AirportPittsburgh Airport09:15Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Allegiant Air goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 07/11/2026 08:45:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 07/11/2026 09:15:00. 50 Economy ticket for £92 per person are available. Travel duration is 1h 30m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 08/11/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 08/11/2026 20:05:00. 50 Economy ticket for £43 per person are available. Travel duration is 12h 30m
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Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 08/11/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 08/11/2026 10:00:00. 50 Economy ticket for £44 per person are available. Travel duration is 10h 5m
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FlixBus12h 55m007:00PittsburghGrant Street Transportation Center18:55ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 08/11/2026 07:00:00 to Downtown Coach Station, Chicago (USA) arriving at 08/11/2026 18:55:00. 50 Economy ticket for £49 per person are available. Travel duration is 12h 55m
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FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 08/11/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 06:10:00. 50 Economy ticket for £49 per person are available. Travel duration is 11h 25m
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Greyhound US13h 0m001:25PittsburghGrant Street Transportation Center13:25ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 08/11/2026 01:25:00 to Downtown Coach Station, Chicago (USA) arriving at 08/11/2026 13:25:00. 50 Economy ticket for £50 per person are available. Travel duration is 13h 0m
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JetBlue Airways8h 42m006:00Pittsburgh AirportPittsburgh Airport13:42Chicago Midway AirportChicago Midway Airport0EconomyA Flight from JetBlue Airways goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 08/11/2026 06:00:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 08/11/2026 13:42:00. 50 Economy ticket for £122 per person are available. Travel duration is 8h 42m
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JetBlue Airways36h 17m006:30Pittsburgh AirportPittsburgh Airport17:47Chicago Midway AirportChicago Midway Airport0EconomyA Flight from JetBlue Airways goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 08/11/2026 06:30:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 09/11/2026 17:47:00. 50 Economy ticket for £127 per person are available. Travel duration is 36h 17m
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United Airlines1h 53m006:30Pittsburgh AirportPittsburgh Airport07:23Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 08/11/2026 06:30:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/11/2026 07:23:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 53m
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United Airlines1h 56m008:49Pittsburgh AirportPittsburgh Airport09:45Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 08/11/2026 08:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/11/2026 09:45:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 56m
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United Airlines1h 48m014:07Pittsburgh AirportPittsburgh Airport14:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 08/11/2026 14:07:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/11/2026 14:55:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 48m
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United Airlines1h 56m019:33Pittsburgh AirportPittsburgh Airport20:29Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 08/11/2026 19:33:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/11/2026 20:29:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 56m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 09/11/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 10:00:00. 50 Economy ticket for £46 per person are available. Travel duration is 10h 5m
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Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 09/11/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 20:05:00. 50 Economy ticket for £46 per person are available. Travel duration is 12h 30m
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FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 09/11/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 10/11/2026 06:10:00. 50 Economy ticket for £46 per person are available. Travel duration is 11h 25m
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FlixBus12h 55m007:00PittsburghGrant Street Transportation Center18:55ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 09/11/2026 07:00:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 18:55:00. 50 Economy ticket for £47 per person are available. Travel duration is 12h 55m
Cheapest Buses Monday
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Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 10/11/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 10/11/2026 10:00:00. 50 Economy ticket for £46 per person are available. Travel duration is 10h 5m
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Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 10/11/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 10/11/2026 20:05:00. 50 Economy ticket for £46 per person are available. Travel duration is 12h 30m
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Greyhound US12h 15m008:50PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 10/11/2026 08:50:00 to Downtown Coach Station, Chicago (USA) arriving at 10/11/2026 20:05:00. 50 Economy ticket for £56 per person are available. Travel duration is 12h 15m
Cheapest Buses Tuesday
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Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 11/11/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 11/11/2026 10:00:00. 50 Economy ticket for £46 per person are available. Travel duration is 10h 5m
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Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 11/11/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 11/11/2026 20:05:00. 50 Economy ticket for £46 per person are available. Travel duration is 12h 30m
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FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 11/11/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 12/11/2026 06:10:00. 50 Economy ticket for £46 per person are available. Travel duration is 11h 25m
Cheapest Buses Wednesday
What are the fastest trips from Pittsburgh to Chicago?
You can get to Chicago from Pittsburgh in just 1h 30m with a Flight from JetBlue Airways. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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JetBlue Airways1h 30m019:55Pittsburgh AirportPittsburgh Airport20:25Chicago Midway AirportChicago Midway Airport0EconomyA Flight from JetBlue Airways goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 05/11/2026 19:55:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 05/11/2026 20:25:00. 50 Economy ticket for £92 per person are available. Travel duration is 1h 30m
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JetBlue Airways7h 30m012:47Pittsburgh AirportPittsburgh Airport19:17Chicago Midway AirportChicago Midway Airport0EconomyA Flight from JetBlue Airways goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 05/11/2026 12:47:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 05/11/2026 19:17:00. 50 Economy ticket for £112 per person are available. Travel duration is 7h 30m
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FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 05/11/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 06/11/2026 06:10:00. 50 Economy ticket for £42 per person are available. Travel duration is 11h 25m
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Greyhound US12h 15m008:50PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 05/11/2026 08:50:00 to Downtown Coach Station, Chicago (USA) arriving at 05/11/2026 20:05:00. 50 Economy ticket for £49 per person are available. Travel duration is 12h 15m
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Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 05/11/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 05/11/2026 20:05:00. 50 Economy ticket for £42 per person are available. Travel duration is 12h 30m
Fastest Flights Thursday
Fastest Buses Thursday
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JetBlue Airways1h 35m016:00Pittsburgh AirportPittsburgh Airport16:35Chicago Midway AirportChicago Midway Airport0EconomyA Flight from JetBlue Airways goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 06/11/2026 16:00:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 06/11/2026 16:35:00. 50 Economy ticket for £119 per person are available. Travel duration is 1h 35m
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JetBlue Airways7h 30m012:47Pittsburgh AirportPittsburgh Airport19:17Chicago Midway AirportChicago Midway Airport0EconomyA Flight from JetBlue Airways goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 06/11/2026 12:47:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 06/11/2026 19:17:00. 50 Economy ticket for £112 per person are available. Travel duration is 7h 30m
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Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 06/11/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 06/11/2026 10:00:00. 50 Economy ticket for £42 per person are available. Travel duration is 10h 5m
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FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 06/11/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 07/11/2026 06:10:00. 50 Economy ticket for £42 per person are available. Travel duration is 11h 25m
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Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 06/11/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 06/11/2026 20:05:00. 50 Economy ticket for £42 per person are available. Travel duration is 12h 30m
Fastest Flights Friday
Fastest Buses Friday
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Allegiant Air1h 30m008:45Pittsburgh AirportPittsburgh Airport09:15Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Allegiant Air goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 07/11/2026 08:45:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 07/11/2026 09:15:00. 50 Economy ticket for £92 per person are available. Travel duration is 1h 30m
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Allegiant Air1h 48m017:51Pittsburgh AirportPittsburgh Airport18:39Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Allegiant Air goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 07/11/2026 17:51:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 07/11/2026 18:39:00. 50 Economy ticket for £92 per person are available. Travel duration is 1h 48m
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United Airlines1h 48m014:03Pittsburgh AirportPittsburgh Airport14:51Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 07/11/2026 14:03:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 07/11/2026 14:51:00. 50 Economy ticket for £51 per person are available. Travel duration is 1h 48m
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United Airlines1h 48m017:51Pittsburgh AirportPittsburgh Airport18:39Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 07/11/2026 17:51:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 07/11/2026 18:39:00. 50 Economy ticket for £51 per person are available. Travel duration is 1h 48m
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United Airlines1h 53m006:30Pittsburgh AirportPittsburgh Airport07:23Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 07/11/2026 06:30:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 07/11/2026 07:23:00. 50 Economy ticket for £51 per person are available. Travel duration is 1h 53m
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United Airlines1h 54m019:37Pittsburgh AirportPittsburgh Airport20:31Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 07/11/2026 19:37:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 07/11/2026 20:31:00. 50 Economy ticket for £51 per person are available. Travel duration is 1h 54m
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Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 07/11/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 07/11/2026 10:00:00. 50 Economy ticket for £42 per person are available. Travel duration is 10h 5m
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FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 07/11/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 08/11/2026 06:10:00. 50 Economy ticket for £41 per person are available. Travel duration is 11h 25m
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Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 07/11/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 07/11/2026 20:05:00. 50 Economy ticket for £42 per person are available. Travel duration is 12h 30m
Fastest Flights Saturday
Fastest Buses Saturday
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United Airlines1h 48m014:07Pittsburgh AirportPittsburgh Airport14:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 08/11/2026 14:07:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/11/2026 14:55:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 48m
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United Airlines1h 53m006:30Pittsburgh AirportPittsburgh Airport07:23Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 08/11/2026 06:30:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/11/2026 07:23:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 53m
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United Airlines1h 56m008:49Pittsburgh AirportPittsburgh Airport09:45Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 08/11/2026 08:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/11/2026 09:45:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 56m
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United Airlines1h 56m019:33Pittsburgh AirportPittsburgh Airport20:29Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 08/11/2026 19:33:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/11/2026 20:29:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 56m
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United Airlines1h 56m010:49Pittsburgh AirportPittsburgh Airport11:45Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 08/11/2026 10:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 08/11/2026 11:45:00. 50 Economy ticket for £208 per person are available. Travel duration is 1h 56m
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JetBlue Airways8h 42m006:00Pittsburgh AirportPittsburgh Airport13:42Chicago Midway AirportChicago Midway Airport0EconomyA Flight from JetBlue Airways goes from Pittsburgh Airport, Pittsburgh Airport (USA) at 08/11/2026 06:00:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 08/11/2026 13:42:00. 50 Economy ticket for £122 per person are available. Travel duration is 8h 42m
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Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 08/11/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 08/11/2026 10:00:00. 50 Economy ticket for £44 per person are available. Travel duration is 10h 5m
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FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 08/11/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 06:10:00. 50 Economy ticket for £49 per person are available. Travel duration is 11h 25m
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Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 08/11/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 08/11/2026 20:05:00. 50 Economy ticket for £43 per person are available. Travel duration is 12h 30m
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FlixBus12h 55m007:00PittsburghGrant Street Transportation Center18:55ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 08/11/2026 07:00:00 to Downtown Coach Station, Chicago (USA) arriving at 08/11/2026 18:55:00. 50 Economy ticket for £49 per person are available. Travel duration is 12h 55m
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Greyhound US13h 0m001:25PittsburghGrant Street Transportation Center13:25ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 08/11/2026 01:25:00 to Downtown Coach Station, Chicago (USA) arriving at 08/11/2026 13:25:00. 50 Economy ticket for £50 per person are available. Travel duration is 13h 0m
Fastest Flights Sunday
Fastest Buses Sunday
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Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 09/11/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 10:00:00. 50 Economy ticket for £46 per person are available. Travel duration is 10h 5m
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FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 09/11/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 10/11/2026 06:10:00. 50 Economy ticket for £46 per person are available. Travel duration is 11h 25m
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Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 09/11/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 20:05:00. 50 Economy ticket for £46 per person are available. Travel duration is 12h 30m
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FlixBus12h 55m007:00PittsburghGrant Street Transportation Center18:55ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 09/11/2026 07:00:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 18:55:00. 50 Economy ticket for £47 per person are available. Travel duration is 12h 55m
Fastest Buses Monday
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Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 10/11/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 10/11/2026 10:00:00. 50 Economy ticket for £46 per person are available. Travel duration is 10h 5m
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Greyhound US12h 15m008:50PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 10/11/2026 08:50:00 to Downtown Coach Station, Chicago (USA) arriving at 10/11/2026 20:05:00. 50 Economy ticket for £56 per person are available. Travel duration is 12h 15m
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Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 10/11/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 10/11/2026 20:05:00. 50 Economy ticket for £46 per person are available. Travel duration is 12h 30m
Fastest Buses Tuesday
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Greyhound US10h 5m000:55PittsburghGrant Street Transportation Center10:00ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 11/11/2026 00:55:00 to Downtown Coach Station, Chicago (USA) arriving at 11/11/2026 10:00:00. 50 Economy ticket for £46 per person are available. Travel duration is 10h 5m
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FlixBus11h 25m019:45PittsburghGrant Street Transportation Center06:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Grant Street Transportation Center, Pittsburgh (USA) at 11/11/2026 19:45:00 to Downtown Coach Station, Chicago (USA) arriving at 12/11/2026 06:10:00. 50 Economy ticket for £46 per person are available. Travel duration is 11h 25m
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Greyhound US12h 30m008:35PittsburghGrant Street Transportation Center20:05ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Grant Street Transportation Center, Pittsburgh (USA) at 11/11/2026 08:35:00 to Downtown Coach Station, Chicago (USA) arriving at 11/11/2026 20:05:00. 50 Economy ticket for £46 per person are available. Travel duration is 12h 30m
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Pittsburgh to Chicago
What are the most popular stations in Pittsburgh and Chicago?
In Pittsburgh, you will usually depart from Grant Street Transportation Center, David L. Lawrence Convention Center or Central Station, while in Chicago you will be arriving at California & 35th Street Coach Stop, Downtown Coach Station or 95th Red Line Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Chicago from Pittsburgh? With 7 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Pittsburgh and Chicago, you can pay as low as £41 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from JetBlue Airways: you will get to Chicago in just 1h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Pittsburgh and Chicago are Greyhound US, FlixBus and United Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Pittsburgh and Chicago is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Green Tree, PA or to Cicero, IL, and look at flights from Pittsburgh Airport, and landing at Chicago Midway Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Pittsburgh to Chicago?
The most popular companies between Pittsburgh and Chicago, are Greyhound US, FlixBus and United Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: United Airlines, JetBlue Airways and Allegiant Air
All you need to know when you travel from Pittsburgh to Chicago
Check all information on comfort and services on all modes of transports from Pittsburgh to Chicago. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Pittsburgh to Chicago
How can I reach Chicago from Pittsburgh?
Every day, there are on average 7 connections between Flight and Bus, with which you can get to Chicago from Pittsburgh.
How far is Chicago from Pittsburgh?
The distance between Pittsburgh and Chicago is 659.2 km.
What is the most ecofriendly mode of transport between Pittsburgh and Chicago?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 18 kgs of CO2, a train 23 kgs, a car 112 kgs, and a flight 162 kgs.
What is the cheapest mode of transport from Pittsburgh to Chicago?
You can get to Chicago with just £41 by taking a Bus from FlixBus.
What is the fastest way to get from Pittsburgh to Chicago?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Chicago in just 1h 30m with a Flight from JetBlue Airways.
More routes to Pittsburgh and to Chicago
Looking for more options? Here you can see the most popular routes to Pittsburgh and to Chicago. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Pittsburgh
- Baltimore, MD to Pittsburgh
- New York to Pittsburgh
- Washington, DC to Pittsburgh
- Trips to Chicago
- Aguascalientes to Chicago
- Atlanta, GA to Chicago
- Cincinnati to Chicago
- Ciudad Juárez to Chicago
- Cleveland to Chicago
- Columbus, OH to Chicago
- Dallas to Chicago
- Durango, DG to Chicago
- El Paso, TX to Chicago
- Guadalajara, JC to Chicago
- Houston to Chicago
- Los Angeles to Chicago
- McAllen, TX to Chicago
- Memphis to Chicago
- Mexico City to Chicago
- Nashville to Chicago
- New York to Chicago
- Newark to Chicago
- San Antonio, TX to Chicago
- San Luis Potosí to Chicago
- Tampa to Chicago
- Toronto, ON to Chicago
