Bus and Coach from San Antonio, TX to Chicago: Compare all prices

Compare all timetables for the bus from San Antonio, TX to Chicago

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to Chicago from various bus operators like FlixBus, Greyhound Lines Mexico or Greyhound US for the next days.

today

£153

tomorrow

Sunday

£153

Monday

Tuesday

£141

Wednesday

£145

Thursday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	30h 55m	21:15	San Antonio, TX	Coach Station	04:10	Chicago	Downtown Coach Station	Economy	£153	A Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 21:15:00 to Downtown Coach Station, Chicago (USA) arriving at 21/12/2025 04:10:00. 50 Economy ticket for £153 per person are available. Travel duration is 30h 55m
Greyhound US	31h 35m	12:35	San Antonio, TX	Coach Station	20:10	Chicago	Downtown Coach Station	Economy	£173	A Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 12:35:00 to Downtown Coach Station, Chicago (USA) arriving at 20/12/2025 20:10:00. 50 Economy ticket for £173 per person are available. Travel duration is 31h 35m
FlixBus	32h 5m	21:15	San Antonio, TX	Coach Station	05:20	Chicago	95th Red Line Station	Economy	£190	A Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 21:15:00 to 95th Red Line Station, Chicago (USA) arriving at 21/12/2025 05:20:00. 50 Economy ticket for £190 per person are available. Travel duration is 32h 5m
Greyhound US	34h 25m	12:35	San Antonio, TX	Coach Station	23:00	Chicago	95th Red Line Station	Economy	£205	A Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 20/12/2025 23:00:00. 50 Economy ticket for £205 per person are available. Travel duration is 34h 25m
FlixBus	34h 45m	21:15	San Antonio, TX	Coach Station	08:00	Chicago	Union Station	Economy	£236	A Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 19/12/2025 21:15:00 to Union Station, Chicago (USA) arriving at 21/12/2025 08:00:00. 50 Economy ticket for £236 per person are available. Travel duration is 34h 45m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	31h 35m	12:35	San Antonio, TX	Coach Station	20:10	Chicago	Downtown Coach Station	Economy	£153	A Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 21/12/2025 12:35:00 to Downtown Coach Station, Chicago (USA) arriving at 22/12/2025 20:10:00. 50 Economy ticket for £153 per person are available. Travel duration is 31h 35m
FlixBus	33h 0m	07:30	San Antonio, TX	Coach Station	16:30	Chicago	Downtown Coach Station	Economy	£158	A Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 21/12/2025 07:30:00 to Downtown Coach Station, Chicago (USA) arriving at 22/12/2025 16:30:00. 50 Economy ticket for £158 per person are available. Travel duration is 33h 0m
FlixBus	32h 45m	07:45	San Antonio, TX	Pearl District	16:30	Chicago	Downtown Coach Station	Economy	£158	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 21/12/2025 07:45:00 to Downtown Coach Station, Chicago (USA) arriving at 22/12/2025 16:30:00. 50 Economy ticket for £158 per person are available. Travel duration is 32h 45m
Greyhound Lines Mexico	33h 10m	06:05	San Antonio, TX	Coach Station	15:15	Chicago	Downtown Coach Station	Economy	£167	A Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 21/12/2025 06:05:00 to Downtown Coach Station, Chicago (USA) arriving at 22/12/2025 15:15:00. 50 Economy ticket for £167 per person are available. Travel duration is 33h 10m
Greyhound US	34h 25m	12:35	San Antonio, TX	Coach Station	23:00	Chicago	95th Red Line Station	Economy	£175	A Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 21/12/2025 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 22/12/2025 23:00:00. 50 Economy ticket for £175 per person are available. Travel duration is 34h 25m

Did you know that if you travel from San Antonio, TX to Chicago via Dallas, you can save more than £17? You can find the corresponding connections below.
- Busbud
  
  34h 50m
  
  0
  
  17:20
  
  San Antonio, TX
  Pearl District
  
  23:05
  
  Dallas
  Downtown
  
  0
  
  Economy
  
  £37
  
  A Bus from Busbud goes from Pearl District, San Antonio, TX (USA) at 21/12/2025 17:20:00 to Downtown, Dallas (USA) arriving at 21/12/2025 23:05:00. 50 Economy ticket for £37 per person are available. Travel duration is 5h 45m
- Busbud
  
  20h 55m
  
  0
  
  07:15
  
  Dallas
  Coach Station
  
  04:10
  
  Chicago
  Downtown Coach Station
  
  0
  
  Economy
  
  £99
  
  A Bus from Busbud goes from Coach Station, Dallas (USA) at 22/12/2025 07:15:00 to Downtown Coach Station, Chicago (USA) arriving at 23/12/2025 04:10:00. 50 Economy ticket for £99 per person are available. Travel duration is 20h 55m
Travel time is 3h 15m longer, but you will save £17

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound Lines Mexico	36h 45m	19:15	San Antonio, TX	Coach Station	08:00	Chicago	Union Station	Economy	£141	A Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 23/12/2025 19:15:00 to Union Station, Chicago (USA) arriving at 25/12/2025 08:00:00. 50 Economy ticket for £141 per person are available. Travel duration is 36h 45m
Greyhound Lines Mexico	32h 55m	19:15	San Antonio, TX	Coach Station	04:10	Chicago	Downtown Coach Station	Economy	£141	A Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 23/12/2025 19:15:00 to Downtown Coach Station, Chicago (USA) arriving at 25/12/2025 04:10:00. 50 Economy ticket for £141 per person are available. Travel duration is 32h 55m
Greyhound US	31h 35m	12:35	San Antonio, TX	Coach Station	20:10	Chicago	Downtown Coach Station	Economy	£142	A Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 23/12/2025 12:35:00 to Downtown Coach Station, Chicago (USA) arriving at 24/12/2025 20:10:00. 50 Economy ticket for £142 per person are available. Travel duration is 31h 35m
Greyhound US	34h 25m	12:35	San Antonio, TX	Coach Station	23:00	Chicago	95th Red Line Station	Economy	£160	A Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 23/12/2025 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 24/12/2025 23:00:00. 50 Economy ticket for £160 per person are available. Travel duration is 34h 25m
Greyhound Lines Mexico	34h 5m	19:15	San Antonio, TX	Coach Station	05:20	Chicago	95th Red Line Station	Economy	£163	A Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 23/12/2025 19:15:00 to 95th Red Line Station, Chicago (USA) arriving at 25/12/2025 05:20:00. 50 Economy ticket for £163 per person are available. Travel duration is 34h 5m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	31h 35m	12:35	San Antonio, TX	Coach Station	20:10	Chicago	Downtown Coach Station	Economy	£145	A Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 24/12/2025 12:35:00 to Downtown Coach Station, Chicago (USA) arriving at 25/12/2025 20:10:00. 50 Economy ticket for £145 per person are available. Travel duration is 31h 35m
FlixBus	30h 55m	21:15	San Antonio, TX	Coach Station	04:10	Chicago	Downtown Coach Station	Economy	£146	A Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 24/12/2025 21:15:00 to Downtown Coach Station, Chicago (USA) arriving at 26/12/2025 04:10:00. 50 Economy ticket for £146 per person are available. Travel duration is 30h 55m
Greyhound Lines Mexico	30h 30m	01:30	San Antonio, TX	Coach Station	08:00	Chicago	Union Station	Economy	£148	A Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 24/12/2025 01:30:00 to Union Station, Chicago (USA) arriving at 25/12/2025 08:00:00. 50 Economy ticket for £148 per person are available. Travel duration is 30h 30m
FlixBus	51h 45m	07:45	San Antonio, TX	Pearl District	11:30	Chicago	Downtown Coach Station	Economy	£148	A Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 24/12/2025 07:45:00 to Downtown Coach Station, Chicago (USA) arriving at 26/12/2025 11:30:00. 50 Economy ticket for £148 per person are available. Travel duration is 51h 45m
Greyhound Lines Mexico	26h 40m	01:30	San Antonio, TX	Coach Station	04:10	Chicago	Downtown Coach Station	Economy	£150	A Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 24/12/2025 01:30:00 to Downtown Coach Station, Chicago (USA) arriving at 25/12/2025 04:10:00. 50 Economy ticket for £150 per person are available. Travel duration is 26h 40m

Best Price Offer: The price for the cheapest coach from San Antonio, TX to Chicago is £104 on 04/01/2026. Flexible travellers save on ticket prices.

Frequency of bus connections between San Antonio, TX and Chicago

See here how frequent the connections between San Antonio, TX and Chicago are, during different times and days of the week.

Sunday is the busiest day, with more than 14 daily coaches from San Antonio, TX to Chicago. Friday has instead the fewest connections, with only 5 daily coaches between San Antonio, TX and Chicago.

The busiest time of the day is the Evening, with 11 coaches from San Antonio, TX to Chicago, while Afternoon sees the fewest connections between San Antonio, TX and Chicago, with 7 offers.

Facts about coaches from San Antonio, TX to Chicago

Compare all providers like FlixBus, Greyhound Lines Mexico and Greyhound US that travel 8 times every day by bus from San Antonio, TX to Chicago in one click! Book your bus ticket from San Antonio, TX to Chicago starting from £104!

Cheapest Bus	£104
Fastest Bus	26h 40m
Earliest Coach	12:35
Latest Coach	21:15
Daily Bus Connections	8 Ø
Distance	1,692.8 km
Coach Companies	FlixBus, Greyhound Lines Mexico and Greyhound US

Cheapest coach connections from San Antonio, TX to Chicago

Every day, 8 buses from 3 coach companies leave San Antonio, TX for Chicago: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 19/12/2025 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 15/12

Tuesday 16/12

Wednesday 17/12

Thursday 18/12

Friday 19/12

£153

Saturday 20/12

Sunday 21/12

£175

Monday 22/12

Tuesday 23/12

£141

Wednesday 24/12

£145

Thursday 25/12

Friday 26/12

£165

Saturday 27/12

Sunday 28/12

Monday 29/12

Tuesday 30/12

Wednesday 31/12

Thursday 01/01

Friday 02/01

Saturday 03/01

Sunday 04/01

£104

Monday 05/01

Tuesday 06/01

Wednesday 07/01

Thursday 08/01

Friday 09/01

Saturday 10/01

Sunday 11/01

The cheapest time to travel from San Antonio, TX to Chicago

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to Chicago, for the next 30 days.

With a price starting from £104, Sunday is the cheapest day for a coach from San Antonio, TX to Chicago. Friday instead is the most expensive day with prices starting from £153.

Night is the cheapest day time for bus tickets from San Antonio, TX to Chicago, with £104. Morning is the most expensive time of the day with prices starting from £148.

How to save money travelling from San Antonio, TX to Chicago

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to Chicago in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to Chicago, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from San Antonio, TX to Chicago are also emptier.

All bus stations and stops in San Antonio, TX and Chicago

The map below shows you where to find all the bus stations in San Antonio, TX and Chicago.

Coach Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

W. Southcross & Buffalo Bus Stop

Commerce & Bowie Bus Stop

95th Red Line Station

W. 95th St 14

Downtown Coach Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from San Antonio, TX to Chicago? Compare all modes of transports from San Antonio, TX to Chicago.

Service and Comfort on the bus from San Antonio, TX to Chicago

Want to know which seat classes are available on the coaches from San Antonio, TX to Chicago? Or which bus companies serve the route San Antonio, TX to Chicago? Below you will find answers to your questions.

FAQs about the San Antonio, TX to Chicago bus

How much does a San Antonio, TX - Chicago coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the San Antonio, TX - Chicago bus trip is available from £104 and takes 32h 55m. Compare offers and save money!

How much could I save by comparing buses from San Antonio, TX to Chicago?

The connection San Antonio, TX to Chicago is offered by 3 companies with ticket prices ranging from £104 to £236. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the San Antonio, TX - Chicago route on average every day?

Each day, the bus route from San Antonio, TX to Chicago is offered by roughly 8 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Chicago from San Antonio, TX take?

The quickest coach from San Antonio, TX to Chicago is provided by Greyhound Lines Mexico and takes 26h 40m. Coach tickets for this connection cost £197. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from San Antonio, TX to Chicago?

The earliest bus to Chicago departs from San Antonio, TX at 12:35. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from San Antonio, TX to Chicago?

The latest bus to Chicago departs from San Antonio, TX at 21:15. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the San Antonio, TX - Chicago route?

Passengers looking to travel from San Antonio, TX to Chicago can travel with FlixBus, Greyhound Lines Mexico and Greyhound US. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between San Antonio, TX and Chicago?

You can check all the direct connections between San Antonio, TX and Chicago by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound Lines Mexico and Greyhound US.

What can I take with me on the bus to Chicago from San Antonio, TX?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the San Antonio, TX Chicago bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX Chicago bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to Chicago on your planned travel date.

How does CheckMyBus find the best bus deals from San Antonio, TX to Chicago?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 8 daily trips between San Antonio, TX and Chicago. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Antonio, TX to Chicago?

Prices and availability for 8 trips between San Antonio, TX and Chicago change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Antonio, TX to Chicago

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to Chicago

Here’s an overview of the most popular bus routes to San Antonio, TX and to Chicago. Simply click on the connection of your choice, and you will find all the details about your bus route!