Bus and Coach from Mainz to Brussels: Compare all prices

Compare all timetables for the bus from Mainz to Brussels

Here is a selection of the cheapest bus trips from the schedule from Mainz to Brussels from various bus operators like FlixBus for the next days.

today

tomorrow

Monday

Tuesday

Wednesday

£21

Thursday

Friday

£19

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	7h 30m	01:00	Mainz	Central Station	08:30	Brussels	North Station	Economy	£21	A Bus from FlixBus goes from Central Station, Mainz (Germany) at 25/03/2026 01:00:00 to North Station, Brussels (Belgium) arriving at 25/03/2026 08:30:00. 50 Economy ticket for £21 per person are available. Travel duration is 7h 30m
FlixBus	8h 55m	10:30	Mainz	Central Station	19:25	Brussels	North Station	Economy	£21	A Bus from FlixBus goes from Central Station, Mainz (Germany) at 25/03/2026 10:30:00 to North Station, Brussels (Belgium) arriving at 25/03/2026 19:25:00. 50 Economy ticket for £21 per person are available. Travel duration is 8h 55m
FlixBus	9h 50m	22:40	Mainz	Central Station	08:30	Brussels	North Station	Economy	£21	A Bus from FlixBus goes from Central Station, Mainz (Germany) at 25/03/2026 22:40:00 to North Station, Brussels (Belgium) arriving at 26/03/2026 08:30:00. 50 Economy ticket for £21 per person are available. Travel duration is 9h 50m

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	5h 45m	12:20	Mainz	Central Station	18:05	Brussels	North Station		Economy	£19	A Bus from FlixBus goes from Central Station, Mainz (Germany) at 27/03/2026 12:20:00 to North Station, Brussels (Belgium) arriving at 27/03/2026 18:05:00. 50 Economy ticket for £19 per person are available. Travel duration is 5h 45m
	FlixBus	7h 30m	01:00	Mainz	Central Station	08:30	Brussels	North Station		Economy	£24	A Bus from FlixBus goes from Central Station, Mainz (Germany) at 27/03/2026 01:00:00 to North Station, Brussels (Belgium) arriving at 27/03/2026 08:30:00. 50 Economy ticket for £24 per person are available. Travel duration is 7h 30m

Best Price Offer: The price for the cheapest coach from Mainz to Brussels is £19 on 27/03/2026. Flexible travellers save on ticket prices.

Frequency of bus connections between Mainz and Brussels

See here how frequent the connections between Mainz and Brussels are, during different times and days of the week.

Wednesday is the busiest day, with more than 3 daily coaches from Mainz to Brussels. Friday has instead the fewest connections, with only 2 daily coaches between Mainz and Brussels.

The busiest time of the day is the Night, with 2 coaches from Mainz to Brussels, while Morning sees the fewest connections between Mainz and Brussels, with 1 offers.

Facts about coaches from Mainz to Brussels

Compare all providers like FlixBus that travel 2 times every day by bus from Mainz to Brussels in one click! Book your bus ticket from Mainz to Brussels starting from £19!

Cheapest Bus	£19
Fastest Bus	5h 45m
Earliest Coach	01:00
Latest Coach	12:20
Daily Bus Connections	2 Ø
Distance	291.9 km
Coach Companies	FlixBus

Cheapest coach connections from Mainz to Brussels

Every day, 2 buses from 1 coach companies leave Mainz for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 21/03/2026 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 16/03

Tuesday 17/03

Wednesday 18/03

Thursday 19/03

Friday 20/03

Saturday 21/03

Sunday 22/03

Monday 23/03

Tuesday 24/03

Wednesday 25/03

£21

Thursday 26/03

Friday 27/03

£19

Saturday 28/03

Sunday 29/03

£23

Monday 30/03

Tuesday 31/03

Wednesday 01/04

£22

Thursday 02/04

£28

Friday 03/04

Saturday 04/04

£28

Sunday 05/04

Monday 06/04

£32

Tuesday 07/04

Wednesday 08/04

£23

Thursday 09/04

£21

Friday 10/04

Saturday 11/04

Sunday 12/04

The cheapest time to travel from Mainz to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Mainz to Brussels, for the next 30 days.

With a price starting from £17, Wednesday is the cheapest day for a coach from Mainz to Brussels. Friday instead is the most expensive day with prices starting from £19.

Night is the cheapest day time for bus tickets from Mainz to Brussels, with £17. Morning is the most expensive time of the day with prices starting from £20.

How to save money travelling from Mainz to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mainz to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mainz to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Mainz to Brussels are also emptier.

All bus stations and stops in Mainz and Brussels

The map below shows you where to find all the bus stations in Mainz and Brussels.

Central Bus Station

Mombacher Str

Midi Bus Station

Avenue Fonsny 1

North Station

Rue du Progrès 80

Congrès

Boulevard Pachéco 7

Central Station

City Tours

Rue du Marché Aux Herbes 82

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mainz to Brussels? Compare all modes of transports from Mainz to Brussels.

Service and Comfort on the bus from Mainz to Brussels

Want to know which seat classes are available on the coaches from Mainz to Brussels? Or which bus companies serve the route Mainz to Brussels? Below you will find answers to your questions.

FAQs about the Mainz to Brussels bus

How much does a Mainz - Brussels coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Mainz - Brussels bus trip is available from £19 and takes 5h 45m. Compare offers and save money!

How much could I save by comparing buses from Mainz to Brussels?

The connection Mainz to Brussels is offered by 1 companies with ticket prices ranging from £19 to £24. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Mainz - Brussels route on average every day?

Each day, the bus route from Mainz to Brussels is offered by roughly 2 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Brussels from Mainz take?

The quickest coach from Mainz to Brussels is provided by FlixBus and takes 5h 45m. Coach tickets for this connection cost £19. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Mainz to Brussels?

The earliest bus to Brussels departs from Mainz at 01:00. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Mainz to Brussels?

The latest bus to Brussels departs from Mainz at 12:20. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Mainz - Brussels route?

Passengers looking to travel from Mainz to Brussels can travel with FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Mainz and Brussels?

You can check all the direct connections between Mainz and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the bus to Brussels from Mainz?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Mainz Brussels bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Mainz Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mainz to Brussels on your planned travel date.

How does CheckMyBus find the best bus deals from Mainz to Brussels?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Mainz and Brussels. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Mainz to Brussels?

Prices and availability for 2 trips between Mainz and Brussels change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Mainz to Brussels

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mainz and to Brussels

Here’s an overview of the most popular bus routes to Mainz and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!