Bus and Coach from Madrid to Brussels: Compare all prices

Compare all timetables for the bus from Madrid to Brussels

Here is a selection of the cheapest bus trips from the schedule from Madrid to Brussels from various bus operators like FlixBus or BlaBlaCar Bus for the next days.

today

£44

tomorrow

Thursday

£49

Friday

£51

Saturday

£55

Sunday

£42

Monday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 10m	16:40	Madrid	Sur Bus Station	15:50	Brussels	Midi Bus Station	Economy	£44	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 09/12/2025 16:40:00 to Midi Bus Station, Brussels (Belgium) arriving at 10/12/2025 15:50:00. 50 Economy ticket for £44 per person are available. Travel duration is 23h 10m
FlixBus	24h 5m	15:45	Madrid	Sur Bus Station	15:50	Brussels	Midi Bus Station	Economy	£45	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 09/12/2025 15:45:00 to Midi Bus Station, Brussels (Belgium) arriving at 10/12/2025 15:50:00. 50 Economy ticket for £45 per person are available. Travel duration is 24h 5m
FlixBus	24h 30m	15:45	Madrid	Sur Bus Station	16:15	Brussels	North Station	Economy	£45	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 09/12/2025 15:45:00 to North Station, Brussels (Belgium) arriving at 10/12/2025 16:15:00. 50 Economy ticket for £45 per person are available. Travel duration is 24h 30m
FlixBus	22h 30m	16:40	Madrid	Sur Bus Station	15:10	Brussels	North Station	Economy	£45	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 09/12/2025 16:40:00 to North Station, Brussels (Belgium) arriving at 10/12/2025 15:10:00. 50 Economy ticket for £45 per person are available. Travel duration is 22h 30m
FlixBus	24h 5m	20:25	Madrid	Sur Bus Station	20:30	Brussels	North Station	Economy	£45	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 09/12/2025 20:25:00 to North Station, Brussels (Belgium) arriving at 10/12/2025 20:30:00. 50 Economy ticket for £45 per person are available. Travel duration is 24h 5m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	22h 55m	16:40	Madrid	Sur Bus Station	15:35	Brussels	Midi Bus Station	Economy	£49	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 11/12/2025 16:40:00 to Midi Bus Station, Brussels (Belgium) arriving at 12/12/2025 15:35:00. 50 Economy ticket for £49 per person are available. Travel duration is 22h 55m
FlixBus	21h 50m	20:25	Madrid	Sur Bus Station	18:15	Brussels	North Station	Economy	£49	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 11/12/2025 20:25:00 to North Station, Brussels (Belgium) arriving at 12/12/2025 18:15:00. 50 Economy ticket for £49 per person are available. Travel duration is 21h 50m
FlixBus	23h 10m	16:40	Madrid	Sur Bus Station	15:50	Brussels	Midi Bus Station	Economy	£50	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 11/12/2025 16:40:00 to Midi Bus Station, Brussels (Belgium) arriving at 12/12/2025 15:50:00. 50 Economy ticket for £50 per person are available. Travel duration is 23h 10m
FlixBus	23h 10m	14:50	Madrid	Sur Bus Station	14:00	Brussels	North Station	Economy	£50	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 11/12/2025 14:50:00 to North Station, Brussels (Belgium) arriving at 12/12/2025 14:00:00. 50 Economy ticket for £50 per person are available. Travel duration is 23h 10m
FlixBus	21h 55m	14:50	Madrid	Sur Bus Station	12:45	Brussels	Midi Bus Station	Economy	£51	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 11/12/2025 14:50:00 to Midi Bus Station, Brussels (Belgium) arriving at 12/12/2025 12:45:00. 50 Economy ticket for £51 per person are available. Travel duration is 21h 55m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	21h 55m	14:50	Madrid	Sur Bus Station	12:45	Brussels	North Station	Economy	£51	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/12/2025 14:50:00 to North Station, Brussels (Belgium) arriving at 13/12/2025 12:45:00. 50 Economy ticket for £51 per person are available. Travel duration is 21h 55m
FlixBus	22h 55m	16:40	Madrid	Sur Bus Station	15:35	Brussels	North Station	Economy	£51	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/12/2025 16:40:00 to North Station, Brussels (Belgium) arriving at 13/12/2025 15:35:00. 50 Economy ticket for £51 per person are available. Travel duration is 22h 55m
FlixBus	21h 50m	20:25	Madrid	Sur Bus Station	18:15	Brussels	North Station	Economy	£51	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/12/2025 20:25:00 to North Station, Brussels (Belgium) arriving at 13/12/2025 18:15:00. 50 Economy ticket for £51 per person are available. Travel duration is 21h 50m
FlixBus	21h 30m	20:25	Madrid	Sur Bus Station	17:55	Brussels	Midi Bus Station	Economy	£51	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/12/2025 20:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 13/12/2025 17:55:00. 50 Economy ticket for £51 per person are available. Travel duration is 21h 30m
FlixBus	26h 10m	20:50	Madrid	Sur Bus Station	23:00	Brussels	North Station	Economy	£57	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 12/12/2025 20:50:00 to North Station, Brussels (Belgium) arriving at 13/12/2025 23:00:00. 50 Economy ticket for £57 per person are available. Travel duration is 26h 10m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	21h 55m	14:50	Madrid	Sur Bus Station	12:45	Brussels	North Station	Economy	£55	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 13/12/2025 14:50:00 to North Station, Brussels (Belgium) arriving at 14/12/2025 12:45:00. 50 Economy ticket for £55 per person are available. Travel duration is 21h 55m
FlixBus	24h 30m	15:45	Madrid	Sur Bus Station	16:15	Brussels	North Station	Economy	£55	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 13/12/2025 15:45:00 to North Station, Brussels (Belgium) arriving at 14/12/2025 16:15:00. 50 Economy ticket for £55 per person are available. Travel duration is 24h 30m
FlixBus	22h 55m	16:40	Madrid	Sur Bus Station	15:35	Brussels	North Station	Economy	£55	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 13/12/2025 16:40:00 to North Station, Brussels (Belgium) arriving at 14/12/2025 15:35:00. 50 Economy ticket for £55 per person are available. Travel duration is 22h 55m
FlixBus	24h 5m	15:45	Madrid	Sur Bus Station	15:50	Brussels	Midi Bus Station	Economy	£55	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 13/12/2025 15:45:00 to Midi Bus Station, Brussels (Belgium) arriving at 14/12/2025 15:50:00. 50 Economy ticket for £55 per person are available. Travel duration is 24h 5m
FlixBus	23h 10m	16:40	Madrid	Sur Bus Station	15:50	Brussels	Midi Bus Station	Economy	£55	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 13/12/2025 16:40:00 to Midi Bus Station, Brussels (Belgium) arriving at 14/12/2025 15:50:00. 50 Economy ticket for £55 per person are available. Travel duration is 23h 10m

Did you know that if you travel from Madrid to Brussels via Bordeaux, you can save more than £10? You can find the corresponding connections below.
- Distribusion
  
  27h 30m
  
  0
  
  10:00
  
  Madrid
  Sur Bus Station
  
  22:30
  
  Bordeaux
  Saint Jean Train Station
  
  0
  
  Basic
  
  £18
  
  A Bus from Distribusion goes from Sur Bus Station, Madrid (Spain) at 14/12/2025 10:00:00 to Saint Jean Train Station, Bordeaux (France) arriving at 14/12/2025 22:30:00. 50 Basic ticket for £18 per person are available. Travel duration is 12h 30m
- BlaBlaCar Bus
  
  13h 25m
  
  0
  
  00:05
  
  Bordeaux
  Saint Jean Train Station
  
  13:30
  
  Brussels
  Midi Bus Station
  
  0
  
  Economy
  
  £27
  
  A Bus from BlaBlaCar Bus goes from Saint Jean Train Station, Bordeaux (France) at 15/12/2025 00:05:00 to Midi Bus Station, Brussels (Belgium) arriving at 15/12/2025 13:30:00. 50 Economy ticket for £27 per person are available. Travel duration is 13h 25m
Travel time is 5h 35m longer, but you will save £10

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
BlaBlaCar Bus	21h 55m	18:35	Madrid	Sur Bus Station	16:30	Brussels	Midi Bus Station	Economy	£42	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 14/12/2025 18:35:00 to Midi Bus Station, Brussels (Belgium) arriving at 15/12/2025 16:30:00. 50 Economy ticket for £42 per person are available. Travel duration is 21h 55m
FlixBus	21h 55m	14:50	Madrid	Sur Bus Station	12:45	Brussels	North Station	Economy	£51	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 14/12/2025 14:50:00 to North Station, Brussels (Belgium) arriving at 15/12/2025 12:45:00. 50 Economy ticket for £51 per person are available. Travel duration is 21h 55m
FlixBus	22h 55m	16:40	Madrid	Sur Bus Station	15:35	Brussels	North Station	Economy	£53	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 14/12/2025 16:40:00 to North Station, Brussels (Belgium) arriving at 15/12/2025 15:35:00. 50 Economy ticket for £53 per person are available. Travel duration is 22h 55m
FlixBus	26h 10m	20:50	Madrid	Sur Bus Station	23:00	Brussels	North Station	Economy	£53	A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 14/12/2025 20:50:00 to North Station, Brussels (Belgium) arriving at 15/12/2025 23:00:00. 50 Economy ticket for £53 per person are available. Travel duration is 26h 10m
BlaBlaCar Bus	22h 20m	22:30	Madrid	Sur Bus Station	20:50	Brussels	Midi Bus Station	Economy	£61	A Bus from BlaBlaCar Bus goes from Sur Bus Station, Madrid (Spain) at 14/12/2025 22:30:00 to Midi Bus Station, Brussels (Belgium) arriving at 15/12/2025 20:50:00. 50 Economy ticket for £61 per person are available. Travel duration is 22h 20m

Best Price Offer: The price for the cheapest coach from Madrid to Brussels is £42 on 14/12/2025. Flexible travellers save on ticket prices.

Frequency of bus connections between Madrid and Brussels

See here how frequent the connections between Madrid and Brussels are, during different times and days of the week.

Thursday is the busiest day, with more than 18 daily coaches from Madrid to Brussels. Friday has instead the fewest connections, with only 9 daily coaches between Madrid and Brussels.

The busiest time of the day is the Afternoon, with 44 coaches from Madrid to Brussels, while Evening sees the fewest connections between Madrid and Brussels, with 20 offers.

Facts about coaches from Madrid to Brussels

Compare all providers like FlixBus and BlaBlaCar Bus that travel 12 times every day by bus from Madrid to Brussels in one click! Book your bus ticket from Madrid to Brussels starting from £42!

Cheapest Bus	£42
Fastest Bus	21h 30m
Earliest Coach	14:50
Latest Coach	22:30
Daily Bus Connections	12 Ø
Distance	1,316.6 km
Coach Companies	FlixBus and BlaBlaCar Bus

Cheapest coach connections from Madrid to Brussels

Every day, 12 buses from 2 coach companies leave Madrid for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 09/12/2025 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 08/12

Tuesday 09/12

£44

Wednesday 10/12

Thursday 11/12

£49

Friday 12/12

£51

Saturday 13/12

£55

Sunday 14/12

£42

Monday 15/12

Tuesday 16/12

£54

Wednesday 17/12

£51

Thursday 18/12

Friday 19/12

£73

Saturday 20/12

Sunday 21/12

Monday 22/12

Tuesday 23/12

Wednesday 24/12

£85

Thursday 25/12

£88

Friday 26/12

Saturday 27/12

£97

Sunday 28/12

£105

Monday 29/12

Tuesday 30/12

£91

Wednesday 31/12

Thursday 01/01

£112

Friday 02/01

£83

Saturday 03/01

£114

Sunday 04/01

The cheapest time to travel from Madrid to Brussels

See here on which day and which time of the day you can find the cheapest bus ticket from Madrid to Brussels, for the next 30 days.

With a price starting from £42, Sunday is the cheapest day for a coach from Madrid to Brussels. Saturday instead is the most expensive day with prices starting from £55.

Evening is the cheapest day time for bus tickets from Madrid to Brussels, with £42. Afternoon is the most expensive time of the day with prices starting from £44.

How to save money travelling from Madrid to Brussels

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Madrid to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Madrid to Brussels, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Madrid to Brussels are also emptier.

All bus stations and stops in Madrid and Brussels

The map below shows you where to find all the bus stations in Madrid and Brussels.

Avenida de América Coach Station

Avenida de América 13

Coach Stop

Calle de Tiziano 40

Intercambiador de Moncloa

Calle de la Princesa 89n

Plaza de Castilla

Sur Bus Station

Calle de Méndez Álvaro 83

Midi Bus Station

Avenue Fonsny 1

North Station

Rue du Progrès 80

Congrès

Boulevard Pachéco 7

Central Station

City Tours

Rue du Marché Aux Herbes 82

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Madrid to Brussels? Compare all modes of transports from Madrid to Brussels.

Service and Comfort on the bus from Madrid to Brussels

Want to know which seat classes are available on the coaches from Madrid to Brussels? Or which bus companies serve the route Madrid to Brussels? Below you will find answers to your questions.

FAQs about the Madrid to Brussels bus

How much does a Madrid - Brussels coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Madrid - Brussels bus trip is available from £42 and takes 21h 55m. Compare offers and save money!

How much could I save by comparing buses from Madrid to Brussels?

The connection Madrid to Brussels is offered by 2 companies with ticket prices ranging from £42 to £104. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Madrid - Brussels route on average every day?

Each day, the bus route from Madrid to Brussels is offered by roughly 12 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Brussels from Madrid take?

The quickest coach from Madrid to Brussels is provided by FlixBus and takes 21h 30m. Coach tickets for this connection cost £51. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Madrid to Brussels?

The earliest bus to Brussels departs from Madrid at 14:50. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Madrid to Brussels?

The latest bus to Brussels departs from Madrid at 22:30. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Madrid - Brussels route?

Passengers looking to travel from Madrid to Brussels can travel with FlixBus and BlaBlaCar Bus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Madrid and Brussels?

You can check all the direct connections between Madrid and Brussels by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and BlaBlaCar Bus.

What can I take with me on the bus to Brussels from Madrid?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Madrid Brussels bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Madrid Brussels bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Madrid to Brussels on your planned travel date.

Available seat classes which are offered on the bus route Madrid to Brussels

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Madrid and to Brussels

Here’s an overview of the most popular bus routes to Madrid and to Brussels. Simply click on the connection of your choice, and you will find all the details about your bus route!