Compare all timetables for the bus from Madrid to Brussels
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 24h 20m | 15:55 | Madrid | Sur Bus Station | 16:15 | Brussels | North Station | Economy | £61 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 21/03/2026 15:55:00 to North Station, Brussels (Belgium) arriving at 22/03/2026 16:15:00. 50 Economy ticket for £61 per person are available. Travel duration is 24h 20m
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| FlixBus | 23h 55m | 15:55 | Madrid | Sur Bus Station | 15:50 | Brussels | Midi Bus Station | Economy | £61 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 21/03/2026 15:55:00 to Midi Bus Station, Brussels (Belgium) arriving at 22/03/2026 15:50:00. 50 Economy ticket for £61 per person are available. Travel duration is 23h 55m
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| FlixBus | 30h 15m | 15:55 | Madrid | Sur Bus Station | 22:10 | Brussels | Heysel | Economy | £63 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 21/03/2026 15:55:00 to Heysel, Brussels (Belgium) arriving at 22/03/2026 22:10:00. 50 Economy ticket for £63 per person are available. Travel duration is 30h 15m
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| FlixBus | 21h 55m | 14:50 | Madrid | Sur Bus Station | 12:45 | Brussels | Midi Bus Station | Economy | £65 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 21/03/2026 14:50:00 to Midi Bus Station, Brussels (Belgium) arriving at 22/03/2026 12:45:00. 50 Economy ticket for £65 per person are available. Travel duration is 21h 55m
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| FlixBus | 27h 40m | 23:25 | Madrid | Sur Bus Station | 03:05 | Brussels | Midi Bus Station | Economy | £65 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 21/03/2026 23:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 23/03/2026 03:05:00. 50 Economy ticket for £65 per person are available. Travel duration is 27h 40m
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ALSA22h 30m015:30MadridMendez Alvaro Train Station06:30Paris Orly AirportParis Orly Airport0EconomyA Bus from ALSA goes from Mendez Alvaro Train Station, Madrid (Spain) at 22/03/2026 15:30:00 to Paris Orly Airport, Paris Orly Airport (France) arriving at 23/03/2026 06:30:00. 50 Economy ticket for £32 per person are available. Travel duration is 15h 0m
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FlixBus5h 35m008:25Paris Orly AirportParis Orly Airport - Parking P4C14:00BrusselsNorth Station0EconomyA Bus from FlixBus goes from Paris Orly Airport - Parking P4C, Paris Orly Airport (France) at 23/03/2026 08:25:00 to North Station, Brussels (Belgium) arriving at 23/03/2026 14:00:00. 50 Economy ticket for £14 per person are available. Travel duration is 5h 35m
Waiting Time 1h 55m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 26h 35m | 22:35 | Madrid | Sur Bus Station | 01:10 | Brussels | Midi Bus Station | Economy | £66 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 25/03/2026 22:35:00 to Midi Bus Station, Brussels (Belgium) arriving at 27/03/2026 01:10:00. 50 Economy ticket for £66 per person are available. Travel duration is 26h 35m
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| FlixBus | 22h 35m | 22:35 | Madrid | Sur Bus Station | 21:10 | Brussels | North Station | Economy | £67 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 25/03/2026 22:35:00 to North Station, Brussels (Belgium) arriving at 26/03/2026 21:10:00. 50 Economy ticket for £67 per person are available. Travel duration is 22h 35m
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| FlixBus | 21h 55m | 14:50 | Madrid | Sur Bus Station | 12:45 | Brussels | Midi Bus Station | Economy | £74 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 25/03/2026 14:50:00 to Midi Bus Station, Brussels (Belgium) arriving at 26/03/2026 12:45:00. 50 Economy ticket for £74 per person are available. Travel duration is 21h 55m
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| FlixBus | 21h 30m | 20:25 | Madrid | Sur Bus Station | 17:55 | Brussels | Midi Bus Station | Economy | £79 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 25/03/2026 20:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 26/03/2026 17:55:00. 50 Economy ticket for £79 per person are available. Travel duration is 21h 30m
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| FlixBus | 22h 55m | 16:40 | Madrid | Sur Bus Station | 15:35 | Brussels | Midi Bus Station | Economy | £80 |
A Bus from FlixBus goes from Sur Bus Station, Madrid (Spain) at 25/03/2026 16:40:00 to Midi Bus Station, Brussels (Belgium) arriving at 26/03/2026 15:35:00. 50 Economy ticket for £80 per person are available. Travel duration is 22h 55m
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Gipsyy20h 30m015:30MadridSur Bus Station06:30Paris Orly AirportParis Orly Airport - Parking P4C0Premium EconomyA Bus from Gipsyy goes from Sur Bus Station, Madrid (Spain) at 25/03/2026 15:30:00 to Paris Orly Airport - Parking P4C, Paris Orly Airport (France) arriving at 26/03/2026 06:30:00. 50 Premium Economy ticket for £22 per person are available. Travel duration is 15h 0m
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Busbud5h 29m006:31Paris Orly AirportAéroport Orly 1-2-3 Coach Station12:00BrusselsMidi Bus Station0BasicA Bus from Busbud goes from Aéroport Orly 1-2-3 Coach Station, Paris Orly Airport (France) at 26/03/2026 06:31:00 to Midi Bus Station, Brussels (Belgium) arriving at 26/03/2026 12:00:00. 50 Basic ticket for £12 per person are available. Travel duration is 5h 29m
Waiting Time 0h 1m -
Best Price Offer: The price for the cheapest coach from Madrid to Brussels is £41 on 20/03/2026. Flexible travellers save on ticket prices.
Frequency of bus connections between Madrid and Brussels
Facts about coaches from Madrid to Brussels
Compare all providers like FlixBus that travel 11 times every day by bus from Madrid to Brussels in one click! Book your bus ticket from Madrid to Brussels starting from £41!
| Cheapest Bus | £41 |
| Fastest Bus | 21h 30m |
| Earliest Coach | 14:50 |
| Latest Coach | 22:35 |
| Daily Bus Connections | 11 Ø |
| Distance | 1,316.6 km |
| Coach Companies | FlixBus |
Cheapest coach connections from Madrid to Brussels
Every day, 11 buses from 1 coach companies leave Madrid for Brussels: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 21/03/2026 and for the following days.
The cheapest time to travel from Madrid to Brussels
How to save money travelling from Madrid to Brussels
Book the ticket from Madrid to Brussels in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Madrid to Brussels, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Madrid to Brussels are also emptier.All bus stations and stops in Madrid and Brussels
The map below shows you where to find all the bus stations in Madrid and Brussels.
Compare the bus with other modes of transport
Service and Comfort on the bus from Madrid to Brussels
FAQs about the Madrid to Brussels bus
How much does a Madrid - Brussels coach trip cost?
How much could I save by comparing buses from Madrid to Brussels?
How many connections are available for the Madrid - Brussels route on average every day?
How long does a bus to Brussels from Madrid take?
What time is the first bus from Madrid to Brussels?
What time is the last coach from Madrid to Brussels?
Which bus companies serve the Madrid - Brussels route?
Is there a direct bus between Madrid and Brussels?
What can I take with me on the bus to Brussels from Madrid?
What equipment is available for the Madrid Brussels bus route?
How does CheckMyBus find the best bus deals from Madrid to Brussels?
How does CheckMyBus technology work for trips from Madrid to Brussels?
Available seat classes which are offered on the bus route Madrid to Brussels
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Madrid and to Brussels
- Bus Routes to Madrid
- Almendralejo to Madrid coach
- Bus Andújar to Madrid
- Coaches Arévalo to Madrid
- Coach to Madrid from Ávila
- Coaches Benidorm to Madrid
- Bilbao to Madrid bus
- Buses Cáceres (ES) to Madrid
- Cordoba to Madrid coach
- Bus from Cuenca to Madrid
- Bus from Gijón to Madrid
- Coach from London to Madrid
- Malaga to Madrid bus
- Bus to Madrid from Marbella
- Coach to Madrid from Otero de Herreros
- Coach Ourense to Madrid
- Roquetas de Mar to Madrid bus
- Santander to Madrid bus
- Bus Soria to Madrid
- Bus Trujillo to Madrid
- Bus to Madrid from Zaragoza
- Bus Routes to Brussels
- Amsterdam to Brussels coach
- Coach Birmingham to Brussels
- Bus to Brussels from Bordeaux
- Buses Bristol to Brussels
- Bruges (BE) to Brussels bus
- Coach Cologne to Brussels
- The Hague to Brussels coach
- Buses Dover to Brussels
- Edinburgh to Brussels bus
- Buses Exeter to Brussels
- Bus Folkestone to Brussels
- Coach Ghent to Brussels
- Graz to Brussels coach
- Bus to Brussels from Kyiv
- Bus Manchester to Brussels
- Coach Montpellier to Brussels
- Bus to Brussels from Newcastle upon Tyne
- Porto to Brussels bus
- Buses Sunderland to Brussels
- Coaches Utrecht to Brussels
