What is the best way to travel from Mainz to Brussels?
Looking for a trip? Check and compare all the available Flights, Trains and Buses to Brussels from Mainz. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Brussels from Mainz?
You can reach Brussels with just £19 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus8h 25m009:50Frankfurt am Main AirportFrankfurt am Main Airport18:15BrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/02/2026 09:50:00 to North Station, Brussels (Belgium) arriving at 03/02/2026 18:15:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 25m
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FlixBus9h 20m015:05Frankfurt am Main AirportFrankfurt am Main Airport00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/02/2026 15:05:00 to North Station, Brussels (Belgium) arriving at 04/02/2026 00:25:00. 50 Economy ticket for £25 per person are available. Travel duration is 9h 20m
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FlixBus8h 25m019:10Frankfurt am Main AirportFrankfurt am Main Airport03:35BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/02/2026 19:10:00 to Midi Bus Station, Brussels (Belgium) arriving at 04/02/2026 03:35:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 25m
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EasyJet Airline23h 30m009:10Frankfurt am Main AirportFrankfurt am Main Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/02/2026 09:10:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/02/2026 08:40:00. 50 Economy ticket for £96 per person are available. Travel duration is 23h 30m
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Pegasus Group LTD18h 50m015:35Frankfurt am Main AirportFrankfurt am Main Airport10:25Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/02/2026 15:35:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 04/02/2026 10:25:00. 50 Economy ticket for £107 per person are available. Travel duration is 18h 50m
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Pegasus Group LTD22h 10m015:35Frankfurt am Main AirportFrankfurt am Main Airport13:45Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/02/2026 15:35:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 04/02/2026 13:45:00. 50 Economy ticket for £107 per person are available. Travel duration is 22h 10m
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AJet20h 30m013:55Frankfurt am Main AirportFrankfurt am Main Airport10:25Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from AJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/02/2026 13:55:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 04/02/2026 10:25:00. 50 Economy ticket for £108 per person are available. Travel duration is 20h 30m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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EasyJet Airline11h 25m009:10Frankfurt am Main AirportFrankfurt am Main Airport20:35Brussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/02/2026 09:10:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/02/2026 20:35:00. 50 Economy ticket for £85 per person are available. Travel duration is 11h 25m
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TAROM21h 35m011:15Frankfurt am Main AirportFrankfurt am Main Airport08:50Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from TAROM goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/02/2026 11:15:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 05/02/2026 08:50:00. 50 Economy ticket for £104 per person are available. Travel duration is 21h 35m
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Lufthansa12h 0m020:40Frankfurt am Main AirportFrankfurt am Main Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/02/2026 20:40:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 05/02/2026 08:40:00. 50 Economy ticket for £113 per person are available. Travel duration is 12h 0m
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Aer Lingus7h 30m010:45Frankfurt am Main AirportFrankfurt am Main Airport18:15Brussels AirportBrussels Airport0EconomyA Flight from Aer Lingus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/02/2026 10:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/02/2026 18:15:00. 50 Economy ticket for £119 per person are available. Travel duration is 7h 30m
Cheapest Flights Wednesday
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EasyJet Airline23h 20m009:20Frankfurt am Main AirportFrankfurt am Main Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/02/2026 09:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 06/02/2026 08:40:00. 50 Economy ticket for £99 per person are available. Travel duration is 23h 20m
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AJet20h 25m013:45Frankfurt am Main AirportFrankfurt am Main Airport10:10Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from AJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/02/2026 13:45:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 06/02/2026 10:10:00. 50 Economy ticket for £106 per person are available. Travel duration is 20h 25m
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Pegasus Group LTD18h 35m015:35Frankfurt am Main AirportFrankfurt am Main Airport10:10Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/02/2026 15:35:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 06/02/2026 10:10:00. 50 Economy ticket for £107 per person are available. Travel duration is 18h 35m
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AJet23h 0m013:45Frankfurt am Main AirportFrankfurt am Main Airport12:45Brussels AirportBrussels Airport0EconomyA Flight from AJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/02/2026 13:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 06/02/2026 12:45:00. 50 Economy ticket for £107 per person are available. Travel duration is 23h 0m
Cheapest Flights Thursday
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EasyJet Airline23h 25m020:10Frankfurt am Main AirportFrankfurt am Main Airport19:35Brussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/02/2026 20:10:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 07/02/2026 19:35:00. 50 Economy ticket for £99 per person are available. Travel duration is 23h 25m
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Aer Lingus13h 35m020:00Frankfurt am Main AirportFrankfurt am Main Airport09:35Brussels AirportBrussels Airport0EconomyA Flight from Aer Lingus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/02/2026 20:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 07/02/2026 09:35:00. 50 Economy ticket for £99 per person are available. Travel duration is 13h 35m
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Pegasus Group LTD15h 45m018:35Frankfurt am Main AirportFrankfurt am Main Airport10:20Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/02/2026 18:35:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 07/02/2026 10:20:00. 50 Economy ticket for £119 per person are available. Travel duration is 15h 45m
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Lufthansa22h 50m020:45Frankfurt am Main AirportFrankfurt am Main Airport19:35Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/02/2026 20:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 07/02/2026 19:35:00. 50 Economy ticket for £122 per person are available. Travel duration is 22h 50m
Cheapest Flights Friday
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FlixBus5h 45m012:20MainzCentral Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 07/02/2026 12:20:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 18:05:00. 50 Economy ticket for £19 per person are available. Travel duration is 5h 45m
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FlixBus7h 30m001:00MainzCentral Station08:30BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 07/02/2026 01:00:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 08:30:00. 50 Economy ticket for £24 per person are available. Travel duration is 7h 30m
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Deutsche Bahn2h 48m006:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station09:36BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 07/02/2026 06:48:00 to Central Station, Brussels (Belgium) arriving at 07/02/2026 09:36:00. 50 Economy ticket for £46 per person are available. Travel duration is 2h 48m
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Deutsche Bahn5h 48m017:59Frankfurt am Main AirportFrankfurt am Main Airport Train Station23:47BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 07/02/2026 17:59:00 to Central Station, Brussels (Belgium) arriving at 07/02/2026 23:47:00. 50 Economy ticket for £46 per person are available. Travel duration is 5h 48m
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Deutsche Bahn3h 31m020:16Frankfurt am Main AirportFrankfurt am Main Airport Train Station23:47BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 07/02/2026 20:16:00 to Central Station, Brussels (Belgium) arriving at 07/02/2026 23:47:00. 50 Economy ticket for £46 per person are available. Travel duration is 3h 31m
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Deutsche Bahn3h 25m020:22Frankfurt am Main AirportFrankfurt am Main Airport Train Station23:47BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 07/02/2026 20:22:00 to Central Station, Brussels (Belgium) arriving at 07/02/2026 23:47:00. 50 Economy ticket for £52 per person are available. Travel duration is 3h 25m
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EasyJet Airline23h 25m009:15Frankfurt am Main AirportFrankfurt am Main Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/02/2026 09:15:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/02/2026 08:40:00. 50 Economy ticket for £106 per person are available. Travel duration is 23h 25m
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Pegasus Group LTD15h 50m018:35Frankfurt am Main AirportFrankfurt am Main Airport10:25Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/02/2026 18:35:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 08/02/2026 10:25:00. 50 Economy ticket for £161 per person are available. Travel duration is 15h 50m
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Lufthansa18h 15m015:20Frankfurt am Main AirportFrankfurt am Main Airport09:35Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/02/2026 15:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/02/2026 09:35:00. 50 Economy ticket for £171 per person are available. Travel duration is 18h 15m
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Condor12h 30m020:10Frankfurt am Main AirportFrankfurt am Main Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/02/2026 20:10:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/02/2026 08:40:00. 50 Economy ticket for £177 per person are available. Travel duration is 12h 30m
Cheapest Buses Saturday
Cheapest Trains Saturday
Cheapest Flights Saturday
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FlixBus6h 55m000:25Frankfurt am Main AirportFrankfurt am Main Airport07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 00:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 08/02/2026 07:20:00. 50 Economy ticket for £24 per person are available. Travel duration is 6h 55m
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FlixBus7h 20m006:35Frankfurt am Main AirportFrankfurt am Main Airport13:55BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 06:35:00 to Midi Bus Station, Brussels (Belgium) arriving at 08/02/2026 13:55:00. 50 Economy ticket for £24 per person are available. Travel duration is 7h 20m
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FlixBus6h 50m002:30Frankfurt am Main AirportFrankfurt am Main Airport09:20BrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 02:30:00 to North Station, Brussels (Belgium) arriving at 08/02/2026 09:20:00. 50 Economy ticket for £25 per person are available. Travel duration is 6h 50m
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FlixBus8h 5m006:35Frankfurt am Main AirportFrankfurt am Main Airport14:40BrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 06:35:00 to North Station, Brussels (Belgium) arriving at 08/02/2026 14:40:00. 50 Economy ticket for £31 per person are available. Travel duration is 8h 5m
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Pegasus Group LTD22h 25m015:30Frankfurt am Main AirportFrankfurt am Main Airport13:55Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 15:30:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 09/02/2026 13:55:00. 50 Economy ticket for £122 per person are available. Travel duration is 22h 25m
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EasyJet Airline23h 30m009:10Frankfurt am Main AirportFrankfurt am Main Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 09:10:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 09/02/2026 08:40:00. 50 Economy ticket for £122 per person are available. Travel duration is 23h 30m
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Pegasus Group LTD22h 45m011:40Frankfurt am Main AirportFrankfurt am Main Airport10:25Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 11:40:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 09/02/2026 10:25:00. 50 Economy ticket for £135 per person are available. Travel duration is 22h 45m
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AJet20h 45m013:40Frankfurt am Main AirportFrankfurt am Main Airport10:25Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from AJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 13:40:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 09/02/2026 10:25:00. 50 Economy ticket for £141 per person are available. Travel duration is 20h 45m
Cheapest Buses Sunday
Cheapest Flights Sunday
What are the fastest trips from Mainz to Brussels?
You can get to Brussels from Mainz in just 1h 0m with a Flight from Lufthansa. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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FlixBus8h 25m009:50Frankfurt am Main AirportFrankfurt am Main Airport18:15BrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/02/2026 09:50:00 to North Station, Brussels (Belgium) arriving at 03/02/2026 18:15:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 25m
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FlixBus8h 25m019:10Frankfurt am Main AirportFrankfurt am Main Airport03:35BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/02/2026 19:10:00 to Midi Bus Station, Brussels (Belgium) arriving at 04/02/2026 03:35:00. 50 Economy ticket for £25 per person are available. Travel duration is 8h 25m
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FlixBus9h 20m015:05Frankfurt am Main AirportFrankfurt am Main Airport00:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/02/2026 15:05:00 to North Station, Brussels (Belgium) arriving at 04/02/2026 00:25:00. 50 Economy ticket for £25 per person are available. Travel duration is 9h 20m
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Iberia14h 15m019:35Frankfurt am Main AirportFrankfurt am Main Airport09:50Brussels AirportBrussels Airport0EconomyA Flight from Iberia goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/02/2026 19:35:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/02/2026 09:50:00. 50 Economy ticket for £154 per person are available. Travel duration is 14h 15m
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Air Europa14h 45m019:05Frankfurt am Main AirportFrankfurt am Main Airport09:50Brussels AirportBrussels Airport0EconomyA Flight from Air Europa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/02/2026 19:05:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/02/2026 09:50:00. 50 Economy ticket for £165 per person are available. Travel duration is 14h 45m
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Lufthansa15h 45m016:55Frankfurt am Main AirportFrankfurt am Main Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/02/2026 16:55:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/02/2026 08:40:00. 50 Economy ticket for £160 per person are available. Travel duration is 15h 45m
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Lufthansa17h 45m020:35Frankfurt am Main AirportFrankfurt am Main Airport14:20Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 03/02/2026 20:35:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 04/02/2026 14:20:00. 50 Economy ticket for £298 per person are available. Travel duration is 17h 45m
Fastest Buses Tuesday
Fastest Flights Tuesday
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Brussels Airlines1h 10m009:00Frankfurt am Main AirportFrankfurt am Main Airport10:10Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/02/2026 09:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/02/2026 10:10:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 10m
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TAROM7h 5m011:15Frankfurt am Main AirportFrankfurt am Main Airport18:20Brussels AirportBrussels Airport0EconomyA Flight from TAROM goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/02/2026 11:15:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/02/2026 18:20:00. 50 Economy ticket for £138 per person are available. Travel duration is 7h 5m
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Aer Lingus7h 30m010:45Frankfurt am Main AirportFrankfurt am Main Airport18:15Brussels AirportBrussels Airport0EconomyA Flight from Aer Lingus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/02/2026 10:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/02/2026 18:15:00. 50 Economy ticket for £119 per person are available. Travel duration is 7h 30m
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Lufthansa11h 20m021:00Frankfurt am Main AirportFrankfurt am Main Airport08:20Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/02/2026 21:00:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 05/02/2026 08:20:00. 50 Economy ticket for £146 per person are available. Travel duration is 11h 20m
Fastest Flights Wednesday
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Austrian Airlines4h 55m006:50Frankfurt am Main AirportFrankfurt am Main Airport11:45Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Austrian Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/02/2026 06:50:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 05/02/2026 11:45:00. 50 Economy ticket for £155 per person are available. Travel duration is 4h 55m
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TAROM6h 15m011:15Frankfurt am Main AirportFrankfurt am Main Airport17:30Brussels AirportBrussels Airport0EconomyA Flight from TAROM goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/02/2026 11:15:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 05/02/2026 17:30:00. 50 Economy ticket for £152 per person are available. Travel duration is 6h 15m
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Croatia Airlines7h 5m009:30Frankfurt am Main AirportFrankfurt am Main Airport16:35Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Croatia Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/02/2026 09:30:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 05/02/2026 16:35:00. 50 Economy ticket for £117 per person are available. Travel duration is 7h 5m
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Lufthansa7h 35m012:50Frankfurt am Main AirportFrankfurt am Main Airport20:25Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 05/02/2026 12:50:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 05/02/2026 20:25:00. 50 Economy ticket for £112 per person are available. Travel duration is 7h 35m
Fastest Flights Thursday
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Brussels Airlines1h 10m009:00Frankfurt am Main AirportFrankfurt am Main Airport10:10Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/02/2026 09:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 06/02/2026 10:10:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 10m
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Swiss International Air Lines3h 45m009:50Frankfurt am Main AirportFrankfurt am Main Airport13:35Brussels AirportBrussels Airport0EconomyA Flight from Swiss International Air Lines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/02/2026 09:50:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 06/02/2026 13:35:00. 50 Economy ticket for £172 per person are available. Travel duration is 3h 45m
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Lufthansa7h 25m013:00Frankfurt am Main AirportFrankfurt am Main Airport20:25Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/02/2026 13:00:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 06/02/2026 20:25:00. 50 Economy ticket for £160 per person are available. Travel duration is 7h 25m
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Lufthansa7h 45m014:35Frankfurt am Main AirportFrankfurt am Main Airport22:20Antwerp AirportAntwerp Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/02/2026 14:35:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 06/02/2026 22:20:00. 50 Economy ticket for £322 per person are available. Travel duration is 7h 45m
Fastest Flights Friday
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Deutsche Bahn2h 48m006:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station09:36BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 07/02/2026 06:48:00 to Central Station, Brussels (Belgium) arriving at 07/02/2026 09:36:00. 50 Economy ticket for £46 per person are available. Travel duration is 2h 48m
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Deutsche Bahn3h 25m020:22Frankfurt am Main AirportFrankfurt am Main Airport Train Station23:47BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 07/02/2026 20:22:00 to Central Station, Brussels (Belgium) arriving at 07/02/2026 23:47:00. 50 Economy ticket for £52 per person are available. Travel duration is 3h 25m
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Deutsche Bahn3h 31m020:16Frankfurt am Main AirportFrankfurt am Main Airport Train Station23:47BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 07/02/2026 20:16:00 to Central Station, Brussels (Belgium) arriving at 07/02/2026 23:47:00. 50 Economy ticket for £46 per person are available. Travel duration is 3h 31m
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Deutsche Bahn5h 37m007:59Frankfurt am Main AirportFrankfurt am Main Airport Train Station13:36BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 07/02/2026 07:59:00 to Central Station, Brussels (Belgium) arriving at 07/02/2026 13:36:00. 50 Economy ticket for £53 per person are available. Travel duration is 5h 37m
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FlixBus5h 45m012:20MainzCentral Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 07/02/2026 12:20:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 18:05:00. 50 Economy ticket for £19 per person are available. Travel duration is 5h 45m
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FlixBus7h 30m001:00MainzCentral Station08:30BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 07/02/2026 01:00:00 to North Station, Brussels (Belgium) arriving at 07/02/2026 08:30:00. 50 Economy ticket for £24 per person are available. Travel duration is 7h 30m
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Lufthansa8h 10m007:45Frankfurt am Main AirportFrankfurt am Main Airport15:55Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/02/2026 07:45:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 07/02/2026 15:55:00. 50 Economy ticket for £234 per person are available. Travel duration is 8h 10m
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Lufthansa11h 20m021:00Frankfurt am Main AirportFrankfurt am Main Airport08:20Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/02/2026 21:00:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 08/02/2026 08:20:00. 50 Economy ticket for £216 per person are available. Travel duration is 11h 20m
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Condor12h 30m020:10Frankfurt am Main AirportFrankfurt am Main Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/02/2026 20:10:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/02/2026 08:40:00. 50 Economy ticket for £177 per person are available. Travel duration is 12h 30m
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Pegasus Group LTD15h 50m018:35Frankfurt am Main AirportFrankfurt am Main Airport10:25Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 07/02/2026 18:35:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 08/02/2026 10:25:00. 50 Economy ticket for £161 per person are available. Travel duration is 15h 50m
Fastest Trains Saturday
Fastest Buses Saturday
Fastest Flights Saturday
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Lufthansa1h 0m007:20Frankfurt am Main AirportFrankfurt am Main Airport08:20Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 07:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/02/2026 08:20:00. 50 Economy ticket for £187 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 10m009:00Frankfurt am Main AirportFrankfurt am Main Airport10:10Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 09:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/02/2026 10:10:00. 50 Economy ticket for £187 per person are available. Travel duration is 1h 10m
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Lufthansa7h 20m013:20Frankfurt am Main AirportFrankfurt am Main Airport20:40Antwerp AirportAntwerp Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 13:20:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 08/02/2026 20:40:00. 50 Economy ticket for £574 per person are available. Travel duration is 7h 20m
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Lufthansa8h 55m010:25Frankfurt am Main AirportFrankfurt am Main Airport19:20Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 10:25:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 08/02/2026 19:20:00. 50 Economy ticket for £256 per person are available. Travel duration is 8h 55m
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FlixBus6h 50m002:30Frankfurt am Main AirportFrankfurt am Main Airport09:20BrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 02:30:00 to North Station, Brussels (Belgium) arriving at 08/02/2026 09:20:00. 50 Economy ticket for £25 per person are available. Travel duration is 6h 50m
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FlixBus6h 55m000:25Frankfurt am Main AirportFrankfurt am Main Airport07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 00:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 08/02/2026 07:20:00. 50 Economy ticket for £24 per person are available. Travel duration is 6h 55m
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FlixBus7h 20m006:35Frankfurt am Main AirportFrankfurt am Main Airport13:55BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 06:35:00 to Midi Bus Station, Brussels (Belgium) arriving at 08/02/2026 13:55:00. 50 Economy ticket for £24 per person are available. Travel duration is 7h 20m
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FlixBus8h 5m006:35Frankfurt am Main AirportFrankfurt am Main Airport14:40BrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/02/2026 06:35:00 to North Station, Brussels (Belgium) arriving at 08/02/2026 14:40:00. 50 Economy ticket for £31 per person are available. Travel duration is 8h 5m
Fastest Flights Sunday
Fastest Buses Sunday
Here you will find all operators and timetables for a
Bus from Mainz to Brussels
What are the most popular stations in Mainz and Brussels?
In Mainz, you will usually depart from Central Station, Central Bus Station or Laubenheim Train Station, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brussels from Mainz? With 14 connections between 1 Flight, Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Mainz and Brussels, you can pay as low as £19 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Lufthansa: you will get to Brussels in just 1h 0m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Mainz and Brussels are Lufthansa, Pegasus Group LTD and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Mainz and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Budenheim or to Saint-Gilles, and look at flights from Frankfurt am Main Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Mainz to Brussels?
The most popular companies between Mainz and Brussels, are Lufthansa, Pegasus Group LTD and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Train companies: Deutsche Bahn
Airlines: Lufthansa, Pegasus Group LTD, EasyJet Airline and 13 more.
All you need to know when you travel from Mainz to Brussels
Check all information on comfort and services on all modes of transports from Mainz to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Mainz to Brussels
How can I reach Brussels from Mainz?
Every day, there are on average 14 connections between Flight, Train and Bus, with which you can get to Brussels from Mainz.
How far is Brussels from Mainz?
The distance between Mainz and Brussels is 291.9 km.
What is the most ecofriendly mode of transport between Mainz and Brussels?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 8 kgs of CO2, a train 10 kgs, a car 50 kgs, and a flight 72 kgs.
What is the cheapest mode of transport from Mainz to Brussels?
You can get to Brussels with just £19 by taking a Bus from FlixBus.
What is the fastest way to get from Mainz to Brussels?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 1h 0m with a Flight from Lufthansa.
More routes to Mainz and to Brussels
Looking for more options? Here you can see the most popular routes to Mainz and to Brussels. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Mainz
- Berlin to Mainz
- Brussels to Mainz
- Dresden to Mainz
- Frankfurt am Main Airport to Mainz
- Frankfurt Hahn Airport to Mainz
- Freiburg to Mainz
- Heidelberg to Mainz
- Kaiserslautern to Mainz
- Katowice to Mainz
- Koblenz to Mainz
- Munich to Mainz
- Saarbruecken to Mainz
- Simmern (Hunsrück) to Mainz
- Trips to Brussels
- Aachen to Brussels
- Amsterdam to Brussels
- Antwerp to Brussels
- Barcelona to Brussels
- Basel to Brussels
- Birmingham to Brussels
- Bordeaux to Brussels
- Bristol to Brussels
- Brussels South Charleroi Airport to Brussels
- Cologne/Bonn Airport to Brussels
- Dusseldorf to Brussels
- Edinburgh to Brussels
- Le Mans to Brussels
- Lille to Brussels
- Lisbon to Brussels
- London to Brussels
- Lyon to Brussels
- Newcastle upon Tyne to Brussels
- Nottingham to Brussels
- Paris to Brussels
- Prague to Brussels
- The Hague to Brussels
- Toulouse to Brussels
- Zurich to Brussels
