What is the best way to travel from Mainz to Brussels?
Looking for a trip? Check and compare all the available Flights, Trains and Buses to Brussels from Mainz. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Brussels from Mainz?
You can reach Brussels with just £17 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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EasyJet Airline13h 15m019:25Frankfurt am Main AirportFrankfurt am Main Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 21/03/2026 19:25:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 22/03/2026 08:40:00. 50 Economy ticket for £92 per person are available. Travel duration is 13h 15m
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Lufthansa11h 55m020:45Frankfurt am Main AirportFrankfurt am Main Airport08:40Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 21/03/2026 20:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 22/03/2026 08:40:00. 50 Economy ticket for £116 per person are available. Travel duration is 11h 55m
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Lufthansa25h 30m006:50Frankfurt am Main AirportFrankfurt am Main Airport08:20Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 21/03/2026 06:50:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 22/03/2026 08:20:00. 50 Economy ticket for £145 per person are available. Travel duration is 25h 30m
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Brussels Airlines1h 10m009:00Frankfurt am Main AirportFrankfurt am Main Airport10:10Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 21/03/2026 09:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 21/03/2026 10:10:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 10m
Cheapest Flights Saturday
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Deutsche Bahn9h 24m019:20MainzCentral Station04:44BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Mainz (Germany) at 22/03/2026 19:20:00 to Central Station, Brussels (Belgium) arriving at 23/03/2026 04:44:00. 50 Economy ticket for £43 per person are available. Travel duration is 9h 24m
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BlaBlaCar Bus13h 48m012:25Frankfurt am Main AirportFrankfurt am Main Airport02:13BrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 22/03/2026 12:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 23/03/2026 02:13:00. 50 Economy ticket for £56 per person are available. Travel duration is 13h 48m
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Lufthansa1h 0m007:20Frankfurt am Main AirportFrankfurt am Main Airport08:20Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 22/03/2026 07:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 22/03/2026 08:20:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 10m009:00Frankfurt am Main AirportFrankfurt am Main Airport10:10Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 22/03/2026 09:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 22/03/2026 10:10:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 10m
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Brussels Airlines1h 5m011:30Frankfurt am Main AirportFrankfurt am Main Airport12:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 22/03/2026 11:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 22/03/2026 12:35:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m016:25Frankfurt am Main AirportFrankfurt am Main Airport17:30Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 22/03/2026 16:25:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 22/03/2026 17:30:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 5m
Cheapest Trains Sunday
Cheapest Buses Sunday
Cheapest Flights Sunday
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Deutsche Bahn3h 46m020:29Frankfurt am Main AirportFrankfurt am Main Airport Train Station00:15BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 23/03/2026 20:29:00 to Central Station, Brussels (Belgium) arriving at 24/03/2026 00:15:00. 50 Economy ticket for £29 per person are available. Travel duration is 3h 46m
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Deutsche Bahn3h 27m018:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station22:15BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 23/03/2026 18:48:00 to Central Station, Brussels (Belgium) arriving at 23/03/2026 22:15:00. 50 Economy ticket for £36 per person are available. Travel duration is 3h 27m
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Deutsche Bahn2h 56m018:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station21:44BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 23/03/2026 18:48:00 to Central Station, Brussels (Belgium) arriving at 23/03/2026 21:44:00. 50 Economy ticket for £36 per person are available. Travel duration is 2h 56m
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Deutsche Bahn2h 56m006:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station09:44BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 23/03/2026 06:48:00 to Central Station, Brussels (Belgium) arriving at 23/03/2026 09:44:00. 50 Economy ticket for £46 per person are available. Travel duration is 2h 56m
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Lufthansa1h 0m007:20Frankfurt am Main AirportFrankfurt am Main Airport08:20Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 23/03/2026 07:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 23/03/2026 08:20:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:30Frankfurt am Main AirportFrankfurt am Main Airport12:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 23/03/2026 11:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 23/03/2026 12:35:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30Frankfurt am Main AirportFrankfurt am Main Airport13:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 23/03/2026 12:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 23/03/2026 13:35:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 0m021:30Frankfurt am Main AirportFrankfurt am Main Airport22:30Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 23/03/2026 21:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 23/03/2026 22:30:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 0m
Cheapest Trains Monday
Cheapest Flights Monday
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FlixBus6h 55m000:25Frankfurt am Main AirportFrankfurt am Main Airport07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 25/03/2026 00:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 25/03/2026 07:20:00. 50 Economy ticket for £17 per person are available. Travel duration is 6h 55m
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FlixBus7h 30m001:00MainzCentral Station08:30BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 25/03/2026 01:00:00 to North Station, Brussels (Belgium) arriving at 25/03/2026 08:30:00. 50 Economy ticket for £21 per person are available. Travel duration is 7h 30m
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FlixBus8h 55m010:30MainzCentral Station19:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 25/03/2026 10:30:00 to North Station, Brussels (Belgium) arriving at 25/03/2026 19:25:00. 50 Economy ticket for £21 per person are available. Travel duration is 8h 55m
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FlixBus9h 50m022:40MainzCentral Station08:30BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 25/03/2026 22:40:00 to North Station, Brussels (Belgium) arriving at 26/03/2026 08:30:00. 50 Economy ticket for £21 per person are available. Travel duration is 9h 50m
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Brussels Airlines1h 10m009:00Frankfurt am Main AirportFrankfurt am Main Airport10:10Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 25/03/2026 09:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 25/03/2026 10:10:00. 50 Economy ticket for £219 per person are available. Travel duration is 1h 10m
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Brussels Airlines1h 5m011:30Frankfurt am Main AirportFrankfurt am Main Airport12:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 25/03/2026 11:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 25/03/2026 12:35:00. 50 Economy ticket for £219 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30Frankfurt am Main AirportFrankfurt am Main Airport13:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 25/03/2026 12:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 25/03/2026 13:35:00. 50 Economy ticket for £219 per person are available. Travel duration is 1h 5m
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Lufthansa1h 0m007:20Frankfurt am Main AirportFrankfurt am Main Airport08:20Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 25/03/2026 07:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 25/03/2026 08:20:00. 50 Economy ticket for £252 per person are available. Travel duration is 1h 0m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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Lufthansa1h 0m007:20Frankfurt am Main AirportFrankfurt am Main Airport08:20Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 26/03/2026 07:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 26/03/2026 08:20:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:30Frankfurt am Main AirportFrankfurt am Main Airport12:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 26/03/2026 11:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 26/03/2026 12:35:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30Frankfurt am Main AirportFrankfurt am Main Airport13:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 26/03/2026 12:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 26/03/2026 13:35:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m016:25Frankfurt am Main AirportFrankfurt am Main Airport17:30Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 26/03/2026 16:25:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 26/03/2026 17:30:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 5m
Cheapest Flights Thursday
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FlixBus5h 45m012:20MainzCentral Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 27/03/2026 12:20:00 to North Station, Brussels (Belgium) arriving at 27/03/2026 18:05:00. 50 Economy ticket for £19 per person are available. Travel duration is 5h 45m
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FlixBus6h 55m000:25Frankfurt am Main AirportFrankfurt am Main Airport07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 27/03/2026 00:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 27/03/2026 07:20:00. 50 Economy ticket for £20 per person are available. Travel duration is 6h 55m
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FlixBus7h 20m006:35Frankfurt am Main AirportFrankfurt am Main Airport13:55BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 27/03/2026 06:35:00 to Midi Bus Station, Brussels (Belgium) arriving at 27/03/2026 13:55:00. 50 Economy ticket for £20 per person are available. Travel duration is 7h 20m
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BlaBlaCar Bus13h 48m012:25Frankfurt am Main AirportFrankfurt am Main Airport02:13BrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 27/03/2026 12:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 28/03/2026 02:13:00. 50 Economy ticket for £43 per person are available. Travel duration is 13h 48m
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Eurowings25h 5m018:35Frankfurt am Main AirportFrankfurt am Main Airport19:40Brussels AirportBrussels Airport0EconomyA Flight from Eurowings goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 27/03/2026 18:35:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 28/03/2026 19:40:00. 50 Economy ticket for £134 per person are available. Travel duration is 25h 5m
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Eurowings1h 5m012:30Frankfurt am Main AirportFrankfurt am Main Airport13:35Brussels AirportBrussels Airport0EconomyA Flight from Eurowings goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 27/03/2026 12:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 27/03/2026 13:35:00. 50 Economy ticket for £169 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 10m009:00Frankfurt am Main AirportFrankfurt am Main Airport10:10Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 27/03/2026 09:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 27/03/2026 10:10:00. 50 Economy ticket for £169 per person are available. Travel duration is 1h 10m
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Brussels Airlines1h 5m011:30Frankfurt am Main AirportFrankfurt am Main Airport12:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 27/03/2026 11:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 27/03/2026 12:35:00. 50 Economy ticket for £169 per person are available. Travel duration is 1h 5m
Cheapest Buses Friday
Cheapest Flights Friday
What are the fastest trips from Mainz to Brussels?
You can get to Brussels from Mainz in just 1h 0m with a Flight from Lufthansa. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Brussels Airlines1h 10m009:00Frankfurt am Main AirportFrankfurt am Main Airport10:10Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 21/03/2026 09:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 21/03/2026 10:10:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 10m
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Lufthansa5h 55m010:00Frankfurt am Main AirportFrankfurt am Main Airport15:55Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 21/03/2026 10:00:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 21/03/2026 15:55:00. 50 Economy ticket for £209 per person are available. Travel duration is 5h 55m
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Lufthansa8h 10m007:45Frankfurt am Main AirportFrankfurt am Main Airport15:55Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 21/03/2026 07:45:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 21/03/2026 15:55:00. 50 Economy ticket for £162 per person are available. Travel duration is 8h 10m
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Lufthansa11h 20m021:00Frankfurt am Main AirportFrankfurt am Main Airport08:20Brussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 21/03/2026 21:00:00 to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 22/03/2026 08:20:00. 50 Economy ticket for £170 per person are available. Travel duration is 11h 20m
Fastest Flights Saturday
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Lufthansa1h 0m007:20Frankfurt am Main AirportFrankfurt am Main Airport08:20Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 22/03/2026 07:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 22/03/2026 08:20:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m021:30Frankfurt am Main AirportFrankfurt am Main Airport22:30Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 22/03/2026 21:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 22/03/2026 22:30:00. 50 Economy ticket for £182 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:30Frankfurt am Main AirportFrankfurt am Main Airport12:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 22/03/2026 11:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 22/03/2026 12:35:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m016:25Frankfurt am Main AirportFrankfurt am Main Airport17:30Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 22/03/2026 16:25:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 22/03/2026 17:30:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 5m
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Deutsche Bahn9h 24m019:20MainzCentral Station04:44BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Mainz (Germany) at 22/03/2026 19:20:00 to Central Station, Brussels (Belgium) arriving at 23/03/2026 04:44:00. 50 Economy ticket for £43 per person are available. Travel duration is 9h 24m
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BlaBlaCar Bus13h 48m012:25Frankfurt am Main AirportFrankfurt am Main Airport02:13BrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 22/03/2026 12:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 23/03/2026 02:13:00. 50 Economy ticket for £56 per person are available. Travel duration is 13h 48m
Fastest Flights Sunday
Fastest Trains Sunday
Fastest Buses Sunday
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Lufthansa1h 0m007:20Frankfurt am Main AirportFrankfurt am Main Airport08:20Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 23/03/2026 07:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 23/03/2026 08:20:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 0m021:30Frankfurt am Main AirportFrankfurt am Main Airport22:30Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 23/03/2026 21:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 23/03/2026 22:30:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:30Frankfurt am Main AirportFrankfurt am Main Airport12:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 23/03/2026 11:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 23/03/2026 12:35:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30Frankfurt am Main AirportFrankfurt am Main Airport13:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 23/03/2026 12:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 23/03/2026 13:35:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 5m
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Deutsche Bahn2h 56m018:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station21:44BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 23/03/2026 18:48:00 to Central Station, Brussels (Belgium) arriving at 23/03/2026 21:44:00. 50 Economy ticket for £36 per person are available. Travel duration is 2h 56m
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Deutsche Bahn2h 56m006:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station09:44BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 23/03/2026 06:48:00 to Central Station, Brussels (Belgium) arriving at 23/03/2026 09:44:00. 50 Economy ticket for £46 per person are available. Travel duration is 2h 56m
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Deutsche Bahn3h 27m018:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station22:15BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 23/03/2026 18:48:00 to Central Station, Brussels (Belgium) arriving at 23/03/2026 22:15:00. 50 Economy ticket for £36 per person are available. Travel duration is 3h 27m
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Deutsche Bahn3h 46m020:29Frankfurt am Main AirportFrankfurt am Main Airport Train Station00:15BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 23/03/2026 20:29:00 to Central Station, Brussels (Belgium) arriving at 24/03/2026 00:15:00. 50 Economy ticket for £29 per person are available. Travel duration is 3h 46m
Fastest Flights Monday
Fastest Trains Monday
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Lufthansa1h 0m007:20Frankfurt am Main AirportFrankfurt am Main Airport08:20Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 25/03/2026 07:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 25/03/2026 08:20:00. 50 Economy ticket for £252 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:30Frankfurt am Main AirportFrankfurt am Main Airport12:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 25/03/2026 11:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 25/03/2026 12:35:00. 50 Economy ticket for £219 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30Frankfurt am Main AirportFrankfurt am Main Airport13:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 25/03/2026 12:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 25/03/2026 13:35:00. 50 Economy ticket for £219 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 10m009:00Frankfurt am Main AirportFrankfurt am Main Airport10:10Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 25/03/2026 09:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 25/03/2026 10:10:00. 50 Economy ticket for £219 per person are available. Travel duration is 1h 10m
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FlixBus6h 55m000:25Frankfurt am Main AirportFrankfurt am Main Airport07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 25/03/2026 00:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 25/03/2026 07:20:00. 50 Economy ticket for £17 per person are available. Travel duration is 6h 55m
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FlixBus7h 30m001:00MainzCentral Station08:30BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 25/03/2026 01:00:00 to North Station, Brussels (Belgium) arriving at 25/03/2026 08:30:00. 50 Economy ticket for £21 per person are available. Travel duration is 7h 30m
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FlixBus8h 55m010:30MainzCentral Station19:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 25/03/2026 10:30:00 to North Station, Brussels (Belgium) arriving at 25/03/2026 19:25:00. 50 Economy ticket for £21 per person are available. Travel duration is 8h 55m
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FlixBus9h 35m009:50Frankfurt am Main AirportFrankfurt am Main Airport19:25BrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 25/03/2026 09:50:00 to North Station, Brussels (Belgium) arriving at 25/03/2026 19:25:00. 50 Economy ticket for £25 per person are available. Travel duration is 9h 35m
Fastest Flights Wednesday
Fastest Buses Wednesday
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Lufthansa1h 0m007:20Frankfurt am Main AirportFrankfurt am Main Airport08:20Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 26/03/2026 07:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 26/03/2026 08:20:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:30Frankfurt am Main AirportFrankfurt am Main Airport12:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 26/03/2026 11:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 26/03/2026 12:35:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30Frankfurt am Main AirportFrankfurt am Main Airport13:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 26/03/2026 12:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 26/03/2026 13:35:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m016:25Frankfurt am Main AirportFrankfurt am Main Airport17:30Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 26/03/2026 16:25:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 26/03/2026 17:30:00. 50 Economy ticket for £145 per person are available. Travel duration is 1h 5m
Fastest Flights Thursday
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Lufthansa1h 0m007:20Frankfurt am Main AirportFrankfurt am Main Airport08:20Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 27/03/2026 07:20:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 27/03/2026 08:20:00. 50 Economy ticket for £297 per person are available. Travel duration is 1h 0m
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Eurowings1h 5m012:30Frankfurt am Main AirportFrankfurt am Main Airport13:35Brussels AirportBrussels Airport0EconomyA Flight from Eurowings goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 27/03/2026 12:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 27/03/2026 13:35:00. 50 Economy ticket for £169 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m011:30Frankfurt am Main AirportFrankfurt am Main Airport12:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 27/03/2026 11:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 27/03/2026 12:35:00. 50 Economy ticket for £169 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 10m009:00Frankfurt am Main AirportFrankfurt am Main Airport10:10Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 27/03/2026 09:00:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 27/03/2026 10:10:00. 50 Economy ticket for £169 per person are available. Travel duration is 1h 10m
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FlixBus5h 45m012:20MainzCentral Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 27/03/2026 12:20:00 to North Station, Brussels (Belgium) arriving at 27/03/2026 18:05:00. 50 Economy ticket for £19 per person are available. Travel duration is 5h 45m
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FlixBus6h 55m000:25Frankfurt am Main AirportFrankfurt am Main Airport07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 27/03/2026 00:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 27/03/2026 07:20:00. 50 Economy ticket for £20 per person are available. Travel duration is 6h 55m
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FlixBus7h 20m006:35Frankfurt am Main AirportFrankfurt am Main Airport13:55BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 27/03/2026 06:35:00 to Midi Bus Station, Brussels (Belgium) arriving at 27/03/2026 13:55:00. 50 Economy ticket for £20 per person are available. Travel duration is 7h 20m
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BlaBlaCar Bus13h 48m012:25Frankfurt am Main AirportFrankfurt am Main Airport02:13BrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 27/03/2026 12:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 28/03/2026 02:13:00. 50 Economy ticket for £43 per person are available. Travel duration is 13h 48m
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Here you will find all operators and timetables for a
Bus from Mainz to Brussels
What are the most popular stations in Mainz and Brussels?
In Mainz, you will usually depart from Central Station, Central Bus Station or Laubenheim Train Station, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brussels from Mainz? With 8 connections between 2 Flight, Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Mainz and Brussels, you can pay as low as £17 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Lufthansa: you will get to Brussels in just 1h 0m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Mainz and Brussels are Lufthansa, Brussels Airlines and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Mainz and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Budenheim or to Saint-Gilles, and look at flights from Frankfurt am Main Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Mainz to Brussels?
The most popular companies between Mainz and Brussels, are Lufthansa, Brussels Airlines and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and BlaBlaCar Bus
Train companies: Deutsche Bahn
Airlines: Lufthansa, Brussels Airlines, Eurowings and 3 more.
All you need to know when you travel from Mainz to Brussels
Check all information on comfort and services on all modes of transports from Mainz to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Mainz to Brussels
How can I reach Brussels from Mainz?
Every day, there are on average 8 connections between Flight, Train and Bus, with which you can get to Brussels from Mainz.
How far is Brussels from Mainz?
The distance between Mainz and Brussels is 291.9 km.
What is the most ecofriendly mode of transport between Mainz and Brussels?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 8 kgs of CO2, a train 10 kgs, a car 50 kgs, and a flight 72 kgs.
What is the cheapest mode of transport from Mainz to Brussels?
You can get to Brussels with just £17 by taking a Bus from FlixBus.
What is the fastest way to get from Mainz to Brussels?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 1h 0m with a Flight from Lufthansa.
More routes to Mainz and to Brussels
Looking for more options? Here you can see the most popular routes to Mainz and to Brussels. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Mainz
- Berlin to Mainz
- Bremen to Mainz
- Brussels to Mainz
- Dresden to Mainz
- Frankfurt am Main Airport to Mainz
- Frankfurt Hahn Airport to Mainz
- Freiburg to Mainz
- Kaiserslautern to Mainz
- Koblenz to Mainz
- Munich to Mainz
- Saarbruecken to Mainz
- Simmern (Hunsrück) to Mainz
- The Hague to Mainz
- Trips to Brussels
- Amsterdam to Brussels
- Barcelona to Brussels
- Basel to Brussels
- Berlin to Brussels
- Birmingham to Brussels
- Bologna to Brussels
- Bordeaux to Brussels
- Brussels South Charleroi Airport to Brussels
- Carcassonne to Brussels
- Cologne/Bonn Airport to Brussels
- Edinburgh to Brussels
- Lille to Brussels
- Lisbon to Brussels
- London to Brussels
- Lucerne to Brussels
- Lyon to Brussels
- Milan to Brussels
- Newcastle upon Tyne to Brussels
- Nottingham to Brussels
- Paris to Brussels
- Salzburg to Brussels
- The Hague to Brussels
- Vienna to Brussels
- Zurich to Brussels
