What is the best way to travel from Mainz to Brussels?
Looking for a trip? Check and compare all the available Flights, Trains and Buses to Brussels from Mainz. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Brussels from Mainz?
You can reach Brussels with just £21 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Deutsche Bahn4h 55m019:20MainzCentral Station00:15BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Mainz (Germany) at 04/05/2026 19:20:00 to Central Station, Brussels (Belgium) arriving at 05/05/2026 00:15:00. 50 Economy ticket for £33 per person are available. Travel duration is 4h 55m
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Deutsche Bahn2h 56m006:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station09:44BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 04/05/2026 06:48:00 to Central Station, Brussels (Belgium) arriving at 04/05/2026 09:44:00. 50 Economy ticket for £55 per person are available. Travel duration is 2h 56m
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Deutsche Bahn3h 27m006:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station10:15BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 04/05/2026 06:48:00 to Central Station, Brussels (Belgium) arriving at 04/05/2026 10:15:00. 50 Economy ticket for £55 per person are available. Travel duration is 3h 27m
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Deutsche Bahn3h 46m005:58MainzCentral Station09:44BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Mainz (Germany) at 04/05/2026 05:58:00 to Central Station, Brussels (Belgium) arriving at 04/05/2026 09:44:00. 50 Economy ticket for £62 per person are available. Travel duration is 3h 46m
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Lufthansa1h 0m006:45Frankfurt am Main AirportFrankfurt am Main Airport07:45Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/05/2026 06:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/05/2026 07:45:00. 50 Economy ticket for £155 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:40Frankfurt am Main AirportFrankfurt am Main Airport12:45Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/05/2026 11:40:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/05/2026 12:45:00. 50 Economy ticket for £155 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 10m012:30Frankfurt am Main AirportFrankfurt am Main Airport13:40Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/05/2026 12:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/05/2026 13:40:00. 50 Economy ticket for £155 per person are available. Travel duration is 1h 10m
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Brussels Airlines1h 5m016:25Frankfurt am Main AirportFrankfurt am Main Airport17:30Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/05/2026 16:25:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/05/2026 17:30:00. 50 Economy ticket for £155 per person are available. Travel duration is 1h 5m
Cheapest Trains Monday
Cheapest Flights Monday
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FlixBus5h 45m012:20MainzCentral Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 05/05/2026 12:20:00 to North Station, Brussels (Belgium) arriving at 05/05/2026 18:05:00. 50 Economy ticket for £21 per person are available. Travel duration is 5h 45m
Cheapest Buses Tuesday
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Brussels Airlines1h 5m011:40Frankfurt am Main AirportFrankfurt am Main Airport12:45Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/05/2026 11:40:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 06/05/2026 12:45:00. 50 Economy ticket for £266 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 10m012:30Frankfurt am Main AirportFrankfurt am Main Airport13:40Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/05/2026 12:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 06/05/2026 13:40:00. 50 Economy ticket for £266 per person are available. Travel duration is 1h 10m
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Brussels Airlines1h 5m021:30Frankfurt am Main AirportFrankfurt am Main Airport22:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/05/2026 21:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 06/05/2026 22:35:00. 50 Economy ticket for £266 per person are available. Travel duration is 1h 5m
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Lufthansa1h 0m006:45Frankfurt am Main AirportFrankfurt am Main Airport07:45Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/05/2026 06:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 06/05/2026 07:45:00. 50 Economy ticket for £281 per person are available. Travel duration is 1h 0m
Cheapest Flights Wednesday
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FlixBus6h 55m000:25Frankfurt am Main AirportFrankfurt am Main Airport07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 00:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 08/05/2026 07:20:00. 50 Economy ticket for £23 per person are available. Travel duration is 6h 55m
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FlixBus7h 20m006:35Frankfurt am Main AirportFrankfurt am Main Airport13:55BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 06:35:00 to Midi Bus Station, Brussels (Belgium) arriving at 08/05/2026 13:55:00. 50 Economy ticket for £23 per person are available. Travel duration is 7h 20m
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FlixBus6h 55m003:20Frankfurt am Main AirportFrankfurt am Main Airport10:15BrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 03:20:00 to North Station, Brussels (Belgium) arriving at 08/05/2026 10:15:00. 50 Economy ticket for £25 per person are available. Travel duration is 6h 55m
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FlixBus8h 5m006:35Frankfurt am Main AirportFrankfurt am Main Airport14:40BrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 06:35:00 to North Station, Brussels (Belgium) arriving at 08/05/2026 14:40:00. 50 Economy ticket for £32 per person are available. Travel duration is 8h 5m
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Deutsche Bahn3h 27m006:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station10:15BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 08/05/2026 06:48:00 to Central Station, Brussels (Belgium) arriving at 08/05/2026 10:15:00. 50 Economy ticket for £55 per person are available. Travel duration is 3h 27m
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Deutsche Bahn2h 56m006:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station09:44BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 08/05/2026 06:48:00 to Central Station, Brussels (Belgium) arriving at 08/05/2026 09:44:00. 50 Economy ticket for £55 per person are available. Travel duration is 2h 56m
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Deutsche Bahn2h 56m008:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station11:44BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 08/05/2026 08:48:00 to Central Station, Brussels (Belgium) arriving at 08/05/2026 11:44:00. 50 Economy ticket for £79 per person are available. Travel duration is 2h 56m
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Lufthansa1h 0m006:45Frankfurt am Main AirportFrankfurt am Main Airport07:45Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 06:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/05/2026 07:45:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:40Frankfurt am Main AirportFrankfurt am Main Airport12:45Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 11:40:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/05/2026 12:45:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 10m012:30Frankfurt am Main AirportFrankfurt am Main Airport13:40Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 12:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/05/2026 13:40:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 10m
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Brussels Airlines1h 5m016:25Frankfurt am Main AirportFrankfurt am Main Airport17:30Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 16:25:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/05/2026 17:30:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 5m
Cheapest Buses Friday
Cheapest Trains Friday
Cheapest Flights Friday
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FlixBus5h 45m012:20MainzCentral Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 09/05/2026 12:20:00 to North Station, Brussels (Belgium) arriving at 09/05/2026 18:05:00. 50 Economy ticket for £23 per person are available. Travel duration is 5h 45m
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Lufthansa1h 0m006:45Frankfurt am Main AirportFrankfurt am Main Airport07:45Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 06:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 09/05/2026 07:45:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 10m012:30Frankfurt am Main AirportFrankfurt am Main Airport13:40Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 12:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 09/05/2026 13:40:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 10m
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Brussels Airlines1h 5m016:25Frankfurt am Main AirportFrankfurt am Main Airport17:30Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 16:25:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 09/05/2026 17:30:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m019:35Frankfurt am Main AirportFrankfurt am Main Airport20:40Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 19:35:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 09/05/2026 20:40:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 5m
Cheapest Buses Saturday
Cheapest Flights Saturday
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FlixBus7h 20m006:35Frankfurt am Main AirportFrankfurt am Main Airport13:55BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 06:35:00 to Midi Bus Station, Brussels (Belgium) arriving at 10/05/2026 13:55:00. 50 Economy ticket for £23 per person are available. Travel duration is 7h 20m
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FlixBus6h 55m000:25Frankfurt am Main AirportFrankfurt am Main Airport07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 00:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 10/05/2026 07:20:00. 50 Economy ticket for £24 per person are available. Travel duration is 6h 55m
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FlixBus6h 55m003:20Frankfurt am Main AirportFrankfurt am Main Airport10:15BrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 03:20:00 to North Station, Brussels (Belgium) arriving at 10/05/2026 10:15:00. 50 Economy ticket for £24 per person are available. Travel duration is 6h 55m
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FlixBus5h 45m012:20MainzCentral Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 10/05/2026 12:20:00 to North Station, Brussels (Belgium) arriving at 10/05/2026 18:05:00. 50 Economy ticket for £25 per person are available. Travel duration is 5h 45m
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Brussels Airlines1h 5m011:40Frankfurt am Main AirportFrankfurt am Main Airport12:45Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 11:40:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 10/05/2026 12:45:00. 50 Economy ticket for £229 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m016:25Frankfurt am Main AirportFrankfurt am Main Airport17:30Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 16:25:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 10/05/2026 17:30:00. 50 Economy ticket for £229 per person are available. Travel duration is 1h 5m
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Condor7h 50m004:45Frankfurt am Main AirportFrankfurt am Main Airport12:35Antwerp AirportAntwerp Airport0EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 04:45:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 10/05/2026 12:35:00. 50 Economy ticket for £260 per person are available. Travel duration is 7h 50m
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Lufthansa6h 40m005:55Frankfurt am Main AirportFrankfurt am Main Airport12:35Antwerp AirportAntwerp Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 05:55:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 10/05/2026 12:35:00. 50 Economy ticket for £271 per person are available. Travel duration is 6h 40m
Cheapest Buses Sunday
Cheapest Flights Sunday
What are the fastest trips from Mainz to Brussels?
You can get to Brussels from Mainz in just 1h 0m with a Flight from Lufthansa. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Lufthansa1h 0m006:45Frankfurt am Main AirportFrankfurt am Main Airport07:45Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/05/2026 06:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/05/2026 07:45:00. 50 Economy ticket for £155 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:40Frankfurt am Main AirportFrankfurt am Main Airport12:45Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/05/2026 11:40:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/05/2026 12:45:00. 50 Economy ticket for £155 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m016:25Frankfurt am Main AirportFrankfurt am Main Airport17:30Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/05/2026 16:25:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/05/2026 17:30:00. 50 Economy ticket for £155 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m011:40Frankfurt am Main AirportFrankfurt am Main Airport12:45Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 04/05/2026 11:40:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 04/05/2026 12:45:00. 50 Economy ticket for £192 per person are available. Travel duration is 1h 5m
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Deutsche Bahn2h 56m006:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station09:44BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 04/05/2026 06:48:00 to Central Station, Brussels (Belgium) arriving at 04/05/2026 09:44:00. 50 Economy ticket for £55 per person are available. Travel duration is 2h 56m
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Deutsche Bahn3h 27m006:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station10:15BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 04/05/2026 06:48:00 to Central Station, Brussels (Belgium) arriving at 04/05/2026 10:15:00. 50 Economy ticket for £55 per person are available. Travel duration is 3h 27m
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Deutsche Bahn3h 46m005:58MainzCentral Station09:44BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Mainz (Germany) at 04/05/2026 05:58:00 to Central Station, Brussels (Belgium) arriving at 04/05/2026 09:44:00. 50 Economy ticket for £62 per person are available. Travel duration is 3h 46m
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Deutsche Bahn4h 55m019:20MainzCentral Station00:15BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Mainz (Germany) at 04/05/2026 19:20:00 to Central Station, Brussels (Belgium) arriving at 05/05/2026 00:15:00. 50 Economy ticket for £33 per person are available. Travel duration is 4h 55m
Fastest Flights Monday
Fastest Trains Monday
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FlixBus5h 45m012:20MainzCentral Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 05/05/2026 12:20:00 to North Station, Brussels (Belgium) arriving at 05/05/2026 18:05:00. 50 Economy ticket for £21 per person are available. Travel duration is 5h 45m
Fastest Buses Tuesday
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Lufthansa1h 0m006:45Frankfurt am Main AirportFrankfurt am Main Airport07:45Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/05/2026 06:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 06/05/2026 07:45:00. 50 Economy ticket for £281 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:40Frankfurt am Main AirportFrankfurt am Main Airport12:45Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/05/2026 11:40:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 06/05/2026 12:45:00. 50 Economy ticket for £266 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m021:30Frankfurt am Main AirportFrankfurt am Main Airport22:35Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/05/2026 21:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 06/05/2026 22:35:00. 50 Economy ticket for £266 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 10m012:30Frankfurt am Main AirportFrankfurt am Main Airport13:40Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 06/05/2026 12:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 06/05/2026 13:40:00. 50 Economy ticket for £266 per person are available. Travel duration is 1h 10m
Fastest Flights Wednesday
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Lufthansa1h 0m006:45Frankfurt am Main AirportFrankfurt am Main Airport07:45Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 06:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/05/2026 07:45:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:40Frankfurt am Main AirportFrankfurt am Main Airport12:45Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 11:40:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/05/2026 12:45:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m016:25Frankfurt am Main AirportFrankfurt am Main Airport17:30Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 16:25:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/05/2026 17:30:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m011:40Frankfurt am Main AirportFrankfurt am Main Airport12:45Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 11:40:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 08/05/2026 12:45:00. 50 Economy ticket for £192 per person are available. Travel duration is 1h 5m
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Deutsche Bahn2h 56m006:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station09:44BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 08/05/2026 06:48:00 to Central Station, Brussels (Belgium) arriving at 08/05/2026 09:44:00. 50 Economy ticket for £55 per person are available. Travel duration is 2h 56m
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Deutsche Bahn2h 56m008:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station11:44BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 08/05/2026 08:48:00 to Central Station, Brussels (Belgium) arriving at 08/05/2026 11:44:00. 50 Economy ticket for £79 per person are available. Travel duration is 2h 56m
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Deutsche Bahn3h 27m006:48Frankfurt am Main AirportFrankfurt am Main Airport Train Station10:15BrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 08/05/2026 06:48:00 to Central Station, Brussels (Belgium) arriving at 08/05/2026 10:15:00. 50 Economy ticket for £55 per person are available. Travel duration is 3h 27m
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FlixBus6h 55m000:25Frankfurt am Main AirportFrankfurt am Main Airport07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 00:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 08/05/2026 07:20:00. 50 Economy ticket for £23 per person are available. Travel duration is 6h 55m
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FlixBus6h 55m003:20Frankfurt am Main AirportFrankfurt am Main Airport10:15BrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 03:20:00 to North Station, Brussels (Belgium) arriving at 08/05/2026 10:15:00. 50 Economy ticket for £25 per person are available. Travel duration is 6h 55m
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FlixBus7h 20m006:35Frankfurt am Main AirportFrankfurt am Main Airport13:55BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 06:35:00 to Midi Bus Station, Brussels (Belgium) arriving at 08/05/2026 13:55:00. 50 Economy ticket for £23 per person are available. Travel duration is 7h 20m
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FlixBus8h 5m006:35Frankfurt am Main AirportFrankfurt am Main Airport14:40BrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 08/05/2026 06:35:00 to North Station, Brussels (Belgium) arriving at 08/05/2026 14:40:00. 50 Economy ticket for £32 per person are available. Travel duration is 8h 5m
Fastest Flights Friday
Fastest Trains Friday
Fastest Buses Friday
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Lufthansa1h 0m006:45Frankfurt am Main AirportFrankfurt am Main Airport07:45Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 06:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 09/05/2026 07:45:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m016:25Frankfurt am Main AirportFrankfurt am Main Airport17:30Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 16:25:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 09/05/2026 17:30:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m019:35Frankfurt am Main AirportFrankfurt am Main Airport20:40Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 19:35:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 09/05/2026 20:40:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 10m012:30Frankfurt am Main AirportFrankfurt am Main Airport13:40Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 09/05/2026 12:30:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 09/05/2026 13:40:00. 50 Economy ticket for £156 per person are available. Travel duration is 1h 10m
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FlixBus5h 45m012:20MainzCentral Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 09/05/2026 12:20:00 to North Station, Brussels (Belgium) arriving at 09/05/2026 18:05:00. 50 Economy ticket for £23 per person are available. Travel duration is 5h 45m
Fastest Flights Saturday
Fastest Buses Saturday
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Lufthansa1h 0m006:45Frankfurt am Main AirportFrankfurt am Main Airport07:45Brussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 06:45:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 10/05/2026 07:45:00. 50 Economy ticket for £284 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:40Frankfurt am Main AirportFrankfurt am Main Airport12:45Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 11:40:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 10/05/2026 12:45:00. 50 Economy ticket for £229 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m016:25Frankfurt am Main AirportFrankfurt am Main Airport17:30Brussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 16:25:00 to Brussels Airport, Brussels Airport (Belgium) arriving at 10/05/2026 17:30:00. 50 Economy ticket for £229 per person are available. Travel duration is 1h 5m
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Condor5h 55m006:40Frankfurt am Main AirportFrankfurt am Main Airport12:35Antwerp AirportAntwerp Airport0EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 06:40:00 to Antwerp Airport, Antwerp Airport (Belgium) arriving at 10/05/2026 12:35:00. 50 Economy ticket for £282 per person are available. Travel duration is 5h 55m
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FlixBus5h 45m012:20MainzCentral Station18:05BrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 10/05/2026 12:20:00 to North Station, Brussels (Belgium) arriving at 10/05/2026 18:05:00. 50 Economy ticket for £25 per person are available. Travel duration is 5h 45m
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FlixBus6h 55m000:25Frankfurt am Main AirportFrankfurt am Main Airport07:20BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 00:25:00 to Midi Bus Station, Brussels (Belgium) arriving at 10/05/2026 07:20:00. 50 Economy ticket for £24 per person are available. Travel duration is 6h 55m
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FlixBus6h 55m003:20Frankfurt am Main AirportFrankfurt am Main Airport10:15BrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 03:20:00 to North Station, Brussels (Belgium) arriving at 10/05/2026 10:15:00. 50 Economy ticket for £24 per person are available. Travel duration is 6h 55m
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FlixBus7h 20m006:35Frankfurt am Main AirportFrankfurt am Main Airport13:55BrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 10/05/2026 06:35:00 to Midi Bus Station, Brussels (Belgium) arriving at 10/05/2026 13:55:00. 50 Economy ticket for £23 per person are available. Travel duration is 7h 20m
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Here you will find all operators and timetables for a
Bus from Mainz to Brussels
What are the most popular stations in Mainz and Brussels?
In Mainz, you will usually depart from Laubenheim Train Station, Central Bus Station or Central Station, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brussels from Mainz? With 9 connections between 2 Flight, Bus and Train operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Mainz and Brussels, you can pay as low as £21 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Lufthansa: you will get to Brussels in just 1h 0m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Mainz and Brussels are Lufthansa, Brussels Airlines and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Mainz and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Budenheim or to Saint-Gilles, and look at flights from Frankfurt am Main Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Mainz to Brussels?
The most popular companies between Mainz and Brussels, are Lufthansa, Brussels Airlines and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Train companies: Deutsche Bahn
Airlines: Lufthansa, Brussels Airlines, Condor and 1 more.
All you need to know when you travel from Mainz to Brussels
Check all information on comfort and services on all modes of transports from Mainz to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Mainz to Brussels
How can I reach Brussels from Mainz?
Every day, there are on average 9 connections between Flight, Bus and Train, with which you can get to Brussels from Mainz.
How far is Brussels from Mainz?
The distance between Mainz and Brussels is 291.9 km.
What is the most ecofriendly mode of transport between Mainz and Brussels?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 8 kgs of CO2, a train 10 kgs, a car 50 kgs, and a flight 72 kgs.
What is the cheapest mode of transport from Mainz to Brussels?
You can get to Brussels with just £21 by taking a Bus from FlixBus.
What is the fastest way to get from Mainz to Brussels?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 1h 0m with a Flight from Lufthansa.
More routes to Mainz and to Brussels
Looking for more options? Here you can see the most popular routes to Mainz and to Brussels. Simply click on a connection, and you’ll find all the details about the route!
