Which bus from Lyon to Milan is the best?
Check the bus schedule for Lyon to Milan. Here is a selection of the cheapest coach trips for the next days from bus operators like Itabus, FlixBus or BlaBlaCar Bus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 6h 55m | 05:10 | Lyon | Perrache Train Station | 12:05 | Milan | Lampugnano Bus Station | Economy | £16 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 21/03/2026 05:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 21/03/2026 12:05:00. 50 Economy ticket for £16 per person are available. Travel duration is 6h 55m
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| BlaBlaCar Bus | 6h 30m | 23:30 | Lyon | Perrache Train Station | 06:00 | Milan | Lampugnano Bus Station | Economy | £17 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 21/03/2026 23:30:00 to Lampugnano Bus Station, Milan (Italy) arriving at 22/03/2026 06:00:00. 50 Economy ticket for £17 per person are available. Travel duration is 6h 30m
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| Itabus | 6h 40m | 05:40 | Lyon | Perrache Bus Stop | 12:20 | Milan | Lampugnano Bus Station | Premium Economy | £17 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 21/03/2026 05:40:00 to Lampugnano Bus Station, Milan (Italy) arriving at 21/03/2026 12:20:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 6h 40m
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| Itabus | 6h 25m | 23:50 | Lyon | Perrache Bus Stop | 06:15 | Milan | Lampugnano Bus Station | Premium Economy | £17 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 21/03/2026 23:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 22/03/2026 06:15:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 6h 25m
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| FlixBus | 6h 40m | 10:45 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 17:25 | Milan | Lampugnano Bus Station | Economy | £28 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 21/03/2026 10:45:00 to Lampugnano Bus Station, Milan (Italy) arriving at 21/03/2026 17:25:00. 50 Economy ticket for £28 per person are available. Travel duration is 6h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 6h 40m | 05:40 | Lyon | Perrache Bus Stop | 12:20 | Milan | Lampugnano Bus Station | Premium Economy | £17 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 22/03/2026 05:40:00 to Lampugnano Bus Station, Milan (Italy) arriving at 22/03/2026 12:20:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 6h 40m
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| Itabus | 6h 25m | 23:50 | Lyon | Perrache Bus Stop | 06:15 | Milan | Lampugnano Bus Station | Premium Economy | £17 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 22/03/2026 23:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 23/03/2026 06:15:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 6h 25m
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| BlaBlaCar Bus | 7h 5m | 07:00 | Lyon | Perrache Train Station | 14:05 | Milan | Lampugnano Bus Station | Economy | £20 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 22/03/2026 07:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 22/03/2026 14:05:00. 50 Economy ticket for £20 per person are available. Travel duration is 7h 5m
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| BlaBlaCar Bus | 6h 11m | 23:59 | Lyon | Perrache Train Station | 06:10 | Milan | Lampugnano Bus Station | Economy | £22 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 22/03/2026 23:59:00 to Lampugnano Bus Station, Milan (Italy) arriving at 23/03/2026 06:10:00. 50 Economy ticket for £22 per person are available. Travel duration is 6h 11m
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| FlixBus | 6h 25m | 00:05 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 06:30 | Milan | Lampugnano Bus Station | Economy | £30 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 22/03/2026 00:05:00 to Lampugnano Bus Station, Milan (Italy) arriving at 22/03/2026 06:30:00. 50 Economy ticket for £30 per person are available. Travel duration is 6h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 6h 55m | 05:10 | Lyon | Perrache Train Station | 12:05 | Milan | Lampugnano Bus Station | Economy | £16 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 23/03/2026 05:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 23/03/2026 12:05:00. 50 Economy ticket for £16 per person are available. Travel duration is 6h 55m
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| BlaBlaCar Bus | 7h 5m | 07:00 | Lyon | Perrache Train Station | 14:05 | Milan | Lampugnano Bus Station | Economy | £17 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 23/03/2026 07:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 23/03/2026 14:05:00. 50 Economy ticket for £17 per person are available. Travel duration is 7h 5m
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| Itabus | 6h 40m | 05:40 | Lyon | Perrache Bus Stop | 12:20 | Milan | Lampugnano Bus Station | Premium Economy | £17 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 23/03/2026 05:40:00 to Lampugnano Bus Station, Milan (Italy) arriving at 23/03/2026 12:20:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 6h 40m
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| Itabus | 6h 25m | 23:50 | Lyon | Perrache Bus Stop | 06:15 | Milan | Lampugnano Bus Station | Premium Economy | £17 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 23/03/2026 23:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 24/03/2026 06:15:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 6h 25m
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| FlixBus | 6h 40m | 10:45 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 17:25 | Milan | Lampugnano Bus Station | Economy | £21 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 10:45:00 to Lampugnano Bus Station, Milan (Italy) arriving at 23/03/2026 17:25:00. 50 Economy ticket for £21 per person are available. Travel duration is 6h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 6h 55m | 05:10 | Lyon | Perrache Train Station | 12:05 | Milan | Lampugnano Bus Station | Economy | £15 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 24/03/2026 05:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 24/03/2026 12:05:00. 50 Economy ticket for £15 per person are available. Travel duration is 6h 55m
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| BlaBlaCar Bus | 7h 5m | 07:00 | Lyon | Perrache Train Station | 14:05 | Milan | Lampugnano Bus Station | Economy | £15 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 24/03/2026 07:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 24/03/2026 14:05:00. 50 Economy ticket for £15 per person are available. Travel duration is 7h 5m
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| Itabus | 6h 40m | 05:40 | Lyon | Perrache Bus Stop | 12:20 | Milan | Lampugnano Bus Station | Basic | £15 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 24/03/2026 05:40:00 to Lampugnano Bus Station, Milan (Italy) arriving at 24/03/2026 12:20:00. 50 Basic ticket for £15 per person are available. Travel duration is 6h 40m
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| FlixBus | 7h 5m | 06:15 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 13:20 | Milan | Lampugnano Bus Station | Economy | £17 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 06:15:00 to Lampugnano Bus Station, Milan (Italy) arriving at 24/03/2026 13:20:00. 50 Economy ticket for £17 per person are available. Travel duration is 7h 5m
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| Itabus | 6h 50m | 15:30 | Lyon | Perrache Bus Stop | 22:20 | Milan | Lampugnano Bus Station | Premium Economy | £17 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 24/03/2026 15:30:00 to Lampugnano Bus Station, Milan (Italy) arriving at 24/03/2026 22:20:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 6h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 6h 50m | 15:30 | Lyon | Perrache Bus Stop | 22:20 | Milan | Lampugnano Bus Station | Premium Economy | £15 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 25/03/2026 15:30:00 to Lampugnano Bus Station, Milan (Italy) arriving at 25/03/2026 22:20:00. 50 Premium Economy ticket for £15 per person are available. Travel duration is 6h 50m
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| Union Ivkoni | 9h 0m | 08:00 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 17:00 | Milan | Lampugnano Bus Station | Basic | £16 |
A Bus from Union Ivkoni goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 25/03/2026 08:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 25/03/2026 17:00:00. 50 Basic ticket for £16 per person are available. Travel duration is 9h 0m
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| FlixBus | 7h 0m | 14:55 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 21:55 | Milan | Lampugnano Bus Station | Economy | £20 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 25/03/2026 14:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 25/03/2026 21:55:00. 50 Economy ticket for £20 per person are available. Travel duration is 7h 0m
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| FlixBus | 6h 25m | 00:05 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 06:30 | Milan | Lampugnano Bus Station | Economy | £21 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 25/03/2026 00:05:00 to Lampugnano Bus Station, Milan (Italy) arriving at 25/03/2026 06:30:00. 50 Economy ticket for £21 per person are available. Travel duration is 6h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 6h 35m | 09:15 | Lyon | Perrache Bus Stop | 15:50 | Milan | Lampugnano Bus Station | Basic | £16 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 26/03/2026 09:15:00 to Lampugnano Bus Station, Milan (Italy) arriving at 26/03/2026 15:50:00. 50 Basic ticket for £16 per person are available. Travel duration is 6h 35m
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| FlixBus | 7h 5m | 06:15 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 13:20 | Milan | Lampugnano Bus Station | Economy | £21 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 06:15:00 to Lampugnano Bus Station, Milan (Italy) arriving at 26/03/2026 13:20:00. 50 Economy ticket for £21 per person are available. Travel duration is 7h 5m
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| FlixBus | 6h 40m | 10:45 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 17:25 | Milan | Lampugnano Bus Station | Economy | £21 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 10:45:00 to Lampugnano Bus Station, Milan (Italy) arriving at 26/03/2026 17:25:00. 50 Economy ticket for £21 per person are available. Travel duration is 6h 40m
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| FlixBus | 6h 20m | 12:45 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 19:05 | Milan | Lampugnano Bus Station | Economy | £21 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 12:45:00 to Lampugnano Bus Station, Milan (Italy) arriving at 26/03/2026 19:05:00. 50 Economy ticket for £21 per person are available. Travel duration is 6h 20m
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| Itabus | 6h 50m | 15:30 | Lyon | Perrache Bus Stop | 22:20 | Milan | Lampugnano Bus Station | Premium Economy | £26 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 26/03/2026 15:30:00 to Lampugnano Bus Station, Milan (Italy) arriving at 26/03/2026 22:20:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 6h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 6h 30m | 23:30 | Lyon | Perrache Train Station | 06:00 | Milan | Lampugnano Bus Station | Economy | £17 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 27/03/2026 23:30:00 to Lampugnano Bus Station, Milan (Italy) arriving at 28/03/2026 06:00:00. 50 Economy ticket for £17 per person are available. Travel duration is 6h 30m
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| BlaBlaCar Bus | 6h 11m | 23:59 | Lyon | Perrache Train Station | 06:10 | Milan | Lampugnano Bus Station | Economy | £17 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 27/03/2026 23:59:00 to Lampugnano Bus Station, Milan (Italy) arriving at 28/03/2026 06:10:00. 50 Economy ticket for £17 per person are available. Travel duration is 6h 11m
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| Itabus | 6h 25m | 23:50 | Lyon | Perrache Bus Stop | 06:15 | Milan | Lampugnano Bus Station | Premium Economy | £18 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 27/03/2026 23:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 28/03/2026 06:15:00. 50 Premium Economy ticket for £18 per person are available. Travel duration is 6h 25m
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| FlixBus | 6h 25m | 00:05 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 06:30 | Milan | Lampugnano Bus Station | Economy | £22 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 00:05:00 to Lampugnano Bus Station, Milan (Italy) arriving at 27/03/2026 06:30:00. 50 Economy ticket for £22 per person are available. Travel duration is 6h 25m
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| FlixBus | 6h 25m | 23:00 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 05:25 | Milan | Lampugnano Bus Station | Economy | £22 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 23:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 28/03/2026 05:25:00. 50 Economy ticket for £22 per person are available. Travel duration is 6h 25m
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Best Price Offer: The price for the cheapest coach from Lyon to Milan is £15 on 24/03/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Lyon and Milan?
All facts for Lyon to Milan bus at a glance
Compare all coach operators like Itabus, FlixBus and BlaBlaCar Bus that travel daily 26 times by bus from Lyon to Milan in one click. Book your Lyon to Milan bus ticket starting from £15!
| Cheapest Bus | £15 |
| Fastest Bus | 6h 5m |
| Earliest Coach | 00:05 |
| Latest Coach | 23:59 |
| Daily Bus Connections | 26 Ø |
| Distance | 339.9 km |
| Coach Companies | Itabus, FlixBus, BlaBlaCar Bus and Union Ivkoni |
What are the cheapest coach tickets from Lyon to Milan?
Every day, 26 buses from 4 coach companies leave Lyon for Milan. Check the table below to find the cheapest prices for coach tickets for this route, starting from 21/03/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Lyon to Milan
How to save money travelling from Lyon to Milan
Book the ticket from Lyon to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Lyon to Milan, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Lyon to Milan are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
What are the most popular bus companies from Lyon to Milan?
Itabus from Lyon to Milan
Here you will find the key facts about the Itabus bus route Lyon to Milan:
| Cheapest Price | £15 |
| Fastest Coach | 6h 25m |
| Earliest Coach | 05:40 |
| Last Coach | 23:50 |
| Daily Connections | 12 Ø |
| Found on | 20/03/2026 |
Latest reviews for coach companies on the route Lyon - Milan
All bus stations and stops in Lyon and Milan
Here is a map with all coach stations in Lyon and Milan. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Lyon to Milan
FAQs for Lyon to Milan bus
How much does a Lyon Milan coach trip cost?
How much could I save by comparing buses from Lyon to Milan?
How many connections are available for the Lyon Milan route on average every day?
How long does a bus to Milan from Lyon take?
What time is the first bus from Lyon to Milan?
What time is the last coach from Lyon to Milan?
Which bus companies serve the Lyon Milan route?
Is there a direct bus between Lyon and Milan?
What can I take with me on the bus to Milan from Lyon?
What equipment is available for the Lyon Milan bus route?
How does CheckMyBus find the best coach deals from Lyon to Milan?
How does CheckMyBus technology work for trips from Lyon to Milan?
Available seat classes which are offered on the bus route Lyon to Milan
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
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