Compare all timetables for the bus from Siena to Milan
Here is a selection of the cheapest bus trips from the schedule from Siena to Milan from various bus operators like Itabus or FlixBus for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 5h 45m | 10:55 | Siena | Central Bus Station | 16:40 | Milan | Lampugnano Bus Station | Basic | £8 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 08/05/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 08/05/2026 16:40:00. 50 Basic ticket for £8 per person are available. Travel duration is 5h 45m
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| Itabus | 5h 10m | 17:55 | Siena | Central Bus Station | 23:05 | Milan | San Donato Bus Station | Basic | £9 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 08/05/2026 17:55:00 to San Donato Bus Station, Milan (Italy) arriving at 08/05/2026 23:05:00. 50 Basic ticket for £9 per person are available. Travel duration is 5h 10m
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| Itabus | 4h 55m | 13:55 | Siena | Central Bus Station | 18:50 | Milan | San Donato Bus Station | Basic | £15 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 08/05/2026 13:55:00 to San Donato Bus Station, Milan (Italy) arriving at 08/05/2026 18:50:00. 50 Basic ticket for £15 per person are available. Travel duration is 4h 55m
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| Itabus | 5h 50m | 01:05 | Siena | Train Station | 06:55 | Milan | Lampugnano Bus Station | Premium Economy | £17 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 08/05/2026 01:05:00 to Lampugnano Bus Station, Milan (Italy) arriving at 08/05/2026 06:55:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 5h 50m
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| Itabus | 7h 30m | 13:55 | Siena | Train Station | 21:25 | Milan | Lampugnano Bus Station | Premium Economy | £18 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 08/05/2026 13:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 08/05/2026 21:25:00. 50 Premium Economy ticket for £18 per person are available. Travel duration is 7h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 5h 55m | 07:50 | Siena | Train Station | 13:45 | Milan | Lampugnano Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 09/05/2026 07:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 09/05/2026 13:45:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 55m
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| FlixBus | 6h 10m | 17:25 | Siena | Train Station | 23:35 | Milan | Lampugnano Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 09/05/2026 17:25:00 to Lampugnano Bus Station, Milan (Italy) arriving at 09/05/2026 23:35:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 10m
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| FlixBus | 5h 19m | 18:40 | Siena | Train Station | 23:59 | Milan | Lampugnano Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 09/05/2026 18:40:00 to Lampugnano Bus Station, Milan (Italy) arriving at 09/05/2026 23:59:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 19m
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| Itabus | 4h 55m | 13:55 | Siena | Central Bus Station | 18:50 | Milan | San Donato Bus Station | Basic | £12 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 09/05/2026 13:55:00 to San Donato Bus Station, Milan (Italy) arriving at 09/05/2026 18:50:00. 50 Basic ticket for £12 per person are available. Travel duration is 4h 55m
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| Itabus | 5h 10m | 17:55 | Siena | Central Bus Station | 23:05 | Milan | San Donato Bus Station | Basic | £12 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 09/05/2026 17:55:00 to San Donato Bus Station, Milan (Italy) arriving at 09/05/2026 23:05:00. 50 Basic ticket for £12 per person are available. Travel duration is 5h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 5h 50m | 06:10 | Siena | Train Station | 12:00 | Milan | San Donato Bus Station | Economy | £9 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 10/05/2026 06:10:00 to San Donato Bus Station, Milan (Italy) arriving at 10/05/2026 12:00:00. 50 Economy ticket for £9 per person are available. Travel duration is 5h 50m
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| FlixBus | 4h 50m | 06:40 | Siena | Train Station | 11:30 | Milan | San Donato Bus Station | Economy | £9 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 10/05/2026 06:40:00 to San Donato Bus Station, Milan (Italy) arriving at 10/05/2026 11:30:00. 50 Economy ticket for £9 per person are available. Travel duration is 4h 50m
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| FlixBus | 6h 50m | 06:10 | Siena | Train Station | 13:00 | Milan | Lampugnano Bus Station | Economy | £9 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 10/05/2026 06:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 10/05/2026 13:00:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 50m
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| Itabus | 5h 45m | 10:55 | Siena | Train Station | 16:40 | Milan | Lampugnano Bus Station | Premium Economy | £9 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 10/05/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 10/05/2026 16:40:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 5h 45m
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| Itabus | 4h 55m | 13:55 | Siena | Train Station | 18:50 | Milan | San Donato Bus Station | Premium Economy | £9 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 10/05/2026 13:55:00 to San Donato Bus Station, Milan (Italy) arriving at 10/05/2026 18:50:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 4h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 5h 45m | 10:55 | Siena | Central Bus Station | 16:40 | Milan | Lampugnano Bus Station | Economy | £10 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 11/05/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 11/05/2026 16:40:00. 50 Economy ticket for £10 per person are available. Travel duration is 5h 45m
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| Itabus | 4h 55m | 13:55 | Siena | Train Station | 18:50 | Milan | San Donato Bus Station | Premium Economy | £20 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 11/05/2026 13:55:00 to San Donato Bus Station, Milan (Italy) arriving at 11/05/2026 18:50:00. 50 Premium Economy ticket for £20 per person are available. Travel duration is 4h 55m
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| Itabus | 5h 50m | 01:05 | Siena | Train Station | 06:55 | Milan | Lampugnano Bus Station | Premium Economy | £23 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 11/05/2026 01:05:00 to Lampugnano Bus Station, Milan (Italy) arriving at 11/05/2026 06:55:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 5h 50m
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| Itabus | 6h 35m | 01:05 | Siena | Train Station | 07:40 | Milan | San Donato Bus Station | Premium Economy | £45 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 11/05/2026 01:05:00 to San Donato Bus Station, Milan (Italy) arriving at 11/05/2026 07:40:00. 50 Premium Economy ticket for £45 per person are available. Travel duration is 6h 35m
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| Itabus | 6h 0m | 01:05 | Siena | Train Station | 07:05 | Milan | San Donato Bus Station | Premium Economy | £45 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 11/05/2026 01:05:00 to San Donato Bus Station, Milan (Italy) arriving at 11/05/2026 07:05:00. 50 Premium Economy ticket for £45 per person are available. Travel duration is 6h 0m
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Best Price Offer: The price for the cheapest coach from Siena to Milan is £6 on 09/05/2026. Flexible travellers save on ticket prices.
Frequency of bus connections between Siena and Milan
Sunday
is the busiest day, with more than 53 daily coaches from Siena to Milan. Monday has instead the fewest connections, with only 10 daily coaches between Siena and Milan.
The busiest time of the day is the Night, with 48 coaches from Siena to Milan, while Evening sees the fewest connections between Siena and Milan, with 2 offers.
Facts about coaches from Siena to Milan
Compare all providers like Itabus and FlixBus that travel 31 times every day by bus from Siena to Milan in one click! Book your bus ticket from Siena to Milan starting from £6!
| Cheapest Bus | £6 |
| Fastest Bus | 4h 30m |
| Earliest Coach | 01:05 |
| Latest Coach | 13:55 |
| Daily Bus Connections | 31 Ø |
| Distance | 293.3 km |
| Coach Companies | Itabus and FlixBus |
Cheapest coach connections from Siena to Milan
Every day, 31 buses from 2 coach companies leave Siena for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/05/2026 and for the following days.
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday
04/05
Tuesday
05/05
Wednesday
06/05
Thursday
07/05
Friday
08/05
£8
Saturday
09/05
£12
Sunday
10/05
£9
Monday
11/05
£8
Tuesday
12/05
£12
Wednesday
13/05
£8
Thursday
14/05
£9
Friday
15/05
£10
Saturday
16/05
£9
Sunday
17/05
£6
Monday
18/05
£6
Tuesday
19/05
£9
Wednesday
20/05
£9
Thursday
21/05
£6
Friday
22/05
£15
Saturday
23/05
£6
Sunday
24/05
£9
Monday
25/05
£7
Tuesday
26/05
£6
Wednesday
27/05
£6
Thursday
28/05
£11
Friday
29/05
£15
Saturday
30/05
£8
Sunday
31/05
The cheapest time to travel from Siena to Milan
With a price starting from £6, Saturday is the cheapest day for a coach from Siena to Milan. Friday instead is the most expensive day with prices starting from £8.
Night
is the cheapest day time for bus tickets from Siena to Milan, with £6. Morning is the most expensive time of the day with prices starting from £6.
How to save money travelling from Siena to Milan
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Siena to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Siena to Milan, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Siena to Milan are also emptier.All bus stations and stops in Siena and Milan
The map below shows you where to find all the bus stations in Siena and Milan.
Compare the bus with other modes of transport
The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Siena to Milan? Compare all modes of transports from
Siena to Milan.
Service and Comfort on the bus from Siena to Milan
Want to know which seat classes are available on the coaches from Siena to Milan? Or which bus companies serve the route Siena to Milan? Below you will find answers to your questions.
FAQs about the Siena to Milan bus
How much does a Siena - Milan coach trip cost?
This depends on, among other things, the day and travel time. The cheapest ticket for the Siena - Milan bus trip is available from £6 and takes 5h 55m. Compare offers and save money!
How much could I save by comparing buses from Siena to Milan?
The connection Siena to Milan is offered by 2 companies with ticket prices ranging from £6 to £48. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.
How many connections are available for the Siena - Milan route on average every day?
Each day, the bus route from Siena to Milan is offered by roughly 31 busses. By using our search, you can compare bus schedules and find your ideal trip.
How long does a bus to Milan from Siena take?
The quickest coach from Siena to Milan is provided by FlixBus and takes 4h 30m. Coach tickets for this connection cost £9. However, keep in mind that the connection can take longer due to traffic.
What time is the first bus from Siena to Milan?
The earliest bus to Milan departs from Siena at 01:05. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.
What time is the last coach from Siena to Milan?
The latest bus to Milan departs from Siena at 13:55. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.
Which bus companies serve the Siena - Milan route?
Passengers looking to travel from Siena to Milan can travel with Itabus and FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.
Is there a direct bus between Siena and Milan?
You can check all the direct connections between Siena and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Itabus and FlixBus.
What can I take with me on the bus to Milan from Siena?
Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Siena Milan bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.
What equipment is available for the Siena Milan bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Siena to Milan on your planned travel date.
How does CheckMyBus find the best bus deals from Siena to Milan?
CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 31 daily trips between Siena and Milan. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.
How does CheckMyBus technology work for trips from Siena to Milan?
Prices and availability for 31 trips between Siena and Milan change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.
Available seat classes which are offered on the bus route Siena to Milan
Basic
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
Premium Economy
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
More bus routes to Siena and to Milan
Here’s an overview of the most popular bus routes to Siena and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Siena
- Arezzo to Siena coach
- Coach from Avellino to Siena
- Bus Bologna to Siena
- Coach to Siena from Naples
- Perugia to Siena coach
- Bus Pescara to Siena
- Prato to Siena bus
- Bus Rome to Siena
- Sala Consilina to Siena coach
- Bus Routes to Milan
- Coaches Avignon to Milan
- Breuil-Cervinia to Milan bus
- Coach Castrovillari to Milan
- Catania to Milan bus
- Coaches Cosenza to Milan
- Coach to Milan from Courmayeur
- Foggia to Milan coach
- Coaches Lamezia Terme to Milan
- Coach Madrid to Milan
- Matera to Milan coach
- Bus Modena to Milan
- Coach Mulhouse to Milan
- Bus Passo del Tonale to Milan
- Coach to Milan from Porto Garibaldi
- Sanremo to Milan bus
- Coach to Milan from Sibari
- Coach to Milan from Soverato
- Turin to Milan coach
- Bus to Milan from Vibo Valentia
- Bus to Milan from Warsaw
Popular Airport Transfers to Siena and to Milan
