Compare all timetables for the bus from Siena to Milan
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 5h 45m | 10:55 | Siena | Central Bus Station | 16:40 | Milan | Lampugnano Bus Station | Economy | £18 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 01/11/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 01/11/2026 16:40:00. 50 Economy ticket for £18 per person are available. Travel duration is 5h 45m
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| FlixBus | 7h 20m | 14:25 | Siena | Train Station | 21:45 | Milan | Lampugnano Bus Station | Economy | £19 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 01/11/2026 14:25:00 to Lampugnano Bus Station, Milan (Italy) arriving at 01/11/2026 21:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 7h 20m
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| Itabus | 5h 10m | 17:55 | Siena | Central Bus Station | 23:05 | Milan | San Donato Bus Station | Economy | £19 |
A Bus from Itabus goes from Central Bus Station, Siena (Italy) at 01/11/2026 17:55:00 to San Donato Bus Station, Milan (Italy) arriving at 01/11/2026 23:05:00. 50 Economy ticket for £19 per person are available. Travel duration is 5h 10m
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| FlixBus | 5h 19m | 18:40 | Siena | Train Station | 23:59 | Milan | Lampugnano Bus Station | Economy | £20 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 01/11/2026 18:40:00 to Lampugnano Bus Station, Milan (Italy) arriving at 01/11/2026 23:59:00. 50 Economy ticket for £20 per person are available. Travel duration is 5h 19m
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| FlixBus | 5h 15m | 09:20 | Siena | Train Station | 14:35 | Milan | San Donato Bus Station | Economy | £24 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 01/11/2026 09:20:00 to San Donato Bus Station, Milan (Italy) arriving at 01/11/2026 14:35:00. 50 Economy ticket for £24 per person are available. Travel duration is 5h 15m
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FlixBus5h 50m006:10SienaTrain Station10:30ParmaVia Villa Sant'Angelo Coach Station0EconomyA Bus from FlixBus goes from Train Station, Siena (Italy) at 03/11/2026 06:10:00 to Via Villa Sant'Angelo Coach Station, Parma (Italy) arriving at 03/11/2026 10:30:00. 50 Economy ticket for £10 per person are available. Travel duration is 4h 20m
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FlixBus1h 25m010:35ParmaVia Villa Sant'Angelo Coach Station12:00MilanSan Donato Bus Station0EconomyA Bus from FlixBus goes from Via Villa Sant'Angelo Coach Station, Parma (Italy) at 03/11/2026 10:35:00 to San Donato Bus Station, Milan (Italy) arriving at 03/11/2026 12:00:00. 50 Economy ticket for £4 per person are available. Travel duration is 1h 25m
Waiting Time 0h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 5h 45m | 10:55 | Siena | Train Station | 16:40 | Milan | Lampugnano Bus Station | Premium Economy | £12 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 02/11/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 02/11/2026 16:40:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 5h 45m
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| Itabus | 5h 50m | 01:05 | Siena | Train Station | 06:55 | Milan | Lampugnano Bus Station | Premium Economy | £17 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 02/11/2026 01:05:00 to Lampugnano Bus Station, Milan (Italy) arriving at 02/11/2026 06:55:00. 50 Premium Economy ticket for £17 per person are available. Travel duration is 5h 50m
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| Itabus | 7h 5m | 01:05 | Siena | Train Station | 08:10 | Milan | San Donato Bus Station | Premium Economy | £25 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 02/11/2026 01:05:00 to San Donato Bus Station, Milan (Italy) arriving at 02/11/2026 08:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 7h 5m
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| FlixBus | 6h 49m | 14:51 | Siena | Bus Stop | 21:40 | Milan | Lampugnano Bus Station | Economy | £52 |
A Bus from FlixBus goes from Bus Stop, Siena (Italy) at 02/11/2026 14:51:00 to Lampugnano Bus Station, Milan (Italy) arriving at 02/11/2026 21:40:00. 50 Economy ticket for £52 per person are available. Travel duration is 6h 49m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 5h 50m | 06:10 | Siena | Train Station | 12:00 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 03/11/2026 06:10:00 to San Donato Bus Station, Milan (Italy) arriving at 03/11/2026 12:00:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 50m
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| FlixBus | 5h 15m | 06:30 | Siena | Train Station | 11:45 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 03/11/2026 06:30:00 to San Donato Bus Station, Milan (Italy) arriving at 03/11/2026 11:45:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 15m
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| FlixBus | 5h 15m | 09:20 | Siena | Train Station | 14:35 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 03/11/2026 09:20:00 to San Donato Bus Station, Milan (Italy) arriving at 03/11/2026 14:35:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 15m
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| Itabus | 5h 45m | 10:55 | Siena | Train Station | 16:40 | Milan | Lampugnano Bus Station | Premium Economy | £11 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 03/11/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 03/11/2026 16:40:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 5h 45m
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| Itabus | 5h 50m | 01:05 | Siena | Train Station | 06:55 | Milan | Lampugnano Bus Station | Premium Economy | £15 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 03/11/2026 01:05:00 to Lampugnano Bus Station, Milan (Italy) arriving at 03/11/2026 06:55:00. 50 Premium Economy ticket for £15 per person are available. Travel duration is 5h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 5h 45m | 10:55 | Siena | Train Station | 16:40 | Milan | Lampugnano Bus Station | Premium Economy | £7 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 04/11/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 04/11/2026 16:40:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 5h 45m
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| Itabus | 5h 50m | 01:05 | Siena | Train Station | 06:55 | Milan | Lampugnano Bus Station | Premium Economy | £13 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 04/11/2026 01:05:00 to Lampugnano Bus Station, Milan (Italy) arriving at 04/11/2026 06:55:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 5h 50m
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| FlixBus | 6h 49m | 14:51 | Siena | Bus Stop | 21:40 | Milan | Lampugnano Bus Station | Economy | £40 |
A Bus from FlixBus goes from Bus Stop, Siena (Italy) at 04/11/2026 14:51:00 to Lampugnano Bus Station, Milan (Italy) arriving at 04/11/2026 21:40:00. 50 Economy ticket for £40 per person are available. Travel duration is 6h 49m
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| Itabus | 6h 30m | 01:05 | Siena | Train Station | 07:35 | Milan | San Donato Bus Station | Premium Economy | £44 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 04/11/2026 01:05:00 to San Donato Bus Station, Milan (Italy) arriving at 04/11/2026 07:35:00. 50 Premium Economy ticket for £44 per person are available. Travel duration is 6h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 4h 30m | 00:45 | Siena | Train Station | 05:15 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 05/11/2026 00:45:00 to San Donato Bus Station, Milan (Italy) arriving at 05/11/2026 05:15:00. 50 Economy ticket for £6 per person are available. Travel duration is 4h 30m
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| FlixBus | 5h 50m | 06:10 | Siena | Train Station | 12:00 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 05/11/2026 06:10:00 to San Donato Bus Station, Milan (Italy) arriving at 05/11/2026 12:00:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 50m
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| FlixBus | 5h 15m | 09:20 | Siena | Train Station | 14:35 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 05/11/2026 09:20:00 to San Donato Bus Station, Milan (Italy) arriving at 05/11/2026 14:35:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 15m
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| Itabus | 5h 45m | 10:55 | Siena | Train Station | 16:40 | Milan | Lampugnano Bus Station | Premium Economy | £7 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 05/11/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 05/11/2026 16:40:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 5h 45m
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| Itabus | 4h 55m | 13:55 | Siena | Train Station | 18:50 | Milan | San Donato Bus Station | Premium Economy | £8 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 05/11/2026 13:55:00 to San Donato Bus Station, Milan (Italy) arriving at 05/11/2026 18:50:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 4h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 5h 45m | 10:55 | Siena | Train Station | 16:40 | Milan | Lampugnano Bus Station | Premium Economy | £6 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 06/11/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 06/11/2026 16:40:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 5h 45m
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| FlixBus | 6h 49m | 14:51 | Siena | Bus Stop | 21:40 | Milan | Lampugnano Bus Station | Economy | £7 |
A Bus from FlixBus goes from Bus Stop, Siena (Italy) at 06/11/2026 14:51:00 to Lampugnano Bus Station, Milan (Italy) arriving at 06/11/2026 21:40:00. 50 Economy ticket for £7 per person are available. Travel duration is 6h 49m
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| Itabus | 4h 55m | 13:55 | Siena | Train Station | 18:50 | Milan | San Donato Bus Station | Premium Economy | £13 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 06/11/2026 13:55:00 to San Donato Bus Station, Milan (Italy) arriving at 06/11/2026 18:50:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 4h 55m
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| Itabus | 5h 50m | 01:05 | Siena | Train Station | 06:55 | Milan | Lampugnano Bus Station | Premium Economy | £13 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 06/11/2026 01:05:00 to Lampugnano Bus Station, Milan (Italy) arriving at 06/11/2026 06:55:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 5h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 5h 45m | 10:55 | Siena | Train Station | 16:40 | Milan | Lampugnano Bus Station | Premium Economy | £7 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 07/11/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 07/11/2026 16:40:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 5h 45m
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| FlixBus | 6h 49m | 14:51 | Siena | Bus Stop | 21:40 | Milan | Lampugnano Bus Station | Economy | £7 |
A Bus from FlixBus goes from Bus Stop, Siena (Italy) at 07/11/2026 14:51:00 to Lampugnano Bus Station, Milan (Italy) arriving at 07/11/2026 21:40:00. 50 Economy ticket for £7 per person are available. Travel duration is 6h 49m
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| Itabus | 5h 10m | 17:55 | Siena | Train Station | 23:05 | Milan | San Donato Bus Station | Premium Economy | £11 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 07/11/2026 17:55:00 to San Donato Bus Station, Milan (Italy) arriving at 07/11/2026 23:05:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 5h 10m
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| Itabus | 8h 15m | 13:55 | Siena | Train Station | 22:10 | Milan | Lampugnano Bus Station | Premium Economy | £16 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 07/11/2026 13:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 07/11/2026 22:10:00. 50 Premium Economy ticket for £16 per person are available. Travel duration is 8h 15m
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Best Price Offer: The price for the cheapest coach from Siena to Milan is £6 on 06/11/2026. Flexible travellers save on ticket prices.
Frequency of bus connections between Siena and Milan
Facts about coaches from Siena to Milan
Compare all providers like Itabus and FlixBus that travel 20 times every day by bus from Siena to Milan in one click! Book your bus ticket from Siena to Milan starting from £6!
| Cheapest Bus | £6 |
| Fastest Bus | 4h 30m |
| Earliest Coach | 09:20 |
| Latest Coach | 17:55 |
| Daily Bus Connections | 20 Ø |
| Distance | 293.3 km |
| Coach Companies | Itabus and FlixBus |
Cheapest coach connections from Siena to Milan
Every day, 20 buses from 2 coach companies leave Siena for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/11/2026 and for the following days.
The cheapest time to travel from Siena to Milan
How to save money travelling from Siena to Milan
Book the ticket from Siena to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Siena to Milan, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Siena to Milan are also emptier.All bus stations and stops in Siena and Milan
The map below shows you where to find all the bus stations in Siena and Milan.
Compare the bus with other modes of transport
Service and Comfort on the bus from Siena to Milan
FAQs about the Siena to Milan bus
How much does a Siena - Milan coach trip cost?
How much could I save by comparing buses from Siena to Milan?
How many connections are available for the Siena - Milan route on average every day?
How long does a bus to Milan from Siena take?
What time is the first bus from Siena to Milan?
What time is the last coach from Siena to Milan?
Which bus companies serve the Siena - Milan route?
Is there a direct bus between Siena and Milan?
What can I take with me on the bus to Milan from Siena?
What equipment is available for the Siena Milan bus route?
How does CheckMyBus find the best bus deals from Siena to Milan?
How does CheckMyBus technology work for trips from Siena to Milan?
Available seat classes which are offered on the bus route Siena to Milan
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
More bus routes to Siena and to Milan
- Bus Routes to Siena
- Coach from Avellino to Siena
- Bus Bologna to Siena
- Buses Lucca to Siena
- Coach to Siena from Naples
- Perugia to Siena coach
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- Bus Rome to Siena
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- Buses Salerno to Siena
- Turin to Siena coach
- Bus Routes to Milan
- Bibione to Milan bus
- Catania to Milan bus
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- Coach from Crotone to Milan
- Foggia to Milan coach
- Coaches Lamezia Terme to Milan
- Coach to Milan from Lausanne
- Lecce to Milan coach
- Bus Lourdes to Milan
- Coach from Palermo to Milan
- Coaches Pescara to Milan
- Bus Piacenza to Milan
- Bus Pinzolo to Milan
- Coach Rosarno to Milan
- Buses Saint-Vincent to Milan
- Sanremo to Milan bus
- Coach to Milan from Sibari
- Coach to Milan from Taranto
- Bus to Milan from Vibo Valentia
- Coach Vieste to Milan
