Compare all timetables for the bus from Siena to Milan
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 5h 50m | 06:10 | Siena | Train Station | 12:00 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 18/06/2026 06:10:00 to San Donato Bus Station, Milan (Italy) arriving at 18/06/2026 12:00:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 50m
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| FlixBus | 6h 50m | 06:10 | Siena | Train Station | 13:00 | Milan | Lampugnano Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 18/06/2026 06:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 18/06/2026 13:00:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 50m
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| FlixBus | 5h 55m | 07:50 | Siena | Train Station | 13:45 | Milan | Lampugnano Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 18/06/2026 07:50:00 to Lampugnano Bus Station, Milan (Italy) arriving at 18/06/2026 13:45:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 55m
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| Itabus | 4h 55m | 13:55 | Siena | Train Station | 18:50 | Milan | San Donato Bus Station | Premium Economy | £13 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 18/06/2026 13:55:00 to San Donato Bus Station, Milan (Italy) arriving at 18/06/2026 18:50:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 4h 55m
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| Itabus | 5h 45m | 10:55 | Siena | Train Station | 16:40 | Milan | Lampugnano Bus Station | Premium Economy | £13 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 18/06/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 18/06/2026 16:40:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 5h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 5h 50m | 06:10 | Siena | Train Station | 12:00 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 19/06/2026 06:10:00 to San Donato Bus Station, Milan (Italy) arriving at 19/06/2026 12:00:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 50m
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| FlixBus | 4h 50m | 06:40 | Siena | Train Station | 11:30 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 19/06/2026 06:40:00 to San Donato Bus Station, Milan (Italy) arriving at 19/06/2026 11:30:00. 50 Economy ticket for £6 per person are available. Travel duration is 4h 50m
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| FlixBus | 6h 50m | 06:10 | Siena | Train Station | 13:00 | Milan | Lampugnano Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 19/06/2026 06:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 19/06/2026 13:00:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 50m
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| Itabus | 5h 45m | 10:55 | Siena | Train Station | 16:40 | Milan | Lampugnano Bus Station | Premium Economy | £16 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 19/06/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 19/06/2026 16:40:00. 50 Premium Economy ticket for £16 per person are available. Travel duration is 5h 45m
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| Itabus | 4h 55m | 13:55 | Siena | Train Station | 18:50 | Milan | San Donato Bus Station | Premium Economy | £16 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 19/06/2026 13:55:00 to San Donato Bus Station, Milan (Italy) arriving at 19/06/2026 18:50:00. 50 Premium Economy ticket for £16 per person are available. Travel duration is 4h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 5h 50m | 06:10 | Siena | Train Station | 12:00 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 20/06/2026 06:10:00 to San Donato Bus Station, Milan (Italy) arriving at 20/06/2026 12:00:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 50m
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| FlixBus | 4h 50m | 06:40 | Siena | Train Station | 11:30 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 20/06/2026 06:40:00 to San Donato Bus Station, Milan (Italy) arriving at 20/06/2026 11:30:00. 50 Economy ticket for £6 per person are available. Travel duration is 4h 50m
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| FlixBus | 6h 50m | 06:10 | Siena | Train Station | 13:00 | Milan | Lampugnano Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 20/06/2026 06:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 20/06/2026 13:00:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 50m
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| Itabus | 5h 45m | 10:55 | Siena | Train Station | 16:40 | Milan | Lampugnano Bus Station | Premium Economy | £13 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 20/06/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 20/06/2026 16:40:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 5h 45m
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| Itabus | 4h 55m | 13:55 | Siena | Train Station | 18:50 | Milan | San Donato Bus Station | Premium Economy | £16 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 20/06/2026 13:55:00 to San Donato Bus Station, Milan (Italy) arriving at 20/06/2026 18:50:00. 50 Premium Economy ticket for £16 per person are available. Travel duration is 4h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 5h 50m | 06:10 | Siena | Train Station | 12:00 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 21/06/2026 06:10:00 to San Donato Bus Station, Milan (Italy) arriving at 21/06/2026 12:00:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 50m
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| FlixBus | 5h 15m | 09:20 | Siena | Train Station | 14:35 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 21/06/2026 09:20:00 to San Donato Bus Station, Milan (Italy) arriving at 21/06/2026 14:35:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 15m
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| FlixBus | 6h 50m | 06:10 | Siena | Train Station | 13:00 | Milan | Lampugnano Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 21/06/2026 06:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 21/06/2026 13:00:00. 50 Economy ticket for £6 per person are available. Travel duration is 6h 50m
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| Itabus | 5h 45m | 10:55 | Siena | Train Station | 16:40 | Milan | Lampugnano Bus Station | Premium Economy | £8 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 21/06/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 21/06/2026 16:40:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 5h 45m
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| Itabus | 5h 50m | 01:05 | Siena | Piazza Antonio Gramsci | 06:55 | Milan | Lampugnano Bus Station | Economy | £15 |
A Bus from Itabus goes from Piazza Antonio Gramsci, Siena (Italy) at 21/06/2026 01:05:00 to Lampugnano Bus Station, Milan (Italy) arriving at 21/06/2026 06:55:00. 50 Economy ticket for £15 per person are available. Travel duration is 5h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 5h 45m | 10:55 | Siena | Train Station | 16:40 | Milan | Lampugnano Bus Station | Premium Economy | £9 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 22/06/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 22/06/2026 16:40:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 5h 45m
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| Itabus | 4h 55m | 13:55 | Siena | Train Station | 18:50 | Milan | San Donato Bus Station | Premium Economy | £16 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 22/06/2026 13:55:00 to San Donato Bus Station, Milan (Italy) arriving at 22/06/2026 18:50:00. 50 Premium Economy ticket for £16 per person are available. Travel duration is 4h 55m
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| Itabus | 5h 50m | 01:05 | Siena | Train Station | 06:55 | Milan | Lampugnano Bus Station | Premium Economy | £22 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 22/06/2026 01:05:00 to Lampugnano Bus Station, Milan (Italy) arriving at 22/06/2026 06:55:00. 50 Premium Economy ticket for £22 per person are available. Travel duration is 5h 50m
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| Itabus | 6h 35m | 01:05 | Siena | Train Station | 07:40 | Milan | San Donato Bus Station | Premium Economy | £53 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 22/06/2026 01:05:00 to San Donato Bus Station, Milan (Italy) arriving at 22/06/2026 07:40:00. 50 Premium Economy ticket for £53 per person are available. Travel duration is 6h 35m
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| Itabus | 6h 0m | 01:05 | Siena | Train Station | 07:05 | Milan | San Donato Bus Station | Premium Economy | £57 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 22/06/2026 01:05:00 to San Donato Bus Station, Milan (Italy) arriving at 22/06/2026 07:05:00. 50 Premium Economy ticket for £57 per person are available. Travel duration is 6h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 4h 30m | 00:45 | Siena | Train Station | 05:15 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 23/06/2026 00:45:00 to San Donato Bus Station, Milan (Italy) arriving at 23/06/2026 05:15:00. 50 Economy ticket for £6 per person are available. Travel duration is 4h 30m
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| FlixBus | 5h 50m | 06:10 | Siena | Train Station | 12:00 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 23/06/2026 06:10:00 to San Donato Bus Station, Milan (Italy) arriving at 23/06/2026 12:00:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 50m
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| FlixBus | 5h 15m | 06:30 | Siena | Train Station | 11:45 | Milan | San Donato Bus Station | Economy | £6 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 23/06/2026 06:30:00 to San Donato Bus Station, Milan (Italy) arriving at 23/06/2026 11:45:00. 50 Economy ticket for £6 per person are available. Travel duration is 5h 15m
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| Itabus | 5h 45m | 10:55 | Siena | Train Station | 16:40 | Milan | Lampugnano Bus Station | Premium Economy | £9 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 23/06/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 23/06/2026 16:40:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 5h 45m
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| Itabus | 4h 55m | 13:55 | Siena | Train Station | 18:50 | Milan | San Donato Bus Station | Premium Economy | £9 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 23/06/2026 13:55:00 to San Donato Bus Station, Milan (Italy) arriving at 23/06/2026 18:50:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 4h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 5h 45m | 10:55 | Siena | Train Station | 16:40 | Milan | Lampugnano Bus Station | Premium Economy | £8 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 24/06/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 24/06/2026 16:40:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 5h 45m
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| FlixBus | 5h 50m | 06:10 | Siena | Train Station | 12:00 | Milan | San Donato Bus Station | Economy | £9 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 24/06/2026 06:10:00 to San Donato Bus Station, Milan (Italy) arriving at 24/06/2026 12:00:00. 50 Economy ticket for £9 per person are available. Travel duration is 5h 50m
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| FlixBus | 6h 50m | 06:10 | Siena | Train Station | 13:00 | Milan | Lampugnano Bus Station | Economy | £9 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 24/06/2026 06:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 24/06/2026 13:00:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 50m
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| FlixBus | 4h 30m | 00:45 | Siena | Train Station | 05:15 | Milan | San Donato Bus Station | Economy | £10 |
A Bus from FlixBus goes from Train Station, Siena (Italy) at 24/06/2026 00:45:00 to San Donato Bus Station, Milan (Italy) arriving at 24/06/2026 05:15:00. 50 Economy ticket for £10 per person are available. Travel duration is 4h 30m
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| Itabus | 4h 55m | 13:55 | Siena | Train Station | 18:50 | Milan | San Donato Bus Station | Premium Economy | £16 |
A Bus from Itabus goes from Train Station, Siena (Italy) at 24/06/2026 13:55:00 to San Donato Bus Station, Milan (Italy) arriving at 24/06/2026 18:50:00. 50 Premium Economy ticket for £16 per person are available. Travel duration is 4h 55m
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Best Price Offer: The price for the cheapest coach from Siena to Milan is £6 on 18/06/2026. Flexible travellers save on ticket prices.
Frequency of bus connections between Siena and Milan
Facts about coaches from Siena to Milan
Compare all providers like FlixBus and Itabus that travel 23 times every day by bus from Siena to Milan in one click! Book your bus ticket from Siena to Milan starting from £6!
| Cheapest Bus | £6 |
| Fastest Bus | 4h 30m |
| Earliest Coach | 00:45 |
| Latest Coach | 15:05 |
| Daily Bus Connections | 23 Ø |
| Distance | 293.3 km |
| Coach Companies | FlixBus and Itabus |
Cheapest coach connections from Siena to Milan
Every day, 23 buses from 2 coach companies leave Siena for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 18/06/2026 and for the following days.
The cheapest time to travel from Siena to Milan
How to save money travelling from Siena to Milan
Book the ticket from Siena to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Siena to Milan, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Siena to Milan are also emptier.All bus stations and stops in Siena and Milan
The map below shows you where to find all the bus stations in Siena and Milan.
Compare the bus with other modes of transport
Service and Comfort on the bus from Siena to Milan
FAQs about the Siena to Milan bus
How much does a Siena - Milan coach trip cost?
How much could I save by comparing buses from Siena to Milan?
How many connections are available for the Siena - Milan route on average every day?
How long does a bus to Milan from Siena take?
What time is the first bus from Siena to Milan?
What time is the last coach from Siena to Milan?
Which bus companies serve the Siena - Milan route?
Is there a direct bus between Siena and Milan?
What can I take with me on the bus to Milan from Siena?
What equipment is available for the Siena Milan bus route?
How does CheckMyBus find the best bus deals from Siena to Milan?
How does CheckMyBus technology work for trips from Siena to Milan?
Available seat classes which are offered on the bus route Siena to Milan
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
More bus routes to Siena and to Milan
- Bus Routes to Siena
- Arezzo to Siena coach
- Bus Bologna to Siena
- Bus from Cosenza to Siena
- Perugia to Siena coach
- Bus Pescara to Siena
- Prato to Siena bus
- Bus Rome to Siena
- Sala Consilina to Siena coach
- Buses Salerno to Siena
- Coach Taranto to Siena
- Turin to Siena coach
- Bus Routes to Milan
- Bus Antibes to Milan
- Coaches Avignon to Milan
- Coach from Catanzaro to Milan
- Coach Ciro Marina to Milan
- Loano to Milan coach
- Messina to Milan bus
- Buses Perugia to Milan
- Bus to Milan from Peschici
- Bus Piacenza to Milan
- Pré-Saint-Didier to Milan bus
- Coach Rimini to Milan
- Coach Rosarno to Milan
- Sala Consilina to Milan bus
- Coaches Salerno to Milan
- Sanremo to Milan bus
- Savona to Milan coach
- Coach to Milan from Taranto
- Bus to Milan from Vibo Valentia
- Vicenza to Milan bus
- Coaches Villa San Giovanni to Milan
