Bus tickets Palermo to Milan from £46

Compare all the coach companies and find the best price with CheckMyBus
1
Search accommodation with Booking.com
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Palermo to Milan

Here is a selection of the cheapest bus trips from the schedule from Palermo to Milan from various bus operators like FlixBus, Autoservizi Salemi or Sais Trasporti for the next days.

today
from £68
tomorrow
from £84
Sunday
from £66
Monday
from £46
Tuesday
from £46
Wednesday
from £55
Thursday
from £48

Cheapest bus trips today

Prices are for one way and one person
  • Autoservizi Salemi
    19h 10m
    0
    18:00
    Palermo
    Via Tommaso Fazello Bus Stop
    13:10
    Milan
    San Donato Bus Station
    0
    Autoservizi Salemi
    Economy
    £68
  • Autoservizi Salemi
    19h 50m
    0
    18:00
    Palermo
    Via Tommaso Fazello Bus Stop
    13:50
    Milan
    Lampugnano Bus Station
    0
    Autoservizi Salemi
    Economy
    £68
  • FlixBus
    23h 45m
    0
    09:10
    Palermo
    Via Tommaso Fazello Bus Stop
    08:55
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    £70
  • FlixBus
    24h 20m
    0
    09:10
    Palermo
    Via Tommaso Fazello Bus Stop
    09:30
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    £70
  • Sais Trasporti
    24h 10m
    0
    18:00
    Palermo
    Via Tommaso Fazello Bus Stop
    18:10
    Milan
    San Donato Bus Station
    0
    Sais Trasporti
    Economy
    £72

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    23h 45m
    0
    09:10
    Palermo
    Via Tommaso Fazello Bus Stop
    08:55
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    £84
  • FlixBus
    22h 15m
    0
    15:25
    Palermo
    Via Tommaso Fazello Bus Stop
    13:40
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    £84
  • FlixBus
    24h 20m
    0
    09:10
    Palermo
    Via Tommaso Fazello Bus Stop
    09:30
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    £85
  • FlixBus
    23h 10m
    0
    15:25
    Palermo
    Via Tommaso Fazello Bus Stop
    14:35
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    £89
  • FlixBus
    24h 45m
    0
    11:10
    Palermo
    Via Tommaso Fazello Bus Stop
    11:55
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    £90

Cheapest bus trips Sunday

Prices are for one way and one person
  • FlixBus
    22h 15m
    0
    15:25
    Palermo
    Via Tommaso Fazello Bus Stop
    13:40
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    £66
  • Autoservizi Salemi
    19h 50m
    0
    18:00
    Palermo
    Via Tommaso Fazello Bus Stop
    13:50
    Milan
    Lampugnano Bus Station
    0
    Autoservizi Salemi
    Economy
    £68
  • Autoservizi Salemi
    19h 10m
    0
    18:00
    Palermo
    Via Tommaso Fazello Bus Stop
    13:10
    Milan
    San Donato Bus Station
    0
    Autoservizi Salemi
    Economy
    £68
  • Sais Trasporti
    24h 55m
    0
    18:00
    Palermo
    Via Tommaso Fazello Bus Stop
    18:55
    Milan
    Lampugnano Bus Station
    0
    Sais Trasporti
    Economy
    £74
  • Sais Trasporti
    24h 10m
    0
    18:00
    Palermo
    Via Tommaso Fazello Bus Stop
    18:10
    Milan
    San Donato Bus Station
    0
    Sais Trasporti
    Economy
    £74

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    22h 15m
    0
    15:25
    Palermo
    Via Tommaso Fazello Bus Stop
    13:40
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    £46
  • Autoservizi Salemi
    19h 10m
    0
    18:00
    Palermo
    Via Tommaso Fazello Bus Stop
    13:10
    Milan
    San Donato Bus Station
    0
    Autoservizi Salemi
    Economy
    £68
  • Autoservizi Salemi
    19h 50m
    0
    18:00
    Palermo
    Via Tommaso Fazello Bus Stop
    13:50
    Milan
    Lampugnano Bus Station
    0
    Autoservizi Salemi
    Economy
    £68
  • FlixBus
    23h 10m
    0
    15:25
    Palermo
    Via Tommaso Fazello Bus Stop
    14:35
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    £74
  • FlixBus
    24h 45m
    0
    11:10
    Palermo
    Via Tommaso Fazello Bus Stop
    11:55
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    £87

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    22h 15m
    0
    15:25
    Palermo
    Via Tommaso Fazello Bus Stop
    13:40
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    £46
  • FlixBus
    24h 45m
    0
    11:10
    Palermo
    Via Tommaso Fazello Bus Stop
    11:55
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    £89
  • FlixBus
    24h 15m
    0
    18:15
    Palermo
    Via Tommaso Fazello Bus Stop
    18:30
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    £104
  • FlixBus
    23h 45m
    0
    09:10
    Palermo
    Via Tommaso Fazello Bus Stop
    08:55
    Milan
    San Donato Bus Station
    0
    FlixBus
    Economy
    £105
  • FlixBus
    24h 20m
    0
    09:10
    Palermo
    Via Tommaso Fazello Bus Stop
    09:30
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    £105

Cheapest bus trips Wednesday

Prices are for one way and one person
  • FlixBus
    22h 15m
    0
    15:25
    Palermo
    Via Tommaso Fazello Bus Stop
    13:40
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    £55
  • FlixBus
    24h 45m
    0
    11:10
    Palermo
    Via Tommaso Fazello Bus Stop
    11:55
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    £73
  • Autoservizi Salemi
    19h 50m
    0
    18:00
    Palermo
    Via Tommaso Fazello Bus Stop
    13:50
    Milan
    Lampugnano Bus Station
    0
    Autoservizi Salemi
    Economy
    £75
  • Autoservizi Salemi
    19h 10m
    0
    18:00
    Palermo
    Via Tommaso Fazello Bus Stop
    13:10
    Milan
    San Donato Bus Station
    0
    Autoservizi Salemi
    Economy
    £75
  • Sais Trasporti
    24h 55m
    0
    18:00
    Palermo
    Via Tommaso Fazello Bus Stop
    18:55
    Milan
    Lampugnano Bus Station
    0
    Sais Trasporti
    Economy
    £77

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    22h 15m
    0
    15:25
    Palermo
    Via Tommaso Fazello Bus Stop
    13:40
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    £48
  • Autoservizi Salemi
    19h 10m
    0
    18:00
    Palermo
    Via Tommaso Fazello Bus Stop
    13:10
    Milan
    San Donato Bus Station
    0
    Autoservizi Salemi
    Economy
    £75
  • Autoservizi Salemi
    19h 50m
    0
    18:00
    Palermo
    Via Tommaso Fazello Bus Stop
    13:50
    Milan
    Lampugnano Bus Station
    0
    Autoservizi Salemi
    Economy
    £75
  • FlixBus
    24h 5m
    0
    17:10
    Palermo
    Via Tommaso Fazello Bus Stop
    17:15
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    £78
  • FlixBus
    24h 45m
    0
    11:10
    Palermo
    Via Tommaso Fazello Bus Stop
    11:55
    Milan
    Lampugnano Bus Station
    0
    FlixBus
    Economy
    £79

Frequency of bus connections between Palermo and Milan

See here how frequent the connections between Palermo and Milan are, during different times and days of the week.
Sunday is the busiest day, with more than 13 daily coaches from Palermo to Milan. Tuesday has instead the fewest connections, with only 6 daily coaches between Palermo and Milan.
The busiest time of the day is the Evening, with 30 coaches from Palermo to Milan, while Afternoon sees the fewest connections between Palermo and Milan, with 16 offers.

Facts about coaches from Palermo to Milan

Compare all providers like FlixBus, Autoservizi Salemi and Sais Trasporti that travel 9 times every day by bus from Palermo to Milan in one click! Book your bus ticket from Palermo to Milan starting from £46!

Cheapest Bus £46
Fastest Bus 19h 10m
Earliest Coach 09:10
Latest Coach 18:15
Daily Bus Connections 9 Ø
Distance 887.2 km
Coach Companies FlixBus, Autoservizi Salemi and Sais Trasporti

Cheapest coach connections from Palermo to Milan

Every day, 9 buses from 3 coach companies leave Palermo for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 27/06/2025 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 23/06
Tuesday 24/06
Wednesday 25/06
Thursday 26/06
Friday 27/06
£70
Saturday 28/06
£84
Sunday 29/06
£66
Monday 30/06
£46
Tuesday 01/07
£46
Wednesday 02/07
£55
Thursday 03/07
£48
Friday 04/07
£59
Saturday 05/07
£75
Sunday 06/07
£57
Monday 07/07
£49
Tuesday 08/07
£48
Wednesday 09/07
£46
Thursday 10/07
£54
Friday 11/07
£66
Saturday 12/07
£57
Sunday 13/07
£62
Monday 14/07
£75
Tuesday 15/07
£71
Wednesday 16/07
£64
Thursday 17/07
£77
Friday 18/07
£68
Saturday 19/07
£77
Sunday 20/07

The cheapest time to travel from Palermo to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Palermo to Milan, for the next 30 days.
With a price starting from £46, Monday is the cheapest day for a coach from Palermo to Milan. Saturday instead is the most expensive day with prices starting from £84.
Afternoon is the cheapest day time for bus tickets from Palermo to Milan, with £46. Morning is the most expensive time of the day with prices starting from £70.

How to save money travelling from Palermo to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Palermo to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Palermo to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Palermo to Milan are also emptier.

Beloved bus companies from Palermo to Milan

These are the most booked bus companies between Palermo to Milan from our users.

FlixBus from Palermo to Milan

FlixBus

Here you will find the key facts about the FlixBus bus route Palermo to Milan:

Cheapest Price £46
Fastest Coach 22h 15m
Earliest Coach 09:10
Last Coach 18:15
Daily Connections 6 Ø
Found on 26/06/2025

All bus stations and stops in Palermo and Milan

The map below shows you where to find all the bus stations in Palermo and Milan.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Palermo to Milan? Compare all modes of transports from Palermo to Milan.

Service and Comfort on the bus from Palermo to Milan

Want to know which seat classes are available on the coaches from Palermo to Milan? Or which bus companies serve the route Palermo to Milan? Below you will find answers to your questions.

FAQs about the Palermo to Milan bus

How much does a Palermo - Milan coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Palermo - Milan bus trip is available from £46 and takes 22h 15m. Compare offers and save money!

How much could I save by comparing buses from Palermo to Milan?

The connection Palermo to Milan is offered by 3 companies with ticket prices ranging from £46 to £129. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Palermo - Milan route on average every day?

Each day, the bus route from Palermo to Milan is offered by roughly 9 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Milan from Palermo take?

The quickest coach from Palermo to Milan is provided by Autoservizi Salemi and takes 19h 10m. Coach tickets for this connection cost £68. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Palermo to Milan?

The earliest bus to Milan departs from Palermo at 09:10. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Palermo to Milan?

The latest bus to Milan departs from Palermo at 18:15. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Palermo - Milan route?

Passengers looking to travel from Palermo to Milan can travel with FlixBus, Autoservizi Salemi and Sais Trasporti. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Palermo and Milan?

You can check all the direct connections between Palermo and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Autoservizi Salemi and Sais Trasporti.

What can I take with me on the bus to Milan from Palermo?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Palermo Milan bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Palermo Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Palermo to Milan on your planned travel date.

Available seat classes which are offered on the bus route Palermo to Milan

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Palermo and to Milan

Here’s an overview of the most popular bus routes to Palermo and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!
Modica to Palermo coach Modica to Palermo coach
Coach to Palermo from Comiso Coach to Palermo from Comiso
Bus to Palermo from Bari Bus to Palermo from Bari
Enna to Palermo bus Enna to Palermo bus
Villa San Giovanni to Milan coach Villa San Giovanni to Milan coach
Coaches Lauria to Milan Coaches Lauria to Milan
Bus to Milan from Padua Bus to Milan from Padua
Coach from Zurich to Milan Coach from Zurich to Milan
Popular Airport Transfers to Palermo and to Milan
CheckMyBus › Coaches in Italy › Coach to Palermo › Coach to Milan

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To show you the best bus deals, we and our partners use technical, analytical, and marketing cookies for ads personalisation. We remember your anonymized details to provide a personalized experience.