Bus tickets Palermo to Milan from £46

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Compare all timetables for the bus from Palermo to Milan

Here is a selection of the cheapest bus trips from the schedule from Palermo to Milan from various bus operators like FlixBus or Autoservizi Salemi for the next days.

today
£90
tomorrow
£79
Thursday
£61
Friday
£76
Saturday
£82
Sunday
£75
Monday
£59

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 20m 15:25 Palermo Via Tommaso Fazello Bus Stop 13:45 Milan Lampugnano Bus Station  Economy £90
FlixBus 24h 30m 21:10 Palermo Via Tommaso Fazello Bus Stop 21:40 Milan Lampugnano Bus Station  Economy £92
FlixBus 24h 45m 21:10 Palermo Via Tommaso Fazello Bus Stop 21:55 Milan San Donato Bus Station  Economy £93
FlixBus 23h 10m 15:25 Palermo Via Tommaso Fazello Bus Stop 14:35 Milan San Donato Bus Station  Economy £98

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 30m 21:10 Palermo Via Tommaso Fazello Bus Stop 21:40 Milan Lampugnano Bus Station  Economy £79
FlixBus 23h 45m 21:10 Palermo Via Tommaso Fazello Bus Stop 20:55 Milan San Donato Bus Station  Economy £81
FlixBus 23h 10m 15:25 Palermo Via Tommaso Fazello Bus Stop 14:35 Milan San Donato Bus Station  Economy £95
FlixBus 22h 20m 15:25 Palermo Via Tommaso Fazello Bus Stop 13:45 Milan Lampugnano Bus Station  Economy £96
  • Did you know that if you travel from Palermo to Milan via Siena, you can save more than £34? You can find the corresponding connections below.
    • FlixBus
      22h 20m
      0
      15:25
      Palermo
      Via Tommaso Fazello Bus Stop
      07:45
      Siena
      Train Station
      0
      FlixBus
      Economy
      £39
      • Waiting Time 0h 5m
    • FlixBus
      5h 55m
      0
      07:50
      Siena
      Train Station
      13:45
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      £6
    Travel time is the same as the direct connection, but you will save £34

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 10m 15:25 Palermo Via Tommaso Fazello Bus Stop 14:35 Milan San Donato Bus Station  Economy £61
FlixBus 22h 20m 15:25 Palermo Via Tommaso Fazello Bus Stop 13:45 Milan Lampugnano Bus Station  Economy £73
FlixBus 25h 30m 21:10 Palermo Via Tommaso Fazello Bus Stop 22:40 Milan Lampugnano Bus Station  Economy £73
FlixBus 23h 45m 21:10 Palermo Via Tommaso Fazello Bus Stop 20:55 Milan San Donato Bus Station  Economy £80
  • Did you know that if you travel from Palermo to Milan via Siena, you can save more than £16? You can find the corresponding connections below.
    • FlixBus
      22h 20m
      0
      15:25
      Palermo
      Via Tommaso Fazello Bus Stop
      07:45
      Siena
      Train Station
      0
      FlixBus
      Economy
      £39
      • Waiting Time 0h 5m
    • FlixBus
      5h 55m
      0
      07:50
      Siena
      Train Station
      13:45
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      £6
    Travel time is the same as the direct connection, but you will save £16

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 30m 21:10 Palermo Via Tommaso Fazello Bus Stop 21:40 Milan Lampugnano Bus Station  Economy £76
FlixBus 23h 10m 15:25 Palermo Via Tommaso Fazello Bus Stop 14:35 Milan San Donato Bus Station  Economy £80
FlixBus 23h 45m 21:10 Palermo Via Tommaso Fazello Bus Stop 20:55 Milan San Donato Bus Station  Economy £82
FlixBus 22h 20m 15:25 Palermo Via Tommaso Fazello Bus Stop 13:45 Milan Lampugnano Bus Station  Economy £93
  • Did you know that if you travel from Palermo to Milan via Siena, you can save more than £31? You can find the corresponding connections below.
    • FlixBus
      22h 20m
      0
      15:25
      Palermo
      Via Tommaso Fazello Bus Stop
      07:45
      Siena
      Train Station
      0
      FlixBus
      Economy
      £39
      • Waiting Time 0h 5m
    • FlixBus
      5h 55m
      0
      07:50
      Siena
      Train Station
      13:45
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      £6
    Travel time is the same as the direct connection, but you will save £31

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 10m 15:25 Palermo Via Tommaso Fazello Bus Stop 14:35 Milan San Donato Bus Station  Economy £82
FlixBus 22h 20m 15:25 Palermo Via Tommaso Fazello Bus Stop 13:45 Milan Lampugnano Bus Station  Economy £82
FlixBus 24h 30m 21:10 Palermo Via Tommaso Fazello Bus Stop 21:40 Milan Lampugnano Bus Station  Economy £85
FlixBus 23h 45m 21:10 Palermo Via Tommaso Fazello Bus Stop 20:55 Milan San Donato Bus Station  Economy £95
  • Did you know that if you travel from Palermo to Milan via Siena, you can save more than £37? You can find the corresponding connections below.
    • FlixBus
      22h 20m
      0
      15:25
      Palermo
      Via Tommaso Fazello Bus Stop
      07:45
      Siena
      Train Station
      0
      FlixBus
      Economy
      £39
      • Waiting Time 0h 5m
    • FlixBus
      5h 55m
      0
      07:50
      Siena
      Train Station
      13:45
      Milan
      Lampugnano Bus Station
      0
      FlixBus
      Economy
      £6
    Travel time is the same as the direct connection, but you will save £37

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 20m 15:25 Palermo Via Tommaso Fazello Bus Stop 13:45 Milan Lampugnano Bus Station  Economy £75
FlixBus 23h 10m 15:25 Palermo Via Tommaso Fazello Bus Stop 14:35 Milan San Donato Bus Station  Economy £76
FlixBus 23h 45m 21:10 Palermo Via Tommaso Fazello Bus Stop 20:55 Milan San Donato Bus Station  Economy £94
FlixBus 24h 30m 21:10 Palermo Via Tommaso Fazello Bus Stop 21:40 Milan Lampugnano Bus Station  Economy £97
  • Did you know that if you travel from Palermo to Milan via Siena, you can save more than £33? You can find the corresponding connections below.
    • FlixBus
      23h 10m
      0
      15:25
      Palermo
      Via Tommaso Fazello Bus Stop
      07:45
      Siena
      Train Station
      0
      FlixBus
      Economy
      £35
      • Waiting Time 1h 35m
    • FlixBus
      5h 15m
      0
      09:20
      Siena
      Train Station
      14:35
      Milan
      San Donato Bus Station
      0
      FlixBus
      Economy
      £6
    Travel time is 0h 50m longer, but you will save £33

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 25h 10m 21:10 Palermo Via Tommaso Fazello Bus Stop 22:20 Milan San Donato Bus Station  Economy £59
FlixBus 24h 30m 21:10 Palermo Via Tommaso Fazello Bus Stop 21:40 Milan Lampugnano Bus Station  Economy £63
FlixBus 23h 10m 15:25 Palermo Via Tommaso Fazello Bus Stop 14:35 Milan San Donato Bus Station  Economy £69
Autoservizi Salemi 19h 10m 18:00 Palermo Via Tommaso Fazello Bus Stop 13:10 Milan San Donato Bus Station  Basic £71
Autoservizi Salemi 19h 50m 18:00 Palermo Via Tommaso Fazello Bus Stop 13:50 Milan Lampugnano Bus Station  Basic £71
  • Did you know that if you travel from Palermo to Milan via Siena, you can save more than £17? You can find the corresponding connections below.
    • FlixBus
      23h 10m
      0
      15:25
      Palermo
      Via Tommaso Fazello Bus Stop
      07:45
      Siena
      Train Station
      0
      FlixBus
      Economy
      £35
      • Waiting Time 1h 35m
    • FlixBus
      5h 15m
      0
      09:20
      Siena
      Train Station
      14:35
      Milan
      San Donato Bus Station
      0
      FlixBus
      Economy
      £6
    Travel time is 4h 0m longer, but you will save £17

Best Price Offer: The price for the cheapest coach from Palermo to Milan is £46 on 27/05/2026. Flexible travellers save on ticket prices.


Frequency of bus connections between Palermo and Milan

See here how frequent the connections between Palermo and Milan are, during different times and days of the week.
Monday is the busiest day, with more than 6 daily coaches from Palermo to Milan. Tuesday has instead the fewest connections, with only 4 daily coaches between Palermo and Milan.
The busiest time of the day is the Evening, with 16 coaches from Palermo to Milan, while Afternoon sees the fewest connections between Palermo and Milan, with 14 offers.

Facts about coaches from Palermo to Milan

Compare all providers like FlixBus and Autoservizi Salemi that travel 4 times every day by bus from Palermo to Milan in one click! Book your bus ticket from Palermo to Milan starting from £46!

Cheapest Bus £46
Fastest Bus 19h 10m
Earliest Coach 15:25
Latest Coach 21:10
Daily Bus Connections 4 Ø
Distance 887.2 km
Coach Companies FlixBus and Autoservizi Salemi

Cheapest coach connections from Palermo to Milan

Every day, 4 buses from 2 coach companies leave Palermo for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/05/2026 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 04/05
Tuesday 05/05
£90
Wednesday 06/05
£79
Thursday 07/05
£61
Friday 08/05
£76
Saturday 09/05
£82
Sunday 10/05
£75
Monday 11/05
£59
Tuesday 12/05
£60
Wednesday 13/05
£47
Thursday 14/05
£51
Friday 15/05
£58
Saturday 16/05
£60
Sunday 17/05
£63
Monday 18/05
£50
Tuesday 19/05
£51
Wednesday 20/05
£51
Thursday 21/05
£66
Friday 22/05
£61
Saturday 23/05
£59
Sunday 24/05
£63
Monday 25/05
£68
Tuesday 26/05
£55
Wednesday 27/05
£46
Thursday 28/05
£54
Friday 29/05
£58
Saturday 30/05
£66
Sunday 31/05

The cheapest time to travel from Palermo to Milan

See here on which day and which time of the day you can find the cheapest bus ticket from Palermo to Milan, for the next 30 days.
With a price starting from £46, Wednesday is the cheapest day for a coach from Palermo to Milan. Sunday instead is the most expensive day with prices starting from £63.
Evening is the cheapest day time for bus tickets from Palermo to Milan, with £59. Afternoon is the most expensive time of the day with prices starting from £61.

How to save money travelling from Palermo to Milan

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Palermo to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Palermo to Milan, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Palermo to Milan are also emptier.

All bus stations and stops in Palermo and Milan

The map below shows you where to find all the bus stations in Palermo and Milan.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Palermo to Milan? Compare all modes of transports from Palermo to Milan.

Service and Comfort on the bus from Palermo to Milan

Want to know which seat classes are available on the coaches from Palermo to Milan? Or which bus companies serve the route Palermo to Milan? Below you will find answers to your questions.

FAQs about the Palermo to Milan bus

How much does a Palermo - Milan coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Palermo - Milan bus trip is available from £46 and takes 25h 10m. Compare offers and save money!

How much could I save by comparing buses from Palermo to Milan?

The connection Palermo to Milan is offered by 2 companies with ticket prices ranging from £46 to £98. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Palermo - Milan route on average every day?

Each day, the bus route from Palermo to Milan is offered by roughly 4 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Milan from Palermo take?

The quickest coach from Palermo to Milan is provided by Autoservizi Salemi and takes 19h 10m. Coach tickets for this connection cost £71. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Palermo to Milan?

The earliest bus to Milan departs from Palermo at 15:25. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Palermo to Milan?

The latest bus to Milan departs from Palermo at 21:10. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Palermo - Milan route?

Passengers looking to travel from Palermo to Milan can travel with FlixBus and Autoservizi Salemi. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Palermo and Milan?

You can check all the direct connections between Palermo and Milan by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Autoservizi Salemi.

What can I take with me on the bus to Milan from Palermo?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Palermo Milan bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Palermo Milan bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Palermo to Milan on your planned travel date.

How does CheckMyBus find the best bus deals from Palermo to Milan?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Palermo and Milan. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Palermo to Milan?

Prices and availability for 4 trips between Palermo and Milan change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Palermo to Milan

Basic
Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Palermo and to Milan

Here’s an overview of the most popular bus routes to Palermo and to Milan. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus to Palermo from Villa San Giovanni Bus to Palermo from Villa San Giovanni
Coach from Caltanissetta to Palermo Coach from Caltanissetta to Palermo
Bus from Marsala to Palermo Bus from Marsala to Palermo
Bus Turin to Palermo Bus Turin to Palermo
Bus from Massa to Milan Bus from Massa to Milan
Caserta to Milan bus Caserta to Milan bus
Coach from Lausanne to Milan Coach from Lausanne to Milan
Bus from Piacenza to Milan Bus from Piacenza to Milan
Popular Airport Transfers to Palermo and to Milan
CheckMyBus › Coaches in Italy › Coach to Palermo › Coach to Milan

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