Compare all timetables for the bus from Palermo to Milan
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 10m | 15:25 | Palermo | Via Tommaso Fazello Bus Stop | 14:35 | Milan | San Donato Bus Station | Economy | £77 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 22/03/2026 15:25:00 to San Donato Bus Station, Milan (Italy) arriving at 23/03/2026 14:35:00. 50 Economy ticket for £77 per person are available. Travel duration is 23h 10m
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| FlixBus | 24h 45m | 17:10 | Palermo | Via Tommaso Fazello Bus Stop | 17:55 | Milan | Lampugnano Bus Station | Economy | £81 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 22/03/2026 17:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 23/03/2026 17:55:00. 50 Economy ticket for £81 per person are available. Travel duration is 24h 45m
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| FlixBus | 22h 20m | 15:25 | Palermo | Via Tommaso Fazello Bus Stop | 13:45 | Milan | Lampugnano Bus Station | Economy | £85 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 22/03/2026 15:25:00 to Lampugnano Bus Station, Milan (Italy) arriving at 23/03/2026 13:45:00. 50 Economy ticket for £85 per person are available. Travel duration is 22h 20m
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| FlixBus | 25h 20m | 17:10 | Palermo | Via Tommaso Fazello Bus Stop | 18:30 | Milan | San Donato Bus Station | Economy | £110 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 22/03/2026 17:10:00 to San Donato Bus Station, Milan (Italy) arriving at 23/03/2026 18:30:00. 50 Economy ticket for £110 per person are available. Travel duration is 25h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 24h 0m | 17:10 | Palermo | Via Tommaso Fazello Bus Stop | 17:10 | Milan | Lampugnano Bus Station | Economy | £107 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 23/03/2026 17:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 24/03/2026 17:10:00. 50 Economy ticket for £107 per person are available. Travel duration is 24h 0m
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| FlixBus | 25h 20m | 17:10 | Palermo | Via Tommaso Fazello Bus Stop | 18:30 | Milan | San Donato Bus Station | Economy | £113 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 23/03/2026 17:10:00 to San Donato Bus Station, Milan (Italy) arriving at 24/03/2026 18:30:00. 50 Economy ticket for £113 per person are available. Travel duration is 25h 20m
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| FlixBus | 23h 10m | 15:25 | Palermo | Via Tommaso Fazello Bus Stop | 14:35 | Milan | San Donato Bus Station | Economy | £119 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 23/03/2026 15:25:00 to San Donato Bus Station, Milan (Italy) arriving at 24/03/2026 14:35:00. 50 Economy ticket for £119 per person are available. Travel duration is 23h 10m
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| FlixBus | 22h 20m | 15:25 | Palermo | Via Tommaso Fazello Bus Stop | 13:45 | Milan | Lampugnano Bus Station | Economy | £127 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 23/03/2026 15:25:00 to Lampugnano Bus Station, Milan (Italy) arriving at 24/03/2026 13:45:00. 50 Economy ticket for £127 per person are available. Travel duration is 22h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 10m | 15:25 | Palermo | Via Tommaso Fazello Bus Stop | 14:35 | Milan | San Donato Bus Station | Economy | £32 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 25/03/2026 15:25:00 to San Donato Bus Station, Milan (Italy) arriving at 26/03/2026 14:35:00. 50 Economy ticket for £32 per person are available. Travel duration is 23h 10m
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| FlixBus | 22h 20m | 15:25 | Palermo | Via Tommaso Fazello Bus Stop | 13:45 | Milan | Lampugnano Bus Station | Economy | £56 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 25/03/2026 15:25:00 to Lampugnano Bus Station, Milan (Italy) arriving at 26/03/2026 13:45:00. 50 Economy ticket for £56 per person are available. Travel duration is 22h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 10m | 15:25 | Palermo | Via Tommaso Fazello Bus Stop | 14:35 | Milan | San Donato Bus Station | Economy | £58 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 26/03/2026 15:25:00 to San Donato Bus Station, Milan (Italy) arriving at 27/03/2026 14:35:00. 50 Economy ticket for £58 per person are available. Travel duration is 23h 10m
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| FlixBus | 24h 0m | 17:10 | Palermo | Via Tommaso Fazello Bus Stop | 17:10 | Milan | Lampugnano Bus Station | Economy | £63 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 26/03/2026 17:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 27/03/2026 17:10:00. 50 Economy ticket for £63 per person are available. Travel duration is 24h 0m
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| FlixBus | 25h 20m | 17:10 | Palermo | Via Tommaso Fazello Bus Stop | 18:30 | Milan | San Donato Bus Station | Economy | £65 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 26/03/2026 17:10:00 to San Donato Bus Station, Milan (Italy) arriving at 27/03/2026 18:30:00. 50 Economy ticket for £65 per person are available. Travel duration is 25h 20m
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| FlixBus | 22h 20m | 15:25 | Palermo | Via Tommaso Fazello Bus Stop | 13:45 | Milan | Lampugnano Bus Station | Economy | £70 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 26/03/2026 15:25:00 to Lampugnano Bus Station, Milan (Italy) arriving at 27/03/2026 13:45:00. 50 Economy ticket for £70 per person are available. Travel duration is 22h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 10m | 15:25 | Palermo | Via Tommaso Fazello Bus Stop | 14:35 | Milan | San Donato Bus Station | Economy | £69 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 27/03/2026 15:25:00 to San Donato Bus Station, Milan (Italy) arriving at 28/03/2026 14:35:00. 50 Economy ticket for £69 per person are available. Travel duration is 23h 10m
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| FlixBus | 22h 20m | 15:25 | Palermo | Via Tommaso Fazello Bus Stop | 13:45 | Milan | Lampugnano Bus Station | Economy | £71 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 27/03/2026 15:25:00 to Lampugnano Bus Station, Milan (Italy) arriving at 28/03/2026 13:45:00. 50 Economy ticket for £71 per person are available. Travel duration is 22h 20m
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| FlixBus | 25h 20m | 17:10 | Palermo | Via Tommaso Fazello Bus Stop | 18:30 | Milan | San Donato Bus Station | Economy | £72 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 27/03/2026 17:10:00 to San Donato Bus Station, Milan (Italy) arriving at 28/03/2026 18:30:00. 50 Economy ticket for £72 per person are available. Travel duration is 25h 20m
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| FlixBus | 24h 0m | 17:10 | Palermo | Via Tommaso Fazello Bus Stop | 17:10 | Milan | Lampugnano Bus Station | Economy | £72 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 27/03/2026 17:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 28/03/2026 17:10:00. 50 Economy ticket for £72 per person are available. Travel duration is 24h 0m
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FlixBus30h 39m017:10PalermoVia Tommaso Fazello Bus Stop11:25SienaTrain Station0EconomyA Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 27/03/2026 17:10:00 to Train Station, Siena (Italy) arriving at 28/03/2026 11:25:00. 50 Economy ticket for £40 per person are available. Travel duration is 18h 15m
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Itabus5h 14m018:35SienaTrain Station23:49MilanSan Donato Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 28/03/2026 18:35:00 to San Donato Bus Station, Milan (Italy) arriving at 28/03/2026 23:49:00. 50 Premium Economy ticket for £19 per person are available. Travel duration is 5h 14m
Waiting Time 7h 10m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 45m | 17:10 | Palermo | Via Tommaso Fazello Bus Stop | 17:55 | Milan | Lampugnano Bus Station | Economy | £61 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 28/03/2026 17:10:00 to Lampugnano Bus Station, Milan (Italy) arriving at 29/03/2026 17:55:00. 50 Economy ticket for £61 per person are available. Travel duration is 23h 45m
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| FlixBus | 24h 20m | 17:10 | Palermo | Via Tommaso Fazello Bus Stop | 18:30 | Milan | San Donato Bus Station | Economy | £61 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 28/03/2026 17:10:00 to San Donato Bus Station, Milan (Italy) arriving at 29/03/2026 18:30:00. 50 Economy ticket for £61 per person are available. Travel duration is 24h 20m
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| FlixBus | 22h 20m | 15:25 | Palermo | Via Tommaso Fazello Bus Stop | 14:45 | Milan | Lampugnano Bus Station | Economy | £67 |
A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 28/03/2026 15:25:00 to Lampugnano Bus Station, Milan (Italy) arriving at 29/03/2026 14:45:00. 50 Economy ticket for £67 per person are available. Travel duration is 22h 20m
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| Autoservizi Salemi | 19h 50m | 18:00 | Palermo | Via Tommaso Fazello Bus Stop | 14:50 | Milan | Lampugnano Bus Station | Basic | £69 |
A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 28/03/2026 18:00:00 to Lampugnano Bus Station, Milan (Italy) arriving at 29/03/2026 14:50:00. 50 Basic ticket for £69 per person are available. Travel duration is 19h 50m
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| Autoservizi Salemi | 19h 10m | 18:00 | Palermo | Via Tommaso Fazello Bus Stop | 14:10 | Milan | San Donato Bus Station | Basic | £69 |
A Bus from Autoservizi Salemi goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 28/03/2026 18:00:00 to San Donato Bus Station, Milan (Italy) arriving at 29/03/2026 14:10:00. 50 Basic ticket for £69 per person are available. Travel duration is 19h 10m
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FlixBus25h 15m015:25PalermoVia Tommaso Fazello Bus Stop07:45SienaTrain Station0EconomyA Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 29/03/2026 15:25:00 to Train Station, Siena (Italy) arriving at 30/03/2026 07:45:00. 50 Economy ticket for £40 per person are available. Travel duration is 16h 20m
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Itabus5h 45m010:55SienaTrain Station16:40MilanLampugnano Bus Station0Premium EconomyA Bus from Itabus goes from Train Station, Siena (Italy) at 30/03/2026 10:55:00 to Lampugnano Bus Station, Milan (Italy) arriving at 30/03/2026 16:40:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 5h 45m
Waiting Time 3h 10m -
Best Price Offer: The price for the cheapest coach from Palermo to Milan is £32 on 25/03/2026. Flexible travellers save on ticket prices.
Frequency of bus connections between Palermo and Milan
Facts about coaches from Palermo to Milan
Compare all providers like FlixBus and Autoservizi Salemi that travel 3 times every day by bus from Palermo to Milan in one click! Book your bus ticket from Palermo to Milan starting from £32!
| Cheapest Bus | £32 |
| Fastest Bus | 20h 10m |
| Earliest Coach | 15:25 |
| Latest Coach | 18:00 |
| Daily Bus Connections | 3 Ø |
| Distance | 887.2 km |
| Coach Companies | FlixBus and Autoservizi Salemi |
Cheapest coach connections from Palermo to Milan
Every day, 3 buses from 2 coach companies leave Palermo for Milan: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 22/03/2026 and for the following days.
The cheapest time to travel from Palermo to Milan
How to save money travelling from Palermo to Milan
Book the ticket from Palermo to Milan in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Palermo to Milan, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Palermo to Milan are also emptier.All bus stations and stops in Palermo and Milan
The map below shows you where to find all the bus stations in Palermo and Milan.
Compare the bus with other modes of transport
Service and Comfort on the bus from Palermo to Milan
FAQs about the Palermo to Milan bus
How much does a Palermo - Milan coach trip cost?
How much could I save by comparing buses from Palermo to Milan?
How many connections are available for the Palermo - Milan route on average every day?
How long does a bus to Milan from Palermo take?
What time is the first bus from Palermo to Milan?
What time is the last coach from Palermo to Milan?
Which bus companies serve the Palermo - Milan route?
Is there a direct bus between Palermo and Milan?
What can I take with me on the bus to Milan from Palermo?
What equipment is available for the Palermo Milan bus route?
How does CheckMyBus find the best bus deals from Palermo to Milan?
How does CheckMyBus technology work for trips from Palermo to Milan?
Available seat classes which are offered on the bus route Palermo to Milan
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Palermo and to Milan
- Bus Routes to Palermo
- Coach from Agrigento to Palermo
- Bus to Palermo from Bari
- Buses Bologna to Palermo
- Coach from Caltagirone to Palermo
- Coach from Caltanissetta to Palermo
- Coach Florence to Palermo
- Coaches Genoa to Palermo
- Lamezia Terme to Palermo bus
- Licata to Palermo bus
- Bus from Marsala to Palermo
- Coaches Mazara del Vallo to Palermo
- Bus to Palermo from Milazzo
- Modica to Palermo coach
- Buses Naples to Palermo
- Bus from Piazza Armerina to Palermo
- Buses Porto Empedocle to Palermo
- Coach from Ragusa to Palermo
- Bus Siracusa to Palermo
- Bus to Palermo from Taranto
- Buses Trapani to Palermo
- Bus Routes to Milan
- Coach to Milan from Catanzaro
- Coach to Milan from Ciro Marina
- Bus Frascineto to Milan
- Hamburg to Milan bus
- Bus to Milan from Imperia
- Buses La Thuile to Milan
- Coaches Lauria to Milan
- Coach to Milan from Messina
- Coach to Milan from Perugia
- Coaches Pescara to Milan
- Rosarno to Milan coach
- Bus from Saint-Vincent to Milan
- Buses Sala Consilina to Milan
- Salerno to Milan bus
- San Severo to Milan coach
- Savona to Milan coach
- Bus to Milan from Soverato
- Coach to Milan from Taranto
- Coaches Trebisacce to Milan
- Vibo Valentia to Milan coach
