Which bus from Florence to Lyon is the best?
Check the bus schedule for Florence to Lyon. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or Itabus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 10h 40m | 12:00 | Florence | Villa Costanza Bus Station | 22:40 | Lyon | Perrache Bus Stop | Economy | £26 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 05/12/2025 12:00:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 22:40:00. 50 Economy ticket for £26 per person are available. Travel duration is 10h 40m
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| Itabus | 11h 50m | 01:05 | Florence | Villa Costanza Bus Station | 12:55 | Lyon | Perrache Bus Stop | Premium Economy | £35 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 05/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 12:55:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 11h 50m
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| Itabus | 11h 10m | 10:20 | Florence | Villa Costanza Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £35 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 05/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 21:30:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 11h 10m
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| Itabus | 12h 35m | 16:20 | Florence | Villa Costanza Bus Station | 04:55 | Lyon | Perrache Bus Stop | Premium Economy | £45 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 05/12/2025 16:20:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 04:55:00. 50 Premium Economy ticket for £45 per person are available. Travel duration is 12h 35m
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| FlixBus | 10h 40m | 07:30 | Florence | Villa Costanza Bus Station | 18:10 | Lyon | Perrache Bus Stop | Economy | £59 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 05/12/2025 07:30:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 18:10:00. 50 Economy ticket for £59 per person are available. Travel duration is 10h 40m
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11h 10mFlorence5 km10:20ScandicciBus Stop21:30LyonPerrache Bus Stop0 kmEconomyA Bus from goes from Bus Stop, Scandicci (Italy) at 05/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 21:30:00. 50 Economy ticket for £35 per person are available. Travel duration is 11h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 10h 40m | 12:00 | Florence | Villa Costanza Bus Station | 22:40 | Lyon | Perrache Bus Stop | Economy | £26 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 06/12/2025 12:00:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 22:40:00. 50 Economy ticket for £26 per person are available. Travel duration is 10h 40m
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| FlixBus | 11h 40m | 21:05 | Florence | Villa Costanza Bus Station | 08:45 | Lyon | Perrache Bus Stop | Economy | £26 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 06/12/2025 21:05:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 08:45:00. 50 Economy ticket for £26 per person are available. Travel duration is 11h 40m
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| Itabus | 12h 35m | 16:20 | Florence | Villa Costanza Bus Station | 04:55 | Lyon | Perrache Bus Stop | Premium Economy | £29 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 06/12/2025 16:20:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 04:55:00. 50 Premium Economy ticket for £29 per person are available. Travel duration is 12h 35m
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| Itabus | 11h 10m | 10:20 | Florence | Villa Costanza Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £31 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 06/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 21:30:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 11h 10m
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| Itabus | 15h 35m | 13:20 | Florence | Villa Costanza Bus Station | 04:55 | Lyon | Perrache Bus Stop | Premium Economy | £31 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 06/12/2025 13:20:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 04:55:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 15h 35m
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11h 10mFlorence5 km10:20ScandicciBus Stop21:30LyonPerrache Bus Stop0 kmEconomyA Bus from goes from Bus Stop, Scandicci (Italy) at 06/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 21:30:00. 50 Economy ticket for £35 per person are available. Travel duration is 11h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 10h 40m | 12:00 | Florence | Villa Costanza Bus Station | 22:40 | Lyon | Perrache Bus Stop | Economy | £26 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 07/12/2025 12:00:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 22:40:00. 50 Economy ticket for £26 per person are available. Travel duration is 10h 40m
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| FlixBus | 11h 40m | 21:05 | Florence | Villa Costanza Bus Station | 08:45 | Lyon | Perrache Bus Stop | Economy | £26 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 07/12/2025 21:05:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 08:45:00. 50 Economy ticket for £26 per person are available. Travel duration is 11h 40m
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| Itabus | 12h 35m | 16:20 | Florence | Villa Costanza Bus Station | 04:55 | Lyon | Perrache Bus Stop | Premium Economy | £30 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 07/12/2025 16:20:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 04:55:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 12h 35m
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| Itabus | 11h 50m | 01:05 | Florence | Villa Costanza Bus Station | 12:55 | Lyon | Perrache Bus Stop | Premium Economy | £31 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 07/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 12:55:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 11h 50m
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| Itabus | 11h 10m | 10:20 | Florence | Villa Costanza Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £31 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 07/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 21:30:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 11h 10m
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11h 10mFlorence5 km10:20ScandicciBus Stop21:30LyonPerrache Bus Stop0 kmEconomyA Bus from goes from Bus Stop, Scandicci (Italy) at 07/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 21:30:00. 50 Economy ticket for £35 per person are available. Travel duration is 11h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 11h 10m | 10:20 | Florence | Villa Costanza Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £31 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 08/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 21:30:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 11h 10m
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| Itabus | 11h 50m | 01:05 | Florence | Villa Costanza Bus Station | 12:55 | Lyon | Perrache Bus Stop | Premium Economy | £39 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 08/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 12:55:00. 50 Premium Economy ticket for £39 per person are available. Travel duration is 11h 50m
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| FlixBus | 10h 40m | 07:30 | Florence | Villa Costanza Bus Station | 18:10 | Lyon | Perrache Bus Stop | Economy | £45 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 08/12/2025 07:30:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 18:10:00. 50 Economy ticket for £45 per person are available. Travel duration is 10h 40m
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| Itabus | 15h 35m | 13:20 | Florence | Villa Costanza Bus Station | 04:55 | Lyon | Perrache Bus Stop | Premium Economy | £48 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 08/12/2025 13:20:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 04:55:00. 50 Premium Economy ticket for £48 per person are available. Travel duration is 15h 35m
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| FlixBus | 10h 40m | 12:00 | Florence | Villa Costanza Bus Station | 22:40 | Lyon | Perrache Bus Stop | Economy | £57 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 08/12/2025 12:00:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 22:40:00. 50 Economy ticket for £57 per person are available. Travel duration is 10h 40m
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11h 10mFlorence5 km10:20ScandicciBus Stop21:30LyonPerrache Bus Stop0 kmEconomyA Bus from goes from Bus Stop, Scandicci (Italy) at 08/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 21:30:00. 50 Economy ticket for £35 per person are available. Travel duration is 11h 10m
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Distribusion11h 10m010:20FlorenceVilla Costanza Bus Station16:55TurinCentral Bus Station0Premium EconomyA Bus from Distribusion goes from Villa Costanza Bus Station, Florence (Italy) at 06/12/2025 10:20:00 to Central Bus Station, Turin (Italy) arriving at 06/12/2025 16:55:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 35m
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Distribusion4h 30m017:00TurinCentral Bus Station21:30LyonPerrache Bus Stop0Premium EconomyA Bus from Distribusion goes from Central Bus Station, Turin (Italy) at 06/12/2025 17:00:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 21:30:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 4h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 10h 40m | 07:30 | Florence | Villa Costanza Bus Station | 18:10 | Lyon | Perrache Bus Stop | Economy | £24 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 09/12/2025 07:30:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 18:10:00. 50 Economy ticket for £24 per person are available. Travel duration is 10h 40m
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| Itabus | 11h 10m | 10:20 | Florence | Villa Costanza Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £31 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 09/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 21:30:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 11h 10m
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| FlixBus | 11h 15m | 12:30 | Florence | Villa Costanza Bus Station | 23:45 | Lyon | Perrache Bus Stop | Economy | £40 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 09/12/2025 12:30:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 23:45:00. 50 Economy ticket for £40 per person are available. Travel duration is 11h 15m
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| Itabus | 11h 50m | 01:05 | Florence | Villa Costanza Bus Station | 12:55 | Lyon | Perrache Bus Stop | Premium Economy | £45 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 09/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 12:55:00. 50 Premium Economy ticket for £45 per person are available. Travel duration is 11h 50m
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| FlixBus | 12h 20m | 23:40 | Florence | Piazzale Montelungo Coach Stop | 12:00 | Lyon | Perrache Bus Stop | Economy | £52 |
A Bus from FlixBus goes from Piazzale Montelungo Coach Stop, Florence (Italy) at 09/12/2025 23:40:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 12:00:00. 50 Economy ticket for £52 per person are available. Travel duration is 12h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 11h 40m | 21:05 | Florence | Villa Costanza Bus Station | 08:45 | Lyon | Perrache Bus Stop | Economy | £18 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/12/2025 21:05:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 08:45:00. 50 Economy ticket for £18 per person are available. Travel duration is 11h 40m
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| FlixBus | 10h 40m | 07:30 | Florence | Villa Costanza Bus Station | 18:10 | Lyon | Perrache Bus Stop | Economy | £23 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/12/2025 07:30:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 18:10:00. 50 Economy ticket for £23 per person are available. Travel duration is 10h 40m
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| FlixBus | 11h 50m | 18:45 | Florence | Villa Costanza Bus Station | 06:35 | Lyon | Perrache Bus Stop | Economy | £29 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 10/12/2025 18:45:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 06:35:00. 50 Economy ticket for £29 per person are available. Travel duration is 11h 50m
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| Itabus | 11h 50m | 01:05 | Florence | Villa Costanza Bus Station | 12:55 | Lyon | Perrache Bus Stop | Premium Economy | £31 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 10/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 12:55:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 11h 50m
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| Itabus | 11h 10m | 10:20 | Florence | Villa Costanza Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £31 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 10/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 21:30:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 11h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 10h 40m | 12:00 | Florence | Villa Costanza Bus Station | 22:40 | Lyon | Perrache Bus Stop | Economy | £20 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 11/12/2025 12:00:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 22:40:00. 50 Economy ticket for £20 per person are available. Travel duration is 10h 40m
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| FlixBus | 10h 40m | 07:30 | Florence | Villa Costanza Bus Station | 18:10 | Lyon | Perrache Bus Stop | Economy | £21 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 11/12/2025 07:30:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 18:10:00. 50 Economy ticket for £21 per person are available. Travel duration is 10h 40m
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| Itabus | 11h 10m | 10:20 | Florence | Villa Costanza Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £21 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 11/12/2025 10:20:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 21:30:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 11h 10m
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| FlixBus | 11h 50m | 18:45 | Florence | Villa Costanza Bus Station | 06:35 | Lyon | Perrache Bus Stop | Economy | £22 |
A Bus from FlixBus goes from Villa Costanza Bus Station, Florence (Italy) at 11/12/2025 18:45:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 06:35:00. 50 Economy ticket for £22 per person are available. Travel duration is 11h 50m
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| Itabus | 11h 50m | 01:05 | Florence | Villa Costanza Bus Station | 12:55 | Lyon | Perrache Bus Stop | Premium Economy | £26 |
A Bus from Itabus goes from Villa Costanza Bus Station, Florence (Italy) at 11/12/2025 01:05:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 12:55:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 11h 50m
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Best Price Offer: The price for the cheapest coach from Florence to Lyon is £16 on 11/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Florence and Lyon?
All facts for Florence to Lyon bus at a glance
Compare all coach operators like FlixBus and Itabus that travel daily 22 times by bus from Florence to Lyon in one click. Book your Florence to Lyon bus ticket starting from £16!
| Cheapest Bus | £16 |
| Fastest Bus | 10h 40m |
| Earliest Coach | 00:05 |
| Latest Coach | 23:40 |
| Daily Bus Connections | 22 Ø |
| Distance | 552.2 km |
| Coach Companies | FlixBus and Itabus |
What are the cheapest coach tickets from Florence to Lyon?
Every day, 22 buses from 2 coach companies leave Florence for Lyon. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Florence to Lyon
How to save money travelling from Florence to Lyon
Book the ticket from Florence to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Florence to Lyon, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Florence to Lyon are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Florence and Lyon
Here is a map with all coach stations in Florence and Lyon. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Florence to Lyon
FAQs for Florence to Lyon bus
How much does a Florence Lyon coach trip cost?
How much could I save by comparing buses from Florence to Lyon?
How many connections are available for the Florence Lyon route on average every day?
How long does a bus to Lyon from Florence take?
What time is the first bus from Florence to Lyon?
What time is the last coach from Florence to Lyon?
Which bus companies serve the Florence Lyon route?
Is there a direct bus between Florence and Lyon?
What can I take with me on the bus to Lyon from Florence?
What equipment is available for the Florence Lyon bus route?
Available seat classes which are offered on the bus route Florence to Lyon
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
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