Which bus from Lyon to Madrid is the best?
Check the bus schedule for Lyon to Madrid. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus, BlaBlaCar Bus or ALSA. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 16h 55m | 05:10 | Lyon | Perrache Bus Stop | 22:05 | Madrid | Avenida de América Coach Station | Economy | £49 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 05/12/2025 05:10:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 05/12/2025 22:05:00. 50 Economy ticket for £49 per person are available. Travel duration is 16h 55m
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| BlaBlaCar Bus | 22h 25m | 16:45 | Lyon | Perrache Train Station | 15:10 | Madrid | Sur Bus Station | Economy | £51 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 05/12/2025 16:45:00 to Sur Bus Station, Madrid (Spain) arriving at 06/12/2025 15:10:00. 50 Economy ticket for £51 per person are available. Travel duration is 22h 25m
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| Union Ivkoni | 22h 45m | 14:15 | Lyon | Perrache Bus Stop | 13:00 | Madrid | Mendez Alvaro Train Station | Basic | £65 |
A Bus from Union Ivkoni goes from Perrache Bus Stop, Lyon (France) at 05/12/2025 14:15:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 06/12/2025 13:00:00. 50 Basic ticket for £65 per person are available. Travel duration is 22h 45m
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| BlaBlaCar Bus | 19h 25m | 05:15 | Lyon | Perrache Train Station | 00:40 | Madrid | Sur Bus Station | Economy | £66 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 05/12/2025 05:15:00 to Sur Bus Station, Madrid (Spain) arriving at 06/12/2025 00:40:00. 50 Economy ticket for £66 per person are available. Travel duration is 19h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 22h 25m | 16:45 | Lyon | Perrache Train Station | 15:10 | Madrid | Sur Bus Station | Economy | £52 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 06/12/2025 16:45:00 to Sur Bus Station, Madrid (Spain) arriving at 07/12/2025 15:10:00. 50 Economy ticket for £52 per person are available. Travel duration is 22h 25m
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| BlaBlaCar Bus | 19h 25m | 05:15 | Lyon | Perrache Train Station | 00:40 | Madrid | Sur Bus Station | Economy | £61 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 06/12/2025 05:15:00 to Sur Bus Station, Madrid (Spain) arriving at 07/12/2025 00:40:00. 50 Economy ticket for £61 per person are available. Travel duration is 19h 25m
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| ALSA | 19h 30m | 20:30 | Lyon | Perrache Bus Stop | 16:00 | Madrid | Mendez Alvaro Train Station | Economy | £62 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 06/12/2025 20:30:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 07/12/2025 16:00:00. 50 Economy ticket for £62 per person are available. Travel duration is 19h 30m
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| FlixBus | 16h 40m | 16:00 | Lyon | Perrache Bus Stop | 08:40 | Madrid | Sur Bus Station | Economy | £73 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 06/12/2025 16:00:00 to Sur Bus Station, Madrid (Spain) arriving at 07/12/2025 08:40:00. 50 Economy ticket for £73 per person are available. Travel duration is 16h 40m
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| FlixBus | 19h 20m | 14:55 | Lyon | Perrache Bus Stop | 10:15 | Madrid | Sur Bus Station | Economy | £79 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 06/12/2025 14:55:00 to Sur Bus Station, Madrid (Spain) arriving at 07/12/2025 10:15:00. 50 Economy ticket for £79 per person are available. Travel duration is 19h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 20h 0m | 04:40 | Lyon | Perrache Train Station | 00:40 | Madrid | Sur Bus Station | Economy | £68 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 07/12/2025 04:40:00 to Sur Bus Station, Madrid (Spain) arriving at 08/12/2025 00:40:00. 50 Economy ticket for £68 per person are available. Travel duration is 20h 0m
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| BlaBlaCar Bus | 17h 15m | 20:50 | Lyon | Perrache Train Station | 14:05 | Madrid | Sur Bus Station | Economy | £87 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 07/12/2025 20:50:00 to Sur Bus Station, Madrid (Spain) arriving at 08/12/2025 14:05:00. 50 Economy ticket for £87 per person are available. Travel duration is 17h 15m
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| BlaBlaCar Bus | 22h 25m | 16:45 | Lyon | Perrache Train Station | 15:10 | Madrid | Sur Bus Station | Economy | £135 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 07/12/2025 16:45:00 to Sur Bus Station, Madrid (Spain) arriving at 08/12/2025 15:10:00. 50 Economy ticket for £135 per person are available. Travel duration is 22h 25m
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Busbud18h 35m005:10LyonPerrache Bus Stop22:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Bus from Busbud goes from Perrache Bus Stop, Lyon (France) at 09/12/2025 05:10:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 09/12/2025 22:35:00. 50 Economy ticket for £40 per person are available. Travel duration is 17h 25m
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Bookaway0h 15m023:30Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T423:45MadridMetro O Donnell Bus Stop0BasicA Bus from Bookaway goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 09/12/2025 23:30:00 to Metro O Donnell Bus Stop, Madrid (Spain) arriving at 09/12/2025 23:45:00. 50 Basic ticket for £6 per person are available. Travel duration is 0h 15m
Waiting Time 0h 55m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 16h 40m | 16:00 | Lyon | Perrache Bus Stop | 08:40 | Madrid | Sur Bus Station | Economy | £93 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 08/12/2025 16:00:00 to Sur Bus Station, Madrid (Spain) arriving at 09/12/2025 08:40:00. 50 Economy ticket for £93 per person are available. Travel duration is 16h 40m
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Busbud19h 40m005:10LyonPerrache Bus Stop22:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Bus from Busbud goes from Perrache Bus Stop, Lyon (France) at 09/12/2025 05:10:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 09/12/2025 22:35:00. 50 Economy ticket for £40 per person are available. Travel duration is 17h 25m
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Terravision0h 20m000:30Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T400:50MadridPuerta de Alcalá0EconomyA Bus from Terravision goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/12/2025 00:30:00 to Puerta de Alcalá, Madrid (Spain) arriving at 10/12/2025 00:50:00. 50 Economy ticket for £6 per person are available. Travel duration is 0h 20m
Waiting Time 1h 55m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 16h 40m | 16:00 | Lyon | Perrache Bus Stop | 08:40 | Madrid | Sur Bus Station | Economy | £75 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 09/12/2025 16:00:00 to Sur Bus Station, Madrid (Spain) arriving at 10/12/2025 08:40:00. 50 Economy ticket for £75 per person are available. Travel duration is 16h 40m
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| FlixBus | 19h 0m | 15:15 | Lyon | Perrache Bus Stop | 10:15 | Madrid | Sur Bus Station | Economy | £99 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 09/12/2025 15:15:00 to Sur Bus Station, Madrid (Spain) arriving at 10/12/2025 10:15:00. 50 Economy ticket for £99 per person are available. Travel duration is 19h 0m
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| FlixBus | 22h 35m | 11:40 | Lyon | Perrache Bus Stop | 10:15 | Madrid | Sur Bus Station | Economy | £100 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 09/12/2025 11:40:00 to Sur Bus Station, Madrid (Spain) arriving at 10/12/2025 10:15:00. 50 Economy ticket for £100 per person are available. Travel duration is 22h 35m
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| FlixBus | 19h 50m | 14:25 | Lyon | Perrache Bus Stop | 10:15 | Madrid | Sur Bus Station | Economy | £102 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 09/12/2025 14:25:00 to Sur Bus Station, Madrid (Spain) arriving at 10/12/2025 10:15:00. 50 Economy ticket for £102 per person are available. Travel duration is 19h 50m
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Busbud19h 40m005:10LyonPerrache Bus Stop22:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Bus from Busbud goes from Perrache Bus Stop, Lyon (France) at 09/12/2025 05:10:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 09/12/2025 22:35:00. 50 Economy ticket for £40 per person are available. Travel duration is 17h 25m
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Terravision0h 20m000:30Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T400:50MadridPuerta de Alcalá0EconomyA Bus from Terravision goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 10/12/2025 00:30:00 to Puerta de Alcalá, Madrid (Spain) arriving at 10/12/2025 00:50:00. 50 Economy ticket for £6 per person are available. Travel duration is 0h 20m
Waiting Time 1h 55m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Union Ivkoni | 23h 0m | 14:15 | Lyon | Perrache Bus Stop | 13:15 | Madrid | Mendez Alvaro Train Station | Basic | £44 |
A Bus from Union Ivkoni goes from Perrache Bus Stop, Lyon (France) at 10/12/2025 14:15:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 11/12/2025 13:15:00. 50 Basic ticket for £44 per person are available. Travel duration is 23h 0m
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| FlixBus | 16h 40m | 16:00 | Lyon | Perrache Bus Stop | 08:40 | Madrid | Sur Bus Station | Economy | £56 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 10/12/2025 16:00:00 to Sur Bus Station, Madrid (Spain) arriving at 11/12/2025 08:40:00. 50 Economy ticket for £56 per person are available. Travel duration is 16h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 19h 30m | 20:30 | Lyon | Perrache Bus Stop | 16:00 | Madrid | Mendez Alvaro Train Station | Economy | £62 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 11/12/2025 20:30:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 12/12/2025 16:00:00. 50 Economy ticket for £62 per person are available. Travel duration is 19h 30m
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| FlixBus | 16h 40m | 16:00 | Lyon | Perrache Bus Stop | 08:40 | Madrid | Sur Bus Station | Economy | £65 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 11/12/2025 16:00:00 to Sur Bus Station, Madrid (Spain) arriving at 12/12/2025 08:40:00. 50 Economy ticket for £65 per person are available. Travel duration is 16h 40m
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| FlixBus | 20h 15m | 14:00 | Lyon | Perrache Bus Stop | 10:15 | Madrid | Sur Bus Station | Economy | £86 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 11/12/2025 14:00:00 to Sur Bus Station, Madrid (Spain) arriving at 12/12/2025 10:15:00. 50 Economy ticket for £86 per person are available. Travel duration is 20h 15m
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| FlixBus | 19h 0m | 15:15 | Lyon | Perrache Bus Stop | 10:15 | Madrid | Sur Bus Station | Economy | £86 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 11/12/2025 15:15:00 to Sur Bus Station, Madrid (Spain) arriving at 12/12/2025 10:15:00. 50 Economy ticket for £86 per person are available. Travel duration is 19h 0m
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FlixBus18h 40m014:00LyonPerrache Bus Stop21:40ToulouseCentral Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 12/12/2025 14:00:00 to Central Bus Station, Toulouse (France) arriving at 12/12/2025 21:40:00. 50 Economy ticket for £18 per person are available. Travel duration is 7h 40m
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FlixBus9h 45m022:55ToulouseCentral Bus Station08:40MadridSur Bus Station0EconomyA Bus from FlixBus goes from Central Bus Station, Toulouse (France) at 12/12/2025 22:55:00 to Sur Bus Station, Madrid (Spain) arriving at 13/12/2025 08:40:00. 50 Economy ticket for £25 per person are available. Travel duration is 9h 45m
Waiting Time 1h 15m -
Best Price Offer: The price for the cheapest coach from Lyon to Madrid is £37 on 26/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Lyon and Madrid?
All facts for Lyon to Madrid bus at a glance
Compare all coach operators like FlixBus, BlaBlaCar Bus and ALSA that travel daily 5 times by bus from Lyon to Madrid in one click. Book your Lyon to Madrid bus ticket starting from £37!
| Cheapest Bus | £37 |
| Fastest Bus | 16h 40m |
| Earliest Coach | 05:10 |
| Latest Coach | 20:30 |
| Daily Bus Connections | 5 Ø |
| Distance | 912.1 km |
| Coach Companies | FlixBus, BlaBlaCar Bus, ALSA and Union Ivkoni |
What are the cheapest coach tickets from Lyon to Madrid?
Every day, 5 buses from 4 coach companies leave Lyon for Madrid. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Lyon to Madrid
How to save money travelling from Lyon to Madrid
Book the ticket from Lyon to Madrid in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Lyon to Madrid, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Lyon to Madrid are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
Latest reviews for coach companies on the route Lyon - Madrid
All bus stations and stops in Lyon and Madrid
Here is a map with all coach stations in Lyon and Madrid. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Lyon to Madrid
FAQs for Lyon to Madrid bus
How much does a Lyon Madrid coach trip cost?
How much could I save by comparing buses from Lyon to Madrid?
How many connections are available for the Lyon Madrid route on average every day?
How long does a bus to Madrid from Lyon take?
What time is the first bus from Lyon to Madrid?
What time is the last coach from Lyon to Madrid?
Which bus companies serve the Lyon Madrid route?
Is there a direct bus between Lyon and Madrid?
What can I take with me on the bus to Madrid from Lyon?
What equipment is available for the Lyon Madrid bus route?
Available seat classes which are offered on the bus route Lyon to Madrid
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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