Which bus from Lyon to Madrid is the best?
Check the bus schedule for Lyon to Madrid. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus, ALSA or BlaBlaCar Bus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 17h 15m | 20:50 | Lyon | Perrache Bus Stop | 14:05 | Madrid | Mendez Alvaro Train Station | Economy | £47 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 18/03/2026 20:50:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 19/03/2026 14:05:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 15m
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| Union Ivkoni | 23h 0m | 14:15 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 13:15 | Madrid | Mendez Alvaro Train Station | Basic | £48 |
A Bus from Union Ivkoni goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 18/03/2026 14:15:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 19/03/2026 13:15:00. 50 Basic ticket for £48 per person are available. Travel duration is 23h 0m
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ALSA18h 35m005:15LyonPerrache Bus Stop23:05Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 20/03/2026 05:15:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 20/03/2026 23:05:00. 50 Economy ticket for £35 per person are available. Travel duration is 17h 50m
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Terravision0h 20m023:30Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T423:50MadridPuerta de Alcalá0EconomyA Bus from Terravision goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 20/03/2026 23:30:00 to Puerta de Alcalá, Madrid (Spain) arriving at 20/03/2026 23:50:00. 50 Economy ticket for £6 per person are available. Travel duration is 0h 20m
Waiting Time 0h 25m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 17h 55m | 22:50 | Lyon | Perrache Bus Stop | 16:45 | Madrid | Mendez Alvaro Train Station | Economy | £47 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 19/03/2026 22:50:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 20/03/2026 16:45:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 55m
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| FlixBus | 16h 40m | 16:00 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 08:40 | Madrid | Sur Bus Station | Economy | £64 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 19/03/2026 16:00:00 to Sur Bus Station, Madrid (Spain) arriving at 20/03/2026 08:40:00. 50 Economy ticket for £64 per person are available. Travel duration is 16h 40m
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| FlixBus | 19h 50m | 14:25 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 10:15 | Madrid | Sur Bus Station | Economy | £85 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 19/03/2026 14:25:00 to Sur Bus Station, Madrid (Spain) arriving at 20/03/2026 10:15:00. 50 Economy ticket for £85 per person are available. Travel duration is 19h 50m
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| FlixBus | 19h 0m | 15:15 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 10:15 | Madrid | Sur Bus Station | Economy | £86 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 19/03/2026 15:15:00 to Sur Bus Station, Madrid (Spain) arriving at 20/03/2026 10:15:00. 50 Economy ticket for £86 per person are available. Travel duration is 19h 0m
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| ALSA | 20h 15m | 20:30 | Lyon | Perrache Bus Stop | 16:45 | Madrid | Mendez Alvaro Train Station | Economy | £94 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 19/03/2026 20:30:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 20/03/2026 16:45:00. 50 Economy ticket for £94 per person are available. Travel duration is 20h 15m
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ALSA19h 30m005:15LyonPerrache Bus Stop22:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 21/03/2026 05:15:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 21/03/2026 22:35:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 20m
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EMT Madrid0h 15m000:30Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T400:45MadridMetro O Donnell Bus Stop0BasicA Bus from EMT Madrid goes from Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) at 22/03/2026 00:30:00 to Metro O Donnell Bus Stop, Madrid (Spain) arriving at 22/03/2026 00:45:00. 50 Basic ticket for £7 per person are available. Travel duration is 0h 15m
Waiting Time 1h 55m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 16h 40m | 16:30 | Lyon | Perrache Bus Stop | 09:10 | Madrid | Mendez Alvaro Train Station | Economy | £37 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 20/03/2026 16:30:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 21/03/2026 09:10:00. 50 Economy ticket for £37 per person are available. Travel duration is 16h 40m
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| BlaBlaCar Bus | 17h 10m | 20:55 | Lyon | Perrache Train Station | 14:05 | Madrid | Sur Bus Station | Economy | £45 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 20/03/2026 20:55:00 to Sur Bus Station, Madrid (Spain) arriving at 21/03/2026 14:05:00. 50 Economy ticket for £45 per person are available. Travel duration is 17h 10m
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| FlixBus | 17h 35m | 21:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 15:25 | Madrid | Sur Bus Station | Economy | £46 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 20/03/2026 21:50:00 to Sur Bus Station, Madrid (Spain) arriving at 21/03/2026 15:25:00. 50 Economy ticket for £46 per person are available. Travel duration is 17h 35m
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| Union Ivkoni | 22h 45m | 14:15 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 13:00 | Madrid | Mendez Alvaro Train Station | Basic | £48 |
A Bus from Union Ivkoni goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 20/03/2026 14:15:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 21/03/2026 13:00:00. 50 Basic ticket for £48 per person are available. Travel duration is 22h 45m
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| Internorte Transportes | 16h 20m | 16:30 | Lyon | Part-Dieu Train Station | 08:50 | Madrid | Benavente Coach Station | Basic | £108 |
A Bus from Internorte Transportes goes from Part-Dieu Train Station, Lyon (France) at 20/03/2026 16:30:00 to Benavente Coach Station, Madrid (Spain) arriving at 21/03/2026 08:50:00. 50 Basic ticket for £108 per person are available. Travel duration is 16h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 16h 40m | 16:30 | Lyon | Perrache Bus Stop | 09:10 | Madrid | Mendez Alvaro Train Station | Economy | £37 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 21/03/2026 16:30:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 22/03/2026 09:10:00. 50 Economy ticket for £37 per person are available. Travel duration is 16h 40m
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| FlixBus | 17h 35m | 21:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 15:25 | Madrid | Sur Bus Station | Economy | £39 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 21/03/2026 21:50:00 to Sur Bus Station, Madrid (Spain) arriving at 22/03/2026 15:25:00. 50 Economy ticket for £39 per person are available. Travel duration is 17h 35m
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| ALSA | 17h 55m | 22:50 | Lyon | Perrache Bus Stop | 16:45 | Madrid | Mendez Alvaro Train Station | Economy | £47 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 21/03/2026 22:50:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 22/03/2026 16:45:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 55m
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| FlixBus | 22h 35m | 09:20 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 07:55 | Madrid | Sur Bus Station | Economy | £50 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 21/03/2026 09:20:00 to Sur Bus Station, Madrid (Spain) arriving at 22/03/2026 07:55:00. 50 Economy ticket for £50 per person are available. Travel duration is 22h 35m
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| BlaBlaCar Bus | 19h 20m | 05:20 | Lyon | Perrache Train Station | 00:40 | Madrid | Sur Bus Station | Economy | £56 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 21/03/2026 05:20:00 to Sur Bus Station, Madrid (Spain) arriving at 22/03/2026 00:40:00. 50 Economy ticket for £56 per person are available. Travel duration is 19h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 16h 40m | 16:30 | Lyon | Perrache Bus Stop | 09:10 | Madrid | Mendez Alvaro Train Station | Economy | £37 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 22/03/2026 16:30:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 23/03/2026 09:10:00. 50 Economy ticket for £37 per person are available. Travel duration is 16h 40m
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| Union Ivkoni | 22h 15m | 15:00 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 13:15 | Madrid | Mendez Alvaro Train Station | Basic | £41 |
A Bus from Union Ivkoni goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 22/03/2026 15:00:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 23/03/2026 13:15:00. 50 Basic ticket for £41 per person are available. Travel duration is 22h 15m
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| ALSA | 17h 15m | 20:50 | Lyon | Perrache Bus Stop | 14:05 | Madrid | Mendez Alvaro Train Station | Economy | £47 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 22/03/2026 20:50:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 23/03/2026 14:05:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 15m
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| FlixBus | 17h 35m | 21:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 15:25 | Madrid | Sur Bus Station | Economy | £49 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 22/03/2026 21:50:00 to Sur Bus Station, Madrid (Spain) arriving at 23/03/2026 15:25:00. 50 Economy ticket for £49 per person are available. Travel duration is 17h 35m
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| BlaBlaCar Bus | 17h 10m | 20:55 | Lyon | Perrache Train Station | 14:05 | Madrid | Sur Bus Station | Economy | £52 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 22/03/2026 20:55:00 to Sur Bus Station, Madrid (Spain) arriving at 23/03/2026 14:05:00. 50 Economy ticket for £52 per person are available. Travel duration is 17h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 16h 40m | 16:30 | Lyon | Perrache Bus Stop | 09:10 | Madrid | Mendez Alvaro Train Station | Economy | £37 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 23/03/2026 16:30:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 24/03/2026 09:10:00. 50 Economy ticket for £37 per person are available. Travel duration is 16h 40m
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| FlixBus | 17h 35m | 21:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 15:25 | Madrid | Sur Bus Station | Economy | £43 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 21:50:00 to Sur Bus Station, Madrid (Spain) arriving at 24/03/2026 15:25:00. 50 Economy ticket for £43 per person are available. Travel duration is 17h 35m
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| FlixBus | 22h 35m | 09:20 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 07:55 | Madrid | Sur Bus Station | Economy | £50 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 09:20:00 to Sur Bus Station, Madrid (Spain) arriving at 24/03/2026 07:55:00. 50 Economy ticket for £50 per person are available. Travel duration is 22h 35m
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| BlaBlaCar Bus | 19h 20m | 05:20 | Lyon | Perrache Train Station | 00:40 | Madrid | Sur Bus Station | Economy | £56 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 23/03/2026 05:20:00 to Sur Bus Station, Madrid (Spain) arriving at 24/03/2026 00:40:00. 50 Economy ticket for £56 per person are available. Travel duration is 19h 20m
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| BlaBlaCar Bus | 19h 45m | 14:00 | Lyon | Perrache Train Station | 09:45 | Madrid | Sur Bus Station | Economy | £60 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 23/03/2026 14:00:00 to Sur Bus Station, Madrid (Spain) arriving at 24/03/2026 09:45:00. 50 Economy ticket for £60 per person are available. Travel duration is 19h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
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| FlixBus | 22h 35m | 09:20 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 07:55 | Madrid | Sur Bus Station | Economy | £41 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 09:20:00 to Sur Bus Station, Madrid (Spain) arriving at 25/03/2026 07:55:00. 50 Economy ticket for £41 per person are available. Travel duration is 22h 35m
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| FlixBus | 17h 35m | 21:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 15:25 | Madrid | Sur Bus Station | Economy | £41 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 21:50:00 to Sur Bus Station, Madrid (Spain) arriving at 25/03/2026 15:25:00. 50 Economy ticket for £41 per person are available. Travel duration is 17h 35m
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| FlixBus | 16h 40m | 16:00 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 08:40 | Madrid | Sur Bus Station | Economy | £54 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 16:00:00 to Sur Bus Station, Madrid (Spain) arriving at 25/03/2026 08:40:00. 50 Economy ticket for £54 per person are available. Travel duration is 16h 40m
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| FlixBus | 22h 30m | 11:45 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 10:15 | Madrid | Sur Bus Station | Economy | £64 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 11:45:00 to Sur Bus Station, Madrid (Spain) arriving at 25/03/2026 10:15:00. 50 Economy ticket for £64 per person are available. Travel duration is 22h 30m
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| FlixBus | 19h 50m | 14:25 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 10:15 | Madrid | Sur Bus Station | Economy | £64 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 14:25:00 to Sur Bus Station, Madrid (Spain) arriving at 25/03/2026 10:15:00. 50 Economy ticket for £64 per person are available. Travel duration is 19h 50m
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Best Price Offer: The price for the cheapest coach from Lyon to Madrid is £35 on 27/03/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Lyon and Madrid?
All facts for Lyon to Madrid bus at a glance
Compare all coach operators like FlixBus, ALSA and BlaBlaCar Bus that travel daily 10 times by bus from Lyon to Madrid in one click. Book your Lyon to Madrid bus ticket starting from £35!
| Cheapest Bus | £35 |
| Fastest Bus | 16h 20m |
| Earliest Coach | 14:15 |
| Latest Coach | 21:50 |
| Daily Bus Connections | 10 Ø |
| Distance | 912.1 km |
| Coach Companies | FlixBus, ALSA, BlaBlaCar Bus, Internorte Transportes and Union Ivkoni |
What are the cheapest coach tickets from Lyon to Madrid?
Every day, 10 buses from 5 coach companies leave Lyon for Madrid. Check the table below to find the cheapest prices for coach tickets for this route, starting from 18/03/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Lyon to Madrid
How to save money travelling from Lyon to Madrid
Book the ticket from Lyon to Madrid in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Lyon to Madrid, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Lyon to Madrid are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
Latest reviews for coach companies on the route Lyon - Madrid
All bus stations and stops in Lyon and Madrid
Here is a map with all coach stations in Lyon and Madrid. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Lyon to Madrid
FAQs for Lyon to Madrid bus
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Available seat classes which are offered on the bus route Lyon to Madrid
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Lyon and to Madrid
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