Which bus from Lyon to Madrid is the best?
Check the bus schedule for Lyon to Madrid. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus, ALSA or BlaBlaCar Bus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 17h 55m | 22:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 16:45 | Madrid | Mendez Alvaro Train Station | Economy | £34 |
A Bus from ALSA goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 02/05/2026 22:50:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 03/05/2026 16:45:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 55m
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| ALSA | 17h 25m | 16:30 | Lyon | Perrache Bus Stop | 09:55 | Madrid | Mendez Alvaro Train Station | Economy | £37 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 02/05/2026 16:30:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 03/05/2026 09:55:00. 50 Economy ticket for £37 per person are available. Travel duration is 17h 25m
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| BlaBlaCar Bus | 19h 20m | 05:20 | Lyon | Perrache Train Station | 00:40 | Madrid | Sur Bus Station | Economy | £68 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 02/05/2026 05:20:00 to Sur Bus Station, Madrid (Spain) arriving at 03/05/2026 00:40:00. 50 Economy ticket for £68 per person are available. Travel duration is 19h 20m
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| FlixBus | 17h 45m | 21:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 15:35 | Madrid | Sur Bus Station | Economy | £68 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 02/05/2026 21:50:00 to Sur Bus Station, Madrid (Spain) arriving at 03/05/2026 15:35:00. 50 Economy ticket for £68 per person are available. Travel duration is 17h 45m
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| FlixBus | 16h 40m | 16:00 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 08:40 | Madrid | Sur Bus Station | Economy | £72 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 02/05/2026 16:00:00 to Sur Bus Station, Madrid (Spain) arriving at 03/05/2026 08:40:00. 50 Economy ticket for £72 per person are available. Travel duration is 16h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 17h 55m | 22:50 | Lyon | Perrache Bus Stop | 16:45 | Madrid | Mendez Alvaro Train Station | Economy | £47 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 03/05/2026 22:50:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 04/05/2026 16:45:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 55m
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| ALSA | 17h 15m | 20:50 | Lyon | Perrache Bus Stop | 14:05 | Madrid | Mendez Alvaro Train Station | Economy | £47 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 03/05/2026 20:50:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 04/05/2026 14:05:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 15m
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| FlixBus | 17h 45m | 21:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 15:35 | Madrid | Sur Bus Station | Economy | £65 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 03/05/2026 21:50:00 to Sur Bus Station, Madrid (Spain) arriving at 04/05/2026 15:35:00. 50 Economy ticket for £65 per person are available. Travel duration is 17h 45m
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| BlaBlaCar Bus | 17h 10m | 20:55 | Lyon | Perrache Train Station | 14:05 | Madrid | Sur Bus Station | Economy | £78 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 03/05/2026 20:55:00 to Sur Bus Station, Madrid (Spain) arriving at 04/05/2026 14:05:00. 50 Economy ticket for £78 per person are available. Travel duration is 17h 10m
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| BlaBlaCar Bus | 19h 20m | 05:20 | Lyon | Perrache Train Station | 00:40 | Madrid | Sur Bus Station | Economy | £80 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 03/05/2026 05:20:00 to Sur Bus Station, Madrid (Spain) arriving at 04/05/2026 00:40:00. 50 Economy ticket for £80 per person are available. Travel duration is 19h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 17h 25m | 16:30 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 09:55 | Madrid | Mendez Alvaro Train Station | Economy | £34 |
A Bus from ALSA goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 04/05/2026 16:30:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 05/05/2026 09:55:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 25m
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| FlixBus | 17h 45m | 21:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 15:35 | Madrid | Sur Bus Station | Economy | £47 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 04/05/2026 21:50:00 to Sur Bus Station, Madrid (Spain) arriving at 05/05/2026 15:35:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 45m
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| BlaBlaCar Bus | 23h 10m | 16:00 | Lyon | Perrache Train Station | 15:10 | Madrid | Sur Bus Station | Economy | £60 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 04/05/2026 16:00:00 to Sur Bus Station, Madrid (Spain) arriving at 05/05/2026 15:10:00. 50 Economy ticket for £60 per person are available. Travel duration is 23h 10m
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| FlixBus | 16h 40m | 16:00 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 08:40 | Madrid | Sur Bus Station | Economy | £60 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 04/05/2026 16:00:00 to Sur Bus Station, Madrid (Spain) arriving at 05/05/2026 08:40:00. 50 Economy ticket for £60 per person are available. Travel duration is 16h 40m
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| BlaBlaCar Bus | 19h 20m | 05:20 | Lyon | Perrache Train Station | 00:40 | Madrid | Sur Bus Station | Economy | £68 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 04/05/2026 05:20:00 to Sur Bus Station, Madrid (Spain) arriving at 05/05/2026 00:40:00. 50 Economy ticket for £68 per person are available. Travel duration is 19h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 17h 25m | 16:30 | Lyon | Perrache Bus Stop | 09:55 | Madrid | Mendez Alvaro Train Station | Economy | £37 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 05/05/2026 16:30:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 06/05/2026 09:55:00. 50 Economy ticket for £37 per person are available. Travel duration is 17h 25m
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| ALSA | 17h 55m | 22:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 16:45 | Madrid | Mendez Alvaro Train Station | Economy | £42 |
A Bus from ALSA goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 05/05/2026 22:50:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 06/05/2026 16:45:00. 50 Economy ticket for £42 per person are available. Travel duration is 17h 55m
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| FlixBus | 16h 40m | 16:00 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 08:40 | Madrid | Sur Bus Station | Economy | £45 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 05/05/2026 16:00:00 to Sur Bus Station, Madrid (Spain) arriving at 06/05/2026 08:40:00. 50 Economy ticket for £45 per person are available. Travel duration is 16h 40m
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| FlixBus | 17h 45m | 21:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 15:35 | Madrid | Sur Bus Station | Economy | £46 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 05/05/2026 21:50:00 to Sur Bus Station, Madrid (Spain) arriving at 06/05/2026 15:35:00. 50 Economy ticket for £46 per person are available. Travel duration is 17h 45m
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| BlaBlaCar Bus | 20h 0m | 04:40 | Lyon | Perrache Train Station | 00:40 | Madrid | Sur Bus Station | Economy | £68 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 05/05/2026 04:40:00 to Sur Bus Station, Madrid (Spain) arriving at 06/05/2026 00:40:00. 50 Economy ticket for £68 per person are available. Travel duration is 20h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 17h 25m | 16:30 | Lyon | Perrache Bus Stop | 09:55 | Madrid | Mendez Alvaro Train Station | Economy | £37 |
A Bus from ALSA goes from Perrache Bus Stop, Lyon (France) at 06/05/2026 16:30:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 07/05/2026 09:55:00. 50 Economy ticket for £37 per person are available. Travel duration is 17h 25m
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| ALSA | 17h 15m | 20:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 14:05 | Madrid | Mendez Alvaro Train Station | Economy | £42 |
A Bus from ALSA goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 06/05/2026 20:50:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 07/05/2026 14:05:00. 50 Economy ticket for £42 per person are available. Travel duration is 17h 15m
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| BlaBlaCar Bus | 17h 10m | 20:55 | Lyon | Perrache Train Station | 14:05 | Madrid | Sur Bus Station | Economy | £47 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 06/05/2026 20:55:00 to Sur Bus Station, Madrid (Spain) arriving at 07/05/2026 14:05:00. 50 Economy ticket for £47 per person are available. Travel duration is 17h 10m
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| Union Ivkoni | 22h 45m | 14:15 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 13:00 | Madrid | Mendez Alvaro Train Station | Basic | £56 |
A Bus from Union Ivkoni goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 06/05/2026 14:15:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 07/05/2026 13:00:00. 50 Basic ticket for £56 per person are available. Travel duration is 22h 45m
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| FlixBus | 16h 40m | 16:00 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 08:40 | Madrid | Sur Bus Station | Economy | £57 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 06/05/2026 16:00:00 to Sur Bus Station, Madrid (Spain) arriving at 07/05/2026 08:40:00. 50 Economy ticket for £57 per person are available. Travel duration is 16h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 17h 55m | 22:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 16:45 | Madrid | Mendez Alvaro Train Station | Economy | £34 |
A Bus from ALSA goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 07/05/2026 22:50:00 to Mendez Alvaro Train Station, Madrid (Spain) arriving at 08/05/2026 16:45:00. 50 Economy ticket for £34 per person are available. Travel duration is 17h 55m
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| FlixBus | 22h 35m | 09:20 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 07:55 | Madrid | Sur Bus Station | Economy | £86 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 07/05/2026 09:20:00 to Sur Bus Station, Madrid (Spain) arriving at 08/05/2026 07:55:00. 50 Economy ticket for £86 per person are available. Travel duration is 22h 35m
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| FlixBus | 17h 45m | 21:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 15:35 | Madrid | Sur Bus Station | Economy | £89 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 07/05/2026 21:50:00 to Sur Bus Station, Madrid (Spain) arriving at 08/05/2026 15:35:00. 50 Economy ticket for £89 per person are available. Travel duration is 17h 45m
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| FlixBus | 16h 40m | 16:00 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 08:40 | Madrid | Sur Bus Station | Economy | £97 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 07/05/2026 16:00:00 to Sur Bus Station, Madrid (Spain) arriving at 08/05/2026 08:40:00. 50 Economy ticket for £97 per person are available. Travel duration is 16h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ALSA | 17h 55m | 22:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 16:45 | Madrid | Sur Bus Station | Basic | £38 |
A Bus from ALSA goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 08/05/2026 22:50:00 to Sur Bus Station, Madrid (Spain) arriving at 09/05/2026 16:45:00. 50 Basic ticket for £38 per person are available. Travel duration is 17h 55m
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| ALSA | 17h 15m | 20:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 14:05 | Madrid | Sur Bus Station | Basic | £38 |
A Bus from ALSA goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 08/05/2026 20:50:00 to Sur Bus Station, Madrid (Spain) arriving at 09/05/2026 14:05:00. 50 Basic ticket for £38 per person are available. Travel duration is 17h 15m
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| BlaBlaCar Bus | 17h 10m | 20:55 | Lyon | Perrache Train Station | 14:05 | Madrid | Sur Bus Station | Economy | £39 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 08/05/2026 20:55:00 to Sur Bus Station, Madrid (Spain) arriving at 09/05/2026 14:05:00. 50 Economy ticket for £39 per person are available. Travel duration is 17h 10m
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| BlaBlaCar Bus | 17h 25m | 16:30 | Lyon | Perrache Train Station | 09:55 | Madrid | Sur Bus Station | Economy | £52 |
A Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 08/05/2026 16:30:00 to Sur Bus Station, Madrid (Spain) arriving at 09/05/2026 09:55:00. 50 Economy ticket for £52 per person are available. Travel duration is 17h 25m
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| FlixBus | 16h 40m | 16:00 | Lyon | Lyon Avenue Tony Garnier Coach Stop | 08:40 | Madrid | Sur Bus Station | Economy | £53 |
A Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 08/05/2026 16:00:00 to Sur Bus Station, Madrid (Spain) arriving at 09/05/2026 08:40:00. 50 Economy ticket for £53 per person are available. Travel duration is 16h 40m
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Best Price Offer: The price for the cheapest coach from Lyon to Madrid is £34 on 02/05/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Lyon and Madrid?
All facts for Lyon to Madrid bus at a glance
Compare all coach operators like FlixBus, ALSA and BlaBlaCar Bus that travel daily 12 times by bus from Lyon to Madrid in one click. Book your Lyon to Madrid bus ticket starting from £34!
| Cheapest Bus | £34 |
| Fastest Bus | 16h 40m |
| Earliest Coach | 05:20 |
| Latest Coach | 22:50 |
| Daily Bus Connections | 12 Ø |
| Distance | 912.1 km |
| Coach Companies | FlixBus, ALSA, BlaBlaCar Bus, Union Ivkoni and Internorte Transportes |
What are the cheapest coach tickets from Lyon to Madrid?
Every day, 12 buses from 5 coach companies leave Lyon for Madrid. Check the table below to find the cheapest prices for coach tickets for this route, starting from 02/05/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Lyon to Madrid
How to save money travelling from Lyon to Madrid
Book the ticket from Lyon to Madrid in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Lyon to Madrid, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Lyon to Madrid are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
Latest reviews for coach companies on the route Lyon - Madrid
All bus stations and stops in Lyon and Madrid
Here is a map with all coach stations in Lyon and Madrid. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Lyon to Madrid
FAQs for Lyon to Madrid bus
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How long does a bus to Madrid from Lyon take?
What time is the first bus from Lyon to Madrid?
What time is the last coach from Lyon to Madrid?
Which bus companies serve the Lyon Madrid route?
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What equipment is available for the Lyon Madrid bus route?
How does CheckMyBus find the best coach deals from Lyon to Madrid?
How does CheckMyBus technology work for trips from Lyon to Madrid?
Available seat classes which are offered on the bus route Lyon to Madrid
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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