Which bus from Frankfurt am Main to Lyon is the best?
Check the bus schedule for Frankfurt am Main to Lyon. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus, BlaBlaCar Bus or Sindbad. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 13h 5m | 15:30 | Frankfurt am Main | Central Station | 04:35 | Lyon | Perrache Bus Stop | Economy | £37 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 15/12/2025 15:30:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 04:35:00. 50 Economy ticket for £37 per person are available. Travel duration is 13h 5m
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| BlaBlaCar Bus | 16h 0m | 12:00 | Frankfurt am Main | Central Coach Station | 04:00 | Lyon | Perrache Train Station | Economy | £40 |
A Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 15/12/2025 12:00:00 to Perrache Train Station, Lyon (France) arriving at 16/12/2025 04:00:00. 50 Economy ticket for £40 per person are available. Travel duration is 16h 0m
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| FlixBus | 12h 20m | 08:15 | Frankfurt am Main | Central Station | 20:35 | Lyon | Perrache Bus Stop | Economy | £46 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 15/12/2025 08:15:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 20:35:00. 50 Economy ticket for £46 per person are available. Travel duration is 12h 20m
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| FlixBus | 11h 45m | 22:45 | Frankfurt am Main | Central Station | 10:30 | Lyon | Perrache Bus Stop | Economy | £46 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 15/12/2025 22:45:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 10:30:00. 50 Economy ticket for £46 per person are available. Travel duration is 11h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 12h 10m | 00:40 | Frankfurt am Main | Central Station | 12:50 | Lyon | Perrache Bus Stop | Economy | £35 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 16/12/2025 00:40:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 12:50:00. 50 Economy ticket for £35 per person are available. Travel duration is 12h 10m
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| FlixBus | 9h 40m | 19:05 | Frankfurt am Main | Central Station | 04:45 | Lyon | Perrache Bus Stop | Economy | £38 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 16/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 04:45:00. 50 Economy ticket for £38 per person are available. Travel duration is 9h 40m
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| FlixBus | 12h 20m | 08:15 | Frankfurt am Main | Central Station | 20:35 | Lyon | Perrache Bus Stop | Economy | £39 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 16/12/2025 08:15:00 to Perrache Bus Stop, Lyon (France) arriving at 16/12/2025 20:35:00. 50 Economy ticket for £39 per person are available. Travel duration is 12h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 11h 45m | 08:55 | Frankfurt am Main | Central Coach Station | 20:40 | Lyon | Perrache Train Station | Economy | £35 |
A Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 17/12/2025 08:55:00 to Perrache Train Station, Lyon (France) arriving at 17/12/2025 20:40:00. 50 Economy ticket for £35 per person are available. Travel duration is 11h 45m
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| FlixBus | 12h 20m | 08:15 | Frankfurt am Main | Central Station | 20:35 | Lyon | Perrache Bus Stop | Economy | £39 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 17/12/2025 08:15:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 20:35:00. 50 Economy ticket for £39 per person are available. Travel duration is 12h 20m
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| FlixBus | 9h 40m | 19:05 | Frankfurt am Main | Central Station | 04:45 | Lyon | Perrache Bus Stop | Economy | £39 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 17/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 04:45:00. 50 Economy ticket for £39 per person are available. Travel duration is 9h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 12h 10m | 00:40 | Frankfurt am Main | Central Station | 12:50 | Lyon | Perrache Bus Stop | Economy | £40 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 18/12/2025 00:40:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 12:50:00. 50 Economy ticket for £40 per person are available. Travel duration is 12h 10m
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| FlixBus | 12h 20m | 08:15 | Frankfurt am Main | Central Station | 20:35 | Lyon | Perrache Bus Stop | Economy | £42 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 18/12/2025 08:15:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 20:35:00. 50 Economy ticket for £42 per person are available. Travel duration is 12h 20m
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| BlaBlaCar Bus | 10h 35m | 18:30 | Frankfurt am Main | Central Coach Station | 05:05 | Lyon | Perrache Train Station | Economy | £44 |
A Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 18/12/2025 18:30:00 to Perrache Train Station, Lyon (France) arriving at 19/12/2025 05:05:00. 50 Economy ticket for £44 per person are available. Travel duration is 10h 35m
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| FlixBus | 9h 40m | 19:05 | Frankfurt am Main | Central Station | 04:45 | Lyon | Perrache Bus Stop | Economy | £46 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 18/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 04:45:00. 50 Economy ticket for £46 per person are available. Travel duration is 9h 40m
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| BlaBlaCar Bus | 14h 5m | 12:00 | Frankfurt am Main | Central Coach Station | 02:05 | Lyon | Perrache Train Station | Economy | £61 |
A Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 18/12/2025 12:00:00 to Perrache Train Station, Lyon (France) arriving at 19/12/2025 02:05:00. 50 Economy ticket for £61 per person are available. Travel duration is 14h 5m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 12h 20m | 08:15 | Frankfurt am Main | Central Station | 20:35 | Lyon | Perrache Bus Stop | Economy | £52 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 19/12/2025 08:15:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 20:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 12h 20m
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| BlaBlaCar Bus | 11h 45m | 08:55 | Frankfurt am Main | Central Coach Station | 20:40 | Lyon | Perrache Train Station | Economy | £53 |
A Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 19/12/2025 08:55:00 to Perrache Train Station, Lyon (France) arriving at 19/12/2025 20:40:00. 50 Economy ticket for £53 per person are available. Travel duration is 11h 45m
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| FlixBus | 12h 10m | 00:40 | Frankfurt am Main | Central Station | 12:50 | Lyon | Perrache Bus Stop | Economy | £65 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 19/12/2025 00:40:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 12:50:00. 50 Economy ticket for £65 per person are available. Travel duration is 12h 10m
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| BlaBlaCar Bus | 14h 5m | 12:00 | Frankfurt am Main | Central Coach Station | 02:05 | Lyon | Perrache Train Station | Economy | £66 |
A Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 19/12/2025 12:00:00 to Perrache Train Station, Lyon (France) arriving at 20/12/2025 02:05:00. 50 Economy ticket for £66 per person are available. Travel duration is 14h 5m
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| FlixBus | 13h 5m | 15:30 | Frankfurt am Main | Central Station | 04:35 | Lyon | Perrache Bus Stop | Economy | £67 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 19/12/2025 15:30:00 to Perrache Bus Stop, Lyon (France) arriving at 20/12/2025 04:35:00. 50 Economy ticket for £67 per person are available. Travel duration is 13h 5m
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FlixBus17h 5m019:45Frankfurt am MainCentral Station23:30StrasbourgPlace de l'Etoile0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 16/12/2025 19:45:00 to Place de l'Etoile, Strasbourg (France) arriving at 16/12/2025 23:30:00. 50 Economy ticket for £13 per person are available. Travel duration is 3h 45m
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FlixBus7h 10m005:40StrasbourgPlace de l'Etoile12:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Place de l'Etoile, Strasbourg (France) at 17/12/2025 05:40:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 12:50:00. 50 Economy ticket for £29 per person are available. Travel duration is 7h 10m
Waiting Time 6h 10m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 11h 45m | 22:45 | Frankfurt am Main | Central Station | 10:30 | Lyon | Perrache Bus Stop | Economy | £63 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 20/12/2025 22:45:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 10:30:00. 50 Economy ticket for £63 per person are available. Travel duration is 11h 45m
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| FlixBus | 12h 10m | 00:40 | Frankfurt am Main | Central Station | 12:50 | Lyon | Perrache Bus Stop | Economy | £64 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 20/12/2025 00:40:00 to Perrache Bus Stop, Lyon (France) arriving at 20/12/2025 12:50:00. 50 Economy ticket for £64 per person are available. Travel duration is 12h 10m
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| FlixBus | 12h 20m | 08:15 | Frankfurt am Main | Central Station | 20:35 | Lyon | Perrache Bus Stop | Economy | £69 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 20/12/2025 08:15:00 to Perrache Bus Stop, Lyon (France) arriving at 20/12/2025 20:35:00. 50 Economy ticket for £69 per person are available. Travel duration is 12h 20m
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| FlixBus | 9h 40m | 19:05 | Frankfurt am Main | Central Station | 04:45 | Lyon | Perrache Bus Stop | Economy | £72 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 20/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 04:45:00. 50 Economy ticket for £72 per person are available. Travel duration is 9h 40m
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| FlixBus | 13h 5m | 15:30 | Frankfurt am Main | Central Station | 04:35 | Lyon | Perrache Bus Stop | Economy | £73 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 20/12/2025 15:30:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 04:35:00. 50 Economy ticket for £73 per person are available. Travel duration is 13h 5m
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FlixBus12h 30m019:45Frankfurt am MainCentral Station23:30StrasbourgPlace de l'Etoile0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 16/12/2025 19:45:00 to Place de l'Etoile, Strasbourg (France) arriving at 16/12/2025 23:30:00. 50 Economy ticket for £13 per person are available. Travel duration is 3h 45m
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FlixBus6h 55m001:20StrasbourgPlace de l'Etoile08:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Place de l'Etoile, Strasbourg (France) at 17/12/2025 01:20:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 08:15:00. 50 Economy ticket for £30 per person are available. Travel duration is 6h 55m
Waiting Time 1h 50m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sindbad | 10h 10m | 07:35 | Frankfurt am Main | Central Coach Station | 17:45 | Lyon | Perrache Bus Stop | Basic | £53 |
A Bus from Sindbad goes from Central Coach Station, Frankfurt am Main (Germany) at 21/12/2025 07:35:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 17:45:00. 50 Basic ticket for £53 per person are available. Travel duration is 10h 10m
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| BlaBlaCar Bus | 10h 35m | 18:30 | Frankfurt am Main | Central Coach Station | 05:05 | Lyon | Perrache Train Station | Economy | £57 |
A Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 21/12/2025 18:30:00 to Perrache Train Station, Lyon (France) arriving at 22/12/2025 05:05:00. 50 Economy ticket for £57 per person are available. Travel duration is 10h 35m
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| FlixBus | 9h 40m | 19:05 | Frankfurt am Main | Central Station | 04:45 | Lyon | Perrache Bus Stop | Economy | £60 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 21/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 04:45:00. 50 Economy ticket for £60 per person are available. Travel duration is 9h 40m
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| FlixBus | 12h 20m | 08:15 | Frankfurt am Main | Central Station | 20:35 | Lyon | Perrache Bus Stop | Economy | £61 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 21/12/2025 08:15:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 20:35:00. 50 Economy ticket for £61 per person are available. Travel duration is 12h 20m
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| BlaBlaCar Bus | 14h 5m | 12:00 | Frankfurt am Main | Central Coach Station | 02:05 | Lyon | Perrache Train Station | Economy | £92 |
A Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 21/12/2025 12:00:00 to Perrache Train Station, Lyon (France) arriving at 22/12/2025 02:05:00. 50 Economy ticket for £92 per person are available. Travel duration is 14h 5m
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FlixBus12h 30m019:45Frankfurt am MainCentral Station23:30StrasbourgPlace de l'Etoile0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 16/12/2025 19:45:00 to Place de l'Etoile, Strasbourg (France) arriving at 16/12/2025 23:30:00. 50 Economy ticket for £13 per person are available. Travel duration is 3h 45m
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FlixBus6h 55m001:20StrasbourgPlace de l'Etoile08:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Place de l'Etoile, Strasbourg (France) at 17/12/2025 01:20:00 to Perrache Bus Stop, Lyon (France) arriving at 17/12/2025 08:15:00. 50 Economy ticket for £30 per person are available. Travel duration is 6h 55m
Waiting Time 1h 50m -
Best Price Offer: The price for the cheapest coach from Frankfurt am Main to Lyon is £27 on 08/01/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Frankfurt am Main and Lyon?
All facts for Frankfurt am Main to Lyon bus at a glance
Compare all coach operators like FlixBus, BlaBlaCar Bus and Sindbad that travel daily 5 times by bus from Frankfurt am Main to Lyon in one click. Book your Frankfurt am Main to Lyon bus ticket starting from £27!
| Cheapest Bus | £27 |
| Fastest Bus | 9h 40m |
| Earliest Coach | 08:15 |
| Latest Coach | 22:45 |
| Daily Bus Connections | 5 Ø |
| Distance | 562.3 km |
| Coach Companies | FlixBus, BlaBlaCar Bus and Sindbad |
What are the cheapest coach tickets from Frankfurt am Main to Lyon?
Every day, 5 buses from 3 coach companies leave Frankfurt am Main for Lyon. Check the table below to find the cheapest prices for coach tickets for this route, starting from 15/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Frankfurt am Main to Lyon
How to save money travelling from Frankfurt am Main to Lyon
Book the ticket from Frankfurt am Main to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Frankfurt am Main to Lyon, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Frankfurt am Main to Lyon are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Frankfurt am Main and Lyon
Here is a map with all coach stations in Frankfurt am Main and Lyon. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Frankfurt am Main to Lyon
FAQs for Frankfurt am Main to Lyon bus
How much does a Frankfurt am Main Lyon coach trip cost?
How much could I save by comparing buses from Frankfurt am Main to Lyon?
How many connections are available for the Frankfurt am Main Lyon route on average every day?
How long does a bus to Lyon from Frankfurt am Main take?
What time is the first bus from Frankfurt am Main to Lyon?
What time is the last coach from Frankfurt am Main to Lyon?
Which bus companies serve the Frankfurt am Main Lyon route?
Is there a direct bus between Frankfurt am Main and Lyon?
What can I take with me on the bus to Lyon from Frankfurt am Main?
What equipment is available for the Frankfurt am Main Lyon bus route?
How does CheckMyBus find the best coach deals from Frankfurt am Main to Lyon?
How does CheckMyBus technology work for trips from Frankfurt am Main to Lyon?
Available seat classes which are offered on the bus route Frankfurt am Main to Lyon
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Frankfurt am Main and to Lyon
- Bus Routes to Frankfurt am Main
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- Coach Brcko to Frankfurt am Main
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- Bus from Dnipro to Frankfurt am Main
- Bus Geneva to Frankfurt am Main
- Bus to Frankfurt am Main from Istanbul
- Coach from Koblenz to Frankfurt am Main
- Coach Lecce to Frankfurt am Main
- London to Frankfurt am Main bus
- Coach Minsk to Frankfurt am Main
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- Coach to Frankfurt am Main from Rijeka
- Bus Rothenburg ob der Tauber to Frankfurt am Main
- Warsaw to Frankfurt am Main coach
- Bus Zurich to Frankfurt am Main
- Bus Routes to Lyon
- Bus to Lyon from Aime-la-Plagne
- Bus from Bari to Lyon
- Brest to Lyon coach
- Bus to Lyon from Clermont-Ferrand
- Coach to Lyon from Geneva
- Coach Genoa to Lyon
- Bus to Lyon from La Rochelle
- Bus to Lyon from Lisbon
- Coach London to Lyon
- Coach Manchester to Lyon
- Bus from Metz to Lyon
- Coach to Lyon from Montpellier
- Coach to Lyon from Moutiers
- Coaches Nancy to Lyon
- Bus to Lyon from Nantes
- Coach to Lyon from Nottingham
- Coach to Lyon from Paris
- Porto to Lyon bus
- Taunton to Lyon coach
- Coach Venice to Lyon

