Which bus from Frankfurt am Main to Lyon is the best?
Check the bus schedule for Frankfurt am Main to Lyon. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or BlaBlaCar Bus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 10h 35m | 18:30 | Frankfurt am Main | Central Coach Station | 05:05 | Lyon | Perrache Train Station | Economy | £28 |
A Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 05/12/2025 18:30:00 to Perrache Train Station, Lyon (France) arriving at 06/12/2025 05:05:00. 50 Economy ticket for £28 per person are available. Travel duration is 10h 35m
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| FlixBus | 11h 45m | 22:45 | Frankfurt am Main | Central Station | 10:30 | Lyon | Perrache Bus Stop | Economy | £39 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 05/12/2025 22:45:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 10:30:00. 50 Economy ticket for £39 per person are available. Travel duration is 11h 45m
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| BlaBlaCar Bus | 11h 45m | 08:55 | Frankfurt am Main | Central Coach Station | 20:40 | Lyon | Perrache Train Station | Economy | £39 |
A Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 05/12/2025 08:55:00 to Perrache Train Station, Lyon (France) arriving at 05/12/2025 20:40:00. 50 Economy ticket for £39 per person are available. Travel duration is 11h 45m
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| FlixBus | 12h 20m | 08:15 | Frankfurt am Main | Central Station | 20:35 | Lyon | Perrache Bus Stop | Economy | £40 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 05/12/2025 08:15:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 20:35:00. 50 Economy ticket for £40 per person are available. Travel duration is 12h 20m
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| FlixBus | 12h 10m | 00:40 | Frankfurt am Main | Central Station | 12:50 | Lyon | Perrache Bus Stop | Economy | £50 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 05/12/2025 00:40:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 12:50:00. 50 Economy ticket for £50 per person are available. Travel duration is 12h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 9h 40m | 19:05 | Frankfurt am Main | Central Station | 04:45 | Lyon | Perrache Bus Stop | Economy | £36 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 06/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 04:45:00. 50 Economy ticket for £36 per person are available. Travel duration is 9h 40m
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| FlixBus | 12h 10m | 00:40 | Frankfurt am Main | Central Station | 12:50 | Lyon | Perrache Bus Stop | Economy | £37 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 06/12/2025 00:40:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 12:50:00. 50 Economy ticket for £37 per person are available. Travel duration is 12h 10m
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| FlixBus | 11h 45m | 22:45 | Frankfurt am Main | Central Station | 10:30 | Lyon | Perrache Bus Stop | Economy | £37 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 06/12/2025 22:45:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 10:30:00. 50 Economy ticket for £37 per person are available. Travel duration is 11h 45m
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| FlixBus | 12h 20m | 08:15 | Frankfurt am Main | Central Station | 20:35 | Lyon | Perrache Bus Stop | Economy | £38 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 06/12/2025 08:15:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 20:35:00. 50 Economy ticket for £38 per person are available. Travel duration is 12h 20m
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| FlixBus | 13h 5m | 15:30 | Frankfurt am Main | Central Station | 04:35 | Lyon | Perrache Bus Stop | Economy | £50 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 06/12/2025 15:30:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 04:35:00. 50 Economy ticket for £50 per person are available. Travel duration is 13h 5m
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FlixBus12h 15m020:00Frankfurt am MainCentral Station22:00KarlsruheCentral Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 06/12/2025 20:00:00 to Central Station, Karlsruhe (Germany) arriving at 06/12/2025 22:00:00. 50 Economy ticket for £7 per person are available. Travel duration is 2h 0m
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FlixBus8h 20m023:55KarlsruheCentral Station08:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Central Station, Karlsruhe (Germany) at 06/12/2025 23:55:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 08:15:00. 50 Economy ticket for £24 per person are available. Travel duration is 8h 20m
Waiting Time 1h 55m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 10h 35m | 18:30 | Frankfurt am Main | Central Coach Station | 05:05 | Lyon | Perrache Train Station | Economy | £26 |
A Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 07/12/2025 18:30:00 to Perrache Train Station, Lyon (France) arriving at 08/12/2025 05:05:00. 50 Economy ticket for £26 per person are available. Travel duration is 10h 35m
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| FlixBus | 9h 40m | 19:05 | Frankfurt am Main | Central Station | 04:45 | Lyon | Perrache Bus Stop | Economy | £38 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 07/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 04:45:00. 50 Economy ticket for £38 per person are available. Travel duration is 9h 40m
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| FlixBus | 12h 10m | 00:40 | Frankfurt am Main | Central Station | 12:50 | Lyon | Perrache Bus Stop | Economy | £42 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 07/12/2025 00:40:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 12:50:00. 50 Economy ticket for £42 per person are available. Travel duration is 12h 10m
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| FlixBus | 13h 5m | 15:30 | Frankfurt am Main | Central Station | 04:35 | Lyon | Perrache Bus Stop | Economy | £44 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 07/12/2025 15:30:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 04:35:00. 50 Economy ticket for £44 per person are available. Travel duration is 13h 5m
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| BlaBlaCar Bus | 11h 45m | 08:55 | Frankfurt am Main | Central Coach Station | 20:40 | Lyon | Perrache Train Station | Economy | £57 |
A Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 07/12/2025 08:55:00 to Perrache Train Station, Lyon (France) arriving at 07/12/2025 20:40:00. 50 Economy ticket for £57 per person are available. Travel duration is 11h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 9h 40m | 19:05 | Frankfurt am Main | Central Station | 04:45 | Lyon | Perrache Bus Stop | Economy | £31 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 08/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 04:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 9h 40m
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| FlixBus | 11h 45m | 22:45 | Frankfurt am Main | Central Station | 10:30 | Lyon | Perrache Bus Stop | Economy | £32 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 08/12/2025 22:45:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 10:30:00. 50 Economy ticket for £32 per person are available. Travel duration is 11h 45m
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| FlixBus | 13h 5m | 15:30 | Frankfurt am Main | Central Station | 04:35 | Lyon | Perrache Bus Stop | Economy | £33 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 08/12/2025 15:30:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 04:35:00. 50 Economy ticket for £33 per person are available. Travel duration is 13h 5m
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| FlixBus | 12h 10m | 00:40 | Frankfurt am Main | Central Station | 12:50 | Lyon | Perrache Bus Stop | Economy | £34 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 08/12/2025 00:40:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 12:50:00. 50 Economy ticket for £34 per person are available. Travel duration is 12h 10m
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| FlixBus | 12h 20m | 08:15 | Frankfurt am Main | Central Station | 20:35 | Lyon | Perrache Bus Stop | Economy | £37 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 08/12/2025 08:15:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 20:35:00. 50 Economy ticket for £37 per person are available. Travel duration is 12h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 9h 40m | 19:05 | Frankfurt am Main | Central Station | 04:45 | Lyon | Perrache Bus Stop | Economy | £29 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 09/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 04:45:00. 50 Economy ticket for £29 per person are available. Travel duration is 9h 40m
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| FlixBus | 12h 20m | 08:15 | Frankfurt am Main | Central Station | 20:35 | Lyon | Perrache Bus Stop | Economy | £30 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 09/12/2025 08:15:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 20:35:00. 50 Economy ticket for £30 per person are available. Travel duration is 12h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 12h 20m | 08:15 | Frankfurt am Main | Central Station | 20:35 | Lyon | Perrache Bus Stop | Economy | £31 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/12/2025 08:15:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 20:35:00. 50 Economy ticket for £31 per person are available. Travel duration is 12h 20m
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| FlixBus | 9h 40m | 19:05 | Frankfurt am Main | Central Station | 04:45 | Lyon | Perrache Bus Stop | Economy | £31 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 10/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 04:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 9h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 10h 35m | 18:30 | Frankfurt am Main | Central Coach Station | 05:05 | Lyon | Perrache Train Station | Economy | £26 |
A Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 11/12/2025 18:30:00 to Perrache Train Station, Lyon (France) arriving at 12/12/2025 05:05:00. 50 Economy ticket for £26 per person are available. Travel duration is 10h 35m
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| FlixBus | 9h 40m | 19:05 | Frankfurt am Main | Central Station | 04:45 | Lyon | Perrache Bus Stop | Economy | £31 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 11/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 04:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 9h 40m
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| FlixBus | 11h 45m | 22:45 | Frankfurt am Main | Central Station | 10:30 | Lyon | Perrache Bus Stop | Economy | £32 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 11/12/2025 22:45:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 10:30:00. 50 Economy ticket for £32 per person are available. Travel duration is 11h 45m
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| FlixBus | 12h 10m | 00:40 | Frankfurt am Main | Central Station | 12:50 | Lyon | Perrache Bus Stop | Economy | £33 |
A Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 11/12/2025 00:40:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 12:50:00. 50 Economy ticket for £33 per person are available. Travel duration is 12h 10m
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BlaBlaCar Bus11h 45m008:55Frankfurt am MainCentral Coach Station11:10KarlsruheCentral Station0EconomyA Bus from BlaBlaCar Bus goes from Central Coach Station, Frankfurt am Main (Germany) at 12/12/2025 08:55:00 to Central Station, Karlsruhe (Germany) arriving at 12/12/2025 11:10:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 15m
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BlaBlaCar Bus9h 25m011:15KarlsruheCentral Station20:40LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Central Station, Karlsruhe (Germany) at 12/12/2025 11:15:00 to Perrache Train Station, Lyon (France) arriving at 12/12/2025 20:40:00. 50 Economy ticket for £17 per person are available. Travel duration is 9h 25m
Waiting Time 0h 5m -
Best Price Offer: The price for the cheapest coach from Frankfurt am Main to Lyon is £26 on 07/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Frankfurt am Main and Lyon?
All facts for Frankfurt am Main to Lyon bus at a glance
Compare all coach operators like FlixBus and BlaBlaCar Bus that travel daily 4 times by bus from Frankfurt am Main to Lyon in one click. Book your Frankfurt am Main to Lyon bus ticket starting from £26!
| Cheapest Bus | £26 |
| Fastest Bus | 9h 40m |
| Earliest Coach | 00:40 |
| Latest Coach | 22:45 |
| Daily Bus Connections | 4 Ø |
| Distance | 562.3 km |
| Coach Companies | FlixBus and BlaBlaCar Bus |
What are the cheapest coach tickets from Frankfurt am Main to Lyon?
Every day, 4 buses from 2 coach companies leave Frankfurt am Main for Lyon. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Frankfurt am Main to Lyon
How to save money travelling from Frankfurt am Main to Lyon
Book the ticket from Frankfurt am Main to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Frankfurt am Main to Lyon, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Frankfurt am Main to Lyon are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Frankfurt am Main and Lyon
Here is a map with all coach stations in Frankfurt am Main and Lyon. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Frankfurt am Main to Lyon
FAQs for Frankfurt am Main to Lyon bus
How much does a Frankfurt am Main Lyon coach trip cost?
How much could I save by comparing buses from Frankfurt am Main to Lyon?
How many connections are available for the Frankfurt am Main Lyon route on average every day?
How long does a bus to Lyon from Frankfurt am Main take?
What time is the first bus from Frankfurt am Main to Lyon?
What time is the last coach from Frankfurt am Main to Lyon?
Which bus companies serve the Frankfurt am Main Lyon route?
Is there a direct bus between Frankfurt am Main and Lyon?
What can I take with me on the bus to Lyon from Frankfurt am Main?
What equipment is available for the Frankfurt am Main Lyon bus route?
Available seat classes which are offered on the bus route Frankfurt am Main to Lyon
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Frankfurt am Main and to Lyon
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- Bus Routes to Lyon
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