Bus tickets Santander to Madrid from £2

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Compare all timetables for the bus from Santander to Madrid

Here is a selection of the cheapest bus trips from the schedule from Santander to Madrid from various bus operators like ALSA or FlixBus for the next days.

today
£32
tomorrow
£32
Wednesday
£33
Thursday
£32
Friday
£32
Saturday
£32
Sunday
£32

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 6h 15m 10:30 Santander Coach Station 16:45 Madrid Avenida de América Coach Station  Economy £32
ALSA 5h 30m 17:30 Santander Coach Station 23:00 Madrid Avenida de América Coach Station  Economy £32
ALSA 6h 45m 16:00 Santander Coach Station 22:45 Madrid Intercambiador de Moncloa  Economy £32
FlixBus 21h 45m 09:25 Santander Coach Station 07:10 Madrid Sur Bus Station  Economy £94
FlixBus 18h 30m 18:50 Santander Coach Station 13:20 Madrid Sur Bus Station  Economy £110

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 6h 45m 16:00 Santander Coach Station 22:45 Madrid Intercambiador de Moncloa  Economy £32
ALSA 5h 30m 17:30 Santander Coach Station 23:00 Madrid Avenida de América Coach Station  Economy £34
ALSA 5h 50m 08:00 Santander Coach Station 13:50 Madrid Avenida de América Coach Station  Economy £36
FlixBus 18h 30m 18:50 Santander Coach Station 13:20 Madrid Sur Bus Station  Economy £85
FlixBus 21h 45m 09:25 Santander Coach Station 07:10 Madrid Sur Bus Station  Economy £117

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 6h 15m 10:30 Santander Coach Station 16:45 Madrid Avenida de América Coach Station  Economy £33
ALSA 6h 45m 16:00 Santander Coach Station 22:45 Madrid Intercambiador de Moncloa  Economy £33
ALSA 5h 30m 17:30 Santander Coach Station 23:00 Madrid Avenida de América Coach Station  Economy £35
FlixBus 18h 30m 18:50 Santander Coach Station 13:20 Madrid Sur Bus Station  Economy £62
FlixBus 21h 45m 09:25 Santander Coach Station 07:10 Madrid Sur Bus Station  Economy £76

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 6h 15m 10:30 Santander Coach Station 16:45 Madrid Avenida de América Coach Station  Economy £32
ALSA 6h 45m 16:00 Santander Coach Station 22:45 Madrid Intercambiador de Moncloa  Economy £32
ALSA 5h 45m 00:45 Santander Coach Station 06:30 Madrid Avenida de Aragon  Economy £33
FlixBus 18h 30m 18:50 Santander Coach Station 13:20 Madrid Sur Bus Station  Economy £81
FlixBus 21h 45m 09:25 Santander Coach Station 07:10 Madrid Sur Bus Station  Economy £119

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 6h 45m 16:00 Santander Coach Station 22:45 Madrid Intercambiador de Moncloa  Economy £32
ALSA 5h 30m 17:30 Santander Coach Station 23:00 Madrid Avenida de América Coach Station  Economy £34
ALSA 5h 45m 00:45 Santander Coach Station 06:30 Madrid Avenida de América Coach Station  Economy £47
FlixBus 18h 30m 18:50 Santander Coach Station 13:20 Madrid Sur Bus Station  Economy £96
FlixBus 21h 45m 09:25 Santander Coach Station 07:10 Madrid Sur Bus Station  Economy £141

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 6h 45m 16:00 Santander Coach Station 22:45 Madrid Intercambiador de Moncloa  Economy £32
ALSA 5h 30m 17:30 Santander Coach Station 23:00 Madrid Avenida de América Coach Station  Economy £34
ALSA 6h 15m 10:30 Santander Coach Station 16:45 Madrid Avenida de América Coach Station  Economy £36
FlixBus 18h 30m 18:50 Santander Coach Station 13:20 Madrid Sur Bus Station  Economy £73
FlixBus 21h 45m 09:25 Santander Coach Station 07:10 Madrid Sur Bus Station  Economy £116

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
ALSA 6h 45m 16:00 Santander Coach Station 22:45 Madrid Intercambiador de Moncloa  Economy £32
ALSA 5h 30m 01:00 Santander Coach Station 06:30 Madrid Avenida de América Coach Station  Economy £36
ALSA 5h 30m 17:30 Santander Coach Station 23:00 Madrid Avenida de Aragon  Economy £37
FlixBus 18h 30m 18:50 Santander Coach Station 13:20 Madrid Sur Bus Station  Economy £93
FlixBus 21h 45m 09:25 Santander Coach Station 07:10 Madrid Sur Bus Station  Economy £122

Best Price Offer: The price for the cheapest coach from Santander to Madrid is £2 on 14/09/2026. Flexible travellers save on ticket prices.


Frequency of bus connections between Santander and Madrid

See here how frequent the connections between Santander and Madrid are, during different times and days of the week.
Wednesday is the busiest day, with more than 35 daily coaches from Santander to Madrid. Saturday has instead the fewest connections, with only 13 daily coaches between Santander and Madrid.
The busiest time of the day is the Afternoon, with 80 coaches from Santander to Madrid, while Evening sees the fewest connections between Santander and Madrid, with 7 offers.

Facts about coaches from Santander to Madrid

Compare all providers like ALSA and FlixBus that travel 25 times every day by bus from Santander to Madrid in one click! Book your bus ticket from Santander to Madrid starting from £2!

Cheapest Bus £2
Fastest Bus 5h 15m
Earliest Coach 06:00
Latest Coach 18:50
Daily Bus Connections 25 Ø
Distance 338.8 km
Coach Companies ALSA and FlixBus

Cheapest coach connections from Santander to Madrid

Every day, 25 buses from 2 coach companies leave Santander for Madrid: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 14/09/2026 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 14/09
£2
Tuesday 15/09
£32
Wednesday 16/09
£2
Thursday 17/09
£81
Friday 18/09
£2
Saturday 19/09
£2
Sunday 20/09
£2
Monday 21/09
£2
Tuesday 22/09
£2
Wednesday 23/09
£32
Thursday 24/09
£2
Friday 25/09
£34
Saturday 26/09
£32
Sunday 27/09
£32
Monday 28/09
£2
Tuesday 29/09
£34
Wednesday 30/09
£32
Thursday 01/10
£2
Friday 02/10
£35
Saturday 03/10
£32
Sunday 04/10
£32
Monday 05/10
£2
Tuesday 06/10
£3
Wednesday 07/10
£35
Thursday 08/10
£2
Friday 09/10
£32
Saturday 10/10
£32
Sunday 11/10

The cheapest time to travel from Santander to Madrid

See here on which day and which time of the day you can find the cheapest bus ticket from Santander to Madrid, for the next 30 days.
With a price starting from £2, Monday is the cheapest day for a coach from Santander to Madrid. Monday instead is the most expensive day with prices starting from £2.
Night is the cheapest day time for bus tickets from Santander to Madrid, with £2. Evening is the most expensive time of the day with prices starting from £62.

How to save money travelling from Santander to Madrid

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santander to Madrid in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santander to Madrid, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Santander to Madrid are also emptier.

All bus stations and stops in Santander and Madrid

The map below shows you where to find all the bus stations in Santander and Madrid.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Santander to Madrid? Compare all modes of transports from Santander to Madrid.

Service and Comfort on the bus from Santander to Madrid

Want to know which seat classes are available on the coaches from Santander to Madrid? Or which bus companies serve the route Santander to Madrid? Below you will find answers to your questions.

FAQs about the Santander to Madrid bus

How much does a Santander - Madrid coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Santander - Madrid bus trip is available from £2 and takes 6h 15m. Compare offers and save money!

How much could I save by comparing buses from Santander to Madrid?

The connection Santander to Madrid is offered by 2 companies with ticket prices ranging from £2 to £141. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Santander - Madrid route on average every day?

Each day, the bus route from Santander to Madrid is offered by roughly 25 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Madrid from Santander take?

The quickest coach from Santander to Madrid is provided by ALSA and takes 5h 15m. Coach tickets for this connection cost £45. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Santander to Madrid?

The earliest bus to Madrid departs from Santander at 06:00. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Santander to Madrid?

The latest bus to Madrid departs from Santander at 18:50. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Santander - Madrid route?

Passengers looking to travel from Santander to Madrid can travel with ALSA and FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Santander and Madrid?

You can check all the direct connections between Santander and Madrid by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: ALSA and FlixBus.

What can I take with me on the bus to Madrid from Santander?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Santander Madrid bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Santander Madrid bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santander to Madrid on your planned travel date.

How does CheckMyBus find the best bus deals from Santander to Madrid?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 25 daily trips between Santander and Madrid. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santander to Madrid?

Prices and availability for 25 trips between Santander and Madrid change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santander to Madrid

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Santander and to Madrid

Here’s an overview of the most popular bus routes to Santander and to Madrid. Simply click on the connection of your choice, and you will find all the details about your bus route!
Coach from Comillas to Santander Coach from Comillas to Santander
Coach to Santander from Avilés Coach to Santander from Avilés
Bus Covadonga to Santander Bus Covadonga to Santander
Bus to Santander from Requejada Bus to Santander from Requejada
Écija to Madrid bus Écija to Madrid bus
Bus from Zurich to Madrid Bus from Zurich to Madrid
Coach Los Ángeles de San Rafael to Madrid Coach Los Ángeles de San Rafael to Madrid
Buses Calp to Madrid Buses Calp to Madrid
Popular Airport Transfers to Santander and to Madrid
CheckMyBus › Coaches in Spain › Coach to Santander › Coach to Madrid

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