Bus tickets La Serena to Antofagasta from £16

Compare all the coach companies and find the best price with CheckMyBus
Compare & Save Millions of buses in one click. Save up to 70%!
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from La Serena to Antofagasta

Here is a selection of the cheapest bus trips from the schedule from La Serena to Antofagasta from various bus operators like Pullman San Andres, Pullman Bus or Pluss Chile for the next days.

today
£24
tomorrow
£22
Wednesday
£23
Thursday
£23
Friday
£21
Saturday
£24
Sunday
£22

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 11h 35m 14:00 La Serena Central Coach Station 01:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £24
Pullman San Andres 12h 0m 06:00 La Serena Central Coach Station 18:00 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £26
Cormar Bus 10h 30m 16:30 La Serena Central Coach Station 03:00 Antofagasta Carlos Oviedo Cavada Bus Station  First Class £29
Pluss Chile 11h 20m 14:20 La Serena Central Coach Station 01:40 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £30
Nueva Andimar Vip 11h 35m 20:15 La Serena Central Coach Station 07:50 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £30

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 11h 30m 18:40 La Serena Central Coach Station 06:10 Antofagasta Camus Coach Station  Premium Economy £22
FlixBus 11h 35m 14:00 La Serena Central Coach Station 01:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £24
Pullman San Andres 12h 10m 22:00 La Serena Central Coach Station 10:10 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £26
Cikbus Elité 11h 45m 05:15 La Serena Central Coach Station 17:00 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Pluss Chile 11h 35m 05:50 La Serena Central Coach Station 17:25 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £30

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 11h 35m 17:10 La Serena Central Coach Station 04:45 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £23
Pullman San Andres 12h 10m 20:30 La Serena Central Coach Station 08:40 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £26
Cormar Bus 11h 10m 15:30 La Serena Central Coach Station 02:40 Antofagasta Camus Coach Station  First Class £27
Cikbus Elité 11h 45m 05:15 La Serena Central Coach Station 17:00 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Pullman Bus 13h 5m 03:30 La Serena El Sto, 1060 16:35 Antofagasta Camus Coach Station  First Class £34
  • Did you know that if you travel from La Serena to Antofagasta via Ovalle, you can save more than £3? You can find the corresponding connections below.
    • FlixBus
      15h 50m
      0
      15:00
      La Serena
      Central Coach Station
      16:45
      Ovalle
      Coach Station
      0
      FlixBus
      Economy
      £2
    • Waiting Time 1h 0m
    • FlixBus
      13h 5m
      0
      17:45
      Ovalle
      Coach Station
      06:50
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      FlixBus
      Economy
      £18
    Travel time is 4h 40m longer, but you will save £3

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 11h 35m 14:00 La Serena Central Coach Station 01:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £23
FlixBus 11h 35m 19:15 La Serena Central Coach Station 06:50 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £23
Pullman San Andres 12h 10m 22:00 La Serena Central Coach Station 10:10 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £26
Cormar Bus 10h 30m 19:45 La Serena Central Coach Station 06:15 Antofagasta Carlos Oviedo Cavada Bus Station  First Class £28
Cormar Bus 11h 0m 01:35 La Serena Central Coach Station 12:35 Antofagasta Camus Coach Station  First Class £28

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 11h 30m 18:40 La Serena Central Coach Station 06:10 Antofagasta Camus Coach Station  Premium Economy £21
Nueva Andimar Vip 11h 35m 14:00 La Serena Central Coach Station 01:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £23
FlixBus 11h 35m 17:10 La Serena Central Coach Station 04:45 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £24
Pullman San Andres 12h 10m 13:30 La Serena Central Coach Station 01:40 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £26
Pullman Bus 13h 5m 03:30 La Serena El Sto, 1060 16:35 Antofagasta Camus Coach Station  First Class £34

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 11h 35m 14:00 La Serena Central Coach Station 01:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £24
FlixBus 11h 35m 17:10 La Serena Central Coach Station 04:45 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £24
Pullman San Andres 12h 10m 22:00 La Serena Central Coach Station 10:10 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £26
Cormar Bus 11h 0m 01:35 La Serena Central Coach Station 12:35 Antofagasta Camus Coach Station  First Class £28
Cikbus Elité 11h 45m 05:15 La Serena Central Coach Station 17:00 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
  • Did you know that if you travel from La Serena to Antofagasta via Ovalle, you can save more than £4? You can find the corresponding connections below.
    • FlixBus
      15h 50m
      0
      15:00
      La Serena
      Central Coach Station
      16:45
      Ovalle
      Coach Station
      0
      FlixBus
      Economy
      £2
    • Waiting Time 1h 0m
    • FlixBus
      13h 5m
      0
      17:45
      Ovalle
      Coach Station
      06:50
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      FlixBus
      Economy
      £18
    Travel time is 4h 50m longer, but you will save £4

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 11h 30m 18:40 La Serena Central Coach Station 06:10 Antofagasta Camus Coach Station  Premium Economy £22
Nueva Andimar Vip 11h 35m 19:15 La Serena Central Coach Station 06:50 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £23
FlixBus 11h 35m 14:00 La Serena Central Coach Station 01:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £24
Pullman San Andres 12h 10m 22:00 La Serena Central Coach Station 10:10 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £26
Cikbus Elité 11h 45m 05:15 La Serena Central Coach Station 17:00 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
  • Did you know that if you travel from La Serena to Antofagasta via Ovalle, you can save more than £2? You can find the corresponding connections below.
    • FlixBus
      15h 50m
      0
      15:00
      La Serena
      Central Coach Station
      16:45
      Ovalle
      Coach Station
      0
      FlixBus
      Economy
      £2
    • Waiting Time 1h 0m
    • FlixBus
      13h 5m
      0
      17:45
      Ovalle
      Coach Station
      06:50
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      FlixBus
      Economy
      £18
    Travel time is 4h 20m longer, but you will save £2

Best Price Offer: The price for the cheapest coach from La Serena to Antofagasta is £16 on 06/01/2026. Flexible travellers save on ticket prices.


Frequency of bus connections between La Serena and Antofagasta

See here how frequent the connections between La Serena and Antofagasta are, during different times and days of the week.
Sunday is the busiest day, with more than 96 daily coaches from La Serena to Antofagasta. Monday has instead the fewest connections, with only 45 daily coaches between La Serena and Antofagasta.
The busiest time of the day is the Evening, with 208 coaches from La Serena to Antofagasta, while Morning sees the fewest connections between La Serena and Antofagasta, with 36 offers.

Facts about coaches from La Serena to Antofagasta

Compare all providers like Pullman San Andres, Pullman Bus and Pluss Chile that travel 64 times every day by bus from La Serena to Antofagasta in one click! Book your bus ticket from La Serena to Antofagasta starting from £16!

Cheapest Bus £16
Fastest Bus 10h 30m
Earliest Coach 05:30
Latest Coach 23:45
Daily Bus Connections 64 Ø
Distance 700.4 km
Coach Companies Pullman San Andres, Pullman Bus, Pluss Chile, Cormar Bus, Cikbus Elité, Nueva Andimar Vip, FlixBus and Ramos Cholele

Cheapest coach connections from La Serena to Antofagasta

Every day, 64 buses from 8 coach companies leave La Serena for Antofagasta: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 15/12/2025 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 15/12
£30
Tuesday 16/12
£25
Wednesday 17/12
£25
Thursday 18/12
£23
Friday 19/12
£21
Saturday 20/12
£24
Sunday 21/12
£22
Monday 22/12
£25
Tuesday 23/12
£24
Wednesday 24/12
£23
Thursday 25/12
£18
Friday 26/12
£19
Saturday 27/12
£21
Sunday 28/12
£24
Monday 29/12
£22
Tuesday 30/12
£18
Wednesday 31/12
£18
Thursday 01/01
£18
Friday 02/01
£18
Saturday 03/01
£20
Sunday 04/01
£18
Monday 05/01
£20
Tuesday 06/01
£16
Wednesday 07/01
£26
Thursday 08/01
£17
Friday 09/01
£17
Saturday 10/01
£19
Sunday 11/01

The cheapest time to travel from La Serena to Antofagasta

See here on which day and which time of the day you can find the cheapest bus ticket from La Serena to Antofagasta, for the next 30 days.
With a price starting from £16, Tuesday is the cheapest day for a coach from La Serena to Antofagasta. Monday instead is the most expensive day with prices starting from £20.
Night is the cheapest day time for bus tickets from La Serena to Antofagasta, with £16. Morning is the most expensive time of the day with prices starting from £26.

How to save money travelling from La Serena to Antofagasta

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from La Serena to Antofagasta in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from La Serena to Antofagasta, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from La Serena to Antofagasta are also emptier.

Latest reviews for coach companies on the route La Serena - Antofagasta

Cormar Bus
Scarleth, 15/06/2025
Aún voy a bordo, pero no podía dejar pasar la oportunidad de felicitar la amabilidad del personal del bus, si bien cumplen con todo los estándares de calidad que ofrecen, mi asiento tuvo un defecto y ... Aún voy a bordo, pero no podía dejar pasar la oportunidad de felicitar la amabilidad del personal del bus, si bien cumplen con todo los estándares de calidad que ofrecen, mi asiento tuvo un defecto y no se podia tirar para atrás, el auxiliar fué informado y de inmediato me resolvió usar otro asiento aunque esté fuera mas caro, incluso nos movió junto a mi pareja para que no estuvieramos separados aunque el asiento de él estaba bien. Muy agradecida por la atención desde que me subí hasta ahora que estoy rumbo a mi hogar. Muchas gracias, no todas las lineas se toman en serio el servicio al cliente, lo digo por experiencia. Un abrazo

All bus stations and stops in La Serena and Antofagasta

The map below shows you where to find all the bus stations in La Serena and Antofagasta.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from La Serena to Antofagasta? Compare all modes of transports from La Serena to Antofagasta.

Service and Comfort on the bus from La Serena to Antofagasta

Want to know which seat classes are available on the coaches from La Serena to Antofagasta? Or which bus companies serve the route La Serena to Antofagasta? Below you will find answers to your questions.

FAQs about the La Serena to Antofagasta bus

How much does a La Serena - Antofagasta coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the La Serena - Antofagasta bus trip is available from £16 and takes 11h 30m. Compare offers and save money!

How much could I save by comparing buses from La Serena to Antofagasta?

The connection La Serena to Antofagasta is offered by 8 companies with ticket prices ranging from £16 to £74. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the La Serena - Antofagasta route on average every day?

Each day, the bus route from La Serena to Antofagasta is offered by roughly 64 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Antofagasta from La Serena take?

The quickest coach from La Serena to Antofagasta is provided by Cormar Bus and takes 10h 30m. Coach tickets for this connection cost £30. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from La Serena to Antofagasta?

The earliest bus to Antofagasta departs from La Serena at 05:30. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from La Serena to Antofagasta?

The latest bus to Antofagasta departs from La Serena at 23:45. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the La Serena - Antofagasta route?

Passengers looking to travel from La Serena to Antofagasta can travel with Pullman San Andres, Pullman Bus and Pluss Chile. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between La Serena and Antofagasta?

You can check all the direct connections between La Serena and Antofagasta by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pullman San Andres, Pullman Bus and Pluss Chile.

What can I take with me on the bus to Antofagasta from La Serena?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the La Serena Antofagasta bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the La Serena Antofagasta bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from La Serena to Antofagasta on your planned travel date.

How does CheckMyBus find the best bus deals from La Serena to Antofagasta?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 64 daily trips between La Serena and Antofagasta. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from La Serena to Antofagasta?

Prices and availability for 64 trips between La Serena and Antofagasta change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route La Serena to Antofagasta

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to La Serena and to Antofagasta

Here’s an overview of the most popular bus routes to La Serena and to Antofagasta. Simply click on the connection of your choice, and you will find all the details about your bus route!

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

deals,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

for

ads

personalisation.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.