Compare all timetables for the bus from Santiago, RM to La Serena
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Condor Bus | 6h 40m | 22:00 | Santiago, RM | Sur Bus Station | 04:40 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Condor Bus goes from Sur Bus Station, Santiago, RM (Chile) at 20/06/2026 22:00:00 to Central Coach Station, La Serena (Chile) arriving at 21/06/2026 04:40:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 40m
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| Pluss Chile | 6h 30m | 13:30 | Santiago, RM | Sur Bus Station | 20:00 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 20/06/2026 13:30:00 to Central Coach Station, La Serena (Chile) arriving at 20/06/2026 20:00:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 30m
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| Cormar Bus | 6h 40m | 23:45 | Santiago, RM | Terminal San Borja | 06:25 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 20/06/2026 23:45:00 to Central Coach Station, La Serena (Chile) arriving at 21/06/2026 06:25:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 40m
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| FlixBus | 6h 10m | 07:30 | Santiago, RM | Terminal San Borja | 13:40 | La Serena | Central Coach Station | Economy | £12 |
A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 20/06/2026 07:30:00 to Central Coach Station, La Serena (Chile) arriving at 20/06/2026 13:40:00. 50 Economy ticket for £12 per person are available. Travel duration is 6h 10m
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| Cikbus Elité | 7h 15m | 07:30 | Santiago, RM | Sur Bus Station | 14:45 | La Serena | Central Coach Station | Premium Economy | £12 |
A Bus from Cikbus Elité goes from Sur Bus Station, Santiago, RM (Chile) at 20/06/2026 07:30:00 to Central Coach Station, La Serena (Chile) arriving at 20/06/2026 14:45:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 7h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Buses Romani | 6h 30m | 10:30 | Santiago, RM | Sur Bus Station | 17:00 | La Serena | Central Coach Station | Premium Economy | £8 |
A Bus from Buses Romani goes from Sur Bus Station, Santiago, RM (Chile) at 21/06/2026 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 21/06/2026 17:00:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 30m
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| Turbus | 6h 10m | 18:30 | Santiago, RM | Terminal Alameda | 00:40 | La Serena | Avda. Fco de Aguirre Station | Premium Economy | £10 |
A Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 21/06/2026 18:30:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 22/06/2026 00:40:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 10m
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| Pluss Chile | 6h 20m | 07:45 | Santiago, RM | Sur Bus Station | 14:05 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 21/06/2026 07:45:00 to Central Coach Station, La Serena (Chile) arriving at 21/06/2026 14:05:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 20m
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| Pullman Bus | 6h 35m | 17:00 | Santiago, RM | Terminal San Borja | 23:35 | La Serena | El Sto, 1060 | First Class | £11 |
A Bus from Pullman Bus goes from Terminal San Borja, Santiago, RM (Chile) at 21/06/2026 17:00:00 to El Sto, 1060, La Serena (Chile) arriving at 21/06/2026 23:35:00. 50 First Class ticket for £11 per person are available. Travel duration is 6h 35m
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| FlixBus | 6h 10m | 07:30 | Santiago, RM | Terminal San Borja | 13:40 | La Serena | Central Coach Station | Economy | £12 |
A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 21/06/2026 07:30:00 to Central Coach Station, La Serena (Chile) arriving at 21/06/2026 13:40:00. 50 Economy ticket for £12 per person are available. Travel duration is 6h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Buses Romani | 6h 25m | 17:30 | Santiago, RM | Sur Bus Station | 23:55 | La Serena | Central Coach Station | Premium Economy | £8 |
A Bus from Buses Romani goes from Sur Bus Station, Santiago, RM (Chile) at 22/06/2026 17:30:00 to Central Coach Station, La Serena (Chile) arriving at 22/06/2026 23:55:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 25m
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| Pluss Chile | 6h 20m | 07:45 | Santiago, RM | Sur Bus Station | 14:05 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 22/06/2026 07:45:00 to Central Coach Station, La Serena (Chile) arriving at 22/06/2026 14:05:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 20m
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| Cormar Bus | 6h 40m | 19:30 | Santiago, RM | Terminal San Borja | 02:10 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 22/06/2026 19:30:00 to Central Coach Station, La Serena (Chile) arriving at 23/06/2026 02:10:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 40m
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| Cikbus Elité | 7h 15m | 07:30 | Santiago, RM | Sur Bus Station | 14:45 | La Serena | Central Coach Station | Premium Economy | £12 |
A Bus from Cikbus Elité goes from Sur Bus Station, Santiago, RM (Chile) at 22/06/2026 07:30:00 to Central Coach Station, La Serena (Chile) arriving at 22/06/2026 14:45:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 7h 15m
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| Serena Mar | 7h 0m | 10:00 | Santiago, RM | Terminal San Borja | 17:00 | La Serena | Central Coach Station | First Class | £13 |
A Bus from Serena Mar goes from Terminal San Borja, Santiago, RM (Chile) at 22/06/2026 10:00:00 to Central Coach Station, La Serena (Chile) arriving at 22/06/2026 17:00:00. 50 First Class ticket for £13 per person are available. Travel duration is 7h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Buses Romani | 6h 30m | 10:30 | Santiago, RM | Terminal San Borja | 17:00 | La Serena | Central Coach Station | Premium Economy | £9 |
A Bus from Buses Romani goes from Terminal San Borja, Santiago, RM (Chile) at 23/06/2026 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 23/06/2026 17:00:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 30m
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| Turbus | 6h 40m | 22:00 | Santiago, RM | Terminal Alameda | 04:40 | La Serena | Avda. Fco de Aguirre Station | Premium Economy | £10 |
A Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 23/06/2026 22:00:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 24/06/2026 04:40:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 40m
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| Condor Bus | 6h 35m | 19:25 | Santiago, RM | Sur Bus Station | 02:00 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Condor Bus goes from Sur Bus Station, Santiago, RM (Chile) at 23/06/2026 19:25:00 to Central Coach Station, La Serena (Chile) arriving at 24/06/2026 02:00:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 35m
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| Cormar Bus | 6h 10m | 13:00 | Santiago, RM | Terminal San Borja | 19:10 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 23/06/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 23/06/2026 19:10:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 10m
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| FlixBus | 6h 10m | 07:30 | Santiago, RM | Terminal San Borja | 13:40 | La Serena | Central Coach Station | Economy | £10 |
A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 23/06/2026 07:30:00 to Central Coach Station, La Serena (Chile) arriving at 23/06/2026 13:40:00. 50 Economy ticket for £10 per person are available. Travel duration is 6h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Buses Romani | 6h 30m | 10:30 | Santiago, RM | Terminal San Borja | 17:00 | La Serena | Central Coach Station | Premium Economy | £9 |
A Bus from Buses Romani goes from Terminal San Borja, Santiago, RM (Chile) at 24/06/2026 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 24/06/2026 17:00:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 30m
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| Turbus | 6h 20m | 06:10 | Santiago, RM | Terminal Alameda | 12:30 | La Serena | Avda. Fco de Aguirre Station | Premium Economy | £10 |
A Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 24/06/2026 06:10:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 24/06/2026 12:30:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 20m
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| Pullman Bus | 6h 20m | 11:00 | Santiago, RM | Terminal San Borja | 17:20 | La Serena | Central Coach Station | Business | £10 |
A Bus from Pullman Bus goes from Terminal San Borja, Santiago, RM (Chile) at 24/06/2026 11:00:00 to Central Coach Station, La Serena (Chile) arriving at 24/06/2026 17:20:00. 50 Business ticket for £10 per person are available. Travel duration is 6h 20m
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| Cormar Bus | 6h 10m | 13:00 | Santiago, RM | Terminal San Borja | 19:10 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 24/06/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 24/06/2026 19:10:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 10m
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| Pluss Chile | 6h 20m | 07:45 | Santiago, RM | Sur Bus Station | 14:05 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 24/06/2026 07:45:00 to Central Coach Station, La Serena (Chile) arriving at 24/06/2026 14:05:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Buses Romani | 6h 30m | 10:30 | Santiago, RM | Terminal San Borja | 17:00 | La Serena | Central Coach Station | Premium Economy | £9 |
A Bus from Buses Romani goes from Terminal San Borja, Santiago, RM (Chile) at 25/06/2026 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 25/06/2026 17:00:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 30m
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| Turbus | 6h 50m | 12:30 | Santiago, RM | Terminal Alameda | 19:20 | La Serena | Avda. Fco de Aguirre Station | Premium Economy | £10 |
A Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 25/06/2026 12:30:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 25/06/2026 19:20:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 50m
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| Cormar Bus | 6h 10m | 13:00 | Santiago, RM | Terminal San Borja | 19:10 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 25/06/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 25/06/2026 19:10:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 10m
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| Pluss Chile | 6h 20m | 07:45 | Santiago, RM | Sur Bus Station | 14:05 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 25/06/2026 07:45:00 to Central Coach Station, La Serena (Chile) arriving at 25/06/2026 14:05:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 20m
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| Condor Bus | 7h 5m | 14:30 | Santiago, RM | Sur Bus Station | 21:35 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Condor Bus goes from Sur Bus Station, Santiago, RM (Chile) at 25/06/2026 14:30:00 to Central Coach Station, La Serena (Chile) arriving at 25/06/2026 21:35:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 7h 5m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pluss Chile | 6h 20m | 07:45 | Santiago, RM | Sur Bus Station | 14:05 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 26/06/2026 07:45:00 to Central Coach Station, La Serena (Chile) arriving at 26/06/2026 14:05:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 20m
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| Cormar Bus | 6h 40m | 19:30 | Santiago, RM | Terminal San Borja | 02:10 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 26/06/2026 19:30:00 to Central Coach Station, La Serena (Chile) arriving at 27/06/2026 02:10:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 40m
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| FlixBus | 6h 10m | 06:15 | Santiago, RM | Terminal San Borja | 12:25 | La Serena | Central Coach Station | Economy | £11 |
A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 26/06/2026 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 26/06/2026 12:25:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 10m
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| Nueva Andimar Vip | 6h 50m | 12:15 | Santiago, RM | Terminal San Borja | 19:05 | La Serena | Central Coach Station | Economy | £12 |
A Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 26/06/2026 12:15:00 to Central Coach Station, La Serena (Chile) arriving at 26/06/2026 19:05:00. 50 Economy ticket for £12 per person are available. Travel duration is 6h 50m
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| Serena Mar | 7h 0m | 10:00 | Santiago, RM | Terminal San Borja | 17:00 | La Serena | Central Coach Station | First Class | £13 |
A Bus from Serena Mar goes from Terminal San Borja, Santiago, RM (Chile) at 26/06/2026 10:00:00 to Central Coach Station, La Serena (Chile) arriving at 26/06/2026 17:00:00. 50 First Class ticket for £13 per person are available. Travel duration is 7h 0m
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Best Price Offer: The price for the cheapest coach from Santiago, RM to La Serena is £8 on 21/06/2026. Flexible travellers save on ticket prices.
Frequency of bus connections between Santiago, RM and La Serena
Facts about coaches from Santiago, RM to La Serena
Compare all providers like Turbus, FlixBus and Pullman Bus that travel 292 times every day by bus from Santiago, RM to La Serena in one click! Book your bus ticket from Santiago, RM to La Serena starting from £8!
| Cheapest Bus | £8 |
| Fastest Bus | 5h 30m |
| Earliest Coach | 01:30 |
| Latest Coach | 23:59 |
| Daily Bus Connections | 292 Ø |
| Distance | 397.3 km |
| Coach Companies | Turbus, FlixBus, Pullman Bus, Pullman San Andres, Pluss Chile, Cikbus Elité, Cormar Bus, Condor Bus, Buses Romani, Nueva Andimar Vip and 4 more. |
Cheapest coach connections from Santiago, RM to La Serena
Every day, 292 buses from 14 coach companies leave Santiago, RM for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 20/06/2026 and for the following days.
The cheapest time to travel from Santiago, RM to La Serena
How to save money travelling from Santiago, RM to La Serena
Book the ticket from Santiago, RM to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago, RM to La Serena, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Santiago, RM to La Serena are also emptier.Beloved bus companies from Santiago, RM to La Serena
Turbus from Santiago, RM to La Serena
Here you will find the key facts about the Turbus bus route Santiago, RM to La Serena:
| Cheapest Price | £10 |
| Fastest Coach | 5h 30m |
| Earliest Coach | 01:30 |
| Last Coach | 23:50 |
| Daily Connections | 41 Ø |
| Found on | 20/06/2026 |
Cormar Bus from Santiago, RM to La Serena
Here you will find the key facts about the Cormar Bus bus route Santiago, RM to La Serena:
| Cheapest Price | £10 |
| Fastest Coach | 5h 50m |
| Earliest Coach | 09:00 |
| Last Coach | 23:59 |
| Daily Connections | 20 Ø |
| Found on | 20/06/2026 |
Buses Romani from Santiago, RM to La Serena
Here you will find the key facts about the Buses Romani bus route Santiago, RM to La Serena:
| Cheapest Price | £8 |
| Fastest Coach | 5h 45m |
| Earliest Coach | 11:30 |
| Last Coach | 23:40 |
| Daily Connections | 22 Ø |
| Found on | 19/06/2026 |
Latest reviews for coach companies on the route Santiago, RM - La Serena
All bus stations and stops in Santiago, RM and La Serena
The map below shows you where to find all the bus stations in Santiago, RM and La Serena.
Service and Comfort on the bus from Santiago, RM to La Serena
FAQs about the Santiago, RM to La Serena bus
How much does a Santiago, RM - La Serena coach trip cost?
How much could I save by comparing buses from Santiago, RM to La Serena?
How many connections are available for the Santiago, RM - La Serena route on average every day?
How long does a bus to La Serena from Santiago, RM take?
What time is the first bus from Santiago, RM to La Serena?
What time is the last coach from Santiago, RM to La Serena?
Which bus companies serve the Santiago, RM - La Serena route?
Is there a direct bus between Santiago, RM and La Serena?
What can I take with me on the bus to La Serena from Santiago, RM?
What equipment is available for the Santiago, RM La Serena bus route?
How does CheckMyBus find the best bus deals from Santiago, RM to La Serena?
How does CheckMyBus technology work for trips from Santiago, RM to La Serena?
Available seat classes which are offered on the bus route Santiago, RM to La Serena
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
Comfortable seating, food and drink service, accompanied generally by ticket flexibility.
Best of the best: you will find the most comfortable accommodation to work or relax during your travel.
More bus routes to Santiago, RM and to La Serena
- Bus Routes to Santiago, RM
- Coaches Coronel to Santiago, RM
- Buses Curanilahue to Santiago, RM
- Bus to Santiago, RM from Curicó
- Bus Lautaro to Santiago, RM
- Buses Litueche to Santiago, RM
- Buses Loncura to Santiago, RM
- Coach Longaví to Santiago, RM
- Bus to Santiago, RM from Los Vilos
- Bus from Molina to Santiago, RM
- Nueva Imperial to Santiago, RM bus
- Bus from Pichidangui to Santiago, RM
- Buses Pitrufquén to Santiago, RM
- Coaches Quillota to Santiago, RM
- Buses Quintero to Santiago, RM
- Coach Saavedra to Santiago, RM
- Buses San Carlos, BI to Santiago, RM
- Bus to Santiago, RM from San Fernando, LI
- São Paulo to Santiago, RM bus
- Coach from Sierra Gorda to Santiago, RM
- Coach Vallenar to Santiago, RM
- Bus Routes to La Serena
- Calama to La Serena bus
- Bus Chillán to La Serena
- Buses Copiapó to La Serena
- Iquique to La Serena coach
- Coach from Mendoza to La Serena
- Quilpué to La Serena bus
- Buses Rancagua to La Serena
- Coaches San Juan, SJ to La Serena
- Coach from Sierra Gorda to La Serena
- Bus to La Serena from Talca, ML
- Bus Temuco to La Serena
- Coach Tocopilla to La Serena
- Coaches Valdivia to La Serena
- Coach to La Serena from Vallenar
- Bus from Valparaíso (CL) to La Serena
