Compare all timetables for the bus from Santiago, RM to La Serena
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Buses Romani | 6h 30m | 13:30 | Santiago, RM | Sur Bus Station | 20:00 | La Serena | Central Coach Station | First Class | £11 |
A Bus from Buses Romani goes from Sur Bus Station, Santiago, RM (Chile) at 18/09/2026 13:30:00 to Central Coach Station, La Serena (Chile) arriving at 18/09/2026 20:00:00. 50 First Class ticket for £11 per person are available. Travel duration is 6h 30m
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| Turbus | 6h 40m | 15:30 | Santiago, RM | Terminal Alameda | 22:10 | La Serena | Avda. Fco de Aguirre Station | Premium Economy | £12 |
A Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 18/09/2026 15:30:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 18/09/2026 22:10:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 40m
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| Pluss Chile | 6h 20m | 07:45 | Santiago, RM | Sur Bus Station | 14:05 | La Serena | Central Coach Station | Premium Economy | £12 |
A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 18/09/2026 07:45:00 to Central Coach Station, La Serena (Chile) arriving at 18/09/2026 14:05:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 20m
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| Cormar Bus | 6h 50m | 07:30 | Santiago, RM | Terminal San Borja | 14:20 | La Serena | Central Coach Station | Premium Economy | £12 |
A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 18/09/2026 07:30:00 to Central Coach Station, La Serena (Chile) arriving at 18/09/2026 14:20:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 50m
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| Serena Mar | 7h 0m | 10:00 | Santiago, RM | Terminal San Borja | 17:00 | La Serena | Central Coach Station | First Class | £12 |
A Bus from Serena Mar goes from Terminal San Borja, Santiago, RM (Chile) at 18/09/2026 10:00:00 to Central Coach Station, La Serena (Chile) arriving at 18/09/2026 17:00:00. 50 First Class ticket for £12 per person are available. Travel duration is 7h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cormar Bus | 6h 50m | 22:55 | Santiago, RM | Terminal San Borja | 05:45 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 19/09/2026 22:55:00 to Central Coach Station, La Serena (Chile) arriving at 20/09/2026 05:45:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 50m
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| Turbus | 6h 20m | 06:10 | Santiago, RM | Terminal Alameda | 12:30 | La Serena | Avda. Fco de Aguirre Station | Premium Economy | £12 |
A Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 19/09/2026 06:10:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 19/09/2026 12:30:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 20m
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| FlixBus | 6h 15m | 06:15 | Santiago, RM | Terminal San Borja | 12:30 | La Serena | Central Coach Station | Economy | £12 |
A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 19/09/2026 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 19/09/2026 12:30:00. 50 Economy ticket for £12 per person are available. Travel duration is 6h 15m
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| Pluss Chile | 6h 20m | 07:45 | Santiago, RM | Sur Bus Station | 14:05 | La Serena | Central Coach Station | Premium Economy | £12 |
A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 19/09/2026 07:45:00 to Central Coach Station, La Serena (Chile) arriving at 19/09/2026 14:05:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 20m
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| Condor Bus | 7h 5m | 14:30 | Santiago, RM | Sur Bus Station | 21:35 | La Serena | Central Coach Station | Premium Economy | £13 |
A Bus from Condor Bus goes from Sur Bus Station, Santiago, RM (Chile) at 19/09/2026 14:30:00 to Central Coach Station, La Serena (Chile) arriving at 19/09/2026 21:35:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 7h 5m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cormar Bus | 6h 50m | 22:55 | Santiago, RM | Terminal San Borja | 05:45 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 20/09/2026 22:55:00 to Central Coach Station, La Serena (Chile) arriving at 21/09/2026 05:45:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 50m
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| Turbus | 6h 20m | 06:10 | Santiago, RM | Terminal Alameda | 12:30 | La Serena | Avda. Fco de Aguirre Station | Premium Economy | £12 |
A Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 20/09/2026 06:10:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 20/09/2026 12:30:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 20m
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| FlixBus | 6h 10m | 06:15 | Santiago, RM | Terminal San Borja | 12:25 | La Serena | Central Coach Station | Economy | £12 |
A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 20/09/2026 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 20/09/2026 12:25:00. 50 Economy ticket for £12 per person are available. Travel duration is 6h 10m
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| Cikbus Elité | 7h 15m | 07:30 | Santiago, RM | Sur Bus Station | 14:45 | La Serena | Central Coach Station | Premium Economy | £12 |
A Bus from Cikbus Elité goes from Sur Bus Station, Santiago, RM (Chile) at 20/09/2026 07:30:00 to Central Coach Station, La Serena (Chile) arriving at 20/09/2026 14:45:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 7h 15m
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| Pluss Chile | 6h 20m | 07:45 | Santiago, RM | Sur Bus Station | 14:05 | La Serena | Central Coach Station | Premium Economy | £12 |
A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 20/09/2026 07:45:00 to Central Coach Station, La Serena (Chile) arriving at 20/09/2026 14:05:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pluss Chile | 6h 30m | 10:25 | Santiago, RM | Sur Bus Station | 16:55 | La Serena | Central Coach Station | Premium Economy | £8 |
A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 21/09/2026 10:25:00 to Central Coach Station, La Serena (Chile) arriving at 21/09/2026 16:55:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 30m
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| Buses Romani | 6h 30m | 10:30 | Santiago, RM | Sur Bus Station | 17:00 | La Serena | Central Coach Station | Premium Economy | £8 |
A Bus from Buses Romani goes from Sur Bus Station, Santiago, RM (Chile) at 21/09/2026 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 21/09/2026 17:00:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 30m
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| Turbus | 7h 10m | 22:30 | Santiago, RM | Terminal Alameda | 05:40 | La Serena | Avda. Fco de Aguirre Station | Premium Economy | £10 |
A Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 21/09/2026 22:30:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 22/09/2026 05:40:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 7h 10m
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| Cormar Bus | 6h 50m | 22:55 | Santiago, RM | Terminal San Borja | 05:45 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 21/09/2026 22:55:00 to Central Coach Station, La Serena (Chile) arriving at 22/09/2026 05:45:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 50m
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| FlixBus | 6h 10m | 06:15 | Santiago, RM | Terminal San Borja | 12:25 | La Serena | Central Coach Station | Economy | £11 |
A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 21/09/2026 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 21/09/2026 12:25:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pluss Chile | 6h 30m | 10:25 | Santiago, RM | Sur Bus Station | 16:55 | La Serena | Central Coach Station | Premium Economy | £8 |
A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 22/09/2026 10:25:00 to Central Coach Station, La Serena (Chile) arriving at 22/09/2026 16:55:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 30m
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| Buses Romani | 6h 30m | 10:30 | Santiago, RM | Sur Bus Station | 17:00 | La Serena | Central Coach Station | Premium Economy | £8 |
A Bus from Buses Romani goes from Sur Bus Station, Santiago, RM (Chile) at 22/09/2026 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 22/09/2026 17:00:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 30m
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| Turbus | 6h 40m | 22:00 | Santiago, RM | Terminal Alameda | 04:40 | La Serena | Avda. Fco de Aguirre Station | Premium Economy | £10 |
A Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 22/09/2026 22:00:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 23/09/2026 04:40:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 40m
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| Condor Bus | 7h 5m | 14:30 | Santiago, RM | Sur Bus Station | 21:35 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Condor Bus goes from Sur Bus Station, Santiago, RM (Chile) at 22/09/2026 14:30:00 to Central Coach Station, La Serena (Chile) arriving at 22/09/2026 21:35:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 7h 5m
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| Cormar Bus | 6h 50m | 22:55 | Santiago, RM | Terminal San Borja | 05:45 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 22/09/2026 22:55:00 to Central Coach Station, La Serena (Chile) arriving at 23/09/2026 05:45:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pluss Chile | 6h 30m | 10:25 | Santiago, RM | Sur Bus Station | 16:55 | La Serena | Central Coach Station | Premium Economy | £8 |
A Bus from Pluss Chile goes from Sur Bus Station, Santiago, RM (Chile) at 23/09/2026 10:25:00 to Central Coach Station, La Serena (Chile) arriving at 23/09/2026 16:55:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 30m
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| Buses Romani | 6h 30m | 10:30 | Santiago, RM | Sur Bus Station | 17:00 | La Serena | Central Coach Station | Premium Economy | £8 |
A Bus from Buses Romani goes from Sur Bus Station, Santiago, RM (Chile) at 23/09/2026 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 23/09/2026 17:00:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 30m
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| FlixBus | 6h 10m | 07:30 | Santiago, RM | Terminal San Borja | 13:40 | La Serena | Central Coach Station | Economy | £9 |
A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 23/09/2026 07:30:00 to Central Coach Station, La Serena (Chile) arriving at 23/09/2026 13:40:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 10m
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| Turbus | 6h 25m | 07:20 | Santiago, RM | Terminal Alameda | 13:45 | La Serena | Avda. Fco de Aguirre Station | Premium Economy | £10 |
A Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 23/09/2026 07:20:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 23/09/2026 13:45:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 25m
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| Cormar Bus | 6h 50m | 22:55 | Santiago, RM | Terminal San Borja | 05:45 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 23/09/2026 22:55:00 to Central Coach Station, La Serena (Chile) arriving at 24/09/2026 05:45:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 6h 10m | 07:30 | Santiago, RM | Terminal San Borja | 13:40 | La Serena | Central Coach Station | Economy | £9 |
A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 24/09/2026 07:30:00 to Central Coach Station, La Serena (Chile) arriving at 24/09/2026 13:40:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 10m
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| Turbus | 6h 20m | 06:10 | Santiago, RM | Terminal Alameda | 12:30 | La Serena | Avda. Fco de Aguirre Station | Premium Economy | £10 |
A Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 24/09/2026 06:10:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 24/09/2026 12:30:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 20m
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| Cormar Bus | 6h 50m | 22:55 | Santiago, RM | Terminal San Borja | 05:45 | La Serena | Central Coach Station | Premium Economy | £10 |
A Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 24/09/2026 22:55:00 to Central Coach Station, La Serena (Chile) arriving at 25/09/2026 05:45:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 6h 50m
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| Andimar | 6h 0m | 07:50 | Santiago, RM | Terminal San Borja | 13:50 | La Serena | Central Coach Station | Economy | £10 |
A Bus from Andimar goes from Terminal San Borja, Santiago, RM (Chile) at 24/09/2026 07:50:00 to Central Coach Station, La Serena (Chile) arriving at 24/09/2026 13:50:00. 50 Economy ticket for £10 per person are available. Travel duration is 6h 0m
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| Pullman San Andres | 6h 15m | 15:30 | Santiago, RM | Terminal San Borja | 21:45 | La Serena | Central Coach Station | Premium Economy | £12 |
A Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 24/09/2026 15:30:00 to Central Coach Station, La Serena (Chile) arriving at 24/09/2026 21:45:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 15m
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Best Price Offer: The price for the cheapest coach from Santiago, RM to La Serena is £8 on 09/10/2026. Flexible travellers save on ticket prices.
Frequency of bus connections between Santiago, RM and La Serena
Facts about coaches from Santiago, RM to La Serena
Compare all providers like Turbus, FlixBus and Pluss Chile that travel 197 times every day by bus from Santiago, RM to La Serena in one click! Book your bus ticket from Santiago, RM to La Serena starting from £8!
| Cheapest Bus | £8 |
| Fastest Bus | 5h 30m |
| Earliest Coach | 01:30 |
| Latest Coach | 23:59 |
| Daily Bus Connections | 197 Ø |
| Distance | 397.3 km |
| Coach Companies | Turbus, FlixBus, Pluss Chile, Pullman San Andres, Condor Bus, Cikbus Elité, Andimar, Cormar Bus, Pullman Bus, Buses Romani and 3 more. |
Cheapest coach connections from Santiago, RM to La Serena
Every day, 197 buses from 13 coach companies leave Santiago, RM for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 18/09/2026 and for the following days.
The cheapest time to travel from Santiago, RM to La Serena
How to save money travelling from Santiago, RM to La Serena
Book the ticket from Santiago, RM to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago, RM to La Serena, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Santiago, RM to La Serena are also emptier.Beloved bus companies from Santiago, RM to La Serena
Turbus from Santiago, RM to La Serena
Here you will find the key facts about the Turbus bus route Santiago, RM to La Serena:
| Cheapest Price | £10 |
| Fastest Coach | 5h 30m |
| Earliest Coach | 01:30 |
| Last Coach | 23:50 |
| Daily Connections | 38 Ø |
| Found on | 17/09/2026 |
Cormar Bus from Santiago, RM to La Serena
Here you will find the key facts about the Cormar Bus bus route Santiago, RM to La Serena:
| Cheapest Price | £10 |
| Fastest Coach | 5h 50m |
| Earliest Coach | 07:30 |
| Last Coach | 23:59 |
| Daily Connections | 10 Ø |
| Found on | 17/09/2026 |
Latest reviews for coach companies on the route Santiago, RM - La Serena
All bus stations and stops in Santiago, RM and La Serena
The map below shows you where to find all the bus stations in Santiago, RM and La Serena.
Service and Comfort on the bus from Santiago, RM to La Serena
FAQs about the Santiago, RM to La Serena bus
How much does a Santiago, RM - La Serena coach trip cost?
How much could I save by comparing buses from Santiago, RM to La Serena?
How many connections are available for the Santiago, RM - La Serena route on average every day?
How long does a bus to La Serena from Santiago, RM take?
What time is the first bus from Santiago, RM to La Serena?
What time is the last coach from Santiago, RM to La Serena?
Which bus companies serve the Santiago, RM - La Serena route?
Is there a direct bus between Santiago, RM and La Serena?
What can I take with me on the bus to La Serena from Santiago, RM?
What equipment is available for the Santiago, RM La Serena bus route?
How does CheckMyBus find the best bus deals from Santiago, RM to La Serena?
How does CheckMyBus technology work for trips from Santiago, RM to La Serena?
Available seat classes which are offered on the bus route Santiago, RM to La Serena
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
Best of the best: you will find the most comfortable accommodation to work or relax during your travel.
More bus routes to Santiago, RM and to La Serena
- Bus Routes to Santiago, RM
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- Buses Curanilahue to Santiago, RM
- Bus to Santiago, RM from Curicó
- Bus from La Calera to Santiago, RM
- Labranza to Santiago, RM bus
- Bus Lautaro to Santiago, RM
- Coach Longaví to Santiago, RM
- Coach from Pichicuy to Santiago, RM
- Bus from Pichidangui to Santiago, RM
- Buses Pitrufquén to Santiago, RM
- Coaches Quillota to Santiago, RM
- Buses Quintero to Santiago, RM
- Coach Saavedra to Santiago, RM
- Buses San Carlos, BI to Santiago, RM
- Bus to Santiago, RM from San Fernando, LI
- Coach from Sierra Gorda to Santiago, RM
- Tongoy, CO to Santiago, RM bus
- Coach Vallenar to Santiago, RM
- Bus Routes to La Serena
- Bus to La Serena from Alto Hospicio
- Bus Antofagasta to La Serena
- Coach Arica, AP to La Serena
- Concepción to La Serena bus
- Buses Copiapó to La Serena
- Coaches Ovalle to La Serena
- Bus to La Serena from Pozo Almonte
- Bus Puerto Montt to La Serena
- Buses Rancagua to La Serena
- Bus to La Serena from Salamanca, CO
- Coaches San Juan, SJ to La Serena
- Coach from Sierra Gorda to La Serena
- Bus to La Serena from Talca, ML
- Bus Temuco to La Serena
- Coach Tocopilla to La Serena
- Coach to La Serena from Vallenar
