Bus tickets Santiago, RM to La Serena from £7

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Compare all timetables for the bus from Santiago, RM to La Serena

Here is a selection of the cheapest bus trips from the schedule from Santiago, RM to La Serena from various bus operators like FlixBus, Pullman Bus or Cikbus Elité for the next days.

today
£7
tomorrow
£8
Sunday
£8
Monday
£8
Tuesday
£10
Wednesday
£10
Thursday
£8

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Buses Romani 6h 30m 10:30 Santiago, RM Sur Bus Station 17:00 La Serena Central Coach Station  Premium Economy £7
Cormar Bus 6h 30m 12:00 Santiago, RM Terminal San Borja 18:30 La Serena Central Coach Station  Premium Economy £10
Pullman Bus 6h 20m 11:00 Santiago, RM Terminal San Borja 17:20 La Serena El Sto, 1060  First Class £11
FlixBus 6h 10m 19:15 Santiago, RM Terminal San Borja 01:25 La Serena Central Coach Station  Economy £11
Turbus 7h 55m 09:30 Santiago, RM Terminal San Borja 17:25 La Serena Avda. Fco de Aguirre Station  Premium Economy £13

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Turbus 6h 10m 18:30 Santiago, RM Terminal Alameda 00:40 La Serena Avda. Fco de Aguirre Station  Premium Economy £8
Condor Bus 7h 5m 14:30 Santiago, RM Sur Bus Station 21:35 La Serena Central Coach Station  Premium Economy £8
FlixBus 6h 10m 18:10 Santiago, RM Terminal San Borja 00:20 La Serena Central Coach Station  Premium Economy £10
Cormar Bus 6h 30m 08:30 Santiago, RM Terminal San Borja 15:00 La Serena Central Coach Station  First Class £12
Buses Paravias 6h 20m 12:30 Santiago, RM Terminal San Borja 18:50 La Serena Central Coach Station  Business £13

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Buses Romani 6h 30m 10:30 Santiago, RM Terminal San Borja 17:00 La Serena Central Coach Station  Business £8
Cormar Bus 6h 30m 12:00 Santiago, RM Terminal San Borja 18:30 La Serena Central Coach Station  Premium Economy £10
FlixBus 6h 10m 06:15 Santiago, RM Terminal San Borja 12:25 La Serena Central Coach Station  Economy £11
Cikbus Elité 6h 5m 09:00 Santiago, RM Sur Bus Station 15:05 La Serena Central Coach Station  Premium Economy £13
Pullman San Andres 6h 15m 15:30 Santiago, RM Terminal San Borja 21:45 La Serena Central Coach Station  Premium Economy £13

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Buses Romani 6h 30m 10:30 Santiago, RM Terminal San Borja 17:00 La Serena Central Coach Station  Business £8
Turbus 5h 45m 21:30 Santiago, RM Terminal Alameda 03:15 La Serena Avda. Fco de Aguirre Station  Premium Economy £9
FlixBus 6h 10m 06:15 Santiago, RM Terminal San Borja 12:25 La Serena Central Coach Station  Economy £10
Cormar Bus 6h 10m 13:00 Santiago, RM Terminal San Borja 19:10 La Serena Central Coach Station  Premium Economy £10
Cikbus Elité 6h 0m 23:45 Santiago, RM Sur Bus Station 05:45 La Serena Central Coach Station  Premium Economy £13

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 6h 10m 06:15 Santiago, RM Terminal San Borja 12:25 La Serena Central Coach Station  Economy £10
Cormar Bus 6h 30m 12:00 Santiago, RM Terminal San Borja 18:30 La Serena Central Coach Station  Premium Economy £10
Pullman San Andres 6h 15m 15:30 Santiago, RM Terminal San Borja 21:45 La Serena Central Coach Station  Premium Economy £13
Serena Mar 7h 0m 10:00 Santiago, RM Terminal San Borja 17:00 La Serena Central Coach Station  First Class £13
Buses Paravias 6h 20m 12:30 Santiago, RM Terminal San Borja 18:50 La Serena Central Coach Station  Business £13
  • Did you know that if you travel from Coquimbo to Santiago, RM via La Serena, you can save more than £7? You will find the corresponding connections below.
    • Save more than 70%
      0h 35m
      0 km
      13:30
      Coquimbo
      Coach Station
      14:05
      La Serena
      El Sto, 1060
      392 km
      Santiago, RM
      Premium Economy
      £3
  • Did you know that if you travel from Santiago, RM to La Serena via Ovalle, you can save more than £1? You can find the corresponding connections below.
    • FlixBus
      7h 20m
      0
      06:45
      Santiago, RM
      Terminal San Borja
      12:00
      Ovalle
      Coach Station
      0
      FlixBus
      Economy
      £6
      • Waiting Time 0h 20m
    • kupos.cl
      1h 45m
      0
      12:20
      Ovalle
      Coach Station
      14:05
      La Serena
      Avda. Fco de Aguirre Station
      0
      kupos.cl
      Premium Economy
      £3
    Travel time is 1h 10m longer, but you will save £1

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 6h 10m 13:00 Santiago, RM Terminal San Borja 19:10 La Serena Central Coach Station  Premium Economy £10
FlixBus 6h 10m 06:15 Santiago, RM Terminal San Borja 12:25 La Serena Central Coach Station  Economy £11
Pullman San Andres 6h 15m 14:00 Santiago, RM Terminal San Borja 20:15 La Serena Central Coach Station  Premium Economy £13
Cikbus Elité 7h 15m 07:30 Santiago, RM Sur Bus Station 14:45 La Serena Central Coach Station  Premium Economy £15
Buses Romani 6h 30m 11:30 Santiago, RM Terminal San Borja 18:00 La Serena Central Coach Station  Business £18
  • Did you know that if you travel from Santiago, RM to La Serena via Ovalle, you can save more than £1? You can find the corresponding connections below.
    • FlixBus
      7h 20m
      0
      06:45
      Santiago, RM
      Terminal San Borja
      12:00
      Ovalle
      Coach Station
      0
      FlixBus
      Economy
      £6
      • Waiting Time 0h 20m
    • kupos.cl
      1h 45m
      0
      12:20
      Ovalle
      Coach Station
      14:05
      La Serena
      Avda. Fco de Aguirre Station
      0
      kupos.cl
      Premium Economy
      £3
    Travel time is 1h 10m longer, but you will save £1

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Turbus 6h 40m 22:00 Santiago, RM Terminal Alameda 04:40 La Serena Avda. Fco de Aguirre Station  Premium Economy £8
Condor Bus 7h 5m 14:30 Santiago, RM Sur Bus Station 21:35 La Serena Central Coach Station  Premium Economy £8
FlixBus 6h 10m 18:10 Santiago, RM Terminal San Borja 00:20 La Serena Central Coach Station  Premium Economy £10
Pullman San Andres 6h 15m 15:30 Santiago, RM Terminal San Borja 21:45 La Serena Central Coach Station  Premium Economy £10
Cormar Bus 6h 10m 13:00 Santiago, RM Terminal San Borja 19:10 La Serena Central Coach Station  Premium Economy £10

Best Price Offer: The price for the cheapest coach from Santiago, RM to La Serena is £7 on 19/12/2025. Flexible travellers save on ticket prices.


Frequency of bus connections between Santiago, RM and La Serena

See here how frequent the connections between Santiago, RM and La Serena are, during different times and days of the week.
Sunday is the busiest day, with more than 315 daily coaches from Santiago, RM to La Serena. Wednesday has instead the fewest connections, with only 152 daily coaches between Santiago, RM and La Serena.
The busiest time of the day is the Evening, with 786 coaches from Santiago, RM to La Serena, while Night sees the fewest connections between Santiago, RM and La Serena, with 11 offers.

Facts about coaches from Santiago, RM to La Serena

Compare all providers like FlixBus, Pullman Bus and Cikbus Elité that travel 255 times every day by bus from Santiago, RM to La Serena in one click! Book your bus ticket from Santiago, RM to La Serena starting from £7!

Cheapest Bus £7
Fastest Bus 5h 30m
Earliest Coach 09:30
Latest Coach 23:59
Daily Bus Connections 255 Ø
Distance 397.3 km
Coach Companies FlixBus, Pullman Bus, Cikbus Elité, Turbus, Pluss Chile, Pullman San Andres, Buses Romani, Cormar Bus, Condor Bus, Nueva Andimar Vip and 4 more.

Cheapest coach connections from Santiago, RM to La Serena

Every day, 255 buses from 14 coach companies leave Santiago, RM for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 19/12/2025 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 15/12
Tuesday 16/12
Wednesday 17/12
Thursday 18/12
Friday 19/12
£11
Saturday 20/12
£8
Sunday 21/12
£8
Monday 22/12
£9
Tuesday 23/12
£10
Wednesday 24/12
£11
Thursday 25/12
£8
Friday 26/12
£8
Saturday 27/12
£13
Sunday 28/12
£12
Monday 29/12
£9
Tuesday 30/12
£10
Wednesday 31/12
£10
Thursday 01/01
£10
Friday 02/01
£8
Saturday 03/01
£9
Sunday 04/01
£10
Monday 05/01
£9
Tuesday 06/01
£8
Wednesday 07/01
£8
Thursday 08/01
£8
Friday 09/01
£9
Saturday 10/01
£8
Sunday 11/01

The cheapest time to travel from Santiago, RM to La Serena

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago, RM to La Serena, for the next 30 days.
With a price starting from £7, Friday is the cheapest day for a coach from Santiago, RM to La Serena. Tuesday instead is the most expensive day with prices starting from £8.
Morning is the cheapest day time for bus tickets from Santiago, RM to La Serena, with £7. Evening is the most expensive time of the day with prices starting from £8.

How to save money travelling from Santiago, RM to La Serena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago, RM to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago, RM to La Serena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Santiago, RM to La Serena are also emptier.

Beloved bus companies from Santiago, RM to La Serena

These are the most booked bus companies between Santiago, RM to La Serena from our users.

Cikbus Elité from Santiago, RM to La Serena

Cikbus Elité

Here you will find the key facts about the Cikbus Elité bus route Santiago, RM to La Serena:

Cheapest Price £13
Fastest Coach 6h 0m
Earliest Coach 10:00
Last Coach 23:45
Daily Connections 36 Ø
Found on 19/12/2025

Buses Romani from Santiago, RM to La Serena

Buses Romani

Here you will find the key facts about the Buses Romani bus route Santiago, RM to La Serena:

Cheapest Price £7
Fastest Coach 5h 45m
Earliest Coach 10:30
Last Coach 23:40
Daily Connections 16 Ø
Found on 19/12/2025

Latest reviews for coach companies on the route Santiago, RM - La Serena

Nueva Andimar Vip
jonathan, 04/09/2025

HORRIBLE

FlixBus
Rocío Santana , 22/11/2024
Malísima experiencia con un hombre del personal, a media hora de haber salido del terminal San Borja mi hija necesito usar el baño a lo que respondió que el baño era solo para ruta y que estaban aburr ... Malísima experiencia con un hombre del personal, a media hora de haber salido del terminal San Borja mi hija necesito usar el baño a lo que respondió que el baño era solo para ruta y que estaban aburridos que las personas le hicieran ( del 2) , cosa que entiendo perfectamente, pero fue bastante grosero y retador y con la voz alzada, pésima experiencia no respondí porque estaba con mi hija pero nunca más usaré este servicio.
Condor Bus
Camila , 07/11/2024
Pésima experiencia, en bus de verdad tienen un olor demasiado hediondo es insoportable, además no tienen aire acondicionado y hizo mucho frío yo viaje de noche y pase demasiado frío, gente del bus le ... Pésima experiencia, en bus de verdad tienen un olor demasiado hediondo es insoportable, además no tienen aire acondicionado y hizo mucho frío yo viaje de noche y pase demasiado frío, gente del bus le pidió al chofer copiloto subir la temperatura y jamás lo hizo La verdad nunca mas viajo con ellos
Pullman San Andres
Ernesto, 12/09/2024
Viajo regularmente entre Santiago y La Serena y v/v, en Buses salón cama. es la primera vez que tomo esta empresa y en realidad no volvería a tomarla. Las razones: GPS DESCONECTADO por tanto se DESC ... Viajo regularmente entre Santiago y La Serena y v/v, en Buses salón cama. es la primera vez que tomo esta empresa y en realidad no volvería a tomarla. Las razones: GPS DESCONECTADO por tanto se DESCONOCE el nombre del conductor, cuanto tiempo lleva conduciendo y a qué velocidad estamos transitando. Maquina NO SANITIZADA da desconfianza sentarse en los asientos con los apoyacabezas negros de suciedad y sin funda de protección lo mismo pasa con los cinturones de seguridad también muy sucios. Esta máquina salió a las 12:30 PM desde terminal San Borja con destino a Arica, (yo bajo el La Serena)
Pluss Chile
Sramirez , 12/09/2024
Voy viajando en Salón cama y literal que voy atrapada entre mi asiento y el respaldo del asiento en frente de mi. El nivel de inclinación de los asientos supera lo permitido quedando prácticamente atr ... Voy viajando en Salón cama y literal que voy atrapada entre mi asiento y el respaldo del asiento en frente de mi. El nivel de inclinación de los asientos supera lo permitido quedando prácticamente atrapada, tienes el respaldo de la persona que va delante sobre tus piernas sin poder moverte y eso que soy delgada, imagino a alguien de mayor dimensión o un adulto mayor, además del mal olor en el bus es horrible. No viajo más en esta línea.

All bus stations and stops in Santiago, RM and La Serena

The map below shows you where to find all the bus stations in Santiago, RM and La Serena.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Santiago, RM to La Serena? Compare all modes of transports from Santiago, RM to La Serena.

Service and Comfort on the bus from Santiago, RM to La Serena

Want to know which seat classes are available on the coaches from Santiago, RM to La Serena? Or which bus companies serve the route Santiago, RM to La Serena? Below you will find answers to your questions.

FAQs about the Santiago, RM to La Serena bus

How much does a Santiago, RM - La Serena coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Santiago, RM - La Serena bus trip is available from £7 and takes 6h 30m. Compare offers and save money!

How much could I save by comparing buses from Santiago, RM to La Serena?

The connection Santiago, RM to La Serena is offered by 14 companies with ticket prices ranging from £7 to £67. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Santiago, RM - La Serena route on average every day?

Each day, the bus route from Santiago, RM to La Serena is offered by roughly 255 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to La Serena from Santiago, RM take?

The quickest coach from Santiago, RM to La Serena is provided by Gentour and takes 5h 30m. Coach tickets for this connection cost £67. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Santiago, RM to La Serena?

The earliest bus to La Serena departs from Santiago, RM at 09:30. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Santiago, RM to La Serena?

The latest bus to La Serena departs from Santiago, RM at 23:59. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Santiago, RM - La Serena route?

Passengers looking to travel from Santiago, RM to La Serena can travel with FlixBus, Pullman Bus and Cikbus Elité. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Santiago, RM and La Serena?

You can check all the direct connections between Santiago, RM and La Serena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Pullman Bus and Cikbus Elité.

What can I take with me on the bus to La Serena from Santiago, RM?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Santiago, RM La Serena bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago, RM La Serena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago, RM to La Serena on your planned travel date.

How does CheckMyBus find the best bus deals from Santiago, RM to La Serena?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 255 daily trips between Santiago, RM and La Serena. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santiago, RM to La Serena?

Prices and availability for 255 trips between Santiago, RM and La Serena change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santiago, RM to La Serena

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Santiago, RM and to La Serena

Here’s an overview of the most popular bus routes to Santiago, RM and to La Serena. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus from Coquimbo to Santiago, RM Bus from Coquimbo to Santiago, RM
Buses Copiapó to Santiago, RM Buses Copiapó to Santiago, RM
Villarrica (CL) to Santiago, RM bus Villarrica (CL) to Santiago, RM bus
Bus Lautaro to Santiago, RM Bus Lautaro to Santiago, RM
Bus from Valparaíso (CL) to La Serena Bus from Valparaíso (CL) to La Serena
Buses Copiapó to La Serena Buses Copiapó to La Serena
Iquique to La Serena coach Iquique to La Serena coach
Coaches Ovalle to La Serena Coaches Ovalle to La Serena
Popular Airport Transfers to Santiago, RM and to La Serena
CheckMyBus › Coaches in Chile › Coach to Santiago, RM › Coach to La Serena

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