Bus and Coach from Mendoza to La Serena: Compare all prices

Compare all timetables for the bus from Mendoza to La Serena

Here is a selection of the cheapest bus trips from the schedule from Mendoza to La Serena from various bus operators like CATA Internacional for the next days.

today

tomorrow

Tuesday

Wednesday

Thursday

Friday

Saturday

£62

Cheapest bus trips Saturday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	CATA Internacional	11h 45m	20:15	Mendoza	Bus Station	08:00	La Serena	Central Coach Station		Basic	£62	A Bus from CATA Internacional goes from Bus Station, Mendoza (Argentina) at 20/12/2025 20:15:00 to Central Coach Station, La Serena (Chile) arriving at 21/12/2025 08:00:00. 50 Basic ticket for £62 per person are available. Travel duration is 11h 45m

Did you know that if you travel from Mendoza to La Serena via Santiago, RM, you can save more than £44? You can find the corresponding connections below.
- DeÔnibus
  
  15h 15m
  
  0
  
  21:10
  
  Mendoza
  Hotel Hyatt
  
  04:10
  
  Santiago, RM
  Sur Bus Station
  
  0
  
  Basic
  
  £9
  
  A Bus from DeÔnibus goes from Hotel Hyatt, Mendoza (Argentina) at 16/12/2025 21:10:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 17/12/2025 04:10:00. 50 Basic ticket for £9 per person are available. Travel duration is 7h 0m
- FlixBus
  
  6h 10m
  
  0
  
  06:15
  
  Santiago, RM
  Terminal San Borja
  
  12:25
  
  La Serena
  Central Coach Station
  
  0
  
  Economy
  
  £9
  
  A Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 17/12/2025 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 17/12/2025 12:25:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 10m
Travel time is 3h 30m longer, but you will save £44

Best Price Offer: The price for the cheapest coach from Mendoza to La Serena is £47 on 13/12/2025. Flexible travellers save on ticket prices.

Facts about coaches from Mendoza to La Serena

Compare all providers like CATA Internacional that travel 8 times every day by bus from Mendoza to La Serena in one click! Book your bus ticket from Mendoza to La Serena starting from £47!

Cheapest Bus	£47
Fastest Bus	11h 45m
Earliest Coach	20:15
Latest Coach	20:15
Daily Bus Connections	8 Ø
Distance	403.0 km
Coach Companies	CATA Internacional

Cheapest coach connections from Mendoza to La Serena

Every day, 8 buses from 1 coach companies leave Mendoza for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 14/12/2025 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 08/12

Tuesday 09/12

Wednesday 10/12

Thursday 11/12

Friday 12/12

Saturday 13/12

Sunday 14/12

Monday 15/12

Tuesday 16/12

Wednesday 17/12

Thursday 18/12

Friday 19/12

Saturday 20/12

£72

Sunday 21/12

Monday 22/12

Tuesday 23/12

Wednesday 24/12

Thursday 25/12

Friday 26/12

Saturday 27/12

£72

Sunday 28/12

£72

Monday 29/12

Tuesday 30/12

Wednesday 31/12

Thursday 01/01

£72

Friday 02/01

Saturday 03/01

£72

Sunday 04/01

How to save money travelling from Mendoza to La Serena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mendoza to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mendoza to La Serena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Mendoza to La Serena are also emptier.

All bus stations and stops in Mendoza and La Serena

The map below shows you where to find all the bus stations in Mendoza and La Serena.

Bus Station

Juan B. Alberdi s/n

Hotel Internacional

Av. Sarmiento 720

Hotel Hyatt

Chile 1124

Hotel NH Cordillera

1324 1324

Casa Juri

Avda. Fco de Aguirre Station

Avenida Francisco de Aguirre 410

Central Coach Station

Avenida El Santo 1475

El Sto, 1060

terminal de buses covalle bus

Rotonda

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Mendoza to La Serena? Compare all modes of transports from Mendoza to La Serena.

Service and Comfort on the bus from Mendoza to La Serena

Want to know which seat classes are available on the coaches from Mendoza to La Serena? Or which bus companies serve the route Mendoza to La Serena? Below you will find answers to your questions.

FAQs about the Mendoza to La Serena bus

How much does a Mendoza - La Serena coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Mendoza - La Serena bus trip is available from £47 and takes 11h 45m. Compare offers and save money!

How much could I save by comparing buses from Mendoza to La Serena?

The connection Mendoza to La Serena is offered by 1 companies with ticket prices ranging from £47 to £93. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Mendoza - La Serena route on average every day?

Each day, the bus route from Mendoza to La Serena is offered by roughly 8 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to La Serena from Mendoza take?

The quickest coach from Mendoza to La Serena is provided by CATA Internacional and takes 11h 45m. Coach tickets for this connection cost £62. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Mendoza to La Serena?

The earliest bus to La Serena departs from Mendoza at 20:15. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Mendoza to La Serena?

The latest bus to La Serena departs from Mendoza at 20:15. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Mendoza - La Serena route?

Passengers looking to travel from Mendoza to La Serena can travel with CATA Internacional. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Mendoza and La Serena?

You can check all the direct connections between Mendoza and La Serena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: CATA Internacional.

What can I take with me on the bus to La Serena from Mendoza?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Mendoza La Serena bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Mendoza La Serena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mendoza to La Serena on your planned travel date.

Available seat classes which are offered on the bus route Mendoza to La Serena

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

More bus routes to Mendoza and to La Serena

Here’s an overview of the most popular bus routes to Mendoza and to La Serena. Simply click on the connection of your choice, and you will find all the details about your bus route!