What is the best way to travel from La Serena to Antofagasta?
Looking for a trip? Check and compare all the available Buses and Flights to Antofagasta from La Serena. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 9 available companies to find your perfect trip!
What is the cheapest way to reach Antofagasta from La Serena?
You can reach Antofagasta with just £19 by taking a Bus from Pullman Bus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Pullman Bus11h 50m021:00La SerenaEl Sto, 106008:50AntofagastaCamus Coach Station0First ClassA Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 21/08/2026 21:00:00 to Camus Coach Station, Antofagasta (Chile) arriving at 22/08/2026 08:50:00. 50 First Class ticket for £19 per person are available. Travel duration is 11h 50m
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Cormar Bus11h 50m014:20La SerenaCentral Coach Station02:10AntofagastaCamus Coach Station0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 21/08/2026 14:20:00 to Camus Coach Station, Antofagasta (Chile) arriving at 22/08/2026 02:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 11h 50m
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Pluss Chile10h 45m001:50La SerenaCentral Coach Station12:35AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Coach Station, La Serena (Chile) at 21/08/2026 01:50:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 21/08/2026 12:35:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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Pullman San Andres12h 10m022:00La SerenaCentral Coach Station10:10AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 21/08/2026 22:00:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 22/08/2026 10:10:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
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Cikbus Elité11h 45m005:15La SerenaCentral Coach Station17:00AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 21/08/2026 05:15:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 21/08/2026 17:00:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 11h 45m
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LATAM Brasil1h 24m016:27La Florida, La Serena AirportLa Florida, La Serena Airport17:51Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 21/08/2026 16:27:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 21/08/2026 17:51:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 24m
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LAN Airlines1h 24m016:27La Florida, La Serena AirportLa Florida, La Serena Airport17:51Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 21/08/2026 16:27:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 21/08/2026 17:51:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 24m
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Sky Airline15h 3m019:59La Florida, La Serena AirportLa Florida, La Serena Airport11:02Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 21/08/2026 19:59:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 22/08/2026 11:02:00. 50 Economy ticket for £142 per person are available. Travel duration is 15h 3m
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LAN Airlines7h 30m009:45La Florida, La Serena AirportLa Florida, La Serena Airport17:15Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 21/08/2026 09:45:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 21/08/2026 17:15:00. 50 Economy ticket for £144 per person are available. Travel duration is 7h 30m
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LATAM Brasil6h 59m009:45La Florida, La Serena AirportLa Florida, La Serena Airport16:44Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 21/08/2026 09:45:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 21/08/2026 16:44:00. 50 Economy ticket for £148 per person are available. Travel duration is 6h 59m
Cheapest Buses Friday
Cheapest Flights Friday
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Andimar11h 35m014:00La SerenaCentral Coach Station01:35AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Andimar goes from Central Coach Station, La Serena (Chile) at 22/08/2026 14:00:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 23/08/2026 01:35:00. 50 Economy ticket for £24 per person are available. Travel duration is 11h 35m
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Cormar Bus11h 50m005:55La SerenaCentral Coach Station17:45AntofagastaCamus Coach Station0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 22/08/2026 05:55:00 to Camus Coach Station, Antofagasta (Chile) arriving at 22/08/2026 17:45:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 11h 50m
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Pullman San Andres12h 10m002:30La SerenaCentral Coach Station14:40AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 22/08/2026 02:30:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 22/08/2026 14:40:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
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Pullman Bus11h 50m021:00La SerenaEl Sto, 106008:50AntofagastaCamus Coach Station0First ClassA Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 22/08/2026 21:00:00 to Camus Coach Station, Antofagasta (Chile) arriving at 23/08/2026 08:50:00. 50 First Class ticket for £26 per person are available. Travel duration is 11h 50m
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Cikbus Elité11h 45m005:15La SerenaCentral Coach Station17:00AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 22/08/2026 05:15:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 22/08/2026 17:00:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 11h 45m
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JetSmart20h 49m010:51La Florida, La Serena AirportLa Florida, La Serena Airport07:40Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 22/08/2026 10:51:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 23/08/2026 07:40:00. 50 Economy ticket for £115 per person are available. Travel duration is 20h 49m
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Sky Airline18h 26m013:14La Florida, La Serena AirportLa Florida, La Serena Airport07:40Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 22/08/2026 13:14:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 23/08/2026 07:40:00. 50 Economy ticket for £130 per person are available. Travel duration is 18h 26m
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LAN Airlines11h 23m020:17La Florida, La Serena AirportLa Florida, La Serena Airport07:40Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 22/08/2026 20:17:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 23/08/2026 07:40:00. 50 Economy ticket for £132 per person are available. Travel duration is 11h 23m
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LATAM Brasil11h 23m020:17La Florida, La Serena AirportLa Florida, La Serena Airport07:40Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 22/08/2026 20:17:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 23/08/2026 07:40:00. 50 Economy ticket for £141 per person are available. Travel duration is 11h 23m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Cormar Bus11h 50m005:55La SerenaCentral Coach Station17:45AntofagastaCamus Coach Station0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 23/08/2026 05:55:00 to Camus Coach Station, Antofagasta (Chile) arriving at 23/08/2026 17:45:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 11h 50m
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Andimar11h 35m014:00La SerenaCentral Coach Station01:35AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Andimar goes from Central Coach Station, La Serena (Chile) at 23/08/2026 14:00:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 24/08/2026 01:35:00. 50 Economy ticket for £24 per person are available. Travel duration is 11h 35m
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Pluss Chile10h 45m001:50La SerenaCentral Coach Station12:35AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Coach Station, La Serena (Chile) at 23/08/2026 01:50:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 23/08/2026 12:35:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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FlixBus11h 55m022:15La SerenaCentral Coach Station10:10AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Coach Station, La Serena (Chile) at 23/08/2026 22:15:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 24/08/2026 10:10:00. 50 Economy ticket for £25 per person are available. Travel duration is 11h 55m
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Pullman San Andres12h 10m002:30La SerenaCentral Coach Station14:40AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 23/08/2026 02:30:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 23/08/2026 14:40:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
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LAN Airlines1h 24m019:33La Florida, La Serena AirportLa Florida, La Serena Airport20:57Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 23/08/2026 19:33:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 23/08/2026 20:57:00. 50 Economy ticket for £27 per person are available. Travel duration is 1h 24m
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Sky Airline1h 19m012:21La Florida, La Serena AirportLa Florida, La Serena Airport13:40Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 23/08/2026 12:21:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 23/08/2026 13:40:00. 50 Economy ticket for £110 per person are available. Travel duration is 1h 19m
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JetSmart1h 22m019:55La Florida, La Serena AirportLa Florida, La Serena Airport21:17Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 23/08/2026 19:55:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 23/08/2026 21:17:00. 50 Economy ticket for £230 per person are available. Travel duration is 1h 22m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Andimar11h 35m017:10La SerenaCentral Coach Station04:45AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Andimar goes from Central Coach Station, La Serena (Chile) at 24/08/2026 17:10:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 25/08/2026 04:45:00. 50 Economy ticket for £22 per person are available. Travel duration is 11h 35m
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Pluss Chile10h 45m001:50La SerenaCentral Coach Station12:35AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Coach Station, La Serena (Chile) at 24/08/2026 01:50:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 24/08/2026 12:35:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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FlixBus11h 55m022:15La SerenaCentral Coach Station10:10AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Coach Station, La Serena (Chile) at 24/08/2026 22:15:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 25/08/2026 10:10:00. 50 Economy ticket for £25 per person are available. Travel duration is 11h 55m
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Pullman San Andres12h 10m002:30La SerenaCentral Coach Station14:40AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 24/08/2026 02:30:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 24/08/2026 14:40:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
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Cormar Bus11h 50m005:55La SerenaCentral Coach Station17:45AntofagastaCamus Coach Station0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 24/08/2026 05:55:00 to Camus Coach Station, Antofagasta (Chile) arriving at 24/08/2026 17:45:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 11h 50m
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LAN Airlines1h 23m009:59La Florida, La Serena AirportLa Florida, La Serena Airport11:22Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 24/08/2026 09:59:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 24/08/2026 11:22:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 23m
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LAN Airlines23h 7m022:32La Florida, La Serena AirportLa Florida, La Serena Airport21:39Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 24/08/2026 22:32:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 25/08/2026 21:39:00. 50 Economy ticket for £120 per person are available. Travel duration is 23h 7m
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LATAM Brasil23h 7m022:32La Florida, La Serena AirportLa Florida, La Serena Airport21:39Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 24/08/2026 22:32:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 25/08/2026 21:39:00. 50 Economy ticket for £128 per person are available. Travel duration is 23h 7m
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JetSmart12h 37m020:35La Florida, La Serena AirportLa Florida, La Serena Airport09:12Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 24/08/2026 20:35:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 25/08/2026 09:12:00. 50 Economy ticket for £152 per person are available. Travel duration is 12h 37m
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JetSmart19h 44m010:51La Florida, La Serena AirportLa Florida, La Serena Airport06:35Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 24/08/2026 10:51:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 25/08/2026 06:35:00. 50 Economy ticket for £157 per person are available. Travel duration is 19h 44m
Cheapest Buses Monday
Cheapest Flights Monday
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Andimar11h 35m017:10La SerenaCentral Coach Station04:45AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Andimar goes from Central Coach Station, La Serena (Chile) at 25/08/2026 17:10:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 26/08/2026 04:45:00. 50 Economy ticket for £22 per person are available. Travel duration is 11h 35m
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Pluss Chile10h 45m001:50La SerenaCentral Coach Station12:35AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Coach Station, La Serena (Chile) at 25/08/2026 01:50:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 25/08/2026 12:35:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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Cikbus Elité11h 45m018:00La SerenaCentral Coach Station05:45AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 25/08/2026 18:00:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 26/08/2026 05:45:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 11h 45m
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Pullman San Andres12h 10m002:30La SerenaCentral Coach Station14:40AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 25/08/2026 02:30:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 25/08/2026 14:40:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
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Cormar Bus11h 50m005:55La SerenaCentral Coach Station17:45AntofagastaCamus Coach Station0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 25/08/2026 05:55:00 to Camus Coach Station, Antofagasta (Chile) arriving at 25/08/2026 17:45:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 11h 50m
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Sky Airline20h 58m011:04La Florida, La Serena AirportLa Florida, La Serena Airport08:02Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 25/08/2026 11:04:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 26/08/2026 08:02:00. 50 Economy ticket for £35 per person are available. Travel duration is 20h 58m
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Sky Airline15h 0m017:02La Florida, La Serena AirportLa Florida, La Serena Airport08:02Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 25/08/2026 17:02:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 26/08/2026 08:02:00. 50 Economy ticket for £35 per person are available. Travel duration is 15h 0m
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LAN Airlines17h 21m014:50La Florida, La Serena AirportLa Florida, La Serena Airport08:11Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 25/08/2026 14:50:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 26/08/2026 08:11:00. 50 Economy ticket for £38 per person are available. Travel duration is 17h 21m
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LAN Airlines17h 12m014:50La Florida, La Serena AirportLa Florida, La Serena Airport08:02Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 25/08/2026 14:50:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 26/08/2026 08:02:00. 50 Economy ticket for £38 per person are available. Travel duration is 17h 12m
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LATAM Brasil17h 12m014:50La Florida, La Serena AirportLa Florida, La Serena Airport08:02Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 25/08/2026 14:50:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 26/08/2026 08:02:00. 50 Economy ticket for £39 per person are available. Travel duration is 17h 12m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Andimar11h 35m014:00La SerenaCentral Coach Station01:35AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Andimar goes from Central Coach Station, La Serena (Chile) at 26/08/2026 14:00:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 27/08/2026 01:35:00. 50 Economy ticket for £22 per person are available. Travel duration is 11h 35m
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FlixBus11h 55m022:15La SerenaCentral Coach Station10:10AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Coach Station, La Serena (Chile) at 26/08/2026 22:15:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 27/08/2026 10:10:00. 50 Economy ticket for £23 per person are available. Travel duration is 11h 55m
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Cormar Bus11h 50m014:20La SerenaCentral Coach Station02:10AntofagastaCamus Coach Station0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 26/08/2026 14:20:00 to Camus Coach Station, Antofagasta (Chile) arriving at 27/08/2026 02:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 11h 50m
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Pullman San Andres12h 10m002:30La SerenaCentral Coach Station14:40AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 26/08/2026 02:30:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 26/08/2026 14:40:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
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Cikbus Elité11h 45m005:15La SerenaCentral Coach Station17:00AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 26/08/2026 05:15:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 26/08/2026 17:00:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 11h 45m
Cheapest Buses Wednesday
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Andimar11h 35m014:00La SerenaCentral Coach Station01:35AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Andimar goes from Central Coach Station, La Serena (Chile) at 27/08/2026 14:00:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 28/08/2026 01:35:00. 50 Economy ticket for £22 per person are available. Travel duration is 11h 35m
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Cormar Bus11h 50m005:55La SerenaCentral Coach Station17:45AntofagastaCamus Coach Station0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 27/08/2026 05:55:00 to Camus Coach Station, Antofagasta (Chile) arriving at 27/08/2026 17:45:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 11h 50m
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Pullman San Andres12h 10m002:30La SerenaCentral Coach Station14:40AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 27/08/2026 02:30:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 27/08/2026 14:40:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
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Cikbus Elité11h 45m005:15La SerenaCentral Coach Station17:00AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 27/08/2026 05:15:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 27/08/2026 17:00:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 11h 45m
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Pullman Bus12h 20m014:30La SerenaEl Sto, 106002:50AntofagastaCamus Coach Station0First ClassA Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 27/08/2026 14:30:00 to Camus Coach Station, Antofagasta (Chile) arriving at 28/08/2026 02:50:00. 50 First Class ticket for £28 per person are available. Travel duration is 12h 20m
Cheapest Buses Thursday
What are the fastest trips from La Serena to Antofagasta?
You can get to Antofagasta from La Serena in just 1h 19m with a Flight from Sky Airline. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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LATAM Brasil1h 24m016:27La Florida, La Serena AirportLa Florida, La Serena Airport17:51Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 21/08/2026 16:27:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 21/08/2026 17:51:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 24m
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LAN Airlines1h 24m016:27La Florida, La Serena AirportLa Florida, La Serena Airport17:51Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 21/08/2026 16:27:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 21/08/2026 17:51:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 24m
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LATAM Brasil6h 59m009:45La Florida, La Serena AirportLa Florida, La Serena Airport16:44Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 21/08/2026 09:45:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 21/08/2026 16:44:00. 50 Economy ticket for £148 per person are available. Travel duration is 6h 59m
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LAN Airlines7h 30m009:45La Florida, La Serena AirportLa Florida, La Serena Airport17:15Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 21/08/2026 09:45:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 21/08/2026 17:15:00. 50 Economy ticket for £144 per person are available. Travel duration is 7h 30m
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Sky Airline15h 3m019:59La Florida, La Serena AirportLa Florida, La Serena Airport11:02Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 21/08/2026 19:59:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 22/08/2026 11:02:00. 50 Economy ticket for £142 per person are available. Travel duration is 15h 3m
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Pluss Chile10h 45m001:50La SerenaCentral Coach Station12:35AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Coach Station, La Serena (Chile) at 21/08/2026 01:50:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 21/08/2026 12:35:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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Cikbus Elité11h 45m005:15La SerenaCentral Coach Station17:00AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 21/08/2026 05:15:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 21/08/2026 17:00:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 11h 45m
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Pullman Bus11h 50m021:00La SerenaEl Sto, 106008:50AntofagastaCamus Coach Station0First ClassA Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 21/08/2026 21:00:00 to Camus Coach Station, Antofagasta (Chile) arriving at 22/08/2026 08:50:00. 50 First Class ticket for £19 per person are available. Travel duration is 11h 50m
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Cormar Bus11h 50m014:20La SerenaCentral Coach Station02:10AntofagastaCamus Coach Station0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 21/08/2026 14:20:00 to Camus Coach Station, Antofagasta (Chile) arriving at 22/08/2026 02:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 11h 50m
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Pullman San Andres12h 10m022:00La SerenaCentral Coach Station10:10AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 21/08/2026 22:00:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 22/08/2026 10:10:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
Fastest Flights Friday
Fastest Buses Friday
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LAN Airlines11h 23m020:17La Florida, La Serena AirportLa Florida, La Serena Airport07:40Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 22/08/2026 20:17:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 23/08/2026 07:40:00. 50 Economy ticket for £132 per person are available. Travel duration is 11h 23m
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LATAM Brasil11h 23m020:17La Florida, La Serena AirportLa Florida, La Serena Airport07:40Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 22/08/2026 20:17:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 23/08/2026 07:40:00. 50 Economy ticket for £141 per person are available. Travel duration is 11h 23m
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Sky Airline18h 26m013:14La Florida, La Serena AirportLa Florida, La Serena Airport07:40Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 22/08/2026 13:14:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 23/08/2026 07:40:00. 50 Economy ticket for £130 per person are available. Travel duration is 18h 26m
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JetSmart20h 49m010:51La Florida, La Serena AirportLa Florida, La Serena Airport07:40Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 22/08/2026 10:51:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 23/08/2026 07:40:00. 50 Economy ticket for £115 per person are available. Travel duration is 20h 49m
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Andimar11h 35m014:00La SerenaCentral Coach Station01:35AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Andimar goes from Central Coach Station, La Serena (Chile) at 22/08/2026 14:00:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 23/08/2026 01:35:00. 50 Economy ticket for £24 per person are available. Travel duration is 11h 35m
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Cikbus Elité11h 45m005:15La SerenaCentral Coach Station17:00AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 22/08/2026 05:15:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 22/08/2026 17:00:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 11h 45m
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Cormar Bus11h 50m005:55La SerenaCentral Coach Station17:45AntofagastaCamus Coach Station0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 22/08/2026 05:55:00 to Camus Coach Station, Antofagasta (Chile) arriving at 22/08/2026 17:45:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 11h 50m
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Pullman Bus11h 50m021:00La SerenaEl Sto, 106008:50AntofagastaCamus Coach Station0First ClassA Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 22/08/2026 21:00:00 to Camus Coach Station, Antofagasta (Chile) arriving at 23/08/2026 08:50:00. 50 First Class ticket for £26 per person are available. Travel duration is 11h 50m
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Pullman San Andres12h 10m002:30La SerenaCentral Coach Station14:40AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 22/08/2026 02:30:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 22/08/2026 14:40:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
Fastest Flights Saturday
Fastest Buses Saturday
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Sky Airline1h 19m012:21La Florida, La Serena AirportLa Florida, La Serena Airport13:40Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 23/08/2026 12:21:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 23/08/2026 13:40:00. 50 Economy ticket for £110 per person are available. Travel duration is 1h 19m
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JetSmart1h 22m019:55La Florida, La Serena AirportLa Florida, La Serena Airport21:17Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 23/08/2026 19:55:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 23/08/2026 21:17:00. 50 Economy ticket for £230 per person are available. Travel duration is 1h 22m
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LAN Airlines1h 24m019:33La Florida, La Serena AirportLa Florida, La Serena Airport20:57Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 23/08/2026 19:33:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 23/08/2026 20:57:00. 50 Economy ticket for £27 per person are available. Travel duration is 1h 24m
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Pluss Chile10h 45m001:50La SerenaCentral Coach Station12:35AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Coach Station, La Serena (Chile) at 23/08/2026 01:50:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 23/08/2026 12:35:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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Andimar11h 35m014:00La SerenaCentral Coach Station01:35AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Andimar goes from Central Coach Station, La Serena (Chile) at 23/08/2026 14:00:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 24/08/2026 01:35:00. 50 Economy ticket for £24 per person are available. Travel duration is 11h 35m
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Cormar Bus11h 50m005:55La SerenaCentral Coach Station17:45AntofagastaCamus Coach Station0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 23/08/2026 05:55:00 to Camus Coach Station, Antofagasta (Chile) arriving at 23/08/2026 17:45:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 11h 50m
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FlixBus11h 55m022:15La SerenaCentral Coach Station10:10AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Coach Station, La Serena (Chile) at 23/08/2026 22:15:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 24/08/2026 10:10:00. 50 Economy ticket for £25 per person are available. Travel duration is 11h 55m
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Pullman San Andres12h 10m002:30La SerenaCentral Coach Station14:40AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 23/08/2026 02:30:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 23/08/2026 14:40:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
Fastest Flights Sunday
Fastest Buses Sunday
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LAN Airlines1h 23m009:59La Florida, La Serena AirportLa Florida, La Serena Airport11:22Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 24/08/2026 09:59:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 24/08/2026 11:22:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 23m
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JetSmart12h 37m020:35La Florida, La Serena AirportLa Florida, La Serena Airport09:12Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 24/08/2026 20:35:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 25/08/2026 09:12:00. 50 Economy ticket for £152 per person are available. Travel duration is 12h 37m
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JetSmart19h 44m010:51La Florida, La Serena AirportLa Florida, La Serena Airport06:35Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 24/08/2026 10:51:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 25/08/2026 06:35:00. 50 Economy ticket for £157 per person are available. Travel duration is 19h 44m
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LAN Airlines23h 7m022:32La Florida, La Serena AirportLa Florida, La Serena Airport21:39Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 24/08/2026 22:32:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 25/08/2026 21:39:00. 50 Economy ticket for £120 per person are available. Travel duration is 23h 7m
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LATAM Brasil23h 7m022:32La Florida, La Serena AirportLa Florida, La Serena Airport21:39Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 24/08/2026 22:32:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 25/08/2026 21:39:00. 50 Economy ticket for £128 per person are available. Travel duration is 23h 7m
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Pluss Chile10h 45m001:50La SerenaCentral Coach Station12:35AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Coach Station, La Serena (Chile) at 24/08/2026 01:50:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 24/08/2026 12:35:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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Andimar11h 35m017:10La SerenaCentral Coach Station04:45AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Andimar goes from Central Coach Station, La Serena (Chile) at 24/08/2026 17:10:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 25/08/2026 04:45:00. 50 Economy ticket for £22 per person are available. Travel duration is 11h 35m
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Cormar Bus11h 50m005:55La SerenaCentral Coach Station17:45AntofagastaCamus Coach Station0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 24/08/2026 05:55:00 to Camus Coach Station, Antofagasta (Chile) arriving at 24/08/2026 17:45:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 11h 50m
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FlixBus11h 55m022:15La SerenaCentral Coach Station10:10AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Coach Station, La Serena (Chile) at 24/08/2026 22:15:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 25/08/2026 10:10:00. 50 Economy ticket for £25 per person are available. Travel duration is 11h 55m
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Pullman San Andres12h 10m002:30La SerenaCentral Coach Station14:40AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 24/08/2026 02:30:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 24/08/2026 14:40:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
Fastest Flights Monday
Fastest Buses Monday
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Pluss Chile10h 45m001:50La SerenaCentral Coach Station12:35AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pluss Chile goes from Central Coach Station, La Serena (Chile) at 25/08/2026 01:50:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 25/08/2026 12:35:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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Andimar11h 35m017:10La SerenaCentral Coach Station04:45AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Andimar goes from Central Coach Station, La Serena (Chile) at 25/08/2026 17:10:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 26/08/2026 04:45:00. 50 Economy ticket for £22 per person are available. Travel duration is 11h 35m
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Cikbus Elité11h 45m018:00La SerenaCentral Coach Station05:45AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 25/08/2026 18:00:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 26/08/2026 05:45:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 11h 45m
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Cormar Bus11h 50m005:55La SerenaCentral Coach Station17:45AntofagastaCamus Coach Station0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 25/08/2026 05:55:00 to Camus Coach Station, Antofagasta (Chile) arriving at 25/08/2026 17:45:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 11h 50m
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Pullman San Andres12h 10m002:30La SerenaCentral Coach Station14:40AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 25/08/2026 02:30:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 25/08/2026 14:40:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
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Sky Airline15h 0m017:02La Florida, La Serena AirportLa Florida, La Serena Airport08:02Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 25/08/2026 17:02:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 26/08/2026 08:02:00. 50 Economy ticket for £35 per person are available. Travel duration is 15h 0m
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LAN Airlines17h 12m014:50La Florida, La Serena AirportLa Florida, La Serena Airport08:02Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 25/08/2026 14:50:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 26/08/2026 08:02:00. 50 Economy ticket for £38 per person are available. Travel duration is 17h 12m
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LATAM Brasil17h 12m014:50La Florida, La Serena AirportLa Florida, La Serena Airport08:02Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LATAM Brasil goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 25/08/2026 14:50:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 26/08/2026 08:02:00. 50 Economy ticket for £39 per person are available. Travel duration is 17h 12m
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LAN Airlines17h 21m014:50La Florida, La Serena AirportLa Florida, La Serena Airport08:11Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 25/08/2026 14:50:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 26/08/2026 08:11:00. 50 Economy ticket for £38 per person are available. Travel duration is 17h 21m
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Sky Airline20h 58m011:04La Florida, La Serena AirportLa Florida, La Serena Airport08:02Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 25/08/2026 11:04:00 to Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) arriving at 26/08/2026 08:02:00. 50 Economy ticket for £35 per person are available. Travel duration is 20h 58m
Fastest Buses Tuesday
Fastest Flights Tuesday
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Andimar11h 35m014:00La SerenaCentral Coach Station01:35AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Andimar goes from Central Coach Station, La Serena (Chile) at 26/08/2026 14:00:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 27/08/2026 01:35:00. 50 Economy ticket for £22 per person are available. Travel duration is 11h 35m
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Cikbus Elité11h 45m005:15La SerenaCentral Coach Station17:00AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 26/08/2026 05:15:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 26/08/2026 17:00:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 11h 45m
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Cormar Bus11h 50m014:20La SerenaCentral Coach Station02:10AntofagastaCamus Coach Station0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 26/08/2026 14:20:00 to Camus Coach Station, Antofagasta (Chile) arriving at 27/08/2026 02:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 11h 50m
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FlixBus11h 55m022:15La SerenaCentral Coach Station10:10AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from FlixBus goes from Central Coach Station, La Serena (Chile) at 26/08/2026 22:15:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 27/08/2026 10:10:00. 50 Economy ticket for £23 per person are available. Travel duration is 11h 55m
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Pullman San Andres12h 10m002:30La SerenaCentral Coach Station14:40AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 26/08/2026 02:30:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 26/08/2026 14:40:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
Fastest Buses Wednesday
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Andimar11h 35m014:00La SerenaCentral Coach Station01:35AntofagastaCarlos Oviedo Cavada Bus Station0EconomyA Bus from Andimar goes from Central Coach Station, La Serena (Chile) at 27/08/2026 14:00:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 28/08/2026 01:35:00. 50 Economy ticket for £22 per person are available. Travel duration is 11h 35m
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Cikbus Elité11h 45m005:15La SerenaCentral Coach Station17:00AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 27/08/2026 05:15:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 27/08/2026 17:00:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 11h 45m
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Cormar Bus11h 50m005:55La SerenaCentral Coach Station17:45AntofagastaCamus Coach Station0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 27/08/2026 05:55:00 to Camus Coach Station, Antofagasta (Chile) arriving at 27/08/2026 17:45:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 11h 50m
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Pullman San Andres12h 10m002:30La SerenaCentral Coach Station14:40AntofagastaCarlos Oviedo Cavada Bus Station0Premium EconomyA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 27/08/2026 02:30:00 to Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) arriving at 27/08/2026 14:40:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
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Pullman Bus12h 20m014:30La SerenaEl Sto, 106002:50AntofagastaCamus Coach Station0First ClassA Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 27/08/2026 14:30:00 to Camus Coach Station, Antofagasta (Chile) arriving at 28/08/2026 02:50:00. 50 First Class ticket for £28 per person are available. Travel duration is 12h 20m
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from La Serena to Antofagasta
What are the most popular stations in La Serena and Antofagasta?
In La Serena, you will usually depart from Central Coach Station, El Sto, 1060 or Avda. Fco de Aguirre Station, while in Antofagasta you will be arriving at Carlos Oviedo Cavada Bus Station, Maipú or Camus Coach Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Antofagasta from La Serena? With 8 connections between 9 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between La Serena and Antofagasta, you can pay as low as £19 with a Bus from Pullman Bus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Sky Airline: you will get to Antofagasta in just 1h 19m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting La Serena and Antofagasta are LAN Airlines, Cormar Bus and Pullman San Andres, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in La Serena and Antofagasta is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from La Florida, La Serena Airport or to La Negra, and look at flights from La Florida, La Serena Airport, and landing at Andrés Sabella Gálvez, Antofagasta Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from La Serena to Antofagasta?
The most popular companies between La Serena and Antofagasta, are LAN Airlines, Cormar Bus and Pullman San Andres. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Cormar Bus, Pullman San Andres, Andimar and 4 more.
Airlines: LAN Airlines, Sky Airline, JetSmart and 1 more.
All you need to know when you travel from La Serena to Antofagasta
Check all information on comfort and services on all modes of transports from La Serena to Antofagasta. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from La Serena to Antofagasta
How can I reach Antofagasta from La Serena?
Every day, there are on average 8 connections between Flight and Bus, with which you can get to Antofagasta from La Serena.
How far is Antofagasta from La Serena?
The distance between La Serena and Antofagasta is 700.4 km.
What is the most ecofriendly mode of transport between La Serena and Antofagasta?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 119 kgs, and a flight 172 kgs.
What is the cheapest mode of transport from La Serena to Antofagasta?
You can get to Antofagasta with just £19 by taking a Bus from Pullman Bus.
What is the fastest way to get from La Serena to Antofagasta?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Antofagasta in just 1h 19m with a Flight from Sky Airline.
More routes to La Serena and to Antofagasta
Looking for more options? Here you can see the most popular routes to La Serena and to Antofagasta. Simply click on a connection, and you’ll find all the details about the route!
