Which bus from Brussels to Lyon is the best?
Check the bus schedule for Brussels to Lyon. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or BlaBlaCar Bus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 10h 10m | 19:05 | Brussels | Midi Bus Station | 05:15 | Lyon | Perrache Bus Stop | Economy | £21 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 05/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 05:15:00. 50 Economy ticket for £21 per person are available. Travel duration is 10h 10m
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| BlaBlaCar Bus | 11h 25m | 07:20 | Brussels | Midi Bus Station | 18:45 | Lyon | Perrache Bus Stop | Economy | £23 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 05/12/2025 07:20:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 18:45:00. 50 Economy ticket for £23 per person are available. Travel duration is 11h 25m
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| BlaBlaCar Bus | 10h 15m | 19:05 | Brussels | Midi Bus Station | 05:20 | Lyon | Perrache Bus Stop | Economy | £24 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 05/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 05:20:00. 50 Economy ticket for £24 per person are available. Travel duration is 10h 15m
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| FlixBus | 10h 30m | 20:15 | Brussels | Midi Bus Station | 06:45 | Lyon | Perrache Bus Stop | Economy | £38 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 05/12/2025 20:15:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 06:45:00. 50 Economy ticket for £38 per person are available. Travel duration is 10h 30m
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| FlixBus | 13h 15m | 01:30 | Brussels | Midi Bus Station | 14:45 | Lyon | Perrache Bus Stop | Economy | £39 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 05/12/2025 01:30:00 to Perrache Bus Stop, Lyon (France) arriving at 05/12/2025 14:45:00. 50 Economy ticket for £39 per person are available. Travel duration is 13h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 11h 25m | 07:20 | Brussels | Midi Bus Station | 18:45 | Lyon | Perrache Bus Stop | Economy | £19 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 06/12/2025 07:20:00 to Perrache Bus Stop, Lyon (France) arriving at 06/12/2025 18:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 11h 25m
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| BlaBlaCar Bus | 10h 45m | 13:30 | Brussels | Midi Bus Station | 00:15 | Lyon | Perrache Bus Stop | Economy | £19 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 06/12/2025 13:30:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 00:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 45m
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| BlaBlaCar Bus | 10h 10m | 19:05 | Brussels | Midi Bus Station | 05:15 | Lyon | Perrache Bus Stop | Economy | £21 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 06/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 05:15:00. 50 Economy ticket for £21 per person are available. Travel duration is 10h 10m
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| FlixBus | 10h 55m | 14:15 | Brussels | Midi Bus Station | 01:10 | Lyon | Perrache Bus Stop | Economy | £28 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 06/12/2025 14:15:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 01:10:00. 50 Economy ticket for £28 per person are available. Travel duration is 10h 55m
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| FlixBus | 10h 40m | 16:40 | Brussels | Midi Bus Station | 03:20 | Lyon | Perrache Bus Stop | Economy | £28 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 06/12/2025 16:40:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 03:20:00. 50 Economy ticket for £28 per person are available. Travel duration is 10h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 11h 25m | 07:20 | Brussels | Midi Bus Station | 18:45 | Lyon | Perrache Bus Stop | Economy | £27 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 07/12/2025 07:20:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 18:45:00. 50 Economy ticket for £27 per person are available. Travel duration is 11h 25m
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| BlaBlaCar Bus | 11h 24m | 03:11 | Brussels | Midi Bus Station | 14:35 | Lyon | Perrache Train Station | Economy | £30 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 07/12/2025 03:11:00 to Perrache Train Station, Lyon (France) arriving at 07/12/2025 14:35:00. 50 Economy ticket for £30 per person are available. Travel duration is 11h 24m
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| FlixBus | 10h 30m | 20:15 | Brussels | Midi Bus Station | 06:45 | Lyon | Perrache Bus Stop | Economy | £36 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 07/12/2025 20:15:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 06:45:00. 50 Economy ticket for £36 per person are available. Travel duration is 10h 30m
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| FlixBus | 12h 20m | 22:55 | Brussels | North Station | 11:15 | Lyon | Perrache Bus Stop | Economy | £37 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 07/12/2025 22:55:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 11:15:00. 50 Economy ticket for £37 per person are available. Travel duration is 12h 20m
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| BlaBlaCar Bus | 10h 45m | 13:30 | Brussels | Midi Bus Station | 00:15 | Lyon | Perrache Bus Stop | Economy | £38 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 07/12/2025 13:30:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 00:15:00. 50 Economy ticket for £38 per person are available. Travel duration is 10h 45m
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Save more than 22%11h 25mBrussels2 km07:20Saint-GillesBarrière18:45LyonPerrache Bus Stop0 kmEconomyA Bus from goes from Barrière, Saint-Gilles (Belgium) at 07/12/2025 07:20:00 to Perrache Bus Stop, Lyon (France) arriving at 07/12/2025 18:45:00. 50 Economy ticket for £21 per person are available. Travel duration is 11h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 11h 25m | 07:20 | Brussels | Midi Bus Station | 18:45 | Lyon | Perrache Bus Stop | Economy | £19 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 07:20:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 18:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 11h 25m
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| BlaBlaCar Bus | 10h 45m | 13:30 | Brussels | Midi Bus Station | 00:15 | Lyon | Perrache Bus Stop | Economy | £19 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 13:30:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 00:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 45m
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| BlaBlaCar Bus | 10h 10m | 19:05 | Brussels | Midi Bus Station | 05:15 | Lyon | Perrache Bus Stop | Economy | £19 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 05:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 10m
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| FlixBus | 10h 30m | 20:15 | Brussels | Midi Bus Station | 06:45 | Lyon | Perrache Bus Stop | Economy | £24 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 20:15:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 06:45:00. 50 Economy ticket for £24 per person are available. Travel duration is 10h 30m
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| FlixBus | 11h 45m | 18:15 | Brussels | North Station | 06:00 | Lyon | Perrache Bus Stop | Economy | £25 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 08/12/2025 18:15:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 06:00:00. 50 Economy ticket for £25 per person are available. Travel duration is 11h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 11h 50m | 12:00 | Brussels | North Station | 23:50 | Lyon | Perrache Bus Stop | Economy | £25 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 12:00:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 23:50:00. 50 Economy ticket for £25 per person are available. Travel duration is 11h 50m
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| FlixBus | 11h 5m | 16:15 | Brussels | North Station | 03:20 | Lyon | Perrache Bus Stop | Economy | £25 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 16:15:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 03:20:00. 50 Economy ticket for £25 per person are available. Travel duration is 11h 5m
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| FlixBus | 11h 45m | 18:15 | Brussels | North Station | 06:00 | Lyon | Perrache Bus Stop | Economy | £25 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 18:15:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 06:00:00. 50 Economy ticket for £25 per person are available. Travel duration is 11h 45m
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| FlixBus | 13h 15m | 01:30 | Brussels | Midi Bus Station | 14:45 | Lyon | Perrache Bus Stop | Economy | £26 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 09/12/2025 01:30:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 14:45:00. 50 Economy ticket for £26 per person are available. Travel duration is 13h 15m
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| FlixBus | 11h 30m | 13:40 | Brussels | Midi Bus Station | 01:10 | Lyon | Perrache Bus Stop | Economy | £26 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 09/12/2025 13:40:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 01:10:00. 50 Economy ticket for £26 per person are available. Travel duration is 11h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 10h 30m | 20:15 | Brussels | Midi Bus Station | 06:45 | Lyon | Perrache Bus Stop | Economy | £24 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 20:15:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 06:45:00. 50 Economy ticket for £24 per person are available. Travel duration is 10h 30m
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| FlixBus | 12h 20m | 15:00 | Brussels | North Station | 03:20 | Lyon | Perrache Bus Stop | Economy | £25 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 10/12/2025 15:00:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 03:20:00. 50 Economy ticket for £25 per person are available. Travel duration is 12h 20m
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| FlixBus | 11h 30m | 13:40 | Brussels | Midi Bus Station | 01:10 | Lyon | Perrache Bus Stop | Economy | £26 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 13:40:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 01:10:00. 50 Economy ticket for £26 per person are available. Travel duration is 11h 30m
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| FlixBus | 13h 15m | 01:30 | Brussels | Midi Bus Station | 14:45 | Lyon | Perrache Bus Stop | Economy | £27 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 01:30:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 14:45:00. 50 Economy ticket for £27 per person are available. Travel duration is 13h 15m
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| FlixBus | 12h 10m | 15:10 | Brussels | Midi Bus Station | 03:20 | Lyon | Perrache Bus Stop | Economy | £28 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 15:10:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 03:20:00. 50 Economy ticket for £28 per person are available. Travel duration is 12h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 12h 5m | 06:40 | Brussels | Midi Bus Station | 18:45 | Lyon | Perrache Bus Stop | Economy | £19 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 11/12/2025 06:40:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 18:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 12h 5m
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| BlaBlaCar Bus | 10h 45m | 13:30 | Brussels | Midi Bus Station | 00:15 | Lyon | Perrache Train Station | Economy | £19 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 11/12/2025 13:30:00 to Perrache Train Station, Lyon (France) arriving at 12/12/2025 00:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 45m
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| BlaBlaCar Bus | 10h 5m | 17:55 | Brussels | Midi Bus Station | 04:00 | Lyon | Perrache Bus Stop | Economy | £19 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 11/12/2025 17:55:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 04:00:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 5m
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| FlixBus | 11h 50m | 15:30 | Brussels | North Station | 03:20 | Lyon | Perrache Bus Stop | Economy | £25 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 15:30:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 03:20:00. 50 Economy ticket for £25 per person are available. Travel duration is 11h 50m
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| FlixBus | 11h 45m | 18:15 | Brussels | North Station | 06:00 | Lyon | Perrache Bus Stop | Economy | £25 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 18:15:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 06:00:00. 50 Economy ticket for £25 per person are available. Travel duration is 11h 45m
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Best Price Offer: The price for the cheapest coach from Brussels to Lyon is £19 on 06/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Brussels and Lyon?
All facts for Brussels to Lyon bus at a glance
Compare all coach operators like FlixBus and BlaBlaCar Bus that travel daily 21 times by bus from Brussels to Lyon in one click. Book your Brussels to Lyon bus ticket starting from £19!
| Cheapest Bus | £19 |
| Fastest Bus | 10h 5m |
| Earliest Coach | 01:30 |
| Latest Coach | 22:05 |
| Daily Bus Connections | 21 Ø |
| Distance | 567.4 km |
| Coach Companies | FlixBus and BlaBlaCar Bus |
What are the cheapest coach tickets from Brussels to Lyon?
Every day, 21 buses from 2 coach companies leave Brussels for Lyon. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Brussels to Lyon
How to save money travelling from Brussels to Lyon
Book the ticket from Brussels to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Brussels to Lyon, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Brussels to Lyon are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
What are the most popular bus companies from Brussels to Lyon?
BlaBlaCar Bus from Brussels to Lyon
Here you will find the key facts about the BlaBlaCar Bus bus route Brussels to Lyon:
| Cheapest Price | £19 |
| Fastest Coach | 10h 5m |
| Earliest Coach | 03:11 |
| Last Coach | 19:05 |
| Daily Connections | 11 Ø |
| Found on | 04/12/2025 |
All bus stations and stops in Brussels and Lyon
Here is a map with all coach stations in Brussels and Lyon. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Brussels to Lyon
FAQs for Brussels to Lyon bus
How much does a Brussels Lyon coach trip cost?
How much could I save by comparing buses from Brussels to Lyon?
How many connections are available for the Brussels Lyon route on average every day?
How long does a bus to Lyon from Brussels take?
What time is the first bus from Brussels to Lyon?
What time is the last coach from Brussels to Lyon?
Which bus companies serve the Brussels Lyon route?
Is there a direct bus between Brussels and Lyon?
What can I take with me on the bus to Lyon from Brussels?
What equipment is available for the Brussels Lyon bus route?
Available seat classes which are offered on the bus route Brussels to Lyon
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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