Which bus from Brussels to Lyon is the best?
Check the bus schedule for Brussels to Lyon. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or BlaBlaCar Bus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 10h 30m | 14:20 | Brussels | Midi Bus Station | 00:50 | Lyon | Perrache Train Station | Economy | £21 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 04/05/2026 14:20:00 to Perrache Train Station, Lyon (France) arriving at 05/05/2026 00:50:00. 50 Economy ticket for £21 per person are available. Travel duration is 10h 30m
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| BlaBlaCar Bus | 10h 10m | 17:55 | Brussels | Midi Bus Station | 04:05 | Lyon | Perrache Train Station | Economy | £21 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 04/05/2026 17:55:00 to Perrache Train Station, Lyon (France) arriving at 05/05/2026 04:05:00. 50 Economy ticket for £21 per person are available. Travel duration is 10h 10m
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| BlaBlaCar Bus | 10h 10m | 18:20 | Brussels | Midi Bus Station | 04:30 | Lyon | Perrache Train Station | Economy | £21 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 04/05/2026 18:20:00 to Perrache Train Station, Lyon (France) arriving at 05/05/2026 04:30:00. 50 Economy ticket for £21 per person are available. Travel duration is 10h 10m
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| FlixBus | 10h 35m | 20:15 | Brussels | Midi Bus Station | 06:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £52 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 04/05/2026 20:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 05/05/2026 06:50:00. 50 Economy ticket for £52 per person are available. Travel duration is 10h 35m
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| FlixBus | 11h 45m | 18:15 | Brussels | North Station | 06:00 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £59 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 04/05/2026 18:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 05/05/2026 06:00:00. 50 Economy ticket for £59 per person are available. Travel duration is 11h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 10h 15m | 19:05 | Brussels | Midi Bus Station | 05:20 | Lyon | Perrache Train Station | Economy | £21 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 05/05/2026 19:05:00 to Perrache Train Station, Lyon (France) arriving at 06/05/2026 05:20:00. 50 Economy ticket for £21 per person are available. Travel duration is 10h 15m
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| BlaBlaCar Bus | 10h 20m | 19:05 | Brussels | Midi Bus Station | 05:25 | Lyon | Perrache Train Station | Economy | £21 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 05/05/2026 19:05:00 to Perrache Train Station, Lyon (France) arriving at 06/05/2026 05:25:00. 50 Economy ticket for £21 per person are available. Travel duration is 10h 20m
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| BlaBlaCar Bus | 12h 10m | 13:30 | Brussels | Midi Bus Station | 01:40 | Lyon | Perrache Train Station | Economy | £22 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 05/05/2026 13:30:00 to Perrache Train Station, Lyon (France) arriving at 06/05/2026 01:40:00. 50 Economy ticket for £22 per person are available. Travel duration is 12h 10m
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| FlixBus | 10h 35m | 20:15 | Brussels | Midi Bus Station | 06:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £50 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 05/05/2026 20:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 06/05/2026 06:50:00. 50 Economy ticket for £50 per person are available. Travel duration is 10h 35m
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| FlixBus | 14h 0m | 00:45 | Brussels | North Station | 14:45 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £55 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 05/05/2026 00:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 05/05/2026 14:45:00. 50 Economy ticket for £55 per person are available. Travel duration is 14h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 10h 10m | 17:55 | Brussels | Midi Bus Station | 04:05 | Lyon | Perrache Train Station | Economy | £22 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 06/05/2026 17:55:00 to Perrache Train Station, Lyon (France) arriving at 07/05/2026 04:05:00. 50 Economy ticket for £22 per person are available. Travel duration is 10h 10m
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| BlaBlaCar Bus | 10h 20m | 19:05 | Brussels | Midi Bus Station | 05:25 | Lyon | Perrache Train Station | Economy | £24 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 06/05/2026 19:05:00 to Perrache Train Station, Lyon (France) arriving at 07/05/2026 05:25:00. 50 Economy ticket for £24 per person are available. Travel duration is 10h 20m
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| BlaBlaCar Bus | 10h 15m | 19:05 | Brussels | Midi Bus Station | 05:20 | Lyon | Perrache Train Station | Economy | £24 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 06/05/2026 19:05:00 to Perrache Train Station, Lyon (France) arriving at 07/05/2026 05:20:00. 50 Economy ticket for £24 per person are available. Travel duration is 10h 15m
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| FlixBus | 10h 35m | 20:15 | Brussels | Midi Bus Station | 06:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £47 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 06/05/2026 20:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 07/05/2026 06:50:00. 50 Economy ticket for £47 per person are available. Travel duration is 10h 35m
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| FlixBus | 12h 10m | 00:45 | Brussels | North Station | 12:55 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £52 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 06/05/2026 00:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 06/05/2026 12:55:00. 50 Economy ticket for £52 per person are available. Travel duration is 12h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 11h 30m | 07:20 | Brussels | Midi Bus Station | 18:50 | Lyon | Perrache Train Station | Economy | £33 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 07/05/2026 07:20:00 to Perrache Train Station, Lyon (France) arriving at 07/05/2026 18:50:00. 50 Economy ticket for £33 per person are available. Travel duration is 11h 30m
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| BlaBlaCar Bus | 10h 50m | 13:30 | Brussels | Midi Bus Station | 00:20 | Lyon | Perrache Train Station | Economy | £33 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 07/05/2026 13:30:00 to Perrache Train Station, Lyon (France) arriving at 08/05/2026 00:20:00. 50 Economy ticket for £33 per person are available. Travel duration is 10h 50m
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| BlaBlaCar Bus | 10h 55m | 17:10 | Brussels | North Station | 04:05 | Lyon | Perrache Train Station | Economy | £39 |
A Bus from BlaBlaCar Bus goes from North Station, Brussels (Belgium) at 07/05/2026 17:10:00 to Perrache Train Station, Lyon (France) arriving at 08/05/2026 04:05:00. 50 Economy ticket for £39 per person are available. Travel duration is 10h 55m
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| FlixBus | 12h 10m | 16:40 | Brussels | North Station | 04:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £58 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 07/05/2026 16:40:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/05/2026 04:50:00. 50 Economy ticket for £58 per person are available. Travel duration is 12h 10m
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| FlixBus | 11h 10m | 15:10 | Brussels | Midi Bus Station | 02:20 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £58 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 07/05/2026 15:10:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/05/2026 02:20:00. 50 Economy ticket for £58 per person are available. Travel duration is 11h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 10h 35m | 16:55 | Brussels | Midi Bus Station | 03:30 | Lyon | Perrache Train Station | Economy | £21 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 08/05/2026 16:55:00 to Perrache Train Station, Lyon (France) arriving at 09/05/2026 03:30:00. 50 Economy ticket for £21 per person are available. Travel duration is 10h 35m
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| BlaBlaCar Bus | 10h 50m | 13:30 | Brussels | Midi Bus Station | 00:20 | Lyon | Perrache Train Station | Economy | £22 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 08/05/2026 13:30:00 to Perrache Train Station, Lyon (France) arriving at 09/05/2026 00:20:00. 50 Economy ticket for £22 per person are available. Travel duration is 10h 50m
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| BlaBlaCar Bus | 10h 10m | 17:55 | Brussels | Midi Bus Station | 04:05 | Lyon | Perrache Train Station | Economy | £22 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 08/05/2026 17:55:00 to Perrache Train Station, Lyon (France) arriving at 09/05/2026 04:05:00. 50 Economy ticket for £22 per person are available. Travel duration is 10h 10m
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| FlixBus | 12h 10m | 00:45 | Brussels | North Station | 12:55 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £53 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 08/05/2026 00:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/05/2026 12:55:00. 50 Economy ticket for £53 per person are available. Travel duration is 12h 10m
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| FlixBus | 12h 35m | 07:00 | Brussels | North Station | 19:35 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £53 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 08/05/2026 07:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 08/05/2026 19:35:00. 50 Economy ticket for £53 per person are available. Travel duration is 12h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 10h 50m | 13:30 | Brussels | Midi Bus Station | 00:20 | Lyon | Perrache Train Station | Economy | £21 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 09/05/2026 13:30:00 to Perrache Train Station, Lyon (France) arriving at 10/05/2026 00:20:00. 50 Economy ticket for £21 per person are available. Travel duration is 10h 50m
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| BlaBlaCar Bus | 10h 35m | 16:55 | Brussels | Midi Bus Station | 03:30 | Lyon | Perrache Train Station | Economy | £21 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 09/05/2026 16:55:00 to Perrache Train Station, Lyon (France) arriving at 10/05/2026 03:30:00. 50 Economy ticket for £21 per person are available. Travel duration is 10h 35m
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| BlaBlaCar Bus | 10h 10m | 17:55 | Brussels | Midi Bus Station | 04:05 | Lyon | Perrache Train Station | Economy | £21 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 09/05/2026 17:55:00 to Perrache Train Station, Lyon (France) arriving at 10/05/2026 04:05:00. 50 Economy ticket for £21 per person are available. Travel duration is 10h 10m
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| FlixBus | 10h 35m | 20:15 | Brussels | Midi Bus Station | 06:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £56 |
A Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 09/05/2026 20:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/05/2026 06:50:00. 50 Economy ticket for £56 per person are available. Travel duration is 10h 35m
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| FlixBus | 10h 55m | 16:15 | Brussels | North Station | 03:10 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £61 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/05/2026 16:15:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/05/2026 03:10:00. 50 Economy ticket for £61 per person are available. Travel duration is 10h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BlaBlaCar Bus | 10h 55m | 17:10 | Brussels | North Station | 04:05 | Lyon | Perrache Train Station | Economy | £43 |
A Bus from BlaBlaCar Bus goes from North Station, Brussels (Belgium) at 10/05/2026 17:10:00 to Perrache Train Station, Lyon (France) arriving at 11/05/2026 04:05:00. 50 Economy ticket for £43 per person are available. Travel duration is 10h 55m
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| BlaBlaCar Bus | 11h 30m | 07:20 | Brussels | Midi Bus Station | 18:50 | Lyon | Perrache Train Station | Economy | £49 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 10/05/2026 07:20:00 to Perrache Train Station, Lyon (France) arriving at 10/05/2026 18:50:00. 50 Economy ticket for £49 per person are available. Travel duration is 11h 30m
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| BlaBlaCar Bus | 11h 50m | 12:00 | Brussels | Midi Bus Station | 23:50 | Lyon | Perrache Train Station | Economy | £53 |
A Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 10/05/2026 12:00:00 to Perrache Train Station, Lyon (France) arriving at 10/05/2026 23:50:00. 50 Economy ticket for £53 per person are available. Travel duration is 11h 50m
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| FlixBus | 11h 35m | 08:00 | Brussels | North Station | 19:35 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £72 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 10/05/2026 08:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/05/2026 19:35:00. 50 Economy ticket for £72 per person are available. Travel duration is 11h 35m
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| FlixBus | 12h 10m | 00:45 | Brussels | North Station | 12:55 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £73 |
A Bus from FlixBus goes from North Station, Brussels (Belgium) at 10/05/2026 00:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 10/05/2026 12:55:00. 50 Economy ticket for £73 per person are available. Travel duration is 12h 10m
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Best Price Offer: The price for the cheapest coach from Brussels to Lyon is £21 on 04/05/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Brussels and Lyon?
All facts for Brussels to Lyon bus at a glance
Compare all coach operators like FlixBus and BlaBlaCar Bus that travel daily 23 times by bus from Brussels to Lyon in one click. Book your Brussels to Lyon bus ticket starting from £21!
| Cheapest Bus | £21 |
| Fastest Bus | 10h 10m |
| Earliest Coach | 00:45 |
| Latest Coach | 22:55 |
| Daily Bus Connections | 23 Ø |
| Distance | 567.4 km |
| Coach Companies | FlixBus and BlaBlaCar Bus |
What are the cheapest coach tickets from Brussels to Lyon?
Every day, 23 buses from 2 coach companies leave Brussels for Lyon. Check the table below to find the cheapest prices for coach tickets for this route, starting from 04/05/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Brussels to Lyon
How to save money travelling from Brussels to Lyon
Book the ticket from Brussels to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Brussels to Lyon, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Brussels to Lyon are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Brussels and Lyon
Here is a map with all coach stations in Brussels and Lyon. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Brussels to Lyon
FAQs for Brussels to Lyon bus
How much does a Brussels Lyon coach trip cost?
How much could I save by comparing buses from Brussels to Lyon?
How many connections are available for the Brussels Lyon route on average every day?
How long does a bus to Lyon from Brussels take?
What time is the first bus from Brussels to Lyon?
What time is the last coach from Brussels to Lyon?
Which bus companies serve the Brussels Lyon route?
Is there a direct bus between Brussels and Lyon?
What can I take with me on the bus to Lyon from Brussels?
What equipment is available for the Brussels Lyon bus route?
How does CheckMyBus find the best coach deals from Brussels to Lyon?
How does CheckMyBus technology work for trips from Brussels to Lyon?
Available seat classes which are offered on the bus route Brussels to Lyon
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Brussels and to Lyon
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