What is the best way to travel from Brussels to Lyon?
Looking for a trip? Check and compare all the available Buses and Flights to Lyon from Brussels. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Lyon from Brussels?
You can reach Lyon with just £19 by taking a Bus from BlaBlaCar Bus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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BlaBlaCar Bus11h 25m007:20BrusselsMidi Bus Station18:45LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 07:20:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 18:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 11h 25m
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BlaBlaCar Bus10h 45m013:30BrusselsMidi Bus Station00:15LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 13:30:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 00:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 45m
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BlaBlaCar Bus10h 10m019:05BrusselsMidi Bus Station05:15LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 05:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 10m
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FlixBus10h 30m020:15BrusselsMidi Bus Station06:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 20:15:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 06:45:00. 50 Economy ticket for £24 per person are available. Travel duration is 10h 30m
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FlixBus11h 45m018:15BrusselsNorth Station06:00LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 08/12/2025 18:15:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 06:00:00. 50 Economy ticket for £28 per person are available. Travel duration is 11h 45m
Cheapest Buses Monday
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FlixBus10h 30m020:15BrusselsMidi Bus Station06:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 09/12/2025 20:15:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 06:45:00. 50 Economy ticket for £27 per person are available. Travel duration is 10h 30m
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FlixBus11h 5m016:15BrusselsNorth Station03:20LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 16:15:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 03:20:00. 50 Economy ticket for £30 per person are available. Travel duration is 11h 5m
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FlixBus11h 45m018:15BrusselsNorth Station06:00LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 18:15:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 06:00:00. 50 Economy ticket for £33 per person are available. Travel duration is 11h 45m
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FlixBus11h 50m012:00BrusselsNorth Station23:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 12:00:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 23:50:00. 50 Economy ticket for £34 per person are available. Travel duration is 11h 50m
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FlixBus13h 15m001:30BrusselsMidi Bus Station14:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 09/12/2025 01:30:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 14:45:00. 50 Economy ticket for £35 per person are available. Travel duration is 13h 15m
Cheapest Buses Tuesday
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FlixBus11h 30m013:40BrusselsMidi Bus Station01:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 13:40:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 01:10:00. 50 Economy ticket for £27 per person are available. Travel duration is 11h 30m
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FlixBus10h 30m020:15BrusselsMidi Bus Station06:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 20:15:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 06:45:00. 50 Economy ticket for £29 per person are available. Travel duration is 10h 30m
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FlixBus13h 15m001:30BrusselsMidi Bus Station14:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 01:30:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 14:45:00. 50 Economy ticket for £30 per person are available. Travel duration is 13h 15m
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FlixBus14h 0m000:45BrusselsNorth Station14:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 10/12/2025 00:45:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 14:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 14h 0m
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FlixBus14h 15m022:05BrusselsNorth Station12:20LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 10/12/2025 22:05:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 12:20:00. 50 Economy ticket for £33 per person are available. Travel duration is 14h 15m
Cheapest Buses Wednesday
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BlaBlaCar Bus12h 5m006:40BrusselsMidi Bus Station18:45LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 11/12/2025 06:40:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 18:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 12h 5m
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BlaBlaCar Bus10h 5m017:55BrusselsMidi Bus Station04:00LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 11/12/2025 17:55:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 04:00:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 5m
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BlaBlaCar Bus10h 45m013:30BrusselsMidi Bus Station00:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 11/12/2025 13:30:00 to Perrache Train Station, Lyon (France) arriving at 12/12/2025 00:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 45m
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FlixBus10h 30m020:15BrusselsMidi Bus Station06:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 11/12/2025 20:15:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 06:45:00. 50 Economy ticket for £24 per person are available. Travel duration is 10h 30m
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FlixBus11h 50m015:30BrusselsNorth Station03:20LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 15:30:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 03:20:00. 50 Economy ticket for £27 per person are available. Travel duration is 11h 50m
Cheapest Buses Thursday
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BlaBlaCar Bus12h 5m006:40BrusselsMidi Bus Station18:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 12/12/2025 06:40:00 to Perrache Train Station, Lyon (France) arriving at 12/12/2025 18:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 12h 5m
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BlaBlaCar Bus10h 45m013:30BrusselsMidi Bus Station00:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 12/12/2025 13:30:00 to Perrache Train Station, Lyon (France) arriving at 13/12/2025 00:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 45m
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BlaBlaCar Bus11h 25m007:20BrusselsMidi Bus Station18:45LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 12/12/2025 07:20:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 18:45:00. 50 Economy ticket for £21 per person are available. Travel duration is 11h 25m
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FlixBus10h 30m020:15BrusselsMidi Bus Station06:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 12/12/2025 20:15:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 06:45:00. 50 Economy ticket for £29 per person are available. Travel duration is 10h 30m
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FlixBus12h 20m022:55BrusselsNorth Station11:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 12/12/2025 22:55:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 11:15:00. 50 Economy ticket for £30 per person are available. Travel duration is 12h 20m
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Ryanair16h 15m021:15Brussels South Charleroi AirportBrussels South Charleroi Airport13:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 12/12/2025 21:15:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 13/12/2025 13:30:00. 50 Economy ticket for £109 per person are available. Travel duration is 16h 15m
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Skyscanner8h 10m014:40Brussels South Charleroi AirportBrussels South Charleroi Airport22:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 12/12/2025 14:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 12/12/2025 22:50:00. 50 Economy ticket for £114 per person are available. Travel duration is 8h 10m
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EasyJet Airline9h 0m013:25Brussels AirportBrussels Airport22:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Brussels Airport, Brussels Airport (Belgium) at 12/12/2025 13:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 12/12/2025 22:25:00. 50 Economy ticket for £121 per person are available. Travel duration is 9h 0m
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Austrian Airlines16h 10m019:55Brussels AirportBrussels Airport12:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Austrian Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 12/12/2025 19:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 13/12/2025 12:05:00. 50 Economy ticket for £127 per person are available. Travel duration is 16h 10m
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Vueling Airlines6h 25m009:05Brussels AirportBrussels Airport15:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 12/12/2025 09:05:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 12/12/2025 15:30:00. 50 Economy ticket for £130 per person are available. Travel duration is 6h 25m
Cheapest Buses Friday
Cheapest Flights Friday
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BlaBlaCar Bus11h 25m007:20BrusselsMidi Bus Station18:45LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 13/12/2025 07:20:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 18:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 11h 25m
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BlaBlaCar Bus10h 5m017:55BrusselsMidi Bus Station04:00LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 13/12/2025 17:55:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 04:00:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 5m
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BlaBlaCar Bus10h 45m013:30BrusselsMidi Bus Station00:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 13/12/2025 13:30:00 to Perrache Train Station, Lyon (France) arriving at 14/12/2025 00:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 45m
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FlixBus10h 55m014:15BrusselsMidi Bus Station01:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 13/12/2025 14:15:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 01:10:00. 50 Economy ticket for £26 per person are available. Travel duration is 10h 55m
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FlixBus10h 40m016:40BrusselsMidi Bus Station03:20LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 13/12/2025 16:40:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 03:20:00. 50 Economy ticket for £26 per person are available. Travel duration is 10h 40m
Cheapest Buses Saturday
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BlaBlaCar Bus11h 25m007:20BrusselsMidi Bus Station18:45LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 14/12/2025 07:20:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 18:45:00. 50 Economy ticket for £21 per person are available. Travel duration is 11h 25m
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BlaBlaCar Bus11h 25m007:20BrusselsMidi Bus Station18:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 14/12/2025 07:20:00 to Perrache Train Station, Lyon (France) arriving at 14/12/2025 18:45:00. 50 Economy ticket for £29 per person are available. Travel duration is 11h 25m
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BlaBlaCar Bus10h 5m017:55BrusselsMidi Bus Station04:00LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 14/12/2025 17:55:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 04:00:00. 50 Economy ticket for £30 per person are available. Travel duration is 10h 5m
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FlixBus12h 20m022:55BrusselsNorth Station11:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 14/12/2025 22:55:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 11:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 12h 20m
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FlixBus13h 15m001:30BrusselsMidi Bus Station14:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 14/12/2025 01:30:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 14:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 13h 15m
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Ryanair22h 55m008:50Brussels South Charleroi AirportBrussels South Charleroi Airport07:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 14/12/2025 08:50:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 07:45:00. 50 Economy ticket for £67 per person are available. Travel duration is 22h 55m
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Skyscanner10h 35m009:00Brussels South Charleroi AirportBrussels South Charleroi Airport19:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 14/12/2025 09:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 14/12/2025 19:35:00. 50 Economy ticket for £84 per person are available. Travel duration is 10h 35m
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Vueling Airlines9h 50m021:55Brussels AirportBrussels Airport07:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 14/12/2025 21:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 07:45:00. 50 Economy ticket for £91 per person are available. Travel duration is 9h 50m
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Brussels Airlines13h 20m018:25Brussels AirportBrussels Airport07:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 14/12/2025 18:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 07:45:00. 50 Economy ticket for £125 per person are available. Travel duration is 13h 20m
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EasyJet Airline25h 50m009:10Brussels AirportBrussels Airport11:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Brussels Airport, Brussels Airport (Belgium) at 14/12/2025 09:10:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 11:00:00. 50 Economy ticket for £144 per person are available. Travel duration is 25h 50m
Cheapest Buses Sunday
Cheapest Flights Sunday
What are the fastest trips from Brussels to Lyon?
You can get to Lyon from Brussels in just 6h 25m with a Flight from Vueling Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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BlaBlaCar Bus10h 10m019:05BrusselsMidi Bus Station05:15LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 19:05:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 05:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 10m
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FlixBus10h 30m020:15BrusselsMidi Bus Station06:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 20:15:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 06:45:00. 50 Economy ticket for £24 per person are available. Travel duration is 10h 30m
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BlaBlaCar Bus10h 45m013:30BrusselsMidi Bus Station00:15LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 13:30:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 00:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 45m
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BlaBlaCar Bus11h 25m007:20BrusselsMidi Bus Station18:45LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 08/12/2025 07:20:00 to Perrache Bus Stop, Lyon (France) arriving at 08/12/2025 18:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 11h 25m
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FlixBus11h 45m018:15BrusselsNorth Station06:00LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 08/12/2025 18:15:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 06:00:00. 50 Economy ticket for £28 per person are available. Travel duration is 11h 45m
Fastest Buses Monday
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FlixBus10h 30m020:15BrusselsMidi Bus Station06:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 09/12/2025 20:15:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 06:45:00. 50 Economy ticket for £27 per person are available. Travel duration is 10h 30m
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FlixBus11h 5m016:15BrusselsNorth Station03:20LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 16:15:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 03:20:00. 50 Economy ticket for £30 per person are available. Travel duration is 11h 5m
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FlixBus11h 45m018:15BrusselsNorth Station06:00LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 18:15:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 06:00:00. 50 Economy ticket for £33 per person are available. Travel duration is 11h 45m
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FlixBus11h 50m012:00BrusselsNorth Station23:50LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 09/12/2025 12:00:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 23:50:00. 50 Economy ticket for £34 per person are available. Travel duration is 11h 50m
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FlixBus13h 15m001:30BrusselsMidi Bus Station14:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 09/12/2025 01:30:00 to Perrache Bus Stop, Lyon (France) arriving at 09/12/2025 14:45:00. 50 Economy ticket for £35 per person are available. Travel duration is 13h 15m
Fastest Buses Tuesday
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FlixBus10h 30m020:15BrusselsMidi Bus Station06:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 20:15:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 06:45:00. 50 Economy ticket for £29 per person are available. Travel duration is 10h 30m
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FlixBus11h 30m013:40BrusselsMidi Bus Station01:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 13:40:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 01:10:00. 50 Economy ticket for £27 per person are available. Travel duration is 11h 30m
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FlixBus13h 15m001:30BrusselsMidi Bus Station14:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 10/12/2025 01:30:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 14:45:00. 50 Economy ticket for £30 per person are available. Travel duration is 13h 15m
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FlixBus14h 0m000:45BrusselsNorth Station14:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 10/12/2025 00:45:00 to Perrache Bus Stop, Lyon (France) arriving at 10/12/2025 14:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 14h 0m
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FlixBus14h 15m022:05BrusselsNorth Station12:20LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 10/12/2025 22:05:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 12:20:00. 50 Economy ticket for £33 per person are available. Travel duration is 14h 15m
Fastest Buses Wednesday
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BlaBlaCar Bus10h 5m017:55BrusselsMidi Bus Station04:00LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 11/12/2025 17:55:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 04:00:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 5m
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FlixBus10h 30m020:15BrusselsMidi Bus Station06:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 11/12/2025 20:15:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 06:45:00. 50 Economy ticket for £24 per person are available. Travel duration is 10h 30m
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BlaBlaCar Bus10h 45m013:30BrusselsMidi Bus Station00:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 11/12/2025 13:30:00 to Perrache Train Station, Lyon (France) arriving at 12/12/2025 00:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 45m
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FlixBus11h 50m015:30BrusselsNorth Station03:20LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 11/12/2025 15:30:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 03:20:00. 50 Economy ticket for £27 per person are available. Travel duration is 11h 50m
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BlaBlaCar Bus12h 5m006:40BrusselsMidi Bus Station18:45LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 11/12/2025 06:40:00 to Perrache Bus Stop, Lyon (France) arriving at 11/12/2025 18:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 12h 5m
Fastest Buses Thursday
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Vueling Airlines6h 25m009:05Brussels AirportBrussels Airport15:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 12/12/2025 09:05:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 12/12/2025 15:30:00. 50 Economy ticket for £130 per person are available. Travel duration is 6h 25m
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Skyscanner8h 10m014:40Brussels South Charleroi AirportBrussels South Charleroi Airport22:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 12/12/2025 14:40:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 12/12/2025 22:50:00. 50 Economy ticket for £114 per person are available. Travel duration is 8h 10m
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EasyJet Airline9h 0m013:25Brussels AirportBrussels Airport22:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Brussels Airport, Brussels Airport (Belgium) at 12/12/2025 13:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 12/12/2025 22:25:00. 50 Economy ticket for £121 per person are available. Travel duration is 9h 0m
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Austrian Airlines16h 10m019:55Brussels AirportBrussels Airport12:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Austrian Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 12/12/2025 19:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 13/12/2025 12:05:00. 50 Economy ticket for £127 per person are available. Travel duration is 16h 10m
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Ryanair16h 15m021:15Brussels South Charleroi AirportBrussels South Charleroi Airport13:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 12/12/2025 21:15:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 13/12/2025 13:30:00. 50 Economy ticket for £109 per person are available. Travel duration is 16h 15m
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FlixBus10h 30m020:15BrusselsMidi Bus Station06:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 12/12/2025 20:15:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 06:45:00. 50 Economy ticket for £29 per person are available. Travel duration is 10h 30m
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BlaBlaCar Bus10h 45m013:30BrusselsMidi Bus Station00:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 12/12/2025 13:30:00 to Perrache Train Station, Lyon (France) arriving at 13/12/2025 00:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 45m
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BlaBlaCar Bus11h 25m007:20BrusselsMidi Bus Station18:45LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 12/12/2025 07:20:00 to Perrache Bus Stop, Lyon (France) arriving at 12/12/2025 18:45:00. 50 Economy ticket for £21 per person are available. Travel duration is 11h 25m
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BlaBlaCar Bus12h 5m006:40BrusselsMidi Bus Station18:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 12/12/2025 06:40:00 to Perrache Train Station, Lyon (France) arriving at 12/12/2025 18:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 12h 5m
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FlixBus12h 20m022:55BrusselsNorth Station11:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 12/12/2025 22:55:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 11:15:00. 50 Economy ticket for £30 per person are available. Travel duration is 12h 20m
Fastest Flights Friday
Fastest Buses Friday
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BlaBlaCar Bus10h 5m017:55BrusselsMidi Bus Station04:00LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 13/12/2025 17:55:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 04:00:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 5m
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FlixBus10h 40m016:40BrusselsMidi Bus Station03:20LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 13/12/2025 16:40:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 03:20:00. 50 Economy ticket for £26 per person are available. Travel duration is 10h 40m
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BlaBlaCar Bus10h 45m013:30BrusselsMidi Bus Station00:15LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 13/12/2025 13:30:00 to Perrache Train Station, Lyon (France) arriving at 14/12/2025 00:15:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 45m
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FlixBus10h 55m014:15BrusselsMidi Bus Station01:10LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 13/12/2025 14:15:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 01:10:00. 50 Economy ticket for £26 per person are available. Travel duration is 10h 55m
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BlaBlaCar Bus11h 25m007:20BrusselsMidi Bus Station18:45LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 13/12/2025 07:20:00 to Perrache Bus Stop, Lyon (France) arriving at 13/12/2025 18:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 11h 25m
Fastest Buses Saturday
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Vueling Airlines9h 50m021:55Brussels AirportBrussels Airport07:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Vueling Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 14/12/2025 21:55:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 07:45:00. 50 Economy ticket for £91 per person are available. Travel duration is 9h 50m
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Skyscanner10h 35m009:00Brussels South Charleroi AirportBrussels South Charleroi Airport19:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Skyscanner goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 14/12/2025 09:00:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 14/12/2025 19:35:00. 50 Economy ticket for £84 per person are available. Travel duration is 10h 35m
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Brussels Airlines13h 20m018:25Brussels AirportBrussels Airport07:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Brussels Airlines goes from Brussels Airport, Brussels Airport (Belgium) at 14/12/2025 18:25:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 07:45:00. 50 Economy ticket for £125 per person are available. Travel duration is 13h 20m
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Ryanair22h 55m008:50Brussels South Charleroi AirportBrussels South Charleroi Airport07:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from Ryanair goes from Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) at 14/12/2025 08:50:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 07:45:00. 50 Economy ticket for £67 per person are available. Travel duration is 22h 55m
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EasyJet Airline25h 50m009:10Brussels AirportBrussels Airport11:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station0EconomyA Flight from EasyJet Airline goes from Brussels Airport, Brussels Airport (Belgium) at 14/12/2025 09:10:00 to Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) arriving at 15/12/2025 11:00:00. 50 Economy ticket for £144 per person are available. Travel duration is 25h 50m
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BlaBlaCar Bus10h 5m017:55BrusselsMidi Bus Station04:00LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 14/12/2025 17:55:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 04:00:00. 50 Economy ticket for £30 per person are available. Travel duration is 10h 5m
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BlaBlaCar Bus11h 25m007:20BrusselsMidi Bus Station18:45LyonPerrache Bus Stop0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 14/12/2025 07:20:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 18:45:00. 50 Economy ticket for £21 per person are available. Travel duration is 11h 25m
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BlaBlaCar Bus11h 25m007:20BrusselsMidi Bus Station18:45LyonPerrache Train Station0EconomyA Bus from BlaBlaCar Bus goes from Midi Bus Station, Brussels (Belgium) at 14/12/2025 07:20:00 to Perrache Train Station, Lyon (France) arriving at 14/12/2025 18:45:00. 50 Economy ticket for £29 per person are available. Travel duration is 11h 25m
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FlixBus12h 20m022:55BrusselsNorth Station11:15LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from North Station, Brussels (Belgium) at 14/12/2025 22:55:00 to Perrache Bus Stop, Lyon (France) arriving at 15/12/2025 11:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 12h 20m
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FlixBus13h 15m001:30BrusselsMidi Bus Station14:45LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Midi Bus Station, Brussels (Belgium) at 14/12/2025 01:30:00 to Perrache Bus Stop, Lyon (France) arriving at 14/12/2025 14:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 13h 15m
Fastest Flights Sunday
Fastest Buses Sunday
Here you will find all operators and timetables for a
Bus from Brussels to Lyon
What are the most popular stations in Brussels and Lyon?
In Brussels, you will usually depart from Midi Bus Station, North Station or Gare Centrale, while in Lyon you will be arriving at Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lyon from Brussels? With 6 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Brussels and Lyon, you can pay as low as £19 with a Bus from BlaBlaCar Bus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Vueling Airlines: you will get to Lyon in just 6h 25m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Brussels and Lyon are FlixBus, BlaBlaCar Bus and Ryanair, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Brussels and Lyon is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Saint-Gilles or to Caluire-et-Cuire, and look at flights from Brussels South Charleroi Airport, and landing at Lyons St. Exupery Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Brussels to Lyon?
The most popular companies between Brussels and Lyon, are FlixBus, BlaBlaCar Bus and Ryanair. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and BlaBlaCar Bus
Airlines: Ryanair, Skyscanner, EasyJet Airline and 3 more.
All you need to know when you travel from Brussels to Lyon
Check all information on comfort and services on all modes of transports from Brussels to Lyon. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Brussels to Lyon
How can I reach Lyon from Brussels?
Every day, there are on average 6 connections between Bus and Flight, with which you can get to Lyon from Brussels.
How far is Lyon from Brussels?
The distance between Brussels and Lyon is 567.4 km.
What is the most ecofriendly mode of transport between Brussels and Lyon?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 15 kgs of CO2, a train 20 kgs, a car 96 kgs, and a flight 140 kgs.
What is the cheapest mode of transport from Brussels to Lyon?
You can get to Lyon with just £19 by taking a Bus from BlaBlaCar Bus.
What is the fastest way to get from Brussels to Lyon?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lyon in just 6h 25m with a Flight from Vueling Airlines.
More routes to Brussels and to Lyon
Looking for more options? Here you can see the most popular routes to Brussels and to Lyon. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Brussels
- Amiens to Brussels
- Amsterdam to Brussels
- Antwerp to Brussels
- Barcelona to Brussels
- Basel to Brussels
- Birmingham to Brussels
- Bologna to Brussels
- Bordeaux to Brussels
- Brussels South Charleroi Airport to Brussels
- Dusseldorf to Brussels
- Lille to Brussels
- Linz to Brussels
- Lisbon to Brussels
- London to Brussels
- Lyon to Brussels
- Manchester to Brussels
- Munich to Brussels
- Nantes to Brussels
- Newcastle upon Tyne to Brussels
- Paris to Brussels
- The Hague to Brussels
- Toulouse to Brussels
- Vienna to Brussels
- Zurich to Brussels
- Trips to Lyon
- Alicante to Lyon
- Barcelona to Lyon
- Bern to Lyon
- Bordeaux to Lyon
- Braga to Lyon
- Caen to Lyon
- Dijon to Lyon
- Dusseldorf to Lyon
- Geneva to Lyon
- Grenoble to Lyon
- Liege to Lyon
- Lisbon to Lyon
- London to Lyon
- Lyons St. Exupery Airport to Lyon
- Marseille to Lyon
- Nantes to Lyon
- Nice to Lyon
- Paris to Lyon
- Poitiers to Lyon
- Rome to Lyon
- Sallanches to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon
