Compare all timetables for the bus from Rome to Lyon
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 15h 55m | 13:00 | Rome | Tiburtina Bus Station | 04:55 | Lyon | Perrache Bus Stop | Premium Economy | £25 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 21/03/2026 13:00:00 to Perrache Bus Stop, Lyon (France) arriving at 22/03/2026 04:55:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 15h 55m
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| Itabus | 14h 30m | 07:00 | Rome | Tiburtina Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £26 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 21/03/2026 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 21/03/2026 21:30:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 14h 30m
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| Itabus | 15h 10m | 21:45 | Rome | Tiburtina Bus Station | 12:55 | Lyon | Perrache Bus Stop | Premium Economy | £26 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 21/03/2026 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 22/03/2026 12:55:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 15h 10m
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| FlixBus | 14h 55m | 08:50 | Rome | Tiburtina Bus Station | 23:45 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £31 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 21/03/2026 08:50:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 21/03/2026 23:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 55m
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| FlixBus | 15h 20m | 17:25 | Rome | Anagnina Bus Station | 08:45 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £31 |
A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 21/03/2026 17:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 22/03/2026 08:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 15h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 16h 25m | 08:00 | Rome | Tiburtina Bus Station | 00:25 | Lyon | Perrache Bus Stop | Premium Economy | £33 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 22/03/2026 08:00:00 to Perrache Bus Stop, Lyon (France) arriving at 23/03/2026 00:25:00. 50 Premium Economy ticket for £33 per person are available. Travel duration is 16h 25m
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| Itabus | 15h 10m | 21:45 | Rome | Tiburtina Bus Station | 12:55 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Premium Economy | £38 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 22/03/2026 21:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 23/03/2026 12:55:00. 50 Premium Economy ticket for £38 per person are available. Travel duration is 15h 10m
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| Itabus | 15h 55m | 13:00 | Rome | Tiburtina Bus Station | 04:55 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Premium Economy | £53 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 22/03/2026 13:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 23/03/2026 04:55:00. 50 Premium Economy ticket for £53 per person are available. Travel duration is 15h 55m
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| FlixBus | 16h 0m | 20:00 | Rome | Tiburtina Bus Station | 12:00 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £66 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 22/03/2026 20:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 23/03/2026 12:00:00. 50 Economy ticket for £66 per person are available. Travel duration is 16h 0m
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| FlixBus | 17h 5m | 12:10 | Rome | Tiburtina Bus Station | 05:15 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £72 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 22/03/2026 12:10:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 23/03/2026 05:15:00. 50 Economy ticket for £72 per person are available. Travel duration is 17h 5m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 15h 10m | 21:45 | Rome | Tiburtina Bus Station | 12:55 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Premium Economy | £31 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 23/03/2026 21:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 24/03/2026 12:55:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 15h 10m
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| Itabus | 14h 30m | 07:00 | Rome | Tiburtina Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £32 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 23/03/2026 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 23/03/2026 21:30:00. 50 Premium Economy ticket for £32 per person are available. Travel duration is 14h 30m
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| FlixBus | 16h 0m | 20:00 | Rome | Tiburtina Bus Station | 12:00 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £54 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 23/03/2026 20:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 24/03/2026 12:00:00. 50 Economy ticket for £54 per person are available. Travel duration is 16h 0m
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| FlixBus | 16h 25m | 21:45 | Rome | Tiburtina Bus Station | 14:10 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £54 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 23/03/2026 21:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 24/03/2026 14:10:00. 50 Economy ticket for £54 per person are available. Travel duration is 16h 25m
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| FlixBus | 16h 20m | 22:45 | Rome | Tiburtina Bus Station | 15:05 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £54 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 23/03/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 24/03/2026 15:05:00. 50 Economy ticket for £54 per person are available. Travel duration is 16h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 15h 10m | 21:45 | Rome | Tiburtina Bus Station | 12:55 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Premium Economy | £26 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 24/03/2026 21:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 25/03/2026 12:55:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 15h 10m
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| FlixBus | 16h 0m | 20:00 | Rome | Tiburtina Bus Station | 12:00 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £51 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 24/03/2026 20:00:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 25/03/2026 12:00:00. 50 Economy ticket for £51 per person are available. Travel duration is 16h 0m
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| FlixBus | 17h 40m | 22:45 | Rome | Tiburtina Bus Station | 16:25 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £51 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 24/03/2026 22:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 25/03/2026 16:25:00. 50 Economy ticket for £51 per person are available. Travel duration is 17h 40m
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| FlixBus | 14h 45m | 13:05 | Rome | Anagnina Bus Station | 03:50 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £61 |
A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 24/03/2026 13:05:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 25/03/2026 03:50:00. 50 Economy ticket for £61 per person are available. Travel duration is 14h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 07:00 | Rome | Tiburtina Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £26 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 25/03/2026 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 25/03/2026 21:30:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 14h 30m
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| Itabus | 15h 10m | 21:45 | Rome | Tiburtina Bus Station | 12:55 | Lyon | Perrache Bus Stop | Premium Economy | £26 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 25/03/2026 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 26/03/2026 12:55:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 15h 10m
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| FlixBus | 14h 55m | 08:50 | Rome | Tiburtina Bus Station | 23:45 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £31 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 25/03/2026 08:50:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 25/03/2026 23:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 55m
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| FlixBus | 15h 20m | 17:25 | Rome | Anagnina Bus Station | 08:45 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £31 |
A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 25/03/2026 17:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 26/03/2026 08:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 15h 20m
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| BlaBlaCar Bus | 14h 45m | 15:20 | Rome | Tiburtina Bus Station | 06:05 | Lyon | Perrache Train Station | Economy | £37 |
A Bus from BlaBlaCar Bus goes from Tiburtina Bus Station, Rome (Italy) at 25/03/2026 15:20:00 to Perrache Train Station, Lyon (France) arriving at 26/03/2026 06:05:00. 50 Economy ticket for £37 per person are available. Travel duration is 14h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 07:00 | Rome | Tiburtina Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £26 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 26/03/2026 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 26/03/2026 21:30:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 14h 30m
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| Itabus | 15h 10m | 21:45 | Rome | Tiburtina Bus Station | 12:55 | Lyon | Perrache Bus Stop | Premium Economy | £26 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 26/03/2026 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 27/03/2026 12:55:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 15h 10m
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| FlixBus | 14h 55m | 07:45 | Rome | Tiburtina Bus Station | 22:40 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £31 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 26/03/2026 07:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 26/03/2026 22:40:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 55m
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| FlixBus | 14h 55m | 08:50 | Rome | Tiburtina Bus Station | 23:45 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £31 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 26/03/2026 08:50:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 26/03/2026 23:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 55m
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| FlixBus | 15h 20m | 17:25 | Rome | Anagnina Bus Station | 08:45 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £31 |
A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 26/03/2026 17:25:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 27/03/2026 08:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 15h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 07:00 | Rome | Tiburtina Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £26 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 27/03/2026 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 27/03/2026 21:30:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 14h 30m
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| Itabus | 16h 25m | 08:00 | Rome | Tiburtina Bus Station | 00:25 | Lyon | Perrache Bus Stop | Premium Economy | £28 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 27/03/2026 08:00:00 to Perrache Bus Stop, Lyon (France) arriving at 28/03/2026 00:25:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 16h 25m
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| FlixBus | 14h 55m | 07:45 | Rome | Tiburtina Bus Station | 22:40 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £31 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 27/03/2026 07:45:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 27/03/2026 22:40:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 55m
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| FlixBus | 14h 55m | 08:50 | Rome | Tiburtina Bus Station | 23:45 | Lyon | Lyon Avenue Tony Garnier Coach Stop | Economy | £31 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 27/03/2026 08:50:00 to Lyon Avenue Tony Garnier Coach Stop, Lyon (France) arriving at 27/03/2026 23:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 55m
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| Itabus | 15h 10m | 21:45 | Rome | Tiburtina Bus Station | 12:55 | Lyon | Perrache Bus Stop | Premium Economy | £34 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 27/03/2026 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 28/03/2026 12:55:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 15h 10m
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Best Price Offer: The price for the cheapest coach from Rome to Lyon is £22 on 18/03/2026. Flexible travellers save on ticket prices.
Frequency of bus connections between Rome and Lyon
Facts about coaches from Rome to Lyon
Compare all providers like FlixBus, Itabus and BlaBlaCar Bus that travel 20 times every day by bus from Rome to Lyon in one click! Book your bus ticket from Rome to Lyon starting from £22!
| Cheapest Bus | £22 |
| Fastest Bus | 14h 30m |
| Earliest Coach | 00:10 |
| Latest Coach | 23:50 |
| Daily Bus Connections | 20 Ø |
| Distance | 749.0 km |
| Coach Companies | FlixBus, Itabus and BlaBlaCar Bus |
Cheapest coach connections from Rome to Lyon
Every day, 20 buses from 3 coach companies leave Rome for Lyon: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 21/03/2026 and for the following days.
The cheapest time to travel from Rome to Lyon
How to save money travelling from Rome to Lyon
Book the ticket from Rome to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Lyon, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Rome to Lyon are also emptier.All bus stations and stops in Rome and Lyon
The map below shows you where to find all the bus stations in Rome and Lyon.
Compare the bus with other modes of transport
Service and Comfort on the bus from Rome to Lyon
FAQs about the Rome to Lyon bus
How much does a Rome - Lyon coach trip cost?
How much could I save by comparing buses from Rome to Lyon?
How many connections are available for the Rome - Lyon route on average every day?
How long does a bus to Lyon from Rome take?
What time is the first bus from Rome to Lyon?
What time is the last coach from Rome to Lyon?
Which bus companies serve the Rome - Lyon route?
Is there a direct bus between Rome and Lyon?
What can I take with me on the bus to Lyon from Rome?
What equipment is available for the Rome Lyon bus route?
How does CheckMyBus find the best bus deals from Rome to Lyon?
How does CheckMyBus technology work for trips from Rome to Lyon?
Available seat classes which are offered on the bus route Rome to Lyon
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
More bus routes to Rome and to Lyon
- Bus Routes to Rome
- Bus Avezzano to Rome
- Coach Barletta to Rome
- Bus to Rome from Cesena
- Coach from Ciro Marina to Rome
- Coach Civitavecchia to Rome
- Corigliano Calabro to Rome bus
- Coaches Florence to Rome
- Bus from Genoa to Rome
- Coach from Gioia Tauro to Rome
- Coach to Rome from London
- Coach Macerata to Rome
- Bus to Rome from Marsala
- Coach Nola to Rome
- Bus Pescara to Rome
- Coach Pompei to Rome
- Ravenna to Rome coach
- Bus to Rome from Rosarno
- Rossano to Rome bus
- Buses Termoli to Rome
- Buses Venice to Rome
- Bus Routes to Lyon
- Buses Aix-en-Provence to Lyon
- Bus from Alicante to Lyon
- Coaches Bari to Lyon
- Basel to Lyon coach
- Bus Biarritz to Lyon
- Coach from Bourg-Saint-Maurice (Val d’Isère) to Lyon
- Coaches Bristol to Lyon
- Coach from Freiburg to Lyon
- Coach from Geneva to Lyon
- Gijón to Lyon coach
- Bus from Liege to Lyon
- Lisbon to Lyon bus
- Madrid to Lyon bus
- Coaches Manchester to Lyon
- Coach from Metz to Lyon
- Bus Rennes to Lyon
- Tignes to Lyon bus
- Buses Toulon to Lyon
- Coach Val-d'Isère to Lyon
- Bus to Lyon from Zurich
