Bus tickets Rome to Lyon from £22

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Compare all timetables for the bus from Rome to Lyon

Here is a selection of the cheapest bus trips from the schedule from Rome to Lyon from various bus operators like FlixBus or Itabus for the next days.

today
£72
tomorrow
£59
Tuesday
£38
Wednesday
£38
Thursday
£24
Friday
£28
Saturday
£33

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 16h 15m 21:55 Rome Tiburtina Bus Station 14:10 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £72
Itabus 15h 15m 21:45 Rome Tiburtina Bus Station 13:00 Lyon Perrache Bus Stop  Premium Economy £75
FlixBus 15h 20m 17:25 Rome Anagnina Bus Station 08:45 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £88
FlixBus 16h 20m 22:45 Rome Tiburtina Bus Station 15:05 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £115
  • Did you know that if you travel from Rome to Lyon via Grenoble, you can save more than £22? You can find the corresponding connections below.
    • Itabus
      17h 0m
      0
      08:00
      Rome
      Tiburtina Bus Station
      23:05
      Grenoble
      Hotel Terminus
      0
      Itabus
      Premium Economy
      £45
      • Waiting Time 0h 25m
    • FlixBus
      1h 30m
      0
      23:30
      Grenoble
      Coach Station
      01:00
      Lyon
      Lyon Avenue Tony Garnier Coach Stop
      0
      FlixBus
      Economy
      £5
    Travel time is 1h 45m longer, but you will save £22

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 16h 30m 08:00 Rome Tiburtina Bus Station 00:30 Lyon Perrache Bus Stop  Premium Economy £59
Itabus 15h 15m 21:45 Rome Tiburtina Bus Station 13:00 Lyon Lyon Avenue Tony Garnier Coach Stop  Premium Economy £65
FlixBus 14h 55m 07:45 Rome Tiburtina Bus Station 22:40 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £75
FlixBus 15h 5m 08:50 Rome Tiburtina Bus Station 23:55 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £80
FlixBus 14h 50m 13:05 Rome Anagnina Bus Station 03:55 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £87
  • Did you know that if you travel from Rome to Lyon via Grenoble, you can save more than £9? You can find the corresponding connections below.
    • Itabus
      17h 0m
      0
      08:00
      Rome
      Tiburtina Bus Station
      23:05
      Grenoble
      Hotel Terminus
      0
      Itabus
      Premium Economy
      £45
      • Waiting Time 0h 25m
    • FlixBus
      1h 30m
      0
      23:30
      Grenoble
      Coach Station
      01:00
      Lyon
      Lyon Avenue Tony Garnier Coach Stop
      0
      FlixBus
      Economy
      £5
    Travel time is 2h 10m longer, but you will save £9

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 16h 30m 08:00 Rome Tiburtina Bus Station 00:30 Lyon Perrache Bus Stop  Premium Economy £38
FlixBus 14h 50m 13:05 Rome Anagnina Bus Station 03:55 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £61
Itabus 15h 15m 21:45 Rome Tiburtina Bus Station 13:00 Lyon Lyon Avenue Tony Garnier Coach Stop  Premium Economy £65
FlixBus 16h 20m 22:45 Rome Tiburtina Bus Station 15:05 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £69
FlixBus 15h 5m 08:50 Rome Tiburtina Bus Station 23:55 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £71

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 16h 30m 08:00 Rome Tiburtina Bus Station 00:30 Lyon Perrache Bus Stop  Premium Economy £38
FlixBus 15h 20m 17:25 Rome Anagnina Bus Station 08:45 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £43
Itabus 15h 15m 21:45 Rome Tiburtina Bus Station 13:00 Lyon Perrache Bus Stop  Premium Economy £59
FlixBus 15h 40m 17:05 Rome Tiburtina Bus Station 08:45 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £62
FlixBus 16h 0m 20:00 Rome Tiburtina Bus Station 12:00 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £62

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 16h 30m 08:00 Rome Tiburtina Coach Station 00:30 Lyon Perrache Bus Stop  Economy £24
FlixBus 15h 20m 17:25 Rome Anagnina Bus Station 08:45 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £38
FlixBus 14h 55m 07:45 Rome Tiburtina Bus Station 22:40 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £45
FlixBus 16h 15m 21:55 Rome Tiburtina Bus Station 14:10 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £58
Itabus 15h 15m 21:45 Rome Tiburtina Bus Station 13:00 Lyon Perrache Bus Stop  Premium Economy £59

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 16h 30m 08:00 Rome Tiburtina Bus Station 00:30 Lyon Perrache Bus Stop  Premium Economy £28
FlixBus 15h 20m 17:25 Rome Anagnina Bus Station 08:45 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £39
FlixBus 14h 55m 07:45 Rome Tiburtina Bus Station 22:40 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £59
FlixBus 16h 15m 21:55 Rome Tiburtina Bus Station 14:10 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £59
Itabus 15h 15m 21:45 Rome Tiburtina Bus Station 13:00 Lyon Perrache Bus Stop  Premium Economy £59

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Itabus 16h 30m 08:00 Rome Tiburtina Bus Station 00:30 Lyon Perrache Bus Stop  Premium Economy £33
FlixBus 15h 20m 17:25 Rome Anagnina Bus Station 08:45 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £45
Itabus 15h 15m 21:45 Rome Tiburtina Bus Station 13:00 Lyon Perrache Bus Stop  Premium Economy £50
FlixBus 14h 55m 07:45 Rome Tiburtina Bus Station 22:40 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £54
FlixBus 15h 5m 08:50 Rome Tiburtina Bus Station 23:55 Lyon Lyon Avenue Tony Garnier Coach Stop  Economy £59
  • Did you know that if you travel from Rome to Lyon via Grenoble, you can save more than £3? You can find the corresponding connections below.
    • Itabus
      17h 0m
      0
      08:00
      Rome
      Tiburtina Bus Station
      23:05
      Grenoble
      Coach Station
      0
      Itabus
      Premium Economy
      £24
      • Waiting Time 0h 25m
    • FlixBus
      1h 30m
      0
      23:30
      Grenoble
      Coach Station
      01:00
      Lyon
      Lyon Avenue Tony Garnier Coach Stop
      0
      FlixBus
      Economy
      £5
    Travel time is 2h 5m longer, but you will save £3

Best Price Offer: The price for the cheapest coach from Rome to Lyon is £22 on 19/11/2026. Flexible travellers save on ticket prices.


Frequency of bus connections between Rome and Lyon

See here how frequent the connections between Rome and Lyon are, during different times and days of the week.
Thursday is the busiest day, with more than 20 daily coaches from Rome to Lyon. Tuesday has instead the fewest connections, with only 12 daily coaches between Rome and Lyon.
The busiest time of the day is the Evening, with 52 coaches from Rome to Lyon, while Night sees the fewest connections between Rome and Lyon, with 7 offers.

Facts about coaches from Rome to Lyon

Compare all providers like FlixBus and Itabus that travel 17 times every day by bus from Rome to Lyon in one click! Book your bus ticket from Rome to Lyon starting from £22!

Cheapest Bus £22
Fastest Bus 14h 50m
Earliest Coach 11:00
Latest Coach 22:45
Daily Bus Connections 17 Ø
Distance 749.0 km
Coach Companies FlixBus and Itabus

Cheapest coach connections from Rome to Lyon

Every day, 17 buses from 2 coach companies leave Rome for Lyon: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 01/11/2026 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 26/10
Tuesday 27/10
Wednesday 28/10
Thursday 29/10
Friday 30/10
Saturday 31/10
Sunday 01/11
£72
Monday 02/11
£125
Tuesday 03/11
£31
Wednesday 04/11
£38
Thursday 05/11
£33
Friday 06/11
£27
Saturday 07/11
£33
Sunday 08/11
£33
Monday 09/11
£49
Tuesday 10/11
£51
Wednesday 11/11
£26
Thursday 12/11
£30
Friday 13/11
£39
Saturday 14/11
£25
Sunday 15/11
£42
Monday 16/11
£26
Tuesday 17/11
£42
Wednesday 18/11
£29
Thursday 19/11
£22
Friday 20/11
£48
Saturday 21/11
£25
Sunday 22/11

The cheapest time to travel from Rome to Lyon

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Lyon, for the next 30 days.
With a price starting from £22, Thursday is the cheapest day for a coach from Rome to Lyon. Sunday instead is the most expensive day with prices starting from £33.
Night is the cheapest day time for bus tickets from Rome to Lyon, with £22. Evening is the most expensive time of the day with prices starting from £50.

How to save money travelling from Rome to Lyon

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Lyon, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Rome to Lyon are also emptier.

All bus stations and stops in Rome and Lyon

The map below shows you where to find all the bus stations in Rome and Lyon.

Service and Comfort on the bus from Rome to Lyon

Want to know which seat classes are available on the coaches from Rome to Lyon? Or which bus companies serve the route Rome to Lyon? Below you will find answers to your questions.

FAQs about the Rome to Lyon bus

How much does a Rome - Lyon coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Rome - Lyon bus trip is available from £22 and takes 16h 30m. Compare offers and save money!

How much could I save by comparing buses from Rome to Lyon?

The connection Rome to Lyon is offered by 2 companies with ticket prices ranging from £22 to £173. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Rome - Lyon route on average every day?

Each day, the bus route from Rome to Lyon is offered by roughly 17 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Lyon from Rome take?

The quickest coach from Rome to Lyon is provided by FlixBus and takes 14h 50m. Coach tickets for this connection cost £87. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Rome to Lyon?

The earliest bus to Lyon departs from Rome at 11:00. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Rome to Lyon?

The latest bus to Lyon departs from Rome at 22:45. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Rome - Lyon route?

Passengers looking to travel from Rome to Lyon can travel with FlixBus and Itabus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Rome and Lyon?

You can check all the direct connections between Rome and Lyon by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Itabus.

What can I take with me on the bus to Lyon from Rome?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Rome Lyon bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Lyon bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Lyon on your planned travel date.

How does CheckMyBus find the best bus deals from Rome to Lyon?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 17 daily trips between Rome and Lyon. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Lyon?

Prices and availability for 17 trips between Rome and Lyon change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Lyon

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Rome and to Lyon

Here’s an overview of the most popular bus routes to Rome and to Lyon. Simply click on the connection of your choice, and you will find all the details about your bus route!
Castel di Lama to Rome bus Castel di Lama to Rome bus
Coach to Rome from Deruta Coach to Rome from Deruta
Ortona to Rome bus Ortona to Rome bus
Coaches Rimini to Rome Coaches Rimini to Rome
Nantes to Lyon bus Nantes to Lyon bus
Bus from Naples to Lyon Bus from Naples to Lyon
Coach to Lyon from Brussels Coach to Lyon from Brussels
Coaches Bristol to Lyon Coaches Bristol to Lyon
Popular Airport Transfers to Rome and to Lyon
CheckMyBus › Coaches in Italy › Coach to Rome › Coach to Lyon

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