Bus tickets Rome to Lyon from £38

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Compare all timetables for the bus from Rome to Lyon

Here is a selection of the cheapest bus trips from the schedule from Rome to Lyon from various bus operators like FlixBus, Itabus or BlaBlaCar Bus for the next days.
today
from £43
tomorrow
from £39
Tuesday
from £38
Wednesday
from £39
Thursday
from £38
Friday
from £40
Saturday
from £40

Cheapest bus trips today

Prices are for one way and one person
  • Itabus
    14h 30m
    0
    07:00
    Rome
    Tiburtina Bus Station
    21:30
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £43
  • Itabus
    14h 30m
    0
    07:00
    Rome
    Tiburtina Bus Station
    21:30
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £47
  • FlixBus
    14h 55m
    0
    07:45
    Rome
    Tiburtina Bus Station
    22:40
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £48
  • Itabus
    14h 30m
    0
    07:00
    Rome
    Tiburtina Bus Station
    21:30
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Economy
    £54
  • FlixBus
    15h 20m
    0
    17:25
    Rome
    Anagnina Bus Station
    08:45
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £61

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Itabus
    14h 30m
    0
    07:00
    Rome
    Tiburtina Bus Station
    21:30
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £39
  • Itabus
    14h 30m
    0
    07:00
    Rome
    Tiburtina Bus Station
    21:30
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £43
  • BlaBlaCar Bus
    14h 50m
    0
    15:20
    Rome
    Tiburtina Bus Station
    06:10
    Lyon
    Perrache Bus Stop
    0
    BlaBlaCar Bus
    Economy
    £45
  • FlixBus
    14h 55m
    0
    07:45
    Rome
    Tiburtina Bus Station
    22:40
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £46
  • FlixBus
    15h 20m
    0
    17:25
    Rome
    Anagnina Bus Station
    08:45
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £48
  • Did you know that if you travel from Rome to Lyon via Grenoble, you can save more than £4? You can find the corresponding connections below.
    • FlixBus
      21h 30m
      0
      10:15
      Rome
      Tiburtina Bus Station
      23:45
      Grenoble
      Coach Station
      0
      FlixBus
      Economy
      £29
      • Waiting Time 6h 30m
    • FlixBus
      1h 30m
      0
      06:15
      Grenoble
      Coach Station
      07:45
      Lyon
      Perrache Bus Stop
      0
      FlixBus
      Economy
      £6
    Travel time is 7h 0m longer, but you will save £4

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Itabus
    14h 30m
    0
    07:00
    Rome
    Tiburtina Bus Station
    21:30
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £38
  • Itabus
    15h 10m
    0
    21:45
    Rome
    Tiburtina Bus Station
    12:55
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £38
  • Itabus
    14h 30m
    0
    07:00
    Rome
    Tiburtina Bus Station
    21:30
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £43
  • FlixBus
    14h 55m
    0
    08:50
    Rome
    Tiburtina Bus Station
    23:45
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £50
  • FlixBus
    15h 20m
    0
    17:25
    Rome
    Anagnina Bus Station
    08:45
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £56

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Itabus
    14h 30m
    0
    07:00
    Rome
    Tiburtina Bus Station
    21:30
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £39
  • Itabus
    14h 30m
    0
    07:00
    Rome
    Tiburtina Bus Station
    21:30
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £40
  • Itabus
    15h 10m
    0
    21:45
    Rome
    Tiburtina Bus Station
    12:55
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £40
  • FlixBus
    15h 20m
    0
    17:25
    Rome
    Anagnina Bus Station
    08:45
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £44
  • FlixBus
    14h 55m
    0
    08:50
    Rome
    Tiburtina Bus Station
    23:45
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £46
  • Did you know that if you travel from Rome to Lyon via Grenoble, you can save more than £4? You can find the corresponding connections below.
    • FlixBus
      20h 30m
      0
      10:15
      Rome
      Tiburtina Bus Station
      23:45
      Grenoble
      Coach Station
      0
      FlixBus
      Economy
      £31
      • Waiting Time 5h 30m
    • BlaBlaCar Bus
      1h 30m
      0
      05:15
      Grenoble
      Coach Station
      06:45
      Lyon
      Perrache Train Station
      0
      BlaBlaCar Bus
      Economy
      £4
    Travel time is 6h 0m longer, but you will save £4

Cheapest bus trips Thursday

Prices are for one way and one person
  • Itabus
    14h 30m
    0
    07:00
    Rome
    Tiburtina Bus Station
    21:30
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £38
  • Itabus
    15h 10m
    0
    21:45
    Rome
    Tiburtina Bus Station
    12:55
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £38
  • FlixBus
    14h 55m
    0
    07:45
    Rome
    Tiburtina Bus Station
    22:40
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £43
  • Itabus
    14h 30m
    0
    07:00
    Rome
    Tiburtina Bus Station
    21:30
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £43
  • FlixBus
    15h 20m
    0
    17:25
    Rome
    Anagnina Bus Station
    08:45
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £44

Cheapest bus trips Friday

Prices are for one way and one person
  • Itabus
    14h 30m
    0
    07:00
    Rome
    Tiburtina Bus Station
    21:30
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £40
  • FlixBus
    15h 20m
    0
    17:25
    Rome
    Anagnina Bus Station
    08:45
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £44
  • Itabus
    14h 30m
    0
    07:00
    Rome
    Tiburtina Bus Station
    21:30
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £45
  • FlixBus
    14h 55m
    0
    07:45
    Rome
    Tiburtina Bus Station
    22:40
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £46
  • Itabus
    15h 10m
    0
    21:45
    Rome
    Tiburtina Bus Station
    12:55
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £47
  • Did you know that if you travel from Rome to Lyon via Grenoble, you can save more than £5? You can find the corresponding connections below.
    • FlixBus
      20h 30m
      0
      10:15
      Rome
      Tiburtina Bus Station
      23:45
      Grenoble
      Coach Station
      0
      FlixBus
      Economy
      £31
      • Waiting Time 5h 30m
    • BlaBlaCar Bus
      1h 30m
      0
      05:15
      Grenoble
      Coach Station
      06:45
      Lyon
      Perrache Train Station
      0
      BlaBlaCar Bus
      Economy
      £4
    Travel time is 6h 0m longer, but you will save £5

Cheapest bus trips Saturday

Prices are for one way and one person
  • Itabus
    15h 10m
    0
    21:45
    Rome
    Tiburtina Bus Station
    12:55
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £40
  • Itabus
    14h 30m
    0
    07:00
    Rome
    Tiburtina Bus Station
    21:30
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £43
  • Itabus
    14h 30m
    0
    07:00
    Rome
    Tiburtina Bus Station
    21:30
    Lyon
    Perrache Bus Stop
    0
    Itabus
    Premium Economy
    £43
  • FlixBus
    14h 55m
    0
    07:45
    Rome
    Tiburtina Bus Station
    22:40
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £44
  • FlixBus
    15h 20m
    0
    17:25
    Rome
    Anagnina Bus Station
    08:45
    Lyon
    Perrache Bus Stop
    0
    FlixBus
    Economy
    £44
  • Did you know that if you travel from Rome to Lyon via Grenoble, you can save more than £5? You can find the corresponding connections below.
    • FlixBus
      20h 30m
      0
      10:15
      Rome
      Tiburtina Bus Station
      23:45
      Grenoble
      Coach Station
      0
      FlixBus
      Economy
      £31
      • Waiting Time 5h 30m
    • BlaBlaCar Bus
      1h 30m
      0
      05:15
      Grenoble
      Coach Station
      06:45
      Lyon
      Perrache Train Station
      0
      BlaBlaCar Bus
      Economy
      £4
    Travel time is 6h 0m longer, but you will save £5

Frequency of bus connections between Rome and Lyon

See here how frequent the connections between Rome and Lyon are, during different times and days of the week.
Saturday is the busiest day, with more than 21 daily coaches from Rome to Lyon. Tuesday has instead the fewest connections, with only 16 daily coaches between Rome and Lyon.
The busiest time of the day is the Evening, with 59 coaches from Rome to Lyon, while Night sees the fewest connections between Rome and Lyon, with 14 offers.

Facts about coaches from Rome to Lyon

Compare all providers like FlixBus, Itabus and BlaBlaCar Bus that travel 19 times every day by bus from Rome to Lyon in one click! Book your bus ticket from Rome to Lyon starting from £38!

Cheapest Bus £38
Fastest Bus 14h 30m
Earliest Coach 00:10
Latest Coach 23:50
Daily Bus Connections 19 Ø
Distance 749.0 km
Coach Companies FlixBus, Itabus and BlaBlaCar Bus

Cheapest coach connections from Rome to Lyon

Every day, 19 buses from 3 coach companies leave Rome for Lyon: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 23/06/2025 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 16/06
Tuesday 17/06
Wednesday 18/06
Thursday 19/06
Friday 20/06
Saturday 21/06
Sunday 22/06
£43
Monday 23/06
£43
Tuesday 24/06
£38
Wednesday 25/06
£44
Thursday 26/06
£43
Friday 27/06
£44
Saturday 28/06
£38
Sunday 29/06
£40
Monday 30/06
£40
Tuesday 01/07
£38
Wednesday 02/07
£38
Thursday 03/07
£38
Friday 04/07
£38
Saturday 05/07
£44
Sunday 06/07
£44
Monday 07/07
£47
Tuesday 08/07
£38
Wednesday 09/07
£34
Thursday 10/07
£34
Friday 11/07
£47
Saturday 12/07
£40
Sunday 13/07

The cheapest time to travel from Rome to Lyon

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Lyon, for the next 30 days.
With a price starting from £38, Tuesday is the cheapest day for a coach from Rome to Lyon. Sunday instead is the most expensive day with prices starting from £43.
Morning is the cheapest day time for bus tickets from Rome to Lyon, with £38. Night is the most expensive time of the day with prices starting from £50.

How to save money travelling from Rome to Lyon

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Lyon, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Rome to Lyon are also emptier.

All bus stations and stops in Rome and Lyon

The map below shows you where to find all the bus stations in Rome and Lyon.

Service and Comfort on the bus from Rome to Lyon

Want to know which seat classes are available on the coaches from Rome to Lyon? Or which bus companies serve the route Rome to Lyon? Below you will find answers to your questions.

FAQs about the Rome to Lyon bus

How much does a Rome - Lyon coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Rome - Lyon bus trip is available from £38 and takes 14h 30m. Compare offers and save money!

How much could I save by comparing buses from Rome to Lyon?

The connection Rome to Lyon is offered by 3 companies with ticket prices ranging from £38 to £114. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Rome - Lyon route on average every day?

Each day, the bus route from Rome to Lyon is offered by roughly 19 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Lyon from Rome take?

The quickest coach from Rome to Lyon is provided by Itabus and takes 14h 30m. Coach tickets for this connection cost £43. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Rome to Lyon?

The earliest bus to Lyon departs from Rome at 00:10. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Rome to Lyon?

The latest bus to Lyon departs from Rome at 23:50. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Rome - Lyon route?

Passengers looking to travel from Rome to Lyon can travel with FlixBus, Itabus and BlaBlaCar Bus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Rome and Lyon?

You can check all the direct connections between Rome and Lyon by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Itabus and BlaBlaCar Bus.

What can I take with me on the bus to Lyon from Rome?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Rome Lyon bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Lyon bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Lyon on your planned travel date.

Available seat classes which are offered on the bus route Rome to Lyon

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Rome and to Lyon

Here’s an overview of the most popular bus routes to Rome and to Lyon. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Potenza to Rome Buses Potenza to Rome
Ascoli Piceno to Rome bus Ascoli Piceno to Rome bus
Buses Reggio Calabria to Rome Buses Reggio Calabria to Rome
Taranto to Rome coach Taranto to Rome coach
Buses Birmingham to Lyon Buses Birmingham to Lyon
Coach Lorient to Lyon Coach Lorient to Lyon
Coach Val-d'Isère to Lyon Coach Val-d'Isère to Lyon
Tignes to Lyon bus Tignes to Lyon bus
Popular Airport Transfers to Rome and to Lyon
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