Compare all timetables for the bus from Rome to Lyon
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 15h 10m | 21:45 | Rome | Tiburtina Bus Station | 12:55 | Lyon | Perrache Bus Stop | Economy | £34 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 18/12/2025 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 12:55:00. 50 Economy ticket for £34 per person are available. Travel duration is 15h 10m
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| Itabus | 16h 25m | 08:00 | Rome | Tiburtina Bus Station | 00:25 | Lyon | Perrache Bus Stop | Premium Economy | £38 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 18/12/2025 08:00:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 00:25:00. 50 Premium Economy ticket for £38 per person are available. Travel duration is 16h 25m
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| Itabus | 15h 55m | 13:00 | Rome | Tiburtina Bus Station | 04:55 | Lyon | Perrache Bus Stop | Premium Economy | £50 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 18/12/2025 13:00:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 04:55:00. 50 Premium Economy ticket for £50 per person are available. Travel duration is 15h 55m
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| FlixBus | 14h 55m | 07:45 | Rome | Tiburtina Bus Station | 22:40 | Lyon | Perrache Bus Stop | Economy | £57 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 18/12/2025 07:45:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 22:40:00. 50 Economy ticket for £57 per person are available. Travel duration is 14h 55m
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| FlixBus | 14h 55m | 08:50 | Rome | Tiburtina Bus Station | 23:45 | Lyon | Perrache Bus Stop | Economy | £59 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 18/12/2025 08:50:00 to Perrache Bus Stop, Lyon (France) arriving at 18/12/2025 23:45:00. 50 Economy ticket for £59 per person are available. Travel duration is 14h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 16h 25m | 08:00 | Rome | Tiburtina Bus Station | 00:25 | Lyon | Perrache Bus Stop | Premium Economy | £28 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 08:00:00 to Perrache Bus Stop, Lyon (France) arriving at 20/12/2025 00:25:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 16h 25m
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| Itabus | 15h 25m | 09:00 | Rome | Tiburtina Bus Station | 00:25 | Lyon | Perrache Bus Stop | Premium Economy | £28 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 09:00:00 to Perrache Bus Stop, Lyon (France) arriving at 20/12/2025 00:25:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 15h 25m
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| Itabus | 14h 30m | 07:00 | Rome | Tiburtina Bus Station | 21:30 | Lyon | Perrache Bus Stop | Economy | £34 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 21:30:00. 50 Economy ticket for £34 per person are available. Travel duration is 14h 30m
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| FlixBus | 14h 55m | 07:45 | Rome | Tiburtina Bus Station | 22:40 | Lyon | Perrache Bus Stop | Economy | £61 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 07:45:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 22:40:00. 50 Economy ticket for £61 per person are available. Travel duration is 14h 55m
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| FlixBus | 14h 55m | 08:50 | Rome | Tiburtina Bus Station | 23:45 | Lyon | Perrache Bus Stop | Economy | £61 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 08:50:00 to Perrache Bus Stop, Lyon (France) arriving at 19/12/2025 23:45:00. 50 Economy ticket for £61 per person are available. Travel duration is 14h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 15h 20m | 17:25 | Rome | Anagnina Bus Station | 08:45 | Lyon | Perrache Bus Stop | Economy | £28 |
A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 20/12/2025 17:25:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 08:45:00. 50 Economy ticket for £28 per person are available. Travel duration is 15h 20m
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| Itabus | 15h 10m | 21:45 | Rome | Tiburtina Bus Station | 12:55 | Lyon | Perrache Bus Stop | Premium Economy | £47 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 20/12/2025 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 12:55:00. 50 Premium Economy ticket for £47 per person are available. Travel duration is 15h 10m
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| Itabus | 14h 30m | 07:00 | Rome | Tiburtina Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £58 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 20/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 20/12/2025 21:30:00. 50 Premium Economy ticket for £58 per person are available. Travel duration is 14h 30m
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| Itabus | 18h 55m | 10:00 | Rome | Tiburtina Bus Station | 04:55 | Lyon | Perrache Bus Stop | Premium Economy | £58 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 20/12/2025 10:00:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 04:55:00. 50 Premium Economy ticket for £58 per person are available. Travel duration is 18h 55m
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| FlixBus | 14h 55m | 07:45 | Rome | Tiburtina Bus Station | 22:40 | Lyon | Perrache Bus Stop | Economy | £75 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 20/12/2025 07:45:00 to Perrache Bus Stop, Lyon (France) arriving at 20/12/2025 22:40:00. 50 Economy ticket for £75 per person are available. Travel duration is 14h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 16h 25m | 08:00 | Rome | Tiburtina Bus Station | 00:25 | Lyon | Perrache Bus Stop | Premium Economy | £23 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 21/12/2025 08:00:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 00:25:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 16h 25m
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| Itabus | 15h 25m | 09:00 | Rome | Tiburtina Bus Station | 00:25 | Lyon | Perrache Bus Stop | Premium Economy | £23 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 21/12/2025 09:00:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 00:25:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 15h 25m
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| Itabus | 14h 30m | 07:00 | Rome | Tiburtina Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £30 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 21/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 21:30:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 14h 30m
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| FlixBus | 14h 55m | 07:45 | Rome | Tiburtina Bus Station | 22:40 | Lyon | Perrache Bus Stop | Economy | £66 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 21/12/2025 07:45:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 22:40:00. 50 Economy ticket for £66 per person are available. Travel duration is 14h 55m
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| FlixBus | 14h 55m | 08:50 | Rome | Tiburtina Bus Station | 23:45 | Lyon | Perrache Bus Stop | Economy | £68 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 21/12/2025 08:50:00 to Perrache Bus Stop, Lyon (France) arriving at 21/12/2025 23:45:00. 50 Economy ticket for £68 per person are available. Travel duration is 14h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 07:00 | Rome | Tiburtina Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £30 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 22/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 21:30:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 14h 30m
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| Itabus | 15h 10m | 21:45 | Rome | Tiburtina Bus Station | 12:55 | Lyon | Perrache Bus Stop | Economy | £34 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 22/12/2025 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 23/12/2025 12:55:00. 50 Economy ticket for £34 per person are available. Travel duration is 15h 10m
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| Itabus | 16h 25m | 08:00 | Rome | Tiburtina Bus Station | 00:25 | Lyon | Perrache Bus Stop | Premium Economy | £35 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 22/12/2025 08:00:00 to Perrache Bus Stop, Lyon (France) arriving at 23/12/2025 00:25:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 16h 25m
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| FlixBus | 14h 55m | 08:50 | Rome | Tiburtina Bus Station | 23:45 | Lyon | Perrache Bus Stop | Economy | £66 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 22/12/2025 08:50:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 23:45:00. 50 Economy ticket for £66 per person are available. Travel duration is 14h 55m
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| FlixBus | 14h 55m | 07:45 | Rome | Tiburtina Bus Station | 22:40 | Lyon | Perrache Bus Stop | Economy | £68 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 22/12/2025 07:45:00 to Perrache Bus Stop, Lyon (France) arriving at 22/12/2025 22:40:00. 50 Economy ticket for £68 per person are available. Travel duration is 14h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 07:00 | Rome | Tiburtina Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £35 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 23/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 23/12/2025 21:30:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 14h 30m
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| Itabus | 15h 10m | 21:45 | Rome | Tiburtina Bus Station | 12:55 | Lyon | Perrache Bus Stop | Premium Economy | £44 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 23/12/2025 21:45:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 12:55:00. 50 Premium Economy ticket for £44 per person are available. Travel duration is 15h 10m
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| FlixBus | 15h 20m | 17:25 | Rome | Anagnina Bus Station | 08:45 | Lyon | Perrache Bus Stop | Economy | £70 |
A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 23/12/2025 17:25:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 08:45:00. 50 Economy ticket for £70 per person are available. Travel duration is 15h 20m
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| FlixBus | 14h 55m | 08:50 | Rome | Tiburtina Bus Station | 23:45 | Lyon | Perrache Bus Stop | Economy | £72 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 23/12/2025 08:50:00 to Perrache Bus Stop, Lyon (France) arriving at 23/12/2025 23:45:00. 50 Economy ticket for £72 per person are available. Travel duration is 14h 55m
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| FlixBus | 18h 55m | 23:50 | Rome | Tiburtina Bus Station | 18:45 | Lyon | Perrache Bus Stop | Economy | £82 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 23/12/2025 23:50:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 18:45:00. 50 Economy ticket for £82 per person are available. Travel duration is 18h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 07:00 | Rome | Tiburtina Bus Station | 21:30 | Lyon | Perrache Bus Stop | Premium Economy | £49 |
A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 24/12/2025 07:00:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 21:30:00. 50 Premium Economy ticket for £49 per person are available. Travel duration is 14h 30m
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| FlixBus | 14h 55m | 08:50 | Rome | Tiburtina Bus Station | 23:45 | Lyon | Perrache Bus Stop | Economy | £68 |
A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 24/12/2025 08:50:00 to Perrache Bus Stop, Lyon (France) arriving at 24/12/2025 23:45:00. 50 Economy ticket for £68 per person are available. Travel duration is 14h 55m
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| BlaBlaCar Bus | 14h 50m | 15:20 | Rome | Tiburtina Bus Station | 06:10 | Lyon | Perrache Bus Stop | Economy | £70 |
A Bus from BlaBlaCar Bus goes from Tiburtina Bus Station, Rome (Italy) at 24/12/2025 15:20:00 to Perrache Bus Stop, Lyon (France) arriving at 25/12/2025 06:10:00. 50 Economy ticket for £70 per person are available. Travel duration is 14h 50m
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| FlixBus | 15h 20m | 17:25 | Rome | Anagnina Bus Station | 08:45 | Lyon | Perrache Bus Stop | Economy | £72 |
A Bus from FlixBus goes from Anagnina Bus Station, Rome (Italy) at 24/12/2025 17:25:00 to Perrache Bus Stop, Lyon (France) arriving at 25/12/2025 08:45:00. 50 Economy ticket for £72 per person are available. Travel duration is 15h 20m
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Distribusion17h 35m007:00RomeTiburtina Bus Station20:00ChamberyCoach Station0Premium EconomyA Bus from Distribusion goes from Tiburtina Bus Station, Rome (Italy) at 22/12/2025 07:00:00 to Coach Station, Chambery (France) arriving at 22/12/2025 20:00:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 13h 0m
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FlixBus1h 20m023:15ChamberyCoach Station00:35LyonPerrache Bus Stop0EconomyA Bus from FlixBus goes from Coach Station, Chambery (France) at 22/12/2025 23:15:00 to Perrache Bus Stop, Lyon (France) arriving at 23/12/2025 00:35:00. 50 Economy ticket for £8 per person are available. Travel duration is 1h 20m
Waiting Time 3h 15m -
Best Price Offer: The price for the cheapest coach from Rome to Lyon is £23 on 21/12/2025. Flexible travellers save on ticket prices.
Frequency of bus connections between Rome and Lyon
Facts about coaches from Rome to Lyon
Compare all providers like Itabus, FlixBus and BlaBlaCar Bus that travel 26 times every day by bus from Rome to Lyon in one click! Book your bus ticket from Rome to Lyon starting from £23!
| Cheapest Bus | £23 |
| Fastest Bus | 14h 30m |
| Earliest Coach | 07:45 |
| Latest Coach | 23:50 |
| Daily Bus Connections | 26 Ø |
| Distance | 749.0 km |
| Coach Companies | Itabus, FlixBus and BlaBlaCar Bus |
Cheapest coach connections from Rome to Lyon
Every day, 26 buses from 3 coach companies leave Rome for Lyon: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 18/12/2025 and for the following days.
The cheapest time to travel from Rome to Lyon
How to save money travelling from Rome to Lyon
Book the ticket from Rome to Lyon in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Lyon, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Rome to Lyon are also emptier.All bus stations and stops in Rome and Lyon
The map below shows you where to find all the bus stations in Rome and Lyon.
Compare the bus with other modes of transport
Service and Comfort on the bus from Rome to Lyon
FAQs about the Rome to Lyon bus
How much does a Rome - Lyon coach trip cost?
How much could I save by comparing buses from Rome to Lyon?
How many connections are available for the Rome - Lyon route on average every day?
How long does a bus to Lyon from Rome take?
What time is the first bus from Rome to Lyon?
What time is the last coach from Rome to Lyon?
Which bus companies serve the Rome - Lyon route?
Is there a direct bus between Rome and Lyon?
What can I take with me on the bus to Lyon from Rome?
What equipment is available for the Rome Lyon bus route?
How does CheckMyBus find the best bus deals from Rome to Lyon?
How does CheckMyBus technology work for trips from Rome to Lyon?
Available seat classes which are offered on the bus route Rome to Lyon
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
More bus routes to Rome and to Lyon
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- Bus to Rome from Rosarno
- Rossano to Rome bus
- Bus Sala Consilina to Rome
- Coach to Rome from San Severo
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- Bus Routes to Lyon
- Coaches Bari to Lyon
- Bus Brest to Lyon
- Bus to Lyon from Clermont-Ferrand
- Bus Dijon to Lyon
- Coach from Freiburg to Lyon
- Coach from Geneva to Lyon
- Coach Genoa to Lyon
- Bus from La Rochelle to Lyon
- Lisbon to Lyon bus
- Coach London to Lyon
- Coaches Manchester to Lyon
- Coach from Metz to Lyon
- Bus to Lyon from Montpellier
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- Bus to Lyon from Nottingham
- Coach from Paris to Lyon
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- Porto to Lyon coach
- Buses Saint-Étienne to Lyon
- Coach from Strasbourg to Lyon

