Which bus from Antofagasta to Santiago, RM is the best?
Check the bus schedule for Antofagasta to Santiago, RM. Here is a selection of the cheapest coach trips for the next days from bus operators like Pullman San Andres, Pluss Chile or Cikbus Elité. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pullman San Andres | 18h 30m | 13:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 07:30 | Santiago, RM | Terminal San Borja | Premium Economy | £27 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 01/08/2026 13:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 02/08/2026 07:30:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 18h 30m
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| Cormar Bus | 18h 25m | 23:45 | Antofagasta | Camus Coach Station | 18:10 | Santiago, RM | Terminal San Borja | Premium Economy | £28 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 01/08/2026 23:45:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 02/08/2026 18:10:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 18h 25m
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| Cikbus Elité | 18h 50m | 22:10 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:00 | Santiago, RM | Sur Bus Station | Premium Economy | £32 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 01/08/2026 22:10:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 02/08/2026 17:00:00. 50 Premium Economy ticket for £32 per person are available. Travel duration is 18h 50m
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| Pullman Bus | 19h 15m | 11:30 | Antofagasta | Camus Coach Station | 06:45 | Santiago, RM | Terminal San Borja | First Class | £33 |
A Bus from Pullman Bus goes from Camus Coach Station, Antofagasta (Chile) at 01/08/2026 11:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 02/08/2026 06:45:00. 50 First Class ticket for £33 per person are available. Travel duration is 19h 15m
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| FlixBus | 18h 0m | 03:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 21:35 | Santiago, RM | Terminal San Borja | Economy | £33 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 01/08/2026 03:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 01/08/2026 21:35:00. 50 Economy ticket for £33 per person are available. Travel duration is 18h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cikbus Elité | 21h 0m | 08:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 05:30 | Santiago, RM | Terminal San Borja | Business | £27 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 02/08/2026 08:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 03/08/2026 05:30:00. 50 Business ticket for £27 per person are available. Travel duration is 21h 0m
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| Pullman San Andres | 18h 30m | 13:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 07:30 | Santiago, RM | Terminal San Borja | Premium Economy | £27 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 02/08/2026 13:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 03/08/2026 07:30:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 18h 30m
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| Cormar Bus | 18h 25m | 23:45 | Antofagasta | Camus Coach Station | 18:10 | Santiago, RM | Terminal San Borja | Premium Economy | £28 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 02/08/2026 23:45:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 03/08/2026 18:10:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 18h 25m
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| FlixBus | 18h 0m | 03:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 21:35 | Santiago, RM | Terminal San Borja | Economy | £32 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 02/08/2026 03:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 02/08/2026 21:35:00. 50 Economy ticket for £32 per person are available. Travel duration is 18h 0m
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| Pluss Chile | 17h 30m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Sur Bus Station | Premium Economy | £41 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 02/08/2026 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 02/08/2026 17:35:00. 50 Premium Economy ticket for £41 per person are available. Travel duration is 17h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pullman San Andres | 18h 30m | 13:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 07:30 | Santiago, RM | Terminal San Borja | Premium Economy | £27 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 03/08/2026 13:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/08/2026 07:30:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 18h 30m
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| Cormar Bus | 18h 25m | 23:45 | Antofagasta | Camus Coach Station | 18:10 | Santiago, RM | Terminal San Borja | Premium Economy | £28 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 03/08/2026 23:45:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/08/2026 18:10:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 18h 25m
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| Pluss Chile | 17h 30m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Sur Bus Station | Premium Economy | £29 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 03/08/2026 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 03/08/2026 17:35:00. 50 Premium Economy ticket for £29 per person are available. Travel duration is 17h 30m
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| FlixBus | 19h 35m | 18:20 | Antofagasta | Carlos Oviedo Cavada Bus Station | 13:55 | Santiago, RM | Terminal San Borja | Economy | £30 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 03/08/2026 18:20:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/08/2026 13:55:00. 50 Economy ticket for £30 per person are available. Travel duration is 19h 35m
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| Nueva Andimar Vip | 18h 0m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 19:35 | Santiago, RM | Terminal San Borja | Economy | £31 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 03/08/2026 01:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 03/08/2026 19:35:00. 50 Economy ticket for £31 per person are available. Travel duration is 18h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cikbus Elité | 18h 50m | 03:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 22:20 | Santiago, RM | Terminal San Borja | Business | £27 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 04/08/2026 03:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/08/2026 22:20:00. 50 Business ticket for £27 per person are available. Travel duration is 18h 50m
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| Pullman San Andres | 18h 30m | 13:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 07:30 | Santiago, RM | Terminal San Borja | Premium Economy | £27 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 04/08/2026 13:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/08/2026 07:30:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 18h 30m
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| Nueva Andimar Vip | 18h 0m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 19:35 | Santiago, RM | Terminal San Borja | Economy | £29 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 04/08/2026 01:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/08/2026 19:35:00. 50 Economy ticket for £29 per person are available. Travel duration is 18h 0m
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| FlixBus | 19h 35m | 18:20 | Antofagasta | Carlos Oviedo Cavada Bus Station | 13:55 | Santiago, RM | Terminal San Borja | Economy | £29 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 04/08/2026 18:20:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/08/2026 13:55:00. 50 Economy ticket for £29 per person are available. Travel duration is 19h 35m
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| Chile Bus | 18h 15m | 23:15 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:30 | Santiago, RM | Terminal San Borja | First Class | £32 |
A Bus from Chile Bus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 04/08/2026 23:15:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/08/2026 17:30:00. 50 First Class ticket for £32 per person are available. Travel duration is 18h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cormar Bus | 18h 30m | 01:00 | Antofagasta | Camus Coach Station | 19:30 | Santiago, RM | Terminal San Borja | Premium Economy | £26 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 05/08/2026 01:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/08/2026 19:30:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 18h 30m
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| Pullman San Andres | 18h 30m | 13:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 07:30 | Santiago, RM | Terminal San Borja | Premium Economy | £27 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/08/2026 13:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 06/08/2026 07:30:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 18h 30m
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| Cikbus Elité | 18h 50m | 03:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 22:20 | Santiago, RM | Terminal San Borja | Business | £27 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/08/2026 03:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/08/2026 22:20:00. 50 Business ticket for £27 per person are available. Travel duration is 18h 50m
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| Nueva Andimar Vip | 18h 0m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 19:35 | Santiago, RM | Terminal San Borja | Economy | £29 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/08/2026 01:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/08/2026 19:35:00. 50 Economy ticket for £29 per person are available. Travel duration is 18h 0m
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| Pluss Chile | 17h 30m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Sur Bus Station | Premium Economy | £41 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/08/2026 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/08/2026 17:35:00. 50 Premium Economy ticket for £41 per person are available. Travel duration is 17h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cormar Bus | 18h 30m | 01:00 | Antofagasta | Camus Coach Station | 19:30 | Santiago, RM | Terminal San Borja | Premium Economy | £26 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 06/08/2026 01:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 06/08/2026 19:30:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 18h 30m
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| Pullman San Andres | 18h 30m | 13:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 07:30 | Santiago, RM | Terminal San Borja | Premium Economy | £27 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/08/2026 13:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 07/08/2026 07:30:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 18h 30m
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| Nueva Andimar Vip | 18h 0m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 19:35 | Santiago, RM | Terminal San Borja | Economy | £29 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/08/2026 01:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 06/08/2026 19:35:00. 50 Economy ticket for £29 per person are available. Travel duration is 18h 0m
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| FlixBus | 19h 35m | 18:20 | Antofagasta | Carlos Oviedo Cavada Bus Station | 13:55 | Santiago, RM | Terminal San Borja | Economy | £29 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/08/2026 18:20:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 07/08/2026 13:55:00. 50 Economy ticket for £29 per person are available. Travel duration is 19h 35m
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| Pluss Chile | 17h 30m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Sur Bus Station | Premium Economy | £41 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/08/2026 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 06/08/2026 17:35:00. 50 Premium Economy ticket for £41 per person are available. Travel duration is 17h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pullman San Andres | 18h 30m | 13:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 07:30 | Santiago, RM | Terminal San Borja | Premium Economy | £27 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/08/2026 13:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 08/08/2026 07:30:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 18h 30m
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| Cormar Bus | 18h 25m | 23:45 | Antofagasta | Camus Coach Station | 18:10 | Santiago, RM | Terminal San Borja | Premium Economy | £28 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 07/08/2026 23:45:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 08/08/2026 18:10:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 18h 25m
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| FlixBus | 18h 0m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 19:35 | Santiago, RM | Terminal San Borja | Economy | £30 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/08/2026 01:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 07/08/2026 19:35:00. 50 Economy ticket for £30 per person are available. Travel duration is 18h 0m
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| Cikbus Elité | 21h 0m | 08:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 05:30 | Santiago, RM | Sur Bus Station | Premium Economy | £32 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/08/2026 08:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 08/08/2026 05:30:00. 50 Premium Economy ticket for £32 per person are available. Travel duration is 21h 0m
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| Pullman Bus | 20h 0m | 01:00 | Antofagasta | Camus Coach Station | 21:00 | Santiago, RM | Terminal San Borja | First Class | £40 |
A Bus from Pullman Bus goes from Camus Coach Station, Antofagasta (Chile) at 07/08/2026 01:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 07/08/2026 21:00:00. 50 First Class ticket for £40 per person are available. Travel duration is 20h 0m
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Best Price Offer: The price for the cheapest coach from Antofagasta to Santiago, RM is £24 on 15/08/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Antofagasta and Santiago, RM?
All facts for Antofagasta to Santiago, RM bus at a glance
Compare all coach operators like Pullman San Andres, Pluss Chile and Cikbus Elité that travel daily 95 times by bus from Antofagasta to Santiago, RM in one click. Book your Antofagasta to Santiago, RM bus ticket starting from £24!
| Cheapest Bus | £24 |
| Fastest Bus | 17h 0m |
| Earliest Coach | 03:30 |
| Latest Coach | 23:50 |
| Daily Bus Connections | 95 Ø |
| Distance | 1,089.2 km |
| Coach Companies | Pullman San Andres, Pluss Chile, Cikbus Elité, Pullman Bus, Nueva Andimar Vip, FlixBus, Cormar Bus and Chile Bus |
What are the cheapest coach tickets from Antofagasta to Santiago, RM?
Every day, 95 buses from 8 coach companies leave Antofagasta for Santiago, RM. Check the table below to find the cheapest prices for coach tickets for this route, starting from 01/08/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Antofagasta to Santiago, RM
How to save money travelling from Antofagasta to Santiago, RM
Book the ticket from Antofagasta to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Antofagasta to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Antofagasta to Santiago, RM are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Antofagasta and Santiago, RM
Here is a map with all coach stations in Antofagasta and Santiago, RM. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Antofagasta to Santiago, RM
FAQs for Antofagasta to Santiago, RM bus
How much does a Antofagasta Santiago, RM coach trip cost?
How much could I save by comparing buses from Antofagasta to Santiago, RM?
How many connections are available for the Antofagasta Santiago, RM route on average every day?
How long does a bus to Santiago, RM from Antofagasta take?
What time is the first bus from Antofagasta to Santiago, RM?
What time is the last coach from Antofagasta to Santiago, RM?
Which bus companies serve the Antofagasta Santiago, RM route?
Is there a direct bus between Antofagasta and Santiago, RM?
What can I take with me on the bus to Santiago, RM from Antofagasta?
What equipment is available for the Antofagasta Santiago, RM bus route?
How does CheckMyBus find the best coach deals from Antofagasta to Santiago, RM?
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Available seat classes which are offered on the bus route Antofagasta to Santiago, RM
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
Comfortable seating, food and drink service, accompanied generally by ticket flexibility.
Best of the best: you will find the most comfortable accommodation to work or relax during your travel.
More bus routes to Antofagasta and to Santiago, RM
- Bus Routes to Antofagasta
- Bus Arica, AP to Antofagasta
- Bus to Antofagasta from Baquedano
- Coach from Calama to Antofagasta
- Coach to Antofagasta from Concepción
- Coach from Coquimbo to Antofagasta
- Bus Iquique to Antofagasta
- La Calera to Antofagasta coach
- Bus to Antofagasta from Los Vilos
- Coach to Antofagasta from Mejillones
- Coaches Oruro to Antofagasta
- Coach Pozo Almonte to Antofagasta
- Bus from Sierra Gorda to Antofagasta
- Buses Vallenar to Antofagasta
- Coach to Antofagasta from Valparaíso (CL)
- Bus Viña del Mar to Antofagasta
- Bus Routes to Santiago, RM
- Coach Ancud to Santiago, RM
- Calama to Santiago, RM bus
- Bus Cauquenes to Santiago, RM
- Coquimbo to Santiago, RM bus
- Bus from Coronel to Santiago, RM
- Bus to Santiago, RM from Cunco
- Bus from Lanco to Santiago, RM
- Lautaro to Santiago, RM coach
- Coach Loncoche to Santiago, RM
- Bus to Santiago, RM from Los Vilos
- Coach from Ovalle to Santiago, RM
- Bus from Papudo to Santiago, RM
- Pitrufquén to Santiago, RM coach
- Coach to Santiago, RM from Puerto Montt
- Bus to Santiago, RM from Puerto Varas
- Bus São Paulo to Santiago, RM
- Bus Talca, ML to Santiago, RM
- Coaches Villa Alemana to Santiago, RM
- Bus Villarrica (CL) to Santiago, RM
- Coach Viña del Mar to Santiago, RM
