Which bus from Antofagasta to Santiago, RM is the cheapest?

Compare all coach companies and find the best price: Bus tickets from £20
Compare & Save Millions of buses in one click. Save up to 70%!
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Which bus from Antofagasta to Santiago, RM is the best?

Check the bus schedule for Antofagasta to Santiago, RM. Here is a selection of the cheapest coach trips for the next days from bus operators like Cikbus Elité, Pluss Chile or Pullman San Andres. To see the full timetable for all coaches just use or search and compare.

today
£25
tomorrow
£20
Monday
£25
Tuesday
£25
Wednesday
£25
Thursday
£25
Friday
£25

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 18h 0m 03:35 Antofagasta Carlos Oviedo Cavada Bus Station 21:35 Santiago, RM Terminal San Borja  Economy £25
Cormar Bus 17h 50m 20:20 Antofagasta Camus Coach Station 14:10 Santiago, RM Terminal San Borja  First Class £32
Pullman San Andres 18h 30m 11:00 Antofagasta Carlos Oviedo Cavada Bus Station 05:30 Santiago, RM Terminal San Borja  Premium Economy £33
Pullman Bus 18h 30m 17:30 Antofagasta Camus Coach Station 12:00 Santiago, RM Terminal San Borja  First Class £33
Pluss Chile 18h 20m 03:00 Antofagasta Carlos Oviedo Cavada Bus Station 21:20 Santiago, RM Sur Bus Station  Premium Economy £34

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cikbus Elité 21h 0m 08:30 Antofagasta Carlos Oviedo Cavada Bus Station 05:30 Santiago, RM Terminal San Borja  Business £20
Cormar Bus 18h 11m 23:59 Antofagasta Camus Coach Station 18:10 Santiago, RM Terminal San Borja  Premium Economy £25
FlixBus 19h 35m 23:30 Antofagasta Carlos Oviedo Cavada Bus Station 19:05 Santiago, RM Terminal San Borja  Business £25
Nueva Andimar Vip 18h 0m 03:35 Antofagasta Carlos Oviedo Cavada Bus Station 21:35 Santiago, RM Terminal San Borja  Economy £25
Pullman San Andres 18h 30m 23:30 Antofagasta Carlos Oviedo Cavada Bus Station 18:00 Santiago, RM Terminal San Borja  Premium Economy £30

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 18h 0m 01:35 Antofagasta Carlos Oviedo Cavada Bus Station 19:35 Santiago, RM Terminal San Borja  Economy £25
Cikbus Elité 18h 40m 01:10 Antofagasta Carlos Oviedo Cavada Bus Station 19:50 Santiago, RM Terminal San Borja  First Class £27
Pullman San Andres 18h 30m 23:30 Antofagasta Carlos Oviedo Cavada Bus Station 18:00 Santiago, RM Terminal San Borja  Premium Economy £30
Cormar Bus 17h 10m 21:05 Antofagasta Camus Coach Station 14:15 Santiago, RM Terminal San Borja  First Class £32
Pluss Chile 17h 30m 00:05 Antofagasta Carlos Oviedo Cavada Bus Station 17:35 Santiago, RM Sur Bus Station  Premium Economy £34

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 18h 0m 01:35 Antofagasta Carlos Oviedo Cavada Bus Station 19:35 Santiago, RM Terminal San Borja  Economy £25
Cikbus Elité 18h 40m 01:10 Antofagasta Carlos Oviedo Cavada Bus Station 19:50 Santiago, RM Terminal San Borja  First Class £27
Cormar Bus 18h 11m 23:59 Antofagasta Camus Coach Station 18:10 Santiago, RM Terminal San Borja  Premium Economy £27
Pullman San Andres 18h 30m 23:30 Antofagasta Carlos Oviedo Cavada Bus Station 18:00 Santiago, RM Terminal San Borja  Premium Economy £33
FlixBus 22h 25m 22:00 Antofagasta Carlos Oviedo Cavada Bus Station 20:25 Santiago, RM Los Libertadores Bus Stop  Economy £33

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 18h 0m 01:35 Antofagasta Carlos Oviedo Cavada Bus Station 19:35 Santiago, RM Terminal San Borja  Economy £25
Cikbus Elité 18h 50m 03:10 Antofagasta Carlos Oviedo Cavada Bus Station 22:00 Santiago, RM Terminal San Borja  Business £31
Cormar Bus 17h 10m 13:00 Antofagasta Carlos Oviedo Cavada Bus Station 06:10 Santiago, RM Terminal San Borja  First Class £32
Pullman San Andres 18h 30m 23:30 Antofagasta Carlos Oviedo Cavada Bus Station 18:00 Santiago, RM Terminal San Borja  Premium Economy £33
Pluss Chile 17h 30m 00:05 Antofagasta Carlos Oviedo Cavada Bus Station 17:35 Santiago, RM Sur Bus Station  Premium Economy £34

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 18h 11m 23:59 Antofagasta Camus Coach Station 18:10 Santiago, RM Terminal San Borja  Premium Economy £25
Nueva Andimar Vip 18h 0m 01:35 Antofagasta Carlos Oviedo Cavada Bus Station 19:35 Santiago, RM Terminal San Borja  Economy £25
FlixBus 19h 35m 23:30 Antofagasta Carlos Oviedo Cavada Bus Station 19:05 Santiago, RM Terminal San Borja  Business £30
Pullman San Andres 18h 30m 23:30 Antofagasta Carlos Oviedo Cavada Bus Station 18:00 Santiago, RM Terminal San Borja  Premium Economy £33
Pluss Chile 17h 30m 00:05 Antofagasta Carlos Oviedo Cavada Bus Station 17:35 Santiago, RM Sur Bus Station  Premium Economy £34

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 18h 0m 01:35 Antofagasta Carlos Oviedo Cavada Bus Station 19:35 Santiago, RM Terminal San Borja  Economy £25
Cikbus Elité 20h 0m 10:00 Antofagasta Carlos Oviedo Cavada Bus Station 06:00 Santiago, RM Terminal San Borja  First Class £28
Pullman San Andres 18h 30m 23:30 Antofagasta Carlos Oviedo Cavada Bus Station 18:00 Santiago, RM Terminal San Borja  Premium Economy £30
Cormar Bus 18h 0m 19:40 Antofagasta Camus Coach Station 13:40 Santiago, RM Terminal San Borja  First Class £32
FlixBus 19h 35m 22:00 Antofagasta Carlos Oviedo Cavada Bus Station 17:35 Santiago, RM Terminal San Borja  Economy £32

Best Price Offer: The price for the cheapest coach from Antofagasta to Santiago, RM is £20 on 14/12/2025. Flexible travellers save on ticket prices.


What is the best day and time to travel by bus between Antofagasta and Santiago, RM?

Here is the frequency of all coach connections from Antofagasta to Santiago, RM. See on which day of the week you have more travel options and what time you have more bus trips to choose from.
Friday is the busiest day, with more than 137 daily coaches from Antofagasta to Santiago, RM. Saturday has instead the fewest connections, with only 53 daily coaches between Antofagasta and Santiago, RM.
The busiest time of the day is the Evening, with 367 coaches from Antofagasta to Santiago, RM, while Morning sees the fewest connections between Antofagasta and Santiago, RM, with 81 offers.

All facts for Antofagasta to Santiago, RM bus at a glance

Compare all coach operators like Cikbus Elité, Pluss Chile and Pullman San Andres that travel daily 109 times by bus from Antofagasta to Santiago, RM in one click. Book your Antofagasta to Santiago, RM bus ticket starting from £20!

Cheapest Bus £20
Fastest Bus 17h 0m
Earliest Coach 03:00
Latest Coach 23:50
Daily Bus Connections 109 Ø
Distance 1,089.2 km
Coach Companies Cikbus Elité, Pluss Chile, Pullman San Andres, Pullman Bus, Nueva Andimar Vip, FlixBus, Cormar Bus and Chile Bus

What are the cheapest coach tickets from Antofagasta to Santiago, RM?

Every day, 109 buses from 8 coach companies leave Antofagasta for Santiago, RM. Check the table below to find the cheapest prices for coach tickets for this route, starting from 13/12/2025 and for the following days. Make sure get the cheapest bus ticket!

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 08/12
Tuesday 09/12
Wednesday 10/12
Thursday 11/12
Friday 12/12
Saturday 13/12
£32
Sunday 14/12
£25
Monday 15/12
£25
Tuesday 16/12
£30
Wednesday 17/12
£25
Thursday 18/12
£25
Friday 19/12
£25
Saturday 20/12
£25
Sunday 21/12
£25
Monday 22/12
£32
Tuesday 23/12
£30
Wednesday 24/12
£25
Thursday 25/12
£25
Friday 26/12
£25
Saturday 27/12
£25
Sunday 28/12
£25
Monday 29/12
£25
Tuesday 30/12
£25
Wednesday 31/12
£25
Thursday 01/01
£30
Friday 02/01
£30
Saturday 03/01
£25
Sunday 04/01

The cheapest time to travel from Antofagasta to Santiago, RM

See here on which day and which time of the day you can find the cheapest bus ticket from Antofagasta to Santiago, RM, for the next 30 days.
With a price starting from £20, Sunday is the cheapest day for a coach from Antofagasta to Santiago, RM. Monday instead is the most expensive day with prices starting from £25.
Morning is the cheapest day time for bus tickets from Antofagasta to Santiago, RM, with £20. Afternoon is the most expensive time of the day with prices starting from £25.

How to save money travelling from Antofagasta to Santiago, RM

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Antofagasta to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Antofagasta to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Antofagasta to Santiago, RM are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

All bus stations and stops in Antofagasta and Santiago, RM

Here is a map with all coach stations in Antofagasta and Santiago, RM. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Antofagasta to Santiago, RM? Compare all modes of transports from Antofagasta to Santiago, RM.

All you need to know when you travel by bus from Antofagasta to Santiago, RM

Check all information on comfort and services on the coaches from Antofagasta to Santiago, RM. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Antofagasta to Santiago, RM bus

How much does a Antofagasta Santiago, RM coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Antofagasta Santiago, RM bus trip is available from £20 and takes 21h 0m. Compare offers and save money!

How much could I save by comparing buses from Antofagasta to Santiago, RM?

This connection is offered by 8 companies with ticket prices ranging from £20 to £51. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Santiago, RM.

How many connections are available for the Antofagasta Santiago, RM route on average every day?

Each day, the bus route from Antofagasta to Santiago, RM is offered by roughly 109 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Santiago, RM from Antofagasta take?

The quickest coach from Antofagasta to Santiago, RM is provided by Pullman San Andres and takes 17h 0m. Coach tickets for this connection cost £42. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Antofagasta to Santiago, RM?

The earliest bus to Santiago, RM departs from Antofagasta at 03:00. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Antofagasta to Santiago, RM?

The latest bus to Santiago, RM departs from Antofagasta at 23:50. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Antofagasta Santiago, RM route?

Passengers looking to travel from Antofagasta to Santiago, RM can travel with Cikbus Elité, Pluss Chile and Pullman San Andres. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Antofagasta and Santiago, RM?

You can check all the direct connections between Antofagasta and Santiago, RM by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Cikbus Elité, Pluss Chile and Pullman San Andres.

What can I take with me on the bus to Santiago, RM from Antofagasta?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Antofagasta Santiago, RM bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Antofagasta Santiago, RM bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Antofagasta to Santiago, RM on your planned travel date.

How does CheckMyBus find the best coach deals from Antofagasta to Santiago, RM?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 109 daily trips between Antofagasta and Santiago, RM. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Antofagasta to Santiago, RM?

Prices and availability for 109 trips between Antofagasta and Santiago, RM change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Antofagasta to Santiago, RM

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Antofagasta and to Santiago, RM

Here’s an overview of the most popular bus routes to Antofagasta and to Santiago, RM. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
Bus Iquique to Antofagasta Bus Iquique to Antofagasta
Coaches Oruro to Antofagasta Coaches Oruro to Antofagasta
Coach from Coquimbo to Antofagasta Coach from Coquimbo to Antofagasta
Coaches Ovalle to Antofagasta Coaches Ovalle to Antofagasta
Calama to Santiago, RM bus Calama to Santiago, RM bus
Coquimbo to Santiago, RM bus Coquimbo to Santiago, RM bus
Copiapó to Santiago, RM coach Copiapó to Santiago, RM coach
Bus Villarrica (CL) to Santiago, RM Bus Villarrica (CL) to Santiago, RM
Popular Airport Transfers to Antofagasta and to Santiago, RM
CheckMyBus › Coaches in Chile › Coach to Antofagasta › Coach to Santiago, RM

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

deals,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

for

ads

personalisation.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.