Which bus from Antofagasta to Santiago, RM is the best?
Check the bus schedule for Antofagasta to Santiago, RM. Here is a selection of the cheapest coach trips for the next days from bus operators like Pullman San Andres, Cikbus Elité or Pluss Chile. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Andimar | 18h 0m | 03:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 21:35 | Santiago, RM | Terminal San Borja | Economy | £27 |
A Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 31/10/2026 03:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 31/10/2026 21:35:00. 50 Economy ticket for £27 per person are available. Travel duration is 18h 0m
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| Cormar Bus | 18h 20m | 11:00 | Antofagasta | Camus Coach Station | 05:20 | Santiago, RM | Terminal San Borja | Premium Economy | £29 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 31/10/2026 11:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 01/11/2026 05:20:00. 50 Premium Economy ticket for £29 per person are available. Travel duration is 18h 20m
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| Cikbus Elité | 20h 0m | 09:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 05:30 | Santiago, RM | Sur Bus Station | Premium Economy | £30 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 31/10/2026 09:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 01/11/2026 05:30:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 20h 0m
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| Pullman San Andres | 18h 30m | 12:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 06:30 | Santiago, RM | Terminal San Borja | Premium Economy | £32 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 31/10/2026 12:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 01/11/2026 06:30:00. 50 Premium Economy ticket for £32 per person are available. Travel duration is 18h 30m
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| Pullman Bus | 19h 15m | 23:15 | Antofagasta | Camus Coach Station | 18:30 | Santiago, RM | Terminal San Borja | First Class | £32 |
A Bus from Pullman Bus goes from Camus Coach Station, Antofagasta (Chile) at 31/10/2026 23:15:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 01/11/2026 18:30:00. 50 First Class ticket for £32 per person are available. Travel duration is 19h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Andimar | 19h 35m | 21:50 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:25 | Santiago, RM | Terminal San Borja | Economy | £26 |
A Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 01/11/2026 21:50:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 02/11/2026 17:25:00. 50 Economy ticket for £26 per person are available. Travel duration is 19h 35m
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| FlixBus | 18h 50m | 03:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 21:50 | Santiago, RM | Terminal San Borja | Economy | £27 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 01/11/2026 03:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 01/11/2026 21:50:00. 50 Economy ticket for £27 per person are available. Travel duration is 18h 50m
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| Cormar Bus | 18h 30m | 00:30 | Antofagasta | Camus Coach Station | 19:00 | Santiago, RM | Terminal San Borja | Premium Economy | £28 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 01/11/2026 00:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 01/11/2026 19:00:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 18h 30m
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| Pluss Chile | 17h 30m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Sur Bus Station | Premium Economy | £30 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 01/11/2026 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 01/11/2026 17:35:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 17h 30m
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| Pullman San Andres | 18h 30m | 12:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 06:30 | Santiago, RM | Terminal San Borja | Premium Economy | £32 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 01/11/2026 12:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 02/11/2026 06:30:00. 50 Premium Economy ticket for £32 per person are available. Travel duration is 18h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Andimar | 19h 35m | 21:50 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:25 | Santiago, RM | Terminal San Borja | Economy | £25 |
A Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 02/11/2026 21:50:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 03/11/2026 17:25:00. 50 Economy ticket for £25 per person are available. Travel duration is 19h 35m
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| Cormar Bus | 18h 30m | 00:30 | Antofagasta | Camus Coach Station | 19:00 | Santiago, RM | Terminal San Borja | Premium Economy | £28 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 02/11/2026 00:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 02/11/2026 19:00:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 18h 30m
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| Pluss Chile | 17h 30m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Sur Bus Station | Premium Economy | £30 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 02/11/2026 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 02/11/2026 17:35:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 17h 30m
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| Cikbus Elité | 20h 0m | 09:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 05:30 | Santiago, RM | Sur Bus Station | Premium Economy | £30 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 02/11/2026 09:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 03/11/2026 05:30:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 20h 0m
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| Pullman San Andres | 18h 30m | 12:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 06:30 | Santiago, RM | Terminal San Borja | Premium Economy | £32 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 02/11/2026 12:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 03/11/2026 06:30:00. 50 Premium Economy ticket for £32 per person are available. Travel duration is 18h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Andimar | 19h 35m | 21:50 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:25 | Santiago, RM | Terminal San Borja | Economy | £24 |
A Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 03/11/2026 21:50:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/11/2026 17:25:00. 50 Economy ticket for £24 per person are available. Travel duration is 19h 35m
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| FlixBus | 18h 50m | 03:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 21:50 | Santiago, RM | Terminal San Borja | Economy | £24 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 03/11/2026 03:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 03/11/2026 21:50:00. 50 Economy ticket for £24 per person are available. Travel duration is 18h 50m
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| Cormar Bus | 18h 30m | 00:30 | Antofagasta | Camus Coach Station | 19:00 | Santiago, RM | Terminal San Borja | Premium Economy | £27 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 03/11/2026 00:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 03/11/2026 19:00:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 18h 30m
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| Pluss Chile | 17h 30m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Sur Bus Station | Premium Economy | £30 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 03/11/2026 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 03/11/2026 17:35:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 17h 30m
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| Cikbus Elité | 20h 0m | 09:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 05:30 | Santiago, RM | Sur Bus Station | Premium Economy | £30 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 03/11/2026 09:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 04/11/2026 05:30:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 20h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Andimar | 18h 0m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 19:35 | Santiago, RM | Terminal San Borja | Economy | £22 |
A Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 04/11/2026 01:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/11/2026 19:35:00. 50 Economy ticket for £22 per person are available. Travel duration is 18h 0m
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| FlixBus | 18h 50m | 03:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 21:50 | Santiago, RM | Terminal San Borja | Economy | £23 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 04/11/2026 03:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/11/2026 21:50:00. 50 Economy ticket for £23 per person are available. Travel duration is 18h 50m
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| Cikbus Elité | 17h 25m | 01:15 | Antofagasta | Carlos Oviedo Cavada Bus Station | 18:40 | Santiago, RM | Terminal San Borja | Premium Economy | £26 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 04/11/2026 01:15:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/11/2026 18:40:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 17h 25m
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| Cormar Bus | 18h 30m | 00:30 | Antofagasta | Camus Coach Station | 19:00 | Santiago, RM | Terminal San Borja | Premium Economy | £28 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 04/11/2026 00:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/11/2026 19:00:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 18h 30m
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| Pluss Chile | 17h 30m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Sur Bus Station | Premium Economy | £30 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 04/11/2026 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 04/11/2026 17:35:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 17h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Andimar | 18h 0m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 19:35 | Santiago, RM | Terminal San Borja | Economy | £22 |
A Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/11/2026 01:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/11/2026 19:35:00. 50 Economy ticket for £22 per person are available. Travel duration is 18h 0m
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| Cormar Bus | 18h 30m | 00:30 | Antofagasta | Camus Coach Station | 19:00 | Santiago, RM | Terminal San Borja | Premium Economy | £28 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 05/11/2026 00:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/11/2026 19:00:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 18h 30m
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| Pluss Chile | 17h 30m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Sur Bus Station | Premium Economy | £30 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/11/2026 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/11/2026 17:35:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 17h 30m
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| Pullman San Andres | 18h 30m | 12:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 06:30 | Santiago, RM | Terminal San Borja | Premium Economy | £32 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/11/2026 12:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 06/11/2026 06:30:00. 50 Premium Economy ticket for £32 per person are available. Travel duration is 18h 30m
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| Cikbus Elité | 18h 40m | 03:10 | Antofagasta | Carlos Oviedo Cavada Bus Station | 21:50 | Santiago, RM | Terminal San Borja | First Class | £33 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/11/2026 03:10:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/11/2026 21:50:00. 50 First Class ticket for £33 per person are available. Travel duration is 18h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Andimar | 18h 0m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 19:35 | Santiago, RM | Terminal San Borja | Economy | £22 |
A Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/11/2026 01:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 06/11/2026 19:35:00. 50 Economy ticket for £22 per person are available. Travel duration is 18h 0m
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| FlixBus | 18h 50m | 03:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 21:50 | Santiago, RM | Terminal San Borja | Economy | £22 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/11/2026 03:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 06/11/2026 21:50:00. 50 Economy ticket for £22 per person are available. Travel duration is 18h 50m
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| Cormar Bus | 18h 30m | 00:30 | Antofagasta | Camus Coach Station | 19:00 | Santiago, RM | Terminal San Borja | Premium Economy | £28 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 06/11/2026 00:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 06/11/2026 19:00:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 18h 30m
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| Pullman Bus | 18h 40m | 12:50 | Antofagasta | Camus Coach Station | 07:30 | Santiago, RM | Terminal San Borja | Premium Economy | £29 |
A Bus from Pullman Bus goes from Camus Coach Station, Antofagasta (Chile) at 06/11/2026 12:50:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 07/11/2026 07:30:00. 50 Premium Economy ticket for £29 per person are available. Travel duration is 18h 40m
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| Cikbus Elité | 20h 0m | 09:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 05:30 | Santiago, RM | Sur Bus Station | Premium Economy | £30 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/11/2026 09:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 07/11/2026 05:30:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 20h 0m
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Best Price Offer: The price for the cheapest coach from Antofagasta to Santiago, RM is £22 on 04/11/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Antofagasta and Santiago, RM?
All facts for Antofagasta to Santiago, RM bus at a glance
Compare all coach operators like Pullman San Andres, Cikbus Elité and Pluss Chile that travel daily 116 times by bus from Antofagasta to Santiago, RM in one click. Book your Antofagasta to Santiago, RM bus ticket starting from £22!
| Cheapest Bus | £22 |
| Fastest Bus | 16h 40m |
| Earliest Coach | 00:30 |
| Latest Coach | 23:30 |
| Daily Bus Connections | 116 Ø |
| Distance | 1,089.2 km |
| Coach Companies | Pullman San Andres, Cikbus Elité, Pluss Chile, Pullman Bus, Andimar, Cormar Bus, FlixBus and Chile Bus |
What are the cheapest coach tickets from Antofagasta to Santiago, RM?
Every day, 116 buses from 8 coach companies leave Antofagasta for Santiago, RM. Check the table below to find the cheapest prices for coach tickets for this route, starting from 31/10/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Antofagasta to Santiago, RM
How to save money travelling from Antofagasta to Santiago, RM
Book the ticket from Antofagasta to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Antofagasta to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Antofagasta to Santiago, RM are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
Latest reviews for coach companies on the route Antofagasta - Santiago, RM
All bus stations and stops in Antofagasta and Santiago, RM
Here is a map with all coach stations in Antofagasta and Santiago, RM. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Antofagasta to Santiago, RM
FAQs for Antofagasta to Santiago, RM bus
How much does a Antofagasta Santiago, RM coach trip cost?
How much could I save by comparing buses from Antofagasta to Santiago, RM?
How many connections are available for the Antofagasta Santiago, RM route on average every day?
How long does a bus to Santiago, RM from Antofagasta take?
What time is the first bus from Antofagasta to Santiago, RM?
What time is the last coach from Antofagasta to Santiago, RM?
Which bus companies serve the Antofagasta Santiago, RM route?
Is there a direct bus between Antofagasta and Santiago, RM?
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What equipment is available for the Antofagasta Santiago, RM bus route?
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Available seat classes which are offered on the bus route Antofagasta to Santiago, RM
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
Best of the best: you will find the most comfortable accommodation to work or relax during your travel.
More bus routes to Antofagasta and to Santiago, RM
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