Which bus from Antofagasta to Santiago, RM is the cheapest?

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Which bus from Antofagasta to Santiago, RM is the best?

Check the bus schedule for Antofagasta to Santiago, RM. Here is a selection of the cheapest coach trips for the next days from bus operators like Pullman San Andres, Pluss Chile or Cikbus Elité. To see the full timetable for all coaches just use or search and compare.

today
£28
tomorrow
£25
Sunday
£26
Monday
£23
Tuesday
£22
Wednesday
£22
Thursday
£22

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cormar Bus 18h 20m 14:00 Antofagasta Camus Coach Station 08:20 Santiago, RM Terminal San Borja  Premium Economy £28
Pluss Chile 17h 30m 00:05 Antofagasta Carlos Oviedo Cavada Bus Station 17:35 Santiago, RM Sur Bus Station  Premium Economy £29
Pullman Bus 20h 0m 01:00 Antofagasta Camus Coach Station 21:00 Santiago, RM Terminal San Borja  First Class £29
Pullman San Andres 18h 30m 16:30 Antofagasta Carlos Oviedo Cavada Bus Station 11:00 Santiago, RM Terminal San Borja  Premium Economy £29
Nueva Andimar Vip 18h 0m 01:35 Antofagasta Carlos Oviedo Cavada Bus Station 19:35 Santiago, RM Terminal San Borja  Economy £29

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 19h 35m 22:00 Antofagasta Carlos Oviedo Cavada Bus Station 17:35 Santiago, RM Terminal San Borja  Economy £25
FlixBus 19h 35m 18:30 Antofagasta Carlos Oviedo Cavada Bus Station 14:05 Santiago, RM Terminal San Borja  Economy £25
Cikbus Elité 18h 50m 03:10 Antofagasta Carlos Oviedo Cavada Bus Station 22:00 Santiago, RM Sur Bus Station  Premium Economy £27
Pullman Bus 18h 30m 17:30 Antofagasta Carlos Oviedo Cavada Bus Station 12:00 Santiago, RM Terminal San Borja  Business £28
Pluss Chile 17h 30m 00:05 Antofagasta Carlos Oviedo Cavada Bus Station 17:35 Santiago, RM Sur Bus Station  Premium Economy £29

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 18h 0m 01:35 Antofagasta Carlos Oviedo Cavada Bus Station 19:35 Santiago, RM Terminal San Borja  Economy £26
Pullman Bus 20h 0m 01:00 Antofagasta Carlos Oviedo Cavada Bus Station 21:00 Santiago, RM Terminal San Borja  Business £28
Pluss Chile 17h 30m 00:05 Antofagasta Carlos Oviedo Cavada Bus Station 17:35 Santiago, RM Sur Bus Station  Premium Economy £29
Pullman San Andres 18h 30m 16:30 Antofagasta Carlos Oviedo Cavada Bus Station 11:00 Santiago, RM Terminal San Borja  Premium Economy £29
Cormar Bus 18h 20m 14:00 Antofagasta Camus Coach Station 08:20 Santiago, RM Terminal San Borja  Premium Economy £29

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 19h 35m 22:00 Antofagasta Carlos Oviedo Cavada Bus Station 17:35 Santiago, RM Terminal San Borja  Economy £23
FlixBus 19h 35m 18:30 Antofagasta Carlos Oviedo Cavada Bus Station 14:05 Santiago, RM Terminal San Borja  Economy £23
Pullman Bus 19h 15m 11:30 Antofagasta Camus Coach Station 06:45 Santiago, RM Terminal San Borja  First Class £24
Cikbus Elité 18h 50m 03:10 Antofagasta Carlos Oviedo Cavada Bus Station 22:00 Santiago, RM Sur Bus Station  Premium Economy £27
Cormar Bus 18h 20m 14:00 Antofagasta Camus Coach Station 08:20 Santiago, RM Terminal San Borja  Premium Economy £28

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 18h 0m 01:35 Antofagasta Carlos Oviedo Cavada Bus Station 19:35 Santiago, RM Terminal San Borja  Economy £22
FlixBus 19h 35m 18:30 Antofagasta Carlos Oviedo Cavada Bus Station 14:05 Santiago, RM Terminal San Borja  Economy £22
Pullman Bus 20h 0m 01:00 Antofagasta Camus Coach Station 21:00 Santiago, RM Terminal San Borja  First Class £24
Cikbus Elité 18h 50m 03:10 Antofagasta Carlos Oviedo Cavada Bus Station 22:00 Santiago, RM Sur Bus Station  Premium Economy £27
Pluss Chile 17h 30m 00:05 Antofagasta Carlos Oviedo Cavada Bus Station 17:35 Santiago, RM Sur Bus Station  Premium Economy £29

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 18h 0m 01:35 Antofagasta Carlos Oviedo Cavada Bus Station 19:35 Santiago, RM Terminal San Borja  Economy £22
Pullman Bus 20h 0m 01:00 Antofagasta Camus Coach Station 21:00 Santiago, RM Terminal San Borja  First Class £24
Cikbus Elité 18h 50m 03:10 Antofagasta Carlos Oviedo Cavada Bus Station 22:00 Santiago, RM Sur Bus Station  Premium Economy £27
Pluss Chile 17h 30m 00:05 Antofagasta Carlos Oviedo Cavada Bus Station 17:35 Santiago, RM Sur Bus Station  Premium Economy £29
Pullman San Andres 18h 30m 16:30 Antofagasta Carlos Oviedo Cavada Bus Station 11:00 Santiago, RM Terminal San Borja  Premium Economy £29

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 19h 35m 22:00 Antofagasta Carlos Oviedo Cavada Bus Station 17:35 Santiago, RM Terminal San Borja  Economy £22
FlixBus 19h 35m 18:30 Antofagasta Carlos Oviedo Cavada Bus Station 14:05 Santiago, RM Terminal San Borja  Economy £22
Cikbus Elité 18h 50m 03:10 Antofagasta Carlos Oviedo Cavada Bus Station 22:00 Santiago, RM Sur Bus Station  Premium Economy £27
Pluss Chile 17h 30m 00:05 Antofagasta Carlos Oviedo Cavada Bus Station 17:35 Santiago, RM Sur Bus Station  Premium Economy £29
Pullman Bus 20h 0m 01:00 Antofagasta Camus Coach Station 21:00 Santiago, RM Terminal San Borja  First Class £29

Best Price Offer: The price for the cheapest coach from Antofagasta to Santiago, RM is £22 on 24/03/2026. Flexible travellers save on ticket prices.


What is the best day and time to travel by bus between Antofagasta and Santiago, RM?

Here is the frequency of all coach connections from Antofagasta to Santiago, RM. See on which day of the week you have more travel options and what time you have more bus trips to choose from.
Tuesday is the busiest day, with more than 159 daily coaches from Antofagasta to Santiago, RM. Friday has instead the fewest connections, with only 85 daily coaches between Antofagasta and Santiago, RM.
The busiest time of the day is the Evening, with 367 coaches from Antofagasta to Santiago, RM, while Morning sees the fewest connections between Antofagasta and Santiago, RM, with 91 offers.

All facts for Antofagasta to Santiago, RM bus at a glance

Compare all coach operators like Pullman San Andres, Pluss Chile and Cikbus Elité that travel daily 119 times by bus from Antofagasta to Santiago, RM in one click. Book your Antofagasta to Santiago, RM bus ticket starting from £22!

Cheapest Bus £22
Fastest Bus 17h 5m
Earliest Coach 00:05
Latest Coach 23:59
Daily Bus Connections 119 Ø
Distance 1,089.2 km
Coach Companies Pullman San Andres, Pluss Chile, Cikbus Elité, Pullman Bus, Cormar Bus, FlixBus, Nueva Andimar Vip and Chile Bus

What are the cheapest coach tickets from Antofagasta to Santiago, RM?

Every day, 119 buses from 8 coach companies leave Antofagasta for Santiago, RM. Check the table below to find the cheapest prices for coach tickets for this route, starting from 20/03/2026 and for the following days. Make sure get the cheapest bus ticket!

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 16/03
Tuesday 17/03
Wednesday 18/03
Thursday 19/03
Friday 20/03
£28
Saturday 21/03
£28
Sunday 22/03
£26
Monday 23/03
£28
Tuesday 24/03
£22
Wednesday 25/03
£22
Thursday 26/03
£22
Friday 27/03
£24
Saturday 28/03
£22
Sunday 29/03
£23
Monday 30/03
£23
Tuesday 31/03
£29
Wednesday 01/04
£33
Thursday 02/04
£29
Friday 03/04
£28
Saturday 04/04
£28
Sunday 05/04
£31
Monday 06/04
£23
Tuesday 07/04
£22
Wednesday 08/04
£22
Thursday 09/04
£22
Friday 10/04
£24
Saturday 11/04
£22
Sunday 12/04

The cheapest time to travel from Antofagasta to Santiago, RM

See here on which day and which time of the day you can find the cheapest bus ticket from Antofagasta to Santiago, RM, for the next 30 days.
With a price starting from £22, Tuesday is the cheapest day for a coach from Antofagasta to Santiago, RM. Friday instead is the most expensive day with prices starting from £24.
Night is the cheapest day time for bus tickets from Antofagasta to Santiago, RM, with £22. Morning is the most expensive time of the day with prices starting from £24.

How to save money travelling from Antofagasta to Santiago, RM

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Antofagasta to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Antofagasta to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Antofagasta to Santiago, RM are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

All bus stations and stops in Antofagasta and Santiago, RM

Here is a map with all coach stations in Antofagasta and Santiago, RM. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Antofagasta to Santiago, RM? Compare all modes of transports from Antofagasta to Santiago, RM.

All you need to know when you travel by bus from Antofagasta to Santiago, RM

Check all information on comfort and services on the coaches from Antofagasta to Santiago, RM. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Antofagasta to Santiago, RM bus

How much does a Antofagasta Santiago, RM coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Antofagasta Santiago, RM bus trip is available from £22 and takes 18h 0m. Compare offers and save money!

How much could I save by comparing buses from Antofagasta to Santiago, RM?

This connection is offered by 8 companies with ticket prices ranging from £22 to £52. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Santiago, RM.

How many connections are available for the Antofagasta Santiago, RM route on average every day?

Each day, the bus route from Antofagasta to Santiago, RM is offered by roughly 119 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Santiago, RM from Antofagasta take?

The quickest coach from Antofagasta to Santiago, RM is provided by Cikbus Elité and takes 17h 5m. Coach tickets for this connection cost £30. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Antofagasta to Santiago, RM?

The earliest bus to Santiago, RM departs from Antofagasta at 00:05. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Antofagasta to Santiago, RM?

The latest bus to Santiago, RM departs from Antofagasta at 23:59. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Antofagasta Santiago, RM route?

Passengers looking to travel from Antofagasta to Santiago, RM can travel with Pullman San Andres, Pluss Chile and Cikbus Elité. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Antofagasta and Santiago, RM?

You can check all the direct connections between Antofagasta and Santiago, RM by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pullman San Andres, Pluss Chile and Cikbus Elité.

What can I take with me on the bus to Santiago, RM from Antofagasta?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Antofagasta Santiago, RM bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Antofagasta Santiago, RM bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Antofagasta to Santiago, RM on your planned travel date.

How does CheckMyBus find the best coach deals from Antofagasta to Santiago, RM?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 119 daily trips between Antofagasta and Santiago, RM. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Antofagasta to Santiago, RM?

Prices and availability for 119 trips between Antofagasta and Santiago, RM change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Antofagasta to Santiago, RM

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Antofagasta and to Santiago, RM

Here’s an overview of the most popular bus routes to Antofagasta and to Santiago, RM. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
Salta to Antofagasta bus Salta to Antofagasta bus
Bus Arica, AP to Antofagasta Bus Arica, AP to Antofagasta
Coach from Calama to Antofagasta Coach from Calama to Antofagasta
San Pedro de Atacama to Antofagasta coach San Pedro de Atacama to Antofagasta coach
Coach Temuco to Santiago, RM Coach Temuco to Santiago, RM
Coach to Santiago, RM from Pichilemu Coach to Santiago, RM from Pichilemu
Bus from Lonquimay to Santiago, RM Bus from Lonquimay to Santiago, RM
Bus Curacautin to Santiago, RM Bus Curacautin to Santiago, RM
Popular Airport Transfers to Antofagasta and to Santiago, RM
CheckMyBus › Coaches in Chile › Coach to Antofagasta › Coach to Santiago, RM

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