Which bus from Antofagasta to Santiago, RM is the best?
Check the bus schedule for Antofagasta to Santiago, RM. Here is a selection of the cheapest coach trips for the next days from bus operators like Pullman San Andres, Pluss Chile or Cikbus Elité. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Buses Norte Azul | 18h 5m | 21:15 | Antofagasta | Carlos Oviedo Cavada Bus Station | 15:20 | Santiago, RM | Terminal San Borja | Premium Economy | £25 |
A Bus from Buses Norte Azul goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 19/12/2025 21:15:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 20/12/2025 15:20:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 18h 5m
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| Cormar Bus | 18h 0m | 19:40 | Antofagasta | Camus Coach Station | 13:40 | Santiago, RM | Terminal San Borja | First Class | £32 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 19/12/2025 19:40:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 20/12/2025 13:40:00. 50 First Class ticket for £32 per person are available. Travel duration is 18h 0m
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| FlixBus | 19h 35m | 22:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Terminal San Borja | Economy | £32 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 19/12/2025 22:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 20/12/2025 17:35:00. 50 Economy ticket for £32 per person are available. Travel duration is 19h 35m
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| Pullman San Andres | 18h 30m | 23:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 18:00 | Santiago, RM | Terminal San Borja | Premium Economy | £33 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 19/12/2025 23:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 20/12/2025 18:00:00. 50 Premium Economy ticket for £33 per person are available. Travel duration is 18h 30m
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| Chile Bus | 18h 30m | 23:15 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:45 | Santiago, RM | Terminal San Borja | First Class | £33 |
A Bus from Chile Bus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 19/12/2025 23:15:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 20/12/2025 17:45:00. 50 First Class ticket for £33 per person are available. Travel duration is 18h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 18h 0m | 03:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 21:35 | Santiago, RM | Terminal San Borja | Economy | £25 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 20/12/2025 03:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 20/12/2025 21:35:00. 50 Economy ticket for £25 per person are available. Travel duration is 18h 0m
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| Cormar Bus | 17h 50m | 20:20 | Antofagasta | Camus Coach Station | 14:10 | Santiago, RM | Terminal San Borja | First Class | £32 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 20/12/2025 20:20:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 21/12/2025 14:10:00. 50 First Class ticket for £32 per person are available. Travel duration is 17h 50m
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| FlixBus | 18h 0m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 19:35 | Santiago, RM | Terminal San Borja | Economy | £32 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 20/12/2025 01:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 20/12/2025 19:35:00. 50 Economy ticket for £32 per person are available. Travel duration is 18h 0m
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| Pullman San Andres | 18h 30m | 23:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 18:00 | Santiago, RM | Terminal San Borja | Premium Economy | £33 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 20/12/2025 23:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 21/12/2025 18:00:00. 50 Premium Economy ticket for £33 per person are available. Travel duration is 18h 30m
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| Cikbus Elité | 21h 0m | 08:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 05:30 | Santiago, RM | Sur Bus Station | Premium Economy | £34 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 20/12/2025 08:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 21/12/2025 05:30:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 21h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cormar Bus | 18h 11m | 23:59 | Antofagasta | Camus Coach Station | 18:10 | Santiago, RM | Terminal San Borja | Premium Economy | £25 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 21/12/2025 23:59:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 22/12/2025 18:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 18h 11m
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| Nueva Andimar Vip | 18h 0m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 19:35 | Santiago, RM | Terminal San Borja | Economy | £25 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 21/12/2025 01:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 21/12/2025 19:35:00. 50 Economy ticket for £25 per person are available. Travel duration is 18h 0m
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| Pullman San Andres | 18h 30m | 23:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 18:00 | Santiago, RM | Terminal San Borja | Premium Economy | £33 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 21/12/2025 23:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 22/12/2025 18:00:00. 50 Premium Economy ticket for £33 per person are available. Travel duration is 18h 30m
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| Pluss Chile | 17h 30m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Sur Bus Station | Premium Economy | £34 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 21/12/2025 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 21/12/2025 17:35:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 17h 30m
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| Cikbus Elité | 21h 0m | 08:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 05:30 | Santiago, RM | Sur Bus Station | Premium Economy | £34 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 21/12/2025 08:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 22/12/2025 05:30:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 21h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 18h 0m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 19:35 | Santiago, RM | Terminal San Borja | Economy | £25 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 22/12/2025 01:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 22/12/2025 19:35:00. 50 Economy ticket for £25 per person are available. Travel duration is 18h 0m
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| Nueva Andimar Vip | 18h 0m | 03:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 21:35 | Santiago, RM | Terminal San Borja | Economy | £25 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 22/12/2025 03:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 22/12/2025 21:35:00. 50 Economy ticket for £25 per person are available. Travel duration is 18h 0m
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| Cormar Bus | 17h 10m | 21:05 | Antofagasta | Camus Coach Station | 14:15 | Santiago, RM | Terminal San Borja | First Class | £32 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 22/12/2025 21:05:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 23/12/2025 14:15:00. 50 First Class ticket for £32 per person are available. Travel duration is 17h 10m
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| Pullman San Andres | 18h 30m | 11:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 05:30 | Santiago, RM | Terminal San Borja | Premium Economy | £33 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 22/12/2025 11:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 23/12/2025 05:30:00. 50 Premium Economy ticket for £33 per person are available. Travel duration is 18h 30m
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| Pluss Chile | 17h 30m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Sur Bus Station | Premium Economy | £34 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 22/12/2025 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 22/12/2025 17:35:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 17h 30m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cormar Bus | 18h 11m | 23:59 | Antofagasta | Camus Coach Station | 18:10 | Santiago, RM | Terminal San Borja | Premium Economy | £27 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 23/12/2025 23:59:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 24/12/2025 18:10:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 18h 11m
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| FlixBus | 18h 0m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 19:35 | Santiago, RM | Terminal San Borja | Economy | £32 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 23/12/2025 01:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 23/12/2025 19:35:00. 50 Economy ticket for £32 per person are available. Travel duration is 18h 0m
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| Pullman San Andres | 18h 30m | 23:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 18:00 | Santiago, RM | Terminal San Borja | Premium Economy | £33 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 23/12/2025 23:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 24/12/2025 18:00:00. 50 Premium Economy ticket for £33 per person are available. Travel duration is 18h 30m
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| Pluss Chile | 17h 30m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Sur Bus Station | Premium Economy | £34 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 23/12/2025 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 23/12/2025 17:35:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 17h 30m
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| Cikbus Elité | 18h 50m | 03:10 | Antofagasta | Carlos Oviedo Cavada Bus Station | 22:00 | Santiago, RM | Sur Bus Station | Premium Economy | £34 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 23/12/2025 03:10:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 23/12/2025 22:00:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 18h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 19h 35m | 22:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Terminal San Borja | Economy | £25 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 24/12/2025 22:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 25/12/2025 17:35:00. 50 Economy ticket for £25 per person are available. Travel duration is 19h 35m
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| Cormar Bus | 17h 50m | 20:20 | Antofagasta | Camus Coach Station | 14:10 | Santiago, RM | Terminal San Borja | First Class | £32 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 24/12/2025 20:20:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 25/12/2025 14:10:00. 50 First Class ticket for £32 per person are available. Travel duration is 17h 50m
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| FlixBus | 18h 0m | 03:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 21:35 | Santiago, RM | Terminal San Borja | Economy | £32 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 24/12/2025 03:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 24/12/2025 21:35:00. 50 Economy ticket for £32 per person are available. Travel duration is 18h 0m
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| Pullman San Andres | 18h 30m | 23:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 18:00 | Santiago, RM | Terminal San Borja | Premium Economy | £33 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 24/12/2025 23:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 25/12/2025 18:00:00. 50 Premium Economy ticket for £33 per person are available. Travel duration is 18h 30m
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| Pluss Chile | 18h 20m | 10:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 04:50 | Santiago, RM | Sur Bus Station | Premium Economy | £34 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 24/12/2025 10:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 25/12/2025 04:50:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 18h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 18h 0m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 19:35 | Santiago, RM | Terminal San Borja | Economy | £25 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 25/12/2025 01:35:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 25/12/2025 19:35:00. 50 Economy ticket for £25 per person are available. Travel duration is 18h 0m
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| Cormar Bus | 18h 11m | 23:59 | Antofagasta | Camus Coach Station | 18:10 | Santiago, RM | Terminal San Borja | Premium Economy | £25 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 25/12/2025 23:59:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 26/12/2025 18:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 18h 11m
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| FlixBus | 19h 35m | 22:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Terminal San Borja | Economy | £32 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 25/12/2025 22:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 26/12/2025 17:35:00. 50 Economy ticket for £32 per person are available. Travel duration is 19h 35m
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| Pullman San Andres | 18h 30m | 23:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 18:00 | Santiago, RM | Terminal San Borja | Premium Economy | £33 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 25/12/2025 23:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 26/12/2025 18:00:00. 50 Premium Economy ticket for £33 per person are available. Travel duration is 18h 30m
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| Pluss Chile | 17h 30m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 17:35 | Santiago, RM | Sur Bus Station | Premium Economy | £34 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 25/12/2025 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 25/12/2025 17:35:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 17h 30m
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Best Price Offer: The price for the cheapest coach from Antofagasta to Santiago, RM is £22 on 07/01/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Antofagasta and Santiago, RM?
All facts for Antofagasta to Santiago, RM bus at a glance
Compare all coach operators like Pullman San Andres, Pluss Chile and Cikbus Elité that travel daily 68 times by bus from Antofagasta to Santiago, RM in one click. Book your Antofagasta to Santiago, RM bus ticket starting from £22!
| Cheapest Bus | £22 |
| Fastest Bus | 17h 5m |
| Earliest Coach | 10:00 |
| Latest Coach | 23:59 |
| Daily Bus Connections | 68 Ø |
| Distance | 1,089.2 km |
| Coach Companies | Pullman San Andres, Pluss Chile, Cikbus Elité, Pullman Bus, Nueva Andimar Vip, FlixBus, Cormar Bus, Chile Bus and Buses Norte Azul |
What are the cheapest coach tickets from Antofagasta to Santiago, RM?
Every day, 68 buses from 9 coach companies leave Antofagasta for Santiago, RM. Check the table below to find the cheapest prices for coach tickets for this route, starting from 19/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Antofagasta to Santiago, RM
How to save money travelling from Antofagasta to Santiago, RM
Book the ticket from Antofagasta to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Antofagasta to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Antofagasta to Santiago, RM are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Antofagasta and Santiago, RM
Here is a map with all coach stations in Antofagasta and Santiago, RM. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Antofagasta to Santiago, RM
FAQs for Antofagasta to Santiago, RM bus
How much does a Antofagasta Santiago, RM coach trip cost?
How much could I save by comparing buses from Antofagasta to Santiago, RM?
How many connections are available for the Antofagasta Santiago, RM route on average every day?
How long does a bus to Santiago, RM from Antofagasta take?
What time is the first bus from Antofagasta to Santiago, RM?
What time is the last coach from Antofagasta to Santiago, RM?
Which bus companies serve the Antofagasta Santiago, RM route?
Is there a direct bus between Antofagasta and Santiago, RM?
What can I take with me on the bus to Santiago, RM from Antofagasta?
What equipment is available for the Antofagasta Santiago, RM bus route?
How does CheckMyBus find the best coach deals from Antofagasta to Santiago, RM?
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Available seat classes which are offered on the bus route Antofagasta to Santiago, RM
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
Best of the best: you will find the most comfortable accommodation to work or relax during your travel.
More bus routes to Antofagasta and to Santiago, RM
- Bus Routes to Antofagasta
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- Bus Arica, AP to Antofagasta
- Bus to Antofagasta from Baquedano
- Coach from Calama to Antofagasta
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- Copiapó to Antofagasta coach
- La Calera to Antofagasta coach
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- Bus to Antofagasta from Los Vilos
- Coach to Antofagasta from Mejillones
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- Bus from Sierra Gorda to Antofagasta
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- Bus Routes to Santiago, RM
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