Which bus from Santa Cruz, LI to Santiago, RM is the best?
Check the bus schedule for Santa Cruz, LI to Santiago, RM. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus, Nueva Andimar Vip or Buses Jet Sur. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 2h 44m | 05:00 | Santa Cruz, LI | Central Bus Station | 07:44 | Santiago, RM | Sur Bus Station | Economy | £5 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, Santa Cruz, LI (Chile) at 05/12/2025 05:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/12/2025 07:44:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
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| Nueva Andimar Vip | 2h 44m | 05:50 | Santa Cruz, LI | Central Bus Station | 08:34 | Santiago, RM | Sur Bus Station | Economy | £5 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, Santa Cruz, LI (Chile) at 05/12/2025 05:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/12/2025 08:34:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
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| Nueva Andimar Vip | 2h 44m | 06:50 | Santa Cruz, LI | Central Bus Station | 09:34 | Santiago, RM | Sur Bus Station | Economy | £5 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, Santa Cruz, LI (Chile) at 05/12/2025 06:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/12/2025 09:34:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
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| Nueva Andimar Vip | 2h 44m | 07:30 | Santa Cruz, LI | Central Bus Station | 10:14 | Santiago, RM | Sur Bus Station | Economy | £5 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, Santa Cruz, LI (Chile) at 05/12/2025 07:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/12/2025 10:14:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
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| Nueva Andimar Vip | 2h 44m | 08:00 | Santa Cruz, LI | Central Bus Station | 10:44 | Santiago, RM | Sur Bus Station | Economy | £5 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, Santa Cruz, LI (Chile) at 05/12/2025 08:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/12/2025 10:44:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 2h 44m | 05:00 | Santa Cruz, LI | Central Bus Station | 07:44 | Santiago, RM | Sur Bus Station | Economy | £5 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, Santa Cruz, LI (Chile) at 06/12/2025 05:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 06/12/2025 07:44:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
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| Nueva Andimar Vip | 2h 44m | 05:50 | Santa Cruz, LI | Central Bus Station | 08:34 | Santiago, RM | Sur Bus Station | Economy | £5 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, Santa Cruz, LI (Chile) at 06/12/2025 05:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 06/12/2025 08:34:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
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| Nueva Andimar Vip | 2h 44m | 06:50 | Santa Cruz, LI | Central Bus Station | 09:34 | Santiago, RM | Sur Bus Station | Economy | £5 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, Santa Cruz, LI (Chile) at 06/12/2025 06:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 06/12/2025 09:34:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
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| Nueva Andimar Vip | 2h 44m | 07:30 | Santa Cruz, LI | Central Bus Station | 10:14 | Santiago, RM | Sur Bus Station | Economy | £5 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, Santa Cruz, LI (Chile) at 06/12/2025 07:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 06/12/2025 10:14:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
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| Nueva Andimar Vip | 2h 44m | 08:00 | Santa Cruz, LI | Central Bus Station | 10:44 | Santiago, RM | Sur Bus Station | Economy | £5 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, Santa Cruz, LI (Chile) at 06/12/2025 08:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 06/12/2025 10:44:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 2h 44m | 05:00 | Santa Cruz, LI | Central Bus Station | 07:44 | Santiago, RM | Sur Bus Station | Economy | £5 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, Santa Cruz, LI (Chile) at 08/12/2025 05:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 08/12/2025 07:44:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
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| Nueva Andimar Vip | 2h 44m | 05:50 | Santa Cruz, LI | Central Bus Station | 08:34 | Santiago, RM | Sur Bus Station | Economy | £5 |
A Bus from Nueva Andimar Vip goes from Central Bus Station, Santa Cruz, LI (Chile) at 08/12/2025 05:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 08/12/2025 08:34:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
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| Buses Jet Sur | 2h 0m | 07:00 | Santa Cruz, LI | Central Bus Station | 09:00 | Santiago, RM | Sur Bus Station | Premium Economy | £5 |
A Bus from Buses Jet Sur goes from Central Bus Station, Santa Cruz, LI (Chile) at 08/12/2025 07:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 08/12/2025 09:00:00. 50 Premium Economy ticket for £5 per person are available. Travel duration is 2h 0m
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| Buses Jet Sur | 3h 0m | 07:00 | Santa Cruz, LI | Central Bus Station | 10:00 | Santiago, RM | Sur Bus Station | Premium Economy | £5 |
A Bus from Buses Jet Sur goes from Central Bus Station, Santa Cruz, LI (Chile) at 08/12/2025 07:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 08/12/2025 10:00:00. 50 Premium Economy ticket for £5 per person are available. Travel duration is 3h 0m
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| Buses Transantin | 3h 15m | 08:10 | Santa Cruz, LI | Central Bus Station | 11:25 | Santiago, RM | Sur Bus Station | Premium Economy | £9 |
A Bus from Buses Transantin goes from Central Bus Station, Santa Cruz, LI (Chile) at 08/12/2025 08:10:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 08/12/2025 11:25:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 3h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 2h 44m | 06:50 | Santa Cruz, LI | Central Bus Station | 09:34 | Santiago, RM | Sur Bus Station | Economy | £4 |
A Bus from FlixBus goes from Central Bus Station, Santa Cruz, LI (Chile) at 11/12/2025 06:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 11/12/2025 09:34:00. 50 Economy ticket for £4 per person are available. Travel duration is 2h 44m
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| FlixBus | 2h 44m | 07:30 | Santa Cruz, LI | Central Bus Station | 10:14 | Santiago, RM | Sur Bus Station | Economy | £4 |
A Bus from FlixBus goes from Central Bus Station, Santa Cruz, LI (Chile) at 11/12/2025 07:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 11/12/2025 10:14:00. 50 Economy ticket for £4 per person are available. Travel duration is 2h 44m
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| FlixBus | 2h 44m | 14:00 | Santa Cruz, LI | Central Bus Station | 16:44 | Santiago, RM | Sur Bus Station | Economy | £4 |
A Bus from FlixBus goes from Central Bus Station, Santa Cruz, LI (Chile) at 11/12/2025 14:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 11/12/2025 16:44:00. 50 Economy ticket for £4 per person are available. Travel duration is 2h 44m
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| FlixBus | 2h 44m | 15:00 | Santa Cruz, LI | Central Bus Station | 17:44 | Santiago, RM | Sur Bus Station | Economy | £4 |
A Bus from FlixBus goes from Central Bus Station, Santa Cruz, LI (Chile) at 11/12/2025 15:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 11/12/2025 17:44:00. 50 Economy ticket for £4 per person are available. Travel duration is 2h 44m
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| FlixBus | 2h 44m | 15:30 | Santa Cruz, LI | Central Bus Station | 18:14 | Santiago, RM | Sur Bus Station | Economy | £4 |
A Bus from FlixBus goes from Central Bus Station, Santa Cruz, LI (Chile) at 11/12/2025 15:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 11/12/2025 18:14:00. 50 Economy ticket for £4 per person are available. Travel duration is 2h 44m
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Best Price Offer: The price for the cheapest coach from Santa Cruz, LI to Santiago, RM is £1 on 02/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Santa Cruz, LI and Santiago, RM?
All facts for Santa Cruz, LI to Santiago, RM bus at a glance
Compare all coach operators like FlixBus, Nueva Andimar Vip and Buses Jet Sur that travel daily 30 times by bus from Santa Cruz, LI to Santiago, RM in one click. Book your Santa Cruz, LI to Santiago, RM bus ticket starting from £1!
| Cheapest Bus | £1 |
| Fastest Bus | 2h 0m |
| Earliest Coach | 05:00 |
| Latest Coach | 18:00 |
| Daily Bus Connections | 30 Ø |
| Distance | 146.4 km |
| Coach Companies | FlixBus, Nueva Andimar Vip, Buses Jet Sur and Buses Transantin |
What are the cheapest coach tickets from Santa Cruz, LI to Santiago, RM?
Every day, 30 buses from 4 coach companies leave Santa Cruz, LI for Santiago, RM. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Santa Cruz, LI to Santiago, RM
How to save money travelling from Santa Cruz, LI to Santiago, RM
Book the ticket from Santa Cruz, LI to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Santa Cruz, LI to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Santa Cruz, LI to Santiago, RM are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Santa Cruz, LI and Santiago, RM
Here is a map with all coach stations in Santa Cruz, LI and Santiago, RM. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Santa Cruz, LI to Santiago, RM
FAQs for Santa Cruz, LI to Santiago, RM bus
How much does a Santa Cruz, LI Santiago, RM coach trip cost?
How much could I save by comparing buses from Santa Cruz, LI to Santiago, RM?
How many connections are available for the Santa Cruz, LI Santiago, RM route on average every day?
How long does a bus to Santiago, RM from Santa Cruz, LI take?
What time is the first bus from Santa Cruz, LI to Santiago, RM?
What time is the last coach from Santa Cruz, LI to Santiago, RM?
Which bus companies serve the Santa Cruz, LI Santiago, RM route?
Is there a direct bus between Santa Cruz, LI and Santiago, RM?
What can I take with me on the bus to Santiago, RM from Santa Cruz, LI?
What equipment is available for the Santa Cruz, LI Santiago, RM bus route?
Available seat classes which are offered on the bus route Santa Cruz, LI to Santiago, RM
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
More bus routes to Santa Cruz, LI and to Santiago, RM
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- Los Andes to Santiago, RM bus
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- Maitencillo to Santiago, RM bus
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- Coach Salamanca, CO to Santiago, RM
- Coach from San Carlos, BI to Santiago, RM
- Coach Talcahuano to Santiago, RM
- Coach Tongoy, CO to Santiago, RM
- Bus from Valparaíso (CL) to Santiago, RM

