Coach Santa Cruz, LI to Santiago, RM from £2

Which bus from Santa Cruz, LI to Santiago, RM is the best?

Check the bus schedule for Santa Cruz, LI to Santiago, RM. Here is a selection of the cheapest coach trips for the next days from bus operators like Andimar, Buses Transantin or Buses Jet Sur. To see the full timetable for all coaches just use or search and compare.

today

£5

tomorrow

£5

Sunday

£5

Monday

£5

Tuesday

£5

Wednesday

£5

Thursday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Andimar	2h 44m	05:00	Santa Cruz, LI	Central Bus Station	07:44	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 18/09/2026 05:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 18/09/2026 07:44:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	05:50	Santa Cruz, LI	Central Bus Station	08:34	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 18/09/2026 05:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 18/09/2026 08:34:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	06:50	Santa Cruz, LI	Central Bus Station	09:34	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 18/09/2026 06:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 18/09/2026 09:34:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	08:00	Santa Cruz, LI	Central Bus Station	10:44	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 18/09/2026 08:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 18/09/2026 10:44:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	09:05	Santa Cruz, LI	Central Bus Station	11:49	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 18/09/2026 09:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 18/09/2026 11:49:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Buses Jet Sur	3h 0m	06:35	Santa Cruz, LI	Central Bus Station	09:35	Santiago, RM	Sur Bus Station	Premium Economy	£5	A Bus from Buses Jet Sur goes from Central Bus Station, Santa Cruz, LI (Chile) at 19/09/2026 06:35:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 19/09/2026 09:35:00. 50 Premium Economy ticket for £5 per person are available. Travel duration is 3h 0m
Buses Jet Sur	3h 0m	07:40	Santa Cruz, LI	Central Bus Station	10:40	Santiago, RM	Sur Bus Station	Premium Economy	£5	A Bus from Buses Jet Sur goes from Central Bus Station, Santa Cruz, LI (Chile) at 19/09/2026 07:40:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 19/09/2026 10:40:00. 50 Premium Economy ticket for £5 per person are available. Travel duration is 3h 0m
Buses Transantin	3h 15m	08:10	Santa Cruz, LI	Central Bus Station	11:25	Santiago, RM	Sur Bus Station	Premium Economy	£5	A Bus from Buses Transantin goes from Central Bus Station, Santa Cruz, LI (Chile) at 19/09/2026 08:10:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 19/09/2026 11:25:00. 50 Premium Economy ticket for £5 per person are available. Travel duration is 3h 15m
Buses Transantin	3h 15m	09:10	Santa Cruz, LI	Central Bus Station	12:25	Santiago, RM	Sur Bus Station	Premium Economy	£5	A Bus from Buses Transantin goes from Central Bus Station, Santa Cruz, LI (Chile) at 19/09/2026 09:10:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 19/09/2026 12:25:00. 50 Premium Economy ticket for £5 per person are available. Travel duration is 3h 15m
Andimar	2h 44m	15:55	Santa Cruz, LI	Central Bus Station	18:39	Santiago, RM	Sur Bus Station	Economy	£6	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 19/09/2026 15:55:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 19/09/2026 18:39:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 44m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Andimar	3h 19m	13:00	Santa Cruz, LI	Central Bus Station	16:19	Santiago, RM	Terminal San Borja	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 20/09/2026 13:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 20/09/2026 16:19:00. 50 Economy ticket for £5 per person are available. Travel duration is 3h 19m
Andimar	3h 19m	15:00	Santa Cruz, LI	Central Bus Station	18:19	Santiago, RM	Terminal San Borja	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 20/09/2026 15:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 20/09/2026 18:19:00. 50 Economy ticket for £5 per person are available. Travel duration is 3h 19m
Andimar	2h 44m	14:00	Santa Cruz, LI	Central Bus Station	16:44	Santiago, RM	Sur Bus Station	Economy	£6	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 20/09/2026 14:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 20/09/2026 16:44:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	15:00	Santa Cruz, LI	Central Bus Station	17:44	Santiago, RM	Sur Bus Station	Economy	£6	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 20/09/2026 15:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 20/09/2026 17:44:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	15:55	Santa Cruz, LI	Central Bus Station	18:39	Santiago, RM	Sur Bus Station	Economy	£6	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 20/09/2026 15:55:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 20/09/2026 18:39:00. 50 Economy ticket for £6 per person are available. Travel duration is 2h 44m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Andimar	2h 44m	05:00	Santa Cruz, LI	Central Bus Station	07:44	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 21/09/2026 05:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 21/09/2026 07:44:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	05:50	Santa Cruz, LI	Central Bus Station	08:34	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 21/09/2026 05:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 21/09/2026 08:34:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	06:50	Santa Cruz, LI	Central Bus Station	09:34	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 21/09/2026 06:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 21/09/2026 09:34:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	07:30	Santa Cruz, LI	Central Bus Station	10:14	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 21/09/2026 07:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 21/09/2026 10:14:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	09:05	Santa Cruz, LI	Central Bus Station	11:49	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 21/09/2026 09:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 21/09/2026 11:49:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Andimar	2h 44m	05:00	Santa Cruz, LI	Central Bus Station	07:44	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 22/09/2026 05:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 22/09/2026 07:44:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	05:50	Santa Cruz, LI	Central Bus Station	08:34	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 22/09/2026 05:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 22/09/2026 08:34:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	06:50	Santa Cruz, LI	Central Bus Station	09:34	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 22/09/2026 06:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 22/09/2026 09:34:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	07:30	Santa Cruz, LI	Central Bus Station	10:14	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 22/09/2026 07:30:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 22/09/2026 10:14:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	09:05	Santa Cruz, LI	Central Bus Station	11:49	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 22/09/2026 09:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 22/09/2026 11:49:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Andimar	2h 44m	05:00	Santa Cruz, LI	Central Bus Station	07:44	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 23/09/2026 05:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 23/09/2026 07:44:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	05:50	Santa Cruz, LI	Central Bus Station	08:34	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 23/09/2026 05:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 23/09/2026 08:34:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	06:50	Santa Cruz, LI	Central Bus Station	09:34	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 23/09/2026 06:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 23/09/2026 09:34:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	08:00	Santa Cruz, LI	Central Bus Station	10:44	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 23/09/2026 08:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 23/09/2026 10:44:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m
Andimar	2h 44m	09:05	Santa Cruz, LI	Central Bus Station	11:49	Santiago, RM	Sur Bus Station	Economy	£5	A Bus from Andimar goes from Central Bus Station, Santa Cruz, LI (Chile) at 23/09/2026 09:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 23/09/2026 11:49:00. 50 Economy ticket for £5 per person are available. Travel duration is 2h 44m

Best Price Offer: The price for the cheapest coach from Santa Cruz, LI to Santiago, RM is £2 on 14/09/2026. Flexible travellers save on ticket prices.

What is the best day and time to travel by bus between Santa Cruz, LI and Santiago, RM?

Here is the frequency of all coach connections from Santa Cruz, LI to Santiago, RM. See on which day of the week you have more travel options and what time you have more bus trips to choose from.

Saturday is the busiest day, with more than 43 daily coaches from Santa Cruz, LI to Santiago, RM. Sunday has instead the fewest connections, with only 8 daily coaches between Santa Cruz, LI and Santiago, RM.

The busiest time of the day is the Afternoon, with 69 coaches from Santa Cruz, LI to Santiago, RM, while Evening sees the fewest connections between Santa Cruz, LI and Santiago, RM, with 11 offers.

All facts for Santa Cruz, LI to Santiago, RM bus at a glance

Compare all coach operators like Andimar, Buses Transantin and Buses Jet Sur that travel daily 21 times by bus from Santa Cruz, LI to Santiago, RM in one click. Book your Santa Cruz, LI to Santiago, RM bus ticket starting from £2!

Cheapest Bus	£2
Fastest Bus	2h 44m
Earliest Coach	05:00
Latest Coach	18:00
Daily Bus Connections	21 Ø
Distance	146.4 km
Coach Companies	Andimar, Buses Transantin and Buses Jet Sur

What are the cheapest coach tickets from Santa Cruz, LI to Santiago, RM?

Every day, 21 buses from 3 coach companies leave Santa Cruz, LI for Santiago, RM. Check the table below to find the cheapest prices for coach tickets for this route, starting from 18/09/2026 and for the following days. Make sure get the cheapest bus ticket!

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 14/09

Tuesday 15/09

Wednesday 16/09

Thursday 17/09

Friday 18/09

£5

Saturday 19/09

£5

Sunday 20/09

£5

Monday 21/09

£5

Tuesday 22/09

£5

Wednesday 23/09

£5

Thursday 24/09

Friday 25/09

£5

Saturday 26/09

£6

Sunday 27/09

£7

Monday 28/09

£5

Tuesday 29/09

£5

Wednesday 30/09

£6

Thursday 01/10

Friday 02/10

Saturday 03/10

£4

Sunday 04/10

£5

Monday 05/10

£5

Tuesday 06/10

£5

Wednesday 07/10

£5

Thursday 08/10

£5

Friday 09/10

£6

Saturday 10/10

£6

Sunday 11/10

The cheapest time to travel from Santa Cruz, LI to Santiago, RM

See here on which day and which time of the day you can find the cheapest bus ticket from Santa Cruz, LI to Santiago, RM, for the next 30 days.

With a price starting from £4, Saturday is the cheapest day for a coach from Santa Cruz, LI to Santiago, RM. Sunday instead is the most expensive day with prices starting from £5.

Night is the cheapest day time for bus tickets from Santa Cruz, LI to Santiago, RM, with £4. Morning is the most expensive time of the day with prices starting from £5.

How to save money travelling from Santa Cruz, LI to Santiago, RM

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Santa Cruz, LI to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Santa Cruz, LI to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Santa Cruz, LI to Santiago, RM are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

All bus stations and stops in Santa Cruz, LI and Santiago, RM

Here is a map with all coach stations in Santa Cruz, LI and Santiago, RM. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Central Bus Station

Av. Rafael Casanova 504

Shell Gas Station

Copec Gas Station

Hospital

La Gloria

Terminal San Borja

San Francisco de Borja 198-180

Los Héroes Station

Tucapel Jiménez 22

Baquedano

Pl. Baquedano

Porto Seguro Coach Station

Sur Bus Station

Av Libertador Bernardo O'Higgins 3850

All you need to know when you travel by bus from Santa Cruz, LI to Santiago, RM

Check all information on comfort and services on the coaches from Santa Cruz, LI to Santiago, RM. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Santa Cruz, LI to Santiago, RM bus

How much does a Santa Cruz, LI Santiago, RM coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Santa Cruz, LI Santiago, RM bus trip is available from £2 and takes 2h 44m. Compare offers and save money!

How much could I save by comparing buses from Santa Cruz, LI to Santiago, RM?

This connection is offered by 3 companies with ticket prices ranging from £2 to £9. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Santiago, RM.

How many connections are available for the Santa Cruz, LI Santiago, RM route on average every day?

Each day, the bus route from Santa Cruz, LI to Santiago, RM is offered by roughly 21 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Santiago, RM from Santa Cruz, LI take?

The quickest coach from Santa Cruz, LI to Santiago, RM is provided by Andimar and takes 2h 44m. Coach tickets for this connection cost £5. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Santa Cruz, LI to Santiago, RM?

The earliest bus to Santiago, RM departs from Santa Cruz, LI at 05:00. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Santa Cruz, LI to Santiago, RM?

The latest bus to Santiago, RM departs from Santa Cruz, LI at 18:00. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Santa Cruz, LI Santiago, RM route?

Passengers looking to travel from Santa Cruz, LI to Santiago, RM can travel with Andimar, Buses Transantin and Buses Jet Sur. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Santa Cruz, LI and Santiago, RM?

You can check all the direct connections between Santa Cruz, LI and Santiago, RM by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Andimar, Buses Transantin and Buses Jet Sur.

What can I take with me on the bus to Santiago, RM from Santa Cruz, LI?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Santa Cruz, LI Santiago, RM bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Santa Cruz, LI Santiago, RM bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santa Cruz, LI to Santiago, RM on your planned travel date.

How does CheckMyBus find the best coach deals from Santa Cruz, LI to Santiago, RM?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 21 daily trips between Santa Cruz, LI and Santiago, RM. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santa Cruz, LI to Santiago, RM?

Prices and availability for 21 trips between Santa Cruz, LI and Santiago, RM change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santa Cruz, LI to Santiago, RM

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Santa Cruz, LI and to Santiago, RM

Here’s an overview of the most popular bus routes to Santa Cruz, LI and to Santiago, RM. Simply click on the connection of your choice, and you’ll find all the details about your bus route!