How to get from Antofagasta to Santiago, RM

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What is the best way to travel from Antofagasta to Santiago, RM?

Looking for a trip? Check and compare all the available Flights and Buses to Santiago, RM from Antofagasta. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 11 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
17h 10m
£25
£33
155
Flight
1h 47m
£56
£88
101

What is the cheapest way to reach Santiago, RM from Antofagasta?

You can reach Santiago, RM with just £25 by taking a Bus from Ramos Cholele, but there are many more cheap offers: we have selected the best ones for you for the next few days here.

Wednesday
from £33
Thursday
from £25
Friday
from £31
Saturday
from £33
Sunday
from £31
Monday
from £30
Tuesday
from £30

    Cheapest Buses Wednesday

  • Cormar Bus
    17h 10m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    06:10
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    £33
  • Pullman San Andres
    18h 30m
    0
    15:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    10:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £34
  • Pullman Bus
    19h 0m
    0
    23:30
    Antofagasta
    Camus Coach Station
    18:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £35
  • Pluss Chile
    17h 30m
    0
    15:16
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    08:46
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £35
  • Cikbus Elité
    18h 15m
    0
    22:15
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    16:30
    Santiago, RM
    Terminal San Borja
    0
    Cikbus Elité
    Business
    £37
  • Cheapest Flights Wednesday

  • LATAM Brasil
    1h 47m
    0
    23:59
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:46
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £70
  • LAN Airlines
    1h 47m
    0
    23:15
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:02
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £92
  • JetSmart
    1h 54m
    0
    15:07
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    17:01
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £93
  • LAN Perú
    1h 48m
    0
    10:41
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:29
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £116
  • Sky Airline
    1h 51m
    0
    20:55
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    22:46
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £117

    Cheapest Buses Thursday

  • Ramos Cholele
    18h 0m
    0
    14:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    08:30
    Santiago, RM
    Terminal San Borja
    0
    Ramos Cholele
    First Class
    £25
  • Cormar Bus
    18h 10m
    0
    14:10
    Antofagasta
    Camus Coach Station
    08:20
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £31
  • Pullman San Andres
    18h 30m
    0
    15:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    10:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £34
  • Chile Bus
    19h 1m
    0
    23:59
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:00
    Santiago, RM
    Terminal San Borja
    0
    Chile Bus
    Premium Economy
    £34
  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £35
  • Cheapest Flights Thursday

  • LATAM Brasil
    1h 47m
    0
    23:22
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:09
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £79
  • LAN Airlines
    1h 47m
    0
    23:22
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:09
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £82
  • Sky Airline
    2h 1m
    0
    22:37
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    00:38
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £83
  • LAN Perú
    1h 48m
    0
    08:29
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:17
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £98
  • JetSmart
    9h 44m
    0
    11:41
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    21:25
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £112

    Cheapest Buses Friday

  • Pullman San Andres
    18h 30m
    0
    23:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    18:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £31
  • Cormar Bus
    17h 50m
    0
    20:20
    Antofagasta
    Camus Coach Station
    14:10
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    £33
  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £35
  • Cikbus Elité
    21h 0m
    0
    08:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    05:30
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    £35
  • Nueva Andimar Vip
    18h 0m
    0
    03:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:35
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    £37
  • Cheapest Flights Friday

  • LATAM Brasil
    1h 47m
    0
    23:33
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:20
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £92
  • LAN Airlines
    1h 47m
    0
    23:33
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:20
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £92
  • LAN Perú
    1h 48m
    0
    11:00
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:48
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £108
  • Sky Airline
    2h 1m
    0
    08:58
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:59
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £115
  • JetSmart
    1h 52m
    0
    20:58
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    22:50
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £125

    Cheapest Buses Saturday

  • Cormar Bus
    17h 50m
    0
    20:20
    Antofagasta
    Camus Coach Station
    14:10
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    £33
  • Pullman San Andres
    18h 30m
    0
    15:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    10:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £34
  • Nueva Andimar Vip
    18h 0m
    0
    03:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:35
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    £34
  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £35
  • Cikbus Elité
    21h 0m
    0
    08:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    05:30
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    £35
  • Cheapest Flights Saturday

  • LAN Airlines
    11h 27m
    0
    09:13
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    20:40
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £74
  • LATAM Brasil
    1h 47m
    0
    19:20
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    21:07
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £76
  • JetSmart
    1h 52m
    0
    20:58
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    22:50
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £76
  • LAN Perú
    1h 47m
    0
    19:20
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    21:07
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £76
  • Sky Airline
    1h 51m
    0
    18:19
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    20:10
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £91

    Cheapest Buses Sunday

  • Pullman San Andres
    18h 30m
    0
    23:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    18:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £31
  • Cormar Bus
    17h 50m
    0
    20:20
    Antofagasta
    Camus Coach Station
    14:10
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    £33
  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £35
  • Cikbus Elité
    21h 0m
    0
    08:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    05:30
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    £35
  • Nueva Andimar Vip
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    £38
  • Cheapest Flights Sunday

  • LATAM Brasil
    1h 47m
    0
    23:59
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:46
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £56
  • LAN Airlines
    1h 47m
    0
    23:59
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:46
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £56
  • Sky Airline
    2h 1m
    0
    22:47
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    00:48
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £65
  • LAN Perú
    1h 48m
    0
    07:17
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:05
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £76
  • JetSmart
    12h 4m
    0
    21:51
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:55
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £120

    Cheapest Buses Monday

  • FlixBus
    18h 0m
    0
    03:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:35
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    £30
  • Pullman San Andres
    18h 30m
    0
    23:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    18:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £31
  • Nueva Andimar Vip
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    £32
  • Cormar Bus
    17h 10m
    0
    21:05
    Antofagasta
    Camus Coach Station
    14:15
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    £33
  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £35
  • Cheapest Flights Monday

  • LAN Perú
    1h 48m
    0
    07:14
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:02
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £63
  • LAN Airlines
    1h 47m
    0
    22:53
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    00:40
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £63
  • LATAM Brasil
    1h 48m
    0
    07:14
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:02
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £65
  • Sky Airline
    2h 1m
    0
    21:15
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    23:16
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £73
  • JetSmart
    1h 54m
    0
    00:14
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    02:08
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £76

    Cheapest Buses Tuesday

  • Nueva Andimar Vip
    18h 0m
    0
    03:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:35
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    £30
  • FlixBus
    18h 0m
    0
    03:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:35
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    £30
  • Cormar Bus
    18h 10m
    0
    14:10
    Antofagasta
    Camus Coach Station
    08:20
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £31
  • Pullman San Andres
    18h 30m
    0
    15:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    10:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £34
  • Chile Bus
    18h 15m
    0
    23:15
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:30
    Santiago, RM
    Terminal San Borja
    0
    Chile Bus
    First Class
    £34
  • Cheapest Flights Tuesday

  • LAN Airlines
    25h 20m
    0
    09:18
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:38
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £81
  • Sky Airline
    2h 1m
    0
    08:42
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:43
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £91
  • LATAM Brasil
    1h 48m
    0
    07:50
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:38
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £95
  • LAN Perú
    1h 48m
    0
    07:50
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:38
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £107
  • JetSmart
    11h 18m
    0
    09:46
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    21:04
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £118

What are the fastest trips from Antofagasta to Santiago, RM?

You can get to Santiago, RM from Antofagasta in just 1h 47m with a Flight from LATAM Brasil. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.

Wednesday
from 1h 47m
Thursday
from 1h 47m
Friday
from 1h 47m
Saturday
from 1h 47m
Sunday
from 1h 47m
Monday
from 1h 47m
Tuesday
from 1h 48m

    Fastest Flights Wednesday

  • LATAM Brasil
    1h 47m
    0
    23:59
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:46
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £70
  • LAN Airlines
    1h 47m
    0
    23:15
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:02
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £92
  • LAN Perú
    1h 48m
    0
    10:41
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:29
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £116
  • Sky Airline
    1h 51m
    0
    20:55
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    22:46
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £117
  • JetSmart
    1h 54m
    0
    15:07
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    17:01
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £93
  • Fastest Buses Wednesday

  • Cormar Bus
    17h 10m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    06:10
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    £33
  • Pluss Chile
    17h 30m
    0
    15:16
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    08:46
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £35
  • Cikbus Elité
    18h 15m
    0
    22:15
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    16:30
    Santiago, RM
    Terminal San Borja
    0
    Cikbus Elité
    Business
    £37
  • Pullman San Andres
    18h 30m
    0
    15:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    10:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £34
  • Pullman Bus
    19h 0m
    0
    23:30
    Antofagasta
    Camus Coach Station
    18:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £35

    Fastest Flights Thursday

  • LATAM Brasil
    1h 47m
    0
    23:22
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:09
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £79
  • LAN Airlines
    1h 47m
    0
    23:22
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:09
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £82
  • LAN Perú
    1h 48m
    0
    08:29
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:17
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £98
  • Sky Airline
    2h 1m
    0
    22:37
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    00:38
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £83
  • JetSmart
    9h 44m
    0
    11:41
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    21:25
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £112
  • Fastest Buses Thursday

  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £35
  • Ramos Cholele
    18h 0m
    0
    14:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    08:30
    Santiago, RM
    Terminal San Borja
    0
    Ramos Cholele
    First Class
    £25
  • Cormar Bus
    18h 10m
    0
    14:10
    Antofagasta
    Camus Coach Station
    08:20
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £31
  • Pullman San Andres
    18h 30m
    0
    15:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    10:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £34
  • Chile Bus
    19h 1m
    0
    23:59
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:00
    Santiago, RM
    Terminal San Borja
    0
    Chile Bus
    Premium Economy
    £34

    Fastest Flights Friday

  • LATAM Brasil
    1h 47m
    0
    23:33
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:20
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £92
  • LAN Airlines
    1h 47m
    0
    23:33
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:20
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £92
  • LAN Perú
    1h 48m
    0
    11:00
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:48
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £108
  • JetSmart
    1h 52m
    0
    20:58
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    22:50
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £125
  • Sky Airline
    2h 1m
    0
    08:58
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:59
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £115
  • Fastest Buses Friday

  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £35
  • Cormar Bus
    17h 50m
    0
    20:20
    Antofagasta
    Camus Coach Station
    14:10
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    £33
  • Nueva Andimar Vip
    18h 0m
    0
    03:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:35
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    £37
  • Pullman San Andres
    18h 30m
    0
    23:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    18:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £31
  • Cikbus Elité
    21h 0m
    0
    08:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    05:30
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    £35

    Fastest Flights Saturday

  • LATAM Brasil
    1h 47m
    0
    19:20
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    21:07
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £76
  • LAN Perú
    1h 47m
    0
    19:20
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    21:07
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £76
  • Sky Airline
    1h 51m
    0
    18:19
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    20:10
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £91
  • JetSmart
    1h 52m
    0
    20:58
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    22:50
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £76
  • LAN Airlines
    11h 27m
    0
    09:13
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    20:40
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £74
  • Fastest Buses Saturday

  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £35
  • Cormar Bus
    17h 50m
    0
    20:20
    Antofagasta
    Camus Coach Station
    14:10
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    £33
  • Nueva Andimar Vip
    18h 0m
    0
    03:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:35
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    £34
  • Pullman San Andres
    18h 30m
    0
    15:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    10:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £34
  • Cikbus Elité
    21h 0m
    0
    08:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    05:30
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    £35

    Fastest Flights Sunday

  • LATAM Brasil
    1h 47m
    0
    23:59
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:46
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £56
  • LAN Airlines
    1h 47m
    0
    23:59
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    01:46
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £56
  • LAN Perú
    1h 48m
    0
    07:17
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:05
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £76
  • Sky Airline
    2h 1m
    0
    22:47
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    00:48
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £65
  • JetSmart
    12h 4m
    0
    21:51
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:55
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £120
  • Fastest Buses Sunday

  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £35
  • Cormar Bus
    17h 50m
    0
    20:20
    Antofagasta
    Camus Coach Station
    14:10
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    £33
  • Nueva Andimar Vip
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    £38
  • Pullman San Andres
    18h 30m
    0
    23:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    18:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £31
  • Cikbus Elité
    21h 0m
    0
    08:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    05:30
    Santiago, RM
    Sur Bus Station
    0
    Cikbus Elité
    Premium Economy
    £35

    Fastest Flights Monday

  • LAN Airlines
    1h 47m
    0
    22:53
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    00:40
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £63
  • LAN Perú
    1h 48m
    0
    07:14
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:02
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £63
  • LATAM Brasil
    1h 48m
    0
    07:14
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:02
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £65
  • JetSmart
    1h 54m
    0
    00:14
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    02:08
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £76
  • Sky Airline
    2h 1m
    0
    21:15
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    23:16
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £73
  • Fastest Buses Monday

  • Cormar Bus
    17h 10m
    0
    21:05
    Antofagasta
    Camus Coach Station
    14:15
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    First Class
    £33
  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £35
  • FlixBus
    18h 0m
    0
    03:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:35
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    £30
  • Nueva Andimar Vip
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    £32
  • Pullman San Andres
    18h 30m
    0
    23:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    18:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £31

    Fastest Flights Tuesday

  • LATAM Brasil
    1h 48m
    0
    07:50
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:38
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £95
  • LAN Perú
    1h 48m
    0
    07:50
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:38
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £107
  • Sky Airline
    2h 1m
    0
    08:42
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:43
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £91
  • JetSmart
    11h 18m
    0
    09:46
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    21:04
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £118
  • LAN Airlines
    25h 20m
    0
    09:18
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:38
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £81
  • Fastest Buses Tuesday

  • Nueva Andimar Vip
    18h 0m
    0
    03:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:35
    Santiago, RM
    Terminal San Borja
    0
    Nueva Andimar Vip
    Economy
    £30
  • FlixBus
    18h 0m
    0
    03:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:35
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    £30
  • Cormar Bus
    18h 10m
    0
    14:10
    Antofagasta
    Camus Coach Station
    08:20
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £31
  • Chile Bus
    18h 15m
    0
    23:15
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:30
    Santiago, RM
    Terminal San Borja
    0
    Chile Bus
    First Class
    £34
  • Pullman San Andres
    18h 30m
    0
    15:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    10:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £34
Here you will find all operators and timetables for a Bus from Antofagasta to Santiago, RM

What are the most popular stations in Antofagasta and Santiago, RM?

In Antofagasta, you will usually depart from Carlos Oviedo Cavada Bus Station, Camus Coach Station or Maipú, while in Santiago, RM you will be arriving at Terminal Alameda, Terminal San Borja or Sur Bus Station, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Santiago, RM from Antofagasta? With 10 connections between 11 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Antofagasta and Santiago, RM, you can pay as low as £25 with a Bus from Ramos Cholele.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from LATAM Brasil: you will get to Santiago, RM in just 1h 47m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Antofagasta and Santiago, RM are Cormar Bus, Pullman San Andres and LATAM Brasil, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Antofagasta and Santiago, RM is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from La Negra or to Lo Prado, and look at flights from Andrés Sabella Gálvez, Antofagasta Airport, and landing at Santiago de Chile Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Antofagasta to Santiago, RM?

The most popular companies between Antofagasta and Santiago, RM, are Cormar Bus, Pullman San Andres and LATAM Brasil. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: Cormar Bus, Pullman San Andres, Pluss Chile and 6 more.

Airlines: LATAM Brasil, LAN Airlines, JetSmart and 2 more.

All you need to know when you travel from Antofagasta to Santiago, RM

Check all information on comfort and services on all modes of transports from Antofagasta to Santiago, RM. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Antofagasta to Santiago, RM

How can I reach Santiago, RM from Antofagasta?

Every day, there are on average 10 connections between Flight and Bus, with which you can get to Santiago, RM from Antofagasta.

How far is Santiago, RM from Antofagasta?

The distance between Antofagasta and Santiago, RM is 1,089.2 km.

What is the most ecofriendly mode of transport between Antofagasta and Santiago, RM?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 29 kgs of CO2, a train 38 kgs, a car 185 kgs, and a flight 268 kgs.

What is the cheapest mode of transport from Antofagasta to Santiago, RM?

You can get to Santiago, RM with just £25 by taking a Bus from Ramos Cholele.

What is the fastest way to get from Antofagasta to Santiago, RM?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Santiago, RM in just 1h 47m with a Flight from LATAM Brasil.

More routes to Antofagasta and to Santiago, RM

Looking for more options? Here you can see the most popular routes to Antofagasta and to Santiago, RM. Simply click on a connection, and you’ll find all the details about the route!

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