How to get from Antofagasta to Santiago, RM

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What is the best way to travel from Antofagasta to Santiago, RM?

Looking for a trip? Check and compare all the available Buses and Flights to Santiago, RM from Antofagasta. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 10 available companies to find your perfect trip!
Flight is the cheapest and fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
17h 30m
£24
£27
109
Flight
1h 53m
£17
£57
77

What is the cheapest way to reach Santiago, RM from Antofagasta?

You can reach Santiago, RM with just £17 by taking a Flight from JetSmart, but there are many more cheap offers: we have selected the best ones for you for the next few days here.

Friday
from £27
Saturday
from £26
Sunday
from £27
Monday
from £17
Tuesday
from £23
Wednesday
from £24
Thursday
from £24

    Cheapest Buses Friday

  • Pullman San Andres
    18h 30m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    07:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £27
  • Andimar
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Andimar
    Economy
    £28
  • FlixBus
    18h 50m
    0
    03:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:50
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    £28
  • Pluss Chile
    18h 15m
    0
    01:31
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:46
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £29
  • Cormar Bus
    19h 0m
    0
    13:50
    Antofagasta
    Camus Coach Station
    08:50
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £29
  • Cheapest Flights Friday

  • Sky Airline
    1h 53m
    0
    08:50
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:43
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £36
  • JetSmart
    21h 51m
    0
    21:06
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    18:57
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £95
  • JetSmart
    10h 13m
    0
    21:06
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    07:19
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £101
  • LAN Airlines
    23h 8m
    0
    19:49
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    18:57
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £107
  • LAN Airlines
    11h 30m
    0
    19:49
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    07:19
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £113

    Cheapest Buses Saturday

  • Andimar
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Andimar
    Economy
    £26
  • Pullman Bus
    20h 0m
    0
    01:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £27
  • Pullman San Andres
    18h 30m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    07:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £28
  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £29
  • Cormar Bus
    19h 0m
    0
    13:50
    Antofagasta
    Camus Coach Station
    08:50
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £29
  • Cheapest Flights Saturday

  • LAN Airlines
    7h 27m
    0
    11:30
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    18:57
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £93
  • LATAM Brasil
    7h 27m
    0
    11:30
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    18:57
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £94
  • LAN Airlines
    5h 53m
    0
    11:30
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    17:23
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £100
  • LATAM Brasil
    5h 53m
    0
    11:30
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    17:23
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £102
  • JetSmart
    1h 57m
    0
    20:53
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    22:50
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £151

    Cheapest Buses Sunday

  • Pullman San Andres
    18h 30m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    07:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £27
  • Pullman Bus
    19h 15m
    0
    11:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    06:45
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £27
  • Cormar Bus
    18h 25m
    0
    23:45
    Antofagasta
    Camus Coach Station
    18:10
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £28
  • Andimar
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Andimar
    Economy
    £28
  • FlixBus
    18h 50m
    0
    03:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:50
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    £28

    Cheapest Flights Monday

  • JetSmart
    1h 57m
    0
    07:48
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:45
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £17
  • JetSmart
    1h 57m
    0
    12:31
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    14:28
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £17
  • Sky Airline
    1h 53m
    0
    07:50
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:43
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £18
  • Sky Airline
    1h 53m
    0
    09:56
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:49
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £18
  • LAN Airlines
    1h 57m
    0
    08:47
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:44
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £20
  • Cheapest Buses Monday

  • Pullman Bus
    19h 15m
    0
    11:30
    Antofagasta
    Camus Coach Station
    06:45
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £24
  • Andimar
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Andimar
    Economy
    £25
  • Pullman San Andres
    18h 30m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    07:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £27
  • Cormar Bus
    18h 25m
    0
    23:45
    Antofagasta
    Camus Coach Station
    18:10
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £28
  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £29

    Cheapest Flights Tuesday

  • JetSmart
    1h 57m
    0
    17:05
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    19:02
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £23
  • Sky Airline
    1h 53m
    0
    08:40
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:33
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £32
  • LATAM Brasil
    1h 57m
    0
    10:03
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:00
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £39
  • LAN Airlines
    1h 57m
    0
    13:48
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    15:45
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £39
  • LAN Perú
    1h 57m
    0
    15:35
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    17:32
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £40
  • Cheapest Buses Tuesday

  • Pullman Bus
    20h 0m
    0
    01:00
    Antofagasta
    Camus Coach Station
    21:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £24
  • Andimar
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Andimar
    Economy
    £25
  • FlixBus
    18h 50m
    0
    03:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:50
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    £25
  • Pullman San Andres
    18h 30m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    07:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £27
  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £29

    Cheapest Buses Wednesday

  • Pullman Bus
    20h 0m
    0
    01:00
    Antofagasta
    Camus Coach Station
    21:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £24
  • Andimar
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Andimar
    Economy
    £25
  • FlixBus
    18h 50m
    0
    03:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:50
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    £25
  • Cormar Bus
    18h 30m
    0
    01:00
    Antofagasta
    Camus Coach Station
    19:30
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £26
  • Pullman San Andres
    18h 30m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    07:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £27
  • Cheapest Flights Wednesday

  • JetSmart
    1h 57m
    0
    12:14
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    14:11
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £33
  • Sky Airline
    1h 53m
    0
    08:50
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:43
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £34
  • Sky Airline
    1h 53m
    0
    16:47
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    18:40
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £34
  • JetSmart
    1h 57m
    0
    08:52
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:49
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £34
  • LATAM Brasil
    1h 57m
    0
    08:57
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:54
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £47

    Cheapest Buses Thursday

  • Andimar
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Andimar
    Economy
    £24
  • Pullman Bus
    20h 0m
    0
    01:00
    Antofagasta
    Camus Coach Station
    21:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £24
  • FlixBus
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    £24
  • Pullman San Andres
    18h 30m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    07:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £27
  • Cormar Bus
    18h 25m
    0
    23:45
    Antofagasta
    Camus Coach Station
    18:10
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £28
  • Cheapest Flights Thursday

  • Sky Airline
    3h 7m
    0
    13:38
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    16:45
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £39

What are the fastest trips from Antofagasta to Santiago, RM?

You can get to Santiago, RM from Antofagasta in just 1h 53m with a Flight from Sky Airline. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.

Friday
from 1h 53m
Saturday
from 1h 57m
Sunday
from 18h 0m
Monday
from 1h 53m
Tuesday
from 1h 53m
Wednesday
from 1h 53m
Thursday
from 3h 7m

    Fastest Flights Friday

  • Sky Airline
    1h 53m
    0
    08:50
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:43
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £36
  • JetSmart
    10h 13m
    0
    21:06
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    07:19
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £101
  • LAN Airlines
    11h 30m
    0
    19:49
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    07:19
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £113
  • JetSmart
    21h 51m
    0
    21:06
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    18:57
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £95
  • LAN Airlines
    23h 8m
    0
    19:49
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    18:57
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £107
  • Fastest Buses Friday

  • Andimar
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Andimar
    Economy
    £28
  • Pluss Chile
    18h 15m
    0
    01:31
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:46
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £29
  • Pullman San Andres
    18h 30m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    07:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £27
  • FlixBus
    18h 50m
    0
    03:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:50
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    £28
  • Cormar Bus
    19h 0m
    0
    13:50
    Antofagasta
    Camus Coach Station
    08:50
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £29

    Fastest Flights Saturday

  • JetSmart
    1h 57m
    0
    20:53
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    22:50
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £151
  • LAN Airlines
    5h 53m
    0
    11:30
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    17:23
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £100
  • LATAM Brasil
    5h 53m
    0
    11:30
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    17:23
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £102
  • LAN Airlines
    7h 27m
    0
    11:30
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    18:57
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £93
  • LATAM Brasil
    7h 27m
    0
    11:30
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    18:57
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £94
  • Fastest Buses Saturday

  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £29
  • Andimar
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Andimar
    Economy
    £26
  • Pullman San Andres
    18h 30m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    07:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £28
  • Cormar Bus
    19h 0m
    0
    13:50
    Antofagasta
    Camus Coach Station
    08:50
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £29
  • Pullman Bus
    20h 0m
    0
    01:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £27

    Fastest Buses Sunday

  • Andimar
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Andimar
    Economy
    £28
  • Cormar Bus
    18h 25m
    0
    23:45
    Antofagasta
    Camus Coach Station
    18:10
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £28
  • Pullman San Andres
    18h 30m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    07:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £27
  • FlixBus
    18h 50m
    0
    03:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:50
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    £28
  • Pullman Bus
    19h 15m
    0
    11:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    06:45
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £27

    Fastest Flights Monday

  • Sky Airline
    1h 53m
    0
    07:50
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:43
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £18
  • Sky Airline
    1h 53m
    0
    09:56
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    11:49
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £18
  • JetSmart
    1h 57m
    0
    07:48
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    09:45
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £17
  • JetSmart
    1h 57m
    0
    12:31
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    14:28
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £17
  • LAN Airlines
    1h 57m
    0
    08:47
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:44
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £20
  • Fastest Buses Monday

  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £29
  • Andimar
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Andimar
    Economy
    £25
  • Cormar Bus
    18h 25m
    0
    23:45
    Antofagasta
    Camus Coach Station
    18:10
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £28
  • Pullman San Andres
    18h 30m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    07:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £27
  • Pullman Bus
    19h 15m
    0
    11:30
    Antofagasta
    Camus Coach Station
    06:45
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £24

    Fastest Flights Tuesday

  • Sky Airline
    1h 53m
    0
    08:40
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:33
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £32
  • JetSmart
    1h 57m
    0
    17:05
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    19:02
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £23
  • LATAM Brasil
    1h 57m
    0
    10:03
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    12:00
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £39
  • LAN Airlines
    1h 57m
    0
    13:48
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    15:45
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Airlines
    Economy
    from £39
  • LAN Perú
    1h 57m
    0
    15:35
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    17:32
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LAN Perú
    Economy
    from £40
  • Fastest Buses Tuesday

  • Pluss Chile
    17h 30m
    0
    00:05
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    17:35
    Santiago, RM
    Sur Bus Station
    0
    Pluss Chile
    Premium Economy
    £29
  • Andimar
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Andimar
    Economy
    £25
  • Pullman San Andres
    18h 30m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    07:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £27
  • FlixBus
    18h 50m
    0
    03:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:50
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    £25
  • Pullman Bus
    20h 0m
    0
    01:00
    Antofagasta
    Camus Coach Station
    21:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £24

    Fastest Flights Wednesday

  • Sky Airline
    1h 53m
    0
    08:50
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:43
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £34
  • Sky Airline
    1h 53m
    0
    16:47
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    18:40
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £34
  • JetSmart
    1h 57m
    0
    12:14
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    14:11
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £33
  • JetSmart
    1h 57m
    0
    08:52
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:49
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    JetSmart
    Economy
    from £34
  • LATAM Brasil
    1h 57m
    0
    08:57
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    10:54
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    LATAM Brasil
    Economy
    from £47
  • Fastest Buses Wednesday

  • Andimar
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Andimar
    Economy
    £25
  • Cormar Bus
    18h 30m
    0
    01:00
    Antofagasta
    Camus Coach Station
    19:30
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £26
  • Pullman San Andres
    18h 30m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    07:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £27
  • FlixBus
    18h 50m
    0
    03:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    21:50
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    £25
  • Pullman Bus
    20h 0m
    0
    01:00
    Antofagasta
    Camus Coach Station
    21:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £24

    Fastest Flights Thursday

  • Sky Airline
    3h 7m
    0
    13:38
    Andrés Sabella Gálvez, Antofagasta Airport
    Andrés Sabella Gálvez, Antofagasta Airport
    16:45
    Santiago de Chile Airport
    Santiago de Chile Airport
    0
    Sky Airline
    Economy
    from £39
  • Fastest Buses Thursday

  • Andimar
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    Andimar
    Economy
    £24
  • FlixBus
    18h 0m
    0
    01:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    19:35
    Santiago, RM
    Terminal San Borja
    0
    FlixBus
    Economy
    £24
  • Cormar Bus
    18h 25m
    0
    23:45
    Antofagasta
    Camus Coach Station
    18:10
    Santiago, RM
    Terminal San Borja
    0
    Cormar Bus
    Premium Economy
    £28
  • Pullman San Andres
    18h 30m
    0
    13:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    07:30
    Santiago, RM
    Terminal San Borja
    0
    Pullman San Andres
    Premium Economy
    £27
  • Pullman Bus
    20h 0m
    0
    01:00
    Antofagasta
    Camus Coach Station
    21:00
    Santiago, RM
    Terminal San Borja
    0
    Pullman Bus
    First Class
    £24
Here you will find all operators and timetables for a Bus from Antofagasta to Santiago, RM

What are the most popular stations in Antofagasta and Santiago, RM?

In Antofagasta, you will usually depart from Maipú, Camus Coach Station or Carlos Oviedo Cavada Bus Station, while in Santiago, RM you will be arriving at Sur Bus Station, Terminal San Borja or Terminal Alameda, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Santiago, RM from Antofagasta? With 8 connections between 10 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Antofagasta and Santiago, RM, you can pay as low as £17 with a Flight from JetSmart.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Sky Airline: you will get to Santiago, RM in just 1h 53m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Antofagasta and Santiago, RM are JetSmart, Pullman San Andres and Andimar, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Antofagasta and Santiago, RM is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from La Negra or to Lo Prado, and look at flights from Andrés Sabella Gálvez, Antofagasta Airport, and landing at Santiago de Chile Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Antofagasta to Santiago, RM?

The most popular companies between Antofagasta and Santiago, RM, are JetSmart, Pullman San Andres and Andimar. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: Pullman San Andres, Andimar, Cormar Bus and 3 more.

Airlines: JetSmart, Sky Airline, LAN Airlines and 2 more.

All you need to know when you travel from Antofagasta to Santiago, RM

Check all information on comfort and services on all modes of transports from Antofagasta to Santiago, RM. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Antofagasta to Santiago, RM

How can I reach Santiago, RM from Antofagasta?

Every day, there are on average 8 connections between Flight and Bus, with which you can get to Santiago, RM from Antofagasta.

How far is Santiago, RM from Antofagasta?

The distance between Antofagasta and Santiago, RM is 1,089.2 km.

What is the most ecofriendly mode of transport between Antofagasta and Santiago, RM?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 29 kgs of CO2, a train 38 kgs, a car 185 kgs, and a flight 268 kgs.

What is the cheapest mode of transport from Antofagasta to Santiago, RM?

You can get to Santiago, RM with just £17 by taking a Flight from JetSmart.

What is the fastest way to get from Antofagasta to Santiago, RM?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Santiago, RM in just 1h 53m with a Flight from Sky Airline.

More routes to Antofagasta and to Santiago, RM

Looking for more options? Here you can see the most popular routes to Antofagasta and to Santiago, RM. Simply click on a connection, and you’ll find all the details about the route!

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