Bus from La Serena to Santiago and return

Find cheap coach tickets for your bus journey from La Serena to Santiago and back

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You're searching for bus from La Serena to Santiago or vice versa? is currently the most inexpensive coach company with prices starting from £0.02. The fastest bus is provided by and only needs 6 hr 0 min for the distance between the two cities. The earliest bus of the day leaves at 00:25 - or go with the last one at 23:15. The choice is yours: Simply click "Find Now", see all available coaches and take your pick!

  Bus La Serena - Santiago    397 km
Ø Bus connections4 x
Savings-58%

The cheapest coach connections from La Serena to Santiago

%No particular date in mind? Here's an overview of the cheapest bus tickets for the next few days.
Departure / Arrival
Date best offer
Company
Best price
  • La Serena
    Santiago
      17:15
      23:30
    30 Nov
    Voyhoy
    from £5.76
  • La Serena
    Santiago
      17:15
      23:30
    15 Nov
    Voyhoy
    from £5.79
  • La Serena
    Santiago
      17:15
      23:30
    6 Dec
    Voyhoy
    from £5.79
  • La Serena
    Santiago
      17:15
      23:30
    22 Nov
    Voyhoy
    from £5.80
  • La Serena
    Santiago
      17:15
      23:30
    16 Nov
    Voyhoy
    from £5.82
  • La Serena
    Santiago
      17:15
      23:30
    13 Nov
    Voyhoy
    from £5.82
  • La Serena
    Santiago
      23:30
      06:01
    27 Nov
    +1
    Recorrido
    from £9.37
  • La Serena
    Santiago
      23:30
      06:01
    20 Nov
    +1
    Recorrido
    from £9.37
  • La Serena
    Santiago
      23:30
      06:01
    17 Nov
    +1
    Recorrido
    from £9.37
  • La Serena
    Santiago
      23:30
      06:01
    22 Nov
    +1
    Recorrido
    from £9.37
  • La Serena
    Santiago
      23:30
      06:01
    23 Nov
    +1
    Recorrido
    from £9.37
  • La Serena
    Santiago
      23:30
      06:01
    13 Nov
    +1
    Recorrido
    from £9.37
  • La Serena
    Santiago
      23:59
      06:59
    18 Nov
    +1
    Recorrido
    from £12.22
  • La Serena
    Santiago
      23:15
      06:45
    13 Nov
    +1
    Voyhoy
    from £13.57


  Bus Santiago - La Serena    397 km
Ø Bus connections4 x
Savings-57%

The cheapest coach connections from Santiago to La Serena

%No particular date in mind? Here's an overview of the cheapest bus tickets for the next few days.
Departure / Arrival
Date best offer
Company
Best price
  • Santiago
    La Serena
      16:55
      23:00
    16 Nov
    Voyhoy
    from £5.79
  • Santiago
    La Serena
      16:55
      23:00
    13 Dec
    Voyhoy
    from £5.93
  • Santiago
    La Serena
      22:30
      04:45
    13 Nov
    +1
    Voyhoy
    from £8.15
  • Santiago
    La Serena
      22:30
      04:45
    13 Nov
    +1
    Recorrido
    from £9.10
  • Santiago
    La Serena
      23:30
      05:45
    19 Nov
    +1
    Recorrido
    from £10.86
  • Santiago
    La Serena
      12:25
      18:40
    18 Nov
    Recorrido
    from £10.86
  • Santiago
    La Serena
      23:30
      05:45
    22 Nov
    +1
    Recorrido
    from £10.86
  • Santiago
    La Serena
      23:30
      05:45
    14 Nov
    +1
    Recorrido
    from £10.86
  • Santiago
    La Serena
      23:30
      05:45
    17 Nov
    +1
    Recorrido
    from £10.86
  • Santiago
    La Serena
      23:30
      05:45
    28 Nov
    +1
    Recorrido
    from £10.86
  • Santiago
    La Serena
      23:15
      06:35
    29 Nov
    +1
    Voyhoy
    from £13.57
  • Santiago
    La Serena
      23:15
      06:35
    28 Nov
    +1
    Voyhoy
    from £13.57
  • Santiago
    La Serena
      23:15
      06:35
    14 Nov
    +1
    Voyhoy
    from £13.57
  • Santiago
    La Serena
      23:15
      06:35
    20 Nov
    +1
    Voyhoy
    from £13.58


Current ticket prices

Our website will help you get from La Serena to Santiago without having to break the bank. We recommend checking prices for different days because different dates normally mean different prices. Taking a look at other travel options can be a good idea, too. Check for trains, carpooling offers and flight deals to find unexpected travel bargains.

Bus stops in La Serena and Santiago

  Stations
Av. El Santo 1475, 1700000 La Serena (Chile)
  Stations
Av Libertador Bernardo O'Higgins 3850, 8320000 Santiago (Chile)

Find out more details about the service on your bus from La Serena to Santiago and return

If you want to go away but don’t know how, we would highly recommend checking the bus timetables. Taking the bus is not only an environmentally friendly option, it’s also quite inexpensive and as comfortable and convenient as taking a train or plane. Over the past few years, coach operators have really stepped up their game by offering top-notch amenities ranging from USB ports over multimedia centres to wireless internet at no extra cost. On CheckMyBus you can easily find out which companies offer which services. Also make sure to check the individual luggage allowances: Most coach companies operating the route La Serena - Santiago allow you to take hand baggage and one normal size suitcase on board for free. Additional or oversize luggage can usually be added for some extra pounds. Do you have all the information you need for a successful trip from Santiago to La Serena? Take a look at the exact location of the bus stations in both cities, check departure times and find the perfect ride. One last piece of advice: Browse our website for the latest promo codes. After all, everybody likes a good bargain, right?


La Serena and Santiago: Useful Info

La Serena
154,521
Santiago
4.84 Million
Taxi
£0.78
£1.20
La Serena
Santiago
A taxi journey in La Serena is 35% cheaper than in Santiago.
Local buses
£0.66
£0.84
La Serena
Santiago
A bus fare in La Serena is 22% cheaper than in Santiago.
Beer
£1.20
£1.80
La Serena
Santiago
A pint of beer in La Serena is 34% cheaper than in Santiago.
Water
£1.15
£1.02
La Serena
Santiago
A bottle of water in La Serena is 12% more expensive than in Santiago.
Meal
£12.01
£6.92
La Serena
Santiago
A meal in La Serena is 43% more expensive than in Santiago.