Which bus from La Serena to Santiago, RM is the cheapest?

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Which bus from La Serena to Santiago, RM is the best?

Check the bus schedule for La Serena to Santiago, RM. Here is a selection of the cheapest coach trips for the next days from bus operators like Pluss Chile, Turbus or FlixBus. To see the full timetable for all coaches just use or search and compare.

today
£9
tomorrow
£9
Tuesday
£9
Wednesday
£9
Thursday
£9
Friday
£9
Saturday
£9

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Pluss Chile 6h 40m 10:21 La Serena Central Coach Station 17:01 Santiago, RM Sur Bus Station  Premium Economy £9
Turbus 6h 35m 16:35 La Serena Avda. Fco de Aguirre Station 23:10 Santiago, RM Terminal Alameda  Premium Economy £9
Cikbus Elité 7h 5m 09:55 La Serena Central Coach Station 17:00 Santiago, RM Sur Bus Station  Premium Economy £11
Cormar Bus 6h 30m 22:50 La Serena Central Coach Station 05:20 Santiago, RM Terminal San Borja  Premium Economy £12
Pullman Bus 7h 45m 22:15 La Serena El Sto, 1060 06:00 Santiago, RM Terminal San Borja  First Class £12

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Pluss Chile 6h 30m 00:05 La Serena Central Coach Station 06:35 Santiago, RM Sur Bus Station  Premium Economy £9
Turbus 6h 20m 04:45 La Serena Avda. Fco de Aguirre Station 11:05 Santiago, RM Terminal Alameda  Premium Economy £9
Condor Bus 6h 35m 04:15 La Serena Central Coach Station 10:50 Santiago, RM Sur Bus Station  Premium Economy £10
Cikbus Elité 7h 5m 09:55 La Serena Central Coach Station 17:00 Santiago, RM Sur Bus Station  Premium Economy £11
Cormar Bus 6h 30m 23:30 La Serena Central Coach Station 06:00 Santiago, RM Terminal San Borja  Premium Economy £11

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Pluss Chile 6h 40m 00:05 La Serena Central Coach Station 06:45 Santiago, RM Sur Bus Station  Premium Economy £9
Turbus 6h 5m 06:55 La Serena Avda. Fco de Aguirre Station 13:00 Santiago, RM Terminal Alameda  Premium Economy £9
Condor Bus 6h 35m 00:45 La Serena Central Coach Station 07:20 Santiago, RM Sur Bus Station  Premium Economy £10
Cikbus Elité 7h 5m 09:55 La Serena Central Coach Station 17:00 Santiago, RM Sur Bus Station  Premium Economy £11
Cormar Bus 6h 30m 23:30 La Serena Central Coach Station 06:00 Santiago, RM Terminal San Borja  Premium Economy £11

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Pluss Chile 6h 40m 00:05 La Serena Central Coach Station 06:45 Santiago, RM Sur Bus Station  Premium Economy £9
Turbus 6h 5m 06:55 La Serena Avda. Fco de Aguirre Station 13:00 Santiago, RM Terminal Alameda  Premium Economy £9
Condor Bus 6h 50m 03:15 La Serena Central Coach Station 10:05 Santiago, RM Sur Bus Station  Premium Economy £10
Pullman Bus 6h 0m 01:30 La Serena El Sto, 1060 07:30 Santiago, RM Terminal San Borja  Premium Economy £10
FlixBus 6h 30m 08:00 La Serena Central Coach Station 14:30 Santiago, RM Terminal San Borja  Economy £10

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Pluss Chile 6h 40m 00:05 La Serena Central Coach Station 06:45 Santiago, RM Sur Bus Station  Premium Economy £9
Turbus 6h 15m 02:30 La Serena Avda. Fco de Aguirre Station 08:45 Santiago, RM Terminal Alameda  Premium Economy £9
Cormar Bus 6h 30m 23:30 La Serena Central Coach Station 06:00 Santiago, RM Terminal San Borja  Premium Economy £10
Andimar 7h 15m 10:10 La Serena Central Coach Station 17:25 Santiago, RM Terminal San Borja  Economy £10
FlixBus 6h 30m 01:15 La Serena Central Coach Station 07:45 Santiago, RM Terminal San Borja  Economy £10

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Pluss Chile 6h 40m 00:05 La Serena Central Coach Station 06:45 Santiago, RM Sur Bus Station  Premium Economy £9
Turbus 6h 15m 05:35 La Serena Avda. Fco de Aguirre Station 11:50 Santiago, RM Terminal Alameda  Premium Economy £9
FlixBus 6h 5m 06:00 La Serena Central Coach Station 12:05 Santiago, RM Terminal San Borja  Economy £10
Andimar 5h 40m 13:55 La Serena Central Coach Station 19:35 Santiago, RM Terminal San Borja  Economy £10
Cikbus Elité 7h 5m 09:55 La Serena Central Coach Station 17:00 Santiago, RM Sur Bus Station  Premium Economy £11

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Pluss Chile 6h 30m 02:30 La Serena Central Coach Station 09:00 Santiago, RM Sur Bus Station  Premium Economy £9
Turbus 7h 15m 08:20 La Serena Avda. Fco de Aguirre Station 15:35 Santiago, RM Terminal Alameda  Premium Economy £9
Pullman Bus 6h 0m 01:30 La Serena El Sto, 1060 07:30 Santiago, RM Terminal San Borja  Premium Economy £10
FlixBus 6h 30m 08:00 La Serena Central Coach Station 14:30 Santiago, RM Terminal San Borja  Economy £10
Andimar 7h 15m 10:10 La Serena Central Coach Station 17:25 Santiago, RM Terminal San Borja  Economy £10

Best Price Offer: The price for the cheapest coach from La Serena to Santiago, RM is £8 on 27/10/2026. Flexible travellers save on ticket prices.


What is the best day and time to travel by bus between La Serena and Santiago, RM?

Here is the frequency of all coach connections from La Serena to Santiago, RM. See on which day of the week you have more travel options and what time you have more bus trips to choose from.
Wednesday is the busiest day, with more than 245 daily coaches from La Serena to Santiago, RM. Sunday has instead the fewest connections, with only 95 daily coaches between La Serena and Santiago, RM.
The busiest time of the day is the Night, with 422 coaches from La Serena to Santiago, RM, while Evening sees the fewest connections between La Serena and Santiago, RM, with 221 offers.

All facts for La Serena to Santiago, RM bus at a glance

Compare all coach operators like Pluss Chile, Turbus and FlixBus that travel daily 178 times by bus from La Serena to Santiago, RM in one click. Book your La Serena to Santiago, RM bus ticket starting from £8!

Cheapest Bus £8
Fastest Bus 5h 35m
Earliest Coach 08:10
Latest Coach 23:59
Daily Bus Connections 178 Ø
Distance 397.3 km
Coach Companies Pluss Chile, Turbus, FlixBus, Cikbus Elité, Pullman San Andres, Andimar, Buses Romani, Cormar Bus, Pullman Bus, Condor Bus and 2 more.

What are the cheapest coach tickets from La Serena to Santiago, RM?

Every day, 178 buses from 12 coach companies leave La Serena for Santiago, RM. Check the table below to find the cheapest prices for coach tickets for this route, starting from 01/11/2026 and for the following days. Make sure get the cheapest bus ticket!

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 26/10
Tuesday 27/10
Wednesday 28/10
Thursday 29/10
Friday 30/10
Saturday 31/10
Sunday 01/11
£12
Monday 02/11
£16
Tuesday 03/11
£9
Wednesday 04/11
£10
Thursday 05/11
£10
Friday 06/11
£9
Saturday 07/11
£9
Sunday 08/11
£10
Monday 09/11
£9
Tuesday 10/11
£9
Wednesday 11/11
£9
Thursday 12/11
£9
Friday 13/11
£10
Saturday 14/11
£9
Sunday 15/11
£9
Monday 16/11
£9
Tuesday 17/11
£9
Wednesday 18/11
£9
Thursday 19/11
£10
Friday 20/11
£10
Saturday 21/11
£9
Sunday 22/11

The cheapest time to travel from La Serena to Santiago, RM

See here on which day and which time of the day you can find the cheapest bus ticket from La Serena to Santiago, RM, for the next 30 days.
With a price starting from £9, Monday is the cheapest day for a coach from La Serena to Santiago, RM. Monday instead is the most expensive day with prices starting from £9.
Night is the cheapest day time for bus tickets from La Serena to Santiago, RM, with £9. Morning is the most expensive time of the day with prices starting from £9.

How to save money travelling from La Serena to Santiago, RM

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from La Serena to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from La Serena to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from La Serena to Santiago, RM are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

What are the most popular bus companies from La Serena to Santiago, RM?

These are the most booked bus companies by our users on the La Serena to Santiago, RM timetable.
In total 12 operators offer buses for this route. Find all bus timetables for them. Each coach company has a dedicated cancellation policy and possibilities for transport luggage on the bus. Check also special conditions to travel with kids or coach cards with rebates.

Latest reviews for coach companies on the route La Serena - Santiago, RM

Buses Romani
Paola Yáñez , 19/09/2026
Hola a todos los lectores. Mi experiencia fue muy buena en la línea de buses Romaní. Tomé el bus en el Terminal de la Serena un día miércoles a las 10:30 am con destino a Santiago. El bus llegó unos 2 ... Hola a todos los lectores. Mi experiencia fue muy buena en la línea de buses Romaní. Tomé el bus en el Terminal de la Serena un día miércoles a las 10:30 am con destino a Santiago. El bus llegó unos 25 minutos antes, estaba limpio e higienizado, sin olores. Me fui en el segundo piso, los asientos cómodos y con buen espacio. El conductor y ayudante muy amables. Yo nunca me duermo en los viajes en bus, me gusta ir mirando, solo dormí unos 20 minutos por tanto puedo decir que el conductor manejó muy bien y el asistente subió varias veces a revisar que estuviéramos con cinturón de seguridad puesto menos mal le dijo a un pasajero que iba adelante que se pusiera el cinturón y las zapatillas porque se las había quitado, eso lo encuentro de mala educación y falta de respeto viajar como si estuvieras en el living de tu casa en un transporte público. Le coloco una nota 7 a la línea de buses, lo volvería a elegir en un próximo viaje.
FlixBus
Risa Manabe , 17/04/2026
Por lo general viajamos con mi pareja de serena a Santiago y nos acomoda el terminal los libertadores En dos ocasiones hemos tenido problemas con el bus y al cambiarnos no nos dan ninguna solución p ... Por lo general viajamos con mi pareja de serena a Santiago y nos acomoda el terminal los libertadores En dos ocasiones hemos tenido problemas con el bus y al cambiarnos no nos dan ninguna solución para llegar al mismo terminal ya que por eso compramos hacia terminal los libertadores y me parece de muy mal gusto que nos coloquen en otro bus al terminal Borja ,el problema no es el bus ni que nos cambien de bus por emergencia ,el problema es que no se reubiquen a los pasajeros del bus al mismo destino que uno saca el pasaje En este caso el destino era los libertadores y a mí pareja le cambiaron el bus y lo dejaron el el terminal Borja ...es la segunda vez que ocurre
Pluss Chile
carolina saavedra, 14/04/2026

Pésimo servicio,.los auxiliares maleducados, sin aire, parecía un sauna, los auxiliares prepotentes, pésima atención

Cormar Bus
Ana Riveros, 17/12/2025
El bus salió 1 hora atrasado Debía llegara la 8.15 a Santiago Y llegara a las 10 y yo debía estar a las 9.30 por un tema médico. Esto significa que perdí mi hora y el viaje. Por culpa de su neglige ... El bus salió 1 hora atrasado Debía llegara la 8.15 a Santiago Y llegara a las 10 y yo debía estar a las 9.30 por un tema médico. Esto significa que perdí mi hora y el viaje. Por culpa de su negligencia. Estaba acostumbrada a la puntualidad que siempre entregaban.
Pluss Chile
Claudia , 23/10/2025

El bus venía de Calama y salió con una hora de retraso.

Pluss Chile
Luis ig, 05/10/2025
Viaje en salón cama de la serena a Santiago y el bus salió una hora más tarde adema la máquina estaba hedionda y el asiento de reclinaba solo y el posa piernas estaba vencido por lo que todo el viaje ... Viaje en salón cama de la serena a Santiago y el bus salió una hora más tarde adema la máquina estaba hedionda y el asiento de reclinaba solo y el posa piernas estaba vencido por lo que todo el viaje me estuvo golpeando las piernas, pésimo el viaje.
Pluss Chile
Esteban Guerrero, 29/01/2025

Compré un pasaje de 6 horas en salón premium adelante en el parabrisas no había nada de espacio. Ultima vez que viajo en plus chile

All bus stations and stops in La Serena and Santiago, RM

Here is a map with all coach stations in La Serena and Santiago, RM. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from La Serena to Santiago, RM? Compare all modes of transports from La Serena to Santiago, RM.

All you need to know when you travel by bus from La Serena to Santiago, RM

Check all information on comfort and services on the coaches from La Serena to Santiago, RM. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for La Serena to Santiago, RM bus

How much does a La Serena Santiago, RM coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the La Serena Santiago, RM bus trip is available from £8 and takes 6h 40m. Compare offers and save money!

How much could I save by comparing buses from La Serena to Santiago, RM?

This connection is offered by 12 companies with ticket prices ranging from £8 to £26. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Santiago, RM.

How many connections are available for the La Serena Santiago, RM route on average every day?

Each day, the bus route from La Serena to Santiago, RM is offered by roughly 178 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Santiago, RM from La Serena take?

The quickest coach from La Serena to Santiago, RM is provided by Turbus and takes 5h 35m. Coach tickets for this connection cost £23. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from La Serena to Santiago, RM?

The earliest bus to Santiago, RM departs from La Serena at 08:10. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from La Serena to Santiago, RM?

The latest bus to Santiago, RM departs from La Serena at 23:59. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the La Serena Santiago, RM route?

Passengers looking to travel from La Serena to Santiago, RM can travel with Pluss Chile, Turbus and FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between La Serena and Santiago, RM?

You can check all the direct connections between La Serena and Santiago, RM by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pluss Chile, Turbus and FlixBus.

What can I take with me on the bus to Santiago, RM from La Serena?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the La Serena Santiago, RM bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the La Serena Santiago, RM bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from La Serena to Santiago, RM on your planned travel date.

How does CheckMyBus find the best coach deals from La Serena to Santiago, RM?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 178 daily trips between La Serena and Santiago, RM. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from La Serena to Santiago, RM?

Prices and availability for 178 trips between La Serena and Santiago, RM change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route La Serena to Santiago, RM

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to La Serena and to Santiago, RM

Here’s an overview of the most popular bus routes to La Serena and to Santiago, RM. Simply click on the connection of your choice, and you’ll find all the details about your bus route!

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