Which bus from La Serena to Santiago, RM is the cheapest?

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Which bus from La Serena to Santiago, RM is the best?

Check the bus schedule for La Serena to Santiago, RM. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus, Pullman Bus or Cikbus Elité. To see the full timetable for all coaches just use or search and compare.

today
£10
tomorrow
£7
Sunday
£8
Monday
£7
Tuesday
£7
Wednesday
£7
Thursday
£7

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Cikbus Elité 7h 0m 09:30 La Serena Central Coach Station 16:30 Santiago, RM Terminal San Borja  Business £10
Serena Mar 6h 0m 10:00 La Serena Central Coach Station 16:00 Santiago, RM Terminal San Borja  First Class £10
FlixBus 6h 5m 06:00 La Serena Central Coach Station 12:05 Santiago, RM Terminal San Borja  Premium Economy £11
Pullman Bus 6h 30m 05:30 La Serena El Sto, 1060 12:00 Santiago, RM Terminal San Borja  First Class £12
Cormar Bus 6h 40m 00:15 La Serena Central Coach Station 06:55 Santiago, RM Terminal San Borja  Premium Economy £12
  • Did you know that if you travel from La Serena to Santiago, RM via Coquimbo, you can save more than £0? You will find the corresponding connections below.
    • Save more than 1%
      5h 30m
      La Serena
      11 km
      10:30
      Coquimbo
      Coach Station
      16:00
      Santiago, RM
      Terminal San Borja
      0 km
      First Class
      £10

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Buses Romani 6h 15m 00:45 La Serena Central Coach Station 07:00 Santiago, RM Sur Bus Station  Premium Economy £7
FlixBus 6h 5m 11:00 La Serena Central Coach Station 17:05 Santiago, RM Terminal San Borja  Economy £9
Cormar Bus 6h 10m 13:20 La Serena Central Coach Station 19:30 Santiago, RM Terminal San Borja  First Class £11
Condor Bus 6h 15m 16:50 La Serena Central Coach Station 23:05 Santiago, RM Sur Bus Station  Premium Economy £11
Turbus 6h 25m 12:00 La Serena Avda. Fco de Aguirre Station 18:25 Santiago, RM Terminal Alameda  Premium Economy £12

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Buses Romani 6h 0m 09:00 La Serena Central Coach Station 15:00 Santiago, RM Terminal San Borja  Business £8
FlixBus 6h 5m 15:30 La Serena Central Coach Station 21:35 Santiago, RM Terminal San Borja  Economy £9
Cikbus Elité 7h 0m 09:30 La Serena Central Coach Station 16:30 Santiago, RM Terminal San Borja  Business £10
Serena Mar 6h 0m 10:00 La Serena Central Coach Station 16:00 Santiago, RM Terminal San Borja  First Class £10
Condor Bus 6h 35m 01:45 La Serena Central Coach Station 08:20 Santiago, RM Sur Bus Station  Premium Economy £11

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Buses Romani 6h 15m 00:45 La Serena Central Coach Station 07:00 Santiago, RM Sur Bus Station  Premium Economy £7
Turbus 6h 15m 02:30 La Serena Avda. Fco de Aguirre Station 08:45 Santiago, RM Terminal Alameda  Premium Economy £8
Cikbus Elité 7h 0m 09:30 La Serena Central Coach Station 16:30 Santiago, RM Terminal San Borja  Business £10
Serena Mar 6h 0m 10:00 La Serena Central Coach Station 16:00 Santiago, RM Terminal San Borja  First Class £10
Cormar Bus 6h 10m 13:20 La Serena Central Coach Station 19:30 Santiago, RM Terminal San Borja  First Class £12

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Buses Romani 6h 0m 09:00 La Serena Central Coach Station 15:00 Santiago, RM Sur Bus Station  Premium Economy £7
Cormar Bus 6h 10m 23:50 La Serena Central Coach Station 06:00 Santiago, RM Terminal San Borja  Premium Economy £8
Turbus 6h 5m 06:55 La Serena Avda. Fco de Aguirre Station 13:00 Santiago, RM Terminal Alameda  Premium Economy £8
Cikbus Elité 7h 0m 09:30 La Serena Central Coach Station 16:30 Santiago, RM Terminal San Borja  Business £10
Condor Bus 6h 15m 16:50 La Serena Central Coach Station 23:05 Santiago, RM Sur Bus Station  Premium Economy £11

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Buses Romani 6h 15m 00:45 La Serena Central Coach Station 07:00 Santiago, RM Sur Bus Station  Premium Economy £7
Cikbus Elité 7h 0m 09:30 La Serena Central Coach Station 16:30 Santiago, RM Terminal San Borja  Business £7
Condor Bus 6h 50m 03:15 La Serena Central Coach Station 10:05 Santiago, RM Sur Bus Station  Premium Economy £8
Cormar Bus 6h 20m 11:50 La Serena Central Coach Station 18:10 Santiago, RM Terminal San Borja  Premium Economy £8
FlixBus 6h 5m 06:00 La Serena Central Coach Station 12:05 Santiago, RM Terminal San Borja  Economy £8

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Buses Romani 6h 15m 00:45 La Serena Central Coach Station 07:00 Santiago, RM Sur Bus Station  Premium Economy £7
Cikbus Elité 7h 0m 09:30 La Serena Central Coach Station 16:30 Santiago, RM Terminal San Borja  Business £7
Condor Bus 7h 10m 21:45 La Serena Central Coach Station 04:55 Santiago, RM Sur Bus Station  Premium Economy £8
Turbus 6h 40m 21:20 La Serena Avda. Fco de Aguirre Station 04:00 Santiago, RM Terminal Alameda  Premium Economy £8
Cormar Bus 6h 10m 23:50 La Serena Central Coach Station 06:00 Santiago, RM Terminal San Borja  Premium Economy £8

Best Price Offer: The price for the cheapest coach from La Serena to Santiago, RM is £6 on 25/12/2025. Flexible travellers save on ticket prices.


What is the best day and time to travel by bus between La Serena and Santiago, RM?

Here is the frequency of all coach connections from La Serena to Santiago, RM. See on which day of the week you have more travel options and what time you have more bus trips to choose from.
Wednesday is the busiest day, with more than 318 daily coaches from La Serena to Santiago, RM. Thursday has instead the fewest connections, with only 240 daily coaches between La Serena and Santiago, RM.
The busiest time of the day is the Night, with 619 coaches from La Serena to Santiago, RM, while Evening sees the fewest connections between La Serena and Santiago, RM, with 294 offers.

All facts for La Serena to Santiago, RM bus at a glance

Compare all coach operators like FlixBus, Pullman Bus and Cikbus Elité that travel daily 272 times by bus from La Serena to Santiago, RM in one click. Book your La Serena to Santiago, RM bus ticket starting from £6!

Cheapest Bus £6
Fastest Bus 5h 40m
Earliest Coach 00:05
Latest Coach 23:59
Daily Bus Connections 272 Ø
Distance 397.3 km
Coach Companies FlixBus, Pullman Bus, Cikbus Elité, Turbus, Pullman San Andres, Pluss Chile, Buses Romani, Condor Bus, Cormar Bus, Nueva Andimar Vip and 2 more.

What are the cheapest coach tickets from La Serena to Santiago, RM?

Every day, 272 buses from 12 coach companies leave La Serena for Santiago, RM. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 01/12
Tuesday 02/12
Wednesday 03/12
Thursday 04/12
Friday 05/12
£13
Saturday 06/12
£20
Sunday 07/12
£9
Monday 08/12
£12
Tuesday 09/12
£8
Wednesday 10/12
£7
Thursday 11/12
£8
Friday 12/12
£10
Saturday 13/12
£10
Sunday 14/12
£10
Monday 15/12
£7
Tuesday 16/12
£6
Wednesday 17/12
£6
Thursday 18/12
£6
Friday 19/12
£8
Saturday 20/12
£8
Sunday 21/12
£8
Monday 22/12
£8
Tuesday 23/12
£7
Wednesday 24/12
£6
Thursday 25/12
£6
Friday 26/12
£21
Saturday 27/12
£19
Sunday 28/12

The cheapest time to travel from La Serena to Santiago, RM

See here on which day and which time of the day you can find the cheapest bus ticket from La Serena to Santiago, RM, for the next 30 days.
With a price starting from £6, Thursday is the cheapest day for a coach from La Serena to Santiago, RM. Friday instead is the most expensive day with prices starting from £8.
Night is the cheapest day time for bus tickets from La Serena to Santiago, RM, with £6. Afternoon is the most expensive time of the day with prices starting from £8.

How to save money travelling from La Serena to Santiago, RM

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from La Serena to Santiago, RM in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from La Serena to Santiago, RM, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from La Serena to Santiago, RM are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

What are the most popular bus companies from La Serena to Santiago, RM?

These are the most booked bus companies by our users on the La Serena to Santiago, RM timetable.
In total 12 operators offer buses for this route. Find all bus timetables for them. Each coach company has a dedicated cancellation policy and possibilities for transport luggage on the bus. Check also special conditions to travel with kids or coach cards with rebates.

Latest reviews for coach companies on the route La Serena - Santiago, RM

Pluss Chile
Claudia , 23/10/2025

El bus venía de Calama y salió con una hora de retraso.

Pluss Chile
Luis ig, 05/10/2025
Viaje en salón cama de la serena a Santiago y el bus salió una hora más tarde adema la máquina estaba hedionda y el asiento de reclinaba solo y el posa piernas estaba vencido por lo que todo el viaje ... Viaje en salón cama de la serena a Santiago y el bus salió una hora más tarde adema la máquina estaba hedionda y el asiento de reclinaba solo y el posa piernas estaba vencido por lo que todo el viaje me estuvo golpeando las piernas, pésimo el viaje.
Pluss Chile
Esteban Guerrero, 29/01/2025

Compré un pasaje de 6 horas en salón premium adelante en el parabrisas no había nada de espacio. Ultima vez que viajo en plus chile

All bus stations and stops in La Serena and Santiago, RM

Here is a map with all coach stations in La Serena and Santiago, RM. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from La Serena to Santiago, RM? Compare all modes of transports from La Serena to Santiago, RM.

All you need to know when you travel by bus from La Serena to Santiago, RM

Check all information on comfort and services on the coaches from La Serena to Santiago, RM. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for La Serena to Santiago, RM bus

How much does a La Serena Santiago, RM coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the La Serena Santiago, RM bus trip is available from £6 and takes 7h 0m. Compare offers and save money!

How much could I save by comparing buses from La Serena to Santiago, RM?

This connection is offered by 12 companies with ticket prices ranging from £6 to £29. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Santiago, RM.

How many connections are available for the La Serena Santiago, RM route on average every day?

Each day, the bus route from La Serena to Santiago, RM is offered by roughly 272 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Santiago, RM from La Serena take?

The quickest coach from La Serena to Santiago, RM is provided by Cormar Bus and takes 5h 40m. Coach tickets for this connection cost £14. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from La Serena to Santiago, RM?

The earliest bus to Santiago, RM departs from La Serena at 00:05. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from La Serena to Santiago, RM?

The latest bus to Santiago, RM departs from La Serena at 23:59. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the La Serena Santiago, RM route?

Passengers looking to travel from La Serena to Santiago, RM can travel with FlixBus, Pullman Bus and Cikbus Elité. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between La Serena and Santiago, RM?

You can check all the direct connections between La Serena and Santiago, RM by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Pullman Bus and Cikbus Elité.

What can I take with me on the bus to Santiago, RM from La Serena?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the La Serena Santiago, RM bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the La Serena Santiago, RM bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from La Serena to Santiago, RM on your planned travel date.

Available seat classes which are offered on the bus route La Serena to Santiago, RM

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to La Serena and to Santiago, RM

Here’s an overview of the most popular bus routes to La Serena and to Santiago, RM. Simply click on the connection of your choice, and you’ll find all the details about your bus route!

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