Bus and Coach from Talca, ML to La Serena: Compare all prices

Compare all timetables for the bus from Talca, ML to La Serena

Here is a selection of the cheapest bus trips from the schedule from Talca, ML to La Serena from various bus operators like FlixBus or Turbus for the next days.

today

£18

tomorrow

Thursday

£19

Friday

Saturday

£17

Sunday

£23

Monday

£24

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	10h 45m	17:45	Talca, ML	Cruce Varoli	04:30	La Serena	Central Coach Station		Economy	£18	A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 03/02/2026 17:45:00 to Central Coach Station, La Serena (Chile) arriving at 04/02/2026 04:30:00. 50 Economy ticket for £18 per person are available. Travel duration is 10h 45m
	FlixBus	10h 45m	13:45	Talca, ML	Cruce Varoli	00:30	La Serena	Central Coach Station		Economy	£23	A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 03/02/2026 13:45:00 to Central Coach Station, La Serena (Chile) arriving at 04/02/2026 00:30:00. 50 Economy ticket for £23 per person are available. Travel duration is 10h 45m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	10h 45m	17:45	Talca, ML	Cruce Varoli	04:30	La Serena	Central Coach Station	Economy	£19	A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 05/02/2026 17:45:00 to Central Coach Station, La Serena (Chile) arriving at 06/02/2026 04:30:00. 50 Economy ticket for £19 per person are available. Travel duration is 10h 45m
FlixBus	12h 20m	06:45	Talca, ML	Cruce Varoli	19:05	La Serena	Central Coach Station	Economy	£23	A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 05/02/2026 06:45:00 to Central Coach Station, La Serena (Chile) arriving at 05/02/2026 19:05:00. 50 Economy ticket for £23 per person are available. Travel duration is 12h 20m
FlixBus	10h 45m	13:45	Talca, ML	Cruce Varoli	00:30	La Serena	Central Coach Station	Economy	£23	A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 05/02/2026 13:45:00 to Central Coach Station, La Serena (Chile) arriving at 06/02/2026 00:30:00. 50 Economy ticket for £23 per person are available. Travel duration is 10h 45m
Turbus	10h 0m	12:10	Talca, ML	Central Bus Station	22:10	La Serena	Avda. Fco de Aguirre Station	Premium Economy	£28	A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 05/02/2026 12:10:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 05/02/2026 22:10:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 10h 0m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	10h 35m	13:45	Talca, ML	Cruce Varoli	00:20	La Serena	Central Coach Station	Economy	£17	A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 07/02/2026 13:45:00 to Central Coach Station, La Serena (Chile) arriving at 08/02/2026 00:20:00. 50 Economy ticket for £17 per person are available. Travel duration is 10h 35m
FlixBus	12h 20m	06:45	Talca, ML	Cruce Varoli	19:05	La Serena	Central Coach Station	Economy	£23	A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 07/02/2026 06:45:00 to Central Coach Station, La Serena (Chile) arriving at 07/02/2026 19:05:00. 50 Economy ticket for £23 per person are available. Travel duration is 12h 20m
FlixBus	11h 0m	17:45	Talca, ML	Cruce Varoli	04:45	La Serena	Central Coach Station	Economy	£23	A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 07/02/2026 17:45:00 to Central Coach Station, La Serena (Chile) arriving at 08/02/2026 04:45:00. 50 Economy ticket for £23 per person are available. Travel duration is 11h 0m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	12h 20m	06:45	Talca, ML	Cruce Varoli	19:05	La Serena	Central Coach Station	Economy	£23	A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 08/02/2026 06:45:00 to Central Coach Station, La Serena (Chile) arriving at 08/02/2026 19:05:00. 50 Economy ticket for £23 per person are available. Travel duration is 12h 20m
FlixBus	11h 0m	17:45	Talca, ML	Cruce Varoli	04:45	La Serena	Central Coach Station	Economy	£23	A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 08/02/2026 17:45:00 to Central Coach Station, La Serena (Chile) arriving at 09/02/2026 04:45:00. 50 Economy ticket for £23 per person are available. Travel duration is 11h 0m
Turbus	10h 0m	12:10	Talca, ML	Central Bus Station	22:10	La Serena	Avda. Fco de Aguirre Station	Premium Economy	£35	A Bus from Turbus goes from Central Bus Station, Talca, ML (Chile) at 08/02/2026 12:10:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 08/02/2026 22:10:00. 50 Premium Economy ticket for £35 per person are available. Travel duration is 10h 0m

Did you know that if you travel from Talca, ML to La Serena via Coquimbo, you can save more than £2? You can find the corresponding connections below.
- FlixBus
  
  13h 5m
  
  0
  
  13:45
  
  Talca, ML
  Cruce Varoli
  
  23:55
  
  Coquimbo
  Coach Station
  
  0
  
  Economy
  
  £17
  
  A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 07/02/2026 13:45:00 to Coach Station, Coquimbo (Chile) arriving at 07/02/2026 23:55:00. 50 Economy ticket for £17 per person are available. Travel duration is 10h 10m
- kupos.cl
  
  0h 20m
  
  0
  
  02:30
  
  Coquimbo
  Coach Station
  
  02:50
  
  La Serena
  El Sto, 1060
  
  0
  
  First Class
  
  £5
  
  A Bus from kupos.cl goes from Coach Station, Coquimbo (Chile) at 08/02/2026 02:30:00 to El Sto, 1060, La Serena (Chile) arriving at 08/02/2026 02:50:00. 50 First Class ticket for £5 per person are available. Travel duration is 0h 20m
Travel time is 3h 5m longer, but you will save £2

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	10h 45m	13:45	Talca, ML	Cruce Varoli	00:30	La Serena	Central Coach Station		Economy	£24	A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 09/02/2026 13:45:00 to Central Coach Station, La Serena (Chile) arriving at 10/02/2026 00:30:00. 50 Economy ticket for £24 per person are available. Travel duration is 10h 45m
	FlixBus	11h 0m	17:45	Talca, ML	Cruce Varoli	04:45	La Serena	Central Coach Station		Economy	£24	A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 09/02/2026 17:45:00 to Central Coach Station, La Serena (Chile) arriving at 10/02/2026 04:45:00. 50 Economy ticket for £24 per person are available. Travel duration is 11h 0m

Did you know that if you travel from Talca, ML to La Serena via Coquimbo, you can save more than £3? You can find the corresponding connections below.
- FlixBus
  
  13h 5m
  
  0
  
  13:45
  
  Talca, ML
  Cruce Varoli
  
  23:55
  
  Coquimbo
  Coach Station
  
  0
  
  Economy
  
  £17
  
  A Bus from FlixBus goes from Cruce Varoli, Talca, ML (Chile) at 07/02/2026 13:45:00 to Coach Station, Coquimbo (Chile) arriving at 07/02/2026 23:55:00. 50 Economy ticket for £17 per person are available. Travel duration is 10h 10m
- kupos.cl
  
  0h 20m
  
  0
  
  02:30
  
  Coquimbo
  Coach Station
  
  02:50
  
  La Serena
  El Sto, 1060
  
  0
  
  First Class
  
  £5
  
  A Bus from kupos.cl goes from Coach Station, Coquimbo (Chile) at 08/02/2026 02:30:00 to El Sto, 1060, La Serena (Chile) arriving at 08/02/2026 02:50:00. 50 First Class ticket for £5 per person are available. Travel duration is 0h 20m
Travel time is 2h 20m longer, but you will save £3

Best Price Offer: The price for the cheapest coach from Talca, ML to La Serena is £17 on 14/02/2026. Flexible travellers save on ticket prices.

Frequency of bus connections between Talca, ML and La Serena

See here how frequent the connections between Talca, ML and La Serena are, during different times and days of the week.

Thursday is the busiest day, with more than 4 daily coaches from Talca, ML to La Serena. Monday has instead the fewest connections, with only 2 daily coaches between Talca, ML and La Serena.

The busiest time of the day is the Afternoon, with 11 coaches from Talca, ML to La Serena, while Morning sees the fewest connections between Talca, ML and La Serena, with 3 offers.

Facts about coaches from Talca, ML to La Serena

Compare all providers like FlixBus and Turbus that travel 2 times every day by bus from Talca, ML to La Serena in one click! Book your bus ticket from Talca, ML to La Serena starting from £17!

Cheapest Bus	£17
Fastest Bus	10h 0m
Earliest Coach	13:45
Latest Coach	17:45
Daily Bus Connections	2 Ø
Distance	615.0 km
Coach Companies	FlixBus and Turbus

Cheapest coach connections from Talca, ML to La Serena

Every day, 2 buses from 2 coach companies leave Talca, ML for La Serena: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/02/2026 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 02/02

Tuesday 03/02

£18

Wednesday 04/02

Thursday 05/02

£28

Friday 06/02

Saturday 07/02

£17

Sunday 08/02

£23

Monday 09/02

£23

Tuesday 10/02

Wednesday 11/02

£18

Thursday 12/02

Friday 13/02

£26

Saturday 14/02

£17

Sunday 15/02

Monday 16/02

£23

Tuesday 17/02

Wednesday 18/02

Thursday 19/02

Friday 20/02

Saturday 21/02

Sunday 22/02

Monday 23/02

Tuesday 24/02

Wednesday 25/02

Thursday 26/02

Friday 27/02

Saturday 28/02

Sunday 01/03

The cheapest time to travel from Talca, ML to La Serena

See here on which day and which time of the day you can find the cheapest bus ticket from Talca, ML to La Serena, for the next 30 days.

With a price starting from £17, Saturday is the cheapest day for a coach from Talca, ML to La Serena. Monday instead is the most expensive day with prices starting from £23.

Afternoon is the cheapest day time for bus tickets from Talca, ML to La Serena, with £17. Morning is the most expensive time of the day with prices starting from £23.

How to save money travelling from Talca, ML to La Serena

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Talca, ML to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Talca, ML to La Serena, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Talca, ML to La Serena are also emptier.

All bus stations and stops in Talca, ML and La Serena

The map below shows you where to find all the bus stations in Talca, ML and La Serena.

Central Bus Station

Dos Sur 1932

Cruce Varoli

Calle 1 Norte / 18 ote

Terminal

Cruce Ruta 5

Avda. Fco de Aguirre Station

Avenida Francisco de Aguirre 410

Central Coach Station

Avenida El Santo 1475

El Sto, 1060

terminal de buses covalle bus

Rotonda

Service and Comfort on the bus from Talca, ML to La Serena

Want to know which seat classes are available on the coaches from Talca, ML to La Serena? Or which bus companies serve the route Talca, ML to La Serena? Below you will find answers to your questions.

FAQs about the Talca, ML to La Serena bus

How much does a Talca, ML - La Serena coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Talca, ML - La Serena bus trip is available from £17 and takes 10h 35m. Compare offers and save money!

How much could I save by comparing buses from Talca, ML to La Serena?

The connection Talca, ML to La Serena is offered by 2 companies with ticket prices ranging from £17 to £35. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Talca, ML - La Serena route on average every day?

Each day, the bus route from Talca, ML to La Serena is offered by roughly 2 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to La Serena from Talca, ML take?

The quickest coach from Talca, ML to La Serena is provided by Turbus and takes 10h 0m. Coach tickets for this connection cost £28. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Talca, ML to La Serena?

The earliest bus to La Serena departs from Talca, ML at 13:45. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Talca, ML to La Serena?

The latest bus to La Serena departs from Talca, ML at 17:45. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Talca, ML - La Serena route?

Passengers looking to travel from Talca, ML to La Serena can travel with FlixBus and Turbus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Talca, ML and La Serena?

You can check all the direct connections between Talca, ML and La Serena by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Turbus.

What can I take with me on the bus to La Serena from Talca, ML?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Talca, ML La Serena bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Talca, ML La Serena bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Talca, ML to La Serena on your planned travel date.

How does CheckMyBus find the best bus deals from Talca, ML to La Serena?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Talca, ML and La Serena. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Talca, ML to La Serena?

Prices and availability for 2 trips between Talca, ML and La Serena change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Talca, ML to La Serena

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Talca, ML and to La Serena

Here’s an overview of the most popular bus routes to Talca, ML and to La Serena. Simply click on the connection of your choice, and you will find all the details about your bus route!