What is the best way to travel from Santiago, RM to La Serena?
Looking for a trip? Check and compare all the available Buses and Flights to La Serena from Santiago, RM. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 17 available companies to find your perfect trip!
What is the cheapest way to reach La Serena from Santiago, RM?
You can reach La Serena with just £7 by taking a Bus from Buses Romani, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus6h 10m006:15Santiago, RMTerminal San Borja12:25La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 13/12/2025 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 13/12/2025 12:25:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 10m
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Nueva Andimar Vip6h 0m011:00Santiago, RMTerminal San Borja17:00La SerenaCentral Coach Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 13/12/2025 11:00:00 to Central Coach Station, La Serena (Chile) arriving at 13/12/2025 17:00:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 0m
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Turbus5h 55m013:50Santiago, RMTerminal Alameda19:45La SerenaAvda. Fco de Aguirre Station0Premium EconomyA Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 13/12/2025 13:50:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 13/12/2025 19:45:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 5h 55m
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Condor Bus7h 5m014:30Santiago, RMSur Bus Station21:35La SerenaCentral Coach Station0Premium EconomyA Bus from Condor Bus goes from Sur Bus Station, Santiago, RM (Chile) at 13/12/2025 14:30:00 to Central Coach Station, La Serena (Chile) arriving at 13/12/2025 21:35:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 7h 5m
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Pullman Bus6h 20m011:00Santiago, RMTerminal San Borja17:20La SerenaEl Sto, 10600First ClassA Bus from Pullman Bus goes from Terminal San Borja, Santiago, RM (Chile) at 13/12/2025 11:00:00 to El Sto, 1060, La Serena (Chile) arriving at 13/12/2025 17:20:00. 50 First Class ticket for £12 per person are available. Travel duration is 6h 20m
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LAN Perú1h 10m007:45Santiago de Chile AirportSantiago de Chile Airport08:55La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 13/12/2025 07:45:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 13/12/2025 08:55:00. 50 Economy ticket for £50 per person are available. Travel duration is 1h 10m
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Sky Airline1h 11m009:35Santiago de Chile AirportSantiago de Chile Airport10:46La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 13/12/2025 09:35:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 13/12/2025 10:46:00. 50 Economy ticket for £57 per person are available. Travel duration is 1h 11m
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LAN Perú1h 8m014:30Santiago de Chile AirportSantiago de Chile Airport15:38La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 13/12/2025 14:30:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 13/12/2025 15:38:00. 50 Economy ticket for £134 per person are available. Travel duration is 1h 8m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Buses Romani6h 30m010:30Santiago, RMSur Bus Station17:00La SerenaCentral Coach Station0Premium EconomyA Bus from Buses Romani goes from Sur Bus Station, Santiago, RM (Chile) at 14/12/2025 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 14/12/2025 17:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 30m
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Cormar Bus6h 30m012:00Santiago, RMTerminal San Borja18:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 14/12/2025 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 14/12/2025 18:30:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 30m
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FlixBus6h 5m006:15Santiago, RMTerminal San Borja12:20La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 14/12/2025 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 14/12/2025 12:20:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 5m
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Turbus6h 20m006:10Santiago, RMTerminal Alameda12:30La SerenaAvda. Fco de Aguirre Station0Premium EconomyA Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 14/12/2025 06:10:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 14/12/2025 12:30:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 20m
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Nueva Andimar Vip6h 0m007:50Santiago, RMTerminal San Borja13:50La SerenaCentral Coach Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 14/12/2025 07:50:00 to Central Coach Station, La Serena (Chile) arriving at 14/12/2025 13:50:00. 50 Economy ticket for £12 per person are available. Travel duration is 6h 0m
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LAN Perú1h 10m007:45Santiago de Chile AirportSantiago de Chile Airport08:55La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 14/12/2025 07:45:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 14/12/2025 08:55:00. 50 Economy ticket for £28 per person are available. Travel duration is 1h 10m
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JetSmart1h 10m007:51Santiago de Chile AirportSantiago de Chile Airport09:01La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 14/12/2025 07:51:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 14/12/2025 09:01:00. 50 Economy ticket for £29 per person are available. Travel duration is 1h 10m
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Sky Airline1h 11m009:15Santiago de Chile AirportSantiago de Chile Airport10:26La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 14/12/2025 09:15:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 14/12/2025 10:26:00. 50 Economy ticket for £34 per person are available. Travel duration is 1h 11m
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Sky Airline1h 11m014:03Santiago de Chile AirportSantiago de Chile Airport15:14La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 14/12/2025 14:03:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 14/12/2025 15:14:00. 50 Economy ticket for £43 per person are available. Travel duration is 1h 11m
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LAN Perú1h 10m010:36Santiago de Chile AirportSantiago de Chile Airport11:46La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 14/12/2025 10:36:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 14/12/2025 11:46:00. 50 Economy ticket for £48 per person are available. Travel duration is 1h 10m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Buses Romani6h 30m010:30Santiago, RMTerminal San Borja17:00La SerenaCentral Coach Station0BusinessA Bus from Buses Romani goes from Terminal San Borja, Santiago, RM (Chile) at 15/12/2025 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 15/12/2025 17:00:00. 50 Business ticket for £7 per person are available. Travel duration is 6h 30m
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Cormar Bus6h 10m013:00Santiago, RMTerminal San Borja19:10La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 15/12/2025 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 15/12/2025 19:10:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 10m
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FlixBus6h 10m006:15Santiago, RMTerminal San Borja12:25La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 15/12/2025 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 15/12/2025 12:25:00. 50 Economy ticket for £10 per person are available. Travel duration is 6h 10m
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Pullman San Andres6h 15m015:30Santiago, RMTerminal San Borja21:45La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 15/12/2025 15:30:00 to Central Coach Station, La Serena (Chile) arriving at 15/12/2025 21:45:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 6h 15m
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Cikbus Elité7h 10m013:30Santiago, RMTerminal San Borja20:40La SerenaCentral Coach Station0BusinessA Bus from Cikbus Elité goes from Terminal San Borja, Santiago, RM (Chile) at 15/12/2025 13:30:00 to Central Coach Station, La Serena (Chile) arriving at 15/12/2025 20:40:00. 50 Business ticket for £12 per person are available. Travel duration is 7h 10m
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Sky Airline1h 11m017:45Santiago de Chile AirportSantiago de Chile Airport18:56La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 15/12/2025 17:45:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 15/12/2025 18:56:00. 50 Economy ticket for £26 per person are available. Travel duration is 1h 11m
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Sky Airline1h 11m013:00Santiago de Chile AirportSantiago de Chile Airport14:11La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 15/12/2025 13:00:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 15/12/2025 14:11:00. 50 Economy ticket for £30 per person are available. Travel duration is 1h 11m
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JetSmart1h 10m019:12Santiago de Chile AirportSantiago de Chile Airport20:22La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 15/12/2025 19:12:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 15/12/2025 20:22:00. 50 Economy ticket for £47 per person are available. Travel duration is 1h 10m
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LAN Airlines1h 10m011:35Santiago de Chile AirportSantiago de Chile Airport12:45La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 15/12/2025 11:35:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 15/12/2025 12:45:00. 50 Economy ticket for £59 per person are available. Travel duration is 1h 10m
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LAN Perú1h 8m016:24Santiago de Chile AirportSantiago de Chile Airport17:32La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 15/12/2025 16:24:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 15/12/2025 17:32:00. 50 Economy ticket for £65 per person are available. Travel duration is 1h 8m
Cheapest Buses Monday
Cheapest Flights Monday
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Buses Romani6h 30m010:30Santiago, RMSur Bus Station17:00La SerenaCentral Coach Station0Premium EconomyA Bus from Buses Romani goes from Sur Bus Station, Santiago, RM (Chile) at 16/12/2025 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 16/12/2025 17:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 30m
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FlixBus6h 10m006:15Santiago, RMTerminal San Borja12:25La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 16/12/2025 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 16/12/2025 12:25:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Cormar Bus6h 30m012:00Santiago, RMTerminal San Borja18:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 16/12/2025 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 16/12/2025 18:30:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 30m
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Turbus6h 25m007:20Santiago, RMTerminal Alameda13:45La SerenaAvda. Fco de Aguirre Station0Premium EconomyA Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 16/12/2025 07:20:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 16/12/2025 13:45:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 25m
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Nueva Andimar Vip6h 0m007:50Santiago, RMTerminal San Borja13:50La SerenaCentral Coach Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 16/12/2025 07:50:00 to Central Coach Station, La Serena (Chile) arriving at 16/12/2025 13:50:00. 50 Economy ticket for £13 per person are available. Travel duration is 6h 0m
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Sky Airline1h 11m017:40Santiago de Chile AirportSantiago de Chile Airport18:51La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 16/12/2025 17:40:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 16/12/2025 18:51:00. 50 Economy ticket for £29 per person are available. Travel duration is 1h 11m
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JetSmart1h 10m019:05Santiago de Chile AirportSantiago de Chile Airport20:15La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 16/12/2025 19:05:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 16/12/2025 20:15:00. 50 Economy ticket for £33 per person are available. Travel duration is 1h 10m
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LAN Perú1h 8m018:52Santiago de Chile AirportSantiago de Chile Airport20:00La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 16/12/2025 18:52:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 16/12/2025 20:00:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 8m
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JetSmart1h 10m008:00Santiago de Chile AirportSantiago de Chile Airport09:10La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 16/12/2025 08:00:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 16/12/2025 09:10:00. 50 Economy ticket for £60 per person are available. Travel duration is 1h 10m
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LAN Airlines1h 10m011:48Santiago de Chile AirportSantiago de Chile Airport12:58La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 16/12/2025 11:48:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 16/12/2025 12:58:00. 50 Economy ticket for £70 per person are available. Travel duration is 1h 10m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Buses Romani6h 30m010:30Santiago, RMTerminal San Borja17:00La SerenaCentral Coach Station0BusinessA Bus from Buses Romani goes from Terminal San Borja, Santiago, RM (Chile) at 17/12/2025 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 17/12/2025 17:00:00. 50 Business ticket for £8 per person are available. Travel duration is 6h 30m
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FlixBus6h 10m006:15Santiago, RMTerminal San Borja12:25La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 17/12/2025 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 17/12/2025 12:25:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Cormar Bus6h 10m013:00Santiago, RMTerminal San Borja19:10La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 17/12/2025 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 17/12/2025 19:10:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Turbus6h 20m006:10Santiago, RMTerminal Alameda12:30La SerenaAvda. Fco de Aguirre Station0Premium EconomyA Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 17/12/2025 06:10:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 17/12/2025 12:30:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 20m
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Nueva Andimar Vip6h 0m007:50Santiago, RMTerminal San Borja13:50La SerenaCentral Coach Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 17/12/2025 07:50:00 to Central Coach Station, La Serena (Chile) arriving at 17/12/2025 13:50:00. 50 Economy ticket for £13 per person are available. Travel duration is 6h 0m
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LAN Airlines1h 8m014:01Santiago de Chile AirportSantiago de Chile Airport15:09La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 17/12/2025 14:01:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 17/12/2025 15:09:00. 50 Economy ticket for £33 per person are available. Travel duration is 1h 8m
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Sky Airline1h 11m011:22Santiago de Chile AirportSantiago de Chile Airport12:33La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 17/12/2025 11:22:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 17/12/2025 12:33:00. 50 Economy ticket for £35 per person are available. Travel duration is 1h 11m
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Sky Airline1h 11m010:41Santiago de Chile AirportSantiago de Chile Airport11:52La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 17/12/2025 10:41:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 17/12/2025 11:52:00. 50 Economy ticket for £36 per person are available. Travel duration is 1h 11m
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LAN Airlines1h 8m015:03Santiago de Chile AirportSantiago de Chile Airport16:11La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 17/12/2025 15:03:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 17/12/2025 16:11:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 8m
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LAN Perú1h 10m007:45Santiago de Chile AirportSantiago de Chile Airport08:55La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 17/12/2025 07:45:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 17/12/2025 08:55:00. 50 Economy ticket for £47 per person are available. Travel duration is 1h 10m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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Turbus6h 20m006:10Santiago, RMTerminal Alameda12:30La SerenaAvda. Fco de Aguirre Station0Premium EconomyA Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 18/12/2025 06:10:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 18/12/2025 12:30:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 20m
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Buses Romani6h 30m010:30Santiago, RMTerminal San Borja17:00La SerenaCentral Coach Station0BusinessA Bus from Buses Romani goes from Terminal San Borja, Santiago, RM (Chile) at 18/12/2025 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 18/12/2025 17:00:00. 50 Business ticket for £8 per person are available. Travel duration is 6h 30m
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FlixBus6h 10m006:15Santiago, RMTerminal San Borja12:25La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 18/12/2025 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 18/12/2025 12:25:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Cormar Bus6h 10m013:00Santiago, RMTerminal San Borja19:10La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 18/12/2025 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 18/12/2025 19:10:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Nueva Andimar Vip6h 0m007:50Santiago, RMTerminal San Borja13:50La SerenaCentral Coach Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 18/12/2025 07:50:00 to Central Coach Station, La Serena (Chile) arriving at 18/12/2025 13:50:00. 50 Economy ticket for £13 per person are available. Travel duration is 6h 0m
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JetSmart1h 10m008:17Santiago de Chile AirportSantiago de Chile Airport09:27La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 18/12/2025 08:17:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 18/12/2025 09:27:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 10m
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LAN Perú1h 15m007:40Santiago de Chile AirportSantiago de Chile Airport08:55La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 18/12/2025 07:40:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 18/12/2025 08:55:00. 50 Economy ticket for £31 per person are available. Travel duration is 1h 15m
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Sky Airline1h 11m012:25Santiago de Chile AirportSantiago de Chile Airport13:36La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 18/12/2025 12:25:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 18/12/2025 13:36:00. 50 Economy ticket for £34 per person are available. Travel duration is 1h 11m
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LAN Perú1h 13m017:43Santiago de Chile AirportSantiago de Chile Airport18:56La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 18/12/2025 17:43:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 18/12/2025 18:56:00. 50 Economy ticket for £36 per person are available. Travel duration is 1h 13m
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LAN Airlines1h 10m013:42Santiago de Chile AirportSantiago de Chile Airport14:52La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 18/12/2025 13:42:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 18/12/2025 14:52:00. 50 Economy ticket for £36 per person are available. Travel duration is 1h 10m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Turbus6h 25m007:20Santiago, RMTerminal Alameda13:45La SerenaAvda. Fco de Aguirre Station0Premium EconomyA Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 19/12/2025 07:20:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 19/12/2025 13:45:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 25m
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Buses Romani6h 30m010:30Santiago, RMTerminal San Borja17:00La SerenaCentral Coach Station0BusinessA Bus from Buses Romani goes from Terminal San Borja, Santiago, RM (Chile) at 19/12/2025 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 19/12/2025 17:00:00. 50 Business ticket for £8 per person are available. Travel duration is 6h 30m
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Cormar Bus6h 30m012:00Santiago, RMTerminal San Borja18:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 19/12/2025 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 19/12/2025 18:30:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 30m
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FlixBus6h 10m006:15Santiago, RMTerminal San Borja12:25La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 19/12/2025 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 19/12/2025 12:25:00. 50 Economy ticket for £10 per person are available. Travel duration is 6h 10m
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Pullman San Andres6h 15m007:00Santiago, RMTerminal San Borja13:15La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 19/12/2025 07:00:00 to Central Coach Station, La Serena (Chile) arriving at 19/12/2025 13:15:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 15m
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Sky Airline1h 11m018:03Santiago de Chile AirportSantiago de Chile Airport19:14La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 19/12/2025 18:03:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 19/12/2025 19:14:00. 50 Economy ticket for £39 per person are available. Travel duration is 1h 11m
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LAN Airlines1h 13m020:27Santiago de Chile AirportSantiago de Chile Airport21:40La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 19/12/2025 20:27:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 19/12/2025 21:40:00. 50 Economy ticket for £43 per person are available. Travel duration is 1h 13m
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JetSmart1h 10m016:22Santiago de Chile AirportSantiago de Chile Airport17:32La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 19/12/2025 16:22:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 19/12/2025 17:32:00. 50 Economy ticket for £45 per person are available. Travel duration is 1h 10m
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LAN Perú1h 13m019:34Santiago de Chile AirportSantiago de Chile Airport20:47La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 19/12/2025 19:34:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 19/12/2025 20:47:00. 50 Economy ticket for £70 per person are available. Travel duration is 1h 13m
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LAN Perú1h 15m007:40Santiago de Chile AirportSantiago de Chile Airport08:55La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 19/12/2025 07:40:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 19/12/2025 08:55:00. 50 Economy ticket for £80 per person are available. Travel duration is 1h 15m
Cheapest Buses Friday
Cheapest Flights Friday
What are the fastest trips from Santiago, RM to La Serena?
You can get to La Serena from Santiago, RM in just 1h 8m with a Flight from LAN Perú. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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LAN Perú1h 8m014:30Santiago de Chile AirportSantiago de Chile Airport15:38La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 13/12/2025 14:30:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 13/12/2025 15:38:00. 50 Economy ticket for £134 per person are available. Travel duration is 1h 8m
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LAN Perú1h 10m007:45Santiago de Chile AirportSantiago de Chile Airport08:55La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 13/12/2025 07:45:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 13/12/2025 08:55:00. 50 Economy ticket for £50 per person are available. Travel duration is 1h 10m
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Sky Airline1h 11m009:35Santiago de Chile AirportSantiago de Chile Airport10:46La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 13/12/2025 09:35:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 13/12/2025 10:46:00. 50 Economy ticket for £57 per person are available. Travel duration is 1h 11m
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Turbus5h 55m013:50Santiago, RMTerminal Alameda19:45La SerenaAvda. Fco de Aguirre Station0Premium EconomyA Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 13/12/2025 13:50:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 13/12/2025 19:45:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 5h 55m
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Nueva Andimar Vip6h 0m011:00Santiago, RMTerminal San Borja17:00La SerenaCentral Coach Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 13/12/2025 11:00:00 to Central Coach Station, La Serena (Chile) arriving at 13/12/2025 17:00:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 0m
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FlixBus6h 10m006:15Santiago, RMTerminal San Borja12:25La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 13/12/2025 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 13/12/2025 12:25:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 10m
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Pullman Bus6h 20m011:00Santiago, RMTerminal San Borja17:20La SerenaEl Sto, 10600First ClassA Bus from Pullman Bus goes from Terminal San Borja, Santiago, RM (Chile) at 13/12/2025 11:00:00 to El Sto, 1060, La Serena (Chile) arriving at 13/12/2025 17:20:00. 50 First Class ticket for £12 per person are available. Travel duration is 6h 20m
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Condor Bus7h 5m014:30Santiago, RMSur Bus Station21:35La SerenaCentral Coach Station0Premium EconomyA Bus from Condor Bus goes from Sur Bus Station, Santiago, RM (Chile) at 13/12/2025 14:30:00 to Central Coach Station, La Serena (Chile) arriving at 13/12/2025 21:35:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 7h 5m
Fastest Flights Saturday
Fastest Buses Saturday
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LAN Perú1h 10m007:45Santiago de Chile AirportSantiago de Chile Airport08:55La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 14/12/2025 07:45:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 14/12/2025 08:55:00. 50 Economy ticket for £28 per person are available. Travel duration is 1h 10m
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JetSmart1h 10m007:51Santiago de Chile AirportSantiago de Chile Airport09:01La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 14/12/2025 07:51:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 14/12/2025 09:01:00. 50 Economy ticket for £29 per person are available. Travel duration is 1h 10m
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LAN Perú1h 10m010:36Santiago de Chile AirportSantiago de Chile Airport11:46La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 14/12/2025 10:36:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 14/12/2025 11:46:00. 50 Economy ticket for £48 per person are available. Travel duration is 1h 10m
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Sky Airline1h 11m009:15Santiago de Chile AirportSantiago de Chile Airport10:26La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 14/12/2025 09:15:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 14/12/2025 10:26:00. 50 Economy ticket for £34 per person are available. Travel duration is 1h 11m
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Sky Airline1h 11m014:03Santiago de Chile AirportSantiago de Chile Airport15:14La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 14/12/2025 14:03:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 14/12/2025 15:14:00. 50 Economy ticket for £43 per person are available. Travel duration is 1h 11m
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Nueva Andimar Vip6h 0m007:50Santiago, RMTerminal San Borja13:50La SerenaCentral Coach Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 14/12/2025 07:50:00 to Central Coach Station, La Serena (Chile) arriving at 14/12/2025 13:50:00. 50 Economy ticket for £12 per person are available. Travel duration is 6h 0m
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FlixBus6h 5m006:15Santiago, RMTerminal San Borja12:20La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 14/12/2025 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 14/12/2025 12:20:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 5m
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Turbus6h 20m006:10Santiago, RMTerminal Alameda12:30La SerenaAvda. Fco de Aguirre Station0Premium EconomyA Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 14/12/2025 06:10:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 14/12/2025 12:30:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 20m
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Buses Romani6h 30m010:30Santiago, RMSur Bus Station17:00La SerenaCentral Coach Station0Premium EconomyA Bus from Buses Romani goes from Sur Bus Station, Santiago, RM (Chile) at 14/12/2025 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 14/12/2025 17:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 30m
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Cormar Bus6h 30m012:00Santiago, RMTerminal San Borja18:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 14/12/2025 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 14/12/2025 18:30:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 30m
Fastest Flights Sunday
Fastest Buses Sunday
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LAN Perú1h 8m016:24Santiago de Chile AirportSantiago de Chile Airport17:32La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 15/12/2025 16:24:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 15/12/2025 17:32:00. 50 Economy ticket for £65 per person are available. Travel duration is 1h 8m
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JetSmart1h 10m019:12Santiago de Chile AirportSantiago de Chile Airport20:22La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 15/12/2025 19:12:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 15/12/2025 20:22:00. 50 Economy ticket for £47 per person are available. Travel duration is 1h 10m
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LAN Airlines1h 10m011:35Santiago de Chile AirportSantiago de Chile Airport12:45La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 15/12/2025 11:35:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 15/12/2025 12:45:00. 50 Economy ticket for £59 per person are available. Travel duration is 1h 10m
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Sky Airline1h 11m017:45Santiago de Chile AirportSantiago de Chile Airport18:56La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 15/12/2025 17:45:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 15/12/2025 18:56:00. 50 Economy ticket for £26 per person are available. Travel duration is 1h 11m
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Sky Airline1h 11m013:00Santiago de Chile AirportSantiago de Chile Airport14:11La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 15/12/2025 13:00:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 15/12/2025 14:11:00. 50 Economy ticket for £30 per person are available. Travel duration is 1h 11m
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Cormar Bus6h 10m013:00Santiago, RMTerminal San Borja19:10La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 15/12/2025 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 15/12/2025 19:10:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 10m
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FlixBus6h 10m006:15Santiago, RMTerminal San Borja12:25La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 15/12/2025 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 15/12/2025 12:25:00. 50 Economy ticket for £10 per person are available. Travel duration is 6h 10m
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Pullman San Andres6h 15m015:30Santiago, RMTerminal San Borja21:45La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 15/12/2025 15:30:00 to Central Coach Station, La Serena (Chile) arriving at 15/12/2025 21:45:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 6h 15m
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Buses Romani6h 30m010:30Santiago, RMTerminal San Borja17:00La SerenaCentral Coach Station0BusinessA Bus from Buses Romani goes from Terminal San Borja, Santiago, RM (Chile) at 15/12/2025 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 15/12/2025 17:00:00. 50 Business ticket for £7 per person are available. Travel duration is 6h 30m
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Cikbus Elité7h 10m013:30Santiago, RMTerminal San Borja20:40La SerenaCentral Coach Station0BusinessA Bus from Cikbus Elité goes from Terminal San Borja, Santiago, RM (Chile) at 15/12/2025 13:30:00 to Central Coach Station, La Serena (Chile) arriving at 15/12/2025 20:40:00. 50 Business ticket for £12 per person are available. Travel duration is 7h 10m
Fastest Flights Monday
Fastest Buses Monday
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LAN Perú1h 8m018:52Santiago de Chile AirportSantiago de Chile Airport20:00La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 16/12/2025 18:52:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 16/12/2025 20:00:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 8m
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JetSmart1h 10m019:05Santiago de Chile AirportSantiago de Chile Airport20:15La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 16/12/2025 19:05:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 16/12/2025 20:15:00. 50 Economy ticket for £33 per person are available. Travel duration is 1h 10m
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JetSmart1h 10m008:00Santiago de Chile AirportSantiago de Chile Airport09:10La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 16/12/2025 08:00:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 16/12/2025 09:10:00. 50 Economy ticket for £60 per person are available. Travel duration is 1h 10m
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LAN Airlines1h 10m011:48Santiago de Chile AirportSantiago de Chile Airport12:58La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 16/12/2025 11:48:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 16/12/2025 12:58:00. 50 Economy ticket for £70 per person are available. Travel duration is 1h 10m
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Sky Airline1h 11m017:40Santiago de Chile AirportSantiago de Chile Airport18:51La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 16/12/2025 17:40:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 16/12/2025 18:51:00. 50 Economy ticket for £29 per person are available. Travel duration is 1h 11m
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Nueva Andimar Vip6h 0m007:50Santiago, RMTerminal San Borja13:50La SerenaCentral Coach Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 16/12/2025 07:50:00 to Central Coach Station, La Serena (Chile) arriving at 16/12/2025 13:50:00. 50 Economy ticket for £13 per person are available. Travel duration is 6h 0m
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FlixBus6h 10m006:15Santiago, RMTerminal San Borja12:25La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 16/12/2025 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 16/12/2025 12:25:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Turbus6h 25m007:20Santiago, RMTerminal Alameda13:45La SerenaAvda. Fco de Aguirre Station0Premium EconomyA Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 16/12/2025 07:20:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 16/12/2025 13:45:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 25m
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Buses Romani6h 30m010:30Santiago, RMSur Bus Station17:00La SerenaCentral Coach Station0Premium EconomyA Bus from Buses Romani goes from Sur Bus Station, Santiago, RM (Chile) at 16/12/2025 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 16/12/2025 17:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 30m
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Cormar Bus6h 30m012:00Santiago, RMTerminal San Borja18:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 16/12/2025 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 16/12/2025 18:30:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 30m
Fastest Flights Tuesday
Fastest Buses Tuesday
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LAN Airlines1h 8m014:01Santiago de Chile AirportSantiago de Chile Airport15:09La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 17/12/2025 14:01:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 17/12/2025 15:09:00. 50 Economy ticket for £33 per person are available. Travel duration is 1h 8m
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LAN Airlines1h 8m015:03Santiago de Chile AirportSantiago de Chile Airport16:11La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 17/12/2025 15:03:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 17/12/2025 16:11:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 8m
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LAN Perú1h 10m007:45Santiago de Chile AirportSantiago de Chile Airport08:55La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 17/12/2025 07:45:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 17/12/2025 08:55:00. 50 Economy ticket for £47 per person are available. Travel duration is 1h 10m
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Sky Airline1h 11m011:22Santiago de Chile AirportSantiago de Chile Airport12:33La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 17/12/2025 11:22:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 17/12/2025 12:33:00. 50 Economy ticket for £35 per person are available. Travel duration is 1h 11m
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Sky Airline1h 11m010:41Santiago de Chile AirportSantiago de Chile Airport11:52La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 17/12/2025 10:41:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 17/12/2025 11:52:00. 50 Economy ticket for £36 per person are available. Travel duration is 1h 11m
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Nueva Andimar Vip6h 0m007:50Santiago, RMTerminal San Borja13:50La SerenaCentral Coach Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 17/12/2025 07:50:00 to Central Coach Station, La Serena (Chile) arriving at 17/12/2025 13:50:00. 50 Economy ticket for £13 per person are available. Travel duration is 6h 0m
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FlixBus6h 10m006:15Santiago, RMTerminal San Borja12:25La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 17/12/2025 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 17/12/2025 12:25:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Cormar Bus6h 10m013:00Santiago, RMTerminal San Borja19:10La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 17/12/2025 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 17/12/2025 19:10:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Turbus6h 20m006:10Santiago, RMTerminal Alameda12:30La SerenaAvda. Fco de Aguirre Station0Premium EconomyA Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 17/12/2025 06:10:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 17/12/2025 12:30:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 20m
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Buses Romani6h 30m010:30Santiago, RMTerminal San Borja17:00La SerenaCentral Coach Station0BusinessA Bus from Buses Romani goes from Terminal San Borja, Santiago, RM (Chile) at 17/12/2025 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 17/12/2025 17:00:00. 50 Business ticket for £8 per person are available. Travel duration is 6h 30m
Fastest Flights Wednesday
Fastest Buses Wednesday
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JetSmart1h 10m008:17Santiago de Chile AirportSantiago de Chile Airport09:27La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 18/12/2025 08:17:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 18/12/2025 09:27:00. 50 Economy ticket for £25 per person are available. Travel duration is 1h 10m
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LAN Airlines1h 10m013:42Santiago de Chile AirportSantiago de Chile Airport14:52La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 18/12/2025 13:42:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 18/12/2025 14:52:00. 50 Economy ticket for £36 per person are available. Travel duration is 1h 10m
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Sky Airline1h 11m012:25Santiago de Chile AirportSantiago de Chile Airport13:36La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 18/12/2025 12:25:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 18/12/2025 13:36:00. 50 Economy ticket for £34 per person are available. Travel duration is 1h 11m
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LAN Perú1h 13m017:43Santiago de Chile AirportSantiago de Chile Airport18:56La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 18/12/2025 17:43:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 18/12/2025 18:56:00. 50 Economy ticket for £36 per person are available. Travel duration is 1h 13m
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LAN Perú1h 15m007:40Santiago de Chile AirportSantiago de Chile Airport08:55La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 18/12/2025 07:40:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 18/12/2025 08:55:00. 50 Economy ticket for £31 per person are available. Travel duration is 1h 15m
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Nueva Andimar Vip6h 0m007:50Santiago, RMTerminal San Borja13:50La SerenaCentral Coach Station0EconomyA Bus from Nueva Andimar Vip goes from Terminal San Borja, Santiago, RM (Chile) at 18/12/2025 07:50:00 to Central Coach Station, La Serena (Chile) arriving at 18/12/2025 13:50:00. 50 Economy ticket for £13 per person are available. Travel duration is 6h 0m
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FlixBus6h 10m006:15Santiago, RMTerminal San Borja12:25La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 18/12/2025 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 18/12/2025 12:25:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Cormar Bus6h 10m013:00Santiago, RMTerminal San Borja19:10La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 18/12/2025 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 18/12/2025 19:10:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Turbus6h 20m006:10Santiago, RMTerminal Alameda12:30La SerenaAvda. Fco de Aguirre Station0Premium EconomyA Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 18/12/2025 06:10:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 18/12/2025 12:30:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 20m
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Buses Romani6h 30m010:30Santiago, RMTerminal San Borja17:00La SerenaCentral Coach Station0BusinessA Bus from Buses Romani goes from Terminal San Borja, Santiago, RM (Chile) at 18/12/2025 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 18/12/2025 17:00:00. 50 Business ticket for £8 per person are available. Travel duration is 6h 30m
Fastest Flights Thursday
Fastest Buses Thursday
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JetSmart1h 10m016:22Santiago de Chile AirportSantiago de Chile Airport17:32La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 19/12/2025 16:22:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 19/12/2025 17:32:00. 50 Economy ticket for £45 per person are available. Travel duration is 1h 10m
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Sky Airline1h 11m018:03Santiago de Chile AirportSantiago de Chile Airport19:14La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 19/12/2025 18:03:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 19/12/2025 19:14:00. 50 Economy ticket for £39 per person are available. Travel duration is 1h 11m
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LAN Airlines1h 13m020:27Santiago de Chile AirportSantiago de Chile Airport21:40La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 19/12/2025 20:27:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 19/12/2025 21:40:00. 50 Economy ticket for £43 per person are available. Travel duration is 1h 13m
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LAN Perú1h 13m019:34Santiago de Chile AirportSantiago de Chile Airport20:47La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 19/12/2025 19:34:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 19/12/2025 20:47:00. 50 Economy ticket for £70 per person are available. Travel duration is 1h 13m
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LAN Perú1h 15m007:40Santiago de Chile AirportSantiago de Chile Airport08:55La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Santiago de Chile Airport, Santiago de Chile Airport (Chile) at 19/12/2025 07:40:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 19/12/2025 08:55:00. 50 Economy ticket for £80 per person are available. Travel duration is 1h 15m
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FlixBus6h 10m006:15Santiago, RMTerminal San Borja12:25La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Terminal San Borja, Santiago, RM (Chile) at 19/12/2025 06:15:00 to Central Coach Station, La Serena (Chile) arriving at 19/12/2025 12:25:00. 50 Economy ticket for £10 per person are available. Travel duration is 6h 10m
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Pullman San Andres6h 15m007:00Santiago, RMTerminal San Borja13:15La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Terminal San Borja, Santiago, RM (Chile) at 19/12/2025 07:00:00 to Central Coach Station, La Serena (Chile) arriving at 19/12/2025 13:15:00. 50 Premium Economy ticket for £13 per person are available. Travel duration is 6h 15m
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Turbus6h 25m007:20Santiago, RMTerminal Alameda13:45La SerenaAvda. Fco de Aguirre Station0Premium EconomyA Bus from Turbus goes from Terminal Alameda, Santiago, RM (Chile) at 19/12/2025 07:20:00 to Avda. Fco de Aguirre Station, La Serena (Chile) arriving at 19/12/2025 13:45:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 25m
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Buses Romani6h 30m010:30Santiago, RMTerminal San Borja17:00La SerenaCentral Coach Station0BusinessA Bus from Buses Romani goes from Terminal San Borja, Santiago, RM (Chile) at 19/12/2025 10:30:00 to Central Coach Station, La Serena (Chile) arriving at 19/12/2025 17:00:00. 50 Business ticket for £8 per person are available. Travel duration is 6h 30m
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Cormar Bus6h 30m012:00Santiago, RMTerminal San Borja18:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Terminal San Borja, Santiago, RM (Chile) at 19/12/2025 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 19/12/2025 18:30:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 30m
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Here you will find all operators and timetables for a
Bus from Santiago, RM to La Serena
What are the most popular stations in Santiago, RM and La Serena?
In Santiago, RM, you will usually depart from Terminal Alameda, Terminal San Borja or Sur Bus Station, while in La Serena you will be arriving at Avda. Fco de Aguirre Station, Central Coach Station or El Sto, 1060, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to La Serena from Santiago, RM? With 9 connections between 17 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Santiago, RM and La Serena, you can pay as low as £7 with a Bus from Buses Romani.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from LAN Perú: you will get to La Serena in just 1h 8m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Santiago, RM and La Serena are LAN Perú, Sky Airline and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Santiago, RM and La Serena is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Lo Prado or to La Florida, La Serena Airport, and look at flights from Santiago de Chile Airport, and landing at La Florida, La Serena Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Santiago, RM to La Serena?
The most popular companies between Santiago, RM and La Serena, are LAN Perú, Sky Airline and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus, Turbus, Buses Romani and 6 more.
Airlines: LAN Perú, Sky Airline, JetSmart and 1 more.
All you need to know when you travel from Santiago, RM to La Serena
Check all information on comfort and services on all modes of transports from Santiago, RM to La Serena. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Santiago, RM to La Serena
How can I reach La Serena from Santiago, RM?
Every day, there are on average 9 connections between Bus and Flight, with which you can get to La Serena from Santiago, RM.
How far is La Serena from Santiago, RM?
The distance between Santiago, RM and La Serena is 397.3 km.
What is the most ecofriendly mode of transport between Santiago, RM and La Serena?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 11 kgs of CO2, a train 14 kgs, a car 68 kgs, and a flight 98 kgs.
What is the cheapest mode of transport from Santiago, RM to La Serena?
You can get to La Serena with just £7 by taking a Bus from Buses Romani.
What is the fastest way to get from Santiago, RM to La Serena?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to La Serena in just 1h 8m with a Flight from LAN Perú.
More routes to Santiago, RM and to La Serena
Looking for more options? Here you can see the most popular routes to Santiago, RM and to La Serena. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Santiago, RM
- Antofagasta to Santiago, RM
- Arica, AP to Santiago, RM
- Bariloche to Santiago, RM
- Buenos Aires to Santiago, RM
- Calama to Santiago, RM
- Concepción to Santiago, RM
- Copiapó to Santiago, RM
- Coquimbo to Santiago, RM
- Coronel to Santiago, RM
- Freire to Santiago, RM
- Iquique to Santiago, RM
- La Serena to Santiago, RM
- Mendoza to Santiago, RM
- Osorno, LL to Santiago, RM
- Puerto Montt to Santiago, RM
- Puerto Varas to Santiago, RM
- São Paulo to Santiago, RM
- Temuco to Santiago, RM
- Valdivia to Santiago, RM
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- Viña del Mar to Santiago, RM

