Bus tickets Santiago, RM to Antofagasta from £22

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Compare all timetables for the bus from Santiago, RM to Antofagasta

Here is a selection of the cheapest bus trips from the schedule from Santiago, RM to Antofagasta from various bus operators like Pullman San Andres, Pluss Chile or Pullman Bus for the next days.

today
£27
tomorrow
£29
Monday
£25
Tuesday
£22
Wednesday
£23
Thursday
£23
Friday
£24

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 17h 45m 07:50 Santiago, RM Terminal San Borja 01:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £27
Pullman San Andres 18h 40m 20:30 Santiago, RM Terminal San Borja 15:10 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Cikbus Elité 19h 0m 07:30 Santiago, RM Sur Bus Station 02:30 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Pullman Bus 18h 50m 11:00 Santiago, RM Terminal San Borja 05:50 Antofagasta Camus Coach Station  First Class £29
Pluss Chile 17h 55m 07:45 Santiago, RM Sur Bus Station 01:40 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Pullman San Andres 18h 40m 15:30 Santiago, RM Terminal San Borja 10:10 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Cikbus Elité 19h 0m 07:30 Santiago, RM Sur Bus Station 02:30 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Pluss Chile 17h 55m 07:45 Santiago, RM Sur Bus Station 01:40 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Nueva Andimar Vip 17h 45m 07:50 Santiago, RM Terminal San Borja 01:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £29
FlixBus 18h 35m 09:00 Santiago, RM Terminal San Borja 03:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £30
  • Did you know that if you travel from Santiago, RM to Antofagasta via La Serena, you can save more than £3? You can find the corresponding connections below.
    • Buses Romani
      17h 35m
      0
      10:30
      Santiago, RM
      Sur Bus Station
      17:00
      La Serena
      Central Coach Station
      0
      Buses Romani
      Premium Economy
      £7
      • Waiting Time 0h 20m
    • Pluss Chile
      10h 45m
      0
      17:20
      La Serena
      Central Coach Station
      04:05
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      Pluss Chile
      Premium Economy
      £19
    Travel Time is 0h 10m shorter, and you will save £3

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 35m 09:00 Santiago, RM Terminal San Borja 03:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £25
Nueva Andimar Vip 18h 35m 12:15 Santiago, RM Terminal San Borja 06:50 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £25
Pullman San Andres 18h 40m 15:30 Santiago, RM Terminal San Borja 10:10 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Cikbus Elité 19h 0m 07:30 Santiago, RM Sur Bus Station 02:30 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Ramos Cholele 17h 15m 11:45 Santiago, RM Terminal San Borja 05:00 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £33

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 17h 45m 07:50 Santiago, RM Terminal San Borja 01:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £22
Nueva Andimar Vip 18h 35m 12:15 Santiago, RM Terminal San Borja 06:50 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £22
Pullman San Andres 18h 40m 15:30 Santiago, RM Terminal San Borja 10:10 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Pluss Chile 17h 55m 07:45 Santiago, RM Sur Bus Station 01:40 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Cormar Bus 18h 20m 22:55 Santiago, RM Terminal San Borja 17:15 Antofagasta Camus Coach Station  Premium Economy £30

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 17h 45m 07:50 Santiago, RM Terminal San Borja 01:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £23
FlixBus 18h 35m 09:00 Santiago, RM Terminal San Borja 03:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £23
Pullman San Andres 18h 40m 15:30 Santiago, RM Terminal San Borja 10:10 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Cikbus Elité 19h 0m 07:30 Santiago, RM Sur Bus Station 02:30 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Pluss Chile 17h 55m 07:45 Santiago, RM Sur Bus Station 01:40 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Nueva Andimar Vip 17h 45m 07:50 Santiago, RM Terminal San Borja 01:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £23
Pullman San Andres 18h 40m 17:00 Santiago, RM Terminal San Borja 11:40 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Pluss Chile 17h 55m 07:45 Santiago, RM Sur Bus Station 01:40 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Pullman Bus 18h 50m 11:00 Santiago, RM Terminal San Borja 05:50 Antofagasta Camus Coach Station  First Class £29
FlixBus 18h 40m 10:05 Santiago, RM Los Libertadores Bus Stop 04:45 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £29
  • Did you know that if you travel from Santiago, RM to Antofagasta via La Serena, you can save more than £10? You can find the corresponding connections below.
    • Pluss Chile
      26h 20m
      0
      23:15
      Santiago, RM
      Sur Bus Station
      05:35
      La Serena
      Central Coach Station
      0
      Pluss Chile
      Premium Economy
      £8
      • Waiting Time 8h 25m
    • Nueva Andimar Vip
      11h 35m
      0
      14:00
      La Serena
      Central Coach Station
      01:35
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      Nueva Andimar Vip
      Economy
      £5
    Travel time is 8h 35m longer, but you will save £10

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 35m 09:00 Santiago, RM Terminal San Borja 03:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £24
Nueva Andimar Vip 17h 45m 07:50 Santiago, RM Terminal San Borja 01:35 Antofagasta Carlos Oviedo Cavada Bus Station  Economy £24
Cormar Bus 18h 40m 12:00 Santiago, RM Terminal San Borja 06:40 Antofagasta Camus Coach Station  Premium Economy £27
Pullman San Andres 18h 40m 15:30 Santiago, RM Terminal San Borja 10:10 Antofagasta Carlos Oviedo Cavada Bus Station  Premium Economy £29
Pullman Bus 18h 50m 11:00 Santiago, RM Terminal San Borja 05:50 Antofagasta Camus Coach Station  First Class £29
  • Did you know that if you travel from Santiago, RM to Antofagasta via La Serena, you can save more than £11? You can find the corresponding connections below.
    • Turbus
      18h 0m
      0
      13:50
      Santiago, RM
      Terminal Alameda
      20:00
      La Serena
      Avda. Fco de Aguirre Station
      0
      Turbus
      Premium Economy
      £8
      • Waiting Time 0h 15m
    • Nueva Andimar Vip
      11h 35m
      0
      20:15
      La Serena
      Central Coach Station
      07:50
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      Nueva Andimar Vip
      Economy
      £5
    Travel time is 0h 15m longer, but you will save £11

Best Price Offer: The price for the cheapest coach from Santiago, RM to Antofagasta is £22 on 07/04/2026. Flexible travellers save on ticket prices.


Frequency of bus connections between Santiago, RM and Antofagasta

See here how frequent the connections between Santiago, RM and Antofagasta are, during different times and days of the week.
Sunday is the busiest day, with more than 185 daily coaches from Santiago, RM to Antofagasta. Monday has instead the fewest connections, with only 76 daily coaches between Santiago, RM and Antofagasta.
The busiest time of the day is the Morning, with 304 coaches from Santiago, RM to Antofagasta, while Night sees the fewest connections between Santiago, RM and Antofagasta, with 2 offers.

Facts about coaches from Santiago, RM to Antofagasta

Compare all providers like Pullman San Andres, Pluss Chile and Pullman Bus that travel 119 times every day by bus from Santiago, RM to Antofagasta in one click! Book your bus ticket from Santiago, RM to Antofagasta starting from £22!

Cheapest Bus £22
Fastest Bus 16h 30m
Earliest Coach 00:00
Latest Coach 23:30
Daily Bus Connections 119 Ø
Distance 1,089.2 km
Coach Companies Pullman San Andres, Pluss Chile, Pullman Bus, Cikbus Elité, FlixBus, Cormar Bus, Nueva Andimar Vip, Gentour, Buses Norte Azul, Ramos Cholele and 2 more.

Cheapest coach connections from Santiago, RM to Antofagasta

Every day, 119 buses from 12 coach companies leave Santiago, RM for Antofagasta: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 21/03/2026 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 16/03
Tuesday 17/03
Wednesday 18/03
Thursday 19/03
Friday 20/03
Saturday 21/03
£26
Sunday 22/03
£31
Monday 23/03
£26
Tuesday 24/03
£22
Wednesday 25/03
£25
Thursday 26/03
£24
Friday 27/03
£24
Saturday 28/03
£24
Sunday 29/03
£23
Monday 30/03
£22
Tuesday 31/03
£29
Wednesday 01/04
£27
Thursday 02/04
£29
Friday 03/04
£28
Saturday 04/04
£29
Sunday 05/04
£28
Monday 06/04
£22
Tuesday 07/04
£22
Wednesday 08/04
£22
Thursday 09/04
£22
Friday 10/04
£22
Saturday 11/04
£22
Sunday 12/04

The cheapest time to travel from Santiago, RM to Antofagasta

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago, RM to Antofagasta, for the next 30 days.
With a price starting from £22, Tuesday is the cheapest day for a coach from Santiago, RM to Antofagasta. Monday instead is the most expensive day with prices starting from £22.
Night is the cheapest day time for bus tickets from Santiago, RM to Antofagasta, with £22. Evening is the most expensive time of the day with prices starting from £29.

How to save money travelling from Santiago, RM to Antofagasta

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago, RM to Antofagasta in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago, RM to Antofagasta, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Santiago, RM to Antofagasta are also emptier.

Beloved bus companies from Santiago, RM to Antofagasta

These are the most booked bus companies between Santiago, RM to Antofagasta from our users.

Pullman San Andres from Santiago, RM to Antofagasta

Pullman San Andres

Here you will find the key facts about the Pullman San Andres bus route Santiago, RM to Antofagasta:

Cheapest Price £29
Fastest Coach 17h 55m
Earliest Coach 08:00
Last Coach 23:30
Daily Connections 33 Ø
Found on 20/03/2026

Latest reviews for coach companies on the route Santiago, RM - Antofagasta

Gentour
German Burgos, 01/09/2025
Bus con muy mal olor, sube gente tomando y fuman en los baños asientos incómodos. Super malo el servicio dejan a las personas fuera de los terminales en la calle. El bus no entra a los terminales. Pa ... Bus con muy mal olor, sube gente tomando y fuman en los baños asientos incómodos. Super malo el servicio dejan a las personas fuera de los terminales en la calle. El bus no entra a los terminales. Para nunca más con Gentour.

All bus stations and stops in Santiago, RM and Antofagasta

The map below shows you where to find all the bus stations in Santiago, RM and Antofagasta.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Santiago, RM to Antofagasta? Compare all modes of transports from Santiago, RM to Antofagasta.

Service and Comfort on the bus from Santiago, RM to Antofagasta

Want to know which seat classes are available on the coaches from Santiago, RM to Antofagasta? Or which bus companies serve the route Santiago, RM to Antofagasta? Below you will find answers to your questions.

FAQs about the Santiago, RM to Antofagasta bus

How much does a Santiago, RM - Antofagasta coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Santiago, RM - Antofagasta bus trip is available from £22 and takes 17h 45m. Compare offers and save money!

How much could I save by comparing buses from Santiago, RM to Antofagasta?

The connection Santiago, RM to Antofagasta is offered by 12 companies with ticket prices ranging from £22 to £70. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Santiago, RM - Antofagasta route on average every day?

Each day, the bus route from Santiago, RM to Antofagasta is offered by roughly 119 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Antofagasta from Santiago, RM take?

The quickest coach from Santiago, RM to Antofagasta is provided by Gentour and takes 16h 30m. Coach tickets for this connection cost £37. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Santiago, RM to Antofagasta?

The earliest bus to Antofagasta departs from Santiago, RM at 00:00. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Santiago, RM to Antofagasta?

The latest bus to Antofagasta departs from Santiago, RM at 23:30. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Santiago, RM - Antofagasta route?

Passengers looking to travel from Santiago, RM to Antofagasta can travel with Pullman San Andres, Pluss Chile and Pullman Bus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Santiago, RM and Antofagasta?

You can check all the direct connections between Santiago, RM and Antofagasta by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pullman San Andres, Pluss Chile and Pullman Bus.

What can I take with me on the bus to Antofagasta from Santiago, RM?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Santiago, RM Antofagasta bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago, RM Antofagasta bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago, RM to Antofagasta on your planned travel date.

How does CheckMyBus find the best bus deals from Santiago, RM to Antofagasta?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 119 daily trips between Santiago, RM and Antofagasta. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Santiago, RM to Antofagasta?

Prices and availability for 119 trips between Santiago, RM and Antofagasta change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Santiago, RM to Antofagasta

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Santiago, RM and to Antofagasta

Here’s an overview of the most popular bus routes to Santiago, RM and to Antofagasta. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Temuco to Santiago, RM Bus Temuco to Santiago, RM
Coaches Pichilemu to Santiago, RM Coaches Pichilemu to Santiago, RM
Coach Lonquimay to Santiago, RM Coach Lonquimay to Santiago, RM
Buses Curacautin to Santiago, RM Buses Curacautin to Santiago, RM
Bus from Salta to Antofagasta Bus from Salta to Antofagasta
Coach from Arica, AP to Antofagasta Coach from Arica, AP to Antofagasta
Bus Calama to Antofagasta Bus Calama to Antofagasta
San Pedro de Atacama to Antofagasta coach San Pedro de Atacama to Antofagasta coach
Popular Airport Transfers to Santiago, RM and to Antofagasta
CheckMyBus › Coaches in Chile › Coach to Santiago, RM › Coach to Antofagasta

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