Bus tickets Santiago, RM to Antofagasta from £18

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Compare all timetables for the bus from Santiago, RM to Antofagasta

Here is a selection of the cheapest bus trips from the schedule from Santiago, RM to Antofagasta from various bus operators like Pullman Bus, Pullman San Andres or Cikbus Elité for the next days.

today
from £19
tomorrow
from £24
Monday
from £19
Tuesday
from £18
Wednesday
from £18
Thursday
from £18
Friday
from £22

Cheapest bus trips today

Prices are for one way and one person
  • Cikbus Elité
    19h 0m
    0
    08:00
    Santiago, RM
    Terminal San Borja
    03:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Business
    £19
  • Turbus
    18h 15m
    0
    07:20
    Santiago, RM
    Terminal Alameda
    01:35
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    £23
  • Pullman San Andres
    18h 0m
    0
    15:30
    Santiago, RM
    Terminal San Borja
    09:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    £27
  • Ramos Cholele
    16h 30m
    0
    09:30
    Santiago, RM
    Terminal San Borja
    02:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Ramos Cholele
    Premium Economy
    £27
  • Cormar Bus
    18h 10m
    0
    12:00
    Santiago, RM
    Terminal San Borja
    06:10
    Antofagasta
    Terminal Buses Camus
    0
    Cormar Bus
    First Class
    £29

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Cikbus Elité
    19h 0m
    0
    08:00
    Santiago, RM
    Sur Bus Station
    03:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    £24
  • Nueva Andimar Vip
    19h 0m
    0
    07:50
    Santiago, RM
    Sur Bus Station
    02:50
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    £25
  • Pullman San Andres
    18h 0m
    0
    15:30
    Santiago, RM
    Terminal San Borja
    09:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    £27
  • Ramos Cholele
    16h 30m
    0
    09:30
    Santiago, RM
    Terminal San Borja
    02:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Ramos Cholele
    Premium Economy
    £27
  • Pluss Chile
    17h 55m
    0
    07:45
    Santiago, RM
    Sur Bus Station
    01:40
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    £30
  • Did you know that if you travel from Santiago, RM to Antofagasta via Ovalle, you can save more than £6? You can find the corresponding connections below.
    • Recorrido CL
      18h 40m
      0
      09:30
      Santiago, RM
      Sur Bus Station
      14:45
      Ovalle
      Coach Station
      0
      Recorrido CL
      Premium Economy
      £6
      • Waiting Time 0h 15m
    • Recorrido CL
      13h 10m
      0
      15:00
      Ovalle
      Coach Station
      04:10
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      Recorrido CL
      Premium Economy
      £13
    Travel time is 2h 10m longer, but you will save £6

Cheapest bus trips Monday

Prices are for one way and one person
  • Cikbus Elité
    19h 5m
    0
    13:30
    Santiago, RM
    Terminal San Borja
    08:35
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Business
    £19
  • Turbus
    17h 25m
    0
    13:50
    Santiago, RM
    Terminal Alameda
    07:15
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    £23
  • Nueva Andimar Vip
    19h 0m
    0
    07:50
    Santiago, RM
    Sur Bus Station
    02:50
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    £23
  • Pullman San Andres
    18h 0m
    0
    15:30
    Santiago, RM
    Terminal San Borja
    09:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    £27
  • Ramos Cholele
    16h 30m
    0
    09:30
    Santiago, RM
    Terminal San Borja
    02:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Ramos Cholele
    Premium Economy
    £27

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Cikbus Elité
    18h 0m
    0
    23:00
    Santiago, RM
    Terminal San Borja
    17:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Business
    £18
  • Nueva Andimar Vip
    19h 0m
    0
    12:30
    Santiago, RM
    Sur Bus Station
    07:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    £23
  • Turbus
    18h 15m
    0
    07:20
    Santiago, RM
    Terminal Alameda
    01:35
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    £26
  • Pullman San Andres
    18h 0m
    0
    15:30
    Santiago, RM
    Terminal San Borja
    09:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    £27
  • Ramos Cholele
    16h 30m
    0
    09:30
    Santiago, RM
    Terminal San Borja
    02:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Ramos Cholele
    Premium Economy
    £27

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Cikbus Elité
    19h 0m
    0
    08:00
    Santiago, RM
    Terminal San Borja
    03:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Business
    £18
  • Turbus
    18h 35m
    0
    07:00
    Santiago, RM
    Terminal San Borja
    01:35
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    £23
  • Nueva Andimar Vip
    19h 0m
    0
    07:50
    Santiago, RM
    Sur Bus Station
    02:50
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    £23
  • Pullman San Andres
    18h 0m
    0
    15:30
    Santiago, RM
    Terminal San Borja
    09:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    £27
  • Pullman Bus
    18h 50m
    0
    10:00
    Santiago, RM
    Terminal San Borja
    04:50
    Antofagasta
    Terminal Buses Camus
    0
    Pullman Bus
    First Class
    £31

Cheapest bus trips Thursday

Prices are for one way and one person
  • Cikbus Elité
    19h 0m
    0
    08:00
    Santiago, RM
    Terminal San Borja
    03:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Business
    £18
  • Turbus
    18h 20m
    0
    12:30
    Santiago, RM
    Terminal Alameda
    06:50
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    £23
  • Pullman San Andres
    18h 0m
    0
    15:30
    Santiago, RM
    Terminal San Borja
    09:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    £27
  • Ramos Cholele
    16h 30m
    0
    09:30
    Santiago, RM
    Terminal San Borja
    02:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Ramos Cholele
    Premium Economy
    £27
  • Pluss Chile
    17h 55m
    0
    07:45
    Santiago, RM
    Sur Bus Station
    01:40
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pluss Chile
    Premium Economy
    £30

Cheapest bus trips Friday

Prices are for one way and one person
  • Cikbus Elité
    18h 15m
    0
    09:30
    Santiago, RM
    Sur Bus Station
    03:45
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Cikbus Elité
    Premium Economy
    £22
  • Turbus
    18h 15m
    0
    07:20
    Santiago, RM
    Terminal Alameda
    01:35
    Antofagasta
    Terminal Buses Camus
    0
    Turbus
    Premium Economy
    £23
  • Nueva Andimar Vip
    19h 0m
    0
    07:50
    Santiago, RM
    Sur Bus Station
    02:50
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Nueva Andimar Vip
    Premium Economy
    £23
  • Pullman San Andres
    18h 0m
    0
    15:30
    Santiago, RM
    Terminal San Borja
    09:30
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Pullman San Andres
    Premium Economy
    £27
  • Ramos Cholele
    16h 30m
    0
    09:30
    Santiago, RM
    Terminal San Borja
    02:00
    Antofagasta
    Carlos Oviedo Cavada Bus Station
    0
    Ramos Cholele
    Premium Economy
    £27
  • Did you know that if you travel from Santiago, RM to Antofagasta via Ovalle, you can save more than £4? You can find the corresponding connections below.
    • Recorrido CL
      18h 40m
      0
      09:30
      Santiago, RM
      Sur Bus Station
      14:45
      Ovalle
      Coach Station
      0
      Recorrido CL
      Premium Economy
      £6
      • Waiting Time 0h 15m
    • Recorrido CL
      13h 10m
      0
      15:00
      Ovalle
      Coach Station
      04:10
      Antofagasta
      Carlos Oviedo Cavada Bus Station
      0
      Recorrido CL
      Premium Economy
      £13
    Travel time is 2h 10m longer, but you will save £4

Frequency of bus connections between Santiago, RM and Antofagasta

See here how frequent the connections between Santiago, RM and Antofagasta are, during different times and days of the week.
Monday is the busiest day, with more than 140 daily coaches from Santiago, RM to Antofagasta. Friday has instead the fewest connections, with only 90 daily coaches between Santiago, RM and Antofagasta.
The busiest time of the day is the Morning, with 281 coaches from Santiago, RM to Antofagasta, while Night sees the fewest connections between Santiago, RM and Antofagasta, with 6 offers.

Facts about coaches from Santiago, RM to Antofagasta

Compare all providers like Pullman Bus, Pullman San Andres and Cikbus Elité that travel 109 times every day by bus from Santiago, RM to Antofagasta in one click! Book your bus ticket from Santiago, RM to Antofagasta starting from £18!

Cheapest Bus £18
Fastest Bus 16h 30m
Earliest Coach 01:30
Latest Coach 23:45
Daily Bus Connections 109 Ø
Distance 1,089.2 km
Coach Companies Pullman Bus, Pullman San Andres, Cikbus Elité, Pluss Chile, Turbus, Nueva Andimar Vip, Ramos Cholele and Cormar Bus

Cheapest coach connections from Santiago, RM to Antofagasta

Every day, 109 buses from 8 coach companies leave Santiago, RM for Antofagasta: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/07/2025 and for the following days.

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 07/07
Tuesday 08/07
Wednesday 09/07
Thursday 10/07
Friday 11/07
Saturday 12/07
£19
Sunday 13/07
£19
Monday 14/07
£23
Tuesday 15/07
£18
Wednesday 16/07
£23
Thursday 17/07
£30
Friday 18/07
£17
Saturday 19/07
£23
Sunday 20/07
£23
Monday 21/07
£23
Tuesday 22/07
£28
Wednesday 23/07
£30
Thursday 24/07
£20
Friday 25/07
£20
Saturday 26/07
£20
Sunday 27/07
£23
Monday 28/07
£20
Tuesday 29/07
£20
Wednesday 30/07
£20
Thursday 31/07
£20
Friday 01/08
£20
Saturday 02/08
£20
Sunday 03/08

The cheapest time to travel from Santiago, RM to Antofagasta

See here on which day and which time of the day you can find the cheapest bus ticket from Santiago, RM to Antofagasta, for the next 30 days.
With a price starting from £18, Tuesday is the cheapest day for a coach from Santiago, RM to Antofagasta. Sunday instead is the most expensive day with prices starting from £24.
Evening is the cheapest day time for bus tickets from Santiago, RM to Antofagasta, with £18. Night is the most expensive time of the day with prices starting from £48.

How to save money travelling from Santiago, RM to Antofagasta

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Santiago, RM to Antofagasta in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Santiago, RM to Antofagasta, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Santiago, RM to Antofagasta are also emptier.

Beloved bus companies from Santiago, RM to Antofagasta

These are the most booked bus companies between Santiago, RM to Antofagasta from our users.

Pluss Chile from Santiago, RM to Antofagasta

Pluss Chile

Here you will find the key facts about the Pluss Chile bus route Santiago, RM to Antofagasta:

Cheapest Price £16
Fastest Coach 17h 20m
Earliest Coach 07:45
Last Coach 23:15
Daily Connections 26 Ø
Found on 11/07/2025

All bus stations and stops in Santiago, RM and Antofagasta

The map below shows you where to find all the bus stations in Santiago, RM and Antofagasta.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Santiago, RM to Antofagasta? Compare all modes of transports from Santiago, RM to Antofagasta.

Service and Comfort on the bus from Santiago, RM to Antofagasta

Want to know which seat classes are available on the coaches from Santiago, RM to Antofagasta? Or which bus companies serve the route Santiago, RM to Antofagasta? Below you will find answers to your questions.

FAQs about the Santiago, RM to Antofagasta bus

How much does a Santiago, RM - Antofagasta coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Santiago, RM - Antofagasta bus trip is available from £18 and takes 18h 0m. Compare offers and save money!

How much could I save by comparing buses from Santiago, RM to Antofagasta?

The connection Santiago, RM to Antofagasta is offered by 8 companies with ticket prices ranging from £18 to £49. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Santiago, RM - Antofagasta route on average every day?

Each day, the bus route from Santiago, RM to Antofagasta is offered by roughly 109 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Antofagasta from Santiago, RM take?

The quickest coach from Santiago, RM to Antofagasta is provided by Ramos Cholele and takes 16h 30m. Coach tickets for this connection cost £30. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Santiago, RM to Antofagasta?

The earliest bus to Antofagasta departs from Santiago, RM at 01:30. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Santiago, RM to Antofagasta?

The latest bus to Antofagasta departs from Santiago, RM at 23:45. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Santiago, RM - Antofagasta route?

Passengers looking to travel from Santiago, RM to Antofagasta can travel with Pullman Bus, Pullman San Andres and Cikbus Elité. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Santiago, RM and Antofagasta?

You can check all the direct connections between Santiago, RM and Antofagasta by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Pullman Bus, Pullman San Andres and Cikbus Elité.

What can I take with me on the bus to Antofagasta from Santiago, RM?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Santiago, RM Antofagasta bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Santiago, RM Antofagasta bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Santiago, RM to Antofagasta on your planned travel date.

Available seat classes which are offered on the bus route Santiago, RM to Antofagasta

Premium Economy
PremiumEconomy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

Business
Business

Comfortable seating, food and drink service, accompanied generally by ticket flexibility.

First Class
First

Best of the best: you will find the most comfortable accommodation to work or relax during your travel.

More bus routes to Santiago, RM and to Antofagasta

Here’s an overview of the most popular bus routes to Santiago, RM and to Antofagasta. Simply click on the connection of your choice, and you will find all the details about your bus route!
Coaches Pitrufquén to Santiago, RM Coaches Pitrufquén to Santiago, RM
Quintero to Santiago, RM coach Quintero to Santiago, RM coach
Coach to Santiago, RM from Tongoy, CO Coach to Santiago, RM from Tongoy, CO
Rancagua to Santiago, RM bus Rancagua to Santiago, RM bus
Buses Iquique to Antofagasta Buses Iquique to Antofagasta
Coach from Arica, AP to Antofagasta Coach from Arica, AP to Antofagasta
Coach to Antofagasta from La Serena Coach to Antofagasta from La Serena
Bus Cochabamba to Antofagasta Bus Cochabamba to Antofagasta
Popular Airport Transfers to Santiago, RM and to Antofagasta
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