What is the best way to travel from Santander to Madrid?
Looking for a trip? Check and compare all the available Buses, Flights and Carpool to Madrid from Santander. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Madrid from Santander?
You can reach Madrid with just £19 by taking a Flight from Air Nostrum, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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ALSA6h 45m016:00SantanderCoach Station22:45MadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 22/03/2026 16:00:00 to Intercambiador de Moncloa, Madrid (Spain) arriving at 22/03/2026 22:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 6h 45m
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ALSA5h 30m017:30SantanderCoach Station23:00MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 22/03/2026 17:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 22/03/2026 23:00:00. 50 Economy ticket for £33 per person are available. Travel duration is 5h 30m
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ALSA5h 50m008:00SantanderCoach Station13:50MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 22/03/2026 08:00:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 22/03/2026 13:50:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 50m
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FlixBus18h 30m018:50SantanderCoach Station13:20MadridSur Bus Station0EconomyA Bus from FlixBus goes from Coach Station, Santander (Spain) at 22/03/2026 18:50:00 to Sur Bus Station, Madrid (Spain) arriving at 23/03/2026 13:20:00. 50 Economy ticket for £90 per person are available. Travel duration is 18h 30m
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Air Nostrum1h 10m017:40Santander AirportSantander Airport18:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 22/03/2026 17:40:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 22/03/2026 18:50:00. 50 Economy ticket for £286 per person are available. Travel duration is 1h 10m
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Iberia1h 10m009:25Santander AirportSantander Airport10:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 22/03/2026 09:25:00 to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 22/03/2026 10:35:00. 50 Economy ticket for £292 per person are available. Travel duration is 1h 10m
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Iberia1h 10m017:40Santander AirportSantander Airport18:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 22/03/2026 17:40:00 to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 22/03/2026 18:50:00. 50 Economy ticket for £292 per person are available. Travel duration is 1h 10m
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Vueling Airlines1h 10m009:25Santander AirportSantander Airport10:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Vueling Airlines goes from Santander Airport, Santander Airport (Spain) at 22/03/2026 09:25:00 to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 22/03/2026 10:35:00. 50 Economy ticket for £316 per person are available. Travel duration is 1h 10m
Cheapest Buses Sunday
Cheapest Flights Sunday
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ALSA5h 45m000:45SantanderCoach Station06:30MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 23/03/2026 00:45:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 23/03/2026 06:30:00. 50 Economy ticket for £30 per person are available. Travel duration is 5h 45m
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ALSA5h 15m015:30SantanderCoach Station20:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 23/03/2026 15:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 23/03/2026 20:45:00. 50 Economy ticket for £30 per person are available. Travel duration is 5h 15m
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ALSA6h 45m016:00SantanderCoach Station22:45MadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 23/03/2026 16:00:00 to Intercambiador de Moncloa, Madrid (Spain) arriving at 23/03/2026 22:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 6h 45m
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ALSA6h 15m010:30SantanderCoach Station16:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 23/03/2026 10:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 23/03/2026 16:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 6h 15m
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Air Nostrum1h 10m006:30Santander AirportSantander Airport07:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 23/03/2026 06:30:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 23/03/2026 07:40:00. 50 Economy ticket for £274 per person are available. Travel duration is 1h 10m
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Iberia1h 10m006:30Santander AirportSantander Airport07:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 23/03/2026 06:30:00 to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 23/03/2026 07:40:00. 50 Economy ticket for £287 per person are available. Travel duration is 1h 10m
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Iberia1h 10m009:00Santander AirportSantander Airport10:10Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 23/03/2026 09:00:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 23/03/2026 10:10:00. 50 Economy ticket for £291 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m017:40Santander AirportSantander Airport18:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 23/03/2026 17:40:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 23/03/2026 18:50:00. 50 Economy ticket for £291 per person are available. Travel duration is 1h 10m
Cheapest Buses Monday
Cheapest Flights Monday
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ALSA5h 45m000:45SantanderCoach Station06:30MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 24/03/2026 00:45:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 24/03/2026 06:30:00. 50 Economy ticket for £30 per person are available. Travel duration is 5h 45m
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ALSA6h 45m016:00SantanderCoach Station22:45MadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 24/03/2026 16:00:00 to Intercambiador de Moncloa, Madrid (Spain) arriving at 24/03/2026 22:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 6h 45m
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ALSA6h 15m010:30SantanderCoach Station16:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 24/03/2026 10:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 24/03/2026 16:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 6h 15m
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ALSA5h 45m012:00SantanderCoach Station17:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 24/03/2026 12:00:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 24/03/2026 17:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 5h 45m
Cheapest Buses Tuesday
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ALSA5h 45m000:45SantanderCoach Station06:30MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 25/03/2026 00:45:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 25/03/2026 06:30:00. 50 Economy ticket for £30 per person are available. Travel duration is 5h 45m
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ALSA6h 45m016:00SantanderCoach Station22:45MadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 25/03/2026 16:00:00 to Intercambiador de Moncloa, Madrid (Spain) arriving at 25/03/2026 22:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 6h 45m
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ALSA6h 15m010:30SantanderCoach Station16:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 25/03/2026 10:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 25/03/2026 16:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 6h 15m
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ALSA5h 45m012:00SantanderCoach Station17:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 25/03/2026 12:00:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 25/03/2026 17:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 5h 45m
Cheapest Buses Wednesday
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ALSA6h 45m016:00SantanderCoach Station22:45MadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 26/03/2026 16:00:00 to Intercambiador de Moncloa, Madrid (Spain) arriving at 26/03/2026 22:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 6h 45m
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ALSA6h 15m010:30SantanderCoach Station16:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 26/03/2026 10:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 26/03/2026 16:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 6h 15m
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ALSA5h 30m017:30SantanderCoach Station23:00MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 26/03/2026 17:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 26/03/2026 23:00:00. 50 Economy ticket for £32 per person are available. Travel duration is 5h 30m
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ALSA5h 45m000:45SantanderCoach Station06:30MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 26/03/2026 00:45:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 26/03/2026 06:30:00. 50 Economy ticket for £33 per person are available. Travel duration is 5h 45m
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Air Nostrum1h 10m017:40Santander AirportSantander Airport18:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 26/03/2026 17:40:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 26/03/2026 18:50:00. 50 Economy ticket for £90 per person are available. Travel duration is 1h 10m
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Iberia1h 10m009:00Santander AirportSantander Airport10:10Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 26/03/2026 09:00:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 26/03/2026 10:10:00. 50 Economy ticket for £114 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m006:30Santander AirportSantander Airport07:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 26/03/2026 06:30:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 26/03/2026 07:40:00. 50 Economy ticket for £127 per person are available. Travel duration is 1h 10m
Cheapest Buses Thursday
Cheapest Flights Thursday
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ALSA5h 45m000:45SantanderCoach Station06:30MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 27/03/2026 00:45:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 27/03/2026 06:30:00. 50 Economy ticket for £30 per person are available. Travel duration is 5h 45m
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ALSA6h 45m016:00SantanderCoach Station22:45MadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 27/03/2026 16:00:00 to Intercambiador de Moncloa, Madrid (Spain) arriving at 27/03/2026 22:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 6h 45m
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ALSA5h 30m017:30SantanderCoach Station23:00MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 27/03/2026 17:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 27/03/2026 23:00:00. 50 Economy ticket for £33 per person are available. Travel duration is 5h 30m
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FlixBus18h 30m018:50SantanderCoach Station13:20MadridSur Bus Station0EconomyA Bus from FlixBus goes from Coach Station, Santander (Spain) at 27/03/2026 18:50:00 to Sur Bus Station, Madrid (Spain) arriving at 28/03/2026 13:20:00. 50 Economy ticket for £73 per person are available. Travel duration is 18h 30m
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Iberia1h 10m006:30Santander AirportSantander Airport07:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 27/03/2026 06:30:00 to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 27/03/2026 07:40:00. 50 Economy ticket for £49 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m006:30Santander AirportSantander Airport07:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 27/03/2026 06:30:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 27/03/2026 07:40:00. 50 Economy ticket for £51 per person are available. Travel duration is 1h 10m
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Vueling Airlines1h 10m006:30Santander AirportSantander Airport07:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Vueling Airlines goes from Santander Airport, Santander Airport (Spain) at 27/03/2026 06:30:00 to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 27/03/2026 07:40:00. 50 Economy ticket for £52 per person are available. Travel duration is 1h 10m
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Iberia1h 10m009:00Santander AirportSantander Airport10:10Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 27/03/2026 09:00:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 27/03/2026 10:10:00. 50 Economy ticket for £66 per person are available. Travel duration is 1h 10m
Cheapest Buses Friday
Cheapest Flights Friday
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Air Nostrum1h 10m017:40Santander AirportSantander Airport18:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 28/03/2026 17:40:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 28/03/2026 18:50:00. 50 Economy ticket for £19 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m021:35Santander AirportSantander Airport22:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 28/03/2026 21:35:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 28/03/2026 22:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m009:25Santander AirportSantander Airport10:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 28/03/2026 09:25:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 28/03/2026 10:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 1h 10m
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ALSA6h 45m016:00SantanderCoach Station22:45MadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 28/03/2026 16:00:00 to Intercambiador de Moncloa, Madrid (Spain) arriving at 28/03/2026 22:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 6h 45m
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ALSA6h 15m010:30SantanderCoach Station16:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 28/03/2026 10:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 28/03/2026 16:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 6h 15m
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ALSA5h 45m012:00SantanderCoach Station17:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 28/03/2026 12:00:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 28/03/2026 17:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 5h 45m
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FlixBus18h 30m018:50SantanderCoach Station14:20MadridSur Bus Station0EconomyA Bus from FlixBus goes from Coach Station, Santander (Spain) at 28/03/2026 18:50:00 to Sur Bus Station, Madrid (Spain) arriving at 29/03/2026 14:20:00. 50 Economy ticket for £79 per person are available. Travel duration is 18h 30m
Cheapest Flights Saturday
Cheapest Buses Saturday
What are the fastest trips from Santander to Madrid?
You can get to Madrid from Santander in just 1h 10m with a Flight from Air Nostrum. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Air Nostrum1h 10m017:40Santander AirportSantander Airport18:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 22/03/2026 17:40:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 22/03/2026 18:50:00. 50 Economy ticket for £286 per person are available. Travel duration is 1h 10m
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Iberia1h 10m009:25Santander AirportSantander Airport10:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 22/03/2026 09:25:00 to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 22/03/2026 10:35:00. 50 Economy ticket for £292 per person are available. Travel duration is 1h 10m
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Iberia1h 10m017:40Santander AirportSantander Airport18:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 22/03/2026 17:40:00 to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 22/03/2026 18:50:00. 50 Economy ticket for £292 per person are available. Travel duration is 1h 10m
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Vueling Airlines1h 10m009:25Santander AirportSantander Airport10:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Vueling Airlines goes from Santander Airport, Santander Airport (Spain) at 22/03/2026 09:25:00 to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 22/03/2026 10:35:00. 50 Economy ticket for £316 per person are available. Travel duration is 1h 10m
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ALSA5h 30m017:30SantanderCoach Station23:00MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 22/03/2026 17:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 22/03/2026 23:00:00. 50 Economy ticket for £33 per person are available. Travel duration is 5h 30m
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ALSA5h 50m008:00SantanderCoach Station13:50MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 22/03/2026 08:00:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 22/03/2026 13:50:00. 50 Economy ticket for £35 per person are available. Travel duration is 5h 50m
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ALSA6h 45m016:00SantanderCoach Station22:45MadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 22/03/2026 16:00:00 to Intercambiador de Moncloa, Madrid (Spain) arriving at 22/03/2026 22:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 6h 45m
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FlixBus18h 30m018:50SantanderCoach Station13:20MadridSur Bus Station0EconomyA Bus from FlixBus goes from Coach Station, Santander (Spain) at 22/03/2026 18:50:00 to Sur Bus Station, Madrid (Spain) arriving at 23/03/2026 13:20:00. 50 Economy ticket for £90 per person are available. Travel duration is 18h 30m
Fastest Flights Sunday
Fastest Buses Sunday
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Air Nostrum1h 10m006:30Santander AirportSantander Airport07:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 23/03/2026 06:30:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 23/03/2026 07:40:00. 50 Economy ticket for £274 per person are available. Travel duration is 1h 10m
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Iberia1h 10m006:30Santander AirportSantander Airport07:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 23/03/2026 06:30:00 to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 23/03/2026 07:40:00. 50 Economy ticket for £287 per person are available. Travel duration is 1h 10m
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Iberia1h 10m009:00Santander AirportSantander Airport10:10Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 23/03/2026 09:00:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 23/03/2026 10:10:00. 50 Economy ticket for £291 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m017:40Santander AirportSantander Airport18:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 23/03/2026 17:40:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 23/03/2026 18:50:00. 50 Economy ticket for £291 per person are available. Travel duration is 1h 10m
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ALSA5h 15m015:30SantanderCoach Station20:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 23/03/2026 15:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 23/03/2026 20:45:00. 50 Economy ticket for £30 per person are available. Travel duration is 5h 15m
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ALSA5h 30m017:30SantanderCoach Station23:00MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 23/03/2026 17:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 23/03/2026 23:00:00. 50 Economy ticket for £33 per person are available. Travel duration is 5h 30m
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ALSA5h 45m000:45SantanderCoach Station06:30MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 23/03/2026 00:45:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 23/03/2026 06:30:00. 50 Economy ticket for £30 per person are available. Travel duration is 5h 45m
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ALSA6h 15m010:30SantanderCoach Station16:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 23/03/2026 10:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 23/03/2026 16:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 6h 15m
Fastest Flights Monday
Fastest Buses Monday
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ALSA5h 30m017:30SantanderCoach Station23:00MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 24/03/2026 17:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 24/03/2026 23:00:00. 50 Economy ticket for £33 per person are available. Travel duration is 5h 30m
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ALSA5h 45m000:45SantanderCoach Station06:30MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 24/03/2026 00:45:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 24/03/2026 06:30:00. 50 Economy ticket for £30 per person are available. Travel duration is 5h 45m
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ALSA5h 45m012:00SantanderCoach Station17:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 24/03/2026 12:00:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 24/03/2026 17:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 5h 45m
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ALSA6h 15m010:30SantanderCoach Station16:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 24/03/2026 10:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 24/03/2026 16:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 6h 15m
Fastest Buses Tuesday
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ALSA5h 45m000:45SantanderCoach Station06:30MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 25/03/2026 00:45:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 25/03/2026 06:30:00. 50 Economy ticket for £30 per person are available. Travel duration is 5h 45m
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ALSA5h 45m012:00SantanderCoach Station17:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 25/03/2026 12:00:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 25/03/2026 17:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 5h 45m
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ALSA5h 45m000:45SantanderCoach Station06:30MadridAvenida de Aragon0BasicA Bus from ALSA goes from Coach Station, Santander (Spain) at 25/03/2026 00:45:00 to Avenida de Aragon, Madrid (Spain) arriving at 25/03/2026 06:30:00. 50 Basic ticket for £33 per person are available. Travel duration is 5h 45m
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ALSA6h 15m010:30SantanderCoach Station16:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 25/03/2026 10:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 25/03/2026 16:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 6h 15m
Fastest Buses Wednesday
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Air Nostrum1h 10m017:40Santander AirportSantander Airport18:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 26/03/2026 17:40:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 26/03/2026 18:50:00. 50 Economy ticket for £90 per person are available. Travel duration is 1h 10m
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Iberia1h 10m009:00Santander AirportSantander Airport10:10Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 26/03/2026 09:00:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 26/03/2026 10:10:00. 50 Economy ticket for £114 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m006:30Santander AirportSantander Airport07:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 26/03/2026 06:30:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 26/03/2026 07:40:00. 50 Economy ticket for £127 per person are available. Travel duration is 1h 10m
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ALSA5h 30m017:30SantanderCoach Station23:00MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 26/03/2026 17:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 26/03/2026 23:00:00. 50 Economy ticket for £32 per person are available. Travel duration is 5h 30m
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ALSA5h 45m000:45SantanderCoach Station06:30MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 26/03/2026 00:45:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 26/03/2026 06:30:00. 50 Economy ticket for £33 per person are available. Travel duration is 5h 45m
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ALSA6h 15m010:30SantanderCoach Station16:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 26/03/2026 10:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 26/03/2026 16:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 6h 15m
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ALSA6h 15m010:30SantanderCoach Station16:45MadridAvenida de Aragon0BasicA Bus from ALSA goes from Coach Station, Santander (Spain) at 26/03/2026 10:30:00 to Avenida de Aragon, Madrid (Spain) arriving at 26/03/2026 16:45:00. 50 Basic ticket for £35 per person are available. Travel duration is 6h 15m
Fastest Flights Thursday
Fastest Buses Thursday
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Iberia1h 10m006:30Santander AirportSantander Airport07:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 27/03/2026 06:30:00 to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 27/03/2026 07:40:00. 50 Economy ticket for £49 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m006:30Santander AirportSantander Airport07:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 27/03/2026 06:30:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 27/03/2026 07:40:00. 50 Economy ticket for £51 per person are available. Travel duration is 1h 10m
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Vueling Airlines1h 10m006:30Santander AirportSantander Airport07:40Adolfo Suárez Madrid-Barajas AirportMadrid Airport0EconomyA Flight from Vueling Airlines goes from Santander Airport, Santander Airport (Spain) at 27/03/2026 06:30:00 to Madrid Airport, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 27/03/2026 07:40:00. 50 Economy ticket for £52 per person are available. Travel duration is 1h 10m
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Iberia1h 10m009:00Santander AirportSantander Airport10:10Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Iberia goes from Santander Airport, Santander Airport (Spain) at 27/03/2026 09:00:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 27/03/2026 10:10:00. 50 Economy ticket for £66 per person are available. Travel duration is 1h 10m
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ALSA5h 30m017:30SantanderCoach Station23:00MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 27/03/2026 17:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 27/03/2026 23:00:00. 50 Economy ticket for £33 per person are available. Travel duration is 5h 30m
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ALSA5h 45m000:45SantanderCoach Station06:30MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 27/03/2026 00:45:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 27/03/2026 06:30:00. 50 Economy ticket for £30 per person are available. Travel duration is 5h 45m
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ALSA6h 45m016:00SantanderCoach Station22:45MadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 27/03/2026 16:00:00 to Intercambiador de Moncloa, Madrid (Spain) arriving at 27/03/2026 22:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 6h 45m
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FlixBus18h 30m018:50SantanderCoach Station13:20MadridSur Bus Station0EconomyA Bus from FlixBus goes from Coach Station, Santander (Spain) at 27/03/2026 18:50:00 to Sur Bus Station, Madrid (Spain) arriving at 28/03/2026 13:20:00. 50 Economy ticket for £73 per person are available. Travel duration is 18h 30m
Fastest Flights Friday
Fastest Buses Friday
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Air Nostrum1h 10m017:40Santander AirportSantander Airport18:50Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 28/03/2026 17:40:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 28/03/2026 18:50:00. 50 Economy ticket for £19 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m021:35Santander AirportSantander Airport22:45Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 28/03/2026 21:35:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 28/03/2026 22:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 1h 10m
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Air Nostrum1h 10m009:25Santander AirportSantander Airport10:35Adolfo Suárez Madrid-Barajas AirportMadrid Airport - T40EconomyA Flight from Air Nostrum goes from Santander Airport, Santander Airport (Spain) at 28/03/2026 09:25:00 to Madrid Airport - T4, Adolfo Suárez Madrid-Barajas Airport (Spain) arriving at 28/03/2026 10:35:00. 50 Economy ticket for £52 per person are available. Travel duration is 1h 10m
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ALSA5h 45m012:00SantanderCoach Station17:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 28/03/2026 12:00:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 28/03/2026 17:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 5h 45m
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ALSA6h 15m010:30SantanderCoach Station16:45MadridAvenida de América Coach Station0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 28/03/2026 10:30:00 to Avenida de América Coach Station, Madrid (Spain) arriving at 28/03/2026 16:45:00. 50 Economy ticket for £32 per person are available. Travel duration is 6h 15m
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ALSA6h 45m016:00SantanderCoach Station22:45MadridIntercambiador de Moncloa0EconomyA Bus from ALSA goes from Coach Station, Santander (Spain) at 28/03/2026 16:00:00 to Intercambiador de Moncloa, Madrid (Spain) arriving at 28/03/2026 22:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 6h 45m
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FlixBus18h 30m018:50SantanderCoach Station14:20MadridSur Bus Station0EconomyA Bus from FlixBus goes from Coach Station, Santander (Spain) at 28/03/2026 18:50:00 to Sur Bus Station, Madrid (Spain) arriving at 29/03/2026 14:20:00. 50 Economy ticket for £79 per person are available. Travel duration is 18h 30m
Fastest Flights Saturday
Fastest Buses Saturday
Here you will find all operators and timetables for a
Bus from Santander to Madrid
What are the most popular stations in Santander and Madrid?
In Santander, you will usually depart from Coach Station, Astillero or Parayas Avenue Coach Stop, while in Madrid you will be arriving at Atocha Train Station, Chamartin Train Station or Sur Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Madrid from Santander? With 8 connections between 2 Carpool, Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Santander and Madrid, you can pay as low as £19 with a Flight from Air Nostrum.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Air Nostrum: you will get to Madrid in just 1h 10m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Santander and Madrid are ALSA, Air Nostrum and Iberia, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Santander and Madrid is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Santander Airport or to Delicias, and look at flights from Santander Airport, and landing at Adolfo Suárez Madrid-Barajas Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Santander to Madrid?
The most popular companies between Santander and Madrid, are ALSA, Air Nostrum and Iberia. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: ALSA and FlixBus
Airlines: Air Nostrum, Iberia and Vueling Airlines
All you need to know when you travel from Santander to Madrid
Check all information on comfort and services on all modes of transports from Santander to Madrid. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Santander to Madrid
How can I reach Madrid from Santander?
Every day, there are on average 8 connections between Carpool, Flight and Bus, with which you can get to Madrid from Santander.
How far is Madrid from Santander?
The distance between Santander and Madrid is 338.8 km.
What is the most ecofriendly mode of transport between Santander and Madrid?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 9 kgs of CO2, a train 12 kgs, a car 58 kgs, and a flight 83 kgs.
What is the cheapest mode of transport from Santander to Madrid?
You can get to Madrid with just £19 by taking a Flight from Air Nostrum.
What is the fastest way to get from Santander to Madrid?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Madrid in just 1h 10m with a Flight from Air Nostrum.
More routes to Santander and to Madrid
Looking for more options? Here you can see the most popular routes to Santander and to Madrid. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Santander
- A Coruña to Santander
- Adolfo Suárez Madrid-Barajas Airport to Santander
- Barcelona to Santander
- Bilbao to Santander
- Burgos to Santander
- León to Santander
- Logroño to Santander
- London to Santander
- Madrid to Santander
- Murcia to Santander
- Oviedo to Santander
- Pamplona to Santander
- Porto to Santander
- San Sebastian to Santander
- Santiago de Compostela to Santander
- Seville to Santander
- Valencia to Santander
- Valladolid to Santander
- Vitoria-Gasteiz to Santander
- Zaragoza to Santander
- Trips to Madrid
- Algeciras to Madrid
- Ávila to Madrid
- Barcelona to Madrid
- Bordeaux to Madrid
- Castellón de la Plana to Madrid
- Cordoba to Madrid
- Don Benito to Madrid
- Huelva to Madrid
- Lisbon to Madrid
- Logroño to Madrid
- Malaga to Madrid
- Murcia to Madrid
- Oviedo to Madrid
- Porto to Madrid
- San Rafael to Madrid
- San Sebastian to Madrid
- Segovia to Madrid
- Seville to Madrid
- Talavera de la Reina to Madrid
- Toledo (ES) to Madrid
- Toulouse to Madrid
- Trujillo to Madrid
- Valencia to Madrid
- Vigo to Madrid
