Bus and Coach from Rome to Brindisi: Compare all prices

Compare all timetables for the bus from Rome to Brindisi

Here is a selection of the cheapest bus trips from the schedule from Rome to Brindisi from various bus operators like Itabus, MarinoBus or FlixBus for the next days.

today

£30

tomorrow

£46

Saturday

£33

Sunday

£39

Monday

£48

Tuesday

£35

Wednesday

£19

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	8h 10m	08:25	Rome	Tiburtina Bus Station	16:35	Brindisi	Tribunale Bus Stop	Premium Economy	£30	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 18/12/2025 08:25:00 to Tribunale Bus Stop, Brindisi (Italy) arriving at 18/12/2025 16:35:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 8h 10m
Itabus	8h 10m	15:15	Rome	Tiburtina Bus Station	23:25	Brindisi	Tribunale Bus Stop	Premium Economy	£42	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 18/12/2025 15:15:00 to Tribunale Bus Stop, Brindisi (Italy) arriving at 18/12/2025 23:25:00. 50 Premium Economy ticket for £42 per person are available. Travel duration is 8h 10m
FlixBus	8h 25m	08:20	Rome	Tiburtina Bus Station	16:45	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£46	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 18/12/2025 08:20:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 18/12/2025 16:45:00. 50 Economy ticket for £46 per person are available. Travel duration is 8h 25m
FlixBus	8h 19m	09:30	Rome	Tiburtina Bus Station	17:49	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£50	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 18/12/2025 09:30:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 18/12/2025 17:49:00. 50 Economy ticket for £50 per person are available. Travel duration is 8h 19m
MarinoBus	7h 40m	07:00	Rome	Tiburtina Bus Station	14:40	Brindisi	Tribunale Bus Stop	Basic	£56	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 18/12/2025 07:00:00 to Tribunale Bus Stop, Brindisi (Italy) arriving at 18/12/2025 14:40:00. 50 Basic ticket for £56 per person are available. Travel duration is 7h 40m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	8h 19m	09:30	Rome	Tiburtina Bus Station	17:49	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£46	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 09:30:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 19/12/2025 17:49:00. 50 Economy ticket for £46 per person are available. Travel duration is 8h 19m
Itabus	8h 55m	23:35	Rome	Tiburtina Bus Station	08:30	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£48	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 23:35:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 20/12/2025 08:30:00. 50 Economy ticket for £48 per person are available. Travel duration is 8h 55m
Itabus	8h 10m	08:25	Rome	Tiburtina Bus Station	16:35	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Premium Economy	£55	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 08:25:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 19/12/2025 16:35:00. 50 Premium Economy ticket for £55 per person are available. Travel duration is 8h 10m
FlixBus	8h 25m	08:20	Rome	Tiburtina Bus Station	16:45	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£56	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 08:20:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 19/12/2025 16:45:00. 50 Economy ticket for £56 per person are available. Travel duration is 8h 25m
MarinoBus	7h 40m	07:00	Rome	Tiburtina Bus Station	14:40	Brindisi	Tribunale Bus Stop	Basic	£57	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 19/12/2025 07:00:00 to Tribunale Bus Stop, Brindisi (Italy) arriving at 19/12/2025 14:40:00. 50 Basic ticket for £57 per person are available. Travel duration is 7h 40m

Did you know that if you travel from Rome to Brindisi via Bari, you can save more than £7? You can find the corresponding connections below.
- INFOBUS
  
  7h 40m
  
  0
  
  12:00
  
  Rome
  Tiburtina Bus Station
  
  17:55
  
  Bari
  Central Bus Station
  
  0
  
  Economy
  
  £33
  
  A Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 20/12/2025 12:00:00 to Central Bus Station, Bari (Italy) arriving at 20/12/2025 17:55:00. 50 Economy ticket for £33 per person are available. Travel duration is 5h 55m
- Busbud
  
  1h 40m
  
  0
  
  18:00
  
  Bari
  Bari FS Park Coach Stop
  
  19:40
  
  Brindisi
  Via Giuseppe Maria Galanti Bus Stop
  
  0
  
  Premium Economy
  
  £6
  
  A Bus from Busbud goes from Bari FS Park Coach Stop, Bari (Italy) at 20/12/2025 18:00:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 20/12/2025 19:40:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 1h 40m
Travel time is the same as the direct connection, but you will save £7

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	8h 55m	23:35	Rome	Tiburtina Coach Station	08:30	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Basic	£33	A Bus from Itabus goes from Tiburtina Coach Station, Rome (Italy) at 20/12/2025 23:35:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 21/12/2025 08:30:00. 50 Basic ticket for £33 per person are available. Travel duration is 8h 55m
Itabus	7h 50m	23:40	Rome	Tiburtina Bus Station	07:30	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Premium Economy	£43	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 20/12/2025 23:40:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 21/12/2025 07:30:00. 50 Premium Economy ticket for £43 per person are available. Travel duration is 7h 50m
FlixBus	7h 40m	22:30	Rome	Tiburtina Bus Station	06:10	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£50	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 20/12/2025 22:30:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 21/12/2025 06:10:00. 50 Economy ticket for £50 per person are available. Travel duration is 7h 40m
FlixBus	7h 30m	23:45	Rome	Tiburtina Bus Station	07:15	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£56	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 20/12/2025 23:45:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 21/12/2025 07:15:00. 50 Economy ticket for £56 per person are available. Travel duration is 7h 30m
MarinoBus	8h 35m	23:50	Rome	Tiburtina Bus Station	08:25	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£57	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 20/12/2025 23:50:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 21/12/2025 08:25:00. 50 Economy ticket for £57 per person are available. Travel duration is 8h 35m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	8h 10m	15:15	Rome	Tiburtina Coach Station	23:25	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Basic	£39	A Bus from Itabus goes from Tiburtina Coach Station, Rome (Italy) at 21/12/2025 15:15:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 21/12/2025 23:25:00. 50 Basic ticket for £39 per person are available. Travel duration is 8h 10m
Itabus	7h 50m	23:40	Rome	Tiburtina Bus Station	07:30	Brindisi	Tribunale Bus Stop	Premium Economy	£42	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 21/12/2025 23:40:00 to Tribunale Bus Stop, Brindisi (Italy) arriving at 22/12/2025 07:30:00. 50 Premium Economy ticket for £42 per person are available. Travel duration is 7h 50m
MarinoBus	8h 35m	23:50	Rome	Tiburtina Bus Station	08:25	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£52	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 21/12/2025 23:50:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 22/12/2025 08:25:00. 50 Economy ticket for £52 per person are available. Travel duration is 8h 35m
MarinoBus	7h 40m	07:00	Rome	Tiburtina Bus Station	14:40	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£53	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 21/12/2025 07:00:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 21/12/2025 14:40:00. 50 Economy ticket for £53 per person are available. Travel duration is 7h 40m
FlixBus	7h 30m	23:45	Rome	Tiburtina Bus Station	07:15	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£56	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 21/12/2025 23:45:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 22/12/2025 07:15:00. 50 Economy ticket for £56 per person are available. Travel duration is 7h 30m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	8h 10m	15:15	Rome	Tiburtina Bus Station	23:25	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£48	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 22/12/2025 15:15:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 22/12/2025 23:25:00. 50 Economy ticket for £48 per person are available. Travel duration is 8h 10m
Itabus	8h 55m	23:35	Rome	Tiburtina Bus Station	08:30	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£48	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 22/12/2025 23:35:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 23/12/2025 08:30:00. 50 Economy ticket for £48 per person are available. Travel duration is 8h 55m
MarinoBus	7h 40m	07:00	Rome	Tiburtina Bus Station	14:40	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Basic	£57	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 22/12/2025 07:00:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 22/12/2025 14:40:00. 50 Basic ticket for £57 per person are available. Travel duration is 7h 40m
FlixBus	7h 30m	23:45	Rome	Tiburtina Bus Station	07:15	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£61	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 22/12/2025 23:45:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 23/12/2025 07:15:00. 50 Economy ticket for £61 per person are available. Travel duration is 7h 30m
MarinoBus	7h 40m	14:30	Rome	Tiburtina Bus Station	22:10	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£62	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 22/12/2025 14:30:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 22/12/2025 22:10:00. 50 Economy ticket for £62 per person are available. Travel duration is 7h 40m

Did you know that if you travel from Rome to Brindisi via Bari, you can save more than £9? You can find the corresponding connections below.
- INFOBUS
  
  7h 40m
  
  0
  
  12:00
  
  Rome
  Tiburtina Bus Station
  
  17:55
  
  Bari
  Central Bus Station
  
  0
  
  Economy
  
  £33
  
  A Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 20/12/2025 12:00:00 to Central Bus Station, Bari (Italy) arriving at 20/12/2025 17:55:00. 50 Economy ticket for £33 per person are available. Travel duration is 5h 55m
- Busbud
  
  1h 40m
  
  0
  
  18:00
  
  Bari
  Bari FS Park Coach Stop
  
  19:40
  
  Brindisi
  Via Giuseppe Maria Galanti Bus Stop
  
  0
  
  Premium Economy
  
  £6
  
  A Bus from Busbud goes from Bari FS Park Coach Stop, Bari (Italy) at 20/12/2025 18:00:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 20/12/2025 19:40:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 1h 40m
Travel time is 0h 10m longer, but you will save £9

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	7h 50m	23:40	Rome	Tiburtina Coach Station	07:30	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Basic	£35	A Bus from Itabus goes from Tiburtina Coach Station, Rome (Italy) at 23/12/2025 23:40:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 24/12/2025 07:30:00. 50 Basic ticket for £35 per person are available. Travel duration is 7h 50m
Itabus	7h 40m	12:00	Rome	Tiburtina Bus Station	19:40	Brindisi	Tribunale Bus Stop	Premium Economy	£42	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 23/12/2025 12:00:00 to Tribunale Bus Stop, Brindisi (Italy) arriving at 23/12/2025 19:40:00. 50 Premium Economy ticket for £42 per person are available. Travel duration is 7h 40m
MarinoBus	7h 40m	14:30	Rome	Tiburtina Bus Station	22:10	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£52	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 23/12/2025 14:30:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 23/12/2025 22:10:00. 50 Economy ticket for £52 per person are available. Travel duration is 7h 40m
MarinoBus	7h 40m	07:00	Rome	Tiburtina Bus Station	14:40	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£56	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 23/12/2025 07:00:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 23/12/2025 14:40:00. 50 Economy ticket for £56 per person are available. Travel duration is 7h 40m
FlixBus	8h 25m	08:20	Rome	Tiburtina Bus Station	16:45	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£74	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 23/12/2025 08:20:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 23/12/2025 16:45:00. 50 Economy ticket for £74 per person are available. Travel duration is 8h 25m

Did you know that if you travel from Rome to Brindisi via Bari, you can save more than £10? You can find the corresponding connections below.
- INFOBUS
  
  10h 25m
  
  0
  
  23:40
  
  Rome
  Tiburtina Bus Station
  
  05:19
  
  Bari
  Central Bus Station
  
  0
  
  Economy
  
  £17
  
  A Bus from INFOBUS goes from Tiburtina Bus Station, Rome (Italy) at 24/12/2025 23:40:00 to Central Bus Station, Bari (Italy) arriving at 25/12/2025 05:19:00. 50 Economy ticket for £17 per person are available. Travel duration is 5h 39m
- FlixBus
  
  1h 55m
  
  0
  
  08:10
  
  Bari
  Central Bus Station
  
  10:05
  
  Brindisi
  Via Giuseppe Maria Galanti Bus Stop
  
  0
  
  Economy
  
  £8
  
  A Bus from FlixBus goes from Central Bus Station, Bari (Italy) at 25/12/2025 08:10:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 25/12/2025 10:05:00. 50 Economy ticket for £8 per person are available. Travel duration is 1h 55m
Travel time is 2h 45m longer, but you will save £10

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Itabus	8h 10m	15:15	Rome	Tiburtina Bus Station	23:25	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£19	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 24/12/2025 15:15:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 24/12/2025 23:25:00. 50 Economy ticket for £19 per person are available. Travel duration is 8h 10m
Itabus	7h 50m	23:40	Rome	Tiburtina Bus Station	07:30	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£19	A Bus from Itabus goes from Tiburtina Bus Station, Rome (Italy) at 24/12/2025 23:40:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 25/12/2025 07:30:00. 50 Economy ticket for £19 per person are available. Travel duration is 7h 50m
FlixBus	7h 30m	23:45	Rome	Tiburtina Bus Station	07:15	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£35	A Bus from FlixBus goes from Tiburtina Bus Station, Rome (Italy) at 24/12/2025 23:45:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 25/12/2025 07:15:00. 50 Economy ticket for £35 per person are available. Travel duration is 7h 30m
MarinoBus	7h 40m	14:30	Rome	Tiburtina Bus Station	22:10	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£42	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 24/12/2025 14:30:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 24/12/2025 22:10:00. 50 Economy ticket for £42 per person are available. Travel duration is 7h 40m
MarinoBus	7h 40m	07:00	Rome	Tiburtina Bus Station	14:40	Brindisi	Via Giuseppe Maria Galanti Bus Stop	Economy	£45	A Bus from MarinoBus goes from Tiburtina Bus Station, Rome (Italy) at 24/12/2025 07:00:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 24/12/2025 14:40:00. 50 Economy ticket for £45 per person are available. Travel duration is 7h 40m

Best Price Offer: The price for the cheapest coach from Rome to Brindisi is £10 on 09/01/2026. Flexible travellers save on ticket prices.

Frequency of bus connections between Rome and Brindisi

See here how frequent the connections between Rome and Brindisi are, during different times and days of the week.

Monday is the busiest day, with more than 63 daily coaches from Rome to Brindisi. Thursday has instead the fewest connections, with only 26 daily coaches between Rome and Brindisi.

The busiest time of the day is the Evening, with 114 coaches from Rome to Brindisi, while Night sees the fewest connections between Rome and Brindisi, with 6 offers.

Facts about coaches from Rome to Brindisi

Compare all providers like Itabus, MarinoBus and FlixBus that travel 45 times every day by bus from Rome to Brindisi in one click! Book your bus ticket from Rome to Brindisi starting from £10!

Cheapest Bus	£10
Fastest Bus	7h 25m
Earliest Coach	07:00
Latest Coach	23:50
Daily Bus Connections	45 Ø
Distance	476.2 km
Coach Companies	Itabus, MarinoBus and FlixBus

Cheapest coach connections from Rome to Brindisi

Every day, 45 buses from 3 coach companies leave Rome for Brindisi: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 18/12/2025 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 15/12

Tuesday 16/12

Wednesday 17/12

Thursday 18/12

£38

Friday 19/12

£46

Saturday 20/12

£38

Sunday 21/12

£42

Monday 22/12

£51

Tuesday 23/12

£42

Wednesday 24/12

£22

Thursday 25/12

£17

Friday 26/12

£30

Saturday 27/12

£17

Sunday 28/12

£17

Monday 29/12

£17

Tuesday 30/12

£30

Wednesday 31/12

£12

Thursday 01/01

£17

Friday 02/01

£17

Saturday 03/01

£17

Sunday 04/01

£17

Monday 05/01

£17

Tuesday 06/01

£17

Wednesday 07/01

£17

Thursday 08/01

£21

Friday 09/01

£10

Saturday 10/01

£12

Sunday 11/01

The cheapest time to travel from Rome to Brindisi

See here on which day and which time of the day you can find the cheapest bus ticket from Rome to Brindisi, for the next 30 days.

With a price starting from £10, Monday is the cheapest day for a coach from Rome to Brindisi. Tuesday instead is the most expensive day with prices starting from £17.

Night is the cheapest day time for bus tickets from Rome to Brindisi, with £10. Morning is the most expensive time of the day with prices starting from £30.

How to save money travelling from Rome to Brindisi

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Rome to Brindisi in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Rome to Brindisi, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Rome to Brindisi are also emptier.

Beloved bus companies from Rome to Brindisi

These are the most booked bus companies between Rome to Brindisi from our users.

Itabus from Rome to Brindisi

Here you will find the key facts about the Itabus bus route Rome to Brindisi:

Cheapest Price	£19
Fastest Coach	7h 40m
Earliest Coach	08:25
Last Coach	23:40
Daily Connections	29 Ø
Found on	18/12/2025

All bus stations and stops in Rome and Brindisi

The map below shows you where to find all the bus stations in Rome and Brindisi.

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Largo Guido Mazzoni 4

Tiburtina Coach Station

Tiburtina Partenze

Vatican City

Via Crescenzio 19

Via Giuseppe Maria Galanti Bus Stop

Via Giuseppe Maria Galanti 8

Central Bus Station

Port

Ospedale "A. Perrino" Bus Stop

Costa Morena Bus Stop

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Rome to Brindisi? Compare all modes of transports from Rome to Brindisi.

Service and Comfort on the bus from Rome to Brindisi

Want to know which seat classes are available on the coaches from Rome to Brindisi? Or which bus companies serve the route Rome to Brindisi? Below you will find answers to your questions.

FAQs about the Rome to Brindisi bus

How much does a Rome - Brindisi coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Rome - Brindisi bus trip is available from £10 and takes 8h 10m. Compare offers and save money!

How much could I save by comparing buses from Rome to Brindisi?

The connection Rome to Brindisi is offered by 3 companies with ticket prices ranging from £10 to £126. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Rome - Brindisi route on average every day?

Each day, the bus route from Rome to Brindisi is offered by roughly 45 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Brindisi from Rome take?

The quickest coach from Rome to Brindisi is provided by FlixBus and takes 7h 25m. Coach tickets for this connection cost £63. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Rome to Brindisi?

The earliest bus to Brindisi departs from Rome at 07:00. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Rome to Brindisi?

The latest bus to Brindisi departs from Rome at 23:50. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Rome - Brindisi route?

Passengers looking to travel from Rome to Brindisi can travel with Itabus, MarinoBus and FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Rome and Brindisi?

You can check all the direct connections between Rome and Brindisi by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Itabus, MarinoBus and FlixBus.

What can I take with me on the bus to Brindisi from Rome?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Rome Brindisi bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Rome Brindisi bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Rome to Brindisi on your planned travel date.

How does CheckMyBus find the best bus deals from Rome to Brindisi?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 45 daily trips between Rome and Brindisi. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Rome to Brindisi?

Prices and availability for 45 trips between Rome and Brindisi change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Rome to Brindisi

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

Premium Economy

A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.

More bus routes to Rome and to Brindisi

Here’s an overview of the most popular bus routes to Rome and to Brindisi. Simply click on the connection of your choice, and you will find all the details about your bus route!