Bus and Coach from Palermo to Brindisi: Compare all prices

Compare all timetables for the bus from Palermo to Brindisi

Here is a selection of the cheapest bus trips from the schedule from Palermo to Brindisi from various bus operators like FlixBus for the next days.

today

tomorrow

Monday

£50

Tuesday

Wednesday

Thursday

Friday

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	20h 24m	21:10	Palermo	Via Tommaso Fazello Bus Stop	17:34	Brindisi	Via Giuseppe Maria Galanti Bus Stop		Economy	£50	A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 09/11/2026 21:10:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 10/11/2026 17:34:00. 50 Economy ticket for £50 per person are available. Travel duration is 20h 24m

Did you know that if you travel from Palermo to Brindisi via Lamezia Terme, you can save more than £19? You can find the corresponding connections below.
- FlixBus
  
  26h 50m
  
  0
  
  11:05
  
  Palermo
  Via Tommaso Fazello Bus Stop
  
  18:50
  
  Lamezia Terme
  Central Station
  
  0
  
  Economy
  
  £17
  
  A Bus from FlixBus goes from Via Tommaso Fazello Bus Stop, Palermo (Italy) at 09/11/2026 11:05:00 to Central Station, Lamezia Terme (Italy) arriving at 09/11/2026 18:50:00. 50 Economy ticket for £17 per person are available. Travel duration is 7h 45m
- FlixBus
  
  6h 49m
  
  0
  
  07:06
  
  Lamezia Terme
  Central Station
  
  13:55
  
  Brindisi
  Via Giuseppe Maria Galanti Bus Stop
  
  0
  
  Economy
  
  £14
  
  A Bus from FlixBus goes from Central Station, Lamezia Terme (Italy) at 10/11/2026 07:06:00 to Via Giuseppe Maria Galanti Bus Stop, Brindisi (Italy) arriving at 10/11/2026 13:55:00. 50 Economy ticket for £14 per person are available. Travel duration is 6h 49m
Travel time is 6h 26m longer, but you will save £19

Best Price Offer: The price for the cheapest coach from Palermo to Brindisi is £39 on 19/11/2026. Flexible travellers save on ticket prices.

Facts about coaches from Palermo to Brindisi

Compare all providers like FlixBus that travel 1 times every day by bus from Palermo to Brindisi in one click! Book your bus ticket from Palermo to Brindisi starting from £39!

Cheapest Bus	£39
Fastest Bus	20h 24m
Earliest Coach	21:10
Latest Coach	21:10
Daily Bus Connections	1 Ø
Distance	483.0 km
Coach Companies	FlixBus

Cheapest coach connections from Palermo to Brindisi

Every day, 1 buses from 1 coach companies leave Palermo for Brindisi: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/11/2026 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 02/11

Tuesday 03/11

Wednesday 04/11

Thursday 05/11

Friday 06/11

Saturday 07/11

Sunday 08/11

Monday 09/11

£50

Tuesday 10/11

Wednesday 11/11

Thursday 12/11

Friday 13/11

Saturday 14/11

Sunday 15/11

Monday 16/11

Tuesday 17/11

Wednesday 18/11

Thursday 19/11

£39

Friday 20/11

£53

Saturday 21/11

Sunday 22/11

Monday 23/11

Tuesday 24/11

Wednesday 25/11

Thursday 26/11

Friday 27/11

£48

Saturday 28/11

Sunday 29/11

How to save money travelling from Palermo to Brindisi

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Palermo to Brindisi in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Palermo to Brindisi, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Palermo to Brindisi are also emptier.

All bus stations and stops in Palermo and Brindisi

The map below shows you where to find all the bus stations in Palermo and Brindisi.

Oreto Orsi Bus Stop

Via Oreto 389

Piazza Cairoli Bus Station

Piazza Cairoli Piazza Cairoli

Piazza Indipendenza Station

Piazza Indipendenza Palazzo Reale

Via Tommaso Fazello Bus Stop

Via Tommaso Fazello

Via della Libertà

Via della Libertà 163

Via Giuseppe Maria Galanti Bus Stop

Via Giuseppe Maria Galanti 8

Central Bus Station

Port

Costa Morena Bus Stop

Viale Arno Bus Stop

Viale Arno

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Palermo to Brindisi? Compare all modes of transports from Palermo to Brindisi.

Service and Comfort on the bus from Palermo to Brindisi

Want to know which seat classes are available on the coaches from Palermo to Brindisi? Or which bus companies serve the route Palermo to Brindisi? Below you will find answers to your questions.

FAQs about the Palermo to Brindisi bus

How much does a Palermo - Brindisi coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Palermo - Brindisi bus trip is available from £39 and takes 20h 24m. Compare offers and save money!

How much could I save by comparing buses from Palermo to Brindisi?

The connection Palermo to Brindisi is offered by 1 companies with ticket prices ranging from £39 to £50. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Palermo - Brindisi route on average every day?

Each day, the bus route from Palermo to Brindisi is offered by roughly 1 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Brindisi from Palermo take?

The quickest coach from Palermo to Brindisi is provided by FlixBus and takes 20h 24m. Coach tickets for this connection cost £50. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Palermo to Brindisi?

The earliest bus to Brindisi departs from Palermo at 21:10. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Palermo to Brindisi?

The latest bus to Brindisi departs from Palermo at 21:10. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Palermo - Brindisi route?

Passengers looking to travel from Palermo to Brindisi can travel with FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Palermo and Brindisi?

You can check all the direct connections between Palermo and Brindisi by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the bus to Brindisi from Palermo?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Palermo Brindisi bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Palermo Brindisi bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Palermo to Brindisi on your planned travel date.

How does CheckMyBus find the best bus deals from Palermo to Brindisi?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Palermo and Brindisi. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Palermo to Brindisi?

Prices and availability for 1 trips between Palermo and Brindisi change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Palermo to Brindisi

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Palermo and to Brindisi

Here’s an overview of the most popular bus routes to Palermo and to Brindisi. Simply click on the connection of your choice, and you will find all the details about your bus route!