Bus and Coach from Siracusa to Rome: Compare all prices

Compare all timetables for the bus from Siracusa to Rome

Here is a selection of the cheapest bus trips from the schedule from Siracusa to Rome from various bus operators like FlixBus for the next days.

today

tomorrow

Saturday

Sunday

£79

Monday

£53

Tuesday

Wednesday

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	13h 30m	17:20	Siracusa	Corso Umberto Bus Station	06:50	Rome	Tiburtina Bus Station	Economy	£79	A Bus from FlixBus goes from Corso Umberto Bus Station, Siracusa (Italy) at 21/06/2026 17:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/06/2026 06:50:00. 50 Economy ticket for £79 per person are available. Travel duration is 13h 30m
FlixBus	18h 30m	17:20	Siracusa	Corso Umberto Bus Station	11:50	Rome	Anagnina Bus Station	Economy	£84	A Bus from FlixBus goes from Corso Umberto Bus Station, Siracusa (Italy) at 21/06/2026 17:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 22/06/2026 11:50:00. 50 Economy ticket for £84 per person are available. Travel duration is 18h 30m
FlixBus	14h 15m	07:15	Siracusa	Corso Umberto Bus Station	21:30	Rome	Tiburtina Bus Station	Economy	£91	A Bus from FlixBus goes from Corso Umberto Bus Station, Siracusa (Italy) at 21/06/2026 07:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/06/2026 21:30:00. 50 Economy ticket for £91 per person are available. Travel duration is 14h 15m

Did you know that if you travel from Siracusa to Rome via Catania, you can save more than £54? You can find the corresponding connections below.
- Interbus
  
  12h 45m
  
  0
  
  19:00
  
  Siracusa
  Scala Greca Coach Station
  
  20:02
  
  Catania
  Piazza Borsellino Bus Stop
  
  0
  
  Economy
  
  £5
  
  A Bus from Interbus goes from Scala Greca Coach Station, Siracusa (Italy) at 20/06/2026 19:00:00 to Piazza Borsellino Bus Stop, Catania (Italy) arriving at 20/06/2026 20:02:00. 50 Economy ticket for £5 per person are available. Travel duration is 1h 2m
- Itabus
  
  11h 30m
  
  0
  
  20:15
  
  Catania
  Central Bus Station
  
  07:45
  
  Rome
  Tiburtina Bus Station
  
  0
  
  Premium Economy
  
  £20
  
  A Bus from Itabus goes from Central Bus Station, Catania (Italy) at 20/06/2026 20:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/06/2026 07:45:00. 50 Premium Economy ticket for £20 per person are available. Travel duration is 11h 30m
Travel Time is 0h 45m shorter, and you will save £54

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	18h 30m	17:20	Siracusa	Corso Umberto Bus Station	11:50	Rome	Anagnina Bus Station	Economy	£53	A Bus from FlixBus goes from Corso Umberto Bus Station, Siracusa (Italy) at 22/06/2026 17:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 23/06/2026 11:50:00. 50 Economy ticket for £53 per person are available. Travel duration is 18h 30m
FlixBus	13h 30m	17:20	Siracusa	Corso Umberto Bus Station	06:50	Rome	Tiburtina Bus Station	Economy	£60	A Bus from FlixBus goes from Corso Umberto Bus Station, Siracusa (Italy) at 22/06/2026 17:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/06/2026 06:50:00. 50 Economy ticket for £60 per person are available. Travel duration is 13h 30m
FlixBus	14h 15m	07:15	Siracusa	Corso Umberto Bus Station	21:30	Rome	Tiburtina Bus Station	Economy	£68	A Bus from FlixBus goes from Corso Umberto Bus Station, Siracusa (Italy) at 22/06/2026 07:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/06/2026 21:30:00. 50 Economy ticket for £68 per person are available. Travel duration is 14h 15m

Did you know that if you travel from Siracusa to Rome via Catania, you can save more than £29? You can find the corresponding connections below.
- Interbus
  
  18h 5m
  
  0
  
  20:15
  
  Siracusa
  Scala Greca Coach Station
  
  21:17
  
  Catania
  Piazza Borsellino Bus Stop
  
  0
  
  Economy
  
  £5
  
  A Bus from Interbus goes from Scala Greca Coach Station, Siracusa (Italy) at 23/06/2026 20:15:00 to Piazza Borsellino Bus Stop, Catania (Italy) arriving at 23/06/2026 21:17:00. 50 Economy ticket for £5 per person are available. Travel duration is 1h 2m
- Itabus
  
  16h 10m
  
  0
  
  22:10
  
  Catania
  Central Bus Station
  
  14:20
  
  Rome
  Tiburtina Coach Station
  
  0
  
  Economy
  
  £19
  
  A Bus from Itabus goes from Central Bus Station, Catania (Italy) at 23/06/2026 22:10:00 to Tiburtina Coach Station, Rome (Italy) arriving at 24/06/2026 14:20:00. 50 Economy ticket for £19 per person are available. Travel duration is 16h 10m
Travel time is 4h 35m longer, but you will save £29

Best Price Offer: The price for the cheapest coach from Siracusa to Rome is £42 on 09/07/2026. Flexible travellers save on ticket prices.

Frequency of bus connections between Siracusa and Rome

See here how frequent the connections between Siracusa and Rome are, during different times and days of the week.

Monday is the busiest day, with more than 3 daily coaches from Siracusa to Rome. Monday has instead the fewest connections, with only 3 daily coaches between Siracusa and Rome.

The busiest time of the day is the Afternoon, with 4 coaches from Siracusa to Rome, while Morning sees the fewest connections between Siracusa and Rome, with 2 offers.

Facts about coaches from Siracusa to Rome

Compare all providers like FlixBus that travel 3 times every day by bus from Siracusa to Rome in one click! Book your bus ticket from Siracusa to Rome starting from £42!

Cheapest Bus	£42
Fastest Bus	13h 30m
Earliest Coach	07:15
Latest Coach	17:20
Daily Bus Connections	3 Ø
Distance	587.5 km
Coach Companies	FlixBus

Cheapest coach connections from Siracusa to Rome

Every day, 3 buses from 1 coach companies leave Siracusa for Rome: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 18/06/2026 and for the following days.

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday

Monday 15/06

Tuesday 16/06

Wednesday 17/06

Thursday 18/06

Friday 19/06

Saturday 20/06

Sunday 21/06

£79

Monday 22/06

£53

Tuesday 23/06

Wednesday 24/06

Thursday 25/06

£54

Friday 26/06

£65

Saturday 27/06

Sunday 28/06

£76

Monday 29/06

Tuesday 30/06

Wednesday 01/07

Thursday 02/07

£52

Friday 03/07

Saturday 04/07

Sunday 05/07

Monday 06/07

Tuesday 07/07

£59

Wednesday 08/07

Thursday 09/07

£42

Friday 10/07

£47

Saturday 11/07

Sunday 12/07

The cheapest time to travel from Siracusa to Rome

See here on which day and which time of the day you can find the cheapest bus ticket from Siracusa to Rome, for the next 30 days.

With a price starting from £50, Monday is the cheapest day for a coach from Siracusa to Rome. Sunday instead is the most expensive day with prices starting from £65.

Afternoon is the cheapest day time for bus tickets from Siracusa to Rome, with £53. Morning is the most expensive time of the day with prices starting from £68.

How to save money travelling from Siracusa to Rome

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Siracusa to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Siracusa to Rome, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Siracusa to Rome are also emptier.

All bus stations and stops in Siracusa and Rome

The map below shows you where to find all the bus stations in Siracusa and Rome.

Corso Umberto Bus Station

Corso Umberto 196

Scala Greca Coach Station

Viale Scala Greca 246

Corso Gelone

Corso Gelone 50

Via Von Platen

Fontane Bianche

Anagnina Bus Station

Piazzale della Stazione Anagnina

Termini Bus Station

Piazza dei Cinquecento 64

Tiburtina Bus Station

Largo Guido Mazzoni 4

Tiburtina Coach Station

Tiburtina Partenze

Fori Imperiali Bus Stop

Service and Comfort on the bus from Siracusa to Rome

Want to know which seat classes are available on the coaches from Siracusa to Rome? Or which bus companies serve the route Siracusa to Rome? Below you will find answers to your questions.

FAQs about the Siracusa to Rome bus

How much does a Siracusa - Rome coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Siracusa - Rome bus trip is available from £42 and takes 18h 30m. Compare offers and save money!

How much could I save by comparing buses from Siracusa to Rome?

The connection Siracusa to Rome is offered by 1 companies with ticket prices ranging from £42 to £91. Therefore, we suggest booking your ticket as soon as possible to ensure you will get the cheapest ticket price.

How many connections are available for the Siracusa - Rome route on average every day?

Each day, the bus route from Siracusa to Rome is offered by roughly 3 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Rome from Siracusa take?

The quickest coach from Siracusa to Rome is provided by FlixBus and takes 13h 30m. Coach tickets for this connection cost £79. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Siracusa to Rome?

The earliest bus to Rome departs from Siracusa at 07:15. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Siracusa to Rome?

The latest bus to Rome departs from Siracusa at 17:20. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Siracusa - Rome route?

Passengers looking to travel from Siracusa to Rome can travel with FlixBus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Siracusa and Rome?

You can check all the direct connections between Siracusa and Rome by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the bus to Rome from Siracusa?

Depending on which provider you travel with, what you are allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Siracusa Rome bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Siracusa Rome bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Siracusa to Rome on your planned travel date.

How does CheckMyBus find the best bus deals from Siracusa to Rome?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Siracusa and Rome. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Siracusa to Rome?

Prices and availability for 3 trips between Siracusa and Rome change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Siracusa to Rome

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Siracusa and to Rome

Here’s an overview of the most popular bus routes to Siracusa and to Rome. Simply click on the connection of your choice, and you will find all the details about your bus route!