Which bus from Prague to Rome is the best?
Check the bus schedule for Prague to Rome. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or RegioJet. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 20m | 22:20 | Prague | Roztyly | 21:40 | Rome | Anagnina Bus Station | Economy | £71 |
A Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 05/12/2025 22:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 06/12/2025 21:40:00. 50 Economy ticket for £71 per person are available. Travel duration is 23h 20m
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| FlixBus | 24h 45m | 22:15 | Prague | Na Knížecí Station | 23:00 | Rome | Tiburtina Bus Station | Economy | £79 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 05/12/2025 22:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/12/2025 23:00:00. 50 Economy ticket for £79 per person are available. Travel duration is 24h 45m
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| FlixBus | 28h 15m | 18:45 | Prague | Wilsonova Coach Station | 23:00 | Rome | Tiburtina Bus Station | Economy | £80 |
A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 05/12/2025 18:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/12/2025 23:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 28h 15m
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| FlixBus | 23h 10m | 23:50 | Prague | Wilsonova Coach Station | 23:00 | Rome | Tiburtina Bus Station | Economy | £80 |
A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 05/12/2025 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/12/2025 23:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 23h 10m
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| FlixBus | 23h 25m | 23:35 | Prague | ÚAN Florenc | 23:00 | Rome | Tiburtina Bus Station | Economy | £80 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 05/12/2025 23:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/12/2025 23:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 23h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 22h 50m | 14:30 | Prague | Černý Most | 13:20 | Rome | Tiburtina Bus Station | Economy | £66 |
A Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 06/12/2025 14:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 07/12/2025 13:20:00. 50 Economy ticket for £66 per person are available. Travel duration is 22h 50m
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| FlixBus | 19h 35m | 17:45 | Prague | Na Knížecí Station | 13:20 | Rome | Tiburtina Bus Station | Economy | £66 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 06/12/2025 17:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 07/12/2025 13:20:00. 50 Economy ticket for £66 per person are available. Travel duration is 19h 35m
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| FlixBus | 22h 15m | 15:05 | Prague | Zličín | 13:20 | Rome | Tiburtina Bus Station | Economy | £66 |
A Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 06/12/2025 15:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 07/12/2025 13:20:00. 50 Economy ticket for £66 per person are available. Travel duration is 22h 15m
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| FlixBus | 24h 30m | 12:50 | Prague | Hradčanská | 13:20 | Rome | Tiburtina Bus Station | Economy | £66 |
A Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 06/12/2025 12:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 07/12/2025 13:20:00. 50 Economy ticket for £66 per person are available. Travel duration is 24h 30m
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| FlixBus | 23h 25m | 12:50 | Prague | ÚAN Florenc | 12:15 | Rome | Anagnina Bus Station | Economy | £66 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 06/12/2025 12:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 07/12/2025 12:15:00. 50 Economy ticket for £66 per person are available. Travel duration is 23h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 20m | 22:20 | Prague | Roztyly | 21:40 | Rome | Anagnina Bus Station | Economy | £85 |
A Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 07/12/2025 22:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 08/12/2025 21:40:00. 50 Economy ticket for £85 per person are available. Travel duration is 23h 20m
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| FlixBus | 20h 30m | 02:30 | Prague | Wilsonova Coach Station | 23:00 | Rome | Tiburtina Bus Station | Economy | £86 |
A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 07/12/2025 02:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 07/12/2025 23:00:00. 50 Economy ticket for £86 per person are available. Travel duration is 20h 30m
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| FlixBus | 23h 5m | 10:25 | Prague | Na Knížecí Station | 09:30 | Rome | Tiburtina Bus Station | Economy | £86 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 07/12/2025 10:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 08/12/2025 09:30:00. 50 Economy ticket for £86 per person are available. Travel duration is 23h 5m
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| FlixBus | 19h 35m | 17:45 | Prague | Na Knížecí Station | 13:20 | Rome | Tiburtina Bus Station | Economy | £87 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 07/12/2025 17:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 08/12/2025 13:20:00. 50 Economy ticket for £87 per person are available. Travel duration is 19h 35m
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| FlixBus | 24h 25m | 12:55 | Prague | Zličín | 13:20 | Rome | Tiburtina Bus Station | Economy | £87 |
A Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 07/12/2025 12:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 08/12/2025 13:20:00. 50 Economy ticket for £87 per person are available. Travel duration is 24h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RegioJet | 20h 15m | 18:30 | Prague | ÚAN Florenc | 14:45 | Rome | Tiburtina Bus Station | Economy | £56 |
A Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 08/12/2025 18:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 09/12/2025 14:45:00. 50 Economy ticket for £56 per person are available. Travel duration is 20h 15m
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| FlixBus | 23h 10m | 23:50 | Prague | Wilsonova Coach Station | 23:00 | Rome | Tiburtina Bus Station | Economy | £70 |
A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 08/12/2025 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 09/12/2025 23:00:00. 50 Economy ticket for £70 per person are available. Travel duration is 23h 10m
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| FlixBus | 24h 45m | 22:15 | Prague | Na Knížecí Station | 23:00 | Rome | Tiburtina Bus Station | Economy | £70 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 08/12/2025 22:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 09/12/2025 23:00:00. 50 Economy ticket for £70 per person are available. Travel duration is 24h 45m
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| FlixBus | 23h 25m | 23:35 | Prague | ÚAN Florenc | 23:00 | Rome | Tiburtina Bus Station | Economy | £70 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 08/12/2025 23:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 09/12/2025 23:00:00. 50 Economy ticket for £70 per person are available. Travel duration is 23h 25m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 35m | 09:55 | Prague | Zličín | 09:30 | Rome | Tiburtina Bus Station | Economy | £70 |
A Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 09/12/2025 09:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 10/12/2025 09:30:00. 50 Economy ticket for £70 per person are available. Travel duration is 23h 35m
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| FlixBus | 19h 35m | 17:45 | Prague | Na Knížecí Station | 13:20 | Rome | Tiburtina Bus Station | Economy | £71 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 09/12/2025 17:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 10/12/2025 13:20:00. 50 Economy ticket for £71 per person are available. Travel duration is 19h 35m
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| FlixBus | 24h 45m | 22:15 | Prague | Na Knížecí Station | 23:00 | Rome | Tiburtina Bus Station | Economy | £71 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 09/12/2025 22:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 10/12/2025 23:00:00. 50 Economy ticket for £71 per person are available. Travel duration is 24h 45m
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| FlixBus | 24h 20m | 17:45 | Prague | Na Knížecí Station | 18:05 | Rome | Anagnina Bus Station | Economy | £71 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 09/12/2025 17:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 10/12/2025 18:05:00. 50 Economy ticket for £71 per person are available. Travel duration is 24h 20m
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| FlixBus | 20h 40m | 21:25 | Prague | ÚAN Florenc | 18:05 | Rome | Anagnina Bus Station | Economy | £71 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 09/12/2025 21:25:00 to Anagnina Bus Station, Rome (Italy) arriving at 10/12/2025 18:05:00. 50 Economy ticket for £71 per person are available. Travel duration is 20h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 24h 20m | 09:40 | Prague | Na Knížecí Station | 10:00 | Rome | Tiburtina Bus Station | Economy | £69 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 10/12/2025 09:40:00 to Tiburtina Bus Station, Rome (Italy) arriving at 11/12/2025 10:00:00. 50 Economy ticket for £69 per person are available. Travel duration is 24h 20m
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| FlixBus | 22h 50m | 14:30 | Prague | Černý Most | 13:20 | Rome | Tiburtina Bus Station | Economy | £69 |
A Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 10/12/2025 14:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 11/12/2025 13:20:00. 50 Economy ticket for £69 per person are available. Travel duration is 22h 50m
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| FlixBus | 20h 30m | 17:35 | Prague | Wilsonova Coach Station | 14:05 | Rome | Tiburtina Bus Station | Economy | £70 |
A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 10/12/2025 17:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 11/12/2025 14:05:00. 50 Economy ticket for £70 per person are available. Travel duration is 20h 30m
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| FlixBus | 20h 45m | 17:20 | Prague | ÚAN Florenc | 14:05 | Rome | Tiburtina Bus Station | Economy | £70 |
A Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 10/12/2025 17:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 11/12/2025 14:05:00. 50 Economy ticket for £70 per person are available. Travel duration is 20h 45m
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| FlixBus | 25h 0m | 08:30 | Prague | Roztyly | 09:30 | Rome | Tiburtina Bus Station | Economy | £71 |
A Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 10/12/2025 08:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 11/12/2025 09:30:00. 50 Economy ticket for £71 per person are available. Travel duration is 25h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 50m | 09:40 | Prague | Na Knížecí Station | 09:30 | Rome | Tiburtina Bus Station | Economy | £65 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 11/12/2025 09:40:00 to Tiburtina Bus Station, Rome (Italy) arriving at 12/12/2025 09:30:00. 50 Economy ticket for £65 per person are available. Travel duration is 23h 50m
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| FlixBus | 20h 30m | 02:30 | Prague | Wilsonova Coach Station | 23:00 | Rome | Tiburtina Bus Station | Economy | £66 |
A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 11/12/2025 02:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 11/12/2025 23:00:00. 50 Economy ticket for £66 per person are available. Travel duration is 20h 30m
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| FlixBus | 27h 40m | 05:50 | Prague | Wilsonova Coach Station | 09:30 | Rome | Tiburtina Bus Station | Economy | £66 |
A Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 11/12/2025 05:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 12/12/2025 09:30:00. 50 Economy ticket for £66 per person are available. Travel duration is 27h 40m
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| FlixBus | 19h 35m | 17:45 | Prague | Na Knížecí Station | 13:20 | Rome | Tiburtina Bus Station | Economy | £66 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 11/12/2025 17:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 12/12/2025 13:20:00. 50 Economy ticket for £66 per person are available. Travel duration is 19h 35m
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| FlixBus | 26h 35m | 09:40 | Prague | Na Knížecí Station | 12:15 | Rome | Anagnina Bus Station | Economy | £66 |
A Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 11/12/2025 09:40:00 to Anagnina Bus Station, Rome (Italy) arriving at 12/12/2025 12:15:00. 50 Economy ticket for £66 per person are available. Travel duration is 26h 35m
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Best Price Offer: The price for the cheapest coach from Prague to Rome is £56 on 08/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Prague and Rome?
All facts for Prague to Rome bus at a glance
Compare all coach operators like FlixBus and RegioJet that travel daily 33 times by bus from Prague to Rome in one click. Book your Prague to Rome bus ticket starting from £56!
| Cheapest Bus | £56 |
| Fastest Bus | 19h 15m |
| Earliest Coach | 02:30 |
| Latest Coach | 23:50 |
| Daily Bus Connections | 33 Ø |
| Distance | 921.0 km |
| Coach Companies | FlixBus and RegioJet |
What are the cheapest coach tickets from Prague to Rome?
Every day, 33 buses from 2 coach companies leave Prague for Rome. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Prague to Rome
How to save money travelling from Prague to Rome
Book the ticket from Prague to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Prague to Rome, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Prague to Rome are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Prague and Rome
Here is a map with all coach stations in Prague and Rome. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Prague to Rome
FAQs for Prague to Rome bus
How much does a Prague Rome coach trip cost?
How much could I save by comparing buses from Prague to Rome?
How many connections are available for the Prague Rome route on average every day?
How long does a bus to Rome from Prague take?
What time is the first bus from Prague to Rome?
What time is the last coach from Prague to Rome?
Which bus companies serve the Prague Rome route?
Is there a direct bus between Prague and Rome?
What can I take with me on the bus to Rome from Prague?
What equipment is available for the Prague Rome bus route?
Available seat classes which are offered on the bus route Prague to Rome
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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