What is the best way to travel from Prague to Rome?
Looking for a trip? Check and compare all the available Flights and Buses to Rome from Prague. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Rome from Prague?
You can reach Rome with just £40 by taking a Flight from Skyscanner, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Skyscanner1h 50m019:10Prague AirportPrague Airport - T1/221:00Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 19:10:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 05/02/2026 21:00:00. 50 Economy ticket for £59 per person are available. Travel duration is 1h 50m
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Astra Airlines9h 20m012:15Prague AirportPrague Airport - T1/221:35Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Astra Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 12:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 05/02/2026 21:35:00. 50 Economy ticket for £79 per person are available. Travel duration is 9h 20m
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Buzz4h 40m016:15Prague AirportPrague Airport - T1/220:55Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 16:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 05/02/2026 20:55:00. 50 Economy ticket for £82 per person are available. Travel duration is 4h 40m
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Air Bagan6h 25m018:50Prague AirportPrague Airport - T1/201:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 18:50:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 06/02/2026 01:15:00. 50 Economy ticket for £108 per person are available. Travel duration is 6h 25m
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Norwegian Air International23h 5m013:45Prague AirportPrague Airport - T1/212:50Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Norwegian Air International goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 13:45:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 06/02/2026 12:50:00. 50 Economy ticket for £111 per person are available. Travel duration is 23h 5m
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Fly One16h 0m019:00Prague AirportPrague Airport11:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Fly One goes from Prague Airport, Prague Airport (Czech Republic) at 05/02/2026 19:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 06/02/2026 11:00:00. 50 Economy ticket for £117 per person are available. Travel duration is 16h 0m
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FlixBus24h 15m022:45Prague AirportPrague Airport - T1/223:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 22:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/02/2026 23:00:00. 50 Economy ticket for £67 per person are available. Travel duration is 24h 15m
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FlixBus20h 40m012:50PragueÚAN Florenc09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 05/02/2026 12:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/02/2026 09:30:00. 50 Economy ticket for £78 per person are available. Travel duration is 20h 40m
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FlixBus20h 25m013:05PragueWilsonova Coach Station09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 05/02/2026 13:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/02/2026 09:30:00. 50 Economy ticket for £78 per person are available. Travel duration is 20h 25m
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FlixBus22h 50m014:30PragueČerný Most13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 05/02/2026 14:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/02/2026 13:20:00. 50 Economy ticket for £78 per person are available. Travel duration is 22h 50m
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FlixBus23h 25m023:35PragueÚAN Florenc23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 05/02/2026 23:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/02/2026 23:00:00. 50 Economy ticket for £79 per person are available. Travel duration is 23h 25m
Cheapest Flights Thursday
Cheapest Buses Thursday
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 06/02/2026 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 07/02/2026 18:00:00. 50 Economy ticket for £60 per person are available. Travel duration is 23h 10m
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FlixBus24h 15m022:45Prague AirportPrague Airport - T1/223:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 06/02/2026 22:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 07/02/2026 23:00:00. 50 Economy ticket for £66 per person are available. Travel duration is 24h 15m
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FlixBus27h 45m011:20Prague AirportPrague Airport - T1/215:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 06/02/2026 11:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 07/02/2026 15:05:00. 50 Economy ticket for £66 per person are available. Travel duration is 27h 45m
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FlixBus23h 10m023:50PragueWilsonova Coach Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 06/02/2026 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 07/02/2026 23:00:00. 50 Economy ticket for £68 per person are available. Travel duration is 23h 10m
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FlixBus23h 50m018:55PragueZličín18:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 06/02/2026 18:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 07/02/2026 18:45:00. 50 Economy ticket for £68 per person are available. Travel duration is 23h 50m
Cheapest Buses Friday
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 08/02/2026 18:00:00. 50 Economy ticket for £58 per person are available. Travel duration is 23h 10m
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FlixBus21h 20m017:45PragueNa Knížecí Station15:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 07/02/2026 17:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 08/02/2026 15:05:00. 50 Economy ticket for £59 per person are available. Travel duration is 21h 20m
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FlixBus19h 35m017:45PragueNa Knížecí Station13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 07/02/2026 17:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 08/02/2026 13:20:00. 50 Economy ticket for £60 per person are available. Travel duration is 19h 35m
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FlixBus20h 0m021:25PragueÚAN Florenc17:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 07/02/2026 21:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 08/02/2026 17:25:00. 50 Economy ticket for £60 per person are available. Travel duration is 20h 0m
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FlixBus20h 35m021:25PragueÚAN Florenc18:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 07/02/2026 21:25:00 to Anagnina Bus Station, Rome (Italy) arriving at 08/02/2026 18:00:00. 50 Economy ticket for £60 per person are available. Travel duration is 20h 35m
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Vueling Airlines13h 55m021:10Prague AirportPrague Airport11:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 07/02/2026 21:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 08/02/2026 11:05:00. 50 Economy ticket for £95 per person are available. Travel duration is 13h 55m
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Smartwings16h 20m006:40Prague AirportPrague Airport23:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 07/02/2026 06:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 07/02/2026 23:00:00. 50 Economy ticket for £100 per person are available. Travel duration is 16h 20m
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EasyJet Airline7h 40m009:00Prague AirportPrague Airport16:40Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 07/02/2026 09:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 07/02/2026 16:40:00. 50 Economy ticket for £131 per person are available. Travel duration is 7h 40m
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Iberia10h 30m021:10Prague AirportPrague Airport07:40Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Iberia goes from Prague Airport, Prague Airport (Czech Republic) at 07/02/2026 21:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 08/02/2026 07:40:00. 50 Economy ticket for £139 per person are available. Travel duration is 10h 30m
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Lufthansa4h 45m006:15Prague AirportPrague Airport11:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Lufthansa goes from Prague Airport, Prague Airport (Czech Republic) at 07/02/2026 06:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 07/02/2026 11:00:00. 50 Economy ticket for £151 per person are available. Travel duration is 4h 45m
Cheapest Buses Saturday
Cheapest Flights Saturday
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FlixBus22h 35m018:50Prague AirportPrague Airport - T1/217:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 18:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 09/02/2026 17:25:00. 50 Economy ticket for £55 per person are available. Travel duration is 22h 35m
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 09/02/2026 18:00:00. 50 Economy ticket for £55 per person are available. Travel duration is 23h 10m
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FlixBus21h 50m017:15PragueÚAN Florenc15:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 08/02/2026 17:15:00 to Anagnina Bus Station, Rome (Italy) arriving at 09/02/2026 15:05:00. 50 Economy ticket for £57 per person are available. Travel duration is 21h 50m
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FlixBus21h 35m017:30PragueWilsonova Coach Station15:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 08/02/2026 17:30:00 to Anagnina Bus Station, Rome (Italy) arriving at 09/02/2026 15:05:00. 50 Economy ticket for £57 per person are available. Travel duration is 21h 35m
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FlixBus20h 35m021:25PragueÚAN Florenc18:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 08/02/2026 21:25:00 to Anagnina Bus Station, Rome (Italy) arriving at 09/02/2026 18:00:00. 50 Economy ticket for £58 per person are available. Travel duration is 20h 35m
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Smartwings1h 55m011:20Prague AirportPrague Airport - T1/213:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 11:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 08/02/2026 13:15:00. 50 Economy ticket for £64 per person are available. Travel duration is 1h 55m
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Buzz14h 15m017:10Prague AirportPrague Airport - T1/207:25Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 17:10:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 09/02/2026 07:25:00. 50 Economy ticket for £74 per person are available. Travel duration is 14h 15m
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Buzz14h 50m017:10Prague AirportPrague Airport - T1/208:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 17:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 09/02/2026 08:00:00. 50 Economy ticket for £79 per person are available. Travel duration is 14h 50m
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Buzz1h 50m006:20Prague AirportPrague Airport - T1/208:10Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 06:20:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 08/02/2026 08:10:00. 50 Economy ticket for £98 per person are available. Travel duration is 1h 50m
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Air Serbia11h 45m020:30Prague AirportPrague Airport08:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Serbia goes from Prague Airport, Prague Airport (Czech Republic) at 08/02/2026 20:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 09/02/2026 08:15:00. 50 Economy ticket for £99 per person are available. Travel duration is 11h 45m
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LC Perú1h 55m022:55Prague AirportPrague Airport - T1/200:50Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 22:55:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 09/02/2026 00:50:00. 50 Economy ticket for £100 per person are available. Travel duration is 1h 55m
Cheapest Buses Sunday
Cheapest Flights Sunday
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FlixBus20h 0m021:25PragueÚAN Florenc17:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 09/02/2026 21:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 10/02/2026 17:25:00. 50 Economy ticket for £52 per person are available. Travel duration is 20h 0m
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 09/02/2026 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 10/02/2026 18:00:00. 50 Economy ticket for £52 per person are available. Travel duration is 23h 10m
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FlixBus22h 35m018:50Prague AirportPrague Airport - T1/217:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 09/02/2026 18:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 10/02/2026 17:25:00. 50 Economy ticket for £52 per person are available. Travel duration is 22h 35m
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FlixBus20h 35m021:25PragueÚAN Florenc18:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 09/02/2026 21:25:00 to Anagnina Bus Station, Rome (Italy) arriving at 10/02/2026 18:00:00. 50 Economy ticket for £53 per person are available. Travel duration is 20h 35m
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FlixBus20h 25m013:05PragueWilsonova Coach Station09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 09/02/2026 13:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 10/02/2026 09:30:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 25m
Cheapest Buses Monday
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Skyscanner1h 50m008:30Prague AirportPrague Airport - T1/210:20Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 08:30:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 10/02/2026 10:20:00. 50 Economy ticket for £40 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m014:35Prague AirportPrague Airport - T1/216:25Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 14:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 10/02/2026 16:25:00. 50 Economy ticket for £51 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m009:25Prague AirportPrague Airport - T1/211:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 10/02/2026 11:20:00. 50 Economy ticket for £52 per person are available. Travel duration is 1h 55m
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Buzz17h 50m017:30Prague AirportPrague Airport - T1/211:20Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 17:30:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 11/02/2026 11:20:00. 50 Economy ticket for £55 per person are available. Travel duration is 17h 50m
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Buzz17h 10m017:30Prague AirportPrague Airport - T1/210:40Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 17:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 11/02/2026 10:40:00. 50 Economy ticket for £58 per person are available. Travel duration is 17h 10m
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Ryanair8h 55m011:35Prague AirportPrague Airport - T1/220:30Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 11:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 10/02/2026 20:30:00. 50 Economy ticket for £70 per person are available. Travel duration is 8h 55m
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FlixBus24h 40m008:50Prague AirportPrague Airport - T1/209:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 08:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 11/02/2026 09:30:00. 50 Economy ticket for £47 per person are available. Travel duration is 24h 40m
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FlixBus23h 15m018:50Prague AirportPrague Airport - T1/218:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 11/02/2026 18:05:00. 50 Economy ticket for £51 per person are available. Travel duration is 23h 15m
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FlixBus23h 20m019:25PragueZličín18:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 10/02/2026 19:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 11/02/2026 18:45:00. 50 Economy ticket for £56 per person are available. Travel duration is 23h 20m
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FlixBus26h 0m011:20Prague AirportPrague Airport - T1/213:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 11:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 11/02/2026 13:20:00. 50 Economy ticket for £56 per person are available. Travel duration is 26h 0m
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FlixBus22h 35m018:50Prague AirportPrague Airport - T1/217:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 18:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 11/02/2026 17:25:00. 50 Economy ticket for £56 per person are available. Travel duration is 22h 35m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
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FlixBus24h 40m008:50Prague AirportPrague Airport - T1/209:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 11/02/2026 08:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 12/02/2026 09:30:00. 50 Economy ticket for £49 per person are available. Travel duration is 24h 40m
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FlixBus27h 40m005:50PragueWilsonova Coach Station09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 11/02/2026 05:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 12/02/2026 09:30:00. 50 Economy ticket for £52 per person are available. Travel duration is 27h 40m
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FlixBus23h 50m009:40PragueNa Knížecí Station09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 11/02/2026 09:40:00 to Tiburtina Bus Station, Rome (Italy) arriving at 12/02/2026 09:30:00. 50 Economy ticket for £52 per person are available. Travel duration is 23h 50m
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FlixBus24h 20m017:45PragueNa Knížecí Station18:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 11/02/2026 17:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 12/02/2026 18:05:00. 50 Economy ticket for £52 per person are available. Travel duration is 24h 20m
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FlixBus27h 35m014:30PragueČerný Most18:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 11/02/2026 14:30:00 to Anagnina Bus Station, Rome (Italy) arriving at 12/02/2026 18:05:00. 50 Economy ticket for £53 per person are available. Travel duration is 27h 35m
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Iberia11h 45m012:30Prague AirportPrague Airport00:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Iberia goes from Prague Airport, Prague Airport (Czech Republic) at 11/02/2026 12:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/02/2026 00:15:00. 50 Economy ticket for £91 per person are available. Travel duration is 11h 45m
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Air Serbia11h 45m020:30Prague AirportPrague Airport08:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Serbia goes from Prague Airport, Prague Airport (Czech Republic) at 11/02/2026 20:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/02/2026 08:15:00. 50 Economy ticket for £99 per person are available. Travel duration is 11h 45m
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EasyJet Airline8h 45m014:45Prague AirportPrague Airport23:30Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 11/02/2026 14:45:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 11/02/2026 23:30:00. 50 Economy ticket for £101 per person are available. Travel duration is 8h 45m
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Wizz Air17h 25m019:15Prague AirportPrague Airport12:40Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 11/02/2026 19:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/02/2026 12:40:00. 50 Economy ticket for £128 per person are available. Travel duration is 17h 25m
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Vueling Airlines20h 50m021:10Prague AirportPrague Airport18:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 11/02/2026 21:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/02/2026 18:00:00. 50 Economy ticket for £140 per person are available. Travel duration is 20h 50m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
What are the fastest trips from Prague to Rome?
You can get to Rome from Prague in just 1h 50m with a Flight from Skyscanner. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Skyscanner1h 50m019:10Prague AirportPrague Airport - T1/221:00Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 19:10:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 05/02/2026 21:00:00. 50 Economy ticket for £59 per person are available. Travel duration is 1h 50m
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Buzz4h 40m016:15Prague AirportPrague Airport - T1/220:55Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 16:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 05/02/2026 20:55:00. 50 Economy ticket for £82 per person are available. Travel duration is 4h 40m
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Air Bagan6h 25m018:50Prague AirportPrague Airport - T1/201:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 18:50:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 06/02/2026 01:15:00. 50 Economy ticket for £108 per person are available. Travel duration is 6h 25m
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Astra Airlines9h 20m012:15Prague AirportPrague Airport - T1/221:35Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Astra Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 12:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 05/02/2026 21:35:00. 50 Economy ticket for £79 per person are available. Travel duration is 9h 20m
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Fly One16h 0m019:00Prague AirportPrague Airport11:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Fly One goes from Prague Airport, Prague Airport (Czech Republic) at 05/02/2026 19:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 06/02/2026 11:00:00. 50 Economy ticket for £117 per person are available. Travel duration is 16h 0m
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Norwegian Air International23h 5m013:45Prague AirportPrague Airport - T1/212:50Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Norwegian Air International goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 13:45:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 06/02/2026 12:50:00. 50 Economy ticket for £111 per person are available. Travel duration is 23h 5m
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FlixBus20h 25m013:05PragueWilsonova Coach Station09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 05/02/2026 13:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/02/2026 09:30:00. 50 Economy ticket for £78 per person are available. Travel duration is 20h 25m
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FlixBus20h 40m012:50PragueÚAN Florenc09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 05/02/2026 12:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/02/2026 09:30:00. 50 Economy ticket for £78 per person are available. Travel duration is 20h 40m
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FlixBus22h 50m014:30PragueČerný Most13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 05/02/2026 14:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/02/2026 13:20:00. 50 Economy ticket for £78 per person are available. Travel duration is 22h 50m
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FlixBus23h 25m023:35PragueÚAN Florenc23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 05/02/2026 23:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/02/2026 23:00:00. 50 Economy ticket for £79 per person are available. Travel duration is 23h 25m
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FlixBus24h 15m022:45Prague AirportPrague Airport - T1/223:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 05/02/2026 22:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 06/02/2026 23:00:00. 50 Economy ticket for £67 per person are available. Travel duration is 24h 15m
Fastest Flights Thursday
Fastest Buses Thursday
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 06/02/2026 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 07/02/2026 18:00:00. 50 Economy ticket for £60 per person are available. Travel duration is 23h 10m
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FlixBus23h 10m023:50PragueWilsonova Coach Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 06/02/2026 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 07/02/2026 23:00:00. 50 Economy ticket for £68 per person are available. Travel duration is 23h 10m
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FlixBus23h 50m018:55PragueZličín18:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 06/02/2026 18:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 07/02/2026 18:45:00. 50 Economy ticket for £68 per person are available. Travel duration is 23h 50m
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FlixBus24h 15m022:45Prague AirportPrague Airport - T1/223:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 06/02/2026 22:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 07/02/2026 23:00:00. 50 Economy ticket for £66 per person are available. Travel duration is 24h 15m
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FlixBus27h 45m011:20Prague AirportPrague Airport - T1/215:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 06/02/2026 11:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 07/02/2026 15:05:00. 50 Economy ticket for £66 per person are available. Travel duration is 27h 45m
Fastest Buses Friday
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Lufthansa4h 45m006:15Prague AirportPrague Airport11:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Lufthansa goes from Prague Airport, Prague Airport (Czech Republic) at 07/02/2026 06:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 07/02/2026 11:00:00. 50 Economy ticket for £151 per person are available. Travel duration is 4h 45m
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EasyJet Airline7h 40m009:00Prague AirportPrague Airport16:40Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 07/02/2026 09:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 07/02/2026 16:40:00. 50 Economy ticket for £131 per person are available. Travel duration is 7h 40m
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Iberia10h 30m021:10Prague AirportPrague Airport07:40Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Iberia goes from Prague Airport, Prague Airport (Czech Republic) at 07/02/2026 21:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 08/02/2026 07:40:00. 50 Economy ticket for £139 per person are available. Travel duration is 10h 30m
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Vueling Airlines13h 55m021:10Prague AirportPrague Airport11:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 07/02/2026 21:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 08/02/2026 11:05:00. 50 Economy ticket for £95 per person are available. Travel duration is 13h 55m
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Smartwings16h 20m006:40Prague AirportPrague Airport23:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 07/02/2026 06:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 07/02/2026 23:00:00. 50 Economy ticket for £100 per person are available. Travel duration is 16h 20m
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FlixBus19h 35m017:45PragueNa Knížecí Station13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 07/02/2026 17:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 08/02/2026 13:20:00. 50 Economy ticket for £60 per person are available. Travel duration is 19h 35m
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FlixBus20h 0m021:25PragueÚAN Florenc17:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 07/02/2026 21:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 08/02/2026 17:25:00. 50 Economy ticket for £60 per person are available. Travel duration is 20h 0m
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FlixBus20h 35m021:25PragueÚAN Florenc18:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 07/02/2026 21:25:00 to Anagnina Bus Station, Rome (Italy) arriving at 08/02/2026 18:00:00. 50 Economy ticket for £60 per person are available. Travel duration is 20h 35m
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FlixBus21h 20m017:45PragueNa Knížecí Station15:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 07/02/2026 17:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 08/02/2026 15:05:00. 50 Economy ticket for £59 per person are available. Travel duration is 21h 20m
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 07/02/2026 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 08/02/2026 18:00:00. 50 Economy ticket for £58 per person are available. Travel duration is 23h 10m
Fastest Flights Saturday
Fastest Buses Saturday
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Buzz1h 50m006:20Prague AirportPrague Airport - T1/208:10Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 06:20:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 08/02/2026 08:10:00. 50 Economy ticket for £98 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m018:40Prague AirportPrague Airport - T1/220:30Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 18:40:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 08/02/2026 20:30:00. 50 Economy ticket for £128 per person are available. Travel duration is 1h 50m
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Smartwings1h 55m011:20Prague AirportPrague Airport - T1/213:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 11:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 08/02/2026 13:15:00. 50 Economy ticket for £64 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m022:55Prague AirportPrague Airport - T1/200:50Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 22:55:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 09/02/2026 00:50:00. 50 Economy ticket for £100 per person are available. Travel duration is 1h 55m
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Air Serbia11h 45m020:30Prague AirportPrague Airport08:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Serbia goes from Prague Airport, Prague Airport (Czech Republic) at 08/02/2026 20:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 09/02/2026 08:15:00. 50 Economy ticket for £99 per person are available. Travel duration is 11h 45m
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Buzz14h 15m017:10Prague AirportPrague Airport - T1/207:25Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 17:10:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 09/02/2026 07:25:00. 50 Economy ticket for £74 per person are available. Travel duration is 14h 15m
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FlixBus20h 35m021:25PragueÚAN Florenc18:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 08/02/2026 21:25:00 to Anagnina Bus Station, Rome (Italy) arriving at 09/02/2026 18:00:00. 50 Economy ticket for £58 per person are available. Travel duration is 20h 35m
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FlixBus21h 35m017:30PragueWilsonova Coach Station15:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 08/02/2026 17:30:00 to Anagnina Bus Station, Rome (Italy) arriving at 09/02/2026 15:05:00. 50 Economy ticket for £57 per person are available. Travel duration is 21h 35m
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FlixBus21h 50m017:15PragueÚAN Florenc15:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 08/02/2026 17:15:00 to Anagnina Bus Station, Rome (Italy) arriving at 09/02/2026 15:05:00. 50 Economy ticket for £57 per person are available. Travel duration is 21h 50m
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FlixBus22h 35m018:50Prague AirportPrague Airport - T1/217:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 18:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 09/02/2026 17:25:00. 50 Economy ticket for £55 per person are available. Travel duration is 22h 35m
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 08/02/2026 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 09/02/2026 18:00:00. 50 Economy ticket for £55 per person are available. Travel duration is 23h 10m
Fastest Flights Sunday
Fastest Buses Sunday
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FlixBus20h 0m021:25PragueÚAN Florenc17:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 09/02/2026 21:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 10/02/2026 17:25:00. 50 Economy ticket for £52 per person are available. Travel duration is 20h 0m
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FlixBus20h 25m013:05PragueWilsonova Coach Station09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 09/02/2026 13:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 10/02/2026 09:30:00. 50 Economy ticket for £55 per person are available. Travel duration is 20h 25m
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FlixBus20h 35m021:25PragueÚAN Florenc18:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 09/02/2026 21:25:00 to Anagnina Bus Station, Rome (Italy) arriving at 10/02/2026 18:00:00. 50 Economy ticket for £53 per person are available. Travel duration is 20h 35m
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FlixBus22h 35m018:50Prague AirportPrague Airport - T1/217:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 09/02/2026 18:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 10/02/2026 17:25:00. 50 Economy ticket for £52 per person are available. Travel duration is 22h 35m
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 09/02/2026 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 10/02/2026 18:00:00. 50 Economy ticket for £52 per person are available. Travel duration is 23h 10m
Fastest Buses Monday
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Skyscanner1h 50m008:30Prague AirportPrague Airport - T1/210:20Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 08:30:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 10/02/2026 10:20:00. 50 Economy ticket for £40 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m014:35Prague AirportPrague Airport - T1/216:25Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 14:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 10/02/2026 16:25:00. 50 Economy ticket for £51 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m009:25Prague AirportPrague Airport - T1/211:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 10/02/2026 11:20:00. 50 Economy ticket for £52 per person are available. Travel duration is 1h 55m
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Ryanair8h 55m011:35Prague AirportPrague Airport - T1/220:30Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 11:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 10/02/2026 20:30:00. 50 Economy ticket for £70 per person are available. Travel duration is 8h 55m
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Air Malta11h 5m020:40Prague AirportPrague Airport - T1/207:45Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 20:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 11/02/2026 07:45:00. 50 Economy ticket for £87 per person are available. Travel duration is 11h 5m
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EasyJet Airline16h 0m020:50Prague AirportPrague Airport12:50Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 10/02/2026 20:50:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 11/02/2026 12:50:00. 50 Economy ticket for £113 per person are available. Travel duration is 16h 0m
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FlixBus22h 35m018:50Prague AirportPrague Airport - T1/217:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 18:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 11/02/2026 17:25:00. 50 Economy ticket for £56 per person are available. Travel duration is 22h 35m
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FlixBus23h 15m018:50Prague AirportPrague Airport - T1/218:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 11/02/2026 18:05:00. 50 Economy ticket for £51 per person are available. Travel duration is 23h 15m
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FlixBus23h 20m019:25PragueZličín18:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 10/02/2026 19:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 11/02/2026 18:45:00. 50 Economy ticket for £56 per person are available. Travel duration is 23h 20m
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FlixBus24h 40m008:50Prague AirportPrague Airport - T1/209:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 08:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 11/02/2026 09:30:00. 50 Economy ticket for £47 per person are available. Travel duration is 24h 40m
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FlixBus26h 0m011:20Prague AirportPrague Airport - T1/213:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 10/02/2026 11:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 11/02/2026 13:20:00. 50 Economy ticket for £56 per person are available. Travel duration is 26h 0m
Fastest Flights Tuesday
Fastest Buses Tuesday
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EasyJet Airline8h 45m014:45Prague AirportPrague Airport23:30Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 11/02/2026 14:45:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 11/02/2026 23:30:00. 50 Economy ticket for £101 per person are available. Travel duration is 8h 45m
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Iberia11h 45m012:30Prague AirportPrague Airport00:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Iberia goes from Prague Airport, Prague Airport (Czech Republic) at 11/02/2026 12:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/02/2026 00:15:00. 50 Economy ticket for £91 per person are available. Travel duration is 11h 45m
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Air Serbia11h 45m020:30Prague AirportPrague Airport08:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Serbia goes from Prague Airport, Prague Airport (Czech Republic) at 11/02/2026 20:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/02/2026 08:15:00. 50 Economy ticket for £99 per person are available. Travel duration is 11h 45m
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Wizz Air17h 25m019:15Prague AirportPrague Airport12:40Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 11/02/2026 19:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/02/2026 12:40:00. 50 Economy ticket for £128 per person are available. Travel duration is 17h 25m
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Vueling Airlines20h 50m021:10Prague AirportPrague Airport18:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 11/02/2026 21:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 12/02/2026 18:00:00. 50 Economy ticket for £140 per person are available. Travel duration is 20h 50m
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FlixBus23h 50m009:40PragueNa Knížecí Station09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 11/02/2026 09:40:00 to Tiburtina Bus Station, Rome (Italy) arriving at 12/02/2026 09:30:00. 50 Economy ticket for £52 per person are available. Travel duration is 23h 50m
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FlixBus24h 20m017:45PragueNa Knížecí Station18:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 11/02/2026 17:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 12/02/2026 18:05:00. 50 Economy ticket for £52 per person are available. Travel duration is 24h 20m
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FlixBus24h 40m008:50Prague AirportPrague Airport - T1/209:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 11/02/2026 08:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 12/02/2026 09:30:00. 50 Economy ticket for £49 per person are available. Travel duration is 24h 40m
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FlixBus27h 35m014:30PragueČerný Most18:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 11/02/2026 14:30:00 to Anagnina Bus Station, Rome (Italy) arriving at 12/02/2026 18:05:00. 50 Economy ticket for £53 per person are available. Travel duration is 27h 35m
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FlixBus27h 40m005:50PragueWilsonova Coach Station09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 11/02/2026 05:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 12/02/2026 09:30:00. 50 Economy ticket for £52 per person are available. Travel duration is 27h 40m
Fastest Flights Wednesday
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Prague to Rome
What are the most popular stations in Prague and Rome?
In Prague, you will usually depart from Wilsonova Coach Station, ÚAN Florenc or Černý Most, while in Rome you will be arriving at Termini Bus Station, Termini Central Station or Ostiense Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Rome from Prague? With 9 connections between 1 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Rome, you can pay as low as £40 with a Flight from Skyscanner.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Rome in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Rome are FlixBus, Buzz and Skyscanner, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Prague and Rome is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Settebagni, and look at flights from Prague Airport, and landing at Rome Ciampino Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Prague to Rome?
The most popular companies between Prague and Rome, are FlixBus, Buzz and Skyscanner. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: Buzz, Skyscanner, EasyJet Airline and 15 more.
All you need to know when you travel from Prague to Rome
Check all information on comfort and services on all modes of transports from Prague to Rome. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Prague to Rome
How can I reach Rome from Prague?
Every day, there are on average 9 connections between Flight and Bus, with which you can get to Rome from Prague.
How far is Rome from Prague?
The distance between Prague and Rome is 921.0 km.
What is the most ecofriendly mode of transport between Prague and Rome?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 157 kgs, and a flight 227 kgs.
What is the cheapest mode of transport from Prague to Rome?
You can get to Rome with just £40 by taking a Flight from Skyscanner.
What is the fastest way to get from Prague to Rome?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Rome in just 1h 50m with a Flight from Skyscanner.
More routes to Prague and to Rome
Looking for more options? Here you can see the most popular routes to Prague and to Rome. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Bratislava to Prague
- Brno to Prague
- Budapest to Prague
- Cheb to Prague
- Dresden to Prague
- Florence to Prague
- Karlovy Vary to Prague
- Katowice to Prague
- Krakow to Prague
- Leipzig to Prague
- Linz to Prague
- London to Prague
- Lyon to Prague
- Milan to Prague
- Minsk to Prague
- Munich to Prague
- Nuremberg to Prague
- Regensburg to Prague
- Třebíč to Prague
- Venice to Prague
- Vienna to Prague
- Zurich to Prague
- Trips to Rome
- Bari to Rome
- Basel to Rome
- Benevento to Rome
- Brindisi to Rome
- Chieti to Rome
- Civitavecchia to Rome
- Fisciano to Rome
- Florence to Rome
- Foggia to Rome
- Grottammare to Rome
- Lamezia Terme to Rome
- Lauria to Rome
- Matera to Rome
- Mosciano Sant'Angelo to Rome
- Nocera Inferiore to Rome
- Perugia to Rome
- Pescara to Rome
- Rome Fiumicino Airport to Rome
- San Benedetto del Tronto to Rome
- Siena to Rome
- Teramo to Rome
- Trapani to Rome
- Trebisacce to Rome
- Venice to Rome
