What is the best way to travel from Prague to Rome?
Looking for a trip? Check and compare all the available Flights and Buses to Rome from Prague. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Rome from Prague?
You can reach Rome with just £37 by taking a Flight from LC Perú, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Skyscanner1h 50m008:15Prague AirportPrague Airport - T1/210:05Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/03/2026 08:15:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/03/2026 10:05:00. 50 Economy ticket for £49 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m009:25Prague AirportPrague Airport - T1/211:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/03/2026 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/03/2026 11:20:00. 50 Economy ticket for £56 per person are available. Travel duration is 1h 55m
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Air Bagan6h 15m019:00Prague AirportPrague Airport - T1/201:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/03/2026 19:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 24/03/2026 01:15:00. 50 Economy ticket for £66 per person are available. Travel duration is 6h 15m
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Jet2.com24h 50m019:40Prague AirportPrague Airport - T1/220:30Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Jet2.com goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/03/2026 19:40:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 24/03/2026 20:30:00. 50 Economy ticket for £67 per person are available. Travel duration is 24h 50m
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Ryanair6h 25m014:45Prague AirportPrague Airport - T1/221:10Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/03/2026 14:45:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/03/2026 21:10:00. 50 Economy ticket for £69 per person are available. Travel duration is 6h 25m
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Air Bagan15h 5m019:00Prague AirportPrague Airport - T1/210:05Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/03/2026 19:00:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 24/03/2026 10:05:00. 50 Economy ticket for £69 per person are available. Travel duration is 15h 5m
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/03/2026 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 24/03/2026 18:00:00. 50 Economy ticket for £60 per person are available. Travel duration is 23h 10m
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FlixBus22h 35m018:50Prague AirportPrague Airport - T1/217:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/03/2026 18:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 17:25:00. 50 Economy ticket for £60 per person are available. Travel duration is 22h 35m
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FlixBus23h 20m019:25PragueZličín18:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 23/03/2026 19:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 18:45:00. 50 Economy ticket for £72 per person are available. Travel duration is 23h 20m
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FlixBus25h 35m017:10PragueRoztyly18:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 23/03/2026 17:10:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 18:45:00. 50 Economy ticket for £73 per person are available. Travel duration is 25h 35m
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FlixBus20h 35m021:25PragueÚAN Florenc18:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 23/03/2026 21:25:00 to Anagnina Bus Station, Rome (Italy) arriving at 24/03/2026 18:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 20h 35m
Cheapest Flights Monday
Cheapest Buses Monday
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FlixBus23h 20m019:25PragueZličín18:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 24/03/2026 19:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 18:45:00. 50 Economy ticket for £62 per person are available. Travel duration is 23h 20m
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FlixBus24h 20m017:45PragueNa Knížecí Station18:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 24/03/2026 17:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 25/03/2026 18:05:00. 50 Economy ticket for £63 per person are available. Travel duration is 24h 20m
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FlixBus24h 40m008:50Prague AirportPrague Airport - T1/209:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 24/03/2026 08:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 09:30:00. 50 Economy ticket for £66 per person are available. Travel duration is 24h 40m
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FlixBus24h 0m013:20Prague AirportPrague Airport - T1/213:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 24/03/2026 13:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 13:20:00. 50 Economy ticket for £66 per person are available. Travel duration is 24h 0m
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FlixBus19h 35m017:45PragueNa Knížecí Station13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 24/03/2026 17:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 13:20:00. 50 Economy ticket for £67 per person are available. Travel duration is 19h 35m
Cheapest Buses Tuesday
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FlixBus23h 20m019:25PragueZličín18:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 25/03/2026 19:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 18:45:00. 50 Economy ticket for £78 per person are available. Travel duration is 23h 20m
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FlixBus28h 45m013:20Prague AirportPrague Airport - T1/218:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/03/2026 13:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 26/03/2026 18:05:00. 50 Economy ticket for £85 per person are available. Travel duration is 28h 45m
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FlixBus20h 45m017:20PragueÚAN Florenc14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 25/03/2026 17:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 14:05:00. 50 Economy ticket for £86 per person are available. Travel duration is 20h 45m
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FlixBus20h 30m017:35PragueWilsonova Coach Station14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 25/03/2026 17:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 14:05:00. 50 Economy ticket for £86 per person are available. Travel duration is 20h 30m
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FlixBus24h 0m013:20Prague AirportPrague Airport - T1/213:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/03/2026 13:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 13:20:00. 50 Economy ticket for £88 per person are available. Travel duration is 24h 0m
Cheapest Buses Wednesday
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LC Perú1h 55m021:10Prague AirportPrague Airport - T1/223:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/03/2026 21:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/03/2026 23:05:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 55m
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Ryanair1h 50m019:10Prague AirportPrague Airport - T1/221:00Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/03/2026 19:10:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 26/03/2026 21:00:00. 50 Economy ticket for £48 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m019:10Prague AirportPrague Airport - T1/221:00Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/03/2026 19:10:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 26/03/2026 21:00:00. 50 Economy ticket for £54 per person are available. Travel duration is 1h 50m
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Smartwings11h 0m006:40Prague AirportPrague Airport - T1/217:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/03/2026 06:40:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 26/03/2026 17:40:00. 50 Economy ticket for £94 per person are available. Travel duration is 11h 0m
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Buzz4h 50m016:05Prague AirportPrague Airport - T1/220:55Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/03/2026 16:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/03/2026 20:55:00. 50 Economy ticket for £96 per person are available. Travel duration is 4h 50m
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Smartwings1h 55m011:20Prague AirportPrague Airport - T1/213:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/03/2026 11:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/03/2026 13:15:00. 50 Economy ticket for £98 per person are available. Travel duration is 1h 55m
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FlixBus26h 35m009:40PragueNa Knížecí Station12:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 26/03/2026 09:40:00 to Anagnina Bus Station, Rome (Italy) arriving at 27/03/2026 12:15:00. 50 Economy ticket for £79 per person are available. Travel duration is 26h 35m
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FlixBus23h 10m023:50PragueWilsonova Coach Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 26/03/2026 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 23:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 23h 10m
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FlixBus23h 20m023:40PragueÚAN Florenc23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 26/03/2026 23:40:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 23:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 23h 20m
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FlixBus28h 15m023:45PragueÚAN Florenc04:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 26/03/2026 23:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 28/03/2026 04:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 28h 15m
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FlixBus28h 40m013:20Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/03/2026 13:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 27/03/2026 18:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 28h 40m
Cheapest Flights Thursday
Cheapest Buses Thursday
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Wizz Air1h 55m009:25Prague AirportPrague Airport - T1/211:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/03/2026 11:20:00. 50 Economy ticket for £57 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m009:25Prague AirportPrague Airport - T1/211:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/03/2026 11:20:00. 50 Economy ticket for £63 per person are available. Travel duration is 1h 55m
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LC Perú23h 10m022:35Prague AirportPrague Airport - T1/221:45Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 22:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 28/03/2026 21:45:00. 50 Economy ticket for £70 per person are available. Travel duration is 23h 10m
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Skyscanner1h 50m019:50Prague AirportPrague Airport - T1/221:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 19:50:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 27/03/2026 21:40:00. 50 Economy ticket for £71 per person are available. Travel duration is 1h 50m
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Buzz14h 25m006:30Prague AirportPrague Airport - T1/220:55Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 06:30:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 27/03/2026 20:55:00. 50 Economy ticket for £75 per person are available. Travel duration is 14h 25m
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Ryanair1h 50m019:50Prague AirportPrague Airport - T1/221:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 19:50:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 27/03/2026 21:40:00. 50 Economy ticket for £75 per person are available. Travel duration is 1h 50m
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FlixBus28h 15m023:45PragueÚAN Florenc05:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 27/03/2026 23:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 29/03/2026 05:00:00. 50 Economy ticket for £75 per person are available. Travel duration is 28h 15m
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FlixBus20h 30m002:30PragueWilsonova Coach Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 27/03/2026 02:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 23:00:00. 50 Economy ticket for £86 per person are available. Travel duration is 20h 30m
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FlixBus27h 0m006:20PragueČerný Most09:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 27/03/2026 06:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 28/03/2026 09:20:00. 50 Economy ticket for £96 per person are available. Travel duration is 27h 0m
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FlixBus22h 35m018:50Prague AirportPrague Airport - T1/217:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 18:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 28/03/2026 17:25:00. 50 Economy ticket for £96 per person are available. Travel duration is 22h 35m
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FlixBus31h 20m022:45Prague AirportPrague Airport - T1/207:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 22:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 29/03/2026 07:05:00. 50 Economy ticket for £96 per person are available. Travel duration is 31h 20m
Cheapest Flights Friday
Cheapest Buses Friday
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FlixBus27h 0m006:20PragueČerný Most10:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 28/03/2026 06:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 29/03/2026 10:20:00. 50 Economy ticket for £68 per person are available. Travel duration is 27h 0m
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FlixBus27h 15m023:45PragueÚAN Florenc04:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 28/03/2026 23:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 30/03/2026 04:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 27h 15m
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FlixBus22h 15m018:50Prague AirportPrague Airport - T1/218:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 28/03/2026 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 29/03/2026 18:05:00. 50 Economy ticket for £83 per person are available. Travel duration is 22h 15m
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FlixBus19h 40m021:25PragueÚAN Florenc18:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 28/03/2026 21:25:00 to Anagnina Bus Station, Rome (Italy) arriving at 29/03/2026 18:05:00. 50 Economy ticket for £87 per person are available. Travel duration is 19h 40m
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FlixBus22h 55m018:50Prague AirportPrague Airport - T1/218:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 28/03/2026 18:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 29/03/2026 18:45:00. 50 Economy ticket for £88 per person are available. Travel duration is 22h 55m
Cheapest Buses Saturday
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LC Perú27h 5m018:05Prague AirportPrague Airport - T1/221:10Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 29/03/2026 18:05:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 30/03/2026 21:10:00. 50 Economy ticket for £56 per person are available. Travel duration is 27h 5m
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LC Perú2h 0m009:25Prague AirportPrague Airport - T1/211:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 29/03/2026 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 29/03/2026 11:25:00. 50 Economy ticket for £64 per person are available. Travel duration is 2h 0m
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Wizz Air2h 0m009:25Prague AirportPrague Airport - T1/211:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 29/03/2026 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 29/03/2026 11:25:00. 50 Economy ticket for £64 per person are available. Travel duration is 2h 0m
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Skyscanner1h 50m013:50Prague AirportPrague Airport - T1/215:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 29/03/2026 13:50:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 29/03/2026 15:40:00. 50 Economy ticket for £80 per person are available. Travel duration is 1h 50m
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Buzz13h 55m007:10Prague AirportPrague Airport - T1/221:05Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 29/03/2026 07:10:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 29/03/2026 21:05:00. 50 Economy ticket for £88 per person are available. Travel duration is 13h 55m
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Ryanair1h 50m013:50Prague AirportPrague Airport - T1/215:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 29/03/2026 13:50:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 29/03/2026 15:40:00. 50 Economy ticket for £88 per person are available. Travel duration is 1h 50m
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FlixBus27h 0m006:20PragueČerný Most09:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 29/03/2026 06:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 30/03/2026 09:20:00. 50 Economy ticket for £70 per person are available. Travel duration is 27h 0m
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FlixBus23h 10m023:50PragueWilsonova Coach Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 29/03/2026 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 30/03/2026 23:00:00. 50 Economy ticket for £77 per person are available. Travel duration is 23h 10m
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FlixBus25h 10m021:50PragueNa Knížecí Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 29/03/2026 21:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 30/03/2026 23:00:00. 50 Economy ticket for £77 per person are available. Travel duration is 25h 10m
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FlixBus23h 20m023:40PragueÚAN Florenc23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 29/03/2026 23:40:00 to Tiburtina Bus Station, Rome (Italy) arriving at 30/03/2026 23:00:00. 50 Economy ticket for £77 per person are available. Travel duration is 23h 20m
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FlixBus24h 35m022:25PragueHradčanská23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 29/03/2026 22:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 30/03/2026 23:00:00. 50 Economy ticket for £77 per person are available. Travel duration is 24h 35m
Cheapest Flights Sunday
Cheapest Buses Sunday
What are the fastest trips from Prague to Rome?
You can get to Rome from Prague in just 1h 50m with a Flight from Ryanair. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Skyscanner1h 50m008:15Prague AirportPrague Airport - T1/210:05Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/03/2026 08:15:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/03/2026 10:05:00. 50 Economy ticket for £49 per person are available. Travel duration is 1h 50m
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Buzz1h 50m017:50Prague AirportPrague Airport - T1/219:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/03/2026 17:50:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/03/2026 19:40:00. 50 Economy ticket for £78 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m009:25Prague AirportPrague Airport - T1/211:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/03/2026 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/03/2026 11:20:00. 50 Economy ticket for £56 per person are available. Travel duration is 1h 55m
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Smartwings1h 55m011:20Prague AirportPrague Airport13:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 23/03/2026 11:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/03/2026 13:15:00. 50 Economy ticket for £69 per person are available. Travel duration is 1h 55m
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Air Bagan6h 15m019:00Prague AirportPrague Airport - T1/201:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/03/2026 19:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 24/03/2026 01:15:00. 50 Economy ticket for £66 per person are available. Travel duration is 6h 15m
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Ryanair6h 25m014:45Prague AirportPrague Airport - T1/221:10Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/03/2026 14:45:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/03/2026 21:10:00. 50 Economy ticket for £69 per person are available. Travel duration is 6h 25m
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FlixBus20h 35m021:25PragueÚAN Florenc18:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 23/03/2026 21:25:00 to Anagnina Bus Station, Rome (Italy) arriving at 24/03/2026 18:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 20h 35m
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FlixBus22h 35m018:50Prague AirportPrague Airport - T1/217:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/03/2026 18:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 17:25:00. 50 Economy ticket for £60 per person are available. Travel duration is 22h 35m
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/03/2026 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 24/03/2026 18:00:00. 50 Economy ticket for £60 per person are available. Travel duration is 23h 10m
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FlixBus23h 20m019:25PragueZličín18:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 23/03/2026 19:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 18:45:00. 50 Economy ticket for £72 per person are available. Travel duration is 23h 20m
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FlixBus25h 35m017:10PragueRoztyly18:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 23/03/2026 17:10:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 18:45:00. 50 Economy ticket for £73 per person are available. Travel duration is 25h 35m
Fastest Flights Monday
Fastest Buses Monday
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FlixBus19h 35m017:45PragueNa Knížecí Station13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 24/03/2026 17:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 13:20:00. 50 Economy ticket for £67 per person are available. Travel duration is 19h 35m
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FlixBus23h 20m019:25PragueZličín18:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 24/03/2026 19:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 18:45:00. 50 Economy ticket for £62 per person are available. Travel duration is 23h 20m
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FlixBus24h 0m013:20Prague AirportPrague Airport - T1/213:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 24/03/2026 13:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 13:20:00. 50 Economy ticket for £66 per person are available. Travel duration is 24h 0m
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FlixBus24h 20m017:45PragueNa Knížecí Station18:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 24/03/2026 17:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 25/03/2026 18:05:00. 50 Economy ticket for £63 per person are available. Travel duration is 24h 20m
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FlixBus24h 40m008:50Prague AirportPrague Airport - T1/209:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 24/03/2026 08:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 09:30:00. 50 Economy ticket for £66 per person are available. Travel duration is 24h 40m
Fastest Buses Tuesday
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FlixBus20h 30m017:35PragueWilsonova Coach Station14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 25/03/2026 17:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 14:05:00. 50 Economy ticket for £86 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m017:20PragueÚAN Florenc14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 25/03/2026 17:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 14:05:00. 50 Economy ticket for £86 per person are available. Travel duration is 20h 45m
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FlixBus23h 20m019:25PragueZličín18:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 25/03/2026 19:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 18:45:00. 50 Economy ticket for £78 per person are available. Travel duration is 23h 20m
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FlixBus24h 0m013:20Prague AirportPrague Airport - T1/213:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/03/2026 13:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 13:20:00. 50 Economy ticket for £88 per person are available. Travel duration is 24h 0m
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FlixBus28h 45m013:20Prague AirportPrague Airport - T1/218:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/03/2026 13:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 26/03/2026 18:05:00. 50 Economy ticket for £85 per person are available. Travel duration is 28h 45m
Fastest Buses Wednesday
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Ryanair1h 50m019:10Prague AirportPrague Airport - T1/221:00Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/03/2026 19:10:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 26/03/2026 21:00:00. 50 Economy ticket for £48 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m019:10Prague AirportPrague Airport - T1/221:00Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/03/2026 19:10:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 26/03/2026 21:00:00. 50 Economy ticket for £54 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m021:10Prague AirportPrague Airport - T1/223:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/03/2026 21:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/03/2026 23:05:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 55m
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Smartwings1h 55m011:20Prague AirportPrague Airport - T1/213:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/03/2026 11:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/03/2026 13:15:00. 50 Economy ticket for £98 per person are available. Travel duration is 1h 55m
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Buzz4h 50m016:05Prague AirportPrague Airport - T1/220:55Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/03/2026 16:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/03/2026 20:55:00. 50 Economy ticket for £96 per person are available. Travel duration is 4h 50m
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EasyJet Airline6h 5m009:00Prague AirportPrague Airport - T1/215:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/03/2026 09:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/03/2026 15:05:00. 50 Economy ticket for £98 per person are available. Travel duration is 6h 5m
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FlixBus23h 10m023:50PragueWilsonova Coach Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 26/03/2026 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 23:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 23h 10m
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FlixBus23h 20m023:40PragueÚAN Florenc23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 26/03/2026 23:40:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 23:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 23h 20m
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FlixBus26h 35m009:40PragueNa Knížecí Station12:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 26/03/2026 09:40:00 to Anagnina Bus Station, Rome (Italy) arriving at 27/03/2026 12:15:00. 50 Economy ticket for £79 per person are available. Travel duration is 26h 35m
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FlixBus28h 15m023:45PragueÚAN Florenc04:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 26/03/2026 23:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 28/03/2026 04:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 28h 15m
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FlixBus28h 40m013:20Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/03/2026 13:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 27/03/2026 18:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 28h 40m
Fastest Flights Thursday
Fastest Buses Thursday
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Skyscanner1h 50m019:50Prague AirportPrague Airport - T1/221:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 19:50:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 27/03/2026 21:40:00. 50 Economy ticket for £71 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m019:50Prague AirportPrague Airport - T1/221:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 19:50:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 27/03/2026 21:40:00. 50 Economy ticket for £75 per person are available. Travel duration is 1h 50m
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Wizz Air1h 55m009:25Prague AirportPrague Airport - T1/211:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/03/2026 11:20:00. 50 Economy ticket for £57 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m009:25Prague AirportPrague Airport - T1/211:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/03/2026 11:20:00. 50 Economy ticket for £63 per person are available. Travel duration is 1h 55m
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Volotea4h 15m008:20Prague AirportPrague Airport - T1/212:35Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 08:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/03/2026 12:35:00. 50 Economy ticket for £109 per person are available. Travel duration is 4h 15m
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TAROM5h 55m009:30Prague AirportPrague Airport - T1/215:25Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from TAROM goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 09:30:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 27/03/2026 15:25:00. 50 Economy ticket for £151 per person are available. Travel duration is 5h 55m
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FlixBus20h 30m002:30PragueWilsonova Coach Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 27/03/2026 02:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 23:00:00. 50 Economy ticket for £86 per person are available. Travel duration is 20h 30m
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FlixBus22h 35m018:50Prague AirportPrague Airport - T1/217:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 18:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 28/03/2026 17:25:00. 50 Economy ticket for £96 per person are available. Travel duration is 22h 35m
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FlixBus27h 0m006:20PragueČerný Most09:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 27/03/2026 06:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 28/03/2026 09:20:00. 50 Economy ticket for £96 per person are available. Travel duration is 27h 0m
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FlixBus28h 15m023:45PragueÚAN Florenc05:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 27/03/2026 23:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 29/03/2026 05:00:00. 50 Economy ticket for £75 per person are available. Travel duration is 28h 15m
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FlixBus31h 20m022:45Prague AirportPrague Airport - T1/207:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 27/03/2026 22:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 29/03/2026 07:05:00. 50 Economy ticket for £96 per person are available. Travel duration is 31h 20m
Fastest Flights Friday
Fastest Buses Friday
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FlixBus19h 40m021:25PragueÚAN Florenc18:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 28/03/2026 21:25:00 to Anagnina Bus Station, Rome (Italy) arriving at 29/03/2026 18:05:00. 50 Economy ticket for £87 per person are available. Travel duration is 19h 40m
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FlixBus22h 15m018:50Prague AirportPrague Airport - T1/218:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 28/03/2026 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 29/03/2026 18:05:00. 50 Economy ticket for £83 per person are available. Travel duration is 22h 15m
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FlixBus22h 55m018:50Prague AirportPrague Airport - T1/218:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 28/03/2026 18:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 29/03/2026 18:45:00. 50 Economy ticket for £88 per person are available. Travel duration is 22h 55m
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FlixBus27h 0m006:20PragueČerný Most10:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 28/03/2026 06:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 29/03/2026 10:20:00. 50 Economy ticket for £68 per person are available. Travel duration is 27h 0m
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FlixBus27h 15m023:45PragueÚAN Florenc04:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 28/03/2026 23:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 30/03/2026 04:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 27h 15m
Fastest Buses Saturday
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Skyscanner1h 50m013:50Prague AirportPrague Airport - T1/215:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 29/03/2026 13:50:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 29/03/2026 15:40:00. 50 Economy ticket for £80 per person are available. Travel duration is 1h 50m
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Ryanair1h 50m013:50Prague AirportPrague Airport - T1/215:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Ryanair goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 29/03/2026 13:50:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 29/03/2026 15:40:00. 50 Economy ticket for £88 per person are available. Travel duration is 1h 50m
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Smartwings1h 55m011:20Prague AirportPrague Airport13:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 29/03/2026 11:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 29/03/2026 13:15:00. 50 Economy ticket for £91 per person are available. Travel duration is 1h 55m
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LC Perú2h 0m009:25Prague AirportPrague Airport - T1/211:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 29/03/2026 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 29/03/2026 11:25:00. 50 Economy ticket for £64 per person are available. Travel duration is 2h 0m
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Wizz Air2h 0m009:25Prague AirportPrague Airport - T1/211:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 29/03/2026 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 29/03/2026 11:25:00. 50 Economy ticket for £64 per person are available. Travel duration is 2h 0m
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Brussels Airlines12h 5m021:15Prague AirportPrague Airport - T1/209:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Brussels Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 29/03/2026 21:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 30/03/2026 09:20:00. 50 Economy ticket for £117 per person are available. Travel duration is 12h 5m
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FlixBus23h 10m023:50PragueWilsonova Coach Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 29/03/2026 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 30/03/2026 23:00:00. 50 Economy ticket for £77 per person are available. Travel duration is 23h 10m
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FlixBus23h 20m023:40PragueÚAN Florenc23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 29/03/2026 23:40:00 to Tiburtina Bus Station, Rome (Italy) arriving at 30/03/2026 23:00:00. 50 Economy ticket for £77 per person are available. Travel duration is 23h 20m
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FlixBus24h 35m022:25PragueHradčanská23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Hradčanská, Prague (Czech Republic) at 29/03/2026 22:25:00 to Tiburtina Bus Station, Rome (Italy) arriving at 30/03/2026 23:00:00. 50 Economy ticket for £77 per person are available. Travel duration is 24h 35m
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FlixBus25h 10m021:50PragueNa Knížecí Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 29/03/2026 21:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 30/03/2026 23:00:00. 50 Economy ticket for £77 per person are available. Travel duration is 25h 10m
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FlixBus27h 0m006:20PragueČerný Most09:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 29/03/2026 06:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 30/03/2026 09:20:00. 50 Economy ticket for £70 per person are available. Travel duration is 27h 0m
Fastest Flights Sunday
Fastest Buses Sunday
Here you will find all operators and timetables for a
Bus from Prague to Rome
What are the most popular stations in Prague and Rome?
In Prague, you will usually depart from Wilsonova Coach Station, ÚAN Florenc or Černý Most, while in Rome you will be arriving at Termini Bus Station, Termini Central Station or Ostiense Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Rome from Prague? With 10 connections between 1 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Rome, you can pay as low as £37 with a Flight from LC Perú.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Ryanair: you will get to Rome in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Rome are FlixBus, LC Perú and Smartwings, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Prague and Rome is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Settebagni, and look at flights from Prague Airport, and landing at Rome Ciampino Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Prague to Rome?
The most popular companies between Prague and Rome, are FlixBus, LC Perú and Smartwings. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Airlines: LC Perú, Smartwings, Ryanair and 13 more.
All you need to know when you travel from Prague to Rome
Check all information on comfort and services on all modes of transports from Prague to Rome. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Prague to Rome
How can I reach Rome from Prague?
Every day, there are on average 10 connections between Flight and Bus, with which you can get to Rome from Prague.
How far is Rome from Prague?
The distance between Prague and Rome is 921.0 km.
What is the most ecofriendly mode of transport between Prague and Rome?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 157 kgs, and a flight 227 kgs.
What is the cheapest mode of transport from Prague to Rome?
You can get to Rome with just £37 by taking a Flight from LC Perú.
What is the fastest way to get from Prague to Rome?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Rome in just 1h 50m with a Flight from Ryanair.
More routes to Prague and to Rome
Looking for more options? Here you can see the most popular routes to Prague and to Rome. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Brno to Prague
- Budapest to Prague
- Cologne/Bonn Airport to Prague
- Dortmund to Prague
- Dresden to Prague
- Frankfurt am Main Airport to Prague
- Frankfurt am Main to Prague
- Hamburg to Prague
- Karlovy Vary to Prague
- Katowice to Prague
- Krakow to Prague
- Leipzig to Prague
- London to Prague
- Lyon to Prague
- Minsk to Prague
- Munich to Prague
- Nuremberg to Prague
- Rotterdam to Prague
- Salzburg to Prague
- Třebíč to Prague
- Vienna to Prague
- Zurich to Prague
- Trips to Rome
- Bari to Rome
- Benevento to Rome
- Brindisi to Rome
- Chieti to Rome
- Civitavecchia to Rome
- Cosenza to Rome
- Fisciano to Rome
- Florence to Rome
- Foggia to Rome
- Frascineto to Rome
- Grottammare to Rome
- Lamezia Terme to Rome
- Lauria to Rome
- Massafra to Rome
- Mercato San Severino to Rome
- Messina to Rome
- Mosciano Sant'Angelo to Rome
- Perugia to Rome
- Pescara to Rome
- Prato to Rome
- Siena to Rome
- Teramo to Rome
- Turin to Rome
- Venice to Rome
