What is the best way to travel from Prague to Rome?
Looking for a trip? Check and compare all the available Buses and Flights to Rome from Prague. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Rome from Prague?
You can reach Rome with just £49 by taking a Flight from Smartwings, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Skyscanner1h 50m019:30Prague AirportPrague Airport - T1/221:20Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 19:30:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 20/12/2025 21:20:00. 50 Economy ticket for £74 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m008:15Prague AirportPrague Airport - T1/210:05Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 08:15:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 20/12/2025 10:05:00. 50 Economy ticket for £79 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m014:25Prague AirportPrague Airport - T1/216:15Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 14:25:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 20/12/2025 16:15:00. 50 Economy ticket for £92 per person are available. Travel duration is 1h 50m
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Buzz11h 55m012:20Prague AirportPrague Airport - T1/200:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 12:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 21/12/2025 00:15:00. 50 Economy ticket for £98 per person are available. Travel duration is 11h 55m
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Air Malta11h 5m020:40Prague AirportPrague Airport - T1/207:45Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 20:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 21/12/2025 07:45:00. 50 Economy ticket for £98 per person are available. Travel duration is 11h 5m
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Skyscanner4h 25m018:10Prague AirportPrague Airport - T1/222:35Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 18:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 20/12/2025 22:35:00. 50 Economy ticket for £103 per person are available. Travel duration is 4h 25m
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FlixBus23h 20m022:20PragueRoztyly21:40RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 20/12/2025 22:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 21/12/2025 21:40:00. 50 Economy ticket for £102 per person are available. Travel duration is 23h 20m
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FlixBus27h 45m011:20Prague AirportPrague Airport - T1/215:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 11:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 21/12/2025 15:05:00. 50 Economy ticket for £111 per person are available. Travel duration is 27h 45m
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FlixBus21h 20m017:45PragueNa Knížecí Station15:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 20/12/2025 17:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 21/12/2025 15:05:00. 50 Economy ticket for £113 per person are available. Travel duration is 21h 20m
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 21/12/2025 18:00:00. 50 Economy ticket for £113 per person are available. Travel duration is 23h 10m
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FlixBus20h 25m013:05PragueWilsonova Coach Station09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 20/12/2025 13:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 09:30:00. 50 Economy ticket for £115 per person are available. Travel duration is 20h 25m
Cheapest Flights Saturday
Cheapest Buses Saturday
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 21/12/2025 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 22/12/2025 18:00:00. 50 Economy ticket for £106 per person are available. Travel duration is 23h 10m
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FlixBus20h 30m017:35PragueWilsonova Coach Station14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 21/12/2025 17:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 14:05:00. 50 Economy ticket for £108 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m017:20PragueÚAN Florenc14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 21/12/2025 17:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 14:05:00. 50 Economy ticket for £108 per person are available. Travel duration is 20h 45m
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FlixBus19h 35m017:45PragueNa Knížecí Station13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 21/12/2025 17:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 13:20:00. 50 Economy ticket for £118 per person are available. Travel duration is 19h 35m
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FlixBus24h 25m012:55PragueZličín13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 21/12/2025 12:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 13:20:00. 50 Economy ticket for £118 per person are available. Travel duration is 24h 25m
Cheapest Buses Sunday
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Buzz1h 50m017:50Prague AirportPrague Airport - T1/219:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 22/12/2025 17:50:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 22/12/2025 19:40:00. 50 Economy ticket for £98 per person are available. Travel duration is 1h 50m
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Volotea10h 15m008:35Prague AirportPrague Airport18:50Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Prague Airport, Prague Airport (Czech Republic) at 22/12/2025 08:35:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/12/2025 18:50:00. 50 Economy ticket for £102 per person are available. Travel duration is 10h 15m
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Smartwings1h 55m011:20Prague AirportPrague Airport13:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 22/12/2025 11:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/12/2025 13:15:00. 50 Economy ticket for £103 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m009:25Prague AirportPrague Airport - T1/211:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 22/12/2025 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/12/2025 11:20:00. 50 Economy ticket for £110 per person are available. Travel duration is 1h 55m
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LC Perú12h 35m022:35Prague AirportPrague Airport - T1/211:10Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 22/12/2025 22:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/12/2025 11:10:00. 50 Economy ticket for £116 per person are available. Travel duration is 12h 35m
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R Airlines25h 50m018:40Prague AirportPrague Airport - T1/220:30Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from R Airlines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 22/12/2025 18:40:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/12/2025 20:30:00. 50 Economy ticket for £120 per person are available. Travel duration is 25h 50m
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 22/12/2025 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 23/12/2025 18:00:00. 50 Economy ticket for £105 per person are available. Travel duration is 23h 10m
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FlixBus20h 30m017:35PragueWilsonova Coach Station14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 22/12/2025 17:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 14:05:00. 50 Economy ticket for £108 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m017:20PragueÚAN Florenc14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 22/12/2025 17:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 14:05:00. 50 Economy ticket for £108 per person are available. Travel duration is 20h 45m
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FlixBus22h 35m018:50Prague AirportPrague Airport - T1/217:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 22/12/2025 18:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 17:25:00. 50 Economy ticket for £108 per person are available. Travel duration is 22h 35m
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FlixBus19h 35m017:45PragueNa Knížecí Station13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 22/12/2025 17:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 13:20:00. 50 Economy ticket for £113 per person are available. Travel duration is 19h 35m
Cheapest Flights Monday
Cheapest Buses Monday
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Skyscanner1h 50m008:30Prague AirportPrague Airport - T1/210:20Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/12/2025 08:30:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/12/2025 10:20:00. 50 Economy ticket for £88 per person are available. Travel duration is 1h 50m
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Air Malta11h 5m020:40Prague AirportPrague Airport - T1/207:45Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/12/2025 20:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 24/12/2025 07:45:00. 50 Economy ticket for £99 per person are available. Travel duration is 11h 5m
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Buzz12h 5m009:35Prague AirportPrague Airport - T1/221:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/12/2025 09:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/12/2025 21:40:00. 50 Economy ticket for £104 per person are available. Travel duration is 12h 5m
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Buzz14h 0m005:55Prague AirportPrague Airport - T1/219:55Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/12/2025 05:55:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/12/2025 19:55:00. 50 Economy ticket for £107 per person are available. Travel duration is 14h 0m
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Buzz10h 10m021:50Prague AirportPrague Airport - T1/208:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/12/2025 21:50:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 24/12/2025 08:00:00. 50 Economy ticket for £115 per person are available. Travel duration is 10h 10m
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LC Perú1h 55m009:25Prague AirportPrague Airport - T1/211:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/12/2025 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/12/2025 11:20:00. 50 Economy ticket for £118 per person are available. Travel duration is 1h 55m
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FlixBus23h 10m023:50PragueWilsonova Coach Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 23/12/2025 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 23:00:00. 50 Economy ticket for £96 per person are available. Travel duration is 23h 10m
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FlixBus23h 25m023:35PragueÚAN Florenc23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 23/12/2025 23:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 23:00:00. 50 Economy ticket for £96 per person are available. Travel duration is 23h 25m
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FlixBus24h 45m022:15PragueNa Knížecí Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 23/12/2025 22:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 23:00:00. 50 Economy ticket for £96 per person are available. Travel duration is 24h 45m
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FlixBus21h 50m017:15PragueÚAN Florenc15:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 23/12/2025 17:15:00 to Anagnina Bus Station, Rome (Italy) arriving at 24/12/2025 15:05:00. 50 Economy ticket for £98 per person are available. Travel duration is 21h 50m
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FlixBus21h 50m017:15PragueWilsonova Coach Station15:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 23/12/2025 17:15:00 to Anagnina Bus Station, Rome (Italy) arriving at 24/12/2025 15:05:00. 50 Economy ticket for £98 per person are available. Travel duration is 21h 50m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
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FlixBus20h 45m017:20PragueÚAN Florenc14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 24/12/2025 17:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 14:05:00. 50 Economy ticket for £90 per person are available. Travel duration is 20h 45m
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FlixBus20h 30m017:35PragueWilsonova Coach Station14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 24/12/2025 17:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 14:05:00. 50 Economy ticket for £90 per person are available. Travel duration is 20h 30m
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FlixBus28h 15m018:45PragueWilsonova Coach Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 24/12/2025 18:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 23:00:00. 50 Economy ticket for £91 per person are available. Travel duration is 28h 15m
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FlixBus22h 50m014:30PragueČerný Most13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 24/12/2025 14:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 13:20:00. 50 Economy ticket for £92 per person are available. Travel duration is 22h 50m
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FlixBus20h 40m012:50PragueÚAN Florenc09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 24/12/2025 12:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 09:30:00. 50 Economy ticket for £92 per person are available. Travel duration is 20h 40m
Cheapest Buses Wednesday
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Smartwings1h 55m011:20Prague AirportPrague Airport - T1/213:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/12/2025 11:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 25/12/2025 13:15:00. 50 Economy ticket for £49 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m009:25Prague AirportPrague Airport - T1/211:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/12/2025 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 25/12/2025 11:20:00. 50 Economy ticket for £73 per person are available. Travel duration is 1h 55m
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Air Bagan8h 10m017:05Prague AirportPrague Airport - T1/201:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/12/2025 17:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 01:15:00. 50 Economy ticket for £88 per person are available. Travel duration is 8h 10m
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Wizz Air8h 10m017:05Prague AirportPrague Airport01:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 25/12/2025 17:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 01:15:00. 50 Economy ticket for £95 per person are available. Travel duration is 8h 10m
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Iberia8h 35m015:40Prague AirportPrague Airport - T1/200:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Iberia goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/12/2025 15:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 00:15:00. 50 Economy ticket for £130 per person are available. Travel duration is 8h 35m
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Air Bagan21h 50m017:05Prague AirportPrague Airport - T1/214:55Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/12/2025 17:05:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 26/12/2025 14:55:00. 50 Economy ticket for £143 per person are available. Travel duration is 21h 50m
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RegioJet20h 15m018:30PragueÚAN Florenc14:45RomeTiburtina Bus Station0EconomyA Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 25/12/2025 18:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/12/2025 14:45:00. 50 Economy ticket for £70 per person are available. Travel duration is 20h 15m
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FlixBus30h 40m011:20Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/12/2025 11:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 26/12/2025 18:00:00. 50 Economy ticket for £89 per person are available. Travel duration is 30h 40m
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FlixBus20h 30m017:35PragueWilsonova Coach Station14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 25/12/2025 17:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/12/2025 14:05:00. 50 Economy ticket for £96 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m017:20PragueÚAN Florenc14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 25/12/2025 17:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/12/2025 14:05:00. 50 Economy ticket for £96 per person are available. Travel duration is 20h 45m
Cheapest Flights Thursday
Cheapest Buses Thursday
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Smartwings1h 55m011:20Prague AirportPrague Airport13:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 26/12/2025 11:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 13:15:00. 50 Economy ticket for £91 per person are available. Travel duration is 1h 55m
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Air Serbia11h 45m020:30Prague AirportPrague Airport08:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Serbia goes from Prague Airport, Prague Airport (Czech Republic) at 26/12/2025 20:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/12/2025 08:15:00. 50 Economy ticket for £101 per person are available. Travel duration is 11h 45m
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Volotea10h 55m008:35Prague AirportPrague Airport19:30Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Prague Airport, Prague Airport (Czech Republic) at 26/12/2025 08:35:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 19:30:00. 50 Economy ticket for £128 per person are available. Travel duration is 10h 55m
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Brussels Airlines8h 35m011:40Prague AirportPrague Airport20:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Brussels Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 26/12/2025 11:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 20:15:00. 50 Economy ticket for £150 per person are available. Travel duration is 8h 35m
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EasyJet Airline10h 50m009:05Prague AirportPrague Airport19:55Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 26/12/2025 09:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 19:55:00. 50 Economy ticket for £167 per person are available. Travel duration is 10h 50m
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FlixBus27h 25m006:05PragueWilsonova Coach Station09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 26/12/2025 06:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 09:30:00. 50 Economy ticket for £111 per person are available. Travel duration is 27h 25m
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FlixBus24h 25m012:55PragueZličín13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 26/12/2025 12:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 13:20:00. 50 Economy ticket for £112 per person are available. Travel duration is 24h 25m
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FlixBus27h 45m011:20Prague AirportPrague Airport - T1/215:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/12/2025 11:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 27/12/2025 15:05:00. 50 Economy ticket for £112 per person are available. Travel duration is 27h 45m
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FlixBus22h 50m014:30PragueČerný Most13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 26/12/2025 14:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 13:20:00. 50 Economy ticket for £113 per person are available. Travel duration is 22h 50m
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FlixBus19h 35m017:45PragueNa Knížecí Station13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 26/12/2025 17:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 13:20:00. 50 Economy ticket for £113 per person are available. Travel duration is 19h 35m
Cheapest Flights Friday
Cheapest Buses Friday
What are the fastest trips from Prague to Rome?
You can get to Rome from Prague in just 1h 50m with a Flight from Skyscanner. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Skyscanner1h 50m019:30Prague AirportPrague Airport - T1/221:20Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 19:30:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 20/12/2025 21:20:00. 50 Economy ticket for £74 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m008:15Prague AirportPrague Airport - T1/210:05Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 08:15:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 20/12/2025 10:05:00. 50 Economy ticket for £79 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m014:25Prague AirportPrague Airport - T1/216:15Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 14:25:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 20/12/2025 16:15:00. 50 Economy ticket for £92 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m009:25Prague AirportPrague Airport - T1/211:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 20/12/2025 11:20:00. 50 Economy ticket for £109 per person are available. Travel duration is 1h 55m
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Skyscanner4h 25m018:10Prague AirportPrague Airport - T1/222:35Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 18:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 20/12/2025 22:35:00. 50 Economy ticket for £103 per person are available. Travel duration is 4h 25m
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Air Malta11h 5m020:40Prague AirportPrague Airport - T1/207:45Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 20:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 21/12/2025 07:45:00. 50 Economy ticket for £98 per person are available. Travel duration is 11h 5m
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FlixBus20h 25m013:05PragueWilsonova Coach Station09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 20/12/2025 13:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 09:30:00. 50 Economy ticket for £115 per person are available. Travel duration is 20h 25m
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FlixBus21h 20m017:45PragueNa Knížecí Station15:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 20/12/2025 17:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 21/12/2025 15:05:00. 50 Economy ticket for £113 per person are available. Travel duration is 21h 20m
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 21/12/2025 18:00:00. 50 Economy ticket for £113 per person are available. Travel duration is 23h 10m
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FlixBus23h 20m022:20PragueRoztyly21:40RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Roztyly, Prague (Czech Republic) at 20/12/2025 22:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 21/12/2025 21:40:00. 50 Economy ticket for £102 per person are available. Travel duration is 23h 20m
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FlixBus27h 45m011:20Prague AirportPrague Airport - T1/215:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 20/12/2025 11:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 21/12/2025 15:05:00. 50 Economy ticket for £111 per person are available. Travel duration is 27h 45m
Fastest Flights Saturday
Fastest Buses Saturday
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FlixBus19h 35m017:45PragueNa Knížecí Station13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 21/12/2025 17:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 13:20:00. 50 Economy ticket for £118 per person are available. Travel duration is 19h 35m
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FlixBus20h 30m017:35PragueWilsonova Coach Station14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 21/12/2025 17:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 14:05:00. 50 Economy ticket for £108 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m017:20PragueÚAN Florenc14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 21/12/2025 17:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 14:05:00. 50 Economy ticket for £108 per person are available. Travel duration is 20h 45m
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 21/12/2025 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 22/12/2025 18:00:00. 50 Economy ticket for £106 per person are available. Travel duration is 23h 10m
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FlixBus24h 25m012:55PragueZličín13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 21/12/2025 12:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 13:20:00. 50 Economy ticket for £118 per person are available. Travel duration is 24h 25m
Fastest Buses Sunday
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Buzz1h 50m017:50Prague AirportPrague Airport - T1/219:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 22/12/2025 17:50:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 22/12/2025 19:40:00. 50 Economy ticket for £98 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m008:15Prague AirportPrague Airport - T1/210:05Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 22/12/2025 08:15:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 22/12/2025 10:05:00. 50 Economy ticket for £131 per person are available. Travel duration is 1h 50m
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Smartwings1h 55m011:20Prague AirportPrague Airport13:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 22/12/2025 11:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/12/2025 13:15:00. 50 Economy ticket for £103 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m009:25Prague AirportPrague Airport - T1/211:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 22/12/2025 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/12/2025 11:20:00. 50 Economy ticket for £110 per person are available. Travel duration is 1h 55m
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Buzz5h 15m015:40Prague AirportPrague Airport - T1/220:55Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 22/12/2025 15:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/12/2025 20:55:00. 50 Economy ticket for £135 per person are available. Travel duration is 5h 15m
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LOT Polish Airlines / Polskie Linie Lotnicze5h 40m012:55Prague AirportPrague Airport - T1/218:35Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 22/12/2025 12:55:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/12/2025 18:35:00. 50 Economy ticket for £153 per person are available. Travel duration is 5h 40m
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FlixBus19h 35m017:45PragueNa Knížecí Station13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 22/12/2025 17:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 13:20:00. 50 Economy ticket for £113 per person are available. Travel duration is 19h 35m
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FlixBus20h 30m017:35PragueWilsonova Coach Station14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 22/12/2025 17:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 14:05:00. 50 Economy ticket for £108 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m017:20PragueÚAN Florenc14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 22/12/2025 17:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 14:05:00. 50 Economy ticket for £108 per person are available. Travel duration is 20h 45m
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FlixBus22h 35m018:50Prague AirportPrague Airport - T1/217:25RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 22/12/2025 18:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 17:25:00. 50 Economy ticket for £108 per person are available. Travel duration is 22h 35m
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FlixBus23h 10m018:50Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 22/12/2025 18:50:00 to Anagnina Bus Station, Rome (Italy) arriving at 23/12/2025 18:00:00. 50 Economy ticket for £105 per person are available. Travel duration is 23h 10m
Fastest Flights Monday
Fastest Buses Monday
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Skyscanner1h 50m008:30Prague AirportPrague Airport - T1/210:20Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/12/2025 08:30:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/12/2025 10:20:00. 50 Economy ticket for £88 per person are available. Travel duration is 1h 50m
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Skyscanner1h 50m014:35Prague AirportPrague Airport - T1/216:25Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Skyscanner goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/12/2025 14:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/12/2025 16:25:00. 50 Economy ticket for £161 per person are available. Travel duration is 1h 50m
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LC Perú1h 55m009:25Prague AirportPrague Airport - T1/211:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/12/2025 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/12/2025 11:20:00. 50 Economy ticket for £118 per person are available. Travel duration is 1h 55m
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Buzz10h 10m021:50Prague AirportPrague Airport - T1/208:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/12/2025 21:50:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 24/12/2025 08:00:00. 50 Economy ticket for £115 per person are available. Travel duration is 10h 10m
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Buzz10h 15m021:50Prague AirportPrague Airport - T1/208:05Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Buzz goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/12/2025 21:50:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 24/12/2025 08:05:00. 50 Economy ticket for £121 per person are available. Travel duration is 10h 15m
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Air Malta11h 5m020:40Prague AirportPrague Airport - T1/207:45Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 23/12/2025 20:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 24/12/2025 07:45:00. 50 Economy ticket for £99 per person are available. Travel duration is 11h 5m
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FlixBus21h 50m017:15PragueÚAN Florenc15:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 23/12/2025 17:15:00 to Anagnina Bus Station, Rome (Italy) arriving at 24/12/2025 15:05:00. 50 Economy ticket for £98 per person are available. Travel duration is 21h 50m
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FlixBus21h 50m017:15PragueWilsonova Coach Station15:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 23/12/2025 17:15:00 to Anagnina Bus Station, Rome (Italy) arriving at 24/12/2025 15:05:00. 50 Economy ticket for £98 per person are available. Travel duration is 21h 50m
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FlixBus23h 10m023:50PragueWilsonova Coach Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 23/12/2025 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 23:00:00. 50 Economy ticket for £96 per person are available. Travel duration is 23h 10m
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FlixBus23h 25m023:35PragueÚAN Florenc23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 23/12/2025 23:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 23:00:00. 50 Economy ticket for £96 per person are available. Travel duration is 23h 25m
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FlixBus24h 45m022:15PragueNa Knížecí Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 23/12/2025 22:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 23:00:00. 50 Economy ticket for £96 per person are available. Travel duration is 24h 45m
Fastest Flights Tuesday
Fastest Buses Tuesday
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FlixBus20h 30m017:35PragueWilsonova Coach Station14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 24/12/2025 17:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 14:05:00. 50 Economy ticket for £90 per person are available. Travel duration is 20h 30m
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FlixBus20h 40m012:50PragueÚAN Florenc09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 24/12/2025 12:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 09:30:00. 50 Economy ticket for £92 per person are available. Travel duration is 20h 40m
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FlixBus20h 45m017:20PragueÚAN Florenc14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 24/12/2025 17:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 14:05:00. 50 Economy ticket for £90 per person are available. Travel duration is 20h 45m
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FlixBus22h 50m014:30PragueČerný Most13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 24/12/2025 14:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 13:20:00. 50 Economy ticket for £92 per person are available. Travel duration is 22h 50m
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FlixBus28h 15m018:45PragueWilsonova Coach Station23:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 24/12/2025 18:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 23:00:00. 50 Economy ticket for £91 per person are available. Travel duration is 28h 15m
Fastest Buses Wednesday
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Smartwings1h 55m011:20Prague AirportPrague Airport - T1/213:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/12/2025 11:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 25/12/2025 13:15:00. 50 Economy ticket for £49 per person are available. Travel duration is 1h 55m
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LC Perú1h 55m009:25Prague AirportPrague Airport - T1/211:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/12/2025 09:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 25/12/2025 11:20:00. 50 Economy ticket for £73 per person are available. Travel duration is 1h 55m
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Air Bagan8h 10m017:05Prague AirportPrague Airport - T1/201:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Bagan goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/12/2025 17:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 01:15:00. 50 Economy ticket for £88 per person are available. Travel duration is 8h 10m
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Wizz Air8h 10m017:05Prague AirportPrague Airport01:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Prague Airport, Prague Airport (Czech Republic) at 25/12/2025 17:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 01:15:00. 50 Economy ticket for £95 per person are available. Travel duration is 8h 10m
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Iberia8h 35m015:40Prague AirportPrague Airport - T1/200:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Iberia goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/12/2025 15:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 00:15:00. 50 Economy ticket for £130 per person are available. Travel duration is 8h 35m
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Swiss International Air Lines15h 25m020:15Prague AirportPrague Airport - T1/211:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Swiss International Air Lines goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/12/2025 20:15:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 26/12/2025 11:40:00. 50 Economy ticket for £322 per person are available. Travel duration is 15h 25m
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RegioJet20h 15m018:30PragueÚAN Florenc14:45RomeTiburtina Bus Station0EconomyA Bus from RegioJet goes from ÚAN Florenc, Prague (Czech Republic) at 25/12/2025 18:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/12/2025 14:45:00. 50 Economy ticket for £70 per person are available. Travel duration is 20h 15m
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FlixBus20h 30m017:35PragueWilsonova Coach Station14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 25/12/2025 17:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/12/2025 14:05:00. 50 Economy ticket for £96 per person are available. Travel duration is 20h 30m
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FlixBus20h 45m017:20PragueÚAN Florenc14:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from ÚAN Florenc, Prague (Czech Republic) at 25/12/2025 17:20:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/12/2025 14:05:00. 50 Economy ticket for £96 per person are available. Travel duration is 20h 45m
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FlixBus30h 40m011:20Prague AirportPrague Airport - T1/218:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 25/12/2025 11:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 26/12/2025 18:00:00. 50 Economy ticket for £89 per person are available. Travel duration is 30h 40m
Fastest Flights Thursday
Fastest Buses Thursday
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Smartwings1h 55m011:20Prague AirportPrague Airport13:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Smartwings goes from Prague Airport, Prague Airport (Czech Republic) at 26/12/2025 11:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 13:15:00. 50 Economy ticket for £91 per person are available. Travel duration is 1h 55m
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Brussels Airlines8h 35m011:40Prague AirportPrague Airport20:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Brussels Airlines goes from Prague Airport, Prague Airport (Czech Republic) at 26/12/2025 11:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 20:15:00. 50 Economy ticket for £150 per person are available. Travel duration is 8h 35m
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EasyJet Airline10h 50m009:05Prague AirportPrague Airport19:55Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Prague Airport, Prague Airport (Czech Republic) at 26/12/2025 09:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 19:55:00. 50 Economy ticket for £167 per person are available. Travel duration is 10h 50m
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Volotea10h 55m008:35Prague AirportPrague Airport19:30Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Prague Airport, Prague Airport (Czech Republic) at 26/12/2025 08:35:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 19:30:00. 50 Economy ticket for £128 per person are available. Travel duration is 10h 55m
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Air Serbia11h 45m020:30Prague AirportPrague Airport08:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Serbia goes from Prague Airport, Prague Airport (Czech Republic) at 26/12/2025 20:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/12/2025 08:15:00. 50 Economy ticket for £101 per person are available. Travel duration is 11h 45m
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FlixBus19h 35m017:45PragueNa Knížecí Station13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Na Knížecí Station, Prague (Czech Republic) at 26/12/2025 17:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 13:20:00. 50 Economy ticket for £113 per person are available. Travel duration is 19h 35m
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FlixBus22h 50m014:30PragueČerný Most13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Černý Most, Prague (Czech Republic) at 26/12/2025 14:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 13:20:00. 50 Economy ticket for £113 per person are available. Travel duration is 22h 50m
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FlixBus24h 25m012:55PragueZličín13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Zličín, Prague (Czech Republic) at 26/12/2025 12:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 13:20:00. 50 Economy ticket for £112 per person are available. Travel duration is 24h 25m
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FlixBus27h 25m006:05PragueWilsonova Coach Station09:30RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Wilsonova Coach Station, Prague (Czech Republic) at 26/12/2025 06:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 09:30:00. 50 Economy ticket for £111 per person are available. Travel duration is 27h 25m
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FlixBus27h 45m011:20Prague AirportPrague Airport - T1/215:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Prague Airport - T1/2, Prague Airport (Czech Republic) at 26/12/2025 11:20:00 to Anagnina Bus Station, Rome (Italy) arriving at 27/12/2025 15:05:00. 50 Economy ticket for £112 per person are available. Travel duration is 27h 45m
Fastest Flights Friday
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from Prague to Rome
What are the most popular stations in Prague and Rome?
In Prague, you will usually depart from Wilsonova Coach Station, ÚAN Florenc or Černý Most, while in Rome you will be arriving at Termini Bus Station, Termini Central Station or Ostiense Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Rome from Prague? With 11 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Prague and Rome, you can pay as low as £49 with a Flight from Smartwings.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Rome in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Prague and Rome are FlixBus, Buzz and Skyscanner, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Prague and Rome is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Horoměřice or to Settebagni, and look at flights from Prague Airport, and landing at Rome Ciampino Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Prague to Rome?
The most popular companies between Prague and Rome, are FlixBus, Buzz and Skyscanner. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and RegioJet
Airlines: Buzz, Skyscanner, LC Perú and 15 more.
All you need to know when you travel from Prague to Rome
Check all information on comfort and services on all modes of transports from Prague to Rome. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Prague to Rome
How can I reach Rome from Prague?
Every day, there are on average 11 connections between Bus and Flight, with which you can get to Rome from Prague.
How far is Rome from Prague?
The distance between Prague and Rome is 921.0 km.
What is the most ecofriendly mode of transport between Prague and Rome?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 25 kgs of CO2, a train 32 kgs, a car 157 kgs, and a flight 227 kgs.
What is the cheapest mode of transport from Prague to Rome?
You can get to Rome with just £49 by taking a Flight from Smartwings.
What is the fastest way to get from Prague to Rome?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Rome in just 1h 50m with a Flight from Skyscanner.
More routes to Prague and to Rome
Looking for more options? Here you can see the most popular routes to Prague and to Rome. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Brno to Prague
- Budapest to Prague
- Česká Lípa to Prague
- Dresden to Prague
- Florence to Prague
- Karlovy Vary to Prague
- Katowice to Prague
- Krakow to Prague
- Linz to Prague
- London to Prague
- Lyon to Prague
- Milan to Prague
- Minsk to Prague
- Munich to Prague
- Nuremberg to Prague
- Paris to Prague
- Pelhřimov to Prague
- Rome to Prague
- Třebíč to Prague
- Vienna to Prague
- Vilnius to Prague
- Zurich to Prague
- Trips to Rome
- Avellino to Rome
- Bari to Rome
- Battipaglia to Rome
- Caserta to Rome
- Cassino to Rome
- Chieti to Rome
- Civitanova to Rome
- Gallipoli to Rome
- Grottaminarda to Rome
- L'Aquila to Rome
- Lagonegro to Rome
- Lamezia Terme to Rome
- Lecce to Rome
- Milan to Rome
- Mosciano Sant'Angelo to Rome
- Naples to Rome
- Palermo to Rome
- Pescara to Rome
- Porto D'Ascoli to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Sarno to Rome
