Which bus from Lyon to Rome is the best?
Check the bus schedule for Lyon to Rome. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or Itabus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 09:15 | Lyon | Perrache Bus Stop | 23:45 | Rome | Tiburtina Bus Station | Premium Economy | £39 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 17/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 17/12/2025 23:45:00. 50 Premium Economy ticket for £39 per person are available. Travel duration is 14h 30m
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| Itabus | 15h 30m | 15:30 | Lyon | Perrache Bus Stop | 07:00 | Rome | Tiburtina Bus Station | Premium Economy | £39 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 17/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/12/2025 07:00:00. 50 Premium Economy ticket for £39 per person are available. Travel duration is 15h 30m
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| FlixBus | 16h 0m | 18:00 | Lyon | Perrache Bus Stop | 10:00 | Rome | Tiburtina Bus Station | Economy | £80 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 17/12/2025 18:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/12/2025 10:00:00. 50 Economy ticket for £80 per person are available. Travel duration is 16h 0m
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| FlixBus | 17h 35m | 12:35 | Lyon | Perrache Bus Stop | 06:10 | Rome | Tiburtina Bus Station | Economy | £84 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 17/12/2025 12:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/12/2025 06:10:00. 50 Economy ticket for £84 per person are available. Travel duration is 17h 35m
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| FlixBus | 16h 55m | 14:55 | Lyon | Perrache Bus Stop | 07:50 | Rome | Tiburtina Bus Station | Economy | £85 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 17/12/2025 14:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/12/2025 07:50:00. 50 Economy ticket for £85 per person are available. Travel duration is 16h 55m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 15h 30m | 15:30 | Lyon | Perrache Bus Stop | 07:00 | Rome | Tiburtina Bus Station | Premium Economy | £34 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 18/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 07:00:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 15h 30m
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| Itabus | 14h 30m | 09:15 | Lyon | Perrache Bus Stop | 23:45 | Rome | Tiburtina Bus Station | Premium Economy | £48 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 18/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/12/2025 23:45:00. 50 Premium Economy ticket for £48 per person are available. Travel duration is 14h 30m
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| FlixBus | 14h 50m | 01:15 | Lyon | Perrache Bus Stop | 16:05 | Rome | Tiburtina Bus Station | Economy | £67 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 18/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/12/2025 16:05:00. 50 Economy ticket for £67 per person are available. Travel duration is 14h 50m
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| FlixBus | 15h 30m | 20:45 | Lyon | Perrache Bus Stop | 12:15 | Rome | Anagnina Bus Station | Economy | £72 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 18/12/2025 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 19/12/2025 12:15:00. 50 Economy ticket for £72 per person are available. Travel duration is 15h 30m
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| FlixBus | 16h 35m | 20:45 | Lyon | Perrache Bus Stop | 13:20 | Rome | Tiburtina Bus Station | Economy | £80 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 18/12/2025 20:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 13:20:00. 50 Economy ticket for £80 per person are available. Travel duration is 16h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 15h 30m | 15:30 | Lyon | Perrache Bus Stop | 07:00 | Rome | Tiburtina Bus Station | Economy | £50 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 19/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 20/12/2025 07:00:00. 50 Economy ticket for £50 per person are available. Travel duration is 15h 30m
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| Itabus | 14h 30m | 09:15 | Lyon | Perrache Bus Stop | 23:45 | Rome | Tiburtina Bus Station | Premium Economy | £53 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 19/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 23:45:00. 50 Premium Economy ticket for £53 per person are available. Travel duration is 14h 30m
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| Itabus | 19h 50m | 23:50 | Lyon | Perrache Bus Stop | 19:40 | Rome | Tiburtina Bus Station | Premium Economy | £61 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 19/12/2025 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 20/12/2025 19:40:00. 50 Premium Economy ticket for £61 per person are available. Travel duration is 19h 50m
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| FlixBus | 14h 50m | 01:15 | Lyon | Perrache Bus Stop | 16:05 | Rome | Tiburtina Bus Station | Economy | £72 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 19/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 16:05:00. 50 Economy ticket for £72 per person are available. Travel duration is 14h 50m
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| FlixBus | 14h 10m | 09:35 | Lyon | Perrache Bus Stop | 23:45 | Rome | Tiburtina Bus Station | Economy | £79 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 19/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 23:45:00. 50 Economy ticket for £79 per person are available. Travel duration is 14h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 14h 30m | 09:15 | Lyon | Perrache Bus Stop | 23:45 | Rome | Tiburtina Bus Station | Premium Economy | £51 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 20/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 20/12/2025 23:45:00. 50 Premium Economy ticket for £51 per person are available. Travel duration is 14h 30m
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| Itabus | 19h 50m | 23:50 | Lyon | Perrache Bus Stop | 19:40 | Rome | Tiburtina Bus Station | Premium Economy | £53 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 20/12/2025 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 19:40:00. 50 Premium Economy ticket for £53 per person are available. Travel duration is 19h 50m
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| Itabus | 15h 30m | 15:30 | Lyon | Perrache Bus Stop | 07:00 | Rome | Tiburtina Bus Station | Premium Economy | £61 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 20/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 07:00:00. 50 Premium Economy ticket for £61 per person are available. Travel duration is 15h 30m
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| FlixBus | 16h 5m | 14:55 | Lyon | Perrache Bus Stop | 07:00 | Rome | Tiburtina Bus Station | Economy | £94 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 20/12/2025 14:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 07:00:00. 50 Economy ticket for £94 per person are available. Travel duration is 16h 5m
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| FlixBus | 14h 50m | 01:15 | Lyon | Perrache Bus Stop | 16:05 | Rome | Tiburtina Bus Station | Economy | £95 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 20/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 20/12/2025 16:05:00. 50 Economy ticket for £95 per person are available. Travel duration is 14h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 15h 30m | 15:30 | Lyon | Perrache Bus Stop | 07:00 | Rome | Tiburtina Bus Station | Premium Economy | £46 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 07:00:00. 50 Premium Economy ticket for £46 per person are available. Travel duration is 15h 30m
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| Itabus | 14h 30m | 09:15 | Lyon | Perrache Bus Stop | 23:45 | Rome | Tiburtina Bus Station | Premium Economy | £51 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 23:45:00. 50 Premium Economy ticket for £51 per person are available. Travel duration is 14h 30m
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| Itabus | 19h 50m | 23:50 | Lyon | Perrache Bus Stop | 19:40 | Rome | Tiburtina Bus Station | Premium Economy | £60 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 19:40:00. 50 Premium Economy ticket for £60 per person are available. Travel duration is 19h 50m
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| FlixBus | 14h 10m | 09:35 | Lyon | Perrache Bus Stop | 23:45 | Rome | Tiburtina Bus Station | Economy | £72 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 23:45:00. 50 Economy ticket for £72 per person are available. Travel duration is 14h 10m
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| FlixBus | 14h 50m | 01:15 | Lyon | Perrache Bus Stop | 16:05 | Rome | Tiburtina Bus Station | Economy | £88 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 16:05:00. 50 Economy ticket for £88 per person are available. Travel duration is 14h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 15h 30m | 15:30 | Lyon | Perrache Bus Stop | 07:00 | Rome | Tiburtina Coach Station | Basic | £47 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 22/12/2025 15:30:00 to Tiburtina Coach Station, Rome (Italy) arriving at 23/12/2025 07:00:00. 50 Basic ticket for £47 per person are available. Travel duration is 15h 30m
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| FlixBus | 14h 10m | 09:35 | Lyon | Perrache Bus Stop | 23:45 | Rome | Tiburtina Bus Station | Economy | £67 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 22/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 23:45:00. 50 Economy ticket for £67 per person are available. Travel duration is 14h 10m
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| Itabus | 14h 30m | 09:15 | Lyon | Perrache Bus Stop | 23:45 | Rome | Tiburtina Bus Station | Premium Economy | £70 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 22/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 23:45:00. 50 Premium Economy ticket for £70 per person are available. Travel duration is 14h 30m
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| FlixBus | 14h 50m | 01:15 | Lyon | Perrache Bus Stop | 16:05 | Rome | Tiburtina Bus Station | Economy | £79 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 22/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 16:05:00. 50 Economy ticket for £79 per person are available. Travel duration is 14h 50m
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| FlixBus | 15h 50m | 16:00 | Lyon | Perrache Bus Stop | 07:50 | Rome | Tiburtina Bus Station | Economy | £81 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 22/12/2025 16:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 07:50:00. 50 Economy ticket for £81 per person are available. Travel duration is 15h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Itabus | 15h 30m | 15:30 | Lyon | Perrache Bus Stop | 07:00 | Rome | Tiburtina Bus Station | Premium Economy | £46 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 23/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 07:00:00. 50 Premium Economy ticket for £46 per person are available. Travel duration is 15h 30m
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| Itabus | 14h 30m | 09:15 | Lyon | Perrache Bus Stop | 23:45 | Rome | Tiburtina Bus Station | Premium Economy | £51 |
A Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 23/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 23:45:00. 50 Premium Economy ticket for £51 per person are available. Travel duration is 14h 30m
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| FlixBus | 14h 50m | 01:15 | Lyon | Perrache Bus Stop | 16:05 | Rome | Tiburtina Bus Station | Economy | £70 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 23/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 16:05:00. 50 Economy ticket for £70 per person are available. Travel duration is 14h 50m
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| FlixBus | 14h 10m | 09:35 | Lyon | Perrache Bus Stop | 23:45 | Rome | Tiburtina Bus Station | Economy | £76 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 23/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 23:45:00. 50 Economy ticket for £76 per person are available. Travel duration is 14h 10m
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| FlixBus | 16h 5m | 14:55 | Lyon | Perrache Bus Stop | 07:00 | Rome | Tiburtina Bus Station | Economy | £86 |
A Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 23/12/2025 14:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 07:00:00. 50 Economy ticket for £86 per person are available. Travel duration is 16h 5m
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Best Price Offer: The price for the cheapest coach from Lyon to Rome is £25 on 07/01/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Lyon and Rome?
All facts for Lyon to Rome bus at a glance
Compare all coach operators like FlixBus and Itabus that travel daily 19 times by bus from Lyon to Rome in one click. Book your Lyon to Rome bus ticket starting from £25!
| Cheapest Bus | £25 |
| Fastest Bus | 14h 10m |
| Earliest Coach | 09:15 |
| Latest Coach | 23:00 |
| Daily Bus Connections | 19 Ø |
| Distance | 749.0 km |
| Coach Companies | FlixBus and Itabus |
What are the cheapest coach tickets from Lyon to Rome?
Every day, 19 buses from 2 coach companies leave Lyon for Rome. Check the table below to find the cheapest prices for coach tickets for this route, starting from 17/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Lyon to Rome
How to save money travelling from Lyon to Rome
Book the ticket from Lyon to Rome in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Lyon to Rome, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Lyon to Rome are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
What are the most popular bus companies from Lyon to Rome?
Itabus from Lyon to Rome
Here you will find the key facts about the Itabus bus route Lyon to Rome:
| Cheapest Price | £34 |
| Fastest Coach | 14h 30m |
| Earliest Coach | 09:15 |
| Last Coach | 15:30 |
| Daily Connections | 9 Ø |
| Found on | 17/12/2025 |
All bus stations and stops in Lyon and Rome
Here is a map with all coach stations in Lyon and Rome. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Lyon to Rome
FAQs for Lyon to Rome bus
How much does a Lyon Rome coach trip cost?
How much could I save by comparing buses from Lyon to Rome?
How many connections are available for the Lyon Rome route on average every day?
How long does a bus to Rome from Lyon take?
What time is the first bus from Lyon to Rome?
What time is the last coach from Lyon to Rome?
Which bus companies serve the Lyon Rome route?
Is there a direct bus between Lyon and Rome?
What can I take with me on the bus to Rome from Lyon?
What equipment is available for the Lyon Rome bus route?
How does CheckMyBus find the best coach deals from Lyon to Rome?
How does CheckMyBus technology work for trips from Lyon to Rome?
Available seat classes which are offered on the bus route Lyon to Rome
Name referring to the typical seat you will find with companies that don’t distinguish between different classes.
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
More bus routes to Lyon and to Rome
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