What is the best way to travel from Lyon to Rome?
Looking for a trip? Check and compare all the available Buses, Flights and Trains to Rome from Lyon. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 4 available companies to find your perfect trip!
What is the cheapest way to reach Rome from Lyon?
You can reach Rome with just £47 by taking a Bus from Itabus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 07:00:00. 50 Premium Economy ticket for £66 per person are available. Travel duration is 15h 30m
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FlixBus17h 30m012:35LyonPerrache Bus Stop06:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 12:35:00 to Anagnina Bus Station, Rome (Italy) arriving at 22/12/2025 06:05:00. 50 Economy ticket for £97 per person are available. Travel duration is 17h 30m
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FlixBus16h 0m018:00LyonPerrache Bus Stop10:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 18:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 10:00:00. 50 Economy ticket for £97 per person are available. Travel duration is 16h 0m
Cheapest Buses Sunday
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Coach Station0BasicA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 22/12/2025 15:30:00 to Tiburtina Coach Station, Rome (Italy) arriving at 23/12/2025 07:00:00. 50 Basic ticket for £48 per person are available. Travel duration is 15h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 22/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 07:00:00. 50 Premium Economy ticket for £54 per person are available. Travel duration is 15h 30m
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FlixBus14h 10m009:35LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 22/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 23:45:00. 50 Economy ticket for £79 per person are available. Travel duration is 14h 10m
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FlixBus16h 0m018:00LyonPerrache Bus Stop10:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 22/12/2025 18:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 10:00:00. 50 Economy ticket for £83 per person are available. Travel duration is 16h 0m
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Volotea9h 55m014:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station00:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 22/12/2025 14:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/12/2025 00:05:00. 50 Economy ticket for £65 per person are available. Travel duration is 9h 55m
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EasyJet Airline8h 15m007:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station15:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 22/12/2025 07:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/12/2025 15:15:00. 50 Economy ticket for £105 per person are available. Travel duration is 8h 15m
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LC Perú7h 25m008:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station16:00Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 22/12/2025 08:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 22/12/2025 16:00:00. 50 Economy ticket for £145 per person are available. Travel duration is 7h 25m
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Wizz Air18h 10m016:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station10:50Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Wizz Air goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 22/12/2025 16:40:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/12/2025 10:50:00. 50 Economy ticket for £171 per person are available. Travel duration is 18h 10m
Cheapest Buses Monday
Cheapest Flights Monday
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 23/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 07:00:00. 50 Premium Economy ticket for £48 per person are available. Travel duration is 15h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Coach Station0BasicA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 23/12/2025 15:30:00 to Tiburtina Coach Station, Rome (Italy) arriving at 24/12/2025 07:00:00. 50 Basic ticket for £50 per person are available. Travel duration is 15h 30m
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FlixBus14h 10m009:35LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 23/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 23:45:00. 50 Economy ticket for £79 per person are available. Travel duration is 14h 10m
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FlixBus15h 50m016:00LyonPerrache Bus Stop07:50RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 23/12/2025 16:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 07:50:00. 50 Economy ticket for £87 per person are available. Travel duration is 15h 50m
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Volotea27h 30m019:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station23:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/12/2025 19:55:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 24/12/2025 23:25:00. 50 Economy ticket for £83 per person are available. Travel duration is 27h 30m
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EasyJet Airline16h 55m007:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station23:55Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/12/2025 07:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/12/2025 23:55:00. 50 Economy ticket for £99 per person are available. Travel duration is 16h 55m
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Skyscanner1h 35m018:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/12/2025 18:50:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/12/2025 20:25:00. 50 Economy ticket for £120 per person are available. Travel duration is 1h 35m
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EasyJet Airline10h 30m010:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:30Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/12/2025 10:00:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/12/2025 20:30:00. 50 Economy ticket for £158 per person are available. Travel duration is 10h 30m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 24/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 23:45:00. 50 Premium Economy ticket for £48 per person are available. Travel duration is 14h 30m
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FlixBus15h 30m020:45LyonPerrache Bus Stop12:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 24/12/2025 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 25/12/2025 12:15:00. 50 Economy ticket for £68 per person are available. Travel duration is 15h 30m
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FlixBus14h 50m001:15LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 24/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 16:05:00. 50 Economy ticket for £72 per person are available. Travel duration is 14h 50m
Cheapest Buses Wednesday
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BlaBlaCar Bus14h 45m005:30LyonPerrache Bus Stop20:15RomeTiburtina Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Bus Stop, Lyon (France) at 25/12/2025 05:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 20:15:00. 50 Economy ticket for £48 per person are available. Travel duration is 14h 45m
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 25/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 23:45:00. 50 Premium Economy ticket for £49 per person are available. Travel duration is 14h 30m
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FlixBus14h 50m001:15LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 25/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 16:05:00. 50 Economy ticket for £59 per person are available. Travel duration is 14h 50m
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FlixBus15h 30m020:45LyonPerrache Bus Stop12:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 25/12/2025 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 26/12/2025 12:15:00. 50 Economy ticket for £70 per person are available. Travel duration is 15h 30m
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LC Perú12h 5m009:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:35Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 25/12/2025 09:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 25/12/2025 21:35:00. 50 Economy ticket for £56 per person are available. Travel duration is 12h 5m
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LC Perú25h 50m008:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station10:25Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 25/12/2025 08:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 26/12/2025 10:25:00. 50 Economy ticket for £80 per person are available. Travel duration is 25h 50m
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Air Malta11h 45m020:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station07:45Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 25/12/2025 20:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 07:45:00. 50 Economy ticket for £85 per person are available. Travel duration is 11h 45m
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Air Bagan26h 15m014:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station16:45Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Air Bagan goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 25/12/2025 14:30:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 26/12/2025 16:45:00. 50 Economy ticket for £132 per person are available. Travel duration is 26h 15m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Itabus19h 50m023:50LyonPerrache Bus Stop19:40RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 26/12/2025 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 19:40:00. 50 Premium Economy ticket for £47 per person are available. Travel duration is 19h 50m
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BlaBlaCar Bus14h 45m005:30LyonPerrache Bus Stop20:15RomeTiburtina Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Bus Stop, Lyon (France) at 26/12/2025 05:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/12/2025 20:15:00. 50 Economy ticket for £48 per person are available. Travel duration is 14h 45m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 26/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 07:00:00. 50 Premium Economy ticket for £48 per person are available. Travel duration is 15h 30m
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FlixBus14h 50m001:15LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 26/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/12/2025 16:05:00. 50 Economy ticket for £70 per person are available. Travel duration is 14h 50m
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LC Perú12h 30m008:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 26/12/2025 08:35:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 21:05:00. 50 Economy ticket for £108 per person are available. Travel duration is 12h 30m
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LC Perú11h 5m008:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station19:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 26/12/2025 08:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 26/12/2025 19:40:00. 50 Economy ticket for £123 per person are available. Travel duration is 11h 5m
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Volotea4h 15m020:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station00:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 26/12/2025 20:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/12/2025 00:20:00. 50 Economy ticket for £123 per person are available. Travel duration is 4h 15m
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EasyJet Airline14h 30m007:25Lyons St. Exupery AirportLyons St. Exupery Airport21:55Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 26/12/2025 07:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 21:55:00. 50 Economy ticket for £137 per person are available. Travel duration is 14h 30m
Cheapest Buses Friday
Cheapest Flights Friday
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 27/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 23:45:00. 50 Economy ticket for £48 per person are available. Travel duration is 14h 30m
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FlixBus14h 10m009:35LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 27/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 23:45:00. 50 Economy ticket for £61 per person are available. Travel duration is 14h 10m
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FlixBus14h 50m001:15LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 27/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 16:05:00. 50 Economy ticket for £70 per person are available. Travel duration is 14h 50m
Cheapest Buses Saturday
What are the fastest trips from Lyon to Rome?
You can get to Rome from Lyon in just 1h 35m with a Flight from Skyscanner. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 07:00:00. 50 Premium Economy ticket for £66 per person are available. Travel duration is 15h 30m
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FlixBus16h 0m018:00LyonPerrache Bus Stop10:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 18:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 10:00:00. 50 Economy ticket for £97 per person are available. Travel duration is 16h 0m
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FlixBus17h 30m012:35LyonPerrache Bus Stop06:05RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 12:35:00 to Anagnina Bus Station, Rome (Italy) arriving at 22/12/2025 06:05:00. 50 Economy ticket for £97 per person are available. Travel duration is 17h 30m
Fastest Buses Sunday
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Air France4h 15m018:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station22:45Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air France goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 22/12/2025 18:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/12/2025 22:45:00. 50 Economy ticket for £196 per person are available. Travel duration is 4h 15m
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Brussels Airlines5h 5m011:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station16:55Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Brussels Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 22/12/2025 11:50:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/12/2025 16:55:00. 50 Economy ticket for £193 per person are available. Travel duration is 5h 5m
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Volotea5h 50m009:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station15:45Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 22/12/2025 09:55:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 22/12/2025 15:45:00. 50 Economy ticket for £172 per person are available. Travel duration is 5h 50m
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LC Perú7h 25m008:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station16:00Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 22/12/2025 08:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 22/12/2025 16:00:00. 50 Economy ticket for £145 per person are available. Travel duration is 7h 25m
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FlixBus14h 10m009:35LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 22/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 23:45:00. 50 Economy ticket for £79 per person are available. Travel duration is 14h 10m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Coach Station0BasicA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 22/12/2025 15:30:00 to Tiburtina Coach Station, Rome (Italy) arriving at 23/12/2025 07:00:00. 50 Basic ticket for £48 per person are available. Travel duration is 15h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 22/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 07:00:00. 50 Premium Economy ticket for £54 per person are available. Travel duration is 15h 30m
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FlixBus16h 0m018:00LyonPerrache Bus Stop10:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 22/12/2025 18:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 10:00:00. 50 Economy ticket for £83 per person are available. Travel duration is 16h 0m
Fastest Flights Monday
Fastest Buses Monday
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Skyscanner1h 35m018:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/12/2025 18:50:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/12/2025 20:25:00. 50 Economy ticket for £120 per person are available. Travel duration is 1h 35m
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Volotea9h 55m006:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station16:25Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/12/2025 06:30:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/12/2025 16:25:00. 50 Economy ticket for £178 per person are available. Travel duration is 9h 55m
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EasyJet Airline10h 30m010:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:30Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/12/2025 10:00:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 23/12/2025 20:30:00. 50 Economy ticket for £158 per person are available. Travel duration is 10h 30m
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LC Perú13h 30m021:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station11:00Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/12/2025 21:30:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 24/12/2025 11:00:00. 50 Economy ticket for £268 per person are available. Travel duration is 13h 30m
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FlixBus14h 10m009:35LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 23/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/12/2025 23:45:00. 50 Economy ticket for £79 per person are available. Travel duration is 14h 10m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 23/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 07:00:00. 50 Premium Economy ticket for £48 per person are available. Travel duration is 15h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Coach Station0BasicA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 23/12/2025 15:30:00 to Tiburtina Coach Station, Rome (Italy) arriving at 24/12/2025 07:00:00. 50 Basic ticket for £50 per person are available. Travel duration is 15h 30m
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FlixBus15h 50m016:00LyonPerrache Bus Stop07:50RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 23/12/2025 16:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 07:50:00. 50 Economy ticket for £87 per person are available. Travel duration is 15h 50m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 24/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 23:45:00. 50 Premium Economy ticket for £48 per person are available. Travel duration is 14h 30m
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FlixBus14h 50m001:15LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 24/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/12/2025 16:05:00. 50 Economy ticket for £72 per person are available. Travel duration is 14h 50m
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FlixBus15h 30m020:45LyonPerrache Bus Stop12:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 24/12/2025 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 25/12/2025 12:15:00. 50 Economy ticket for £68 per person are available. Travel duration is 15h 30m
Fastest Buses Wednesday
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EasyJet Airline1h 35m012:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station14:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 25/12/2025 12:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 25/12/2025 14:15:00. 50 Economy ticket for £163 per person are available. Travel duration is 1h 35m
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Skyscanner1h 35m012:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station14:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 25/12/2025 12:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 25/12/2025 14:15:00. 50 Economy ticket for £164 per person are available. Travel duration is 1h 35m
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Vueling Airlines8h 40m008:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station16:55Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 25/12/2025 08:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 25/12/2025 16:55:00. 50 Economy ticket for £134 per person are available. Travel duration is 8h 40m
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Air Malta11h 45m020:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station07:45Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 25/12/2025 20:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 07:45:00. 50 Economy ticket for £85 per person are available. Travel duration is 11h 45m
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 25/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 23:45:00. 50 Premium Economy ticket for £49 per person are available. Travel duration is 14h 30m
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BlaBlaCar Bus14h 45m005:30LyonPerrache Bus Stop20:15RomeTiburtina Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Bus Stop, Lyon (France) at 25/12/2025 05:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 20:15:00. 50 Economy ticket for £48 per person are available. Travel duration is 14h 45m
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FlixBus14h 50m001:15LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 25/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/12/2025 16:05:00. 50 Economy ticket for £59 per person are available. Travel duration is 14h 50m
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FlixBus15h 30m020:45LyonPerrache Bus Stop12:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 25/12/2025 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 26/12/2025 12:15:00. 50 Economy ticket for £70 per person are available. Travel duration is 15h 30m
Fastest Flights Thursday
Fastest Buses Thursday
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Skyscanner1h 35m019:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:40Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 26/12/2025 19:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 20:40:00. 50 Economy ticket for £196 per person are available. Travel duration is 1h 35m
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Volotea4h 15m020:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station00:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 26/12/2025 20:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/12/2025 00:20:00. 50 Economy ticket for £123 per person are available. Travel duration is 4h 15m
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Vueling Airlines5h 25m018:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station23:30Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 26/12/2025 18:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/12/2025 23:30:00. 50 Economy ticket for £144 per person are available. Travel duration is 5h 25m
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LC Perú11h 5m008:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station19:40Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 26/12/2025 08:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 26/12/2025 19:40:00. 50 Economy ticket for £123 per person are available. Travel duration is 11h 5m
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BlaBlaCar Bus14h 45m005:30LyonPerrache Bus Stop20:15RomeTiburtina Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Bus Stop, Lyon (France) at 26/12/2025 05:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/12/2025 20:15:00. 50 Economy ticket for £48 per person are available. Travel duration is 14h 45m
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FlixBus14h 50m001:15LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 26/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/12/2025 16:05:00. 50 Economy ticket for £70 per person are available. Travel duration is 14h 50m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 26/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 07:00:00. 50 Premium Economy ticket for £48 per person are available. Travel duration is 15h 30m
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FlixBus15h 30m020:45LyonPerrache Bus Stop12:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 26/12/2025 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 27/12/2025 12:15:00. 50 Economy ticket for £82 per person are available. Travel duration is 15h 30m
Fastest Flights Friday
Fastest Buses Friday
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FlixBus14h 10m009:35LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 27/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 23:45:00. 50 Economy ticket for £61 per person are available. Travel duration is 14h 10m
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 27/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 23:45:00. 50 Economy ticket for £48 per person are available. Travel duration is 14h 30m
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FlixBus14h 50m001:15LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 27/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/12/2025 16:05:00. 50 Economy ticket for £70 per person are available. Travel duration is 14h 50m
Fastest Buses Saturday
Here you will find all operators and timetables for a
Bus from Lyon to Rome
What are the most popular stations in Lyon and Rome?
In Lyon, you will usually depart from Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, while in Rome you will be arriving at Termini Bus Station, Termini Central Station or Ostiense Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Rome from Lyon? With 10 connections between 4 Bus, Flight and Train operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Lyon and Rome, you can pay as low as £47 with a Bus from Itabus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Rome in just 1h 35m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Lyon and Rome are Itabus, FlixBus and Volotea, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Lyon and Rome is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Caluire-et-Cuire or to Settebagni, and look at flights from Lyons St. Exupery Airport, and landing at Rome Ciampino Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Lyon to Rome?
The most popular companies between Lyon and Rome, are Itabus, FlixBus and Volotea. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus, FlixBus and BlaBlaCar Bus
Airlines: Volotea, EasyJet Airline, LC Perú and 11 more.
All you need to know when you travel from Lyon to Rome
Check all information on comfort and services on all modes of transports from Lyon to Rome. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Lyon to Rome
How can I reach Rome from Lyon?
Every day, there are on average 10 connections between Bus, Flight and Train, with which you can get to Rome from Lyon.
How far is Rome from Lyon?
The distance between Lyon and Rome is 749.0 km.
What is the most ecofriendly mode of transport between Lyon and Rome?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 127 kgs, and a flight 184 kgs.
What is the cheapest mode of transport from Lyon to Rome?
You can get to Rome with just £47 by taking a Bus from Itabus.
What is the fastest way to get from Lyon to Rome?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Rome in just 1h 35m with a Flight from Skyscanner.
More routes to Lyon and to Rome
Looking for more options? Here you can see the most popular routes to Lyon and to Rome. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Lyon
- Alicante to Lyon
- Annecy to Lyon
- Avignon to Lyon
- Barcelona to Lyon
- Basel to Lyon
- Bologna to Lyon
- Bordeaux to Lyon
- Braga to Lyon
- Caen to Lyon
- Dusseldorf to Lyon
- Geneva to Lyon
- Genoa to Lyon
- Lille to Lyon
- Lisbon to Lyon
- London to Lyon
- Lyons St. Exupery Airport to Lyon
- Marseille to Lyon
- Milan to Lyon
- Paris to Lyon
- Rome to Lyon
- San Sebastian to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon
- Trips to Rome
- Alba Adriatica to Rome
- Avellino to Rome
- Bari to Rome
- Battipaglia to Rome
- Chieti to Rome
- Civitanova to Rome
- Crotone to Rome
- Fisciano to Rome
- Lamezia Terme to Rome
- Lecce to Rome
- Milan to Rome
- Mosciano Sant'Angelo to Rome
- Munich to Rome
- Naples to Rome
- Palermo to Rome
- Perugia to Rome
- Pescara to Rome
- Pisa to Rome
- Potenza to Rome
- Rome Fiumicino Airport to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Teramo to Rome
- Venice to Rome
