What is the best way to travel from Lyon to Rome?
Looking for a trip? Check and compare all the available Flights and Buses to Rome from Lyon. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Rome from Lyon?
You can reach Rome with just £26 by taking a Bus from Itabus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Coach Station0BasicA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 22/03/2026 09:15:00 to Tiburtina Coach Station, Rome (Italy) arriving at 22/03/2026 23:45:00. 50 Basic ticket for £36 per person are available. Travel duration is 14h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 22/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/03/2026 07:00:00. 50 Premium Economy ticket for £43 per person are available. Travel duration is 15h 30m
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FlixBus15h 30m020:45LyonLyon Avenue Tony Garnier Coach Stop12:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 22/03/2026 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 23/03/2026 12:15:00. 50 Economy ticket for £67 per person are available. Travel duration is 15h 30m
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FlixBus15h 40m008:05LyonLyon Avenue Tony Garnier Coach Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 22/03/2026 08:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/03/2026 23:45:00. 50 Economy ticket for £75 per person are available. Travel duration is 15h 40m
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Vueling Airlines24h 50m008:15Lyons St. Exupery AirportLyons St. Exupery Airport09:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 22/03/2026 08:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/03/2026 09:05:00. 50 Economy ticket for £98 per person are available. Travel duration is 24h 50m
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Volotea11h 20m020:05Lyons St. Exupery AirportLyons St. Exupery Airport07:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 22/03/2026 20:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/03/2026 07:25:00. 50 Economy ticket for £103 per person are available. Travel duration is 11h 20m
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EasyJet Airline1h 35m020:00Lyons St. Exupery AirportLyons St. Exupery Airport21:35Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 22/03/2026 20:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/03/2026 21:35:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 35m
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Lufthansa7h 55m014:55Lyons St. Exupery AirportLyons St. Exupery Airport22:50Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Lufthansa goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 22/03/2026 14:55:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/03/2026 22:50:00. 50 Economy ticket for £143 per person are available. Travel duration is 7h 55m
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Iberia12h 0m006:10Lyons St. Exupery AirportLyons St. Exupery Airport18:10Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Iberia goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 22/03/2026 06:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/03/2026 18:10:00. 50 Economy ticket for £189 per person are available. Travel duration is 12h 0m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 23/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 07:00:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 15h 30m
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FlixBus15h 30m020:45LyonLyon Avenue Tony Garnier Coach Stop12:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 24/03/2026 12:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 15h 30m
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Itabus14h 30m009:15LyonLyon Avenue Tony Garnier Coach Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/03/2026 23:45:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 14h 30m
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Itabus15h 30m015:30LyonLyon Avenue Tony Garnier Coach Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 07:00:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 15h 30m
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FlixBus17h 25m006:15LyonLyon Avenue Tony Garnier Coach Stop23:40RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 06:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/03/2026 23:40:00. 50 Economy ticket for £50 per person are available. Travel duration is 17h 25m
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EasyJet Airline25h 50m020:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station22:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/03/2026 20:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 24/03/2026 22:15:00. 50 Economy ticket for £74 per person are available. Travel duration is 25h 50m
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Vueling Airlines14h 50m020:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station11:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/03/2026 20:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 24/03/2026 11:05:00. 50 Economy ticket for £79 per person are available. Travel duration is 14h 50m
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Wizz Air28h 5m016:40Lyons St. Exupery AirportLyons St. Exupery Airport20:45Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 23/03/2026 16:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 24/03/2026 20:45:00. 50 Economy ticket for £79 per person are available. Travel duration is 28h 5m
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LC Perú5h 0m016:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/03/2026 16:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/03/2026 21:05:00. 50 Economy ticket for £88 per person are available. Travel duration is 5h 0m
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Brussels Airlines8h 25m011:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Brussels Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/03/2026 11:50:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/03/2026 20:15:00. 50 Economy ticket for £109 per person are available. Travel duration is 8h 25m
Cheapest Buses Monday
Cheapest Flights Monday
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FlixBus14h 50m001:15LyonLyon Avenue Tony Garnier Coach Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 16:05:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 50m
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Itabus15h 30m015:30LyonLyon Avenue Tony Garnier Coach Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 07:00:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 15h 30m
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 24/03/2026 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 23:45:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 14h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 24/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 07:00:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 15h 30m
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FlixBus14h 10m009:35LyonLyon Avenue Tony Garnier Coach Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 23:45:00. 50 Economy ticket for £39 per person are available. Travel duration is 14h 10m
Cheapest Buses Tuesday
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Itabus15h 30m015:30LyonLyon Avenue Tony Garnier Coach Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 25/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 07:00:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 15h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 25/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 07:00:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 15h 30m
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FlixBus17h 25m006:15LyonLyon Avenue Tony Garnier Coach Stop23:40RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 25/03/2026 06:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 23:40:00. 50 Economy ticket for £57 per person are available. Travel duration is 17h 25m
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FlixBus14h 50m001:15LyonLyon Avenue Tony Garnier Coach Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 25/03/2026 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 16:05:00. 50 Economy ticket for £60 per person are available. Travel duration is 14h 50m
Cheapest Buses Wednesday
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 26/03/2026 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 23:45:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 14h 30m
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FlixBus15h 30m020:45LyonLyon Avenue Tony Garnier Coach Stop12:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 27/03/2026 12:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 15h 30m
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Itabus14h 30m009:15LyonLyon Avenue Tony Garnier Coach Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 23:45:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 14h 30m
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Itabus15h 30m015:30LyonLyon Avenue Tony Garnier Coach Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 07:00:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 15h 30m
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FlixBus16h 50m012:45LyonLyon Avenue Tony Garnier Coach Stop05:35RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 12:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 05:35:00. 50 Economy ticket for £57 per person are available. Travel duration is 16h 50m
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EasyJet Airline7h 20m007:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station14:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 26/03/2026 07:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/03/2026 14:20:00. 50 Economy ticket for £59 per person are available. Travel duration is 7h 20m
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Skyscanner1h 35m019:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:10Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 26/03/2026 19:35:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/03/2026 21:10:00. 50 Economy ticket for £68 per person are available. Travel duration is 1h 35m
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Volotea8h 25m008:00Lyons St. Exupery AirportLyons St. Exupery Airport16:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 26/03/2026 08:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/03/2026 16:25:00. 50 Economy ticket for £103 per person are available. Travel duration is 8h 25m
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Wizz Air10h 45m014:30Lyons St. Exupery AirportLyons St. Exupery Airport01:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 26/03/2026 14:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/03/2026 01:15:00. 50 Economy ticket for £111 per person are available. Travel duration is 10h 45m
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Vueling Airlines8h 0m008:20Lyons St. Exupery AirportLyons St. Exupery Airport16:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 26/03/2026 08:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/03/2026 16:20:00. 50 Economy ticket for £132 per person are available. Travel duration is 8h 0m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 27/03/2026 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 23:45:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 14h 30m
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FlixBus14h 50m001:15LyonLyon Avenue Tony Garnier Coach Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 16:05:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 50m
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FlixBus14h 10m009:35LyonLyon Avenue Tony Garnier Coach Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 23:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 10m
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Itabus14h 30m009:15LyonLyon Avenue Tony Garnier Coach Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 23:45:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 14h 30m
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BlaBlaCar Bus14h 40m005:35LyonPerrache Train Station20:15RomeTiburtina Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 27/03/2026 05:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 20:15:00. 50 Economy ticket for £37 per person are available. Travel duration is 14h 40m
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EasyJet Airline8h 50m011:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 27/03/2026 11:35:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/03/2026 20:25:00. 50 Economy ticket for £63 per person are available. Travel duration is 8h 50m
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Skyscanner1h 30m007:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:30Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 27/03/2026 07:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/03/2026 08:30:00. 50 Economy ticket for £81 per person are available. Travel duration is 1h 30m
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Volotea16h 55m006:30Lyons St. Exupery AirportLyons St. Exupery Airport23:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 27/03/2026 06:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/03/2026 23:25:00. 50 Economy ticket for £90 per person are available. Travel duration is 16h 55m
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Wizz Air28h 5m016:40Lyons St. Exupery AirportLyons St. Exupery Airport20:45Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 27/03/2026 16:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 28/03/2026 20:45:00. 50 Economy ticket for £99 per person are available. Travel duration is 28h 5m
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LC Perú11h 0m010:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 27/03/2026 10:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/03/2026 21:05:00. 50 Economy ticket for £100 per person are available. Travel duration is 11h 0m
Cheapest Buses Friday
Cheapest Flights Friday
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 28/03/2026 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 28/03/2026 23:45:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 14h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop08:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 28/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 29/03/2026 08:00:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 15h 30m
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FlixBus14h 50m001:15LyonLyon Avenue Tony Garnier Coach Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 28/03/2026 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 28/03/2026 16:05:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 50m
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FlixBus14h 10m009:35LyonLyon Avenue Tony Garnier Coach Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 28/03/2026 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 28/03/2026 23:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 10m
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FlixBus15h 30m020:45LyonLyon Avenue Tony Garnier Coach Stop13:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 28/03/2026 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 29/03/2026 13:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 15h 30m
Cheapest Buses Saturday
What are the fastest trips from Lyon to Rome?
You can get to Rome from Lyon in just 1h 30m with a Flight from Skyscanner. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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EasyJet Airline1h 35m020:00Lyons St. Exupery AirportLyons St. Exupery Airport21:35Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 22/03/2026 20:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/03/2026 21:35:00. 50 Economy ticket for £106 per person are available. Travel duration is 1h 35m
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Lufthansa7h 55m014:55Lyons St. Exupery AirportLyons St. Exupery Airport22:50Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Lufthansa goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 22/03/2026 14:55:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/03/2026 22:50:00. 50 Economy ticket for £143 per person are available. Travel duration is 7h 55m
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Volotea11h 20m020:05Lyons St. Exupery AirportLyons St. Exupery Airport07:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 22/03/2026 20:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/03/2026 07:25:00. 50 Economy ticket for £103 per person are available. Travel duration is 11h 20m
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Iberia12h 0m006:10Lyons St. Exupery AirportLyons St. Exupery Airport18:10Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Iberia goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 22/03/2026 06:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 22/03/2026 18:10:00. 50 Economy ticket for £189 per person are available. Travel duration is 12h 0m
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Vueling Airlines24h 50m008:15Lyons St. Exupery AirportLyons St. Exupery Airport09:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 22/03/2026 08:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/03/2026 09:05:00. 50 Economy ticket for £98 per person are available. Travel duration is 24h 50m
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Coach Station0BasicA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 22/03/2026 09:15:00 to Tiburtina Coach Station, Rome (Italy) arriving at 22/03/2026 23:45:00. 50 Basic ticket for £36 per person are available. Travel duration is 14h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 22/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/03/2026 07:00:00. 50 Premium Economy ticket for £43 per person are available. Travel duration is 15h 30m
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FlixBus15h 30m020:45LyonLyon Avenue Tony Garnier Coach Stop12:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 22/03/2026 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 23/03/2026 12:15:00. 50 Economy ticket for £67 per person are available. Travel duration is 15h 30m
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FlixBus15h 40m008:05LyonLyon Avenue Tony Garnier Coach Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 22/03/2026 08:05:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/03/2026 23:45:00. 50 Economy ticket for £75 per person are available. Travel duration is 15h 40m
Fastest Flights Sunday
Fastest Buses Sunday
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LC Perú5h 0m016:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/03/2026 16:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/03/2026 21:05:00. 50 Economy ticket for £88 per person are available. Travel duration is 5h 0m
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Brussels Airlines8h 25m011:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Brussels Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/03/2026 11:50:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 23/03/2026 20:15:00. 50 Economy ticket for £109 per person are available. Travel duration is 8h 25m
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Vueling Airlines14h 50m020:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station11:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/03/2026 20:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 24/03/2026 11:05:00. 50 Economy ticket for £79 per person are available. Travel duration is 14h 50m
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EasyJet Airline25h 50m020:25Lyons St. Exupery AirportAéroport St Exupéry Coach Station22:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 23/03/2026 20:25:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 24/03/2026 22:15:00. 50 Economy ticket for £74 per person are available. Travel duration is 25h 50m
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Wizz Air28h 5m016:40Lyons St. Exupery AirportLyons St. Exupery Airport20:45Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 23/03/2026 16:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 24/03/2026 20:45:00. 50 Economy ticket for £79 per person are available. Travel duration is 28h 5m
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Itabus14h 30m009:15LyonLyon Avenue Tony Garnier Coach Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/03/2026 23:45:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 14h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 23/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 07:00:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 15h 30m
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FlixBus15h 30m020:45LyonLyon Avenue Tony Garnier Coach Stop12:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 24/03/2026 12:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 15h 30m
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Itabus15h 30m015:30LyonLyon Avenue Tony Garnier Coach Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 07:00:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 15h 30m
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FlixBus17h 25m006:15LyonLyon Avenue Tony Garnier Coach Stop23:40RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 23/03/2026 06:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 23/03/2026 23:40:00. 50 Economy ticket for £50 per person are available. Travel duration is 17h 25m
Fastest Flights Monday
Fastest Buses Monday
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FlixBus14h 10m009:35LyonLyon Avenue Tony Garnier Coach Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 23:45:00. 50 Economy ticket for £39 per person are available. Travel duration is 14h 10m
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 24/03/2026 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 23:45:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 14h 30m
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FlixBus14h 50m001:15LyonLyon Avenue Tony Garnier Coach Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 24/03/2026 16:05:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 50m
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Itabus15h 30m015:30LyonLyon Avenue Tony Garnier Coach Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 24/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 07:00:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 15h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 24/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 07:00:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 15h 30m
Fastest Buses Tuesday
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FlixBus14h 50m001:15LyonLyon Avenue Tony Garnier Coach Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 25/03/2026 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 16:05:00. 50 Economy ticket for £60 per person are available. Travel duration is 14h 50m
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Itabus15h 30m015:30LyonLyon Avenue Tony Garnier Coach Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 25/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 07:00:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 15h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 25/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 07:00:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 15h 30m
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FlixBus17h 25m006:15LyonLyon Avenue Tony Garnier Coach Stop23:40RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 25/03/2026 06:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 25/03/2026 23:40:00. 50 Economy ticket for £57 per person are available. Travel duration is 17h 25m
Fastest Buses Wednesday
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Skyscanner1h 35m019:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:10Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 26/03/2026 19:35:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/03/2026 21:10:00. 50 Economy ticket for £68 per person are available. Travel duration is 1h 35m
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EasyJet Airline7h 20m007:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station14:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 26/03/2026 07:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/03/2026 14:20:00. 50 Economy ticket for £59 per person are available. Travel duration is 7h 20m
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Vueling Airlines8h 0m008:20Lyons St. Exupery AirportLyons St. Exupery Airport16:20Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 26/03/2026 08:20:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/03/2026 16:20:00. 50 Economy ticket for £132 per person are available. Travel duration is 8h 0m
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Volotea8h 25m008:00Lyons St. Exupery AirportLyons St. Exupery Airport16:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 26/03/2026 08:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 26/03/2026 16:25:00. 50 Economy ticket for £103 per person are available. Travel duration is 8h 25m
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Wizz Air10h 45m014:30Lyons St. Exupery AirportLyons St. Exupery Airport01:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 26/03/2026 14:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/03/2026 01:15:00. 50 Economy ticket for £111 per person are available. Travel duration is 10h 45m
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 26/03/2026 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 23:45:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 14h 30m
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Itabus14h 30m009:15LyonLyon Avenue Tony Garnier Coach Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 26/03/2026 23:45:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 14h 30m
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FlixBus15h 30m020:45LyonLyon Avenue Tony Garnier Coach Stop12:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 27/03/2026 12:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 15h 30m
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Itabus15h 30m015:30LyonLyon Avenue Tony Garnier Coach Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 07:00:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 15h 30m
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FlixBus16h 50m012:45LyonLyon Avenue Tony Garnier Coach Stop05:35RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 26/03/2026 12:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 05:35:00. 50 Economy ticket for £57 per person are available. Travel duration is 16h 50m
Fastest Flights Thursday
Fastest Buses Thursday
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Skyscanner1h 30m007:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:30Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 27/03/2026 07:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/03/2026 08:30:00. 50 Economy ticket for £81 per person are available. Travel duration is 1h 30m
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EasyJet Airline8h 50m011:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 27/03/2026 11:35:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/03/2026 20:25:00. 50 Economy ticket for £63 per person are available. Travel duration is 8h 50m
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LC Perú11h 0m010:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 27/03/2026 10:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/03/2026 21:05:00. 50 Economy ticket for £100 per person are available. Travel duration is 11h 0m
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Volotea16h 55m006:30Lyons St. Exupery AirportLyons St. Exupery Airport23:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Volotea goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 27/03/2026 06:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 27/03/2026 23:25:00. 50 Economy ticket for £90 per person are available. Travel duration is 16h 55m
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Wizz Air28h 5m016:40Lyons St. Exupery AirportLyons St. Exupery Airport20:45Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Wizz Air goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 27/03/2026 16:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 28/03/2026 20:45:00. 50 Economy ticket for £99 per person are available. Travel duration is 28h 5m
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FlixBus14h 10m009:35LyonLyon Avenue Tony Garnier Coach Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 23:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 10m
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 27/03/2026 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 23:45:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 14h 30m
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Itabus14h 30m009:15LyonLyon Avenue Tony Garnier Coach Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 23:45:00. 50 Premium Economy ticket for £31 per person are available. Travel duration is 14h 30m
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BlaBlaCar Bus14h 40m005:35LyonPerrache Train Station20:15RomeTiburtina Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Perrache Train Station, Lyon (France) at 27/03/2026 05:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 20:15:00. 50 Economy ticket for £37 per person are available. Travel duration is 14h 40m
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FlixBus14h 50m001:15LyonLyon Avenue Tony Garnier Coach Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 27/03/2026 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 27/03/2026 16:05:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 50m
Fastest Flights Friday
Fastest Buses Friday
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FlixBus14h 10m009:35LyonLyon Avenue Tony Garnier Coach Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 28/03/2026 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 28/03/2026 23:45:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 10m
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 28/03/2026 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 28/03/2026 23:45:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 14h 30m
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FlixBus14h 50m001:15LyonLyon Avenue Tony Garnier Coach Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 28/03/2026 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 28/03/2026 16:05:00. 50 Economy ticket for £31 per person are available. Travel duration is 14h 50m
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Itabus15h 30m015:30LyonPerrache Bus Stop08:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 28/03/2026 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 29/03/2026 08:00:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 15h 30m
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FlixBus15h 30m020:45LyonLyon Avenue Tony Garnier Coach Stop13:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Lyon Avenue Tony Garnier Coach Stop, Lyon (France) at 28/03/2026 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 29/03/2026 13:15:00. 50 Economy ticket for £31 per person are available. Travel duration is 15h 30m
Fastest Buses Saturday
Here you will find all operators and timetables for a
Bus from Lyon to Rome
What are the most popular stations in Lyon and Rome?
In Lyon, you will usually depart from Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, while in Rome you will be arriving at Termini Bus Station, Ostiense Train Station or Termini Central Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Rome from Lyon? With 7 connections between 3 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Lyon and Rome, you can pay as low as £26 with a Bus from Itabus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Rome in just 1h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Lyon and Rome are Itabus, FlixBus and EasyJet Airline, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Lyon and Rome is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Caluire-et-Cuire or to Settebagni, and look at flights from Lyons St. Exupery Airport, and landing at Rome Ciampino Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Lyon to Rome?
The most popular companies between Lyon and Rome, are Itabus, FlixBus and EasyJet Airline. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus, FlixBus and BlaBlaCar Bus
Airlines: EasyJet Airline, Vueling Airlines, Volotea and 6 more.
All you need to know when you travel from Lyon to Rome
Check all information on comfort and services on all modes of transports from Lyon to Rome. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Lyon to Rome
How can I reach Rome from Lyon?
Every day, there are on average 7 connections between Flight and Bus, with which you can get to Rome from Lyon.
How far is Rome from Lyon?
The distance between Lyon and Rome is 749.0 km.
What is the most ecofriendly mode of transport between Lyon and Rome?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 127 kgs, and a flight 184 kgs.
What is the cheapest mode of transport from Lyon to Rome?
You can get to Rome with just £26 by taking a Bus from Itabus.
What is the fastest way to get from Lyon to Rome?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Rome in just 1h 30m with a Flight from Skyscanner.
More routes to Lyon and to Rome
Looking for more options? Here you can see the most popular routes to Lyon and to Rome. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Lyon
- Alicante to Lyon
- Annecy to Lyon
- Avignon to Lyon
- Barcelona to Lyon
- Birmingham to Lyon
- Bordeaux to Lyon
- Dusseldorf to Lyon
- Geneva to Lyon
- Genoa to Lyon
- Grenoble to Lyon
- Lille to Lyon
- London to Lyon
- Madrid to Lyon
- Marseille to Lyon
- Milan to Lyon
- Nantes to Lyon
- Nice to Lyon
- Paris Orly Airport to Lyon
- Paris to Lyon
- Rome to Lyon
- Saint-Étienne to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon
- Trips to Rome
- Bari to Rome
- Caserta to Rome
- Cassino to Rome
- Catania to Rome
- Catanzaro to Rome
- Civitanova to Rome
- Grottaminarda to Rome
- L'Aquila to Rome
- Lanciano to Rome
- Lecce to Rome
- Marseille to Rome
- Milan to Rome
- Mosciano Sant'Angelo to Rome
- Naples to Rome
- Nocera Inferiore to Rome
- Palermo to Rome
- Perugia to Rome
- Porto D'Ascoli to Rome
- Porto San Giorgio to Rome
- Potenza to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
