What is the best way to travel from Lyon to Rome?
Looking for a trip? Check and compare all the available Buses and Flights to Rome from Lyon. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Rome from Lyon?
You can reach Rome with just £30 by taking a Bus from Itabus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 15/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 15/12/2025 23:45:00. 50 Economy ticket for £34 per person are available. Travel duration is 14h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 15/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 16/12/2025 07:00:00. 50 Economy ticket for £34 per person are available. Travel duration is 15h 30m
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FlixBus14h 10m009:35LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 15/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 15/12/2025 23:45:00. 50 Economy ticket for £39 per person are available. Travel duration is 14h 10m
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FlixBus15h 30m020:45LyonPerrache Bus Stop12:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 15/12/2025 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 16/12/2025 12:15:00. 50 Economy ticket for £39 per person are available. Travel duration is 15h 30m
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STARSHIPPER SAS17h 40m014:10Lyons St. Exupery AirportLyons St. Exupery Airport07:50RomeTiburtina Bus Station0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 15/12/2025 14:10:00 to Tiburtina Bus Station, Rome (Italy) arriving at 16/12/2025 07:50:00. 50 Economy ticket for £55 per person are available. Travel duration is 17h 40m
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EasyJet Airline1h 30m007:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:35Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 15/12/2025 07:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 15/12/2025 08:35:00. 50 Economy ticket for £39 per person are available. Travel duration is 1h 30m
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LC Perú12h 30m008:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 15/12/2025 08:35:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 15/12/2025 21:05:00. 50 Economy ticket for £58 per person are available. Travel duration is 12h 30m
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LC Perú7h 25m008:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station16:00Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 15/12/2025 08:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 15/12/2025 16:00:00. 50 Economy ticket for £60 per person are available. Travel duration is 7h 25m
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Vueling Airlines4h 35m020:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station00:50Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 15/12/2025 20:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 16/12/2025 00:50:00. 50 Economy ticket for £63 per person are available. Travel duration is 4h 35m
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Air Nostrum13h 20m006:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station19:30Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Nostrum goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 15/12/2025 06:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 15/12/2025 19:30:00. 50 Economy ticket for £73 per person are available. Travel duration is 13h 20m
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KLM - Royal Dutch Airlines5h 15m014:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station19:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from KLM - Royal Dutch Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 15/12/2025 14:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 15/12/2025 19:25:00. 50 Economy ticket for £175 per person are available. Travel duration is 5h 15m
Cheapest Buses Monday
Cheapest Flights Monday
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 16/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 16/12/2025 23:45:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 14h 30m
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FlixBus14h 10m009:35LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 16/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 16/12/2025 23:45:00. 50 Economy ticket for £39 per person are available. Travel duration is 14h 10m
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FlixBus14h 50m001:15LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 16/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 16/12/2025 16:05:00. 50 Economy ticket for £57 per person are available. Travel duration is 14h 50m
Cheapest Buses Tuesday
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 17/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 17/12/2025 23:45:00. 50 Premium Economy ticket for £39 per person are available. Travel duration is 14h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 17/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/12/2025 07:00:00. 50 Premium Economy ticket for £58 per person are available. Travel duration is 15h 30m
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FlixBus14h 50m001:15LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 17/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 17/12/2025 16:05:00. 50 Economy ticket for £61 per person are available. Travel duration is 14h 50m
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FlixBus16h 0m018:00LyonPerrache Bus Stop10:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 17/12/2025 18:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/12/2025 10:00:00. 50 Economy ticket for £68 per person are available. Travel duration is 16h 0m
Cheapest Buses Wednesday
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 18/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/12/2025 23:45:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 14h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 18/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 07:00:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 15h 30m
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FlixBus16h 35m020:45LyonPerrache Bus Stop13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 18/12/2025 20:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 13:20:00. 50 Economy ticket for £79 per person are available. Travel duration is 16h 35m
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FlixBus17h 5m023:00LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 18/12/2025 23:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 16:05:00. 50 Economy ticket for £79 per person are available. Travel duration is 17h 5m
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EasyJet Airline1h 35m019:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:10Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 18/12/2025 19:35:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 18/12/2025 21:10:00. 50 Economy ticket for £53 per person are available. Travel duration is 1h 35m
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Skyscanner1h 35m019:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:10Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 18/12/2025 19:35:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 18/12/2025 21:10:00. 50 Economy ticket for £55 per person are available. Travel duration is 1h 35m
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LC Perú5h 25m008:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station14:00Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 18/12/2025 08:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 18/12/2025 14:00:00. 50 Economy ticket for £89 per person are available. Travel duration is 5h 25m
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Air Malta10h 15m021:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station07:45Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 18/12/2025 21:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 19/12/2025 07:45:00. 50 Economy ticket for £97 per person are available. Travel duration is 10h 15m
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Vueling Airlines5h 45m008:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station14:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 18/12/2025 08:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 18/12/2025 14:00:00. 50 Economy ticket for £141 per person are available. Travel duration is 5h 45m
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Hop!5h 20m017:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station23:10Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Hop! goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 18/12/2025 17:50:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 18/12/2025 23:10:00. 50 Economy ticket for £222 per person are available. Travel duration is 5h 20m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 19/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 20/12/2025 07:00:00. 50 Premium Economy ticket for £44 per person are available. Travel duration is 15h 30m
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FlixBus14h 50m001:15LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 19/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 16:05:00. 50 Economy ticket for £66 per person are available. Travel duration is 14h 50m
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FlixBus16h 45m001:15LyonPerrache Bus Stop18:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 19/12/2025 01:15:00 to Anagnina Bus Station, Rome (Italy) arriving at 19/12/2025 18:00:00. 50 Economy ticket for £83 per person are available. Travel duration is 16h 45m
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STARSHIPPER SAS21h 40m014:10Lyons St. Exupery AirportLyons St. Exupery Airport11:50RomeTiburtina Bus Station0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 19/12/2025 14:10:00 to Tiburtina Bus Station, Rome (Italy) arriving at 20/12/2025 11:50:00. 50 Economy ticket for £137 per person are available. Travel duration is 21h 40m
Cheapest Buses Friday
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 20/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 20/12/2025 23:45:00. 50 Premium Economy ticket for £51 per person are available. Travel duration is 14h 30m
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Itabus19h 50m023:50LyonPerrache Bus Stop19:40RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 20/12/2025 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 19:40:00. 50 Premium Economy ticket for £54 per person are available. Travel duration is 19h 50m
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FlixBus16h 5m014:55LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 20/12/2025 14:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 07:00:00. 50 Economy ticket for £74 per person are available. Travel duration is 16h 5m
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FlixBus15h 50m016:00LyonPerrache Bus Stop07:50RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 20/12/2025 16:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 07:50:00. 50 Economy ticket for £83 per person are available. Travel duration is 15h 50m
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Volotea7h 10m014:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:20Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 20/12/2025 14:10:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 20/12/2025 21:20:00. 50 Economy ticket for £168 per person are available. Travel duration is 7h 10m
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Vueling Airlines6h 10m008:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station14:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 20/12/2025 08:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 20/12/2025 14:25:00. 50 Economy ticket for £206 per person are available. Travel duration is 6h 10m
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EasyJet Airline4h 30m008:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station12:30Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 20/12/2025 08:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 20/12/2025 12:30:00. 50 Economy ticket for £264 per person are available. Travel duration is 4h 30m
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Skyscanner1h 35m012:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station14:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 20/12/2025 12:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 20/12/2025 14:15:00. 50 Economy ticket for £289 per person are available. Travel duration is 1h 35m
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Aer Lingus17h 30m017:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station10:40Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Aer Lingus goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 20/12/2025 17:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 21/12/2025 10:40:00. 50 Economy ticket for £303 per person are available. Travel duration is 17h 30m
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British Airways13h 40m021:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station11:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from British Airways goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 20/12/2025 21:45:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 21/12/2025 11:25:00. 50 Economy ticket for £312 per person are available. Travel duration is 13h 40m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 07:00:00. 50 Premium Economy ticket for £47 per person are available. Travel duration is 15h 30m
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 23:45:00. 50 Premium Economy ticket for £51 per person are available. Travel duration is 14h 30m
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FlixBus14h 10m009:35LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 23:45:00. 50 Economy ticket for £86 per person are available. Travel duration is 14h 10m
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FlixBus16h 0m018:00LyonPerrache Bus Stop10:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 18:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 10:00:00. 50 Economy ticket for £91 per person are available. Travel duration is 16h 0m
Cheapest Buses Sunday
What are the fastest trips from Lyon to Rome?
You can get to Rome from Lyon in just 1h 30m with a Flight from EasyJet Airline. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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EasyJet Airline1h 30m007:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:35Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 15/12/2025 07:05:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 15/12/2025 08:35:00. 50 Economy ticket for £39 per person are available. Travel duration is 1h 30m
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Vueling Airlines4h 35m020:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station00:50Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 15/12/2025 20:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 16/12/2025 00:50:00. 50 Economy ticket for £63 per person are available. Travel duration is 4h 35m
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KLM - Royal Dutch Airlines5h 15m014:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station19:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from KLM - Royal Dutch Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 15/12/2025 14:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 15/12/2025 19:25:00. 50 Economy ticket for £175 per person are available. Travel duration is 5h 15m
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LC Perú7h 25m008:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station16:00Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 15/12/2025 08:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 15/12/2025 16:00:00. 50 Economy ticket for £60 per person are available. Travel duration is 7h 25m
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LC Perú12h 30m008:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:05Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 15/12/2025 08:35:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 15/12/2025 21:05:00. 50 Economy ticket for £58 per person are available. Travel duration is 12h 30m
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Air Nostrum13h 20m006:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station19:30Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Nostrum goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 15/12/2025 06:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 15/12/2025 19:30:00. 50 Economy ticket for £73 per person are available. Travel duration is 13h 20m
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FlixBus14h 10m009:35LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 15/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 15/12/2025 23:45:00. 50 Economy ticket for £39 per person are available. Travel duration is 14h 10m
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 15/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 15/12/2025 23:45:00. 50 Economy ticket for £34 per person are available. Travel duration is 14h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 15/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 16/12/2025 07:00:00. 50 Economy ticket for £34 per person are available. Travel duration is 15h 30m
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FlixBus15h 30m020:45LyonPerrache Bus Stop12:15RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 15/12/2025 20:45:00 to Anagnina Bus Station, Rome (Italy) arriving at 16/12/2025 12:15:00. 50 Economy ticket for £39 per person are available. Travel duration is 15h 30m
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STARSHIPPER SAS17h 40m014:10Lyons St. Exupery AirportLyons St. Exupery Airport07:50RomeTiburtina Bus Station0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 15/12/2025 14:10:00 to Tiburtina Bus Station, Rome (Italy) arriving at 16/12/2025 07:50:00. 50 Economy ticket for £55 per person are available. Travel duration is 17h 40m
Fastest Flights Monday
Fastest Buses Monday
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FlixBus14h 10m009:35LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 16/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 16/12/2025 23:45:00. 50 Economy ticket for £39 per person are available. Travel duration is 14h 10m
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 16/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 16/12/2025 23:45:00. 50 Premium Economy ticket for £34 per person are available. Travel duration is 14h 30m
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FlixBus14h 50m001:15LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 16/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 16/12/2025 16:05:00. 50 Economy ticket for £57 per person are available. Travel duration is 14h 50m
Fastest Buses Tuesday
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 17/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 17/12/2025 23:45:00. 50 Premium Economy ticket for £39 per person are available. Travel duration is 14h 30m
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FlixBus14h 50m001:15LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 17/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 17/12/2025 16:05:00. 50 Economy ticket for £61 per person are available. Travel duration is 14h 50m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 17/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/12/2025 07:00:00. 50 Premium Economy ticket for £58 per person are available. Travel duration is 15h 30m
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FlixBus16h 0m018:00LyonPerrache Bus Stop10:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 17/12/2025 18:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/12/2025 10:00:00. 50 Economy ticket for £68 per person are available. Travel duration is 16h 0m
Fastest Buses Wednesday
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EasyJet Airline1h 35m019:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:10Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 18/12/2025 19:35:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 18/12/2025 21:10:00. 50 Economy ticket for £53 per person are available. Travel duration is 1h 35m
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Skyscanner1h 35m019:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:10Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 18/12/2025 19:35:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 18/12/2025 21:10:00. 50 Economy ticket for £55 per person are available. Travel duration is 1h 35m
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Hop!5h 20m017:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station23:10Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Hop! goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 18/12/2025 17:50:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 18/12/2025 23:10:00. 50 Economy ticket for £222 per person are available. Travel duration is 5h 20m
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LC Perú5h 25m008:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station14:00Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from LC Perú goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 18/12/2025 08:35:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 18/12/2025 14:00:00. 50 Economy ticket for £89 per person are available. Travel duration is 5h 25m
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Vueling Airlines5h 45m008:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station14:00Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 18/12/2025 08:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 18/12/2025 14:00:00. 50 Economy ticket for £141 per person are available. Travel duration is 5h 45m
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Air Malta10h 15m021:30Lyons St. Exupery AirportAéroport St Exupéry Coach Station07:45Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Air Malta goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 18/12/2025 21:30:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 19/12/2025 07:45:00. 50 Economy ticket for £97 per person are available. Travel duration is 10h 15m
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 18/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 18/12/2025 23:45:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 14h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 18/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 07:00:00. 50 Premium Economy ticket for £30 per person are available. Travel duration is 15h 30m
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FlixBus16h 35m020:45LyonPerrache Bus Stop13:20RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 18/12/2025 20:45:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 13:20:00. 50 Economy ticket for £79 per person are available. Travel duration is 16h 35m
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FlixBus17h 5m023:00LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 18/12/2025 23:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 16:05:00. 50 Economy ticket for £79 per person are available. Travel duration is 17h 5m
Fastest Flights Thursday
Fastest Buses Thursday
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FlixBus14h 50m001:15LyonPerrache Bus Stop16:05RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 19/12/2025 01:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 19/12/2025 16:05:00. 50 Economy ticket for £66 per person are available. Travel duration is 14h 50m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 19/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 20/12/2025 07:00:00. 50 Premium Economy ticket for £44 per person are available. Travel duration is 15h 30m
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FlixBus16h 45m001:15LyonPerrache Bus Stop18:00RomeAnagnina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 19/12/2025 01:15:00 to Anagnina Bus Station, Rome (Italy) arriving at 19/12/2025 18:00:00. 50 Economy ticket for £83 per person are available. Travel duration is 16h 45m
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STARSHIPPER SAS21h 40m014:10Lyons St. Exupery AirportLyons St. Exupery Airport11:50RomeTiburtina Bus Station0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 19/12/2025 14:10:00 to Tiburtina Bus Station, Rome (Italy) arriving at 20/12/2025 11:50:00. 50 Economy ticket for £137 per person are available. Travel duration is 21h 40m
Fastest Buses Friday
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Skyscanner1h 35m012:40Lyons St. Exupery AirportAéroport St Exupéry Coach Station14:15Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Skyscanner goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 20/12/2025 12:40:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 20/12/2025 14:15:00. 50 Economy ticket for £289 per person are available. Travel duration is 1h 35m
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EasyJet Airline4h 30m008:00Lyons St. Exupery AirportAéroport St Exupéry Coach Station12:30Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 20/12/2025 08:00:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 20/12/2025 12:30:00. 50 Economy ticket for £264 per person are available. Travel duration is 4h 30m
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Vueling Airlines6h 10m008:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station14:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 20/12/2025 08:15:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 20/12/2025 14:25:00. 50 Economy ticket for £206 per person are available. Travel duration is 6h 10m
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Volotea7h 10m014:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station21:20Rome Ciampino AirportRome Ciampino Airport0EconomyA Flight from Volotea goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 20/12/2025 14:10:00 to Rome Ciampino Airport, Rome Ciampino Airport (Italy) arriving at 20/12/2025 21:20:00. 50 Economy ticket for £168 per person are available. Travel duration is 7h 10m
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British Airways13h 40m021:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station11:25Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from British Airways goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 20/12/2025 21:45:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 21/12/2025 11:25:00. 50 Economy ticket for £312 per person are available. Travel duration is 13h 40m
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Aer Lingus17h 30m017:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station10:40Rome Fiumicino AirportRome Fiumicino Airport0EconomyA Flight from Aer Lingus goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 20/12/2025 17:10:00 to Rome Fiumicino Airport, Rome Fiumicino Airport (Italy) arriving at 21/12/2025 10:40:00. 50 Economy ticket for £303 per person are available. Travel duration is 17h 30m
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 20/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 20/12/2025 23:45:00. 50 Premium Economy ticket for £51 per person are available. Travel duration is 14h 30m
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FlixBus15h 50m016:00LyonPerrache Bus Stop07:50RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 20/12/2025 16:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 07:50:00. 50 Economy ticket for £83 per person are available. Travel duration is 15h 50m
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FlixBus16h 5m014:55LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 20/12/2025 14:55:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 07:00:00. 50 Economy ticket for £74 per person are available. Travel duration is 16h 5m
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Itabus19h 50m023:50LyonPerrache Bus Stop19:40RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 20/12/2025 23:50:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 19:40:00. 50 Premium Economy ticket for £54 per person are available. Travel duration is 19h 50m
Fastest Flights Saturday
Fastest Buses Saturday
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FlixBus14h 10m009:35LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 09:35:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 23:45:00. 50 Economy ticket for £86 per person are available. Travel duration is 14h 10m
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Itabus14h 30m009:15LyonPerrache Bus Stop23:45RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 09:15:00 to Tiburtina Bus Station, Rome (Italy) arriving at 21/12/2025 23:45:00. 50 Premium Economy ticket for £51 per person are available. Travel duration is 14h 30m
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Itabus15h 30m015:30LyonPerrache Bus Stop07:00RomeTiburtina Bus Station0Premium EconomyA Bus from Itabus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 15:30:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 07:00:00. 50 Premium Economy ticket for £47 per person are available. Travel duration is 15h 30m
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FlixBus16h 0m018:00LyonPerrache Bus Stop10:00RomeTiburtina Bus Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 21/12/2025 18:00:00 to Tiburtina Bus Station, Rome (Italy) arriving at 22/12/2025 10:00:00. 50 Economy ticket for £91 per person are available. Travel duration is 16h 0m
Fastest Buses Sunday
Here you will find all operators and timetables for a
Bus from Lyon to Rome
What are the most popular stations in Lyon and Rome?
In Lyon, you will usually depart from Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, while in Rome you will be arriving at Termini Bus Station, Termini Central Station or Ostiense Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Rome from Lyon? With 7 connections between 3 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Lyon and Rome, you can pay as low as £30 with a Bus from Itabus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from EasyJet Airline: you will get to Rome in just 1h 30m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Lyon and Rome are Itabus, FlixBus and LC Perú, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Lyon and Rome is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Caluire-et-Cuire or to Settebagni, and look at flights from Lyons St. Exupery Airport, and landing at Rome Ciampino Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Lyon to Rome?
The most popular companies between Lyon and Rome, are Itabus, FlixBus and LC Perú. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Itabus, FlixBus and STARSHIPPER SAS
Airlines: LC Perú, EasyJet Airline, Vueling Airlines and 8 more.
All you need to know when you travel from Lyon to Rome
Check all information on comfort and services on all modes of transports from Lyon to Rome. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Lyon to Rome
How can I reach Rome from Lyon?
Every day, there are on average 7 connections between Bus and Flight, with which you can get to Rome from Lyon.
How far is Rome from Lyon?
The distance between Lyon and Rome is 749.0 km.
What is the most ecofriendly mode of transport between Lyon and Rome?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 127 kgs, and a flight 184 kgs.
What is the cheapest mode of transport from Lyon to Rome?
You can get to Rome with just £30 by taking a Bus from Itabus.
What is the fastest way to get from Lyon to Rome?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Rome in just 1h 30m with a Flight from EasyJet Airline.
More routes to Lyon and to Rome
Looking for more options? Here you can see the most popular routes to Lyon and to Rome. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Lyon
- Alicante to Lyon
- Annecy to Lyon
- Barcelona to Lyon
- Bern to Lyon
- Bologna to Lyon
- Bordeaux to Lyon
- Braga to Lyon
- Caen to Lyon
- Dijon to Lyon
- Dusseldorf to Lyon
- Geneva to Lyon
- Genoa to Lyon
- Grenoble to Lyon
- Lisbon to Lyon
- Lloret de Mar to Lyon
- London to Lyon
- Lyons St. Exupery Airport to Lyon
- Marseille to Lyon
- Milan to Lyon
- Paris to Lyon
- Rome to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon
- Trips to Rome
- Avellino to Rome
- Bari to Rome
- Battipaglia to Rome
- Catanzaro to Rome
- Chieti to Rome
- Civitanova to Rome
- Foggia to Rome
- Genoa to Rome
- L'Aquila to Rome
- Lamezia Terme to Rome
- Lecce to Rome
- Milan to Rome
- Mosciano Sant'Angelo to Rome
- Naples to Rome
- Palermo to Rome
- Perugia to Rome
- Pescara to Rome
- Porto D'Ascoli to Rome
- Potenza to Rome
- Rome Fiumicino Airport to Rome
- Sala Consilina to Rome
- Salerno to Rome
- San Benedetto del Tronto to Rome
- Venice to Rome

