Which bus from Lyon to Prague is the cheapest?

Compare all coach companies and find the best price: Bus tickets from £41
Search for your destination Millions of deals worldwide
Compare results Save up to 70%
Find the right bus for you Easy and transparent

Which bus from Lyon to Prague is the best?

Check the bus schedule for Lyon to Prague. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus, BlaBlaCar Bus or RegioJet. To see the full timetable for all coaches just use or search and compare.

today
£64
tomorrow
£51
Tuesday
£48
Wednesday
£50
Thursday
£44
Friday
£47
Saturday
£48

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 17h 5m 21:30 Lyon Lyon Avenue Tony Garnier Coach Stop 14:35 Prague Wilsonova Coach Station  Economy £64
FlixBus 17h 15m 21:30 Lyon Lyon Avenue Tony Garnier Coach Stop 14:45 Prague ÚAN Florenc  Economy £64
FlixBus 15h 15m 18:05 Lyon Lyon Avenue Tony Garnier Coach Stop 09:20 Prague ÚAN Florenc  Economy £69
FlixBus 14h 50m 18:05 Lyon Lyon Avenue Tony Garnier Coach Stop 08:55 Prague Na Knížecí Station  Economy £69
FlixBus 17h 25m 22:00 Lyon Lyon Avenue Tony Garnier Coach Stop 15:25 Prague ÚAN Florenc  Economy £70
  • Did you know that if you travel from Lyon to Prague via Bern, you can save more than £15? You can find the corresponding connections below.
    • FlixBus
      17h 5m
      0
      16:15
      Lyon
      Lyon Avenue Tony Garnier Coach Stop
      22:05
      Bern
      Bern Car Terminal Neufeld
      0
      FlixBus
      Economy
      £18
      • Waiting Time 0h 20m
    • FlixBus
      10h 55m
      0
      22:25
      Bern
      Bern Car Terminal Neufeld
      09:20
      Prague
      ÚAN Florenc
      0
      FlixBus
      Economy
      £31
    Travel time is 2h 15m longer, but you will save £15

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 50m 18:05 Lyon Lyon Avenue Tony Garnier Coach Stop 08:55 Prague Na Knížecí Station  Economy £51
FlixBus 16h 30m 05:20 Lyon Lyon Avenue Tony Garnier Coach Stop 21:50 Prague ÚAN Florenc  Economy £51
FlixBus 15h 15m 18:05 Lyon Lyon Avenue Tony Garnier Coach Stop 09:20 Prague ÚAN Florenc  Economy £51
BlaBlaCar Bus 18h 50m 14:55 Lyon Perrache Train Station 09:45 Prague ÚAN Florenc  Economy £53

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 18h 10m 22:00 Lyon Lyon Avenue Tony Garnier Coach Stop 16:10 Prague Černý Most  Economy £48
FlixBus 17h 5m 21:30 Lyon Lyon Avenue Tony Garnier Coach Stop 14:35 Prague Wilsonova Coach Station  Economy £49
FlixBus 17h 15m 21:30 Lyon Lyon Avenue Tony Garnier Coach Stop 14:45 Prague ÚAN Florenc  Economy £52
FlixBus 16h 30m 05:20 Lyon Lyon Avenue Tony Garnier Coach Stop 21:50 Prague ÚAN Florenc  Economy £54
FlixBus 19h 30m 11:30 Lyon Lyon Avenue Tony Garnier Coach Stop 07:00 Prague Wilsonova Coach Station  Economy £55

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 55m 17:05 Lyon Lyon Avenue Tony Garnier Coach Stop 18:00 Prague Wilsonova Coach Station  Economy £50
FlixBus 22h 45m 12:45 Lyon Lyon Avenue Tony Garnier Coach Stop 11:30 Prague Zličín  Economy £50
FlixBus 21h 50m 12:45 Lyon Lyon Avenue Tony Garnier Coach Stop 10:35 Prague Wilsonova Coach Station  Economy £51
FlixBus 18h 10m 22:00 Lyon Lyon Avenue Tony Garnier Coach Stop 16:10 Prague Černý Most  Economy £51
FlixBus 22h 25m 02:20 Lyon Lyon Avenue Tony Garnier Coach Stop 00:45 Prague Wilsonova Coach Station  Economy £52

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 14h 50m 18:05 Lyon Lyon Avenue Tony Garnier Coach Stop 08:55 Prague Na Knížecí Station  Economy £44
FlixBus 18h 10m 22:00 Lyon Lyon Avenue Tony Garnier Coach Stop 16:10 Prague Černý Most  Economy £44
FlixBus 15h 15m 18:05 Lyon Lyon Avenue Tony Garnier Coach Stop 09:20 Prague ÚAN Florenc  Economy £47
FlixBus 21h 15m 01:40 Lyon Lyon Avenue Tony Garnier Coach Stop 22:55 Prague Na Knížecí Station  Economy £59
FlixBus 19h 10m 02:20 Lyon Lyon Avenue Tony Garnier Coach Stop 21:30 Prague ÚAN Florenc  Economy £61

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 16h 30m 05:20 Lyon Lyon Avenue Tony Garnier Coach Stop 21:50 Prague ÚAN Florenc  Economy £47
FlixBus 17h 15m 21:30 Lyon Lyon Avenue Tony Garnier Coach Stop 14:45 Prague ÚAN Florenc  Economy £47
FlixBus 17h 5m 21:30 Lyon Lyon Avenue Tony Garnier Coach Stop 14:35 Prague Wilsonova Coach Station  Economy £48
BlaBlaCar Bus 21h 45m 12:00 Lyon Perrache Train Station 09:45 Prague ÚAN Florenc  Economy £52

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 17h 5m 21:30 Lyon Lyon Avenue Tony Garnier Coach Stop 14:35 Prague Wilsonova Coach Station  Economy £48
FlixBus 17h 15m 21:30 Lyon Lyon Avenue Tony Garnier Coach Stop 14:45 Prague ÚAN Florenc  Economy £48
FlixBus 17h 25m 22:00 Lyon Lyon Avenue Tony Garnier Coach Stop 15:25 Prague ÚAN Florenc  Economy £48
RegioJet 15h 55m 14:35 Lyon Lyon Avenue Tony Garnier Coach Stop 06:30 Prague ÚAN Florenc  Economy £66

Best Price Offer: The price for the cheapest coach from Lyon to Prague is £41 on 10/11/2026. Flexible travellers save on ticket prices.


What is the best day and time to travel by bus between Lyon and Prague?

Here is the frequency of all coach connections from Lyon to Prague. See on which day of the week you have more travel options and what time you have more bus trips to choose from.
Monday is the busiest day, with more than 22 daily coaches from Lyon to Prague. Sunday has instead the fewest connections, with only 10 daily coaches between Lyon and Prague.
The busiest time of the day is the Evening, with 60 coaches from Lyon to Prague, while Morning sees the fewest connections between Lyon and Prague, with 8 offers.

All facts for Lyon to Prague bus at a glance

Compare all coach operators like FlixBus, BlaBlaCar Bus and RegioJet that travel daily 16 times by bus from Lyon to Prague in one click. Book your Lyon to Prague bus ticket starting from £41!

Cheapest Bus £41
Fastest Bus 14h 50m
Earliest Coach 12:05
Latest Coach 22:00
Daily Bus Connections 16 Ø
Distance 860.7 km
Coach Companies FlixBus, BlaBlaCar Bus and RegioJet

What are the cheapest coach tickets from Lyon to Prague?

Every day, 16 buses from 3 coach companies leave Lyon for Prague. Check the table below to find the cheapest prices for coach tickets for this route, starting from 01/11/2026 and for the following days. Make sure get the cheapest bus ticket!

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 26/10
Tuesday 27/10
Wednesday 28/10
Thursday 29/10
Friday 30/10
Saturday 31/10
Sunday 01/11
£64
Monday 02/11
£51
Tuesday 03/11
£52
Wednesday 04/11
£50
Thursday 05/11
£61
Friday 06/11
£48
Saturday 07/11
£48
Sunday 08/11
£54
Monday 09/11
£43
Tuesday 10/11
£41
Wednesday 11/11
£49
Thursday 12/11
£45
Friday 13/11
£49
Saturday 14/11
£51
Sunday 15/11
£46
Monday 16/11
£41
Tuesday 17/11
£44
Wednesday 18/11
£43
Thursday 19/11
£43
Friday 20/11
£43
Saturday 21/11
£43
Sunday 22/11

The cheapest time to travel from Lyon to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Lyon to Prague, for the next 30 days.
With a price starting from £37, Tuesday is the cheapest day for a coach from Lyon to Prague. Sunday instead is the most expensive day with prices starting from £46.
Night is the cheapest day time for bus tickets from Lyon to Prague, with £37. Morning is the most expensive time of the day with prices starting from £54.

How to save money travelling from Lyon to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Lyon to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Lyon to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Lyon to Prague are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

Latest reviews for coach companies on the route Lyon - Prague

FlixBus
Théo, 20/11/2025
On débute avec 2h50 de retard cumulé à mi-chemin pour le premier car FlixBus… Correspondance du second car bien évidemment manquée, toujours avec FlixBus… Dernier transport de la journée… dommage! O ... On débute avec 2h50 de retard cumulé à mi-chemin pour le premier car FlixBus… Correspondance du second car bien évidemment manquée, toujours avec FlixBus… Dernier transport de la journée… dommage! On repassera le matin suivant… S'il nous est pas encore passé l'envie d'arriver à destination… Toujours en suppléments à ses frais… s'il vous plaît bien sûr! Certains apprécieraient peut-être ce type d'aventure surprise… À se retrouver paumé au beau milieu de la nuit à 500km de chez soi… À moitié assommé d'une première étape de trajet complètement hasardeuse… Lâché dans une ville inconnue depuis un car douteux approchant les 3h du matin. Résultat miraculeux : Finalement arrivé à destination… à l'état de zombie certes… mais bien arrivé… Et sûrement pas grâce à cette enseigne… pour le fait de réagir face à la situation… Et débarquer 26h49 après l'horaire de départ contre les 9h44 initialement prévues… Le tout triplant les coûts non reconnus du voyage "low cost"… On dit merci qui ?
FlixBus
Pat, 21/08/2024

Najbardziej słabe jest robienie zdjęć pasażerom..Czy chcecie zeby ktos z pasażerow został zamordowany... Akurat to jest przestepstwo...

All bus stations and stops in Lyon and Prague

Here is a map with all coach stations in Lyon and Prague. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Lyon to Prague? Compare all modes of transports from Lyon to Prague.

All you need to know when you travel by bus from Lyon to Prague

Check all information on comfort and services on the coaches from Lyon to Prague. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Lyon to Prague bus

How much does a Lyon Prague coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Lyon Prague bus trip is available from £41 and takes 14h 50m. Compare offers and save money!

How much could I save by comparing buses from Lyon to Prague?

This connection is offered by 3 companies with ticket prices ranging from £41 to £101. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Prague.

How many connections are available for the Lyon Prague route on average every day?

Each day, the bus route from Lyon to Prague is offered by roughly 16 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Prague from Lyon take?

The quickest coach from Lyon to Prague is provided by FlixBus and takes 14h 50m. Coach tickets for this connection cost £69. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Lyon to Prague?

The earliest bus to Prague departs from Lyon at 12:05. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Lyon to Prague?

The latest bus to Prague departs from Lyon at 22:00. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Lyon Prague route?

Passengers looking to travel from Lyon to Prague can travel with FlixBus, BlaBlaCar Bus and RegioJet. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Lyon and Prague?

You can check all the direct connections between Lyon and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, BlaBlaCar Bus and RegioJet.

What can I take with me on the bus to Prague from Lyon?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Lyon Prague bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Lyon Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lyon to Prague on your planned travel date.

How does CheckMyBus find the best coach deals from Lyon to Prague?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 16 daily trips between Lyon and Prague. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Lyon to Prague?

Prices and availability for 16 trips between Lyon and Prague change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Lyon to Prague

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lyon and to Prague

Here’s an overview of the most popular bus routes to Lyon and to Prague. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
Coach Naples to Lyon Coach Naples to Lyon
Bus to Lyon from Brussels Bus to Lyon from Brussels
Buses Birmingham to Lyon Buses Birmingham to Lyon
Coach from Limoges to Lyon Coach from Limoges to Lyon
Bus Kolín to Prague Bus Kolín to Prague
Bus Memmingen to Prague Bus Memmingen to Prague
Bus Trencin to Prague Bus Trencin to Prague
Linz to Prague bus Linz to Prague bus
Popular Airport Transfers to Lyon and to Prague
CheckMyBus › Coaches in France › Coach to Lyon › Coach to Prague

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

deals,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

for

ads

personalisation.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.