Bus tickets Lyon to Prague from £45

Find a coach from Lyon to Prague: Compare 2 companies
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Which bus from Lyon to Prague is the best?

Check the bus schedule for Lyon to Prague. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or BlaBlaCar Bus. To see the full timetable for all coaches just use or search and compare.

today
from £52
tomorrow
from £50
Thursday
from £47
Friday
from £45
Saturday
from £45
Sunday
from £56
Monday
from £45

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    19h 45m
    0
    01:25
    Lyon
    Perrache Bus Stop
    21:10
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £52
  • FlixBus
    17h 35m
    0
    05:20
    Lyon
    Perrache Bus Stop
    22:55
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £52
  • FlixBus
    18h 45m
    0
    03:30
    Lyon
    Perrache Bus Stop
    22:15
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £52
  • FlixBus
    19h 5m
    0
    05:20
    Lyon
    Perrache Bus Stop
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £52
  • FlixBus
    20h 30m
    0
    09:30
    Lyon
    Perrache Bus Stop
    06:00
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £52

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    17h 35m
    0
    05:20
    Lyon
    Perrache Bus Stop
    22:55
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £50
  • FlixBus
    14h 40m
    0
    18:15
    Lyon
    Perrache Bus Stop
    08:55
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £50
  • FlixBus
    15h 5m
    0
    18:15
    Lyon
    Perrache Bus Stop
    09:20
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £50
  • FlixBus
    20h 30m
    0
    09:30
    Lyon
    Perrache Bus Stop
    06:00
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £54
  • FlixBus
    20h 45m
    0
    09:30
    Lyon
    Perrache Bus Stop
    06:15
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £54

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    17h 25m
    0
    22:00
    Lyon
    Perrache Bus Stop
    15:25
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £47
  • FlixBus
    18h 10m
    0
    22:00
    Lyon
    Perrache Bus Stop
    16:10
    Prague
    Černý Most
    0
    FlixBus
    Economy
    £47
  • FlixBus
    14h 40m
    0
    18:15
    Lyon
    Perrache Bus Stop
    08:55
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £50
  • FlixBus
    16h 30m
    0
    05:20
    Lyon
    Perrache Bus Stop
    21:50
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £50
  • FlixBus
    15h 5m
    0
    18:15
    Lyon
    Perrache Bus Stop
    09:20
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £50

Cheapest bus trips Friday

Prices are for one way and one person
  • BlaBlaCar Bus
    16h 25m
    0
    03:00
    Lyon
    Perrache Bus Stop
    19:25
    Prague
    ÚAN Florenc
    0
    BlaBlaCar Bus
    Economy
    £45
  • BlaBlaCar Bus
    16h 25m
    0
    03:00
    Lyon
    Perrache Train Station
    19:25
    Prague
    ÚAN Florenc
    0
    BlaBlaCar Bus
    Economy
    £45
  • FlixBus
    16h 55m
    0
    21:00
    Lyon
    Perrache Bus Stop
    13:55
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £49
  • FlixBus
    17h 5m
    0
    21:00
    Lyon
    Perrache Bus Stop
    14:05
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £49
  • FlixBus
    14h 40m
    0
    18:15
    Lyon
    Perrache Bus Stop
    08:55
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £56

Cheapest bus trips Saturday

Prices are for one way and one person
  • BlaBlaCar Bus
    16h 25m
    0
    03:00
    Lyon
    Perrache Train Station
    19:25
    Prague
    ÚAN Florenc
    0
    BlaBlaCar Bus
    Economy
    £45
  • BlaBlaCar Bus
    16h 25m
    0
    03:00
    Lyon
    Perrache Bus Stop
    19:25
    Prague
    ÚAN Florenc
    0
    BlaBlaCar Bus
    Economy
    £45
  • FlixBus
    19h 45m
    0
    01:25
    Lyon
    Perrache Bus Stop
    21:10
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £54
  • FlixBus
    17h 35m
    0
    05:20
    Lyon
    Perrache Bus Stop
    22:55
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £54
  • FlixBus
    18h 45m
    0
    03:30
    Lyon
    Perrache Bus Stop
    22:15
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £54

Cheapest bus trips Sunday

Prices are for one way and one person
  • FlixBus
    16h 55m
    0
    21:00
    Lyon
    Perrache Bus Stop
    13:55
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £56
  • FlixBus
    17h 5m
    0
    21:00
    Lyon
    Perrache Bus Stop
    14:05
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £56
  • FlixBus
    17h 25m
    0
    22:00
    Lyon
    Perrache Bus Stop
    15:25
    Prague
    ÚAN Florenc
    0
    FlixBus
    Economy
    £56
  • FlixBus
    18h 10m
    0
    22:00
    Lyon
    Perrache Bus Stop
    16:10
    Prague
    Černý Most
    0
    FlixBus
    Economy
    £56
  • FlixBus
    17h 45m
    0
    17:05
    Lyon
    Perrache Bus Stop
    10:50
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £65
  • Did you know that if you travel from Lyon to Prague via Zurich, you can save more than £17? You can find the corresponding connections below.
    • FlixBus
      22h 20m
      0
      08:05
      Lyon
      Perrache Bus Stop
      14:50
      Zurich
      Central Bus Station Sihlquai
      0
      FlixBus
      Economy
      £15
      • Waiting Time 6h 0m
    • RegioJet
      9h 35m
      0
      20:50
      Zurich
      Central Bus Station Sihlquai
      06:25
      Prague
      Train station Wilsonova
      0
      RegioJet
      Economy
      £24
    Travel time is 5h 25m longer, but you will save £17

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    17h 35m
    0
    05:20
    Lyon
    Perrache Bus Stop
    22:55
    Prague
    Na Knížecí Station
    0
    FlixBus
    Economy
    £45
  • FlixBus
    19h 0m
    0
    03:15
    Lyon
    Perrache Bus Stop
    22:15
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £45
  • FlixBus
    19h 5m
    0
    05:20
    Lyon
    Perrache Bus Stop
    00:25
    Prague
    Wilsonova Coach Station
    0
    FlixBus
    Economy
    £45
  • BlaBlaCar Bus
    16h 25m
    0
    03:00
    Lyon
    Perrache Train Station
    19:25
    Prague
    ÚAN Florenc
    0
    BlaBlaCar Bus
    Economy
    £45
  • BlaBlaCar Bus
    16h 25m
    0
    03:00
    Lyon
    Perrache Bus Stop
    19:25
    Prague
    ÚAN Florenc
    0
    BlaBlaCar Bus
    Economy
    £45
  • Did you know that if you travel from Lyon to Prague via Zurich, you can save more than £6? You can find the corresponding connections below.
    • FlixBus
      22h 20m
      0
      08:05
      Lyon
      Perrache Bus Stop
      14:50
      Zurich
      Central Bus Station Sihlquai
      0
      FlixBus
      Economy
      £15
      • Waiting Time 6h 0m
    • RegioJet
      9h 35m
      0
      20:50
      Zurich
      Central Bus Station Sihlquai
      06:25
      Prague
      Train station Wilsonova
      0
      RegioJet
      Economy
      £24
    Travel time is 5h 55m longer, but you will save £6

What is the best day and time to travel by bus between Lyon and Prague?

Here is the frequency of all coach connections from Lyon to Prague. See on which day of the week you have more travel options and what time you have more bus trips to choose from.
Monday is the busiest day, with more than 18 daily coaches from Lyon to Prague. Wednesday has instead the fewest connections, with only 12 daily coaches between Lyon and Prague.
The busiest time of the day is the Night, with 44 coaches from Lyon to Prague, while Afternoon sees the fewest connections between Lyon and Prague, with 7 offers.

All facts for Lyon to Prague bus at a glance

Compare all coach operators like FlixBus and BlaBlaCar Bus that travel daily 15 times by bus from Lyon to Prague in one click. Book your Lyon to Prague bus ticket starting from £45!

Cheapest Bus £45
Fastest Bus 14h 40m
Earliest Coach 01:25
Latest Coach 22:00
Daily Bus Connections 15 Ø
Distance 860.7 km
Coach Companies FlixBus and BlaBlaCar Bus

What are the cheapest coach tickets from Lyon to Prague?

Every day, 15 buses from 2 coach companies leave Lyon for Prague. Check the table below to find the cheapest prices for coach tickets for this route, starting from 17/06/2025 and for the following days. Make sure get the cheapest bus ticket!

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 16/06
Tuesday 17/06
£52
Wednesday 18/06
£50
Thursday 19/06
£47
Friday 20/06
£45
Saturday 21/06
£45
Sunday 22/06
£56
Monday 23/06
£45
Tuesday 24/06
£42
Wednesday 25/06
£43
Thursday 26/06
£42
Friday 27/06
£45
Saturday 28/06
£45
Sunday 29/06
£55
Monday 30/06
£48
Tuesday 01/07
£45
Wednesday 02/07
£50
Thursday 03/07
£55
Friday 04/07
£63
Saturday 05/07
£60
Sunday 06/07
£51
Monday 07/07
£51
Tuesday 08/07
£46
Wednesday 09/07
£49
Thursday 10/07
£50
Friday 11/07
£61
Saturday 12/07
£68
Sunday 13/07

The cheapest time to travel from Lyon to Prague

See here on which day and which time of the day you can find the cheapest bus ticket from Lyon to Prague, for the next 30 days.
With a price starting from £45, Monday is the cheapest day for a coach from Lyon to Prague. Sunday instead is the most expensive day with prices starting from £56.
Afternoon is the cheapest day time for bus tickets from Lyon to Prague, with £45. Evening is the most expensive time of the day with prices starting from £46.

How to save money travelling from Lyon to Prague

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Lyon to Prague in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Lyon to Prague, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Lyon to Prague are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

Latest reviews for coach companies on the route Lyon - Prague

FlixBus
Pat, 21/08/2024

Najbardziej słabe jest robienie zdjęć pasażerom..Czy chcecie zeby ktos z pasażerow został zamordowany... Akurat to jest przestepstwo...

All bus stations and stops in Lyon and Prague

Here is a map with all coach stations in Lyon and Prague. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Lyon to Prague? Compare all modes of transports from Lyon to Prague.

All you need to know when you travel by bus from Lyon to Prague

Check all information on comfort and services on the coaches from Lyon to Prague. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Lyon to Prague bus

How much does a Lyon Prague coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Lyon Prague bus trip is available from £45 and takes 17h 35m. Compare offers and save money!

How much could I save by comparing buses from Lyon to Prague?

This connection is offered by 2 companies with ticket prices ranging from £45 to £97. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to Prague.

How many connections are available for the Lyon Prague route on average every day?

Each day, the bus route from Lyon to Prague is offered by roughly 15 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to Prague from Lyon take?

The quickest coach from Lyon to Prague is provided by FlixBus and takes 14h 40m. Coach tickets for this connection cost £56. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Lyon to Prague?

The earliest bus to Prague departs from Lyon at 01:25. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Lyon to Prague?

The latest bus to Prague departs from Lyon at 22:00. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Lyon Prague route?

Passengers looking to travel from Lyon to Prague can travel with FlixBus and BlaBlaCar Bus. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Lyon and Prague?

You can check all the direct connections between Lyon and Prague by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and BlaBlaCar Bus.

What can I take with me on the bus to Prague from Lyon?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Lyon Prague bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Lyon Prague bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Lyon to Prague on your planned travel date.

Available seat classes which are offered on the bus route Lyon to Prague

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Lyon and to Prague

Here’s an overview of the most popular bus routes to Lyon and to Prague. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
Bus Aime-la-Plagne to Lyon Bus Aime-la-Plagne to Lyon
Coach from Moutiers to Lyon Coach from Moutiers to Lyon
Coach to Lyon from Bordeaux Coach to Lyon from Bordeaux
Coach to Lyon from Nantes Coach to Lyon from Nantes
Florence to Prague bus Florence to Prague bus
Gdańsk to Prague coach Gdańsk to Prague coach
Coaches Hamburg to Prague Coaches Hamburg to Prague
Linz to Prague bus Linz to Prague bus
Popular Airport Transfers to Lyon and to Prague
CheckMyBus › Coaches in France › Coach to Lyon › Coach to Prague

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To show you the best bus deals, we and our partners use technical, analytical, and marketing cookies for ads personalisation. We remember your anonymized details to provide a personalized experience.