What is the best way to travel from Lyon to Prague?
Looking for a trip? Check and compare all the available Flights and Buses to Prague from Lyon. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Lyon?
You can reach Prague with just £39 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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EasyJet Airline18h 55m021:30Lyons St. Exupery AirportLyons St. Exupery Airport16:25Prague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 06/02/2026 21:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 07/02/2026 16:25:00. 50 Economy ticket for £83 per person are available. Travel duration is 18h 55m
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Volotea1h 40m007:30Lyons St. Exupery AirportLyons St. Exupery Airport09:10Prague AirportPrague Airport0EconomyA Flight from Volotea goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 06/02/2026 07:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 06/02/2026 09:10:00. 50 Economy ticket for £111 per person are available. Travel duration is 1h 40m
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Austrian Airlines3h 10m012:50Lyons St. Exupery AirportLyons St. Exupery Airport16:00Prague AirportPrague Airport0EconomyA Flight from Austrian Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 06/02/2026 12:50:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 06/02/2026 16:00:00. 50 Economy ticket for £122 per person are available. Travel duration is 3h 10m
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Brussels Airlines6h 5m011:50Lyons St. Exupery AirportLyons St. Exupery Airport17:55Prague AirportPrague Airport0EconomyA Flight from Brussels Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 06/02/2026 11:50:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 06/02/2026 17:55:00. 50 Economy ticket for £134 per person are available. Travel duration is 6h 5m
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Lufthansa7h 20m015:05Lyons St. Exupery AirportLyons St. Exupery Airport22:25Prague AirportPrague Airport0EconomyA Flight from Lufthansa goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 06/02/2026 15:05:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 06/02/2026 22:25:00. 50 Economy ticket for £153 per person are available. Travel duration is 7h 20m
Cheapest Flights Friday
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RegioJet15h 50m014:35LyonPerrache Bus Stop06:25PragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Perrache Bus Stop, Lyon (France) at 07/02/2026 14:35:00 to Train station Wilsonova, Prague (Czech Republic) arriving at 08/02/2026 06:25:00. 50 Economy ticket for £43 per person are available. Travel duration is 15h 50m
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Wizz Air23h 40m014:20Lyons St. Exupery AirportLyons St. Exupery Airport14:00Prague AirportPrague Airport0EconomyA Flight from Wizz Air goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 07/02/2026 14:20:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 14:00:00. 50 Economy ticket for £103 per person are available. Travel duration is 23h 40m
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EasyJet Airline26h 40m016:25Lyons St. Exupery AirportLyons St. Exupery Airport19:05Prague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 07/02/2026 16:25:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 19:05:00. 50 Economy ticket for £109 per person are available. Travel duration is 26h 40m
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Vueling Airlines21h 45m019:40Lyons St. Exupery AirportLyons St. Exupery Airport17:25Prague AirportPrague Airport0EconomyA Flight from Vueling Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 07/02/2026 19:40:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 17:25:00. 50 Economy ticket for £129 per person are available. Travel duration is 21h 45m
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Iberia14h 30m019:40Lyons St. Exupery AirportLyons St. Exupery Airport10:10Prague AirportPrague Airport0EconomyA Flight from Iberia goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 07/02/2026 19:40:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 10:10:00. 50 Economy ticket for £204 per person are available. Travel duration is 14h 30m
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Austrian Airlines8h 10m014:30Lyons St. Exupery AirportLyons St. Exupery Airport22:40Prague AirportPrague Airport0EconomyA Flight from Austrian Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 07/02/2026 14:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 07/02/2026 22:40:00. 50 Economy ticket for £326 per person are available. Travel duration is 8h 10m
Cheapest Buses Saturday
Cheapest Flights Saturday
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FlixBus15h 50m017:05Lyons St. Exupery AirportLyons St. Exupery Airport08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 08/02/2026 17:05:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 09/02/2026 08:55:00. 50 Economy ticket for £55 per person are available. Travel duration is 15h 50m
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FlixBus16h 15m017:05Lyons St. Exupery AirportLyons St. Exupery Airport09:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 08/02/2026 17:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/02/2026 09:20:00. 50 Economy ticket for £55 per person are available. Travel duration is 16h 15m
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FlixBus22h 15m017:55Lyons St. Exupery AirportLyons St. Exupery Airport16:10PragueČerný Most0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 08/02/2026 17:55:00 to Černý Most, Prague (Czech Republic) arriving at 09/02/2026 16:10:00. 50 Economy ticket for £55 per person are available. Travel duration is 22h 15m
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STARSHIPPER SAS21h 55m016:40Lyons St. Exupery AirportLyons St. Exupery Airport14:35PragueWilsonova Coach Station0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 08/02/2026 16:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/02/2026 14:35:00. 50 Economy ticket for £68 per person are available. Travel duration is 21h 55m
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EasyJet Airline1h 40m017:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station19:25Prague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 08/02/2026 17:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/02/2026 19:25:00. 50 Economy ticket for £104 per person are available. Travel duration is 1h 40m
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Vueling Airlines9h 5m008:20Lyons St. Exupery AirportLyons St. Exupery Airport17:25Prague AirportPrague Airport0EconomyA Flight from Vueling Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 08/02/2026 08:20:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 17:25:00. 50 Economy ticket for £149 per person are available. Travel duration is 9h 5m
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LOT Polish Airlines / Polskie Linie Lotnicze13h 35m019:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:50Prague AirportPrague Airport - T1/20EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 08/02/2026 19:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/02/2026 08:50:00. 50 Economy ticket for £151 per person are available. Travel duration is 13h 35m
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Lufthansa3h 30m010:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station14:05Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 08/02/2026 10:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/02/2026 14:05:00. 50 Economy ticket for £190 per person are available. Travel duration is 3h 30m
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Austrian Airlines3h 10m012:50Lyons St. Exupery AirportLyons St. Exupery Airport16:00Prague AirportPrague Airport0EconomyA Flight from Austrian Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 08/02/2026 12:50:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 16:00:00. 50 Economy ticket for £190 per person are available. Travel duration is 3h 10m
Cheapest Buses Sunday
Cheapest Flights Sunday
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FlixBus20h 30m002:25LyonPerrache Bus Stop22:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 09/02/2026 02:25:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 09/02/2026 22:55:00. 50 Economy ticket for £39 per person are available. Travel duration is 20h 30m
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FlixBus19h 55m002:25LyonPerrache Bus Stop22:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 09/02/2026 02:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/02/2026 22:20:00. 50 Economy ticket for £39 per person are available. Travel duration is 19h 55m
Cheapest Buses Monday
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Wizz Air21h 40m018:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station16:35Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/02/2026 18:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 11/02/2026 16:35:00. 50 Economy ticket for £48 per person are available. Travel duration is 21h 40m
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Air Bagan5h 55m014:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:15Prague AirportPrague Airport - T1/20EconomyA Flight from Air Bagan goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/02/2026 14:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/02/2026 20:15:00. 50 Economy ticket for £81 per person are available. Travel duration is 5h 55m
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EasyJet Airline6h 10m014:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:15Prague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/02/2026 14:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/02/2026 20:15:00. 50 Economy ticket for £93 per person are available. Travel duration is 6h 10m
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Iberia6h 30m012:25Lyons St. Exupery AirportLyons St. Exupery Airport18:55Prague AirportPrague Airport0EconomyA Flight from Iberia goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 10/02/2026 12:25:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 10/02/2026 18:55:00. 50 Economy ticket for £144 per person are available. Travel duration is 6h 30m
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LOT Polish Airlines / Polskie Linie Lotnicze6h 5m011:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station17:15Prague AirportPrague Airport - T1/20EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/02/2026 11:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/02/2026 17:15:00. 50 Economy ticket for £151 per person are available. Travel duration is 6h 5m
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STARSHIPPER SAS22h 5m016:40Lyons St. Exupery AirportLyons St. Exupery Airport14:45PragueÚAN Florenc0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 10/02/2026 16:40:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 11/02/2026 14:45:00. 50 Economy ticket for £54 per person are available. Travel duration is 22h 5m
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STARSHIPPER SAS21h 55m016:40Lyons St. Exupery AirportLyons St. Exupery Airport14:35PragueWilsonova Coach Station0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 10/02/2026 16:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/02/2026 14:35:00. 50 Economy ticket for £54 per person are available. Travel duration is 21h 55m
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STARSHIPPER SAS19h 10m014:10Lyons St. Exupery AirportLyons St. Exupery Airport09:20PragueÚAN Florenc0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 10/02/2026 14:10:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 11/02/2026 09:20:00. 50 Economy ticket for £56 per person are available. Travel duration is 19h 10m
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FlixBus24h 10m007:30Lyons St. Exupery AirportLyons St. Exupery Airport07:40PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 10/02/2026 07:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 11/02/2026 07:40:00. 50 Economy ticket for £61 per person are available. Travel duration is 24h 10m
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FlixBus27h 25m019:30Lyons St. Exupery AirportLyons St. Exupery Airport22:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 10/02/2026 19:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 11/02/2026 22:55:00. 50 Economy ticket for £72 per person are available. Travel duration is 27h 25m
Cheapest Flights Tuesday
Cheapest Buses Tuesday
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EasyJet Airline7h 5m011:30Lyons St. Exupery AirportLyons St. Exupery Airport18:35Prague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 11/02/2026 11:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 11/02/2026 18:35:00. 50 Economy ticket for £121 per person are available. Travel duration is 7h 5m
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Lufthansa4h 10m008:55Lyons St. Exupery AirportLyons St. Exupery Airport13:05Prague AirportPrague Airport0EconomyA Flight from Lufthansa goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 11/02/2026 08:55:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 11/02/2026 13:05:00. 50 Economy ticket for £155 per person are available. Travel duration is 4h 10m
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Brussels Airlines6h 5m011:50Lyons St. Exupery AirportLyons St. Exupery Airport17:55Prague AirportPrague Airport0EconomyA Flight from Brussels Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 11/02/2026 11:50:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 11/02/2026 17:55:00. 50 Economy ticket for £160 per person are available. Travel duration is 6h 5m
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Austrian Airlines3h 10m012:50Lyons St. Exupery AirportLyons St. Exupery Airport16:00Prague AirportPrague Airport0EconomyA Flight from Austrian Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 11/02/2026 12:50:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 11/02/2026 16:00:00. 50 Economy ticket for £160 per person are available. Travel duration is 3h 10m
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Vueling Airlines25h 55m008:15Lyons St. Exupery AirportLyons St. Exupery Airport10:10Prague AirportPrague Airport0EconomyA Flight from Vueling Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 11/02/2026 08:15:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 12/02/2026 10:10:00. 50 Economy ticket for £164 per person are available. Travel duration is 25h 55m
Cheapest Flights Wednesday
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EasyJet Airline1h 40m013:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station15:25Prague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/02/2026 13:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/02/2026 15:25:00. 50 Economy ticket for £74 per person are available. Travel duration is 1h 40m
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Vueling Airlines12h 10m008:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:30Prague AirportPrague Airport - T1/20EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/02/2026 08:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/02/2026 20:30:00. 50 Economy ticket for £150 per person are available. Travel duration is 12h 10m
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Lufthansa CityLine4h 10m008:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station13:05Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa CityLine goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/02/2026 08:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/02/2026 13:05:00. 50 Economy ticket for £153 per person are available. Travel duration is 4h 10m
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Brussels Airlines6h 5m011:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station17:55Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/02/2026 11:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/02/2026 17:55:00. 50 Economy ticket for £158 per person are available. Travel duration is 6h 5m
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KLM - Royal Dutch Airlines18h 15m014:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:25Prague AirportPrague Airport - T1/20EconomyA Flight from KLM - Royal Dutch Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/02/2026 14:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 13/02/2026 08:25:00. 50 Economy ticket for £164 per person are available. Travel duration is 18h 15m
Cheapest Flights Thursday
What are the fastest trips from Lyon to Prague?
You can get to Prague from Lyon in just 1h 40m with a Flight from Volotea. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Volotea1h 40m007:30Lyons St. Exupery AirportLyons St. Exupery Airport09:10Prague AirportPrague Airport0EconomyA Flight from Volotea goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 06/02/2026 07:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 06/02/2026 09:10:00. 50 Economy ticket for £111 per person are available. Travel duration is 1h 40m
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Austrian Airlines3h 10m012:50Lyons St. Exupery AirportLyons St. Exupery Airport16:00Prague AirportPrague Airport0EconomyA Flight from Austrian Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 06/02/2026 12:50:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 06/02/2026 16:00:00. 50 Economy ticket for £122 per person are available. Travel duration is 3h 10m
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Brussels Airlines6h 5m011:50Lyons St. Exupery AirportLyons St. Exupery Airport17:55Prague AirportPrague Airport0EconomyA Flight from Brussels Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 06/02/2026 11:50:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 06/02/2026 17:55:00. 50 Economy ticket for £134 per person are available. Travel duration is 6h 5m
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Lufthansa7h 20m015:05Lyons St. Exupery AirportLyons St. Exupery Airport22:25Prague AirportPrague Airport0EconomyA Flight from Lufthansa goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 06/02/2026 15:05:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 06/02/2026 22:25:00. 50 Economy ticket for £153 per person are available. Travel duration is 7h 20m
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EasyJet Airline18h 55m021:30Lyons St. Exupery AirportLyons St. Exupery Airport16:25Prague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 06/02/2026 21:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 07/02/2026 16:25:00. 50 Economy ticket for £83 per person are available. Travel duration is 18h 55m
Fastest Flights Friday
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Austrian Airlines8h 10m014:30Lyons St. Exupery AirportLyons St. Exupery Airport22:40Prague AirportPrague Airport0EconomyA Flight from Austrian Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 07/02/2026 14:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 07/02/2026 22:40:00. 50 Economy ticket for £326 per person are available. Travel duration is 8h 10m
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Iberia14h 30m019:40Lyons St. Exupery AirportLyons St. Exupery Airport10:10Prague AirportPrague Airport0EconomyA Flight from Iberia goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 07/02/2026 19:40:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 10:10:00. 50 Economy ticket for £204 per person are available. Travel duration is 14h 30m
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Vueling Airlines21h 45m019:40Lyons St. Exupery AirportLyons St. Exupery Airport17:25Prague AirportPrague Airport0EconomyA Flight from Vueling Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 07/02/2026 19:40:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 17:25:00. 50 Economy ticket for £129 per person are available. Travel duration is 21h 45m
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Wizz Air23h 40m014:20Lyons St. Exupery AirportLyons St. Exupery Airport14:00Prague AirportPrague Airport0EconomyA Flight from Wizz Air goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 07/02/2026 14:20:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 14:00:00. 50 Economy ticket for £103 per person are available. Travel duration is 23h 40m
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EasyJet Airline26h 40m016:25Lyons St. Exupery AirportLyons St. Exupery Airport19:05Prague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 07/02/2026 16:25:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 19:05:00. 50 Economy ticket for £109 per person are available. Travel duration is 26h 40m
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RegioJet15h 50m014:35LyonPerrache Bus Stop06:25PragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Perrache Bus Stop, Lyon (France) at 07/02/2026 14:35:00 to Train station Wilsonova, Prague (Czech Republic) arriving at 08/02/2026 06:25:00. 50 Economy ticket for £43 per person are available. Travel duration is 15h 50m
Fastest Flights Saturday
Fastest Buses Saturday
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EasyJet Airline1h 40m017:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station19:25Prague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 08/02/2026 17:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/02/2026 19:25:00. 50 Economy ticket for £104 per person are available. Travel duration is 1h 40m
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Austrian Airlines3h 10m012:50Lyons St. Exupery AirportLyons St. Exupery Airport16:00Prague AirportPrague Airport0EconomyA Flight from Austrian Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 08/02/2026 12:50:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 16:00:00. 50 Economy ticket for £190 per person are available. Travel duration is 3h 10m
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Lufthansa3h 30m010:35Lyons St. Exupery AirportAéroport St Exupéry Coach Station14:05Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 08/02/2026 10:35:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 08/02/2026 14:05:00. 50 Economy ticket for £190 per person are available. Travel duration is 3h 30m
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Vueling Airlines9h 5m008:20Lyons St. Exupery AirportLyons St. Exupery Airport17:25Prague AirportPrague Airport0EconomyA Flight from Vueling Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 08/02/2026 08:20:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 08/02/2026 17:25:00. 50 Economy ticket for £149 per person are available. Travel duration is 9h 5m
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LOT Polish Airlines / Polskie Linie Lotnicze13h 35m019:15Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:50Prague AirportPrague Airport - T1/20EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 08/02/2026 19:15:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 09/02/2026 08:50:00. 50 Economy ticket for £151 per person are available. Travel duration is 13h 35m
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FlixBus15h 50m017:05Lyons St. Exupery AirportLyons St. Exupery Airport08:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 08/02/2026 17:05:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 09/02/2026 08:55:00. 50 Economy ticket for £55 per person are available. Travel duration is 15h 50m
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FlixBus16h 15m017:05Lyons St. Exupery AirportLyons St. Exupery Airport09:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 08/02/2026 17:05:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/02/2026 09:20:00. 50 Economy ticket for £55 per person are available. Travel duration is 16h 15m
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STARSHIPPER SAS21h 55m016:40Lyons St. Exupery AirportLyons St. Exupery Airport14:35PragueWilsonova Coach Station0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 08/02/2026 16:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 09/02/2026 14:35:00. 50 Economy ticket for £68 per person are available. Travel duration is 21h 55m
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FlixBus22h 15m017:55Lyons St. Exupery AirportLyons St. Exupery Airport16:10PragueČerný Most0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 08/02/2026 17:55:00 to Černý Most, Prague (Czech Republic) arriving at 09/02/2026 16:10:00. 50 Economy ticket for £55 per person are available. Travel duration is 22h 15m
Fastest Flights Sunday
Fastest Buses Sunday
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FlixBus19h 55m002:25LyonPerrache Bus Stop22:20PragueÚAN Florenc0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 09/02/2026 02:25:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 09/02/2026 22:20:00. 50 Economy ticket for £39 per person are available. Travel duration is 19h 55m
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FlixBus20h 30m002:25LyonPerrache Bus Stop22:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Perrache Bus Stop, Lyon (France) at 09/02/2026 02:25:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 09/02/2026 22:55:00. 50 Economy ticket for £39 per person are available. Travel duration is 20h 30m
Fastest Buses Monday
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Air Bagan5h 55m014:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:15Prague AirportPrague Airport - T1/20EconomyA Flight from Air Bagan goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/02/2026 14:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/02/2026 20:15:00. 50 Economy ticket for £81 per person are available. Travel duration is 5h 55m
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LOT Polish Airlines / Polskie Linie Lotnicze6h 5m011:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station17:15Prague AirportPrague Airport - T1/20EconomyA Flight from LOT Polish Airlines / Polskie Linie Lotnicze goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/02/2026 11:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/02/2026 17:15:00. 50 Economy ticket for £151 per person are available. Travel duration is 6h 5m
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EasyJet Airline6h 10m014:05Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:15Prague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/02/2026 14:05:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 10/02/2026 20:15:00. 50 Economy ticket for £93 per person are available. Travel duration is 6h 10m
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Iberia6h 30m012:25Lyons St. Exupery AirportLyons St. Exupery Airport18:55Prague AirportPrague Airport0EconomyA Flight from Iberia goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 10/02/2026 12:25:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 10/02/2026 18:55:00. 50 Economy ticket for £144 per person are available. Travel duration is 6h 30m
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Wizz Air21h 40m018:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station16:35Prague AirportPrague Airport - T1/20EconomyA Flight from Wizz Air goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 10/02/2026 18:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 11/02/2026 16:35:00. 50 Economy ticket for £48 per person are available. Travel duration is 21h 40m
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STARSHIPPER SAS19h 10m014:10Lyons St. Exupery AirportLyons St. Exupery Airport09:20PragueÚAN Florenc0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 10/02/2026 14:10:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 11/02/2026 09:20:00. 50 Economy ticket for £56 per person are available. Travel duration is 19h 10m
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STARSHIPPER SAS21h 55m016:40Lyons St. Exupery AirportLyons St. Exupery Airport14:35PragueWilsonova Coach Station0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 10/02/2026 16:40:00 to Wilsonova Coach Station, Prague (Czech Republic) arriving at 11/02/2026 14:35:00. 50 Economy ticket for £54 per person are available. Travel duration is 21h 55m
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STARSHIPPER SAS22h 5m016:40Lyons St. Exupery AirportLyons St. Exupery Airport14:45PragueÚAN Florenc0EconomyA Bus from STARSHIPPER SAS goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 10/02/2026 16:40:00 to ÚAN Florenc, Prague (Czech Republic) arriving at 11/02/2026 14:45:00. 50 Economy ticket for £54 per person are available. Travel duration is 22h 5m
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FlixBus24h 10m007:30Lyons St. Exupery AirportLyons St. Exupery Airport07:40PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 10/02/2026 07:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 11/02/2026 07:40:00. 50 Economy ticket for £61 per person are available. Travel duration is 24h 10m
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FlixBus27h 25m019:30Lyons St. Exupery AirportLyons St. Exupery Airport22:55PragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 10/02/2026 19:30:00 to Na Knížecí Station, Prague (Czech Republic) arriving at 11/02/2026 22:55:00. 50 Economy ticket for £72 per person are available. Travel duration is 27h 25m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Austrian Airlines3h 10m012:50Lyons St. Exupery AirportLyons St. Exupery Airport16:00Prague AirportPrague Airport0EconomyA Flight from Austrian Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 11/02/2026 12:50:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 11/02/2026 16:00:00. 50 Economy ticket for £160 per person are available. Travel duration is 3h 10m
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Lufthansa4h 10m008:55Lyons St. Exupery AirportLyons St. Exupery Airport13:05Prague AirportPrague Airport0EconomyA Flight from Lufthansa goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 11/02/2026 08:55:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 11/02/2026 13:05:00. 50 Economy ticket for £155 per person are available. Travel duration is 4h 10m
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Brussels Airlines6h 5m011:50Lyons St. Exupery AirportLyons St. Exupery Airport17:55Prague AirportPrague Airport0EconomyA Flight from Brussels Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 11/02/2026 11:50:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 11/02/2026 17:55:00. 50 Economy ticket for £160 per person are available. Travel duration is 6h 5m
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EasyJet Airline7h 5m011:30Lyons St. Exupery AirportLyons St. Exupery Airport18:35Prague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 11/02/2026 11:30:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 11/02/2026 18:35:00. 50 Economy ticket for £121 per person are available. Travel duration is 7h 5m
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Vueling Airlines25h 55m008:15Lyons St. Exupery AirportLyons St. Exupery Airport10:10Prague AirportPrague Airport0EconomyA Flight from Vueling Airlines goes from Lyons St. Exupery Airport, Lyons St. Exupery Airport (France) at 11/02/2026 08:15:00 to Prague Airport, Prague Airport (Czech Republic) arriving at 12/02/2026 10:10:00. 50 Economy ticket for £164 per person are available. Travel duration is 25h 55m
Fastest Flights Wednesday
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EasyJet Airline1h 40m013:45Lyons St. Exupery AirportAéroport St Exupéry Coach Station15:25Prague AirportPrague Airport - T1/20EconomyA Flight from EasyJet Airline goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/02/2026 13:45:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/02/2026 15:25:00. 50 Economy ticket for £74 per person are available. Travel duration is 1h 40m
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Lufthansa CityLine4h 10m008:55Lyons St. Exupery AirportAéroport St Exupéry Coach Station13:05Prague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa CityLine goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/02/2026 08:55:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/02/2026 13:05:00. 50 Economy ticket for £153 per person are available. Travel duration is 4h 10m
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Brussels Airlines6h 5m011:50Lyons St. Exupery AirportAéroport St Exupéry Coach Station17:55Prague AirportPrague Airport - T1/20EconomyA Flight from Brussels Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/02/2026 11:50:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/02/2026 17:55:00. 50 Economy ticket for £158 per person are available. Travel duration is 6h 5m
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Vueling Airlines12h 10m008:20Lyons St. Exupery AirportAéroport St Exupéry Coach Station20:30Prague AirportPrague Airport - T1/20EconomyA Flight from Vueling Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/02/2026 08:20:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/02/2026 20:30:00. 50 Economy ticket for £150 per person are available. Travel duration is 12h 10m
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KLM - Royal Dutch Airlines18h 15m014:10Lyons St. Exupery AirportAéroport St Exupéry Coach Station08:25Prague AirportPrague Airport - T1/20EconomyA Flight from KLM - Royal Dutch Airlines goes from Aéroport St Exupéry Coach Station, Lyons St. Exupery Airport (France) at 12/02/2026 14:10:00 to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 13/02/2026 08:25:00. 50 Economy ticket for £164 per person are available. Travel duration is 18h 15m
Fastest Flights Thursday
Here you will find all operators and timetables for a
Bus from Lyon to Prague
What are the most popular stations in Lyon and Prague?
In Lyon, you will usually depart from Perrache Bus Stop, Part-Dieu Train Station or Perrache Train Station, while in Prague you will be arriving at Wilsonova Coach Station, ÚAN Florenc or Černý Most, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Lyon? With 6 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Lyon and Prague, you can pay as low as £39 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Volotea: you will get to Prague in just 1h 40m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Lyon and Prague are FlixBus, EasyJet Airline and STARSHIPPER SAS, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Lyon and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Caluire-et-Cuire or to Horoměřice, and look at flights from Lyons St. Exupery Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Lyon to Prague?
The most popular companies between Lyon and Prague, are FlixBus, EasyJet Airline and STARSHIPPER SAS. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus, STARSHIPPER SAS and RegioJet
Airlines: EasyJet Airline, Austrian Airlines, Vueling Airlines and 9 more.
All you need to know when you travel from Lyon to Prague
Check all information on comfort and services on all modes of transports from Lyon to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Lyon to Prague
How can I reach Prague from Lyon?
Every day, there are on average 6 connections between Flight and Bus, with which you can get to Prague from Lyon.
How far is Prague from Lyon?
The distance between Lyon and Prague is 860.7 km.
What is the most ecofriendly mode of transport between Lyon and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 23 kgs of CO2, a train 30 kgs, a car 146 kgs, and a flight 212 kgs.
What is the cheapest mode of transport from Lyon to Prague?
You can get to Prague with just £39 by taking a Bus from FlixBus.
What is the fastest way to get from Lyon to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 40m with a Flight from Volotea.
More routes to Lyon and to Prague
Looking for more options? Here you can see the most popular routes to Lyon and to Prague. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Lyon
- Annecy to Lyon
- Barcelona to Lyon
- Basel to Lyon
- Bologna to Lyon
- Bordeaux to Lyon
- Chambery to Lyon
- Dijon to Lyon
- Dusseldorf to Lyon
- Geneva to Lyon
- Grenoble to Lyon
- Lisbon to Lyon
- London to Lyon
- Madrid to Lyon
- Marseille to Lyon
- Milan to Lyon
- Murcia to Lyon
- Nantes to Lyon
- Nice to Lyon
- Orleans to Lyon
- Paris to Lyon
- Rome to Lyon
- Toulouse to Lyon
- Turin to Lyon
- Valencia to Lyon
- Trips to Prague
- Banska Bystrica to Prague
- Berlin to Prague
- Bern to Prague
- Bologna to Prague
- Břeclav to Prague
- Český Krumlov to Prague
- Hamburg to Prague
- Hradec Kralove to Prague
- Humpolec to Prague
- Jihlava to Prague
- Kosice to Prague
- Munich to Prague
- Ostrava to Prague
- Paris to Prague
- Pilsen to Prague
- Presov to Prague
- Riga to Prague
- Rimavska Sobota to Prague
- Spisska Nova Ves to Prague
- St. Gallen to Prague
- Teplice to Prague
- Vienna to Prague
- Warsaw to Prague
- Wroclaw to Prague
