What is the best way to travel from La Serena to Santiago, RM?
Looking for a trip? Check and compare all the available Buses and Flights to Santiago, RM from La Serena. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 13 available companies to find your perfect trip!
What is the cheapest way to reach Santiago, RM from La Serena?
You can reach Santiago, RM with just £7 by taking a Bus from Buses Romani, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Buses Romani6h 15m000:45La SerenaCentral Coach Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Central Coach Station, La Serena (Chile) at 04/12/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 04/12/2025 07:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 15m
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Cikbus Elité7h 0m009:30La SerenaCentral Coach Station16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 04/12/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/12/2025 16:30:00. 50 Business ticket for £7 per person are available. Travel duration is 7h 0m
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FlixBus6h 5m006:00La SerenaCentral Coach Station12:05Santiago, RMTerminal San Borja0Premium EconomyA Bus from FlixBus goes from Central Coach Station, La Serena (Chile) at 04/12/2025 06:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/12/2025 12:05:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 5m
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Pullman Bus6h 0m004:30La SerenaCentral Coach Station10:30Santiago, RMTerminal San Borja0BusinessA Bus from Pullman Bus goes from Central Coach Station, La Serena (Chile) at 04/12/2025 04:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/12/2025 10:30:00. 50 Business ticket for £10 per person are available. Travel duration is 6h 0m
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Pullman San Andres6h 10m007:50La SerenaCentral Coach Station14:00Santiago, RMTerminal San Borja0First ClassA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 04/12/2025 07:50:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/12/2025 14:00:00. 50 First Class ticket for £10 per person are available. Travel duration is 6h 10m
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LAN Perú0h 58m011:50La Florida, La Serena AirportLa Florida, La Serena Airport12:48Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/12/2025 11:50:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/12/2025 12:48:00. 50 Economy ticket for £83 per person are available. Travel duration is 0h 58m
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JetSmart0h 59m012:59La Florida, La Serena AirportLa Florida, La Serena Airport13:58Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/12/2025 12:59:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/12/2025 13:58:00. 50 Economy ticket for £89 per person are available. Travel duration is 0h 59m
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Sky Airline1h 4m011:11La Florida, La Serena AirportLa Florida, La Serena Airport12:15Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/12/2025 11:11:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/12/2025 12:15:00. 50 Economy ticket for £103 per person are available. Travel duration is 1h 4m
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Sky Airline1h 4m019:53La Florida, La Serena AirportLa Florida, La Serena Airport20:57Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/12/2025 19:53:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/12/2025 20:57:00. 50 Economy ticket for £123 per person are available. Travel duration is 1h 4m
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LAN Perú0h 58m009:40La Florida, La Serena AirportLa Florida, La Serena Airport10:38Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/12/2025 09:40:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/12/2025 10:38:00. 50 Economy ticket for £133 per person are available. Travel duration is 0h 58m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Cikbus Elité7h 0m009:30La SerenaCentral Coach Station16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 05/12/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/12/2025 16:30:00. 50 Business ticket for £10 per person are available. Travel duration is 7h 0m
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Serena Mar6h 0m010:00La SerenaCentral Coach Station16:00Santiago, RMTerminal San Borja0First ClassA Bus from Serena Mar goes from Central Coach Station, La Serena (Chile) at 05/12/2025 10:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/12/2025 16:00:00. 50 First Class ticket for £10 per person are available. Travel duration is 6h 0m
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FlixBus6h 5m006:00La SerenaCentral Coach Station12:05Santiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Central Coach Station, La Serena (Chile) at 05/12/2025 06:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/12/2025 12:05:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 5m
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Condor Bus6h 50m003:15La SerenaCentral Coach Station10:05Santiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Central Coach Station, La Serena (Chile) at 05/12/2025 03:15:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/12/2025 10:05:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 50m
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Cormar Bus6h 40m000:15La SerenaCentral Coach Station06:55Santiago, RMTerminal San Borja0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 05/12/2025 00:15:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/12/2025 06:55:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 40m
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LAN Perú0h 58m012:34La Florida, La Serena AirportLa Florida, La Serena Airport13:32Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/12/2025 12:34:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/12/2025 13:32:00. 50 Economy ticket for £48 per person are available. Travel duration is 0h 58m
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JetSmart0h 59m013:08La Florida, La Serena AirportLa Florida, La Serena Airport14:07Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/12/2025 13:08:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/12/2025 14:07:00. 50 Economy ticket for £59 per person are available. Travel duration is 0h 59m
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LAN Airlines0h 57m022:25La Florida, La Serena AirportLa Florida, La Serena Airport23:22Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/12/2025 22:25:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/12/2025 23:22:00. 50 Economy ticket for £60 per person are available. Travel duration is 0h 57m
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Sky Airline1h 4m018:16La Florida, La Serena AirportLa Florida, La Serena Airport19:20Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/12/2025 18:16:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/12/2025 19:20:00. 50 Economy ticket for £68 per person are available. Travel duration is 1h 4m
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Sky Airline1h 4m020:04La Florida, La Serena AirportLa Florida, La Serena Airport21:08Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/12/2025 20:04:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/12/2025 21:08:00. 50 Economy ticket for £68 per person are available. Travel duration is 1h 4m
Cheapest Buses Friday
Cheapest Flights Friday
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Buses Romani6h 15m000:45La SerenaCentral Coach Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Central Coach Station, La Serena (Chile) at 06/12/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 06/12/2025 07:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 15m
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FlixBus6h 5m014:15La SerenaCentral Coach Station20:20Santiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Central Coach Station, La Serena (Chile) at 06/12/2025 14:15:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 06/12/2025 20:20:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 5m
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Condor Bus6h 15m016:50La SerenaCentral Coach Station23:05Santiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Central Coach Station, La Serena (Chile) at 06/12/2025 16:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 06/12/2025 23:05:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 6h 15m
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Cormar Bus6h 10m013:20La SerenaCentral Coach Station19:30Santiago, RMTerminal San Borja0First ClassA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 06/12/2025 13:20:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 06/12/2025 19:30:00. 50 First Class ticket for £11 per person are available. Travel duration is 6h 10m
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Turbus6h 25m012:00La SerenaAvda. Fco de Aguirre Station18:25Santiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 06/12/2025 12:00:00 to Terminal Alameda, Santiago, RM (Chile) arriving at 06/12/2025 18:25:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 25m
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JetSmart0h 59m010:27La Florida, La Serena AirportLa Florida, La Serena Airport11:26Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 06/12/2025 10:27:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 06/12/2025 11:26:00. 50 Economy ticket for £75 per person are available. Travel duration is 0h 59m
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Sky Airline1h 4m011:11La Florida, La Serena AirportLa Florida, La Serena Airport12:15Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 06/12/2025 11:11:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 06/12/2025 12:15:00. 50 Economy ticket for £77 per person are available. Travel duration is 1h 4m
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LAN Perú0h 57m019:45La Florida, La Serena AirportLa Florida, La Serena Airport20:42Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 06/12/2025 19:45:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 06/12/2025 20:42:00. 50 Economy ticket for £82 per person are available. Travel duration is 0h 57m
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LAN Perú0h 58m009:46La Florida, La Serena AirportLa Florida, La Serena Airport10:44Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 06/12/2025 09:46:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 06/12/2025 10:44:00. 50 Economy ticket for £83 per person are available. Travel duration is 0h 58m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Buses Romani6h 0m009:00La SerenaCentral Coach Station15:00Santiago, RMTerminal San Borja0BusinessA Bus from Buses Romani goes from Central Coach Station, La Serena (Chile) at 07/12/2025 09:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 07/12/2025 15:00:00. 50 Business ticket for £8 per person are available. Travel duration is 6h 0m
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FlixBus6h 5m015:30La SerenaCentral Coach Station21:35Santiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Central Coach Station, La Serena (Chile) at 07/12/2025 15:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 07/12/2025 21:35:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 5m
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Cikbus Elité7h 0m009:30La SerenaCentral Coach Station16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 07/12/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 07/12/2025 16:30:00. 50 Business ticket for £10 per person are available. Travel duration is 7h 0m
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Serena Mar6h 0m010:00La SerenaCentral Coach Station16:00Santiago, RMTerminal San Borja0First ClassA Bus from Serena Mar goes from Central Coach Station, La Serena (Chile) at 07/12/2025 10:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 07/12/2025 16:00:00. 50 First Class ticket for £10 per person are available. Travel duration is 6h 0m
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Condor Bus6h 35m001:45La SerenaCentral Coach Station08:20Santiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Central Coach Station, La Serena (Chile) at 07/12/2025 01:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 07/12/2025 08:20:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 6h 35m
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Sky Airline1h 4m011:01La Florida, La Serena AirportLa Florida, La Serena Airport12:05Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 07/12/2025 11:01:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 07/12/2025 12:05:00. 50 Economy ticket for £46 per person are available. Travel duration is 1h 4m
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JetSmart0h 59m010:44La Florida, La Serena AirportLa Florida, La Serena Airport11:43Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 07/12/2025 10:44:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 07/12/2025 11:43:00. 50 Economy ticket for £47 per person are available. Travel duration is 0h 59m
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LAN Perú0h 58m009:40La Florida, La Serena AirportLa Florida, La Serena Airport10:38Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 07/12/2025 09:40:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 07/12/2025 10:38:00. 50 Economy ticket for £48 per person are available. Travel duration is 0h 58m
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LAN Airlines0h 57m014:00La Florida, La Serena AirportLa Florida, La Serena Airport14:57Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 07/12/2025 14:00:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 07/12/2025 14:57:00. 50 Economy ticket for £53 per person are available. Travel duration is 0h 57m
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LAN Airlines0h 57m015:40La Florida, La Serena AirportLa Florida, La Serena Airport16:37Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 07/12/2025 15:40:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 07/12/2025 16:37:00. 50 Economy ticket for £58 per person are available. Travel duration is 0h 57m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Buses Romani6h 15m000:45La SerenaCentral Coach Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Central Coach Station, La Serena (Chile) at 08/12/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 08/12/2025 07:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 15m
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Turbus6h 15m002:30La SerenaAvda. Fco de Aguirre Station08:45Santiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 08/12/2025 02:30:00 to Terminal Alameda, Santiago, RM (Chile) arriving at 08/12/2025 08:45:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 15m
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Cikbus Elité7h 0m009:30La SerenaCentral Coach Station16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 08/12/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 08/12/2025 16:30:00. 50 Business ticket for £10 per person are available. Travel duration is 7h 0m
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Serena Mar6h 0m010:00La SerenaCentral Coach Station16:00Santiago, RMTerminal San Borja0First ClassA Bus from Serena Mar goes from Central Coach Station, La Serena (Chile) at 08/12/2025 10:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 08/12/2025 16:00:00. 50 First Class ticket for £10 per person are available. Travel duration is 6h 0m
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Cormar Bus6h 10m013:20La SerenaCentral Coach Station19:30Santiago, RMTerminal San Borja0First ClassA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 08/12/2025 13:20:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 08/12/2025 19:30:00. 50 First Class ticket for £12 per person are available. Travel duration is 6h 10m
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JetSmart0h 59m012:35La Florida, La Serena AirportLa Florida, La Serena Airport13:34Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 08/12/2025 12:35:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 08/12/2025 13:34:00. 50 Economy ticket for £76 per person are available. Travel duration is 0h 59m
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Sky Airline1h 4m012:19La Florida, La Serena AirportLa Florida, La Serena Airport13:23Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 08/12/2025 12:19:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 08/12/2025 13:23:00. 50 Economy ticket for £112 per person are available. Travel duration is 1h 4m
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LAN Airlines0h 58m013:32La Florida, La Serena AirportLa Florida, La Serena Airport14:30Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 08/12/2025 13:32:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 08/12/2025 14:30:00. 50 Economy ticket for £115 per person are available. Travel duration is 0h 58m
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LAN Perú0h 57m020:35La Florida, La Serena AirportLa Florida, La Serena Airport21:32Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 08/12/2025 20:35:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 08/12/2025 21:32:00. 50 Economy ticket for £118 per person are available. Travel duration is 0h 57m
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LAN Airlines0h 57m016:58La Florida, La Serena AirportLa Florida, La Serena Airport17:55Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 08/12/2025 16:58:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 08/12/2025 17:55:00. 50 Economy ticket for £121 per person are available. Travel duration is 0h 57m
Cheapest Buses Monday
Cheapest Flights Monday
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Buses Romani6h 0m009:00La SerenaCentral Coach Station15:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Central Coach Station, La Serena (Chile) at 09/12/2025 09:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 09/12/2025 15:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 0m
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Turbus6h 5m006:55La SerenaAvda. Fco de Aguirre Station13:00Santiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 09/12/2025 06:55:00 to Terminal Alameda, Santiago, RM (Chile) arriving at 09/12/2025 13:00:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 5m
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Cormar Bus6h 10m023:50La SerenaCentral Coach Station06:00Santiago, RMTerminal San Borja0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 09/12/2025 23:50:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 10/12/2025 06:00:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 10m
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Cikbus Elité7h 0m009:30La SerenaCentral Coach Station16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 09/12/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 09/12/2025 16:30:00. 50 Business ticket for £10 per person are available. Travel duration is 7h 0m
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Condor Bus6h 15m016:50La SerenaCentral Coach Station23:05Santiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Central Coach Station, La Serena (Chile) at 09/12/2025 16:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 09/12/2025 23:05:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 6h 15m
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JetSmart0h 59m010:30La Florida, La Serena AirportLa Florida, La Serena Airport11:29Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 09/12/2025 10:30:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 09/12/2025 11:29:00. 50 Economy ticket for £67 per person are available. Travel duration is 0h 59m
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LAN Perú0h 58m009:38La Florida, La Serena AirportLa Florida, La Serena Airport10:36Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 09/12/2025 09:38:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 09/12/2025 10:36:00. 50 Economy ticket for £74 per person are available. Travel duration is 0h 58m
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Sky Airline1h 4m011:41La Florida, La Serena AirportLa Florida, La Serena Airport12:45Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 09/12/2025 11:41:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 09/12/2025 12:45:00. 50 Economy ticket for £76 per person are available. Travel duration is 1h 4m
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Sky Airline1h 4m013:20La Florida, La Serena AirportLa Florida, La Serena Airport14:24Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 09/12/2025 13:20:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 09/12/2025 14:24:00. 50 Economy ticket for £76 per person are available. Travel duration is 1h 4m
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LAN Perú0h 57m020:45La Florida, La Serena AirportLa Florida, La Serena Airport21:42Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 09/12/2025 20:45:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 09/12/2025 21:42:00. 50 Economy ticket for £82 per person are available. Travel duration is 0h 57m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Buses Romani6h 15m000:45La SerenaCentral Coach Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Central Coach Station, La Serena (Chile) at 10/12/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 10/12/2025 07:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 15m
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Cikbus Elité7h 0m009:30La SerenaCentral Coach Station16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 10/12/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 10/12/2025 16:30:00. 50 Business ticket for £7 per person are available. Travel duration is 7h 0m
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Condor Bus6h 30m003:15La SerenaCentral Coach Station09:45Santiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Central Coach Station, La Serena (Chile) at 10/12/2025 03:15:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 10/12/2025 09:45:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 30m
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Turbus6h 30m003:15La SerenaAvda. Fco de Aguirre Station09:45Santiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 10/12/2025 03:15:00 to Terminal Alameda, Santiago, RM (Chile) arriving at 10/12/2025 09:45:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 30m
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Cormar Bus6h 20m011:50La SerenaCentral Coach Station18:10Santiago, RMTerminal San Borja0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 10/12/2025 11:50:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 10/12/2025 18:10:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 20m
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Sky Airline1h 4m010:47La Florida, La Serena AirportLa Florida, La Serena Airport11:51Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 10/12/2025 10:47:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 10/12/2025 11:51:00. 50 Economy ticket for £58 per person are available. Travel duration is 1h 4m
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LAN Perú0h 58m009:40La Florida, La Serena AirportLa Florida, La Serena Airport10:38Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 10/12/2025 09:40:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 10/12/2025 10:38:00. 50 Economy ticket for £63 per person are available. Travel duration is 0h 58m
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LAN Perú0h 58m012:09La Florida, La Serena AirportLa Florida, La Serena Airport13:07Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 10/12/2025 12:09:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 10/12/2025 13:07:00. 50 Economy ticket for £82 per person are available. Travel duration is 0h 58m
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LAN Airlines0h 57m015:32La Florida, La Serena AirportLa Florida, La Serena Airport16:29Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 10/12/2025 15:32:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 10/12/2025 16:29:00. 50 Economy ticket for £82 per person are available. Travel duration is 0h 57m
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Sky Airline1h 4m021:34La Florida, La Serena AirportLa Florida, La Serena Airport22:38Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 10/12/2025 21:34:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 10/12/2025 22:38:00. 50 Economy ticket for £127 per person are available. Travel duration is 1h 4m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
What are the fastest trips from La Serena to Santiago, RM?
You can get to Santiago, RM from La Serena in just 0h 57m with a Flight from LAN Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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LAN Perú0h 58m011:50La Florida, La Serena AirportLa Florida, La Serena Airport12:48Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/12/2025 11:50:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/12/2025 12:48:00. 50 Economy ticket for £83 per person are available. Travel duration is 0h 58m
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LAN Perú0h 58m009:40La Florida, La Serena AirportLa Florida, La Serena Airport10:38Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/12/2025 09:40:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/12/2025 10:38:00. 50 Economy ticket for £133 per person are available. Travel duration is 0h 58m
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JetSmart0h 59m012:59La Florida, La Serena AirportLa Florida, La Serena Airport13:58Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/12/2025 12:59:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/12/2025 13:58:00. 50 Economy ticket for £89 per person are available. Travel duration is 0h 59m
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Sky Airline1h 4m011:11La Florida, La Serena AirportLa Florida, La Serena Airport12:15Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/12/2025 11:11:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/12/2025 12:15:00. 50 Economy ticket for £103 per person are available. Travel duration is 1h 4m
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Sky Airline1h 4m019:53La Florida, La Serena AirportLa Florida, La Serena Airport20:57Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/12/2025 19:53:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/12/2025 20:57:00. 50 Economy ticket for £123 per person are available. Travel duration is 1h 4m
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Pullman Bus6h 0m004:30La SerenaCentral Coach Station10:30Santiago, RMTerminal San Borja0BusinessA Bus from Pullman Bus goes from Central Coach Station, La Serena (Chile) at 04/12/2025 04:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/12/2025 10:30:00. 50 Business ticket for £10 per person are available. Travel duration is 6h 0m
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FlixBus6h 5m006:00La SerenaCentral Coach Station12:05Santiago, RMTerminal San Borja0Premium EconomyA Bus from FlixBus goes from Central Coach Station, La Serena (Chile) at 04/12/2025 06:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/12/2025 12:05:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 5m
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Pullman San Andres6h 10m007:50La SerenaCentral Coach Station14:00Santiago, RMTerminal San Borja0First ClassA Bus from Pullman San Andres goes from Central Coach Station, La Serena (Chile) at 04/12/2025 07:50:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/12/2025 14:00:00. 50 First Class ticket for £10 per person are available. Travel duration is 6h 10m
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Buses Romani6h 15m000:45La SerenaCentral Coach Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Central Coach Station, La Serena (Chile) at 04/12/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 04/12/2025 07:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 15m
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Cikbus Elité7h 0m009:30La SerenaCentral Coach Station16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 04/12/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/12/2025 16:30:00. 50 Business ticket for £7 per person are available. Travel duration is 7h 0m
Fastest Flights Thursday
Fastest Buses Thursday
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LAN Airlines0h 57m022:25La Florida, La Serena AirportLa Florida, La Serena Airport23:22Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/12/2025 22:25:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/12/2025 23:22:00. 50 Economy ticket for £60 per person are available. Travel duration is 0h 57m
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LAN Perú0h 58m012:34La Florida, La Serena AirportLa Florida, La Serena Airport13:32Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/12/2025 12:34:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/12/2025 13:32:00. 50 Economy ticket for £48 per person are available. Travel duration is 0h 58m
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JetSmart0h 59m013:08La Florida, La Serena AirportLa Florida, La Serena Airport14:07Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/12/2025 13:08:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/12/2025 14:07:00. 50 Economy ticket for £59 per person are available. Travel duration is 0h 59m
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Sky Airline1h 4m018:16La Florida, La Serena AirportLa Florida, La Serena Airport19:20Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/12/2025 18:16:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/12/2025 19:20:00. 50 Economy ticket for £68 per person are available. Travel duration is 1h 4m
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Sky Airline1h 4m020:04La Florida, La Serena AirportLa Florida, La Serena Airport21:08Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/12/2025 20:04:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/12/2025 21:08:00. 50 Economy ticket for £68 per person are available. Travel duration is 1h 4m
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Serena Mar6h 0m010:00La SerenaCentral Coach Station16:00Santiago, RMTerminal San Borja0First ClassA Bus from Serena Mar goes from Central Coach Station, La Serena (Chile) at 05/12/2025 10:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/12/2025 16:00:00. 50 First Class ticket for £10 per person are available. Travel duration is 6h 0m
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FlixBus6h 5m006:00La SerenaCentral Coach Station12:05Santiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Central Coach Station, La Serena (Chile) at 05/12/2025 06:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/12/2025 12:05:00. 50 Economy ticket for £11 per person are available. Travel duration is 6h 5m
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Cormar Bus6h 40m000:15La SerenaCentral Coach Station06:55Santiago, RMTerminal San Borja0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 05/12/2025 00:15:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/12/2025 06:55:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 40m
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Condor Bus6h 50m003:15La SerenaCentral Coach Station10:05Santiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Central Coach Station, La Serena (Chile) at 05/12/2025 03:15:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/12/2025 10:05:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 50m
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Cikbus Elité7h 0m009:30La SerenaCentral Coach Station16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 05/12/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/12/2025 16:30:00. 50 Business ticket for £10 per person are available. Travel duration is 7h 0m
Fastest Flights Friday
Fastest Buses Friday
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LAN Perú0h 57m019:45La Florida, La Serena AirportLa Florida, La Serena Airport20:42Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 06/12/2025 19:45:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 06/12/2025 20:42:00. 50 Economy ticket for £82 per person are available. Travel duration is 0h 57m
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LAN Perú0h 58m009:46La Florida, La Serena AirportLa Florida, La Serena Airport10:44Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 06/12/2025 09:46:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 06/12/2025 10:44:00. 50 Economy ticket for £83 per person are available. Travel duration is 0h 58m
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JetSmart0h 59m010:27La Florida, La Serena AirportLa Florida, La Serena Airport11:26Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 06/12/2025 10:27:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 06/12/2025 11:26:00. 50 Economy ticket for £75 per person are available. Travel duration is 0h 59m
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Sky Airline1h 4m011:11La Florida, La Serena AirportLa Florida, La Serena Airport12:15Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 06/12/2025 11:11:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 06/12/2025 12:15:00. 50 Economy ticket for £77 per person are available. Travel duration is 1h 4m
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FlixBus6h 5m014:15La SerenaCentral Coach Station20:20Santiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Central Coach Station, La Serena (Chile) at 06/12/2025 14:15:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 06/12/2025 20:20:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 5m
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Cormar Bus6h 10m013:20La SerenaCentral Coach Station19:30Santiago, RMTerminal San Borja0First ClassA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 06/12/2025 13:20:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 06/12/2025 19:30:00. 50 First Class ticket for £11 per person are available. Travel duration is 6h 10m
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Buses Romani6h 15m000:45La SerenaCentral Coach Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Central Coach Station, La Serena (Chile) at 06/12/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 06/12/2025 07:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 15m
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Condor Bus6h 15m016:50La SerenaCentral Coach Station23:05Santiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Central Coach Station, La Serena (Chile) at 06/12/2025 16:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 06/12/2025 23:05:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 6h 15m
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Turbus6h 25m012:00La SerenaAvda. Fco de Aguirre Station18:25Santiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 06/12/2025 12:00:00 to Terminal Alameda, Santiago, RM (Chile) arriving at 06/12/2025 18:25:00. 50 Premium Economy ticket for £12 per person are available. Travel duration is 6h 25m
Fastest Flights Saturday
Fastest Buses Saturday
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LAN Airlines0h 57m014:00La Florida, La Serena AirportLa Florida, La Serena Airport14:57Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 07/12/2025 14:00:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 07/12/2025 14:57:00. 50 Economy ticket for £53 per person are available. Travel duration is 0h 57m
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LAN Airlines0h 57m015:40La Florida, La Serena AirportLa Florida, La Serena Airport16:37Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 07/12/2025 15:40:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 07/12/2025 16:37:00. 50 Economy ticket for £58 per person are available. Travel duration is 0h 57m
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LAN Perú0h 58m009:40La Florida, La Serena AirportLa Florida, La Serena Airport10:38Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 07/12/2025 09:40:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 07/12/2025 10:38:00. 50 Economy ticket for £48 per person are available. Travel duration is 0h 58m
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JetSmart0h 59m010:44La Florida, La Serena AirportLa Florida, La Serena Airport11:43Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 07/12/2025 10:44:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 07/12/2025 11:43:00. 50 Economy ticket for £47 per person are available. Travel duration is 0h 59m
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Sky Airline1h 4m011:01La Florida, La Serena AirportLa Florida, La Serena Airport12:05Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 07/12/2025 11:01:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 07/12/2025 12:05:00. 50 Economy ticket for £46 per person are available. Travel duration is 1h 4m
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Buses Romani6h 0m009:00La SerenaCentral Coach Station15:00Santiago, RMTerminal San Borja0BusinessA Bus from Buses Romani goes from Central Coach Station, La Serena (Chile) at 07/12/2025 09:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 07/12/2025 15:00:00. 50 Business ticket for £8 per person are available. Travel duration is 6h 0m
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Serena Mar6h 0m010:00La SerenaCentral Coach Station16:00Santiago, RMTerminal San Borja0First ClassA Bus from Serena Mar goes from Central Coach Station, La Serena (Chile) at 07/12/2025 10:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 07/12/2025 16:00:00. 50 First Class ticket for £10 per person are available. Travel duration is 6h 0m
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FlixBus6h 5m015:30La SerenaCentral Coach Station21:35Santiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Central Coach Station, La Serena (Chile) at 07/12/2025 15:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 07/12/2025 21:35:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 5m
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Condor Bus6h 35m001:45La SerenaCentral Coach Station08:20Santiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Central Coach Station, La Serena (Chile) at 07/12/2025 01:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 07/12/2025 08:20:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 6h 35m
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Cikbus Elité7h 0m009:30La SerenaCentral Coach Station16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 07/12/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 07/12/2025 16:30:00. 50 Business ticket for £10 per person are available. Travel duration is 7h 0m
Fastest Flights Sunday
Fastest Buses Sunday
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LAN Perú0h 57m020:35La Florida, La Serena AirportLa Florida, La Serena Airport21:32Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 08/12/2025 20:35:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 08/12/2025 21:32:00. 50 Economy ticket for £118 per person are available. Travel duration is 0h 57m
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LAN Airlines0h 57m016:58La Florida, La Serena AirportLa Florida, La Serena Airport17:55Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 08/12/2025 16:58:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 08/12/2025 17:55:00. 50 Economy ticket for £121 per person are available. Travel duration is 0h 57m
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LAN Airlines0h 58m013:32La Florida, La Serena AirportLa Florida, La Serena Airport14:30Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 08/12/2025 13:32:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 08/12/2025 14:30:00. 50 Economy ticket for £115 per person are available. Travel duration is 0h 58m
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JetSmart0h 59m012:35La Florida, La Serena AirportLa Florida, La Serena Airport13:34Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 08/12/2025 12:35:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 08/12/2025 13:34:00. 50 Economy ticket for £76 per person are available. Travel duration is 0h 59m
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Sky Airline1h 4m012:19La Florida, La Serena AirportLa Florida, La Serena Airport13:23Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 08/12/2025 12:19:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 08/12/2025 13:23:00. 50 Economy ticket for £112 per person are available. Travel duration is 1h 4m
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Serena Mar6h 0m010:00La SerenaCentral Coach Station16:00Santiago, RMTerminal San Borja0First ClassA Bus from Serena Mar goes from Central Coach Station, La Serena (Chile) at 08/12/2025 10:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 08/12/2025 16:00:00. 50 First Class ticket for £10 per person are available. Travel duration is 6h 0m
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Cormar Bus6h 10m013:20La SerenaCentral Coach Station19:30Santiago, RMTerminal San Borja0First ClassA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 08/12/2025 13:20:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 08/12/2025 19:30:00. 50 First Class ticket for £12 per person are available. Travel duration is 6h 10m
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Buses Romani6h 15m000:45La SerenaCentral Coach Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Central Coach Station, La Serena (Chile) at 08/12/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 08/12/2025 07:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 15m
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Turbus6h 15m002:30La SerenaAvda. Fco de Aguirre Station08:45Santiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 08/12/2025 02:30:00 to Terminal Alameda, Santiago, RM (Chile) arriving at 08/12/2025 08:45:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 15m
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Cikbus Elité7h 0m009:30La SerenaCentral Coach Station16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 08/12/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 08/12/2025 16:30:00. 50 Business ticket for £10 per person are available. Travel duration is 7h 0m
Fastest Flights Monday
Fastest Buses Monday
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LAN Perú0h 57m020:45La Florida, La Serena AirportLa Florida, La Serena Airport21:42Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 09/12/2025 20:45:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 09/12/2025 21:42:00. 50 Economy ticket for £82 per person are available. Travel duration is 0h 57m
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LAN Perú0h 58m009:38La Florida, La Serena AirportLa Florida, La Serena Airport10:36Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 09/12/2025 09:38:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 09/12/2025 10:36:00. 50 Economy ticket for £74 per person are available. Travel duration is 0h 58m
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JetSmart0h 59m010:30La Florida, La Serena AirportLa Florida, La Serena Airport11:29Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 09/12/2025 10:30:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 09/12/2025 11:29:00. 50 Economy ticket for £67 per person are available. Travel duration is 0h 59m
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Sky Airline1h 4m011:41La Florida, La Serena AirportLa Florida, La Serena Airport12:45Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 09/12/2025 11:41:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 09/12/2025 12:45:00. 50 Economy ticket for £76 per person are available. Travel duration is 1h 4m
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Sky Airline1h 4m013:20La Florida, La Serena AirportLa Florida, La Serena Airport14:24Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 09/12/2025 13:20:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 09/12/2025 14:24:00. 50 Economy ticket for £76 per person are available. Travel duration is 1h 4m
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Buses Romani6h 0m009:00La SerenaCentral Coach Station15:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Central Coach Station, La Serena (Chile) at 09/12/2025 09:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 09/12/2025 15:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 0m
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Turbus6h 5m006:55La SerenaAvda. Fco de Aguirre Station13:00Santiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 09/12/2025 06:55:00 to Terminal Alameda, Santiago, RM (Chile) arriving at 09/12/2025 13:00:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 5m
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Cormar Bus6h 10m023:50La SerenaCentral Coach Station06:00Santiago, RMTerminal San Borja0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 09/12/2025 23:50:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 10/12/2025 06:00:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 10m
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Condor Bus6h 15m016:50La SerenaCentral Coach Station23:05Santiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Central Coach Station, La Serena (Chile) at 09/12/2025 16:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 09/12/2025 23:05:00. 50 Premium Economy ticket for £11 per person are available. Travel duration is 6h 15m
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Cikbus Elité7h 0m009:30La SerenaCentral Coach Station16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 09/12/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 09/12/2025 16:30:00. 50 Business ticket for £10 per person are available. Travel duration is 7h 0m
Fastest Flights Tuesday
Fastest Buses Tuesday
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LAN Airlines0h 57m015:32La Florida, La Serena AirportLa Florida, La Serena Airport16:29Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 10/12/2025 15:32:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 10/12/2025 16:29:00. 50 Economy ticket for £82 per person are available. Travel duration is 0h 57m
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LAN Perú0h 58m009:40La Florida, La Serena AirportLa Florida, La Serena Airport10:38Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 10/12/2025 09:40:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 10/12/2025 10:38:00. 50 Economy ticket for £63 per person are available. Travel duration is 0h 58m
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LAN Perú0h 58m012:09La Florida, La Serena AirportLa Florida, La Serena Airport13:07Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 10/12/2025 12:09:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 10/12/2025 13:07:00. 50 Economy ticket for £82 per person are available. Travel duration is 0h 58m
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Sky Airline1h 4m010:47La Florida, La Serena AirportLa Florida, La Serena Airport11:51Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 10/12/2025 10:47:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 10/12/2025 11:51:00. 50 Economy ticket for £58 per person are available. Travel duration is 1h 4m
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Sky Airline1h 4m021:34La Florida, La Serena AirportLa Florida, La Serena Airport22:38Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 10/12/2025 21:34:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 10/12/2025 22:38:00. 50 Economy ticket for £127 per person are available. Travel duration is 1h 4m
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Buses Romani6h 15m000:45La SerenaCentral Coach Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Central Coach Station, La Serena (Chile) at 10/12/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 10/12/2025 07:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 15m
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Cormar Bus6h 20m011:50La SerenaCentral Coach Station18:10Santiago, RMTerminal San Borja0Premium EconomyA Bus from Cormar Bus goes from Central Coach Station, La Serena (Chile) at 10/12/2025 11:50:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 10/12/2025 18:10:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 20m
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Condor Bus6h 30m003:15La SerenaCentral Coach Station09:45Santiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Central Coach Station, La Serena (Chile) at 10/12/2025 03:15:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 10/12/2025 09:45:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 30m
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Turbus6h 30m003:15La SerenaAvda. Fco de Aguirre Station09:45Santiago, RMTerminal Alameda0Premium EconomyA Bus from Turbus goes from Avda. Fco de Aguirre Station, La Serena (Chile) at 10/12/2025 03:15:00 to Terminal Alameda, Santiago, RM (Chile) arriving at 10/12/2025 09:45:00. 50 Premium Economy ticket for £8 per person are available. Travel duration is 6h 30m
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Cikbus Elité7h 0m009:30La SerenaCentral Coach Station16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Central Coach Station, La Serena (Chile) at 10/12/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 10/12/2025 16:30:00. 50 Business ticket for £7 per person are available. Travel duration is 7h 0m
Fastest Flights Wednesday
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from La Serena to Santiago, RM
What are the most popular stations in La Serena and Santiago, RM?
In La Serena, you will usually depart from Avda. Fco de Aguirre Station, Central Coach Station or El Sto, 1060, while in Santiago, RM you will be arriving at Terminal Alameda, Terminal San Borja or Sur Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Santiago, RM from La Serena? With 9 connections between 13 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between La Serena and Santiago, RM, you can pay as low as £7 with a Bus from Buses Romani.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from LAN Airlines: you will get to Santiago, RM in just 0h 57m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting La Serena and Santiago, RM are LAN Perú, Sky Airline and Buses Romani, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in La Serena and Santiago, RM is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from La Florida, La Serena Airport or to Lo Prado, and look at flights from La Florida, La Serena Airport, and landing at Santiago de Chile Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from La Serena to Santiago, RM?
The most popular companies between La Serena and Santiago, RM, are LAN Perú, Sky Airline and Buses Romani. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Buses Romani, Cikbus Elité, Condor Bus and 6 more.
Airlines: LAN Perú, Sky Airline, JetSmart and 1 more.
All you need to know when you travel from La Serena to Santiago, RM
Check all information on comfort and services on all modes of transports from La Serena to Santiago, RM. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from La Serena to Santiago, RM
How can I reach Santiago, RM from La Serena?
Every day, there are on average 9 connections between Bus and Flight, with which you can get to Santiago, RM from La Serena.
How far is Santiago, RM from La Serena?
The distance between La Serena and Santiago, RM is 397.3 km.
What is the most ecofriendly mode of transport between La Serena and Santiago, RM?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 11 kgs of CO2, a train 14 kgs, a car 68 kgs, and a flight 98 kgs.
What is the cheapest mode of transport from La Serena to Santiago, RM?
You can get to Santiago, RM with just £7 by taking a Bus from Buses Romani.
What is the fastest way to get from La Serena to Santiago, RM?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Santiago, RM in just 0h 57m with a Flight from LAN Airlines.
More routes to La Serena and to Santiago, RM
Looking for more options? Here you can see the most popular routes to La Serena and to Santiago, RM. Simply click on a connection, and you’ll find all the details about the route!
- Trips to La Serena
- Antofagasta to La Serena
- Arica, AP to La Serena
- Calama to La Serena
- Concepción to La Serena
- Iquique to La Serena
- Mendoza to La Serena
- San Juan, SJ to La Serena
- Santiago, RM to La Serena
- Trips to Santiago, RM
- Antofagasta to Santiago, RM
- Arica, AP to Santiago, RM
- Buenos Aires to Santiago, RM
- Calama to Santiago, RM
- Concepción to Santiago, RM
- Copiapó to Santiago, RM
- Coquimbo to Santiago, RM
- Coronel to Santiago, RM
- Freire to Santiago, RM
- Iquique to Santiago, RM
- Los Ángeles, BI to Santiago, RM
- Mendoza to Santiago, RM
- Osorno, LL to Santiago, RM
- Puerto Montt to Santiago, RM
- Puerto Varas to Santiago, RM
- Santiago de Chile Airport to Santiago, RM
- São Paulo to Santiago, RM
- Temuco to Santiago, RM
- Valdivia to Santiago, RM
- Valparaíso (CL) to Santiago, RM
- Viña del Mar to Santiago, RM

