What is the best way to travel from La Serena to Santiago, RM?
Looking for a trip? Check and compare all the available Buses and Flights to Santiago, RM from La Serena. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 13 available companies to find your perfect trip!
What is the cheapest way to reach Santiago, RM from La Serena?
You can reach Santiago, RM with just £5 by taking a Bus from Pluss Chile, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Pluss Chile6h 30m002:45La SerenaBus Station09:15Santiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 29/06/2025 02:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 29/06/2025 09:15:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 30m
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Cikbus Elité6h 0m017:30La SerenaBus Stop23:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 29/06/2025 17:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 29/06/2025 23:30:00. 50 Business ticket for £7 per person are available. Travel duration is 6h 0m
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Buses Romani6h 0m009:00La SerenaBus Station15:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 29/06/2025 09:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 29/06/2025 15:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 0m
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Condor Bus6h 35m001:45La SerenaBus Station08:20Santiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Bus Station, La Serena (Chile) at 29/06/2025 01:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 29/06/2025 08:20:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 35m
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Pullman Bus6h 0m000:45La SerenaEl Sto, 106006:45Santiago, RMTerminal San Borja0First ClassA Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 29/06/2025 00:45:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 29/06/2025 06:45:00. 50 First Class ticket for £10 per person are available. Travel duration is 6h 0m
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LAN Perú0h 56m012:14La Florida, La Serena AirportLa Florida, La Serena Airport13:10Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 29/06/2025 12:14:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 29/06/2025 13:10:00. 50 Economy ticket for £44 per person are available. Travel duration is 0h 56m
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JetSmart0h 58m021:18La Florida, La Serena AirportLa Florida, La Serena Airport22:16Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 29/06/2025 21:18:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 29/06/2025 22:16:00. 50 Economy ticket for £46 per person are available. Travel duration is 0h 58m
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LAN Perú0h 56m015:15La Florida, La Serena AirportLa Florida, La Serena Airport16:11Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 29/06/2025 15:15:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 29/06/2025 16:11:00. 50 Economy ticket for £51 per person are available. Travel duration is 0h 56m
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JetSmart0h 58m015:46La Florida, La Serena AirportLa Florida, La Serena Airport16:44Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 29/06/2025 15:46:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 29/06/2025 16:44:00. 50 Economy ticket for £56 per person are available. Travel duration is 0h 58m
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LAN Airlines0h 56m016:18La Florida, La Serena AirportLa Florida, La Serena Airport17:14Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 29/06/2025 16:18:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 29/06/2025 17:14:00. 50 Economy ticket for £65 per person are available. Travel duration is 0h 56m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Pluss Chile6h 40m000:05La SerenaBus Station06:45Santiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 30/06/2025 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 30/06/2025 06:45:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 40m
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Buses Romani6h 0m009:00La SerenaBus Station15:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 30/06/2025 09:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 30/06/2025 15:00:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 0m
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Cikbus Elité7h 15m014:05La SerenaBus Stop21:20Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 30/06/2025 14:05:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 30/06/2025 21:20:00. 50 Business ticket for £7 per person are available. Travel duration is 7h 15m
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Nueva Andimar Vip6h 10m000:50La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 30/06/2025 00:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 30/06/2025 07:00:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 10m
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FlixBus5h 59m018:00La SerenaBus Station23:59Santiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Bus Station, La Serena (Chile) at 30/06/2025 18:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 30/06/2025 23:59:00. 50 Economy ticket for £9 per person are available. Travel duration is 5h 59m
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LAN Perú0h 56m013:18La Florida, La Serena AirportLa Florida, La Serena Airport14:14Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 30/06/2025 13:18:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 30/06/2025 14:14:00. 50 Economy ticket for £42 per person are available. Travel duration is 0h 56m
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JetSmart0h 58m011:15La Florida, La Serena AirportLa Florida, La Serena Airport12:13Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 30/06/2025 11:15:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 30/06/2025 12:13:00. 50 Economy ticket for £46 per person are available. Travel duration is 0h 58m
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LAN Perú0h 56m020:45La Florida, La Serena AirportLa Florida, La Serena Airport21:41Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 30/06/2025 20:45:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 30/06/2025 21:41:00. 50 Economy ticket for £49 per person are available. Travel duration is 0h 56m
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Sky Airline1h 1m012:14La Florida, La Serena AirportLa Florida, La Serena Airport13:15Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 30/06/2025 12:14:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 30/06/2025 13:15:00. 50 Economy ticket for £53 per person are available. Travel duration is 1h 1m
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Sky Airline1h 1m018:05La Florida, La Serena AirportLa Florida, La Serena Airport19:06Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 30/06/2025 18:05:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 30/06/2025 19:06:00. 50 Economy ticket for £53 per person are available. Travel duration is 1h 1m
Cheapest Buses Monday
Cheapest Flights Monday
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Pluss Chile7h 15m009:05La SerenaBus Station16:20Santiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 01/07/2025 09:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 01/07/2025 16:20:00. 50 Premium Economy ticket for £5 per person are available. Travel duration is 7h 15m
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Buses Romani6h 15m000:45La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 01/07/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 01/07/2025 07:00:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 15m
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Cikbus Elité7h 0m009:30La SerenaBus Stop16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 01/07/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 01/07/2025 16:30:00. 50 Business ticket for £7 per person are available. Travel duration is 7h 0m
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FlixBus6h 5m006:00La SerenaBus Station12:05Santiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Bus Station, La Serena (Chile) at 01/07/2025 06:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 01/07/2025 12:05:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 5m
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Cormar Bus6h 30m007:45La SerenaBus Station14:15Santiago, RMTerminal San Borja0First ClassA Bus from Cormar Bus goes from Bus Station, La Serena (Chile) at 01/07/2025 07:45:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 01/07/2025 14:15:00. 50 First Class ticket for £10 per person are available. Travel duration is 6h 30m
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LAN Perú0h 57m012:30La Florida, La Serena AirportLa Florida, La Serena Airport13:27Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 01/07/2025 12:30:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 01/07/2025 13:27:00. 50 Economy ticket for £56 per person are available. Travel duration is 0h 57m
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JetSmart0h 58m011:08La Florida, La Serena AirportLa Florida, La Serena Airport12:06Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 01/07/2025 11:08:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 01/07/2025 12:06:00. 50 Economy ticket for £56 per person are available. Travel duration is 0h 58m
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LAN Perú0h 57m009:45La Florida, La Serena AirportLa Florida, La Serena Airport10:42Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 01/07/2025 09:45:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 01/07/2025 10:42:00. 50 Economy ticket for £65 per person are available. Travel duration is 0h 57m
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Sky Airline1h 1m012:23La Florida, La Serena AirportLa Florida, La Serena Airport13:24Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 01/07/2025 12:23:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 01/07/2025 13:24:00. 50 Economy ticket for £73 per person are available. Travel duration is 1h 1m
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JetSmart8h 30m010:05La Florida, La Serena AirportLa Florida, La Serena Airport18:35Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 01/07/2025 10:05:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 01/07/2025 18:35:00. 50 Economy ticket for £83 per person are available. Travel duration is 8h 30m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Pluss Chile6h 40m000:05La SerenaBus Station06:45Santiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 02/07/2025 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 02/07/2025 06:45:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 40m
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Cikbus Elité6h 0m016:30La SerenaBus Stop22:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 02/07/2025 16:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 02/07/2025 22:30:00. 50 Business ticket for £7 per person are available. Travel duration is 6h 0m
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FlixBus6h 5m006:00La SerenaBus Station12:05Santiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Bus Station, La Serena (Chile) at 02/07/2025 06:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 02/07/2025 12:05:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 5m
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Cormar Bus6h 30m010:10La SerenaBus Station16:40Santiago, RMTerminal San Borja0First ClassA Bus from Cormar Bus goes from Bus Station, La Serena (Chile) at 02/07/2025 10:10:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 02/07/2025 16:40:00. 50 First Class ticket for £11 per person are available. Travel duration is 6h 30m
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Pullman San Andres7h 15m011:00La SerenaBus Station18:15Santiago, RMTerminal San Borja0First ClassA Bus from Pullman San Andres goes from Bus Station, La Serena (Chile) at 02/07/2025 11:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 02/07/2025 18:15:00. 50 First Class ticket for £12 per person are available. Travel duration is 7h 15m
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LAN Perú0h 57m012:09La Florida, La Serena AirportLa Florida, La Serena Airport13:06Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 02/07/2025 12:09:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 02/07/2025 13:06:00. 50 Economy ticket for £65 per person are available. Travel duration is 0h 57m
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Sky Airline1h 1m021:31La Florida, La Serena AirportLa Florida, La Serena Airport22:32Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 02/07/2025 21:31:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 02/07/2025 22:32:00. 50 Economy ticket for £72 per person are available. Travel duration is 1h 1m
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LAN Perú0h 57m009:45La Florida, La Serena AirportLa Florida, La Serena Airport10:42Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 02/07/2025 09:45:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 02/07/2025 10:42:00. 50 Economy ticket for £76 per person are available. Travel duration is 0h 57m
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LAN Perú0h 57m021:02La Florida, La Serena AirportLa Florida, La Serena Airport21:59Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 02/07/2025 21:02:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 02/07/2025 21:59:00. 50 Economy ticket for £113 per person are available. Travel duration is 0h 57m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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Pluss Chile6h 40m000:05La SerenaBus Station06:45Santiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 03/07/2025 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 03/07/2025 06:45:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 40m
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Buses Romani6h 15m000:45La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 03/07/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 03/07/2025 07:00:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 15m
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Cikbus Elité7h 0m009:30La SerenaBus Stop16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 03/07/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 03/07/2025 16:30:00. 50 Business ticket for £7 per person are available. Travel duration is 7h 0m
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Nueva Andimar Vip6h 10m000:50La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 03/07/2025 00:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 03/07/2025 07:00:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Buses Paravias6h 40m023:30La SerenaBus Stop06:10Santiago, RMTerminal San Borja0BusinessA Bus from Buses Paravias goes from Bus Stop, La Serena (Chile) at 03/07/2025 23:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/07/2025 06:10:00. 50 Business ticket for £10 per person are available. Travel duration is 6h 40m
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JetSmart0h 58m009:44La Florida, La Serena AirportLa Florida, La Serena Airport10:42Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 03/07/2025 09:44:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 03/07/2025 10:42:00. 50 Economy ticket for £39 per person are available. Travel duration is 0h 58m
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Sky Airline1h 1m011:05La Florida, La Serena AirportLa Florida, La Serena Airport12:06Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 03/07/2025 11:05:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 03/07/2025 12:06:00. 50 Economy ticket for £41 per person are available. Travel duration is 1h 1m
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Sky Airline1h 1m012:05La Florida, La Serena AirportLa Florida, La Serena Airport13:06Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 03/07/2025 12:05:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 03/07/2025 13:06:00. 50 Economy ticket for £41 per person are available. Travel duration is 1h 1m
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LAN Perú0h 57m012:00La Florida, La Serena AirportLa Florida, La Serena Airport12:57Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 03/07/2025 12:00:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 03/07/2025 12:57:00. 50 Economy ticket for £51 per person are available. Travel duration is 0h 57m
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LAN Perú0h 57m009:40La Florida, La Serena AirportLa Florida, La Serena Airport10:37Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 03/07/2025 09:40:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 03/07/2025 10:37:00. 50 Economy ticket for £65 per person are available. Travel duration is 0h 57m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Pluss Chile6h 40m000:05La SerenaBus Station06:45Santiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 04/07/2025 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 04/07/2025 06:45:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 40m
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Buses Romani6h 15m000:45La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 04/07/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 04/07/2025 07:00:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 15m
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Nueva Andimar Vip6h 10m000:50La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 04/07/2025 00:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 04/07/2025 07:00:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Cormar Bus6h 50m015:30La SerenaBus Station22:20Santiago, RMTerminal San Borja0First ClassA Bus from Cormar Bus goes from Bus Station, La Serena (Chile) at 04/07/2025 15:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/07/2025 22:20:00. 50 First Class ticket for £9 per person are available. Travel duration is 6h 50m
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Cikbus Elité7h 20m001:10La SerenaBus Station08:30Santiago, RMSur Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Bus Station, La Serena (Chile) at 04/07/2025 01:10:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 04/07/2025 08:30:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 7h 20m
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JetSmart0h 58m011:15La Florida, La Serena AirportLa Florida, La Serena Airport12:13Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/07/2025 11:15:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/07/2025 12:13:00. 50 Economy ticket for £42 per person are available. Travel duration is 0h 58m
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Sky Airline1h 1m011:58La Florida, La Serena AirportLa Florida, La Serena Airport12:59Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/07/2025 11:58:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/07/2025 12:59:00. 50 Economy ticket for £42 per person are available. Travel duration is 1h 1m
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LAN Airlines0h 57m022:11La Florida, La Serena AirportLa Florida, La Serena Airport23:08Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/07/2025 22:11:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/07/2025 23:08:00. 50 Economy ticket for £42 per person are available. Travel duration is 0h 57m
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LAN Perú0h 57m020:52La Florida, La Serena AirportLa Florida, La Serena Airport21:49Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/07/2025 20:52:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/07/2025 21:49:00. 50 Economy ticket for £43 per person are available. Travel duration is 0h 57m
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Sky Airline1h 1m018:52La Florida, La Serena AirportLa Florida, La Serena Airport19:53Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/07/2025 18:52:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/07/2025 19:53:00. 50 Economy ticket for £47 per person are available. Travel duration is 1h 1m
Cheapest Buses Friday
Cheapest Flights Friday
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Pluss Chile6h 30m000:05La SerenaBus Station06:35Santiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 05/07/2025 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/07/2025 06:35:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 30m
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Buses Romani6h 15m000:45La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 05/07/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/07/2025 07:00:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 15m
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Nueva Andimar Vip6h 10m000:50La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 05/07/2025 00:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/07/2025 07:00:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Turbus6h 50m003:15La SerenaBus Station10:05Santiago, RMTerminal San Borja0Premium EconomyA Bus from Turbus goes from Bus Station, La Serena (Chile) at 05/07/2025 03:15:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/07/2025 10:05:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 50m
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Cikbus Elité7h 20m001:10La SerenaBus Station08:30Santiago, RMSur Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Bus Station, La Serena (Chile) at 05/07/2025 01:10:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/07/2025 08:30:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 7h 20m
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Sky Airline1h 1m017:34La Florida, La Serena AirportLa Florida, La Serena Airport18:35Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/07/2025 17:34:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/07/2025 18:35:00. 50 Economy ticket for £33 per person are available. Travel duration is 1h 1m
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Air China Cargo1h 1m017:34La Florida, La Serena AirportLa Florida, La Serena Airport18:35Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Air China Cargo goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/07/2025 17:34:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/07/2025 18:35:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 1m
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LAN Perú0h 57m009:50La Florida, La Serena AirportLa Florida, La Serena Airport10:47Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/07/2025 09:50:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/07/2025 10:47:00. 50 Economy ticket for £43 per person are available. Travel duration is 0h 57m
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LAN Perú0h 57m011:34La Florida, La Serena AirportLa Florida, La Serena Airport12:31Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/07/2025 11:34:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/07/2025 12:31:00. 50 Economy ticket for £49 per person are available. Travel duration is 0h 57m
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JetSmart0h 58m011:39La Florida, La Serena AirportLa Florida, La Serena Airport12:37Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/07/2025 11:39:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/07/2025 12:37:00. 50 Economy ticket for £57 per person are available. Travel duration is 0h 58m
Cheapest Buses Saturday
Cheapest Flights Saturday
What are the fastest trips from La Serena to Santiago, RM?
You can get to Santiago, RM from La Serena in just 0h 56m with a Flight from LAN Perú. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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LAN Perú0h 56m012:14La Florida, La Serena AirportLa Florida, La Serena Airport13:10Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 29/06/2025 12:14:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 29/06/2025 13:10:00. 50 Economy ticket for £44 per person are available. Travel duration is 0h 56m
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LAN Perú0h 56m015:15La Florida, La Serena AirportLa Florida, La Serena Airport16:11Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 29/06/2025 15:15:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 29/06/2025 16:11:00. 50 Economy ticket for £51 per person are available. Travel duration is 0h 56m
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LAN Airlines0h 56m016:18La Florida, La Serena AirportLa Florida, La Serena Airport17:14Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 29/06/2025 16:18:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 29/06/2025 17:14:00. 50 Economy ticket for £65 per person are available. Travel duration is 0h 56m
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JetSmart0h 58m021:18La Florida, La Serena AirportLa Florida, La Serena Airport22:16Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 29/06/2025 21:18:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 29/06/2025 22:16:00. 50 Economy ticket for £46 per person are available. Travel duration is 0h 58m
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JetSmart0h 58m015:46La Florida, La Serena AirportLa Florida, La Serena Airport16:44Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 29/06/2025 15:46:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 29/06/2025 16:44:00. 50 Economy ticket for £56 per person are available. Travel duration is 0h 58m
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Cikbus Elité6h 0m017:30La SerenaBus Stop23:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 29/06/2025 17:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 29/06/2025 23:30:00. 50 Business ticket for £7 per person are available. Travel duration is 6h 0m
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Buses Romani6h 0m009:00La SerenaBus Station15:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 29/06/2025 09:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 29/06/2025 15:00:00. 50 Premium Economy ticket for £7 per person are available. Travel duration is 6h 0m
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Pullman Bus6h 0m000:45La SerenaEl Sto, 106006:45Santiago, RMTerminal San Borja0First ClassA Bus from Pullman Bus goes from El Sto, 1060, La Serena (Chile) at 29/06/2025 00:45:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 29/06/2025 06:45:00. 50 First Class ticket for £10 per person are available. Travel duration is 6h 0m
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Pluss Chile6h 30m002:45La SerenaBus Station09:15Santiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 29/06/2025 02:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 29/06/2025 09:15:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 30m
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Condor Bus6h 35m001:45La SerenaBus Station08:20Santiago, RMSur Bus Station0Premium EconomyA Bus from Condor Bus goes from Bus Station, La Serena (Chile) at 29/06/2025 01:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 29/06/2025 08:20:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 35m
Fastest Flights Sunday
Fastest Buses Sunday
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LAN Perú0h 56m013:18La Florida, La Serena AirportLa Florida, La Serena Airport14:14Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 30/06/2025 13:18:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 30/06/2025 14:14:00. 50 Economy ticket for £42 per person are available. Travel duration is 0h 56m
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LAN Perú0h 56m020:45La Florida, La Serena AirportLa Florida, La Serena Airport21:41Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 30/06/2025 20:45:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 30/06/2025 21:41:00. 50 Economy ticket for £49 per person are available. Travel duration is 0h 56m
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JetSmart0h 58m011:15La Florida, La Serena AirportLa Florida, La Serena Airport12:13Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 30/06/2025 11:15:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 30/06/2025 12:13:00. 50 Economy ticket for £46 per person are available. Travel duration is 0h 58m
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Sky Airline1h 1m012:14La Florida, La Serena AirportLa Florida, La Serena Airport13:15Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 30/06/2025 12:14:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 30/06/2025 13:15:00. 50 Economy ticket for £53 per person are available. Travel duration is 1h 1m
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Sky Airline1h 1m018:05La Florida, La Serena AirportLa Florida, La Serena Airport19:06Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 30/06/2025 18:05:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 30/06/2025 19:06:00. 50 Economy ticket for £53 per person are available. Travel duration is 1h 1m
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FlixBus5h 59m018:00La SerenaBus Station23:59Santiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Bus Station, La Serena (Chile) at 30/06/2025 18:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 30/06/2025 23:59:00. 50 Economy ticket for £9 per person are available. Travel duration is 5h 59m
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Buses Romani6h 0m009:00La SerenaBus Station15:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 30/06/2025 09:00:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 30/06/2025 15:00:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 0m
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Nueva Andimar Vip6h 10m000:50La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 30/06/2025 00:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 30/06/2025 07:00:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Pluss Chile6h 40m000:05La SerenaBus Station06:45Santiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 30/06/2025 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 30/06/2025 06:45:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 40m
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Cikbus Elité7h 15m014:05La SerenaBus Stop21:20Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 30/06/2025 14:05:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 30/06/2025 21:20:00. 50 Business ticket for £7 per person are available. Travel duration is 7h 15m
Fastest Flights Monday
Fastest Buses Monday
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LAN Perú0h 57m012:30La Florida, La Serena AirportLa Florida, La Serena Airport13:27Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 01/07/2025 12:30:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 01/07/2025 13:27:00. 50 Economy ticket for £56 per person are available. Travel duration is 0h 57m
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LAN Perú0h 57m009:45La Florida, La Serena AirportLa Florida, La Serena Airport10:42Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 01/07/2025 09:45:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 01/07/2025 10:42:00. 50 Economy ticket for £65 per person are available. Travel duration is 0h 57m
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JetSmart0h 58m011:08La Florida, La Serena AirportLa Florida, La Serena Airport12:06Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 01/07/2025 11:08:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 01/07/2025 12:06:00. 50 Economy ticket for £56 per person are available. Travel duration is 0h 58m
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Sky Airline1h 1m012:23La Florida, La Serena AirportLa Florida, La Serena Airport13:24Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 01/07/2025 12:23:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 01/07/2025 13:24:00. 50 Economy ticket for £73 per person are available. Travel duration is 1h 1m
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JetSmart8h 30m010:05La Florida, La Serena AirportLa Florida, La Serena Airport18:35Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 01/07/2025 10:05:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 01/07/2025 18:35:00. 50 Economy ticket for £83 per person are available. Travel duration is 8h 30m
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FlixBus6h 5m006:00La SerenaBus Station12:05Santiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Bus Station, La Serena (Chile) at 01/07/2025 06:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 01/07/2025 12:05:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 5m
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Buses Romani6h 15m000:45La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 01/07/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 01/07/2025 07:00:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 15m
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Cormar Bus6h 30m007:45La SerenaBus Station14:15Santiago, RMTerminal San Borja0First ClassA Bus from Cormar Bus goes from Bus Station, La Serena (Chile) at 01/07/2025 07:45:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 01/07/2025 14:15:00. 50 First Class ticket for £10 per person are available. Travel duration is 6h 30m
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Cikbus Elité7h 0m009:30La SerenaBus Stop16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 01/07/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 01/07/2025 16:30:00. 50 Business ticket for £7 per person are available. Travel duration is 7h 0m
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Pluss Chile7h 15m009:05La SerenaBus Station16:20Santiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 01/07/2025 09:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 01/07/2025 16:20:00. 50 Premium Economy ticket for £5 per person are available. Travel duration is 7h 15m
Fastest Flights Tuesday
Fastest Buses Tuesday
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LAN Perú0h 57m012:09La Florida, La Serena AirportLa Florida, La Serena Airport13:06Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 02/07/2025 12:09:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 02/07/2025 13:06:00. 50 Economy ticket for £65 per person are available. Travel duration is 0h 57m
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LAN Perú0h 57m009:45La Florida, La Serena AirportLa Florida, La Serena Airport10:42Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 02/07/2025 09:45:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 02/07/2025 10:42:00. 50 Economy ticket for £76 per person are available. Travel duration is 0h 57m
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LAN Perú0h 57m021:02La Florida, La Serena AirportLa Florida, La Serena Airport21:59Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 02/07/2025 21:02:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 02/07/2025 21:59:00. 50 Economy ticket for £113 per person are available. Travel duration is 0h 57m
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Sky Airline1h 1m021:31La Florida, La Serena AirportLa Florida, La Serena Airport22:32Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 02/07/2025 21:31:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 02/07/2025 22:32:00. 50 Economy ticket for £72 per person are available. Travel duration is 1h 1m
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Cikbus Elité6h 0m016:30La SerenaBus Stop22:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 02/07/2025 16:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 02/07/2025 22:30:00. 50 Business ticket for £7 per person are available. Travel duration is 6h 0m
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FlixBus6h 5m006:00La SerenaBus Station12:05Santiago, RMTerminal San Borja0EconomyA Bus from FlixBus goes from Bus Station, La Serena (Chile) at 02/07/2025 06:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 02/07/2025 12:05:00. 50 Economy ticket for £9 per person are available. Travel duration is 6h 5m
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Cormar Bus6h 30m010:10La SerenaBus Station16:40Santiago, RMTerminal San Borja0First ClassA Bus from Cormar Bus goes from Bus Station, La Serena (Chile) at 02/07/2025 10:10:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 02/07/2025 16:40:00. 50 First Class ticket for £11 per person are available. Travel duration is 6h 30m
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Pluss Chile6h 40m000:05La SerenaBus Station06:45Santiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 02/07/2025 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 02/07/2025 06:45:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 40m
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Pullman San Andres7h 15m011:00La SerenaBus Station18:15Santiago, RMTerminal San Borja0First ClassA Bus from Pullman San Andres goes from Bus Station, La Serena (Chile) at 02/07/2025 11:00:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 02/07/2025 18:15:00. 50 First Class ticket for £12 per person are available. Travel duration is 7h 15m
Fastest Flights Wednesday
Fastest Buses Wednesday
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LAN Perú0h 57m012:00La Florida, La Serena AirportLa Florida, La Serena Airport12:57Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 03/07/2025 12:00:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 03/07/2025 12:57:00. 50 Economy ticket for £51 per person are available. Travel duration is 0h 57m
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LAN Perú0h 57m009:40La Florida, La Serena AirportLa Florida, La Serena Airport10:37Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 03/07/2025 09:40:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 03/07/2025 10:37:00. 50 Economy ticket for £65 per person are available. Travel duration is 0h 57m
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JetSmart0h 58m009:44La Florida, La Serena AirportLa Florida, La Serena Airport10:42Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 03/07/2025 09:44:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 03/07/2025 10:42:00. 50 Economy ticket for £39 per person are available. Travel duration is 0h 58m
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Sky Airline1h 1m011:05La Florida, La Serena AirportLa Florida, La Serena Airport12:06Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 03/07/2025 11:05:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 03/07/2025 12:06:00. 50 Economy ticket for £41 per person are available. Travel duration is 1h 1m
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Sky Airline1h 1m012:05La Florida, La Serena AirportLa Florida, La Serena Airport13:06Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 03/07/2025 12:05:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 03/07/2025 13:06:00. 50 Economy ticket for £41 per person are available. Travel duration is 1h 1m
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Nueva Andimar Vip6h 10m000:50La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 03/07/2025 00:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 03/07/2025 07:00:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Buses Romani6h 15m000:45La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 03/07/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 03/07/2025 07:00:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 15m
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Pluss Chile6h 40m000:05La SerenaBus Station06:45Santiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 03/07/2025 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 03/07/2025 06:45:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 40m
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Buses Paravias6h 40m023:30La SerenaBus Stop06:10Santiago, RMTerminal San Borja0BusinessA Bus from Buses Paravias goes from Bus Stop, La Serena (Chile) at 03/07/2025 23:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/07/2025 06:10:00. 50 Business ticket for £10 per person are available. Travel duration is 6h 40m
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Cikbus Elité7h 0m009:30La SerenaBus Stop16:30Santiago, RMTerminal San Borja0BusinessA Bus from Cikbus Elité goes from Bus Stop, La Serena (Chile) at 03/07/2025 09:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 03/07/2025 16:30:00. 50 Business ticket for £7 per person are available. Travel duration is 7h 0m
Fastest Flights Thursday
Fastest Buses Thursday
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LAN Airlines0h 57m022:11La Florida, La Serena AirportLa Florida, La Serena Airport23:08Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Airlines goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/07/2025 22:11:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/07/2025 23:08:00. 50 Economy ticket for £42 per person are available. Travel duration is 0h 57m
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LAN Perú0h 57m020:52La Florida, La Serena AirportLa Florida, La Serena Airport21:49Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/07/2025 20:52:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/07/2025 21:49:00. 50 Economy ticket for £43 per person are available. Travel duration is 0h 57m
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JetSmart0h 58m011:15La Florida, La Serena AirportLa Florida, La Serena Airport12:13Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/07/2025 11:15:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/07/2025 12:13:00. 50 Economy ticket for £42 per person are available. Travel duration is 0h 58m
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Sky Airline1h 1m011:58La Florida, La Serena AirportLa Florida, La Serena Airport12:59Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/07/2025 11:58:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/07/2025 12:59:00. 50 Economy ticket for £42 per person are available. Travel duration is 1h 1m
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Sky Airline1h 1m018:52La Florida, La Serena AirportLa Florida, La Serena Airport19:53Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 04/07/2025 18:52:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 04/07/2025 19:53:00. 50 Economy ticket for £47 per person are available. Travel duration is 1h 1m
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Nueva Andimar Vip6h 10m000:50La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 04/07/2025 00:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 04/07/2025 07:00:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Buses Romani6h 15m000:45La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 04/07/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 04/07/2025 07:00:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 15m
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Pluss Chile6h 40m000:05La SerenaBus Station06:45Santiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 04/07/2025 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 04/07/2025 06:45:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 40m
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Cormar Bus6h 50m015:30La SerenaBus Station22:20Santiago, RMTerminal San Borja0First ClassA Bus from Cormar Bus goes from Bus Station, La Serena (Chile) at 04/07/2025 15:30:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 04/07/2025 22:20:00. 50 First Class ticket for £9 per person are available. Travel duration is 6h 50m
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Cikbus Elité7h 20m001:10La SerenaBus Station08:30Santiago, RMSur Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Bus Station, La Serena (Chile) at 04/07/2025 01:10:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 04/07/2025 08:30:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 7h 20m
Fastest Flights Friday
Fastest Buses Friday
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LAN Perú0h 57m009:50La Florida, La Serena AirportLa Florida, La Serena Airport10:47Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/07/2025 09:50:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/07/2025 10:47:00. 50 Economy ticket for £43 per person are available. Travel duration is 0h 57m
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LAN Perú0h 57m011:34La Florida, La Serena AirportLa Florida, La Serena Airport12:31Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from LAN Perú goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/07/2025 11:34:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/07/2025 12:31:00. 50 Economy ticket for £49 per person are available. Travel duration is 0h 57m
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JetSmart0h 58m011:39La Florida, La Serena AirportLa Florida, La Serena Airport12:37Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from JetSmart goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/07/2025 11:39:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/07/2025 12:37:00. 50 Economy ticket for £57 per person are available. Travel duration is 0h 58m
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Sky Airline1h 1m017:34La Florida, La Serena AirportLa Florida, La Serena Airport18:35Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Sky Airline goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/07/2025 17:34:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/07/2025 18:35:00. 50 Economy ticket for £33 per person are available. Travel duration is 1h 1m
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Air China Cargo1h 1m017:34La Florida, La Serena AirportLa Florida, La Serena Airport18:35Santiago de Chile AirportSantiago de Chile Airport0EconomyA Flight from Air China Cargo goes from La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) at 05/07/2025 17:34:00 to Santiago de Chile Airport, Santiago de Chile Airport (Chile) arriving at 05/07/2025 18:35:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 1m
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Nueva Andimar Vip6h 10m000:50La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Nueva Andimar Vip goes from Bus Station, La Serena (Chile) at 05/07/2025 00:50:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/07/2025 07:00:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 10m
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Buses Romani6h 15m000:45La SerenaBus Station07:00Santiago, RMSur Bus Station0Premium EconomyA Bus from Buses Romani goes from Bus Station, La Serena (Chile) at 05/07/2025 00:45:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/07/2025 07:00:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 15m
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Pluss Chile6h 30m000:05La SerenaBus Station06:35Santiago, RMSur Bus Station0Premium EconomyA Bus from Pluss Chile goes from Bus Station, La Serena (Chile) at 05/07/2025 00:05:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/07/2025 06:35:00. 50 Premium Economy ticket for £6 per person are available. Travel duration is 6h 30m
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Turbus6h 50m003:15La SerenaBus Station10:05Santiago, RMTerminal San Borja0Premium EconomyA Bus from Turbus goes from Bus Station, La Serena (Chile) at 05/07/2025 03:15:00 to Terminal San Borja, Santiago, RM (Chile) arriving at 05/07/2025 10:05:00. 50 Premium Economy ticket for £9 per person are available. Travel duration is 6h 50m
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Cikbus Elité7h 20m001:10La SerenaBus Station08:30Santiago, RMSur Bus Station0Premium EconomyA Bus from Cikbus Elité goes from Bus Station, La Serena (Chile) at 05/07/2025 01:10:00 to Sur Bus Station, Santiago, RM (Chile) arriving at 05/07/2025 08:30:00. 50 Premium Economy ticket for £10 per person are available. Travel duration is 7h 20m
Fastest Flights Saturday
Fastest Buses Saturday
Here you will find all operators and timetables for a
Bus from La Serena to Santiago, RM
What are the most popular stations in La Serena and Santiago, RM?
In La Serena, you will usually depart from Bus Stop, Bus Station or Corsario, while in Santiago, RM you will be arriving at Terminal San Borja, Los Libertadores Bus Stop or Terminal Pajaritos, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Santiago, RM from La Serena? With 9 connections between 13 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between La Serena and Santiago, RM, you can pay as low as £5 with a Bus from Pluss Chile.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from LAN Perú: you will get to Santiago, RM in just 0h 56m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting La Serena and Santiago, RM are LAN Perú, Sky Airline and JetSmart, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in La Serena and Santiago, RM is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from La Florida, La Serena Airport or to Lo Prado, and look at flights from La Florida, La Serena Airport, and landing at Santiago de Chile Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from La Serena to Santiago, RM?
The most popular companies between La Serena and Santiago, RM, are LAN Perú, Sky Airline and JetSmart. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Pluss Chile, Cikbus Elité, Buses Romani and 8 more.
Airlines: LAN Perú, Sky Airline, JetSmart and 2 more.
All you need to know when you travel from La Serena to Santiago, RM
Check all information on comfort and services on all modes of transports from La Serena to Santiago, RM. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from La Serena to Santiago, RM
How can I reach Santiago, RM from La Serena?
Every day, there are on average 9 connections between Bus and Flight, with which you can get to Santiago, RM from La Serena.
How far is Santiago, RM from La Serena?
The distance between La Serena and Santiago, RM is 397.3 km.
What is the most ecofriendly mode of transport between La Serena and Santiago, RM?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 11 kgs of CO2, a train 14 kgs, a car 68 kgs, and a flight 98 kgs.
What is the cheapest mode of transport from La Serena to Santiago, RM?
You can get to Santiago, RM with just £5 by taking a Bus from Pluss Chile.
What is the fastest way to get from La Serena to Santiago, RM?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Santiago, RM in just 0h 56m with a Flight from LAN Perú.
More routes to La Serena and to Santiago, RM
Looking for more options? Here you can see the most popular routes to La Serena and to Santiago, RM. Simply click on a connection, and you’ll find all the details about the route!
- Trips to La Serena
- Antofagasta to La Serena
- Arica, AP to La Serena
- Calama to La Serena
- Concepción to La Serena
- Iquique to La Serena
- Mendoza to La Serena
- Puerto Montt to La Serena
- San Juan, SJ to La Serena
- Santiago, RM to La Serena
- Temuco to La Serena
- Trips to Santiago, RM
- Antofagasta to Santiago, RM
- Arica, AP to Santiago, RM
- Bariloche to Santiago, RM
- Buenos Aires to Santiago, RM
- Castro to Santiago, RM
- Concepción to Santiago, RM
- Copiapó to Santiago, RM
- Coquimbo to Santiago, RM
- Coronel to Santiago, RM
- Freire to Santiago, RM
- Iquique to Santiago, RM
- Los Ángeles, BI to Santiago, RM
- Mendoza to Santiago, RM
- Osorno, LL to Santiago, RM
- Porto Alegre, RS to Santiago, RM
- Puerto Montt to Santiago, RM
- Rio de Janeiro to Santiago, RM
- Santiago de Chile Airport to Santiago, RM
- Temuco to Santiago, RM
- Valdivia to Santiago, RM
- Viña del Mar to Santiago, RM