Which bus from Indianapolis to St. Louis, MO is the best?
Check the bus schedule for Indianapolis to St. Louis, MO. Here is a selection of the cheapest coach trips for the next days from bus operators like Greyhound US. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 3h 55m | 03:30 | Indianapolis | Central Coach Station | 06:25 | St. Louis, MO | Gateway Station | Economy | £26 |
A Bus from Greyhound US goes from Central Coach Station, Indianapolis (USA) at 06/12/2025 03:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 06/12/2025 06:25:00. 50 Economy ticket for £26 per person are available. Travel duration is 3h 55m
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| Greyhound US | 4h 55m | 11:25 | Indianapolis | Central Coach Station | 15:20 | St. Louis, MO | Gateway Station | Economy | £26 |
A Bus from Greyhound US goes from Central Coach Station, Indianapolis (USA) at 06/12/2025 11:25:00 to Gateway Station, St. Louis, MO (USA) arriving at 06/12/2025 15:20:00. 50 Economy ticket for £26 per person are available. Travel duration is 4h 55m
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| Greyhound US | 4h 20m | 20:05 | Indianapolis | Central Coach Station | 23:25 | St. Louis, MO | Gateway Station | Economy | £26 |
A Bus from Greyhound US goes from Central Coach Station, Indianapolis (USA) at 06/12/2025 20:05:00 to Gateway Station, St. Louis, MO (USA) arriving at 06/12/2025 23:25:00. 50 Economy ticket for £26 per person are available. Travel duration is 4h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 3h 55m | 03:30 | Indianapolis | Central Coach Station | 06:25 | St. Louis, MO | Gateway Station | Economy | £26 |
A Bus from Greyhound US goes from Central Coach Station, Indianapolis (USA) at 08/12/2025 03:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 08/12/2025 06:25:00. 50 Economy ticket for £26 per person are available. Travel duration is 3h 55m
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| Greyhound US | 4h 55m | 11:25 | Indianapolis | Central Coach Station | 15:20 | St. Louis, MO | Gateway Station | Economy | £26 |
A Bus from Greyhound US goes from Central Coach Station, Indianapolis (USA) at 08/12/2025 11:25:00 to Gateway Station, St. Louis, MO (USA) arriving at 08/12/2025 15:20:00. 50 Economy ticket for £26 per person are available. Travel duration is 4h 55m
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| Greyhound US | 4h 20m | 20:05 | Indianapolis | Central Coach Station | 23:25 | St. Louis, MO | Gateway Station | Economy | £26 |
A Bus from Greyhound US goes from Central Coach Station, Indianapolis (USA) at 08/12/2025 20:05:00 to Gateway Station, St. Louis, MO (USA) arriving at 08/12/2025 23:25:00. 50 Economy ticket for £26 per person are available. Travel duration is 4h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 3h 55m | 03:30 | Indianapolis | Central Coach Station | 06:25 | St. Louis, MO | Gateway Station | Economy | £30 |
A Bus from Greyhound US goes from Central Coach Station, Indianapolis (USA) at 10/12/2025 03:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 10/12/2025 06:25:00. 50 Economy ticket for £30 per person are available. Travel duration is 3h 55m
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| Greyhound US | 4h 55m | 11:25 | Indianapolis | Central Coach Station | 15:20 | St. Louis, MO | Gateway Station | Economy | £30 |
A Bus from Greyhound US goes from Central Coach Station, Indianapolis (USA) at 10/12/2025 11:25:00 to Gateway Station, St. Louis, MO (USA) arriving at 10/12/2025 15:20:00. 50 Economy ticket for £30 per person are available. Travel duration is 4h 55m
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| Greyhound US | 4h 20m | 20:05 | Indianapolis | Central Coach Station | 23:25 | St. Louis, MO | Gateway Station | Economy | £30 |
A Bus from Greyhound US goes from Central Coach Station, Indianapolis (USA) at 10/12/2025 20:05:00 to Gateway Station, St. Louis, MO (USA) arriving at 10/12/2025 23:25:00. 50 Economy ticket for £30 per person are available. Travel duration is 4h 20m
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Best Price Offer: The price for the cheapest coach from Indianapolis to St. Louis, MO is £25 on 04/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Indianapolis and St. Louis, MO?
Monday
is the busiest day, with more than 6 daily coaches from Indianapolis to St. Louis, MO. Wednesday has instead the fewest connections, with only 3 daily coaches between Indianapolis and St. Louis, MO.
The busiest time of the day is the Morning, with 5 coaches from Indianapolis to St. Louis, MO, while Morning sees the fewest connections between Indianapolis and St. Louis, MO, with 5 offers.
All facts for Indianapolis to St. Louis, MO bus at a glance
Compare all coach operators like Greyhound US that travel daily 5 times by bus from Indianapolis to St. Louis, MO in one click. Book your Indianapolis to St. Louis, MO bus ticket starting from £25!
| Cheapest Bus | £25 |
| Fastest Bus | 2h 55m |
| Earliest Coach | 03:30 |
| Latest Coach | 20:05 |
| Daily Bus Connections | 5 Ø |
| Distance | 371.4 km |
| Coach Companies | Greyhound US |
What are the cheapest coach tickets from Indianapolis to St. Louis, MO?
Every day, 5 buses from 1 coach companies leave Indianapolis for St. Louis, MO. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday
01/12
Tuesday
02/12
Wednesday
03/12
Thursday
04/12
Friday
05/12
Saturday
06/12
£26
Sunday
07/12
Monday
08/12
£26
Tuesday
09/12
Wednesday
10/12
£30
Thursday
11/12
Friday
12/12
Saturday
13/12
£32
Sunday
14/12
Monday
15/12
£26
Tuesday
16/12
Wednesday
17/12
Thursday
18/12
Friday
19/12
Saturday
20/12
Sunday
21/12
Monday
22/12
Tuesday
23/12
Wednesday
24/12
Thursday
25/12
Friday
26/12
Saturday
27/12
Sunday
28/12
The cheapest time to travel from Indianapolis to St. Louis, MO
With a price starting from £26, Saturday is the cheapest day for a coach from Indianapolis to St. Louis, MO. Wednesday instead is the most expensive day with prices starting from £30.
Morning
is the cheapest day time for bus tickets from Indianapolis to St. Louis, MO, with £26. Morning is the most expensive time of the day with prices starting from £26.
How to save money travelling from Indianapolis to St. Louis, MO
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.
Book the ticket from Indianapolis to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Indianapolis to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Indianapolis to St. Louis, MO are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Indianapolis and St. Louis, MO
Here is a map with all coach stations in Indianapolis and St. Louis, MO. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Indianapolis to St. Louis, MO
Check all information on comfort and services on the coaches from Indianapolis to St. Louis, MO. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.
FAQs for Indianapolis to St. Louis, MO bus
How much does a Indianapolis St. Louis, MO coach trip cost?
This depends on, among other things, the day and travel time. The cheapest ticket for the Indianapolis St. Louis, MO bus trip is available from £25 and takes 2h 55m. Compare offers and save money!
How much could I save by comparing buses from Indianapolis to St. Louis, MO?
This connection is offered by 1 companies with ticket prices ranging from £25 to £30. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to St. Louis, MO.
How many connections are available for the Indianapolis St. Louis, MO route on average every day?
Each day, the bus route from Indianapolis to St. Louis, MO is offered by roughly 5 busses. By using our search, you can compare bus schedules and find your ideal trip.
How long does a bus to St. Louis, MO from Indianapolis take?
The quickest coach from Indianapolis to St. Louis, MO is provided by Greyhound US and takes 2h 55m. Coach tickets for this connection cost £28. However, keep in mind that the connection can take longer due to traffic.
What time is the first bus from Indianapolis to St. Louis, MO?
The earliest bus to St. Louis, MO departs from Indianapolis at 03:30. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.
What time is the last coach from Indianapolis to St. Louis, MO?
The latest bus to St. Louis, MO departs from Indianapolis at 20:05. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.
Which bus companies serve the Indianapolis St. Louis, MO route?
Passengers looking to travel from Indianapolis to St. Louis, MO can travel with Greyhound US. Compare all available bus tickets with our search to book the trip that works best for you.
Is there a direct bus between Indianapolis and St. Louis, MO?
You can check all the direct connections between Indianapolis and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.
What can I take with me on the bus to St. Louis, MO from Indianapolis?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Indianapolis St. Louis, MO bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.
What equipment is available for the Indianapolis St. Louis, MO bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Indianapolis to St. Louis, MO on your planned travel date.
Available seat classes which are offered on the bus route Indianapolis to St. Louis, MO
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Indianapolis and to St. Louis, MO
Here’s an overview of the most popular bus routes to Indianapolis and to St. Louis, MO. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
