Which bus from Chicago to St. Louis, MO is the cheapest?

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Which bus from Chicago to St. Louis, MO is the best?

Check the bus schedule for Chicago to St. Louis, MO. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or Greyhound US. To see the full timetable for all coaches just use or search and compare.

today
£32
tomorrow
£27
Sunday
£33
Monday
£28
Tuesday
£30
Wednesday
£38
Thursday
£27

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 6h 10m 00:15 Chicago Downtown Coach Station 06:25 St. Louis, MO Gateway Station  Economy £32
FlixBus 6h 40m 16:30 Chicago Downtown Coach Station 23:10 St. Louis, MO Gateway Station  Economy £32
FlixBus 6h 0m 09:45 Chicago Downtown Coach Station 15:45 St. Louis, MO Gateway Station  Economy £34
Greyhound US 9h 10m 06:10 Chicago Downtown Coach Station 15:20 St. Louis, MO Gateway Station  Economy £37
Greyhound US 8h 45m 21:40 Chicago Downtown Coach Station 06:25 St. Louis, MO Gateway Station  Economy £43

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 6h 40m 16:30 Chicago Downtown Coach Station 23:10 St. Louis, MO Gateway Station  Economy £27
FlixBus 5h 35m 10:10 Chicago 95th Red Line Station 15:45 St. Louis, MO Gateway Station  Economy £27
FlixBus 5h 45m 00:40 Chicago 95th Red Line Station 06:25 St. Louis, MO Gateway Station  Economy £28
Greyhound US 7h 55m 22:30 Chicago 95th Red Line Station 06:25 St. Louis, MO Gateway Station  Economy £35
Greyhound US 9h 10m 06:10 Chicago Downtown Coach Station 15:20 St. Louis, MO Gateway Station  Economy £36

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 5h 45m 00:40 Chicago 95th Red Line Station 06:25 St. Louis, MO Gateway Station  Economy £33
FlixBus 6h 10m 00:15 Chicago Downtown Coach Station 06:25 St. Louis, MO Gateway Station  Economy £34
FlixBus 6h 0m 09:45 Chicago Downtown Coach Station 15:45 St. Louis, MO Gateway Station  Economy £34
Greyhound US 7h 55m 22:30 Chicago 95th Red Line Station 06:25 St. Louis, MO Gateway Station  Economy £42
Greyhound US 9h 10m 06:10 Chicago Downtown Coach Station 15:20 St. Louis, MO Gateway Station  Economy £47

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 6h 40m 16:30 Chicago Downtown Coach Station 23:10 St. Louis, MO Gateway Station  Economy £28
FlixBus 6h 10m 00:15 Chicago Downtown Coach Station 06:25 St. Louis, MO Gateway Station  Economy £29
FlixBus 5h 45m 00:40 Chicago 95th Red Line Station 06:25 St. Louis, MO Gateway Station  Economy £30
Greyhound US 7h 55m 22:30 Chicago 95th Red Line Station 06:25 St. Louis, MO Gateway Station  Economy £33
Greyhound US 9h 10m 06:10 Chicago Downtown Coach Station 15:20 St. Louis, MO Gateway Station  Economy £38

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 9h 15m 14:10 Chicago 95th Red Line Station 23:25 St. Louis, MO Gateway Station  Economy £30
Greyhound US 7h 55m 22:30 Chicago 95th Red Line Station 06:25 St. Louis, MO Gateway Station  Economy £30
FlixBus 9h 55m 05:25 Chicago 95th Red Line Station 15:20 St. Louis, MO Gateway Station  Economy £31
Greyhound US 9h 10m 06:10 Chicago Downtown Coach Station 15:20 St. Louis, MO Gateway Station  Economy £33

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 9h 10m 06:10 Chicago Downtown Coach Station 15:20 St. Louis, MO Gateway Station  Economy £38
Greyhound US 8h 40m 14:45 Chicago Downtown Coach Station 23:25 St. Louis, MO Gateway Station  Economy £38
Greyhound US 8h 45m 21:40 Chicago Downtown Coach Station 06:25 St. Louis, MO Gateway Station  Economy £38
Greyhound US 13h 25m 10:00 Chicago Union Station 23:25 St. Louis, MO Gateway Station  Economy £38
Greyhound US 8h 25m 22:00 Chicago Union Station 06:25 St. Louis, MO Gateway Station  Economy £38

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 5h 45m 00:40 Chicago 95th Red Line Station 06:25 St. Louis, MO Gateway Station  Economy £27
FlixBus 5h 35m 10:10 Chicago 95th Red Line Station 15:45 St. Louis, MO Gateway Station  Economy £28
FlixBus 6h 0m 17:10 Chicago 95th Red Line Station 23:10 St. Louis, MO Gateway Station  Economy £28
Greyhound US 7h 55m 22:30 Chicago 95th Red Line Station 06:25 St. Louis, MO Gateway Station  Economy £30
Greyhound US 9h 10m 06:10 Chicago Downtown Coach Station 15:20 St. Louis, MO Gateway Station  Economy £33

Best Price Offer: The price for the cheapest coach from Chicago to St. Louis, MO is £27 on 11/12/2025. Flexible travellers save on ticket prices.


What is the best day and time to travel by bus between Chicago and St. Louis, MO?

Here is the frequency of all coach connections from Chicago to St. Louis, MO. See on which day of the week you have more travel options and what time you have more bus trips to choose from.
Monday is the busiest day, with more than 22 daily coaches from Chicago to St. Louis, MO. Wednesday has instead the fewest connections, with only 5 daily coaches between Chicago and St. Louis, MO.
The busiest time of the day is the Evening, with 34 coaches from Chicago to St. Louis, MO, while Afternoon sees the fewest connections between Chicago and St. Louis, MO, with 22 offers.

All facts for Chicago to St. Louis, MO bus at a glance

Compare all coach operators like FlixBus and Greyhound US that travel daily 16 times by bus from Chicago to St. Louis, MO in one click. Book your Chicago to St. Louis, MO bus ticket starting from £27!

Cheapest Bus £27
Fastest Bus 5h 35m
Earliest Coach 00:15
Latest Coach 22:30
Daily Bus Connections 16 Ø
Distance 422.1 km
Coach Companies FlixBus and Greyhound US

What are the cheapest coach tickets from Chicago to St. Louis, MO?

Every day, 16 buses from 2 coach companies leave Chicago for St. Louis, MO. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 01/12
Tuesday 02/12
Wednesday 03/12
Thursday 04/12
Friday 05/12
£32
Saturday 06/12
£32
Sunday 07/12
£33
Monday 08/12
£28
Tuesday 09/12
£30
Wednesday 10/12
£38
Thursday 11/12
£27
Friday 12/12
Saturday 13/12
£34
Sunday 14/12
Monday 15/12
£28
Tuesday 16/12
£30
Wednesday 17/12
£30
Thursday 18/12
Friday 19/12
£34
Saturday 20/12
£31
Sunday 21/12
£34
Monday 22/12
Tuesday 23/12
£39
Wednesday 24/12
Thursday 25/12
£35
Friday 26/12
Saturday 27/12
£36
Sunday 28/12

The cheapest time to travel from Chicago to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to St. Louis, MO, for the next 30 days.
With a price starting from £27, Thursday is the cheapest day for a coach from Chicago to St. Louis, MO. Sunday instead is the most expensive day with prices starting from £33.
Night is the cheapest day time for bus tickets from Chicago to St. Louis, MO, with £27. Evening is the most expensive time of the day with prices starting from £30.

How to save money travelling from Chicago to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Chicago to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Chicago to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Chicago to St. Louis, MO are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

What are the most popular bus companies from Chicago to St. Louis, MO?

These are the most booked bus companies by our users on the Chicago to St. Louis, MO timetable.

FlixBus from Chicago to St. Louis, MO

FlixBus

Here you will find the key facts about the FlixBus bus route Chicago to St. Louis, MO:

Cheapest Price £27
Fastest Coach 5h 35m
Earliest Coach 00:15
Last Coach 17:10
Daily Connections 9 Ø
Found on 02/12/2025
In total 2 operators offer buses for this route. Find all bus timetables for them. Each coach company has a dedicated cancellation policy and possibilities for transport luggage on the bus. Check also special conditions to travel with kids or coach cards with rebates.

All bus stations and stops in Chicago and St. Louis, MO

Here is a map with all coach stations in Chicago and St. Louis, MO. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

All you need to know when you travel by bus from Chicago to St. Louis, MO

Check all information on comfort and services on the coaches from Chicago to St. Louis, MO. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Chicago to St. Louis, MO bus

How much does a Chicago St. Louis, MO coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Chicago St. Louis, MO bus trip is available from £27 and takes 5h 45m. Compare offers and save money!

How much could I save by comparing buses from Chicago to St. Louis, MO?

This connection is offered by 2 companies with ticket prices ranging from £27 to £49. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to St. Louis, MO.

How many connections are available for the Chicago St. Louis, MO route on average every day?

Each day, the bus route from Chicago to St. Louis, MO is offered by roughly 16 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to St. Louis, MO from Chicago take?

The quickest coach from Chicago to St. Louis, MO is provided by FlixBus and takes 5h 35m. Coach tickets for this connection cost £31. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Chicago to St. Louis, MO?

The earliest bus to St. Louis, MO departs from Chicago at 00:15. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Chicago to St. Louis, MO?

The latest bus to St. Louis, MO departs from Chicago at 22:30. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Chicago St. Louis, MO route?

Passengers looking to travel from Chicago to St. Louis, MO can travel with FlixBus and Greyhound US. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Chicago and St. Louis, MO?

You can check all the direct connections between Chicago and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the bus to St. Louis, MO from Chicago?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Chicago St. Louis, MO bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Chicago to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to St. Louis, MO

Here’s an overview of the most popular bus routes to Chicago and to St. Louis, MO. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
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Popular Airport Transfers to Chicago and to St. Louis, MO
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