Which bus from Charlotte, NC to St. Louis, MO is the best?
Check the bus schedule for Charlotte, NC to St. Louis, MO. Here is a selection of the cheapest coach trips for the next days from bus operators like FlixBus or Greyhound US. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 16h 30m | 17:40 | Charlotte, NC | W Trade St | 09:10 | St. Louis, MO | Gateway Station | Economy | £94 |
A Bus from FlixBus goes from W Trade St, Charlotte, NC (USA) at 05/12/2025 17:40:00 to Gateway Station, St. Louis, MO (USA) arriving at 06/12/2025 09:10:00. 50 Economy ticket for £94 per person are available. Travel duration is 16h 30m
|
||
| FlixBus | 31h 45m | 23:40 | Charlotte, NC | Freedom Drive 3301 | 06:25 | St. Louis, MO | Gateway Station | Economy | £94 |
A Bus from FlixBus goes from Freedom Drive 3301, Charlotte, NC (USA) at 05/12/2025 23:40:00 to Gateway Station, St. Louis, MO (USA) arriving at 07/12/2025 06:25:00. 50 Economy ticket for £94 per person are available. Travel duration is 31h 45m
|
||
| Greyhound US | 18h 25m | 22:30 | Charlotte, NC | W Trade St | 15:55 | St. Louis, MO | Gateway Station | Economy | £94 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 05/12/2025 22:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 06/12/2025 15:55:00. 50 Economy ticket for £94 per person are available. Travel duration is 18h 25m
|
||
| FlixBus | 23h 5m | 00:55 | Charlotte, NC | W Trade St | 23:00 | St. Louis, MO | Gateway Station | Economy | £95 |
A Bus from FlixBus goes from W Trade St, Charlotte, NC (USA) at 05/12/2025 00:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 05/12/2025 23:00:00. 50 Economy ticket for £95 per person are available. Travel duration is 23h 5m
|
||
| Greyhound US | 21h 35m | 02:50 | Charlotte, NC | W Trade St | 23:25 | St. Louis, MO | Gateway Station | Economy | £95 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 05/12/2025 02:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 05/12/2025 23:25:00. 50 Economy ticket for £95 per person are available. Travel duration is 21h 35m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 16h 30m | 17:40 | Charlotte, NC | W Trade St | 09:10 | St. Louis, MO | Gateway Station | Economy | £85 |
A Bus from FlixBus goes from W Trade St, Charlotte, NC (USA) at 06/12/2025 17:40:00 to Gateway Station, St. Louis, MO (USA) arriving at 07/12/2025 09:10:00. 50 Economy ticket for £85 per person are available. Travel duration is 16h 30m
|
||
| FlixBus | 27h 15m | 06:55 | Charlotte, NC | Freedom Drive 3301 | 09:10 | St. Louis, MO | Gateway Station | Economy | £85 |
A Bus from FlixBus goes from Freedom Drive 3301, Charlotte, NC (USA) at 06/12/2025 06:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 07/12/2025 09:10:00. 50 Economy ticket for £85 per person are available. Travel duration is 27h 15m
|
||
| Greyhound US | 22h 35m | 18:10 | Charlotte, NC | W Trade St | 15:45 | St. Louis, MO | Gateway Station | Economy | £85 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 06/12/2025 18:10:00 to Gateway Station, St. Louis, MO (USA) arriving at 07/12/2025 15:45:00. 50 Economy ticket for £85 per person are available. Travel duration is 22h 35m
|
||
| Greyhound US | 21h 35m | 02:50 | Charlotte, NC | W Trade St | 23:25 | St. Louis, MO | Gateway Station | Economy | £86 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 06/12/2025 02:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 06/12/2025 23:25:00. 50 Economy ticket for £86 per person are available. Travel duration is 21h 35m
|
||
| Greyhound US | 18h 25m | 22:30 | Charlotte, NC | W Trade St | 15:55 | St. Louis, MO | Gateway Station | Economy | £86 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 06/12/2025 22:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 07/12/2025 15:55:00. 50 Economy ticket for £86 per person are available. Travel duration is 18h 25m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 16h 30m | 17:40 | Charlotte, NC | W Trade St | 09:10 | St. Louis, MO | Gateway Station | Economy | £78 |
A Bus from FlixBus goes from W Trade St, Charlotte, NC (USA) at 07/12/2025 17:40:00 to Gateway Station, St. Louis, MO (USA) arriving at 08/12/2025 09:10:00. 50 Economy ticket for £78 per person are available. Travel duration is 16h 30m
|
||
| Greyhound US | 22h 35m | 18:10 | Charlotte, NC | W Trade St | 15:45 | St. Louis, MO | Gateway Station | Economy | £78 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 07/12/2025 18:10:00 to Gateway Station, St. Louis, MO (USA) arriving at 08/12/2025 15:45:00. 50 Economy ticket for £78 per person are available. Travel duration is 22h 35m
|
||
| FlixBus | 23h 5m | 00:55 | Charlotte, NC | W Trade St | 23:00 | St. Louis, MO | Gateway Station | Economy | £79 |
A Bus from FlixBus goes from W Trade St, Charlotte, NC (USA) at 07/12/2025 00:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 07/12/2025 23:00:00. 50 Economy ticket for £79 per person are available. Travel duration is 23h 5m
|
||
| FlixBus | 25h 15m | 08:55 | Charlotte, NC | Freedom Drive 3301 | 09:10 | St. Louis, MO | Gateway Station | Economy | £79 |
A Bus from FlixBus goes from Freedom Drive 3301, Charlotte, NC (USA) at 07/12/2025 08:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 08/12/2025 09:10:00. 50 Economy ticket for £79 per person are available. Travel duration is 25h 15m
|
||
| Greyhound US | 21h 35m | 02:50 | Charlotte, NC | W Trade St | 23:25 | St. Louis, MO | Gateway Station | Economy | £79 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 07/12/2025 02:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 07/12/2025 23:25:00. 50 Economy ticket for £79 per person are available. Travel duration is 21h 35m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 30h 20m | 18:05 | Charlotte, NC | Freedom Drive 3301 | 23:25 | St. Louis, MO | Gateway Station | Economy | £85 |
A Bus from FlixBus goes from Freedom Drive 3301, Charlotte, NC (USA) at 08/12/2025 18:05:00 to Gateway Station, St. Louis, MO (USA) arriving at 09/12/2025 23:25:00. 50 Economy ticket for £85 per person are available. Travel duration is 30h 20m
|
||
| FlixBus | 23h 5m | 00:55 | Charlotte, NC | W Trade St | 23:00 | St. Louis, MO | Gateway Station | Economy | £86 |
A Bus from FlixBus goes from W Trade St, Charlotte, NC (USA) at 08/12/2025 00:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 08/12/2025 23:00:00. 50 Economy ticket for £86 per person are available. Travel duration is 23h 5m
|
||
| FlixBus | 31h 45m | 23:40 | Charlotte, NC | Freedom Drive 3301 | 06:25 | St. Louis, MO | Gateway Station | Economy | £86 |
A Bus from FlixBus goes from Freedom Drive 3301, Charlotte, NC (USA) at 08/12/2025 23:40:00 to Gateway Station, St. Louis, MO (USA) arriving at 10/12/2025 06:25:00. 50 Economy ticket for £86 per person are available. Travel duration is 31h 45m
|
||
| Greyhound US | 21h 35m | 02:50 | Charlotte, NC | W Trade St | 23:25 | St. Louis, MO | Gateway Station | Economy | £86 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 08/12/2025 02:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 08/12/2025 23:25:00. 50 Economy ticket for £86 per person are available. Travel duration is 21h 35m
|
||
| Greyhound US | 25h 5m | 15:15 | Charlotte, NC | W Trade St | 15:20 | St. Louis, MO | Gateway Station | Economy | £86 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 08/12/2025 15:15:00 to Gateway Station, St. Louis, MO (USA) arriving at 09/12/2025 15:20:00. 50 Economy ticket for £86 per person are available. Travel duration is 25h 5m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 5m | 00:55 | Charlotte, NC | W Trade St | 23:00 | St. Louis, MO | Gateway Station | Economy | £79 |
A Bus from FlixBus goes from W Trade St, Charlotte, NC (USA) at 09/12/2025 00:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 09/12/2025 23:00:00. 50 Economy ticket for £79 per person are available. Travel duration is 23h 5m
|
||
| Greyhound US | 21h 35m | 02:50 | Charlotte, NC | W Trade St | 23:25 | St. Louis, MO | Gateway Station | Economy | £79 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 09/12/2025 02:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 09/12/2025 23:25:00. 50 Economy ticket for £79 per person are available. Travel duration is 21h 35m
|
||
| Greyhound US | 27h 30m | 12:50 | Charlotte, NC | W Trade St | 15:20 | St. Louis, MO | Gateway Station | Economy | £79 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 09/12/2025 12:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 10/12/2025 15:20:00. 50 Economy ticket for £79 per person are available. Travel duration is 27h 30m
|
||
| Greyhound US | 18h 25m | 22:30 | Charlotte, NC | W Trade St | 15:55 | St. Louis, MO | Gateway Station | Economy | £79 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 09/12/2025 22:30:00 to Gateway Station, St. Louis, MO (USA) arriving at 10/12/2025 15:55:00. 50 Economy ticket for £79 per person are available. Travel duration is 18h 25m
|
||
| FlixBus | 31h 45m | 23:40 | Charlotte, NC | Freedom Drive 3301 | 06:25 | St. Louis, MO | Gateway Station | Economy | £80 |
A Bus from FlixBus goes from Freedom Drive 3301, Charlotte, NC (USA) at 09/12/2025 23:40:00 to Gateway Station, St. Louis, MO (USA) arriving at 11/12/2025 06:25:00. 50 Economy ticket for £80 per person are available. Travel duration is 31h 45m
|
Best Price Offer: The price for the cheapest coach from Charlotte, NC to St. Louis, MO is £63 on 12/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Charlotte, NC and St. Louis, MO?
Monday
is the busiest day, with more than 16 daily coaches from Charlotte, NC to St. Louis, MO. Friday has instead the fewest connections, with only 8 daily coaches between Charlotte, NC and St. Louis, MO.
The busiest time of the day is the Evening, with 32 coaches from Charlotte, NC to St. Louis, MO, while Morning sees the fewest connections between Charlotte, NC and St. Louis, MO, with 7 offers.
All facts for Charlotte, NC to St. Louis, MO bus at a glance
Compare all coach operators like FlixBus and Greyhound US that travel daily 13 times by bus from Charlotte, NC to St. Louis, MO in one click. Book your Charlotte, NC to St. Louis, MO bus ticket starting from £63!
| Cheapest Bus | £63 |
| Fastest Bus | 15h 30m |
| Earliest Coach | 00:55 |
| Latest Coach | 23:40 |
| Daily Bus Connections | 13 Ø |
| Distance | 912.3 km |
| Coach Companies | FlixBus and Greyhound US |
What are the cheapest coach tickets from Charlotte, NC to St. Louis, MO?
Every day, 13 buses from 2 coach companies leave Charlotte, NC for St. Louis, MO. Check the table below to find the cheapest prices for coach tickets for this route, starting from 04/12/2025 and for the following days. Make sure get the cheapest bus ticket!
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday
01/12
Tuesday
02/12
Wednesday
03/12
Thursday
04/12
Friday
05/12
£94
Saturday
06/12
£85
Sunday
07/12
£78
Monday
08/12
£88
Tuesday
09/12
£79
Wednesday
10/12
Thursday
11/12
£78
Friday
12/12
£63
Saturday
13/12
Sunday
14/12
Monday
15/12
£89
Tuesday
16/12
£83
Wednesday
17/12
Thursday
18/12
Friday
19/12
Saturday
20/12
Sunday
21/12
Monday
22/12
Tuesday
23/12
Wednesday
24/12
Thursday
25/12
Friday
26/12
Saturday
27/12
Sunday
28/12
The cheapest time to travel from Charlotte, NC to St. Louis, MO
With a price starting from £63, Friday is the cheapest day for a coach from Charlotte, NC to St. Louis, MO. Saturday instead is the most expensive day with prices starting from £85.
Night
is the cheapest day time for bus tickets from Charlotte, NC to St. Louis, MO, with £63. Morning is the most expensive time of the day with prices starting from £79.
How to save money travelling from Charlotte, NC to St. Louis, MO
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.
Book the ticket from Charlotte, NC to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Charlotte, NC to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Charlotte, NC to St. Louis, MO are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Charlotte, NC and St. Louis, MO
Here is a map with all coach stations in Charlotte, NC and St. Louis, MO. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Charlotte, NC to St. Louis, MO
Check all information on comfort and services on the coaches from Charlotte, NC to St. Louis, MO. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.
FAQs for Charlotte, NC to St. Louis, MO bus
How much does a Charlotte, NC St. Louis, MO coach trip cost?
This depends on, among other things, the day and travel time. The cheapest ticket for the Charlotte, NC St. Louis, MO bus trip is available from £63 and takes 15h 30m. Compare offers and save money!
How much could I save by comparing buses from Charlotte, NC to St. Louis, MO?
This connection is offered by 2 companies with ticket prices ranging from £63 to £115. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to St. Louis, MO.
How many connections are available for the Charlotte, NC St. Louis, MO route on average every day?
Each day, the bus route from Charlotte, NC to St. Louis, MO is offered by roughly 13 busses. By using our search, you can compare bus schedules and find your ideal trip.
How long does a bus to St. Louis, MO from Charlotte, NC take?
The quickest coach from Charlotte, NC to St. Louis, MO is provided by FlixBus and takes 15h 30m. Coach tickets for this connection cost £94. However, keep in mind that the connection can take longer due to traffic.
What time is the first bus from Charlotte, NC to St. Louis, MO?
The earliest bus to St. Louis, MO departs from Charlotte, NC at 00:55. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.
What time is the last coach from Charlotte, NC to St. Louis, MO?
The latest bus to St. Louis, MO departs from Charlotte, NC at 23:40. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.
Which bus companies serve the Charlotte, NC St. Louis, MO route?
Passengers looking to travel from Charlotte, NC to St. Louis, MO can travel with FlixBus and Greyhound US. Compare all available bus tickets with our search to book the trip that works best for you.
Is there a direct bus between Charlotte, NC and St. Louis, MO?
You can check all the direct connections between Charlotte, NC and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.
What can I take with me on the bus to St. Louis, MO from Charlotte, NC?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Charlotte, NC St. Louis, MO bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.
What equipment is available for the Charlotte, NC St. Louis, MO bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Charlotte, NC to St. Louis, MO on your planned travel date.
Available seat classes which are offered on the bus route Charlotte, NC to St. Louis, MO
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Charlotte, NC and to St. Louis, MO
Here’s an overview of the most popular bus routes to Charlotte, NC and to St. Louis, MO. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
