Which bus from Charlotte, NC to St. Louis, MO is the best?
Check the bus schedule for Charlotte, NC to St. Louis, MO. Here is a selection of the cheapest coach trips for the next days from bus operators like Greyhound US or FlixBus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 21h 25m | 02:50 | Charlotte, NC | W Trade St | 23:15 | St. Louis, MO | Gateway Station | Economy | £69 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 04/06/2026 02:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 04/06/2026 23:15:00. 50 Economy ticket for £69 per person are available. Travel duration is 21h 25m
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| FlixBus | 27h 40m | 06:55 | Charlotte, NC | Freedom Drive 3301 | 09:35 | St. Louis, MO | Gateway Station | Economy | £69 |
A Bus from FlixBus goes from Freedom Drive 3301, Charlotte, NC (USA) at 04/06/2026 06:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 05/06/2026 09:35:00. 50 Economy ticket for £69 per person are available. Travel duration is 27h 40m
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| Greyhound US | 16h 15m | 18:20 | Charlotte, NC | W Trade St | 09:35 | St. Louis, MO | Gateway Station | Economy | £70 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 04/06/2026 18:20:00 to Gateway Station, St. Louis, MO (USA) arriving at 05/06/2026 09:35:00. 50 Economy ticket for £70 per person are available. Travel duration is 16h 15m
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| Greyhound US | 18h 45m | 22:10 | Charlotte, NC | W Trade St | 15:55 | St. Louis, MO | Gateway Station | Economy | £70 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 04/06/2026 22:10:00 to Gateway Station, St. Louis, MO (USA) arriving at 05/06/2026 15:55:00. 50 Economy ticket for £70 per person are available. Travel duration is 18h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 16h 15m | 18:20 | Charlotte, NC | W Trade St | 09:35 | St. Louis, MO | Gateway Station | Economy | £67 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 05/06/2026 18:20:00 to Gateway Station, St. Louis, MO (USA) arriving at 06/06/2026 09:35:00. 50 Economy ticket for £67 per person are available. Travel duration is 16h 15m
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| Greyhound US | 18h 45m | 22:10 | Charlotte, NC | W Trade St | 15:55 | St. Louis, MO | Gateway Station | Economy | £67 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 05/06/2026 22:10:00 to Gateway Station, St. Louis, MO (USA) arriving at 06/06/2026 15:55:00. 50 Economy ticket for £67 per person are available. Travel duration is 18h 45m
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| Greyhound US | 21h 25m | 02:50 | Charlotte, NC | W Trade St | 23:15 | St. Louis, MO | Gateway Station | Economy | £68 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 05/06/2026 02:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 05/06/2026 23:15:00. 50 Economy ticket for £68 per person are available. Travel duration is 21h 25m
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| FlixBus | 27h 40m | 06:55 | Charlotte, NC | Freedom Drive 3301 | 09:35 | St. Louis, MO | Gateway Station | Economy | £68 |
A Bus from FlixBus goes from Freedom Drive 3301, Charlotte, NC (USA) at 05/06/2026 06:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 06/06/2026 09:35:00. 50 Economy ticket for £68 per person are available. Travel duration is 27h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 21h 25m | 02:50 | Charlotte, NC | W Trade St | 23:15 | St. Louis, MO | Gateway Station | Economy | £70 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 06/06/2026 02:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 06/06/2026 23:15:00. 50 Economy ticket for £70 per person are available. Travel duration is 21h 25m
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| Greyhound US | 16h 15m | 18:20 | Charlotte, NC | W Trade St | 09:35 | St. Louis, MO | Gateway Station | Economy | £71 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 06/06/2026 18:20:00 to Gateway Station, St. Louis, MO (USA) arriving at 07/06/2026 09:35:00. 50 Economy ticket for £71 per person are available. Travel duration is 16h 15m
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| FlixBus | 27h 40m | 06:55 | Charlotte, NC | Freedom Drive 3301 | 09:35 | St. Louis, MO | Gateway Station | Economy | £71 |
A Bus from FlixBus goes from Freedom Drive 3301, Charlotte, NC (USA) at 06/06/2026 06:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 07/06/2026 09:35:00. 50 Economy ticket for £71 per person are available. Travel duration is 27h 40m
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| Greyhound US | 18h 45m | 22:10 | Charlotte, NC | W Trade St | 15:55 | St. Louis, MO | Gateway Station | Economy | £72 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 06/06/2026 22:10:00 to Gateway Station, St. Louis, MO (USA) arriving at 07/06/2026 15:55:00. 50 Economy ticket for £72 per person are available. Travel duration is 18h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 21h 25m | 02:50 | Charlotte, NC | W Trade St | 23:15 | St. Louis, MO | Gateway Station | Economy | £67 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 08/06/2026 02:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 08/06/2026 23:15:00. 50 Economy ticket for £67 per person are available. Travel duration is 21h 25m
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| Greyhound US | 16h 15m | 18:20 | Charlotte, NC | W Trade St | 09:35 | St. Louis, MO | Gateway Station | Economy | £67 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 08/06/2026 18:20:00 to Gateway Station, St. Louis, MO (USA) arriving at 09/06/2026 09:35:00. 50 Economy ticket for £67 per person are available. Travel duration is 16h 15m
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| Greyhound US | 18h 45m | 22:10 | Charlotte, NC | W Trade St | 15:55 | St. Louis, MO | Gateway Station | Economy | £67 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 08/06/2026 22:10:00 to Gateway Station, St. Louis, MO (USA) arriving at 09/06/2026 15:55:00. 50 Economy ticket for £67 per person are available. Travel duration is 18h 45m
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| FlixBus | 27h 40m | 06:55 | Charlotte, NC | Freedom Drive 3301 | 09:35 | St. Louis, MO | Gateway Station | Economy | £67 |
A Bus from FlixBus goes from Freedom Drive 3301, Charlotte, NC (USA) at 08/06/2026 06:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 09/06/2026 09:35:00. 50 Economy ticket for £67 per person are available. Travel duration is 27h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 16h 15m | 18:20 | Charlotte, NC | W Trade St | 09:35 | St. Louis, MO | Gateway Station | Economy | £71 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 09/06/2026 18:20:00 to Gateway Station, St. Louis, MO (USA) arriving at 10/06/2026 09:35:00. 50 Economy ticket for £71 per person are available. Travel duration is 16h 15m
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| FlixBus | 27h 40m | 06:55 | Charlotte, NC | Freedom Drive 3301 | 09:35 | St. Louis, MO | Gateway Station | Economy | £71 |
A Bus from FlixBus goes from Freedom Drive 3301, Charlotte, NC (USA) at 09/06/2026 06:55:00 to Gateway Station, St. Louis, MO (USA) arriving at 10/06/2026 09:35:00. 50 Economy ticket for £71 per person are available. Travel duration is 27h 40m
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| Greyhound US | 21h 25m | 02:50 | Charlotte, NC | W Trade St | 23:15 | St. Louis, MO | Gateway Station | Economy | £72 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 09/06/2026 02:50:00 to Gateway Station, St. Louis, MO (USA) arriving at 09/06/2026 23:15:00. 50 Economy ticket for £72 per person are available. Travel duration is 21h 25m
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| Greyhound US | 18h 45m | 22:10 | Charlotte, NC | W Trade St | 15:55 | St. Louis, MO | Gateway Station | Economy | £72 |
A Bus from Greyhound US goes from W Trade St, Charlotte, NC (USA) at 09/06/2026 22:10:00 to Gateway Station, St. Louis, MO (USA) arriving at 10/06/2026 15:55:00. 50 Economy ticket for £72 per person are available. Travel duration is 18h 45m
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Best Price Offer: The price for the cheapest coach from Charlotte, NC to St. Louis, MO is £60 on 26/06/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Charlotte, NC and St. Louis, MO?
All facts for Charlotte, NC to St. Louis, MO bus at a glance
Compare all coach operators like Greyhound US and FlixBus that travel daily 6 times by bus from Charlotte, NC to St. Louis, MO in one click. Book your Charlotte, NC to St. Louis, MO bus ticket starting from £60!
| Cheapest Bus | £60 |
| Fastest Bus | 15h 15m |
| Earliest Coach | 02:50 |
| Latest Coach | 22:10 |
| Daily Bus Connections | 6 Ø |
| Distance | 912.3 km |
| Coach Companies | Greyhound US and FlixBus |
What are the cheapest coach tickets from Charlotte, NC to St. Louis, MO?
Every day, 6 buses from 2 coach companies leave Charlotte, NC for St. Louis, MO. Check the table below to find the cheapest prices for coach tickets for this route, starting from 04/06/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Charlotte, NC to St. Louis, MO
How to save money travelling from Charlotte, NC to St. Louis, MO
Book the ticket from Charlotte, NC to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Charlotte, NC to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Charlotte, NC to St. Louis, MO are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
All bus stations and stops in Charlotte, NC and St. Louis, MO
Here is a map with all coach stations in Charlotte, NC and St. Louis, MO. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Charlotte, NC to St. Louis, MO
FAQs for Charlotte, NC to St. Louis, MO bus
How much does a Charlotte, NC St. Louis, MO coach trip cost?
How much could I save by comparing buses from Charlotte, NC to St. Louis, MO?
How many connections are available for the Charlotte, NC St. Louis, MO route on average every day?
How long does a bus to St. Louis, MO from Charlotte, NC take?
What time is the first bus from Charlotte, NC to St. Louis, MO?
What time is the last coach from Charlotte, NC to St. Louis, MO?
Which bus companies serve the Charlotte, NC St. Louis, MO route?
Is there a direct bus between Charlotte, NC and St. Louis, MO?
What can I take with me on the bus to St. Louis, MO from Charlotte, NC?
What equipment is available for the Charlotte, NC St. Louis, MO bus route?
How does CheckMyBus find the best coach deals from Charlotte, NC to St. Louis, MO?
How does CheckMyBus technology work for trips from Charlotte, NC to St. Louis, MO?
Available seat classes which are offered on the bus route Charlotte, NC to St. Louis, MO
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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