Which bus from Detroit to St. Louis, MO is the cheapest?

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Which bus from Detroit to St. Louis, MO is the best?

Check the bus schedule for Detroit to St. Louis, MO. Here is a selection of the cheapest coach trips for the next days from bus operators like Greyhound US. To see the full timetable for all coaches just use or search and compare.

today
£52
tomorrow
Thursday
£57
Friday
Saturday
£63
Sunday
£59
Monday
£52

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 16h 0m 08:20 Detroit Central Coach Station 23:20 St. Louis, MO Gateway Station  Economy £52
Greyhound US 15h 5m 16:20 Detroit Central Coach Station 06:25 St. Louis, MO Gateway Station  Economy £52
Greyhound US 12h 40m 20:15 Detroit Central Coach Station 07:55 St. Louis, MO Gateway Station  Economy £52
Greyhound US 16h 55m 23:15 Detroit Central Coach Station 15:10 St. Louis, MO Gateway Station  Economy £52

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 17h 30m 07:15 Detroit Central Coach Station 23:45 St. Louis, MO Gateway Station  Economy £57
Greyhound US 15h 5m 16:20 Detroit Central Coach Station 06:25 St. Louis, MO Gateway Station  Economy £57
Greyhound US 16h 55m 23:15 Detroit Central Coach Station 15:10 St. Louis, MO Gateway Station  Economy £57
Greyhound US 12h 40m 20:15 Detroit Central Coach Station 07:55 St. Louis, MO Gateway Station  Economy £58

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 16h 0m 08:20 Detroit Central Coach Station 23:20 St. Louis, MO Gateway Station  Economy £63
Greyhound US 15h 5m 16:20 Detroit Central Coach Station 06:25 St. Louis, MO Gateway Station  Economy £63
Greyhound US 12h 40m 20:15 Detroit Central Coach Station 07:55 St. Louis, MO Gateway Station  Economy £63
Greyhound US 17h 25m 23:15 Detroit Central Coach Station 15:40 St. Louis, MO Gateway Station  Economy £63
  • Did you know that if you travel from Detroit to St. Louis, MO via Chicago, you can save more than £9? You can find the corresponding connections below.
    • Greyhound US
      15h 5m
      0
      16:20
      Detroit
      Central Coach Station
      21:25
      Chicago
      Downtown Coach Station
      0
      Greyhound US
      Economy
      £25
      • Waiting Time 2h 50m
    • FlixBus
      6h 10m
      0
      00:15
      Chicago
      Downtown Coach Station
      06:25
      St. Louis, MO
      Gateway Station
      0
      FlixBus
      Economy
      £29
    Travel time is 3h 25m longer, but you will save £9

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 12h 40m 20:15 Detroit Central Coach Station 07:55 St. Louis, MO Gateway Station  Economy £59
Greyhound US 16h 0m 08:20 Detroit Central Coach Station 23:20 St. Louis, MO Gateway Station  Economy £60
Greyhound US 15h 5m 16:20 Detroit Central Coach Station 06:25 St. Louis, MO Gateway Station  Economy £60
Greyhound US 16h 55m 23:15 Detroit Central Coach Station 15:10 St. Louis, MO Gateway Station  Economy £60

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 16h 0m 08:20 Detroit Central Coach Station 23:20 St. Louis, MO Gateway Station  Economy £52
Greyhound US 15h 5m 16:20 Detroit Central Coach Station 06:25 St. Louis, MO Gateway Station  Economy £52
Greyhound US 12h 40m 20:15 Detroit Central Coach Station 07:55 St. Louis, MO Gateway Station  Economy £52
Greyhound US 16h 55m 23:15 Detroit Central Coach Station 15:10 St. Louis, MO Gateway Station  Economy £56

Best Price Offer: The price for the cheapest coach from Detroit to St. Louis, MO is £48 on 12/05/2026. Flexible travellers save on ticket prices.


What is the best day and time to travel by bus between Detroit and St. Louis, MO?

Here is the frequency of all coach connections from Detroit to St. Louis, MO. See on which day of the week you have more travel options and what time you have more bus trips to choose from.
Thursday is the busiest day, with more than 8 daily coaches from Detroit to St. Louis, MO. Tuesday has instead the fewest connections, with only 4 daily coaches between Detroit and St. Louis, MO.
The busiest time of the day is the Evening, with 17 coaches from Detroit to St. Louis, MO, while Morning sees the fewest connections between Detroit and St. Louis, MO, with 9 offers.

All facts for Detroit to St. Louis, MO bus at a glance

Compare all coach operators like Greyhound US that travel daily 7 times by bus from Detroit to St. Louis, MO in one click. Book your Detroit to St. Louis, MO bus ticket starting from £48!

Cheapest Bus £48
Fastest Bus 11h 40m
Earliest Coach 08:20
Latest Coach 23:15
Daily Bus Connections 7 Ø
Distance 731.6 km
Coach Companies Greyhound US

What are the cheapest coach tickets from Detroit to St. Louis, MO?

Every day, 7 buses from 1 coach companies leave Detroit for St. Louis, MO. Check the table below to find the cheapest prices for coach tickets for this route, starting from 21/04/2026 and for the following days. Make sure get the cheapest bus ticket!

Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
Monday 20/04
Tuesday 21/04
£52
Wednesday 22/04
Thursday 23/04
£57
Friday 24/04
Saturday 25/04
£63
Sunday 26/04
£59
Monday 27/04
£52
Tuesday 28/04
£52
Wednesday 29/04
£54
Thursday 30/04
£59
Friday 01/05
£51
Saturday 02/05
£54
Sunday 03/05
£56
Monday 04/05
£53
Tuesday 05/05
£52
Wednesday 06/05
Thursday 07/05
£55
Friday 08/05
Saturday 09/05
£58
Sunday 10/05
£51
Monday 11/05
£51
Tuesday 12/05
£48
Wednesday 13/05
£52
Thursday 14/05
£52
Friday 15/05
£55
Saturday 16/05
£56
Sunday 17/05

The cheapest time to travel from Detroit to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Detroit to St. Louis, MO, for the next 30 days.
With a price starting from £48, Tuesday is the cheapest day for a coach from Detroit to St. Louis, MO. Saturday instead is the most expensive day with prices starting from £54.
Afternoon is the cheapest day time for bus tickets from Detroit to St. Louis, MO, with £52. Morning is the most expensive time of the day with prices starting from £52.

How to save money travelling from Detroit to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying higher prices for your trip? Plan your bus trips smartly. Here are a few hacks to save money on your coach journey.

Book the ticket from Detroit to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Detroit to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Detroit to St. Louis, MO are also emptier.

Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.

All bus stations and stops in Detroit and St. Louis, MO

Here is a map with all coach stations in Detroit and St. Louis, MO. Compare which stop is closest to your destination to save time to find the fastest buses and connections.

All you need to know when you travel by bus from Detroit to St. Louis, MO

Check all information on comfort and services on the coaches from Detroit to St. Louis, MO. Which seat classes are available or what are the amenities of operators on your coach trip? Below you´ll find answers to your questions.

FAQs for Detroit to St. Louis, MO bus

How much does a Detroit St. Louis, MO coach trip cost?

This depends on, among other things, the day and travel time. The cheapest ticket for the Detroit St. Louis, MO bus trip is available from £48 and takes 14h 5m. Compare offers and save money!

How much could I save by comparing buses from Detroit to St. Louis, MO?

This connection is offered by 1 companies with ticket prices ranging from £48 to £75. Therefore, we suggest booking your ticket as soon as possible to ensure you’ll get the cheapest bus trip to St. Louis, MO.

How many connections are available for the Detroit St. Louis, MO route on average every day?

Each day, the bus route from Detroit to St. Louis, MO is offered by roughly 7 busses. By using our search, you can compare bus schedules and find your ideal trip.

How long does a bus to St. Louis, MO from Detroit take?

The quickest coach from Detroit to St. Louis, MO is provided by Greyhound US and takes 11h 40m. Coach tickets for this connection cost £52. However, keep in mind that the connection can take longer due to traffic.

What time is the first bus from Detroit to St. Louis, MO?

The earliest bus to St. Louis, MO departs from Detroit at 08:20. In this context, information about departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

What time is the last coach from Detroit to St. Louis, MO?

The latest bus to St. Louis, MO departs from Detroit at 23:15. Please note that departure times may differ on weekends and holidays. Simply use our search to find the exact times for your planned travel date.

Which bus companies serve the Detroit St. Louis, MO route?

Passengers looking to travel from Detroit to St. Louis, MO can travel with Greyhound US. Compare all available bus tickets with our search to book the trip that works best for you.

Is there a direct bus between Detroit and St. Louis, MO?

You can check all the direct connections between Detroit and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the bus to St. Louis, MO from Detroit?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the bus for the Detroit St. Louis, MO bus route free of charge. Simply use our search to find a coach that is best suited to your needs for your planned travel date.

What equipment is available for the Detroit St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make travelling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Detroit to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best coach deals from Detroit to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 7 daily trips between Detroit and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Detroit to St. Louis, MO?

Prices and availability for 7 trips between Detroit and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Detroit to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Detroit and to St. Louis, MO

Here’s an overview of the most popular bus routes to Detroit and to St. Louis, MO. Simply click on the connection of your choice, and you’ll find all the details about your bus route!
Bus Kalamazoo, MI to Detroit Bus Kalamazoo, MI to Detroit
Windsor, ON to Detroit coach Windsor, ON to Detroit coach
Bus from Washington, DC to Detroit Bus from Washington, DC to Detroit
Bus to Detroit from Chicago Bus to Detroit from Chicago
Bus from Wichita, KS to St. Louis, MO Bus from Wichita, KS to St. Louis, MO
Coach from Chicago to St. Louis, MO Coach from Chicago to St. Louis, MO
Bus from Charlotte, NC to St. Louis, MO Bus from Charlotte, NC to St. Louis, MO
Coach from Indianapolis to St. Louis, MO Coach from Indianapolis to St. Louis, MO
Popular Airport Transfers to Detroit and to St. Louis, MO
CheckMyBus › Coaches in USA › Coach to Detroit › Coach to St. Louis, MO

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