Which bus from Antofagasta to La Serena is the best?
Check the bus schedule for Antofagasta to La Serena. Here is a selection of the cheapest coach trips for the next days from bus operators like Pullman San Andres, Pluss Chile or Cikbus Elité. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pullman San Andres | 12h 10m | 13:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 01:10 | La Serena | Central Coach Station | Premium Economy | £25 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 06/08/2026 01:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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| FlixBus | 12h 10m | 21:50 | Antofagasta | Carlos Oviedo Cavada Bus Station | 10:00 | La Serena | Central Coach Station | Economy | £25 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/08/2026 21:50:00 to Central Coach Station, La Serena (Chile) arriving at 06/08/2026 10:00:00. 50 Economy ticket for £25 per person are available. Travel duration is 12h 10m
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| Cormar Bus | 12h 10m | 13:50 | Antofagasta | Camus Coach Station | 02:00 | La Serena | Central Coach Station | Premium Economy | £27 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 05/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 06/08/2026 02:00:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 12h 10m
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| Cikbus Elité | 11h 15m | 22:10 | Antofagasta | Carlos Oviedo Cavada Bus Station | 09:25 | La Serena | Central Coach Station | Premium Economy | £28 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/08/2026 22:10:00 to Central Coach Station, La Serena (Chile) arriving at 06/08/2026 09:25:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 11h 15m
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| Pullman Bus | 11h 35m | 10:30 | Antofagasta | Camus Coach Station | 22:05 | La Serena | El Sto, 1060 | First Class | £28 |
A Bus from Pullman Bus goes from Camus Coach Station, Antofagasta (Chile) at 05/08/2026 10:30:00 to El Sto, 1060, La Serena (Chile) arriving at 05/08/2026 22:05:00. 50 First Class ticket for £28 per person are available. Travel duration is 11h 35m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 12h 10m | 18:20 | Antofagasta | Carlos Oviedo Cavada Bus Station | 06:30 | La Serena | Central Coach Station | Economy | £24 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/08/2026 18:20:00 to Central Coach Station, La Serena (Chile) arriving at 07/08/2026 06:30:00. 50 Economy ticket for £24 per person are available. Travel duration is 12h 10m
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| Pullman San Andres | 12h 10m | 13:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 01:10 | La Serena | Central Coach Station | Premium Economy | £25 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 07/08/2026 01:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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| Nueva Andimar Vip | 12h 10m | 21:50 | Antofagasta | Carlos Oviedo Cavada Bus Station | 10:00 | La Serena | Central Coach Station | Economy | £25 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/08/2026 21:50:00 to Central Coach Station, La Serena (Chile) arriving at 07/08/2026 10:00:00. 50 Economy ticket for £25 per person are available. Travel duration is 12h 10m
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| Pullman Bus | 11h 50m | 21:00 | Antofagasta | Camus Coach Station | 08:50 | La Serena | El Sto, 1060 | First Class | £27 |
A Bus from Pullman Bus goes from Camus Coach Station, Antofagasta (Chile) at 06/08/2026 21:00:00 to El Sto, 1060, La Serena (Chile) arriving at 07/08/2026 08:50:00. 50 First Class ticket for £27 per person are available. Travel duration is 11h 50m
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| Cormar Bus | 12h 10m | 13:50 | Antofagasta | Camus Coach Station | 02:00 | La Serena | Central Coach Station | Premium Economy | £27 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 06/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 07/08/2026 02:00:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 12h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pullman Bus | 11h 50m | 01:00 | Antofagasta | Camus Coach Station | 12:50 | La Serena | El Sto, 1060 | First Class | £23 |
A Bus from Pullman Bus goes from Camus Coach Station, Antofagasta (Chile) at 07/08/2026 01:00:00 to El Sto, 1060, La Serena (Chile) arriving at 07/08/2026 12:50:00. 50 First Class ticket for £23 per person are available. Travel duration is 11h 50m
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| FlixBus | 12h 10m | 21:50 | Antofagasta | Carlos Oviedo Cavada Bus Station | 10:00 | La Serena | Central Coach Station | Economy | £23 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/08/2026 21:50:00 to Central Coach Station, La Serena (Chile) arriving at 08/08/2026 10:00:00. 50 Economy ticket for £23 per person are available. Travel duration is 12h 10m
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| Cormar Bus | 12h 10m | 13:50 | Antofagasta | Camus Coach Station | 02:00 | La Serena | Central Coach Station | Premium Economy | £24 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 07/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 08/08/2026 02:00:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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| Pullman San Andres | 12h 10m | 13:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 01:10 | La Serena | Central Coach Station | Premium Economy | £25 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 08/08/2026 01:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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| Nueva Andimar Vip | 12h 10m | 03:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 15:45 | La Serena | Central Coach Station | Economy | £27 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/08/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 07/08/2026 15:45:00. 50 Economy ticket for £27 per person are available. Travel duration is 12h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 12h 10m | 18:20 | Antofagasta | Carlos Oviedo Cavada Bus Station | 06:30 | La Serena | Central Coach Station | Economy | £21 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 08/08/2026 18:20:00 to Central Coach Station, La Serena (Chile) arriving at 09/08/2026 06:30:00. 50 Economy ticket for £21 per person are available. Travel duration is 12h 10m
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| Nueva Andimar Vip | 12h 10m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 13:45 | La Serena | Central Coach Station | Economy | £22 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 08/08/2026 01:35:00 to Central Coach Station, La Serena (Chile) arriving at 08/08/2026 13:45:00. 50 Economy ticket for £22 per person are available. Travel duration is 12h 10m
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| Cormar Bus | 12h 10m | 13:50 | Antofagasta | Camus Coach Station | 02:00 | La Serena | Central Coach Station | Premium Economy | £24 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 08/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 09/08/2026 02:00:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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| Pullman San Andres | 12h 10m | 13:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 01:10 | La Serena | Central Coach Station | Premium Economy | £25 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 08/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 09/08/2026 01:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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| Pullman Bus | 12h 50m | 02:30 | Antofagasta | Camus Coach Station | 15:20 | La Serena | El Sto, 1060 | First Class | £27 |
A Bus from Pullman Bus goes from Camus Coach Station, Antofagasta (Chile) at 08/08/2026 02:30:00 to El Sto, 1060, La Serena (Chile) arriving at 08/08/2026 15:20:00. 50 First Class ticket for £27 per person are available. Travel duration is 12h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cormar Bus | 12h 10m | 13:50 | Antofagasta | Camus Coach Station | 02:00 | La Serena | Central Coach Station | Premium Economy | £24 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 09/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 10/08/2026 02:00:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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| Pullman San Andres | 12h 10m | 13:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 01:10 | La Serena | Central Coach Station | Premium Economy | £25 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 09/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 10/08/2026 01:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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| Nueva Andimar Vip | 12h 10m | 03:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 15:45 | La Serena | Central Coach Station | Economy | £25 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 09/08/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 09/08/2026 15:45:00. 50 Economy ticket for £25 per person are available. Travel duration is 12h 10m
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| Pluss Chile | 10h 45m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 10:50 | La Serena | Central Coach Station | Premium Economy | £28 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 09/08/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 09/08/2026 10:50:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 10h 45m
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| Cikbus Elité | 13h 0m | 08:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 21:30 | La Serena | Central Coach Station | Premium Economy | £28 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 09/08/2026 08:30:00 to Central Coach Station, La Serena (Chile) arriving at 09/08/2026 21:30:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 13h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 12h 10m | 03:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 15:45 | La Serena | Central Coach Station | Economy | £20 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 10/08/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 10/08/2026 15:45:00. 50 Economy ticket for £20 per person are available. Travel duration is 12h 10m
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| Pullman San Andres | 12h 10m | 13:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 01:10 | La Serena | Central Coach Station | Premium Economy | £25 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 10/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 11/08/2026 01:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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| Cormar Bus | 12h 10m | 13:50 | Antofagasta | Camus Coach Station | 02:00 | La Serena | Central Coach Station | Premium Economy | £27 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 10/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 11/08/2026 02:00:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 12h 10m
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| Pluss Chile | 10h 45m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 10:50 | La Serena | Central Coach Station | Premium Economy | £28 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 10/08/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 10/08/2026 10:50:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 10h 45m
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| Cikbus Elité | 13h 0m | 08:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 21:30 | La Serena | Central Coach Station | Premium Economy | £28 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 10/08/2026 08:30:00 to Central Coach Station, La Serena (Chile) arriving at 10/08/2026 21:30:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 13h 0m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 12h 10m | 03:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 15:45 | La Serena | Central Coach Station | Economy | £19 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 11/08/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 11/08/2026 15:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 12h 10m
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| Nueva Andimar Vip | 12h 10m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 13:45 | La Serena | Central Coach Station | Economy | £20 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 11/08/2026 01:35:00 to Central Coach Station, La Serena (Chile) arriving at 11/08/2026 13:45:00. 50 Economy ticket for £20 per person are available. Travel duration is 12h 10m
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| Pullman San Andres | 12h 10m | 13:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 01:10 | La Serena | Central Coach Station | Premium Economy | £25 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 11/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 12/08/2026 01:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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| Cormar Bus | 12h 10m | 13:50 | Antofagasta | Camus Coach Station | 02:00 | La Serena | Central Coach Station | Premium Economy | £27 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 11/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 12/08/2026 02:00:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 12h 10m
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| Pluss Chile | 10h 45m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 10:50 | La Serena | Central Coach Station | Premium Economy | £28 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 11/08/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 11/08/2026 10:50:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 10h 45m
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Best Price Offer: The price for the cheapest coach from Antofagasta to La Serena is £18 on 19/08/2026. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Antofagasta and La Serena?
All facts for Antofagasta to La Serena bus at a glance
Compare all coach operators like Pullman San Andres, Pluss Chile and Cikbus Elité that travel daily 76 times by bus from Antofagasta to La Serena in one click. Book your Antofagasta to La Serena bus ticket starting from £18!
| Cheapest Bus | £18 |
| Fastest Bus | 10h 30m |
| Earliest Coach | 09:50 |
| Latest Coach | 23:59 |
| Daily Bus Connections | 76 Ø |
| Distance | 700.4 km |
| Coach Companies | Pullman San Andres, Pluss Chile, Cikbus Elité, Pullman Bus, Cormar Bus, FlixBus and Nueva Andimar Vip |
What are the cheapest coach tickets from Antofagasta to La Serena?
Every day, 76 buses from 7 coach companies leave Antofagasta for La Serena. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/08/2026 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Antofagasta to La Serena
How to save money travelling from Antofagasta to La Serena
Book the ticket from Antofagasta to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Antofagasta to La Serena, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Antofagasta to La Serena are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
Latest reviews for coach companies on the route Antofagasta - La Serena
All bus stations and stops in Antofagasta and La Serena
Here is a map with all coach stations in Antofagasta and La Serena. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
All you need to know when you travel by bus from Antofagasta to La Serena
FAQs for Antofagasta to La Serena bus
How much does a Antofagasta La Serena coach trip cost?
How much could I save by comparing buses from Antofagasta to La Serena?
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How long does a bus to La Serena from Antofagasta take?
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What time is the last coach from Antofagasta to La Serena?
Which bus companies serve the Antofagasta La Serena route?
Is there a direct bus between Antofagasta and La Serena?
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What equipment is available for the Antofagasta La Serena bus route?
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Available seat classes which are offered on the bus route Antofagasta to La Serena
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
Best of the best: you will find the most comfortable accommodation to work or relax during your travel.
More bus routes to Antofagasta and to La Serena
- Bus Routes to Antofagasta
- Coach from Alto Hospicio to Antofagasta
- Baquedano to Antofagasta bus
- Buses Bilbao to Antofagasta
- Bus from Calama to Antofagasta
- Bus to Antofagasta from Concepción
- Bus to Antofagasta from Coquimbo
- Coach Iquique to Antofagasta
- Coach to Antofagasta from La Calera
- Los Vilos to Antofagasta coach
- Bus to Antofagasta from Mejillones
- Oruro to Antofagasta coach
- Ovalle to Antofagasta bus
- Coach to Antofagasta from Santiago, RM
- Coach from Sierra Gorda to Antofagasta
- Coaches Valparaíso (CL) to Antofagasta
- Bus Routes to La Serena
- Bus from Alto Hospicio to La Serena
- Buses Arica, AP to La Serena
- Bus Chillán to La Serena
- Buses Concepción to La Serena
- Bus from Curicó to La Serena
- Buses Diego de Almagro to La Serena
- Bus to La Serena from Iquique
- Los Vilos to La Serena coach
- Bus to La Serena from Mendoza
- Ovalle to La Serena bus
- Coach to La Serena from Puerto Montt
- Bus to La Serena from San Juan, SJ
- Bus to La Serena from Sierra Gorda
- Coaches Valdivia to La Serena
- Bus Vallenar to La Serena
- Coach Viña del Mar to La Serena
