Which bus from Antofagasta to La Serena is the best?
Check the bus schedule for Antofagasta to La Serena. Here is a selection of the cheapest coach trips for the next days from bus operators like Pluss Chile, Pullman San Andres or Pullman Bus. To see the full timetable for all coaches just use or search and compare.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 12h 10m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 13:45 | La Serena | Central Coach Station | Economy | £18 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/12/2025 01:35:00 to Central Coach Station, La Serena (Chile) arriving at 05/12/2025 13:45:00. 50 Economy ticket for £18 per person are available. Travel duration is 12h 10m
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| Pullman San Andres | 12h 10m | 01:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 13:40 | La Serena | Central Coach Station | Premium Economy | £26 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/12/2025 01:30:00 to Central Coach Station, La Serena (Chile) arriving at 05/12/2025 13:40:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
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| Cormar Bus | 11h 20m | 20:20 | Antofagasta | Camus Coach Station | 07:40 | La Serena | Central Coach Station | First Class | £27 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 05/12/2025 20:20:00 to Central Coach Station, La Serena (Chile) arriving at 06/12/2025 07:40:00. 50 First Class ticket for £27 per person are available. Travel duration is 11h 20m
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| Pluss Chile | 10h 45m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 10:50 | La Serena | Central Coach Station | Premium Economy | £29 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/12/2025 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 05/12/2025 10:50:00. 50 Premium Economy ticket for £29 per person are available. Travel duration is 10h 45m
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| Pullman Bus | 11h 50m | 00:30 | Antofagasta | Camus Coach Station | 12:20 | La Serena | El Sto, 1060 | First Class | £29 |
A Bus from Pullman Bus goes from Camus Coach Station, Antofagasta (Chile) at 05/12/2025 00:30:00 to El Sto, 1060, La Serena (Chile) arriving at 05/12/2025 12:20:00. 50 First Class ticket for £29 per person are available. Travel duration is 11h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 12h 10m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 13:45 | La Serena | Central Coach Station | Economy | £18 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/12/2025 01:35:00 to Central Coach Station, La Serena (Chile) arriving at 06/12/2025 13:45:00. 50 Economy ticket for £18 per person are available. Travel duration is 12h 10m
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| Cormar Bus | 10h 30m | 21:45 | Antofagasta | Carlos Oviedo Cavada Bus Station | 08:15 | La Serena | Central Coach Station | First Class | £28 |
A Bus from Cormar Bus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/12/2025 21:45:00 to Central Coach Station, La Serena (Chile) arriving at 07/12/2025 08:15:00. 50 First Class ticket for £28 per person are available. Travel duration is 10h 30m
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| Pluss Chile | 10h 45m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 10:50 | La Serena | Central Coach Station | Premium Economy | £29 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/12/2025 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 06/12/2025 10:50:00. 50 Premium Economy ticket for £29 per person are available. Travel duration is 10h 45m
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| Pullman Bus | 11h 50m | 00:30 | Antofagasta | Camus Coach Station | 12:20 | La Serena | El Sto, 1060 | First Class | £29 |
A Bus from Pullman Bus goes from Camus Coach Station, Antofagasta (Chile) at 06/12/2025 00:30:00 to El Sto, 1060, La Serena (Chile) arriving at 06/12/2025 12:20:00. 50 First Class ticket for £29 per person are available. Travel duration is 11h 50m
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| Pullman San Andres | 12h 10m | 01:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 13:40 | La Serena | Central Coach Station | First Class | £29 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/12/2025 01:30:00 to Central Coach Station, La Serena (Chile) arriving at 06/12/2025 13:40:00. 50 First Class ticket for £29 per person are available. Travel duration is 12h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 12h 10m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 13:45 | La Serena | Central Coach Station | Economy | £18 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/12/2025 01:35:00 to Central Coach Station, La Serena (Chile) arriving at 07/12/2025 13:45:00. 50 Economy ticket for £18 per person are available. Travel duration is 12h 10m
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| Pluss Chile | 10h 45m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 10:50 | La Serena | Central Coach Station | Premium Economy | £21 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/12/2025 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 07/12/2025 10:50:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 10h 45m
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| Cikbus Elité | 11h 20m | 01:10 | Antofagasta | Carlos Oviedo Cavada Bus Station | 12:30 | La Serena | Central Coach Station | Premium Economy | £21 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/12/2025 01:10:00 to Central Coach Station, La Serena (Chile) arriving at 07/12/2025 12:30:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 11h 20m
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| Cormar Bus | 11h 41m | 23:59 | Antofagasta | Camus Coach Station | 11:40 | La Serena | Central Coach Station | Premium Economy | £24 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 07/12/2025 23:59:00 to Central Coach Station, La Serena (Chile) arriving at 08/12/2025 11:40:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 11h 41m
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| Pullman San Andres | 12h 10m | 11:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 23:10 | La Serena | Central Coach Station | Premium Economy | £26 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/12/2025 11:00:00 to Central Coach Station, La Serena (Chile) arriving at 07/12/2025 23:10:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 12h 10m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 13:45 | La Serena | Central Coach Station | Economy | £18 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 08/12/2025 01:35:00 to Central Coach Station, La Serena (Chile) arriving at 08/12/2025 13:45:00. 50 Economy ticket for £18 per person are available. Travel duration is 12h 10m
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| Cikbus Elité | 11h 15m | 03:10 | Antofagasta | Carlos Oviedo Cavada Bus Station | 14:25 | La Serena | Central Coach Station | Premium Economy | £21 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 08/12/2025 03:10:00 to Central Coach Station, La Serena (Chile) arriving at 08/12/2025 14:25:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 11h 15m
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| Pullman San Andres | 12h 10m | 11:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 23:10 | La Serena | Central Coach Station | Premium Economy | £26 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 08/12/2025 11:00:00 to Central Coach Station, La Serena (Chile) arriving at 08/12/2025 23:10:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
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| Pluss Chile | 10h 45m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 10:50 | La Serena | Central Coach Station | Premium Economy | £29 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 08/12/2025 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 08/12/2025 10:50:00. 50 Premium Economy ticket for £29 per person are available. Travel duration is 10h 45m
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| Pullman Bus | 11h 50m | 00:30 | Antofagasta | Camus Coach Station | 12:20 | La Serena | El Sto, 1060 | First Class | £29 |
A Bus from Pullman Bus goes from Camus Coach Station, Antofagasta (Chile) at 08/12/2025 00:30:00 to El Sto, 1060, La Serena (Chile) arriving at 08/12/2025 12:20:00. 50 First Class ticket for £29 per person are available. Travel duration is 11h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 12h 10m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 13:45 | La Serena | Central Coach Station | Economy | £18 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 09/12/2025 01:35:00 to Central Coach Station, La Serena (Chile) arriving at 09/12/2025 13:45:00. 50 Economy ticket for £18 per person are available. Travel duration is 12h 10m
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| Cikbus Elité | 11h 15m | 03:10 | Antofagasta | Carlos Oviedo Cavada Bus Station | 14:25 | La Serena | Central Coach Station | Premium Economy | £21 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 09/12/2025 03:10:00 to Central Coach Station, La Serena (Chile) arriving at 09/12/2025 14:25:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 11h 15m
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| Cormar Bus | 11h 41m | 23:59 | Antofagasta | Camus Coach Station | 11:40 | La Serena | Central Coach Station | Premium Economy | £24 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 09/12/2025 23:59:00 to Central Coach Station, La Serena (Chile) arriving at 10/12/2025 11:40:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 11h 41m
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| Pullman Bus | 11h 35m | 20:30 | Antofagasta | Camus Coach Station | 08:05 | La Serena | El Sto, 1060 | First Class | £24 |
A Bus from Pullman Bus goes from Camus Coach Station, Antofagasta (Chile) at 09/12/2025 20:30:00 to El Sto, 1060, La Serena (Chile) arriving at 10/12/2025 08:05:00. 50 First Class ticket for £24 per person are available. Travel duration is 11h 35m
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| Pullman San Andres | 12h 10m | 01:30 | Antofagasta | Carlos Oviedo Cavada Bus Station | 13:40 | La Serena | Central Coach Station | First Class | £29 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 09/12/2025 01:30:00 to Central Coach Station, La Serena (Chile) arriving at 09/12/2025 13:40:00. 50 First Class ticket for £29 per person are available. Travel duration is 12h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 12h 10m | 03:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 15:45 | La Serena | Central Coach Station | Economy | £18 |
A Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 10/12/2025 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 10/12/2025 15:45:00. 50 Economy ticket for £18 per person are available. Travel duration is 12h 10m
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| Nueva Andimar Vip | 12h 10m | 22:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 10:10 | La Serena | Central Coach Station | Economy | £20 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 10/12/2025 22:00:00 to Central Coach Station, La Serena (Chile) arriving at 11/12/2025 10:10:00. 50 Economy ticket for £20 per person are available. Travel duration is 12h 10m
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| Cikbus Elité | 11h 15m | 03:10 | Antofagasta | Carlos Oviedo Cavada Bus Station | 14:25 | La Serena | Central Coach Station | Premium Economy | £21 |
A Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 10/12/2025 03:10:00 to Central Coach Station, La Serena (Chile) arriving at 10/12/2025 14:25:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 11h 15m
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| Cormar Bus | 11h 24m | 12:25 | Antofagasta | Camus Coach Station | 23:49 | La Serena | Central Coach Station | First Class | £29 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 10/12/2025 12:25:00 to Central Coach Station, La Serena (Chile) arriving at 10/12/2025 23:49:00. 50 First Class ticket for £29 per person are available. Travel duration is 11h 24m
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| Pluss Chile | 10h 45m | 00:05 | Antofagasta | Carlos Oviedo Cavada Bus Station | 10:50 | La Serena | Central Coach Station | Premium Economy | £29 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 10/12/2025 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 10/12/2025 10:50:00. 50 Premium Economy ticket for £29 per person are available. Travel duration is 10h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nueva Andimar Vip | 12h 10m | 01:35 | Antofagasta | Carlos Oviedo Cavada Bus Station | 13:45 | La Serena | Central Coach Station | Economy | £18 |
A Bus from Nueva Andimar Vip goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 11/12/2025 01:35:00 to Central Coach Station, La Serena (Chile) arriving at 11/12/2025 13:45:00. 50 Economy ticket for £18 per person are available. Travel duration is 12h 10m
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| Cormar Bus | 11h 41m | 23:59 | Antofagasta | Camus Coach Station | 11:40 | La Serena | Central Coach Station | Premium Economy | £21 |
A Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 11/12/2025 23:59:00 to Central Coach Station, La Serena (Chile) arriving at 12/12/2025 11:40:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 11h 41m
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| Pluss Chile | 11h 35m | 02:15 | Antofagasta | Carlos Oviedo Cavada Bus Station | 13:50 | La Serena | Central Coach Station | Premium Economy | £21 |
A Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 11/12/2025 02:15:00 to Central Coach Station, La Serena (Chile) arriving at 11/12/2025 13:50:00. 50 Premium Economy ticket for £21 per person are available. Travel duration is 11h 35m
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| Pullman San Andres | 12h 10m | 11:00 | Antofagasta | Carlos Oviedo Cavada Bus Station | 23:10 | La Serena | Central Coach Station | Premium Economy | £26 |
A Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 11/12/2025 11:00:00 to Central Coach Station, La Serena (Chile) arriving at 11/12/2025 23:10:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
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| Pullman Bus | 11h 50m | 00:30 | Antofagasta | Camus Coach Station | 12:20 | La Serena | El Sto, 1060 | First Class | £29 |
A Bus from Pullman Bus goes from Camus Coach Station, Antofagasta (Chile) at 11/12/2025 00:30:00 to El Sto, 1060, La Serena (Chile) arriving at 11/12/2025 12:20:00. 50 First Class ticket for £29 per person are available. Travel duration is 11h 50m
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Best Price Offer: The price for the cheapest coach from Antofagasta to La Serena is £15 on 09/12/2025. Flexible travellers save on ticket prices.
What is the best day and time to travel by bus between Antofagasta and La Serena?
All facts for Antofagasta to La Serena bus at a glance
Compare all coach operators like Pluss Chile, Pullman San Andres and Pullman Bus that travel daily 77 times by bus from Antofagasta to La Serena in one click. Book your Antofagasta to La Serena bus ticket starting from £15!
| Cheapest Bus | £15 |
| Fastest Bus | 10h 30m |
| Earliest Coach | 00:05 |
| Latest Coach | 23:59 |
| Daily Bus Connections | 77 Ø |
| Distance | 700.4 km |
| Coach Companies | Pluss Chile, Pullman San Andres, Pullman Bus, Cikbus Elité, Cormar Bus, Nueva Andimar Vip and FlixBus |
What are the cheapest coach tickets from Antofagasta to La Serena?
Every day, 77 buses from 7 coach companies leave Antofagasta for La Serena. Check the table below to find the cheapest prices for coach tickets for this route, starting from 05/12/2025 and for the following days. Make sure get the cheapest bus ticket!
The cheapest time to travel from Antofagasta to La Serena
How to save money travelling from Antofagasta to La Serena
Book the ticket from Antofagasta to La Serena in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the coach from Antofagasta to La Serena, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later coaches from Antofagasta to La Serena are also emptier.Check for bus deals and promotions for all bus companies in this route. On CheckMyBus we show special offers directly in the coach trip on our search. Sign-up and check or deals sections and get notifications on our latest travel hacks.
Latest reviews for coach companies on the route Antofagasta - La Serena
All bus stations and stops in Antofagasta and La Serena
Here is a map with all coach stations in Antofagasta and La Serena. Compare which stop is closest to your destination to save time to find the fastest buses and connections.
Compare the bus with other modes of transport
All you need to know when you travel by bus from Antofagasta to La Serena
FAQs for Antofagasta to La Serena bus
How much does a Antofagasta La Serena coach trip cost?
How much could I save by comparing buses from Antofagasta to La Serena?
How many connections are available for the Antofagasta La Serena route on average every day?
How long does a bus to La Serena from Antofagasta take?
What time is the first bus from Antofagasta to La Serena?
What time is the last coach from Antofagasta to La Serena?
Which bus companies serve the Antofagasta La Serena route?
Is there a direct bus between Antofagasta and La Serena?
What can I take with me on the bus to La Serena from Antofagasta?
What equipment is available for the Antofagasta La Serena bus route?
Available seat classes which are offered on the bus route Antofagasta to La Serena
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
Best of the best: you will find the most comfortable accommodation to work or relax during your travel.
More bus routes to Antofagasta and to La Serena
- Bus Routes to Antofagasta
- Coach from Alto Hospicio to Antofagasta
- Baquedano to Antofagasta bus
- Bus from Calama to Antofagasta
- Bus Cochabamba to Antofagasta
- Coach Copiapó to Antofagasta
- Coach to Antofagasta from La Calera
- Los Vilos to Antofagasta coach
- Bus to Antofagasta from Mejillones
- Oruro to Antofagasta coach
- Buses Pozo Almonte to Antofagasta
- Buses Salta to Antofagasta
- Coach from San Pedro de Atacama to Antofagasta
- Coach to Antofagasta from Santiago, RM
- Coach from Sierra Gorda to Antofagasta
- Coach to Antofagasta from Tocopilla
- Coaches Vallenar to Antofagasta
- Coaches Valparaíso (CL) to Antofagasta
- Coaches Viña del Mar to Antofagasta
- Bus Routes to La Serena
- Bus from Alto Hospicio to La Serena
- Coaches Calama to La Serena
- Buses Concepción to La Serena
- Buses Diego de Almagro to La Serena
- Bus from La Calera to La Serena
- Los Vilos to La Serena coach
- Bus to La Serena from Mendoza
- Ovalle to La Serena bus
- Bus Pozo Almonte to La Serena
- Bus from Quilpué to La Serena
- Bus Rancagua to La Serena
- Bus to La Serena from San Juan, SJ
- Coaches Santiago, RM to La Serena
- Bus to La Serena from Sierra Gorda
- Bus Talca, ML to La Serena
- Buses Temuco to La Serena
- Bus to La Serena from Tocopilla
- Bus Vallenar to La Serena
- Coach Viña del Mar to La Serena

