What is the best way to travel from Antofagasta to La Serena?
Looking for a trip? Check and compare all the available Buses and Flights to La Serena from Antofagasta. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 8 available companies to find your perfect trip!
What is the cheapest way to reach La Serena from Antofagasta?
You can reach La Serena with just £13 by taking a Flight from Sky Airline, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 21/08/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 21/08/2026 10:50:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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Pullman San Andres12h 10m013:00AntofagastaCarlos Oviedo Cavada Bus Station01:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 21/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 22/08/2026 01:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Cormar Bus12h 10m013:50AntofagastaCamus Coach Station02:00La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 21/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 22/08/2026 02:00:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Andimar12h 10m021:50AntofagastaCarlos Oviedo Cavada Bus Station10:00La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 21/08/2026 21:50:00 to Central Coach Station, La Serena (Chile) arriving at 22/08/2026 10:00:00. 50 Economy ticket for £25 per person are available. Travel duration is 12h 10m
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Cikbus Elité11h 25m013:35AntofagastaCarlos Oviedo Cavada Bus Station01:00La SerenaCentral Coach Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 21/08/2026 13:35:00 to Central Coach Station, La Serena (Chile) arriving at 22/08/2026 01:00:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 11h 25m
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JetSmart20h 50m021:06Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:56La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 21/08/2026 21:06:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 22/08/2026 17:56:00. 50 Economy ticket for £70 per person are available. Travel duration is 20h 50m
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LATAM Brasil22h 7m019:49Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:56La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 21/08/2026 19:49:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 22/08/2026 17:56:00. 50 Economy ticket for £88 per person are available. Travel duration is 22h 7m
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LAN Airlines22h 7m019:49Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:56La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 21/08/2026 19:49:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 22/08/2026 17:56:00. 50 Economy ticket for £89 per person are available. Travel duration is 22h 7m
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Sky Airline1h 26m015:03Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport16:29La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 21/08/2026 15:03:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 21/08/2026 16:29:00. 50 Economy ticket for £126 per person are available. Travel duration is 1h 26m
Cheapest Buses Friday
Cheapest Flights Friday
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Andimar12h 10m003:35AntofagastaCarlos Oviedo Cavada Bus Station15:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 22/08/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 22/08/2026 15:45:00. 50 Economy ticket for £23 per person are available. Travel duration is 12h 10m
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Cormar Bus12h 10m013:50AntofagastaCamus Coach Station02:00La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 22/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 23/08/2026 02:00:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Pullman San Andres12h 10m013:00AntofagastaCarlos Oviedo Cavada Bus Station01:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 22/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 23/08/2026 01:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 22/08/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 22/08/2026 10:50:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 10h 45m
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Cikbus Elité11h 20m003:30AntofagastaCarlos Oviedo Cavada Bus Station14:50La SerenaCentral Coach Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 22/08/2026 03:30:00 to Central Coach Station, La Serena (Chile) arriving at 22/08/2026 14:50:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 11h 20m
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LAN Perú6h 26m011:30Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:56La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 22/08/2026 11:30:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 22/08/2026 17:56:00. 50 Economy ticket for £61 per person are available. Travel duration is 6h 26m
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LATAM Brasil6h 26m011:30Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:56La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 22/08/2026 11:30:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 22/08/2026 17:56:00. 50 Economy ticket for £65 per person are available. Travel duration is 6h 26m
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LATAM Brasil23h 13m011:30Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport10:43La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 22/08/2026 11:30:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 23/08/2026 10:43:00. 50 Economy ticket for £65 per person are available. Travel duration is 23h 13m
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Sky Airline22h 57m011:50Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport10:47La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 22/08/2026 11:50:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 23/08/2026 10:47:00. 50 Economy ticket for £69 per person are available. Travel duration is 22h 57m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Pullman San Andres12h 10m013:00AntofagastaCarlos Oviedo Cavada Bus Station01:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 23/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 24/08/2026 01:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Andimar12h 10m003:35AntofagastaCarlos Oviedo Cavada Bus Station15:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 23/08/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 23/08/2026 15:45:00. 50 Economy ticket for £24 per person are available. Travel duration is 12h 10m
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FlixBus11h 35m003:00AntofagastaCarlos Oviedo Cavada Bus Station14:35La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 23/08/2026 03:00:00 to Central Coach Station, La Serena (Chile) arriving at 23/08/2026 14:35:00. 50 Economy ticket for £24 per person are available. Travel duration is 11h 35m
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Cormar Bus12h 10m013:50AntofagastaCamus Coach Station02:00La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 23/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 24/08/2026 02:00:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Cikbus Elité13h 0m008:30AntofagastaCarlos Oviedo Cavada Bus Station21:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 23/08/2026 08:30:00 to Central Coach Station, La Serena (Chile) arriving at 23/08/2026 21:30:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 13h 0m
Cheapest Buses Sunday
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Sky Airline1h 26m015:35Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:01La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 24/08/2026 15:35:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 24/08/2026 17:01:00. 50 Economy ticket for £13 per person are available. Travel duration is 1h 26m
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LATAM Brasil1h 27m007:51Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport09:18La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 24/08/2026 07:51:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 24/08/2026 09:18:00. 50 Economy ticket for £18 per person are available. Travel duration is 1h 27m
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LAN Airlines1h 27m007:51Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport09:18La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 24/08/2026 07:51:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 24/08/2026 09:18:00. 50 Economy ticket for £18 per person are available. Travel duration is 1h 27m
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LAN Perú6h 11m015:35Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport21:46La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 24/08/2026 15:35:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 24/08/2026 21:46:00. 50 Economy ticket for £36 per person are available. Travel duration is 6h 11m
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JetSmart6h 13m012:31Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport18:44La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 24/08/2026 12:31:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 24/08/2026 18:44:00. 50 Economy ticket for £38 per person are available. Travel duration is 6h 13m
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Andimar12h 10m001:35AntofagastaCarlos Oviedo Cavada Bus Station13:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 24/08/2026 01:35:00 to Central Coach Station, La Serena (Chile) arriving at 24/08/2026 13:45:00. 50 Economy ticket for £23 per person are available. Travel duration is 12h 10m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 24/08/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 24/08/2026 10:50:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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Pullman San Andres12h 10m013:00AntofagastaCarlos Oviedo Cavada Bus Station01:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 24/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 25/08/2026 01:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Cormar Bus12h 10m013:50AntofagastaCamus Coach Station02:00La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 24/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 25/08/2026 02:00:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
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Cikbus Elité12h 5m017:50AntofagastaCarlos Oviedo Cavada Bus Station05:55La SerenaCentral Coach Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 24/08/2026 17:50:00 to Central Coach Station, La Serena (Chile) arriving at 25/08/2026 05:55:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 12h 5m
Cheapest Flights Monday
Cheapest Buses Monday
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Andimar12h 10m003:35AntofagastaCarlos Oviedo Cavada Bus Station15:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 25/08/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 25/08/2026 15:45:00. 50 Economy ticket for £22 per person are available. Travel duration is 12h 10m
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FlixBus11h 35m003:00AntofagastaCarlos Oviedo Cavada Bus Station14:35La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 25/08/2026 03:00:00 to Central Coach Station, La Serena (Chile) arriving at 25/08/2026 14:35:00. 50 Economy ticket for £23 per person are available. Travel duration is 11h 35m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 25/08/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 25/08/2026 10:50:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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Pullman San Andres12h 10m013:00AntofagastaCarlos Oviedo Cavada Bus Station01:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 25/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 26/08/2026 01:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Cormar Bus12h 10m013:50AntofagastaCamus Coach Station02:00La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 25/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 26/08/2026 02:00:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
Cheapest Buses Tuesday
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Andimar12h 10m021:50AntofagastaCarlos Oviedo Cavada Bus Station10:00La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 26/08/2026 21:50:00 to Central Coach Station, La Serena (Chile) arriving at 27/08/2026 10:00:00. 50 Economy ticket for £22 per person are available. Travel duration is 12h 10m
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FlixBus11h 35m003:00AntofagastaCarlos Oviedo Cavada Bus Station14:35La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 26/08/2026 03:00:00 to Central Coach Station, La Serena (Chile) arriving at 26/08/2026 14:35:00. 50 Economy ticket for £23 per person are available. Travel duration is 11h 35m
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Cormar Bus11h 50m001:00AntofagastaCamus Coach Station12:50La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 26/08/2026 01:00:00 to Central Coach Station, La Serena (Chile) arriving at 26/08/2026 12:50:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 11h 50m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 26/08/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 26/08/2026 10:50:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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Pullman San Andres12h 10m013:00AntofagastaCarlos Oviedo Cavada Bus Station01:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 26/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 27/08/2026 01:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Sky Airline1h 26m019:36Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport21:02La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 26/08/2026 19:36:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 26/08/2026 21:02:00. 50 Economy ticket for £126 per person are available. Travel duration is 1h 26m
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LAN Airlines7h 14m023:57Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport07:11La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 26/08/2026 23:57:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 27/08/2026 07:11:00. 50 Economy ticket for £139 per person are available. Travel duration is 7h 14m
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LATAM Brasil7h 14m023:57Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport07:11La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 26/08/2026 23:57:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 27/08/2026 07:11:00. 50 Economy ticket for £148 per person are available. Travel duration is 7h 14m
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JetSmart1h 29m010:42Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport12:11La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 26/08/2026 10:42:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 26/08/2026 12:11:00. 50 Economy ticket for £157 per person are available. Travel duration is 1h 29m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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Andimar12h 10m021:50AntofagastaCarlos Oviedo Cavada Bus Station10:00La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 27/08/2026 21:50:00 to Central Coach Station, La Serena (Chile) arriving at 28/08/2026 10:00:00. 50 Economy ticket for £22 per person are available. Travel duration is 12h 10m
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Andimar12h 10m003:35AntofagastaCarlos Oviedo Cavada Bus Station15:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 27/08/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 27/08/2026 15:45:00. 50 Economy ticket for £22 per person are available. Travel duration is 12h 10m
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Pullman San Andres12h 10m013:00AntofagastaCarlos Oviedo Cavada Bus Station01:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 27/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 28/08/2026 01:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Cormar Bus12h 10m013:50AntofagastaCamus Coach Station02:00La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 27/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 28/08/2026 02:00:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
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Sky Airline1h 26m013:38Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:04La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 27/08/2026 13:38:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 27/08/2026 15:04:00. 50 Economy ticket for £27 per person are available. Travel duration is 1h 26m
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JetSmart5h 30m009:54Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:24La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 27/08/2026 09:54:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 27/08/2026 15:24:00. 50 Economy ticket for £37 per person are available. Travel duration is 5h 30m
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LATAM Brasil1h 28m013:18Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport14:46La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 27/08/2026 13:18:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 27/08/2026 14:46:00. 50 Economy ticket for £38 per person are available. Travel duration is 1h 28m
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Sky Airline6h 34m008:50Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:24La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 27/08/2026 08:50:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 27/08/2026 15:24:00. 50 Economy ticket for £38 per person are available. Travel duration is 6h 34m
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JetSmart1h 29m016:21Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:50La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 27/08/2026 16:21:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 27/08/2026 17:50:00. 50 Economy ticket for £39 per person are available. Travel duration is 1h 29m
Cheapest Buses Thursday
Cheapest Flights Thursday
What are the fastest trips from Antofagasta to La Serena?
You can get to La Serena from Antofagasta in just 1h 26m with a Flight from Sky Airline. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Sky Airline1h 26m015:03Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport16:29La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 21/08/2026 15:03:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 21/08/2026 16:29:00. 50 Economy ticket for £126 per person are available. Travel duration is 1h 26m
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JetSmart20h 50m021:06Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:56La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 21/08/2026 21:06:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 22/08/2026 17:56:00. 50 Economy ticket for £70 per person are available. Travel duration is 20h 50m
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LATAM Brasil22h 7m019:49Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:56La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 21/08/2026 19:49:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 22/08/2026 17:56:00. 50 Economy ticket for £88 per person are available. Travel duration is 22h 7m
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LAN Airlines22h 7m019:49Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:56La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 21/08/2026 19:49:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 22/08/2026 17:56:00. 50 Economy ticket for £89 per person are available. Travel duration is 22h 7m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 21/08/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 21/08/2026 10:50:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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Cikbus Elité11h 25m013:35AntofagastaCarlos Oviedo Cavada Bus Station01:00La SerenaCentral Coach Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 21/08/2026 13:35:00 to Central Coach Station, La Serena (Chile) arriving at 22/08/2026 01:00:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 11h 25m
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Pullman San Andres12h 10m013:00AntofagastaCarlos Oviedo Cavada Bus Station01:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 21/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 22/08/2026 01:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Cormar Bus12h 10m013:50AntofagastaCamus Coach Station02:00La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 21/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 22/08/2026 02:00:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Andimar12h 10m021:50AntofagastaCarlos Oviedo Cavada Bus Station10:00La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 21/08/2026 21:50:00 to Central Coach Station, La Serena (Chile) arriving at 22/08/2026 10:00:00. 50 Economy ticket for £25 per person are available. Travel duration is 12h 10m
Fastest Flights Friday
Fastest Buses Friday
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LAN Perú6h 26m011:30Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:56La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 22/08/2026 11:30:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 22/08/2026 17:56:00. 50 Economy ticket for £61 per person are available. Travel duration is 6h 26m
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LATAM Brasil6h 26m011:30Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:56La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 22/08/2026 11:30:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 22/08/2026 17:56:00. 50 Economy ticket for £65 per person are available. Travel duration is 6h 26m
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Sky Airline22h 57m011:50Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport10:47La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 22/08/2026 11:50:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 23/08/2026 10:47:00. 50 Economy ticket for £69 per person are available. Travel duration is 22h 57m
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LATAM Brasil23h 13m011:30Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport10:43La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 22/08/2026 11:30:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 23/08/2026 10:43:00. 50 Economy ticket for £65 per person are available. Travel duration is 23h 13m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 22/08/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 22/08/2026 10:50:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 10h 45m
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Cikbus Elité11h 20m003:30AntofagastaCarlos Oviedo Cavada Bus Station14:50La SerenaCentral Coach Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 22/08/2026 03:30:00 to Central Coach Station, La Serena (Chile) arriving at 22/08/2026 14:50:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 11h 20m
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Andimar12h 10m003:35AntofagastaCarlos Oviedo Cavada Bus Station15:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 22/08/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 22/08/2026 15:45:00. 50 Economy ticket for £23 per person are available. Travel duration is 12h 10m
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Cormar Bus12h 10m013:50AntofagastaCamus Coach Station02:00La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 22/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 23/08/2026 02:00:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Pullman San Andres12h 10m013:00AntofagastaCarlos Oviedo Cavada Bus Station01:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 22/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 23/08/2026 01:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
Fastest Flights Saturday
Fastest Buses Saturday
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FlixBus11h 35m003:00AntofagastaCarlos Oviedo Cavada Bus Station14:35La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 23/08/2026 03:00:00 to Central Coach Station, La Serena (Chile) arriving at 23/08/2026 14:35:00. 50 Economy ticket for £24 per person are available. Travel duration is 11h 35m
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Pullman San Andres12h 10m013:00AntofagastaCarlos Oviedo Cavada Bus Station01:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 23/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 24/08/2026 01:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Andimar12h 10m003:35AntofagastaCarlos Oviedo Cavada Bus Station15:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 23/08/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 23/08/2026 15:45:00. 50 Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Cormar Bus12h 10m013:50AntofagastaCamus Coach Station02:00La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 23/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 24/08/2026 02:00:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Cikbus Elité13h 0m008:30AntofagastaCarlos Oviedo Cavada Bus Station21:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 23/08/2026 08:30:00 to Central Coach Station, La Serena (Chile) arriving at 23/08/2026 21:30:00. 50 Premium Economy ticket for £28 per person are available. Travel duration is 13h 0m
Fastest Buses Sunday
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Sky Airline1h 26m015:35Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:01La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 24/08/2026 15:35:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 24/08/2026 17:01:00. 50 Economy ticket for £13 per person are available. Travel duration is 1h 26m
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LATAM Brasil1h 27m007:51Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport09:18La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 24/08/2026 07:51:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 24/08/2026 09:18:00. 50 Economy ticket for £18 per person are available. Travel duration is 1h 27m
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LAN Airlines1h 27m007:51Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport09:18La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 24/08/2026 07:51:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 24/08/2026 09:18:00. 50 Economy ticket for £18 per person are available. Travel duration is 1h 27m
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LAN Perú6h 11m015:35Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport21:46La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 24/08/2026 15:35:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 24/08/2026 21:46:00. 50 Economy ticket for £36 per person are available. Travel duration is 6h 11m
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JetSmart6h 13m012:31Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport18:44La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 24/08/2026 12:31:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 24/08/2026 18:44:00. 50 Economy ticket for £38 per person are available. Travel duration is 6h 13m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 24/08/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 24/08/2026 10:50:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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Cikbus Elité12h 5m017:50AntofagastaCarlos Oviedo Cavada Bus Station05:55La SerenaCentral Coach Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 24/08/2026 17:50:00 to Central Coach Station, La Serena (Chile) arriving at 25/08/2026 05:55:00. 50 Premium Economy ticket for £27 per person are available. Travel duration is 12h 5m
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Andimar12h 10m001:35AntofagastaCarlos Oviedo Cavada Bus Station13:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 24/08/2026 01:35:00 to Central Coach Station, La Serena (Chile) arriving at 24/08/2026 13:45:00. 50 Economy ticket for £23 per person are available. Travel duration is 12h 10m
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Pullman San Andres12h 10m013:00AntofagastaCarlos Oviedo Cavada Bus Station01:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 24/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 25/08/2026 01:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Cormar Bus12h 10m013:50AntofagastaCamus Coach Station02:00La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 24/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 25/08/2026 02:00:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
Fastest Flights Monday
Fastest Buses Monday
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 25/08/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 25/08/2026 10:50:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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FlixBus11h 35m003:00AntofagastaCarlos Oviedo Cavada Bus Station14:35La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 25/08/2026 03:00:00 to Central Coach Station, La Serena (Chile) arriving at 25/08/2026 14:35:00. 50 Economy ticket for £23 per person are available. Travel duration is 11h 35m
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Andimar12h 10m003:35AntofagastaCarlos Oviedo Cavada Bus Station15:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 25/08/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 25/08/2026 15:45:00. 50 Economy ticket for £22 per person are available. Travel duration is 12h 10m
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Pullman San Andres12h 10m013:00AntofagastaCarlos Oviedo Cavada Bus Station01:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 25/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 26/08/2026 01:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Cormar Bus12h 10m013:50AntofagastaCamus Coach Station02:00La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 25/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 26/08/2026 02:00:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
Fastest Buses Tuesday
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Sky Airline1h 26m019:36Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport21:02La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 26/08/2026 19:36:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 26/08/2026 21:02:00. 50 Economy ticket for £126 per person are available. Travel duration is 1h 26m
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JetSmart1h 29m010:42Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport12:11La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 26/08/2026 10:42:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 26/08/2026 12:11:00. 50 Economy ticket for £157 per person are available. Travel duration is 1h 29m
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LAN Airlines7h 14m023:57Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport07:11La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 26/08/2026 23:57:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 27/08/2026 07:11:00. 50 Economy ticket for £139 per person are available. Travel duration is 7h 14m
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LATAM Brasil7h 14m023:57Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport07:11La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 26/08/2026 23:57:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 27/08/2026 07:11:00. 50 Economy ticket for £148 per person are available. Travel duration is 7h 14m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 26/08/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 26/08/2026 10:50:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 10h 45m
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FlixBus11h 35m003:00AntofagastaCarlos Oviedo Cavada Bus Station14:35La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 26/08/2026 03:00:00 to Central Coach Station, La Serena (Chile) arriving at 26/08/2026 14:35:00. 50 Economy ticket for £23 per person are available. Travel duration is 11h 35m
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Cormar Bus11h 50m001:00AntofagastaCamus Coach Station12:50La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 26/08/2026 01:00:00 to Central Coach Station, La Serena (Chile) arriving at 26/08/2026 12:50:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 11h 50m
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Andimar12h 10m021:50AntofagastaCarlos Oviedo Cavada Bus Station10:00La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 26/08/2026 21:50:00 to Central Coach Station, La Serena (Chile) arriving at 27/08/2026 10:00:00. 50 Economy ticket for £22 per person are available. Travel duration is 12h 10m
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Pullman San Andres12h 10m013:00AntofagastaCarlos Oviedo Cavada Bus Station01:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 26/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 27/08/2026 01:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
Fastest Flights Wednesday
Fastest Buses Wednesday
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Sky Airline1h 26m013:38Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:04La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 27/08/2026 13:38:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 27/08/2026 15:04:00. 50 Economy ticket for £27 per person are available. Travel duration is 1h 26m
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LATAM Brasil1h 28m013:18Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport14:46La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 27/08/2026 13:18:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 27/08/2026 14:46:00. 50 Economy ticket for £38 per person are available. Travel duration is 1h 28m
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JetSmart1h 29m016:21Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:50La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 27/08/2026 16:21:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 27/08/2026 17:50:00. 50 Economy ticket for £39 per person are available. Travel duration is 1h 29m
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JetSmart5h 30m009:54Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:24La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 27/08/2026 09:54:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 27/08/2026 15:24:00. 50 Economy ticket for £37 per person are available. Travel duration is 5h 30m
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Sky Airline6h 34m008:50Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:24La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 27/08/2026 08:50:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 27/08/2026 15:24:00. 50 Economy ticket for £38 per person are available. Travel duration is 6h 34m
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Andimar12h 10m021:50AntofagastaCarlos Oviedo Cavada Bus Station10:00La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 27/08/2026 21:50:00 to Central Coach Station, La Serena (Chile) arriving at 28/08/2026 10:00:00. 50 Economy ticket for £22 per person are available. Travel duration is 12h 10m
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Andimar12h 10m003:35AntofagastaCarlos Oviedo Cavada Bus Station15:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 27/08/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 27/08/2026 15:45:00. 50 Economy ticket for £22 per person are available. Travel duration is 12h 10m
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Pullman San Andres12h 10m013:00AntofagastaCarlos Oviedo Cavada Bus Station01:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 27/08/2026 13:00:00 to Central Coach Station, La Serena (Chile) arriving at 28/08/2026 01:10:00. 50 Premium Economy ticket for £24 per person are available. Travel duration is 12h 10m
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Cormar Bus12h 10m013:50AntofagastaCamus Coach Station02:00La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 27/08/2026 13:50:00 to Central Coach Station, La Serena (Chile) arriving at 28/08/2026 02:00:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 12h 10m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Antofagasta to La Serena
What are the most popular stations in Antofagasta and La Serena?
In Antofagasta, you will usually depart from Maipú, Camus Coach Station or Carlos Oviedo Cavada Bus Station, while in La Serena you will be arriving at Avda. Fco de Aguirre Station, El Sto, 1060 or Central Coach Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to La Serena from Antofagasta? With 8 connections between 8 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Antofagasta and La Serena, you can pay as low as £13 with a Flight from Sky Airline.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Sky Airline: you will get to La Serena in just 1h 26m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Antofagasta and La Serena are Pullman San Andres, Andimar and Sky Airline, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Antofagasta and La Serena is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from La Negra or to La Florida, La Serena Airport, and look at flights from Andrés Sabella Gálvez, Antofagasta Airport, and landing at La Florida, La Serena Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Antofagasta to La Serena?
The most popular companies between Antofagasta and La Serena, are Pullman San Andres, Andimar and Sky Airline. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Pullman San Andres, Andimar, Cormar Bus and 3 more.
Airlines: Sky Airline, JetSmart, LATAM Brasil and 2 more.
All you need to know when you travel from Antofagasta to La Serena
Check all information on comfort and services on all modes of transports from Antofagasta to La Serena. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Antofagasta to La Serena
How can I reach La Serena from Antofagasta?
Every day, there are on average 8 connections between Flight and Bus, with which you can get to La Serena from Antofagasta.
How far is La Serena from Antofagasta?
The distance between Antofagasta and La Serena is 700.4 km.
What is the most ecofriendly mode of transport between Antofagasta and La Serena?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 119 kgs, and a flight 172 kgs.
What is the cheapest mode of transport from Antofagasta to La Serena?
You can get to La Serena with just £13 by taking a Flight from Sky Airline.
What is the fastest way to get from Antofagasta to La Serena?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to La Serena in just 1h 26m with a Flight from Sky Airline.
More routes to Antofagasta and to La Serena
Looking for more options? Here you can see the most popular routes to Antofagasta and to La Serena. Simply click on a connection, and you’ll find all the details about the route!
