What is the best way to travel from Antofagasta to La Serena?
Looking for a trip? Check and compare all the available Flights and Buses to La Serena from Antofagasta. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 7 available companies to find your perfect trip!
What is the cheapest way to reach La Serena from Antofagasta?
You can reach La Serena with just £19 by taking a Bus from Andimar, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Andimar12h 10m021:50AntofagastaCarlos Oviedo Cavada Bus Station10:00La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 04/10/2026 21:50:00 to Central Coach Station, La Serena (Chile) arriving at 05/10/2026 10:00:00. 50 Economy ticket for £22 per person are available. Travel duration is 12h 10m
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Pluss Chile10h 45m004:31AntofagastaCarlos Oviedo Cavada Bus Station15:16La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 04/10/2026 04:31:00 to Central Coach Station, La Serena (Chile) arriving at 04/10/2026 15:16:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 10h 45m
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Cormar Bus12h 0m013:30AntofagastaCamus Coach Station01:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 04/10/2026 13:30:00 to Central Coach Station, La Serena (Chile) arriving at 05/10/2026 01:30:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 12h 0m
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Pullman San Andres12h 10m017:30AntofagastaCarlos Oviedo Cavada Bus Station05:40La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 04/10/2026 17:30:00 to Central Coach Station, La Serena (Chile) arriving at 05/10/2026 05:40:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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Pullman Bus11h 35m010:30AntofagastaCamus Coach Station22:05La SerenaEl Sto, 10600First ClassA Bus from Pullman Bus goes from Camus Coach Station, Antofagasta (Chile) at 04/10/2026 10:30:00 to El Sto, 1060, La Serena (Chile) arriving at 04/10/2026 22:05:00. 50 First Class ticket for £28 per person are available. Travel duration is 11h 35m
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JetSmart1h 29m018:01Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport19:30La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 04/10/2026 18:01:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 04/10/2026 19:30:00. 50 Economy ticket for £34 per person are available. Travel duration is 1h 29m
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LATAM Brasil1h 25m016:53Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport18:18La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 04/10/2026 16:53:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 04/10/2026 18:18:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 25m
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Sky Airline1h 24m021:09Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport22:33La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 04/10/2026 21:09:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 04/10/2026 22:33:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 24m
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LAN Airlines1h 25m016:53Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport18:18La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 04/10/2026 16:53:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 04/10/2026 18:18:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 25m
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LAN Perú4h 16m012:08Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport16:24La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 04/10/2026 12:08:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 04/10/2026 16:24:00. 50 Economy ticket for £186 per person are available. Travel duration is 4h 16m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Andimar12h 10m021:50AntofagastaCarlos Oviedo Cavada Bus Station10:00La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/10/2026 21:50:00 to Central Coach Station, La Serena (Chile) arriving at 06/10/2026 10:00:00. 50 Economy ticket for £22 per person are available. Travel duration is 12h 10m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/10/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 05/10/2026 10:50:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 10h 45m
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Cormar Bus11h 50m000:30AntofagastaCamus Coach Station12:20La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 05/10/2026 00:30:00 to Central Coach Station, La Serena (Chile) arriving at 05/10/2026 12:20:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 11h 50m
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Pullman San Andres12h 10m012:00AntofagastaCarlos Oviedo Cavada Bus Station00:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/10/2026 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 06/10/2026 00:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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Cikbus Elité11h 20m001:10AntofagastaCarlos Oviedo Cavada Bus Station12:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/10/2026 01:10:00 to Central Coach Station, La Serena (Chile) arriving at 05/10/2026 12:30:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 11h 20m
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JetSmart1h 29m016:23Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:52La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 05/10/2026 16:23:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 05/10/2026 17:52:00. 50 Economy ticket for £30 per person are available. Travel duration is 1h 29m
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Sky Airline1h 24m014:24Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:48La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 05/10/2026 14:24:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 05/10/2026 15:48:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 24m
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LAN Airlines1h 26m008:10Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport09:36La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 05/10/2026 08:10:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 05/10/2026 09:36:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 26m
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LATAM Brasil1h 26m008:10Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport09:36La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 05/10/2026 08:10:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 05/10/2026 09:36:00. 50 Economy ticket for £38 per person are available. Travel duration is 1h 26m
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LAN Perú7h 0m009:05Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport16:05La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 05/10/2026 09:05:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 05/10/2026 16:05:00. 50 Economy ticket for £57 per person are available. Travel duration is 7h 0m
Cheapest Buses Monday
Cheapest Flights Monday
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FlixBus11h 35m003:00AntofagastaCarlos Oviedo Cavada Bus Station14:35La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/10/2026 03:00:00 to Central Coach Station, La Serena (Chile) arriving at 06/10/2026 14:35:00. 50 Economy ticket for £20 per person are available. Travel duration is 11h 35m
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Andimar12h 10m001:35AntofagastaCarlos Oviedo Cavada Bus Station13:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/10/2026 01:35:00 to Central Coach Station, La Serena (Chile) arriving at 06/10/2026 13:45:00. 50 Economy ticket for £21 per person are available. Travel duration is 12h 10m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/10/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 06/10/2026 10:50:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 10h 45m
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Cormar Bus11h 50m000:30AntofagastaCamus Coach Station12:20La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 06/10/2026 00:30:00 to Central Coach Station, La Serena (Chile) arriving at 06/10/2026 12:20:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 11h 50m
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Pullman San Andres12h 10m012:00AntofagastaCarlos Oviedo Cavada Bus Station00:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/10/2026 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 07/10/2026 00:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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JetSmart1h 29m009:17Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport10:46La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 06/10/2026 09:17:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 06/10/2026 10:46:00. 50 Economy ticket for £38 per person are available. Travel duration is 1h 29m
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LAN Airlines1h 27m009:16Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport10:43La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 06/10/2026 09:16:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 06/10/2026 10:43:00. 50 Economy ticket for £46 per person are available. Travel duration is 1h 27m
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LATAM Brasil1h 27m009:16Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport10:43La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 06/10/2026 09:16:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 06/10/2026 10:43:00. 50 Economy ticket for £49 per person are available. Travel duration is 1h 27m
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LAN Perú5h 2m007:15Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport12:17La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 06/10/2026 07:15:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 06/10/2026 12:17:00. 50 Economy ticket for £113 per person are available. Travel duration is 5h 2m
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Sky Airline26h 7m008:40Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport10:47La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 06/10/2026 08:40:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 07/10/2026 10:47:00. 50 Economy ticket for £124 per person are available. Travel duration is 26h 7m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Andimar12h 10m003:35AntofagastaCarlos Oviedo Cavada Bus Station15:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/10/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 07/10/2026 15:45:00. 50 Economy ticket for £20 per person are available. Travel duration is 12h 10m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/10/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 07/10/2026 10:50:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 10h 45m
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FlixBus11h 35m003:00AntofagastaCarlos Oviedo Cavada Bus Station14:35La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/10/2026 03:00:00 to Central Coach Station, La Serena (Chile) arriving at 07/10/2026 14:35:00. 50 Economy ticket for £23 per person are available. Travel duration is 11h 35m
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Cormar Bus11h 50m000:30AntofagastaCamus Coach Station12:20La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 07/10/2026 00:30:00 to Central Coach Station, La Serena (Chile) arriving at 07/10/2026 12:20:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 11h 50m
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Pullman San Andres12h 10m012:00AntofagastaCarlos Oviedo Cavada Bus Station00:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/10/2026 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 08/10/2026 00:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
Cheapest Buses Wednesday
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Andimar12h 10m003:35AntofagastaCarlos Oviedo Cavada Bus Station15:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 08/10/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 08/10/2026 15:45:00. 50 Economy ticket for £20 per person are available. Travel duration is 12h 10m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 08/10/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 08/10/2026 10:50:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 10h 45m
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Cormar Bus11h 50m000:30AntofagastaCamus Coach Station12:20La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 08/10/2026 00:30:00 to Central Coach Station, La Serena (Chile) arriving at 08/10/2026 12:20:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 11h 50m
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Pullman San Andres12h 10m004:30AntofagastaCarlos Oviedo Cavada Bus Station16:40La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 08/10/2026 04:30:00 to Central Coach Station, La Serena (Chile) arriving at 08/10/2026 16:40:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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Cikbus Elité13h 0m008:30AntofagastaCarlos Oviedo Cavada Bus Station21:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 08/10/2026 08:30:00 to Central Coach Station, La Serena (Chile) arriving at 08/10/2026 21:30:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 13h 0m
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JetSmart1h 29m009:37Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport11:06La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 08/10/2026 09:37:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 08/10/2026 11:06:00. 50 Economy ticket for £32 per person are available. Travel duration is 1h 29m
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LAN Airlines1h 25m013:42Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:07La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 08/10/2026 13:42:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 08/10/2026 15:07:00. 50 Economy ticket for £99 per person are available. Travel duration is 1h 25m
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LATAM Brasil1h 25m013:42Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:07La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 08/10/2026 13:42:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 08/10/2026 15:07:00. 50 Economy ticket for £113 per person are available. Travel duration is 1h 25m
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Sky Airline1h 24m019:57Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport21:21La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 08/10/2026 19:57:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 08/10/2026 21:21:00. 50 Economy ticket for £146 per person are available. Travel duration is 1h 24m
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LAN Perú5h 40m009:49Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:29La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 08/10/2026 09:49:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 08/10/2026 15:29:00. 50 Economy ticket for £170 per person are available. Travel duration is 5h 40m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Andimar12h 10m001:35AntofagastaCarlos Oviedo Cavada Bus Station13:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 09/10/2026 01:35:00 to Central Coach Station, La Serena (Chile) arriving at 09/10/2026 13:45:00. 50 Economy ticket for £21 per person are available. Travel duration is 12h 10m
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FlixBus11h 35m003:00AntofagastaCarlos Oviedo Cavada Bus Station14:35La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 09/10/2026 03:00:00 to Central Coach Station, La Serena (Chile) arriving at 09/10/2026 14:35:00. 50 Economy ticket for £21 per person are available. Travel duration is 11h 35m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 09/10/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 09/10/2026 10:50:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 10h 45m
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Cormar Bus12h 0m013:30AntofagastaCamus Coach Station01:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 09/10/2026 13:30:00 to Central Coach Station, La Serena (Chile) arriving at 10/10/2026 01:30:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 12h 0m
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Pullman San Andres12h 10m012:00AntofagastaCarlos Oviedo Cavada Bus Station00:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 09/10/2026 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 10/10/2026 00:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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JetSmart1h 29m008:03Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport09:32La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 09/10/2026 08:03:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 09/10/2026 09:32:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 29m
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Sky Airline1h 24m013:46Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:10La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 09/10/2026 13:46:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 09/10/2026 15:10:00. 50 Economy ticket for £93 per person are available. Travel duration is 1h 24m
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LAN Airlines1h 25m013:48Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:13La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 09/10/2026 13:48:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 09/10/2026 15:13:00. 50 Economy ticket for £99 per person are available. Travel duration is 1h 25m
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LATAM Brasil1h 25m013:48Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:13La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 09/10/2026 13:48:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 09/10/2026 15:13:00. 50 Economy ticket for £113 per person are available. Travel duration is 1h 25m
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LAN Perú6h 14m007:24Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport13:38La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 09/10/2026 07:24:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 09/10/2026 13:38:00. 50 Economy ticket for £164 per person are available. Travel duration is 6h 14m
Cheapest Buses Friday
Cheapest Flights Friday
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Andimar12h 10m003:35AntofagastaCarlos Oviedo Cavada Bus Station15:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 10/10/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 10/10/2026 15:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 12h 10m
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Andimar12h 10m021:50AntofagastaCarlos Oviedo Cavada Bus Station10:00La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 10/10/2026 21:50:00 to Central Coach Station, La Serena (Chile) arriving at 11/10/2026 10:00:00. 50 Economy ticket for £19 per person are available. Travel duration is 12h 10m
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Cormar Bus12h 0m013:30AntofagastaCamus Coach Station01:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 10/10/2026 13:30:00 to Central Coach Station, La Serena (Chile) arriving at 11/10/2026 01:30:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 12h 0m
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Cormar Bus11h 50m000:30AntofagastaCamus Coach Station12:20La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 10/10/2026 00:30:00 to Central Coach Station, La Serena (Chile) arriving at 10/10/2026 12:20:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 11h 50m
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Pullman San Andres12h 10m012:00AntofagastaCarlos Oviedo Cavada Bus Station00:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 10/10/2026 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 11/10/2026 00:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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JetSmart12h 14m020:53Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport09:07La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 10/10/2026 20:53:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 11/10/2026 09:07:00. 50 Economy ticket for £54 per person are available. Travel duration is 12h 14m
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JetSmart15h 29m020:53Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport12:22La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 10/10/2026 20:53:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 11/10/2026 12:22:00. 50 Economy ticket for £57 per person are available. Travel duration is 15h 29m
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Sky Airline23h 14m013:08Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport12:22La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 10/10/2026 13:08:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 11/10/2026 12:22:00. 50 Economy ticket for £73 per person are available. Travel duration is 23h 14m
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LATAM Brasil20h 38m015:44Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport12:22La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 10/10/2026 15:44:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 11/10/2026 12:22:00. 50 Economy ticket for £74 per person are available. Travel duration is 20h 38m
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LATAM Brasil16h 19m020:03Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport12:22La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 10/10/2026 20:03:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 11/10/2026 12:22:00. 50 Economy ticket for £74 per person are available. Travel duration is 16h 19m
Cheapest Buses Saturday
Cheapest Flights Saturday
What are the fastest trips from Antofagasta to La Serena?
You can get to La Serena from Antofagasta in just 1h 24m with a Flight from Sky Airline. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Sky Airline1h 24m021:09Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport22:33La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 04/10/2026 21:09:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 04/10/2026 22:33:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 24m
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LATAM Brasil1h 25m016:53Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport18:18La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 04/10/2026 16:53:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 04/10/2026 18:18:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 25m
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LAN Airlines1h 25m016:53Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport18:18La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 04/10/2026 16:53:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 04/10/2026 18:18:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 25m
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JetSmart1h 29m018:01Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport19:30La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 04/10/2026 18:01:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 04/10/2026 19:30:00. 50 Economy ticket for £34 per person are available. Travel duration is 1h 29m
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LAN Perú4h 16m012:08Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport16:24La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 04/10/2026 12:08:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 04/10/2026 16:24:00. 50 Economy ticket for £186 per person are available. Travel duration is 4h 16m
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Pluss Chile10h 45m004:31AntofagastaCarlos Oviedo Cavada Bus Station15:16La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 04/10/2026 04:31:00 to Central Coach Station, La Serena (Chile) arriving at 04/10/2026 15:16:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 10h 45m
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Pullman Bus11h 35m010:30AntofagastaCamus Coach Station22:05La SerenaEl Sto, 10600First ClassA Bus from Pullman Bus goes from Camus Coach Station, Antofagasta (Chile) at 04/10/2026 10:30:00 to El Sto, 1060, La Serena (Chile) arriving at 04/10/2026 22:05:00. 50 First Class ticket for £28 per person are available. Travel duration is 11h 35m
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Cormar Bus12h 0m013:30AntofagastaCamus Coach Station01:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 04/10/2026 13:30:00 to Central Coach Station, La Serena (Chile) arriving at 05/10/2026 01:30:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 12h 0m
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Andimar12h 10m021:50AntofagastaCarlos Oviedo Cavada Bus Station10:00La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 04/10/2026 21:50:00 to Central Coach Station, La Serena (Chile) arriving at 05/10/2026 10:00:00. 50 Economy ticket for £22 per person are available. Travel duration is 12h 10m
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Pullman San Andres12h 10m017:30AntofagastaCarlos Oviedo Cavada Bus Station05:40La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 04/10/2026 17:30:00 to Central Coach Station, La Serena (Chile) arriving at 05/10/2026 05:40:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
Fastest Flights Sunday
Fastest Buses Sunday
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Sky Airline1h 24m014:24Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:48La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 05/10/2026 14:24:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 05/10/2026 15:48:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 24m
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LAN Airlines1h 26m008:10Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport09:36La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 05/10/2026 08:10:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 05/10/2026 09:36:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 26m
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LATAM Brasil1h 26m008:10Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport09:36La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 05/10/2026 08:10:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 05/10/2026 09:36:00. 50 Economy ticket for £38 per person are available. Travel duration is 1h 26m
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JetSmart1h 29m016:23Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport17:52La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 05/10/2026 16:23:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 05/10/2026 17:52:00. 50 Economy ticket for £30 per person are available. Travel duration is 1h 29m
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LAN Perú7h 0m009:05Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport16:05La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 05/10/2026 09:05:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 05/10/2026 16:05:00. 50 Economy ticket for £57 per person are available. Travel duration is 7h 0m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/10/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 05/10/2026 10:50:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 10h 45m
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Cikbus Elité11h 20m001:10AntofagastaCarlos Oviedo Cavada Bus Station12:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/10/2026 01:10:00 to Central Coach Station, La Serena (Chile) arriving at 05/10/2026 12:30:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 11h 20m
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Cormar Bus11h 50m000:30AntofagastaCamus Coach Station12:20La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 05/10/2026 00:30:00 to Central Coach Station, La Serena (Chile) arriving at 05/10/2026 12:20:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 11h 50m
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Andimar12h 10m021:50AntofagastaCarlos Oviedo Cavada Bus Station10:00La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/10/2026 21:50:00 to Central Coach Station, La Serena (Chile) arriving at 06/10/2026 10:00:00. 50 Economy ticket for £22 per person are available. Travel duration is 12h 10m
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Pullman San Andres12h 10m012:00AntofagastaCarlos Oviedo Cavada Bus Station00:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 05/10/2026 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 06/10/2026 00:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
Fastest Flights Monday
Fastest Buses Monday
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LAN Airlines1h 27m009:16Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport10:43La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 06/10/2026 09:16:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 06/10/2026 10:43:00. 50 Economy ticket for £46 per person are available. Travel duration is 1h 27m
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LATAM Brasil1h 27m009:16Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport10:43La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 06/10/2026 09:16:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 06/10/2026 10:43:00. 50 Economy ticket for £49 per person are available. Travel duration is 1h 27m
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JetSmart1h 29m009:17Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport10:46La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 06/10/2026 09:17:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 06/10/2026 10:46:00. 50 Economy ticket for £38 per person are available. Travel duration is 1h 29m
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LAN Perú5h 2m007:15Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport12:17La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 06/10/2026 07:15:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 06/10/2026 12:17:00. 50 Economy ticket for £113 per person are available. Travel duration is 5h 2m
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Sky Airline26h 7m008:40Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport10:47La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 06/10/2026 08:40:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 07/10/2026 10:47:00. 50 Economy ticket for £124 per person are available. Travel duration is 26h 7m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/10/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 06/10/2026 10:50:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 10h 45m
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FlixBus11h 35m003:00AntofagastaCarlos Oviedo Cavada Bus Station14:35La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/10/2026 03:00:00 to Central Coach Station, La Serena (Chile) arriving at 06/10/2026 14:35:00. 50 Economy ticket for £20 per person are available. Travel duration is 11h 35m
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Cormar Bus11h 50m000:30AntofagastaCamus Coach Station12:20La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 06/10/2026 00:30:00 to Central Coach Station, La Serena (Chile) arriving at 06/10/2026 12:20:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 11h 50m
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Andimar12h 10m001:35AntofagastaCarlos Oviedo Cavada Bus Station13:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/10/2026 01:35:00 to Central Coach Station, La Serena (Chile) arriving at 06/10/2026 13:45:00. 50 Economy ticket for £21 per person are available. Travel duration is 12h 10m
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Pullman San Andres12h 10m012:00AntofagastaCarlos Oviedo Cavada Bus Station00:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 06/10/2026 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 07/10/2026 00:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/10/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 07/10/2026 10:50:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 10h 45m
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FlixBus11h 35m003:00AntofagastaCarlos Oviedo Cavada Bus Station14:35La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/10/2026 03:00:00 to Central Coach Station, La Serena (Chile) arriving at 07/10/2026 14:35:00. 50 Economy ticket for £23 per person are available. Travel duration is 11h 35m
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Cormar Bus11h 50m000:30AntofagastaCamus Coach Station12:20La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 07/10/2026 00:30:00 to Central Coach Station, La Serena (Chile) arriving at 07/10/2026 12:20:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 11h 50m
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Andimar12h 10m003:35AntofagastaCarlos Oviedo Cavada Bus Station15:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/10/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 07/10/2026 15:45:00. 50 Economy ticket for £20 per person are available. Travel duration is 12h 10m
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Pullman San Andres12h 10m012:00AntofagastaCarlos Oviedo Cavada Bus Station00:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 07/10/2026 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 08/10/2026 00:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
Fastest Buses Wednesday
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Sky Airline1h 24m019:57Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport21:21La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 08/10/2026 19:57:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 08/10/2026 21:21:00. 50 Economy ticket for £146 per person are available. Travel duration is 1h 24m
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LAN Airlines1h 25m013:42Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:07La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 08/10/2026 13:42:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 08/10/2026 15:07:00. 50 Economy ticket for £99 per person are available. Travel duration is 1h 25m
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LATAM Brasil1h 25m013:42Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:07La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 08/10/2026 13:42:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 08/10/2026 15:07:00. 50 Economy ticket for £113 per person are available. Travel duration is 1h 25m
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JetSmart1h 29m009:37Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport11:06La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 08/10/2026 09:37:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 08/10/2026 11:06:00. 50 Economy ticket for £32 per person are available. Travel duration is 1h 29m
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LAN Perú5h 40m009:49Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:29La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 08/10/2026 09:49:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 08/10/2026 15:29:00. 50 Economy ticket for £170 per person are available. Travel duration is 5h 40m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 08/10/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 08/10/2026 10:50:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 10h 45m
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Cormar Bus11h 50m000:30AntofagastaCamus Coach Station12:20La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 08/10/2026 00:30:00 to Central Coach Station, La Serena (Chile) arriving at 08/10/2026 12:20:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 11h 50m
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Andimar12h 10m003:35AntofagastaCarlos Oviedo Cavada Bus Station15:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 08/10/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 08/10/2026 15:45:00. 50 Economy ticket for £20 per person are available. Travel duration is 12h 10m
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Pullman San Andres12h 10m004:30AntofagastaCarlos Oviedo Cavada Bus Station16:40La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 08/10/2026 04:30:00 to Central Coach Station, La Serena (Chile) arriving at 08/10/2026 16:40:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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Cikbus Elité13h 0m008:30AntofagastaCarlos Oviedo Cavada Bus Station21:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cikbus Elité goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 08/10/2026 08:30:00 to Central Coach Station, La Serena (Chile) arriving at 08/10/2026 21:30:00. 50 Premium Economy ticket for £26 per person are available. Travel duration is 13h 0m
Fastest Flights Thursday
Fastest Buses Thursday
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Sky Airline1h 24m013:46Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:10La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 09/10/2026 13:46:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 09/10/2026 15:10:00. 50 Economy ticket for £93 per person are available. Travel duration is 1h 24m
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LAN Airlines1h 25m013:48Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:13La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Airlines goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 09/10/2026 13:48:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 09/10/2026 15:13:00. 50 Economy ticket for £99 per person are available. Travel duration is 1h 25m
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LATAM Brasil1h 25m013:48Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport15:13La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 09/10/2026 13:48:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 09/10/2026 15:13:00. 50 Economy ticket for £113 per person are available. Travel duration is 1h 25m
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JetSmart1h 29m008:03Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport09:32La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 09/10/2026 08:03:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 09/10/2026 09:32:00. 50 Economy ticket for £37 per person are available. Travel duration is 1h 29m
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LAN Perú6h 14m007:24Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport13:38La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LAN Perú goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 09/10/2026 07:24:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 09/10/2026 13:38:00. 50 Economy ticket for £164 per person are available. Travel duration is 6h 14m
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Pluss Chile10h 45m000:05AntofagastaCarlos Oviedo Cavada Bus Station10:50La SerenaCentral Coach Station0Premium EconomyA Bus from Pluss Chile goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 09/10/2026 00:05:00 to Central Coach Station, La Serena (Chile) arriving at 09/10/2026 10:50:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 10h 45m
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FlixBus11h 35m003:00AntofagastaCarlos Oviedo Cavada Bus Station14:35La SerenaCentral Coach Station0EconomyA Bus from FlixBus goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 09/10/2026 03:00:00 to Central Coach Station, La Serena (Chile) arriving at 09/10/2026 14:35:00. 50 Economy ticket for £21 per person are available. Travel duration is 11h 35m
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Cormar Bus12h 0m013:30AntofagastaCamus Coach Station01:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 09/10/2026 13:30:00 to Central Coach Station, La Serena (Chile) arriving at 10/10/2026 01:30:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 12h 0m
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Andimar12h 10m001:35AntofagastaCarlos Oviedo Cavada Bus Station13:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 09/10/2026 01:35:00 to Central Coach Station, La Serena (Chile) arriving at 09/10/2026 13:45:00. 50 Economy ticket for £21 per person are available. Travel duration is 12h 10m
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Pullman San Andres12h 10m012:00AntofagastaCarlos Oviedo Cavada Bus Station00:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 09/10/2026 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 10/10/2026 00:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
Fastest Flights Friday
Fastest Buses Friday
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Cormar Bus11h 50m000:30AntofagastaCamus Coach Station12:20La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 10/10/2026 00:30:00 to Central Coach Station, La Serena (Chile) arriving at 10/10/2026 12:20:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 11h 50m
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Cormar Bus12h 0m013:30AntofagastaCamus Coach Station01:30La SerenaCentral Coach Station0Premium EconomyA Bus from Cormar Bus goes from Camus Coach Station, Antofagasta (Chile) at 10/10/2026 13:30:00 to Central Coach Station, La Serena (Chile) arriving at 11/10/2026 01:30:00. 50 Premium Economy ticket for £23 per person are available. Travel duration is 12h 0m
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Andimar12h 10m003:35AntofagastaCarlos Oviedo Cavada Bus Station15:45La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 10/10/2026 03:35:00 to Central Coach Station, La Serena (Chile) arriving at 10/10/2026 15:45:00. 50 Economy ticket for £19 per person are available. Travel duration is 12h 10m
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Andimar12h 10m021:50AntofagastaCarlos Oviedo Cavada Bus Station10:00La SerenaCentral Coach Station0EconomyA Bus from Andimar goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 10/10/2026 21:50:00 to Central Coach Station, La Serena (Chile) arriving at 11/10/2026 10:00:00. 50 Economy ticket for £19 per person are available. Travel duration is 12h 10m
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Pullman San Andres12h 10m012:00AntofagastaCarlos Oviedo Cavada Bus Station00:10La SerenaCentral Coach Station0Premium EconomyA Bus from Pullman San Andres goes from Carlos Oviedo Cavada Bus Station, Antofagasta (Chile) at 10/10/2026 12:00:00 to Central Coach Station, La Serena (Chile) arriving at 11/10/2026 00:10:00. 50 Premium Economy ticket for £25 per person are available. Travel duration is 12h 10m
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JetSmart12h 14m020:53Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport09:07La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 10/10/2026 20:53:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 11/10/2026 09:07:00. 50 Economy ticket for £54 per person are available. Travel duration is 12h 14m
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JetSmart15h 29m020:53Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport12:22La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from JetSmart goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 10/10/2026 20:53:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 11/10/2026 12:22:00. 50 Economy ticket for £57 per person are available. Travel duration is 15h 29m
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LATAM Brasil16h 19m020:03Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport12:22La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 10/10/2026 20:03:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 11/10/2026 12:22:00. 50 Economy ticket for £74 per person are available. Travel duration is 16h 19m
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LATAM Brasil20h 38m015:44Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport12:22La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from LATAM Brasil goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 10/10/2026 15:44:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 11/10/2026 12:22:00. 50 Economy ticket for £74 per person are available. Travel duration is 20h 38m
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Sky Airline23h 14m013:08Andrés Sabella Gálvez, Antofagasta AirportAndrés Sabella Gálvez, Antofagasta Airport12:22La Florida, La Serena AirportLa Florida, La Serena Airport0EconomyA Flight from Sky Airline goes from Andrés Sabella Gálvez, Antofagasta Airport, Andrés Sabella Gálvez, Antofagasta Airport (Chile) at 10/10/2026 13:08:00 to La Florida, La Serena Airport, La Florida, La Serena Airport (Chile) arriving at 11/10/2026 12:22:00. 50 Economy ticket for £73 per person are available. Travel duration is 23h 14m
Fastest Buses Saturday
Fastest Flights Saturday
Here you will find all operators and timetables for a
Bus from Antofagasta to La Serena
What are the most popular stations in Antofagasta and La Serena?
In Antofagasta, you will usually depart from Carlos Oviedo Cavada Bus Station, Camus Coach Station or Maipú, while in La Serena you will be arriving at Avda. Fco de Aguirre Station, Central Coach Station or El Sto, 1060, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to La Serena from Antofagasta? With 9 connections between 7 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Antofagasta and La Serena, you can pay as low as £19 with a Bus from Andimar.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Sky Airline: you will get to La Serena in just 1h 24m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Antofagasta and La Serena are Andimar, Cormar Bus and Pullman San Andres, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Antofagasta and La Serena is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from La Negra or to La Florida, La Serena Airport, and look at flights from Andrés Sabella Gálvez, Antofagasta Airport, and landing at La Florida, La Serena Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Antofagasta to La Serena?
The most popular companies between Antofagasta and La Serena, are Andimar, Cormar Bus and Pullman San Andres. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Andimar, Cormar Bus, Pullman San Andres and 4 more.
Airlines: JetSmart, LATAM Brasil, Sky Airline and 2 more.
All you need to know when you travel from Antofagasta to La Serena
Check all information on comfort and services on all modes of transports from Antofagasta to La Serena. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Antofagasta to La Serena
How can I reach La Serena from Antofagasta?
Every day, there are on average 9 connections between Flight and Bus, with which you can get to La Serena from Antofagasta.
How far is La Serena from Antofagasta?
The distance between Antofagasta and La Serena is 700.4 km.
What is the most ecofriendly mode of transport between Antofagasta and La Serena?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 19 kgs of CO2, a train 25 kgs, a car 119 kgs, and a flight 172 kgs.
What is the cheapest mode of transport from Antofagasta to La Serena?
You can get to La Serena with just £19 by taking a Bus from Andimar.
What is the fastest way to get from Antofagasta to La Serena?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to La Serena in just 1h 24m with a Flight from Sky Airline.
More routes to Antofagasta and to La Serena
Looking for more options? Here you can see the most popular routes to Antofagasta and to La Serena. Simply click on a connection, and you’ll find all the details about the route!
