What is the best way to travel from San Antonio, TX to Chicago?
Looking for a trip? Check and compare all the available Flights and Buses to Chicago from San Antonio, TX. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 6 available companies to find your perfect trip!
What is the cheapest way to reach Chicago from San Antonio, TX?
You can reach Chicago with just £83 by taking a Bus from Greyhound Lines Mexico, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Greyhound Lines Mexico32h 11m011:59San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 08/11/2026 11:59:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 20:10:00. 50 Economy ticket for £90 per person are available. Travel duration is 32h 11m
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FlixBus32h 35m007:30San Antonio, TXCoach Station16:05ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 08/11/2026 07:30:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 16:05:00. 50 Economy ticket for £90 per person are available. Travel duration is 32h 35m
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FlixBus32h 20m007:45San Antonio, TXPearl District16:05ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 08/11/2026 07:45:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 16:05:00. 50 Economy ticket for £90 per person are available. Travel duration is 32h 20m
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Greyhound Lines Mexico26h 50m001:30San Antonio, TXCoach Station04:20ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 08/11/2026 01:30:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 04:20:00. 50 Economy ticket for £91 per person are available. Travel duration is 26h 50m
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Greyhound Lines Mexico31h 10m004:20San Antonio, TXCoach Station11:30ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 08/11/2026 04:20:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 11:30:00. 50 Economy ticket for £91 per person are available. Travel duration is 31h 10m
Cheapest Buses Sunday
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Greyhound US27h 40m001:30San Antonio, TXCoach Station05:10Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 09/11/2026 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 10/11/2026 05:10:00. 50 Economy ticket for £87 per person are available. Travel duration is 27h 40m
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Greyhound US35h 0m012:35San Antonio, TXCoach Station23:35Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 09/11/2026 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 10/11/2026 23:35:00. 50 Economy ticket for £88 per person are available. Travel duration is 35h 0m
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FlixBus39h 50m007:45San Antonio, TXPearl District23:35Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 09/11/2026 07:45:00 to 95th Red Line Station, Chicago (USA) arriving at 10/11/2026 23:35:00. 50 Economy ticket for £88 per person are available. Travel duration is 39h 50m
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FlixBus35h 55m021:55San Antonio, TXCoach Station09:50Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 09/11/2026 21:55:00 to 95th Red Line Station, Chicago (USA) arriving at 11/11/2026 09:50:00. 50 Economy ticket for £89 per person are available. Travel duration is 35h 55m
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Tornado Bus Company23h 48m011:05San Antonio, TXTornado Bus Company10:52ChicagoCalifornia & 35th Street Coach Stop0EconomyA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 09/11/2026 11:05:00 to California & 35th Street Coach Stop, Chicago (USA) arriving at 10/11/2026 10:52:30. 50 Economy ticket for £191 per person are available. Travel duration is 23h 48m
Cheapest Buses Monday
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Greyhound Lines Mexico38h 5m004:20San Antonio, TXCoach Station18:25Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 11/11/2026 04:20:00 to 95th Red Line Station, Chicago (USA) arriving at 12/11/2026 18:25:00. 50 Economy ticket for £83 per person are available. Travel duration is 38h 5m
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FlixBus32h 10m021:00San Antonio, TXCoach Station05:10Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 11/11/2026 21:00:00 to 95th Red Line Station, Chicago (USA) arriving at 13/11/2026 05:10:00. 50 Economy ticket for £83 per person are available. Travel duration is 32h 10m
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Greyhound US32h 50m001:30San Antonio, TXCoach Station10:20Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 11/11/2026 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 12/11/2026 10:20:00. 50 Economy ticket for £83 per person are available. Travel duration is 32h 50m
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Valley Transit32h 10m021:00San Antonio, TXCoach Station05:10Chicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Coach Station, San Antonio, TX (USA) at 11/11/2026 21:00:00 to 95th Red Line Station, Chicago (USA) arriving at 13/11/2026 05:10:00. 50 Economy ticket for £83 per person are available. Travel duration is 32h 10m
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Tornado Bus Company24h 16m011:05San Antonio, TXTornado Bus Company11:21ChicagoCalifornia & 35th Street Coach Stop0EconomyA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 11/11/2026 11:05:00 to California & 35th Street Coach Stop, Chicago (USA) arriving at 12/11/2026 11:21:00. 50 Economy ticket for £191 per person are available. Travel duration is 24h 16m
Cheapest Buses Wednesday
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Greyhound US27h 40m001:30San Antonio, TXCoach Station05:10Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 12/11/2026 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 13/11/2026 05:10:00. 50 Economy ticket for £83 per person are available. Travel duration is 27h 40m
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Greyhound US35h 0m012:35San Antonio, TXCoach Station23:35Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 12/11/2026 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 13/11/2026 23:35:00. 50 Economy ticket for £83 per person are available. Travel duration is 35h 0m
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Valley Transit32h 10m021:00San Antonio, TXCoach Station05:10Chicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Coach Station, San Antonio, TX (USA) at 12/11/2026 21:00:00 to 95th Red Line Station, Chicago (USA) arriving at 14/11/2026 05:10:00. 50 Economy ticket for £83 per person are available. Travel duration is 32h 10m
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Valley Transit35h 0m021:00San Antonio, TXCoach Station08:00ChicagoCanal & Van Buren0EconomyA Bus from Valley Transit goes from Coach Station, San Antonio, TX (USA) at 12/11/2026 21:00:00 to Canal & Van Buren, Chicago (USA) arriving at 14/11/2026 08:00:00. 50 Economy ticket for £86 per person are available. Travel duration is 35h 0m
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FlixBus34h 55m007:30San Antonio, TXCoach Station18:25Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 12/11/2026 07:30:00 to 95th Red Line Station, Chicago (USA) arriving at 13/11/2026 18:25:00. 50 Economy ticket for £88 per person are available. Travel duration is 34h 55m
Cheapest Buses Thursday
What are the fastest trips from San Antonio, TX to Chicago?
You can get to Chicago from San Antonio, TX in just 23h 48m with a Bus from Tornado Bus Company. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Greyhound Lines Mexico26h 50m001:30San Antonio, TXCoach Station04:20ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 08/11/2026 01:30:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 04:20:00. 50 Economy ticket for £91 per person are available. Travel duration is 26h 50m
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Greyhound Lines Mexico31h 10m004:20San Antonio, TXCoach Station11:30ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 08/11/2026 04:20:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 11:30:00. 50 Economy ticket for £91 per person are available. Travel duration is 31h 10m
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Greyhound Lines Mexico32h 11m011:59San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 08/11/2026 11:59:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 20:10:00. 50 Economy ticket for £90 per person are available. Travel duration is 32h 11m
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FlixBus32h 20m007:45San Antonio, TXPearl District16:05ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 08/11/2026 07:45:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 16:05:00. 50 Economy ticket for £90 per person are available. Travel duration is 32h 20m
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FlixBus32h 35m007:30San Antonio, TXCoach Station16:05ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 08/11/2026 07:30:00 to Downtown Coach Station, Chicago (USA) arriving at 09/11/2026 16:05:00. 50 Economy ticket for £90 per person are available. Travel duration is 32h 35m
Fastest Buses Sunday
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Tornado Bus Company23h 48m011:05San Antonio, TXTornado Bus Company10:52ChicagoCalifornia & 35th Street Coach Stop0EconomyA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 09/11/2026 11:05:00 to California & 35th Street Coach Stop, Chicago (USA) arriving at 10/11/2026 10:52:30. 50 Economy ticket for £191 per person are available. Travel duration is 23h 48m
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Greyhound US27h 40m001:30San Antonio, TXCoach Station05:10Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 09/11/2026 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 10/11/2026 05:10:00. 50 Economy ticket for £87 per person are available. Travel duration is 27h 40m
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Greyhound US35h 0m012:35San Antonio, TXCoach Station23:35Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 09/11/2026 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 10/11/2026 23:35:00. 50 Economy ticket for £88 per person are available. Travel duration is 35h 0m
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FlixBus35h 55m021:55San Antonio, TXCoach Station09:50Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 09/11/2026 21:55:00 to 95th Red Line Station, Chicago (USA) arriving at 11/11/2026 09:50:00. 50 Economy ticket for £89 per person are available. Travel duration is 35h 55m
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FlixBus39h 50m007:45San Antonio, TXPearl District23:35Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 09/11/2026 07:45:00 to 95th Red Line Station, Chicago (USA) arriving at 10/11/2026 23:35:00. 50 Economy ticket for £88 per person are available. Travel duration is 39h 50m
Fastest Buses Monday
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Tornado Bus Company24h 16m011:05San Antonio, TXTornado Bus Company11:21ChicagoCalifornia & 35th Street Coach Stop0EconomyA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 11/11/2026 11:05:00 to California & 35th Street Coach Stop, Chicago (USA) arriving at 12/11/2026 11:21:00. 50 Economy ticket for £191 per person are available. Travel duration is 24h 16m
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FlixBus32h 10m021:00San Antonio, TXCoach Station05:10Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 11/11/2026 21:00:00 to 95th Red Line Station, Chicago (USA) arriving at 13/11/2026 05:10:00. 50 Economy ticket for £83 per person are available. Travel duration is 32h 10m
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Valley Transit32h 10m021:00San Antonio, TXCoach Station05:10Chicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Coach Station, San Antonio, TX (USA) at 11/11/2026 21:00:00 to 95th Red Line Station, Chicago (USA) arriving at 13/11/2026 05:10:00. 50 Economy ticket for £83 per person are available. Travel duration is 32h 10m
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Greyhound US32h 50m001:30San Antonio, TXCoach Station10:20Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 11/11/2026 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 12/11/2026 10:20:00. 50 Economy ticket for £83 per person are available. Travel duration is 32h 50m
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Greyhound Lines Mexico38h 5m004:20San Antonio, TXCoach Station18:25Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 11/11/2026 04:20:00 to 95th Red Line Station, Chicago (USA) arriving at 12/11/2026 18:25:00. 50 Economy ticket for £83 per person are available. Travel duration is 38h 5m
Fastest Buses Wednesday
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Greyhound US27h 40m001:30San Antonio, TXCoach Station05:10Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 12/11/2026 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 13/11/2026 05:10:00. 50 Economy ticket for £83 per person are available. Travel duration is 27h 40m
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Valley Transit32h 10m021:00San Antonio, TXCoach Station05:10Chicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Coach Station, San Antonio, TX (USA) at 12/11/2026 21:00:00 to 95th Red Line Station, Chicago (USA) arriving at 14/11/2026 05:10:00. 50 Economy ticket for £83 per person are available. Travel duration is 32h 10m
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FlixBus34h 55m007:30San Antonio, TXCoach Station18:25Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 12/11/2026 07:30:00 to 95th Red Line Station, Chicago (USA) arriving at 13/11/2026 18:25:00. 50 Economy ticket for £88 per person are available. Travel duration is 34h 55m
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Greyhound US35h 0m012:35San Antonio, TXCoach Station23:35Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 12/11/2026 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 13/11/2026 23:35:00. 50 Economy ticket for £83 per person are available. Travel duration is 35h 0m
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Valley Transit35h 0m021:00San Antonio, TXCoach Station08:00ChicagoCanal & Van Buren0EconomyA Bus from Valley Transit goes from Coach Station, San Antonio, TX (USA) at 12/11/2026 21:00:00 to Canal & Van Buren, Chicago (USA) arriving at 14/11/2026 08:00:00. 50 Economy ticket for £86 per person are available. Travel duration is 35h 0m
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from San Antonio, TX to Chicago
What are the most popular stations in San Antonio, TX and Chicago?
In San Antonio, TX, you will usually depart from Tornado Bus Company, Coach Station or W. Southcross & Buffalo Bus Stop, while in Chicago you will be arriving at California & 35th Street Coach Stop, Downtown Coach Station or 95th Red Line Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Chicago from San Antonio, TX? With 5 connections between 6 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between San Antonio, TX and Chicago, you can pay as low as £83 with a Bus from Greyhound Lines Mexico.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from Tornado Bus Company: you will get to Chicago in just 23h 48m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting San Antonio, TX and Chicago are FlixBus, Greyhound US and Greyhound Lines Mexico, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in San Antonio, TX and Chicago is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Olmos Park, TX or to Cicero, IL, and look at flights from San Antonio Airport, and landing at Chicago Midway Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from San Antonio, TX to Chicago?
The most popular companies between San Antonio, TX and Chicago, are FlixBus, Greyhound US and Greyhound Lines Mexico. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus, Greyhound US, Greyhound Lines Mexico and 2 more.
All you need to know when you travel from San Antonio, TX to Chicago
Check all information on comfort and services on all modes of transports from San Antonio, TX to Chicago. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from San Antonio, TX to Chicago
How can I reach Chicago from San Antonio, TX?
Every day, there are on average 5 connections between Flight and Bus, with which you can get to Chicago from San Antonio, TX.
How far is Chicago from San Antonio, TX?
The distance between San Antonio, TX and Chicago is 1,692.8 km.
What is the most ecofriendly mode of transport between San Antonio, TX and Chicago?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 46 kgs of CO2, a train 59 kgs, a car 288 kgs, and a flight 416 kgs.
What is the cheapest mode of transport from San Antonio, TX to Chicago?
You can get to Chicago with just £83 by taking a Bus from Greyhound Lines Mexico.
What is the fastest way to get from San Antonio, TX to Chicago?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Chicago in just 23h 48m with a Bus from Tornado Bus Company.
More routes to San Antonio, TX and to Chicago
Looking for more options? Here you can see the most popular routes to San Antonio, TX and to Chicago. Simply click on a connection, and you’ll find all the details about the route!
- Trips to San Antonio, TX
- Aguascalientes to San Antonio, TX
- Albuquerque, NM to San Antonio, TX
- Atlanta, GA to San Antonio, TX
- Brownsville, TX to San Antonio, TX
- Chicago to San Antonio, TX
- Durango, DG to San Antonio, TX
- El Paso, TX to San Antonio, TX
- Guadalajara, JC to San Antonio, TX
- Harlingen, TX to San Antonio, TX
- Houston to San Antonio, TX
- Las Vegas to San Antonio, TX
- Los Angeles to San Antonio, TX
- Mexico City to San Antonio, TX
- Monterrey, NL to San Antonio, TX
- Orlando, FL to San Antonio, TX
- Saltillo to San Antonio, TX
- San Luis Potosí to San Antonio, TX
- Santiago de Queretaro to San Antonio, TX
- St. Louis, MO to San Antonio, TX
- Tampico to San Antonio, TX
- Washington, DC to San Antonio, TX
- Zacatecas, ZS to San Antonio, TX
- Trips to Chicago
- Atlanta, GA to Chicago
- Cincinnati to Chicago
- Ciudad Juárez to Chicago
- Cleveland to Chicago
- Columbus, OH to Chicago
- Dallas to Chicago
- Durango, DG to Chicago
- El Paso, TX to Chicago
- Guadalajara, JC to Chicago
- Houston to Chicago
- Los Angeles to Chicago
- McAllen, TX to Chicago
- Memphis to Chicago
- Mexico City to Chicago
- Nashville to Chicago
- New York to Chicago
- Newark to Chicago
- Orlando, FL to Chicago
- Philadelphia, PA to Chicago
- Pittsburgh to Chicago
- San Luis Potosí to Chicago
- Toronto, ON to Chicago
