What is the best way to travel from San Antonio, TX to Chicago?
Looking for a trip? Check and compare all the available Buses and Flights to Chicago from San Antonio, TX. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 7 available companies to find your perfect trip!
What is the cheapest way to reach Chicago from San Antonio, TX?
You can reach Chicago with just £78 by taking a Bus from Greyhound Lines Mexico, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Greyhound US33h 0m012:40San Antonio, TXCoach Station21:40Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 20/07/2025 12:40:00 to 95th Red Line Station, Chicago (USA) arriving at 21/07/2025 21:40:00. 50 Economy ticket for £95 per person are available. Travel duration is 33h 0m
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FlixBus32h 20m021:00San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 20/07/2025 21:00:00 to 95th Red Line Station, Chicago (USA) arriving at 22/07/2025 05:20:00. 50 Economy ticket for £98 per person are available. Travel duration is 32h 20m
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Greyhound Lines Mexico33h 55m006:05San Antonio, TXCoach Station16:00Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 20/07/2025 06:05:00 to 95th Red Line Station, Chicago (USA) arriving at 21/07/2025 16:00:00. 50 Economy ticket for £101 per person are available. Travel duration is 33h 55m
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FlixBus51h 20m007:45San Antonio, TXPearl District11:05Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 20/07/2025 07:45:00 to 95th Red Line Station, Chicago (USA) arriving at 22/07/2025 11:05:00. 50 Economy ticket for £105 per person are available. Travel duration is 51h 20m
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Greyhound Lines Mexico27h 50m001:30San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 20/07/2025 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 21/07/2025 05:20:00. 50 Economy ticket for £120 per person are available. Travel duration is 27h 50m
Cheapest Buses Sunday
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Greyhound Lines Mexico34h 5m019:15San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 21/07/2025 19:15:00 to 95th Red Line Station, Chicago (USA) arriving at 23/07/2025 05:20:00. 50 Economy ticket for £123 per person are available. Travel duration is 34h 5m
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Greyhound Lines Mexico33h 55m006:05San Antonio, TXCoach Station16:00Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 21/07/2025 06:05:00 to 95th Red Line Station, Chicago (USA) arriving at 22/07/2025 16:00:00. 50 Economy ticket for £124 per person are available. Travel duration is 33h 55m
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Greyhound US33h 0m012:40San Antonio, TXCoach Station21:40Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 21/07/2025 12:40:00 to 95th Red Line Station, Chicago (USA) arriving at 22/07/2025 21:40:00. 50 Economy ticket for £124 per person are available. Travel duration is 33h 0m
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Greyhound US31h 30m012:40San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 21/07/2025 12:40:00 to Downtown Coach Station, Chicago (USA) arriving at 22/07/2025 20:10:00. 50 Economy ticket for £126 per person are available. Travel duration is 31h 30m
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FlixBus51h 20m007:45San Antonio, TXPearl District11:05Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 21/07/2025 07:45:00 to 95th Red Line Station, Chicago (USA) arriving at 23/07/2025 11:05:00. 50 Economy ticket for £126 per person are available. Travel duration is 51h 20m
Cheapest Buses Monday
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Greyhound Lines Mexico34h 5m019:15San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 22/07/2025 19:15:00 to 95th Red Line Station, Chicago (USA) arriving at 24/07/2025 05:20:00. 50 Economy ticket for £92 per person are available. Travel duration is 34h 5m
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Greyhound US33h 0m012:40San Antonio, TXCoach Station21:40Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 22/07/2025 12:40:00 to 95th Red Line Station, Chicago (USA) arriving at 23/07/2025 21:40:00. 50 Economy ticket for £102 per person are available. Travel duration is 33h 0m
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Tornado Bus Company23h 35m011:05San Antonio, TXTornado Bus Company10:40ChicagoCalifornia & 35th Street Coach Stop0BasicA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 22/07/2025 11:05:00 to California & 35th Street Coach Stop, Chicago (USA) arriving at 23/07/2025 10:40:30. 50 Basic ticket for £183 per person are available. Travel duration is 23h 35m
Cheapest Buses Tuesday
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Greyhound Lines Mexico33h 10m006:05San Antonio, TXCoach Station15:15ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 23/07/2025 06:05:00 to Downtown Coach Station, Chicago (USA) arriving at 24/07/2025 15:15:00. 50 Economy ticket for £123 per person are available. Travel duration is 33h 10m
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FlixBus30h 40m021:00San Antonio, TXCoach Station03:40ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 23/07/2025 21:00:00 to Downtown Coach Station, Chicago (USA) arriving at 25/07/2025 03:40:00. 50 Economy ticket for £123 per person are available. Travel duration is 30h 40m
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Greyhound Lines Mexico26h 10m001:30San Antonio, TXCoach Station03:40ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 23/07/2025 01:30:00 to Downtown Coach Station, Chicago (USA) arriving at 24/07/2025 03:40:00. 50 Economy ticket for £124 per person are available. Travel duration is 26h 10m
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Greyhound US31h 30m012:40San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 23/07/2025 12:40:00 to Downtown Coach Station, Chicago (USA) arriving at 24/07/2025 20:10:00. 50 Economy ticket for £124 per person are available. Travel duration is 31h 30m
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FlixBus51h 20m007:45San Antonio, TXPearl District11:05Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 23/07/2025 07:45:00 to 95th Red Line Station, Chicago (USA) arriving at 25/07/2025 11:05:00. 50 Economy ticket for £130 per person are available. Travel duration is 51h 20m
Cheapest Buses Wednesday
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Greyhound Lines Mexico33h 55m006:05San Antonio, TXCoach Station16:00Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 24/07/2025 06:05:00 to 95th Red Line Station, Chicago (USA) arriving at 25/07/2025 16:00:00. 50 Economy ticket for £78 per person are available. Travel duration is 33h 55m
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Greyhound US33h 0m012:40San Antonio, TXCoach Station21:40Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 24/07/2025 12:40:00 to 95th Red Line Station, Chicago (USA) arriving at 25/07/2025 21:40:00. 50 Economy ticket for £79 per person are available. Travel duration is 33h 0m
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FlixBus51h 20m007:45San Antonio, TXPearl District11:05Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 24/07/2025 07:45:00 to 95th Red Line Station, Chicago (USA) arriving at 26/07/2025 11:05:00. 50 Economy ticket for £80 per person are available. Travel duration is 51h 20m
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Valley Transit32h 20m021:00San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Coach Station, San Antonio, TX (USA) at 24/07/2025 21:00:00 to 95th Red Line Station, Chicago (USA) arriving at 26/07/2025 05:20:00. 50 Economy ticket for £85 per person are available. Travel duration is 32h 20m
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Tornado Bus Company23h 35m011:05San Antonio, TXTornado Bus Company10:40ChicagoCalifornia & 35th Street Coach Stop0BasicA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 24/07/2025 11:05:00 to California & 35th Street Coach Stop, Chicago (USA) arriving at 25/07/2025 10:40:30. 50 Basic ticket for £183 per person are available. Travel duration is 23h 35m
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Frontier Airlines27h 56m020:14San Antonio AirportSan Antonio Airport00:10Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/07/2025 20:14:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/07/2025 00:10:00. 50 Economy ticket for £112 per person are available. Travel duration is 27h 56m
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Spirit Airlines10h 23m012:01San Antonio AirportSan Antonio Airport22:24Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/07/2025 12:01:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 24/07/2025 22:24:00. 50 Economy ticket for £120 per person are available. Travel duration is 10h 23m
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Frontier Airlines15h 27m020:14San Antonio AirportSan Antonio Airport11:41Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/07/2025 20:14:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 25/07/2025 11:41:00. 50 Economy ticket for £132 per person are available. Travel duration is 15h 27m
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Spirit Airlines15h 14m014:11San Antonio AirportSan Antonio Airport05:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/07/2025 14:11:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/07/2025 05:25:00. 50 Economy ticket for £132 per person are available. Travel duration is 15h 14m
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Spirit Airlines12h 57m007:25San Antonio AirportSan Antonio Airport20:22Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/07/2025 07:25:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 24/07/2025 20:22:00. 50 Economy ticket for £193 per person are available. Travel duration is 12h 57m
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United Airlines2h 59m006:45San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/07/2025 06:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/07/2025 09:44:00. 50 Economy ticket for £213 per person are available. Travel duration is 2h 59m
Cheapest Buses Thursday
Cheapest Flights Thursday
What are the fastest trips from San Antonio, TX to Chicago?
You can get to Chicago from San Antonio, TX in just 2h 59m with a Flight from United Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Greyhound Lines Mexico27h 50m001:30San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 20/07/2025 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 21/07/2025 05:20:00. 50 Economy ticket for £120 per person are available. Travel duration is 27h 50m
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FlixBus32h 20m021:00San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 20/07/2025 21:00:00 to 95th Red Line Station, Chicago (USA) arriving at 22/07/2025 05:20:00. 50 Economy ticket for £98 per person are available. Travel duration is 32h 20m
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Greyhound US33h 0m012:40San Antonio, TXCoach Station21:40Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 20/07/2025 12:40:00 to 95th Red Line Station, Chicago (USA) arriving at 21/07/2025 21:40:00. 50 Economy ticket for £95 per person are available. Travel duration is 33h 0m
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Greyhound Lines Mexico33h 55m006:05San Antonio, TXCoach Station16:00Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 20/07/2025 06:05:00 to 95th Red Line Station, Chicago (USA) arriving at 21/07/2025 16:00:00. 50 Economy ticket for £101 per person are available. Travel duration is 33h 55m
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FlixBus51h 20m007:45San Antonio, TXPearl District11:05Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 20/07/2025 07:45:00 to 95th Red Line Station, Chicago (USA) arriving at 22/07/2025 11:05:00. 50 Economy ticket for £105 per person are available. Travel duration is 51h 20m
Fastest Buses Sunday
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Greyhound US31h 30m012:40San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 21/07/2025 12:40:00 to Downtown Coach Station, Chicago (USA) arriving at 22/07/2025 20:10:00. 50 Economy ticket for £126 per person are available. Travel duration is 31h 30m
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Greyhound US33h 0m012:40San Antonio, TXCoach Station21:40Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 21/07/2025 12:40:00 to 95th Red Line Station, Chicago (USA) arriving at 22/07/2025 21:40:00. 50 Economy ticket for £124 per person are available. Travel duration is 33h 0m
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Greyhound Lines Mexico33h 55m006:05San Antonio, TXCoach Station16:00Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 21/07/2025 06:05:00 to 95th Red Line Station, Chicago (USA) arriving at 22/07/2025 16:00:00. 50 Economy ticket for £124 per person are available. Travel duration is 33h 55m
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Greyhound Lines Mexico34h 5m019:15San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 21/07/2025 19:15:00 to 95th Red Line Station, Chicago (USA) arriving at 23/07/2025 05:20:00. 50 Economy ticket for £123 per person are available. Travel duration is 34h 5m
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FlixBus51h 20m007:45San Antonio, TXPearl District11:05Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 21/07/2025 07:45:00 to 95th Red Line Station, Chicago (USA) arriving at 23/07/2025 11:05:00. 50 Economy ticket for £126 per person are available. Travel duration is 51h 20m
Fastest Buses Monday
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Tornado Bus Company23h 35m011:05San Antonio, TXTornado Bus Company10:40ChicagoCalifornia & 35th Street Coach Stop0BasicA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 22/07/2025 11:05:00 to California & 35th Street Coach Stop, Chicago (USA) arriving at 23/07/2025 10:40:30. 50 Basic ticket for £183 per person are available. Travel duration is 23h 35m
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Greyhound US33h 0m012:40San Antonio, TXCoach Station21:40Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 22/07/2025 12:40:00 to 95th Red Line Station, Chicago (USA) arriving at 23/07/2025 21:40:00. 50 Economy ticket for £102 per person are available. Travel duration is 33h 0m
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Greyhound Lines Mexico34h 5m019:15San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 22/07/2025 19:15:00 to 95th Red Line Station, Chicago (USA) arriving at 24/07/2025 05:20:00. 50 Economy ticket for £92 per person are available. Travel duration is 34h 5m
Fastest Buses Tuesday
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Greyhound Lines Mexico26h 10m001:30San Antonio, TXCoach Station03:40ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 23/07/2025 01:30:00 to Downtown Coach Station, Chicago (USA) arriving at 24/07/2025 03:40:00. 50 Economy ticket for £124 per person are available. Travel duration is 26h 10m
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FlixBus30h 40m021:00San Antonio, TXCoach Station03:40ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 23/07/2025 21:00:00 to Downtown Coach Station, Chicago (USA) arriving at 25/07/2025 03:40:00. 50 Economy ticket for £123 per person are available. Travel duration is 30h 40m
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Greyhound US31h 30m012:40San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 23/07/2025 12:40:00 to Downtown Coach Station, Chicago (USA) arriving at 24/07/2025 20:10:00. 50 Economy ticket for £124 per person are available. Travel duration is 31h 30m
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Greyhound Lines Mexico33h 10m006:05San Antonio, TXCoach Station15:15ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 23/07/2025 06:05:00 to Downtown Coach Station, Chicago (USA) arriving at 24/07/2025 15:15:00. 50 Economy ticket for £123 per person are available. Travel duration is 33h 10m
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FlixBus51h 20m007:45San Antonio, TXPearl District11:05Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 23/07/2025 07:45:00 to 95th Red Line Station, Chicago (USA) arriving at 25/07/2025 11:05:00. 50 Economy ticket for £130 per person are available. Travel duration is 51h 20m
Fastest Buses Wednesday
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United Airlines2h 59m006:45San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/07/2025 06:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/07/2025 09:44:00. 50 Economy ticket for £213 per person are available. Travel duration is 2h 59m
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Skyscanner3h 5m017:20San Antonio AirportSan Antonio Airport20:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Skyscanner goes from San Antonio Airport, San Antonio Airport (USA) at 24/07/2025 17:20:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/07/2025 20:25:00. 50 Economy ticket for £213 per person are available. Travel duration is 3h 5m
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Spirit Airlines10h 23m012:01San Antonio AirportSan Antonio Airport22:24Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/07/2025 12:01:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 24/07/2025 22:24:00. 50 Economy ticket for £120 per person are available. Travel duration is 10h 23m
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Spirit Airlines12h 57m007:25San Antonio AirportSan Antonio Airport20:22Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/07/2025 07:25:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 24/07/2025 20:22:00. 50 Economy ticket for £193 per person are available. Travel duration is 12h 57m
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Spirit Airlines15h 14m014:11San Antonio AirportSan Antonio Airport05:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/07/2025 14:11:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/07/2025 05:25:00. 50 Economy ticket for £132 per person are available. Travel duration is 15h 14m
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Frontier Airlines15h 27m020:14San Antonio AirportSan Antonio Airport11:41Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/07/2025 20:14:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 25/07/2025 11:41:00. 50 Economy ticket for £132 per person are available. Travel duration is 15h 27m
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Tornado Bus Company23h 35m011:05San Antonio, TXTornado Bus Company10:40ChicagoCalifornia & 35th Street Coach Stop0BasicA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 24/07/2025 11:05:00 to California & 35th Street Coach Stop, Chicago (USA) arriving at 25/07/2025 10:40:30. 50 Basic ticket for £183 per person are available. Travel duration is 23h 35m
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Valley Transit32h 20m021:00San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Coach Station, San Antonio, TX (USA) at 24/07/2025 21:00:00 to 95th Red Line Station, Chicago (USA) arriving at 26/07/2025 05:20:00. 50 Economy ticket for £85 per person are available. Travel duration is 32h 20m
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Greyhound US33h 0m012:40San Antonio, TXCoach Station21:40Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 24/07/2025 12:40:00 to 95th Red Line Station, Chicago (USA) arriving at 25/07/2025 21:40:00. 50 Economy ticket for £79 per person are available. Travel duration is 33h 0m
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Greyhound Lines Mexico33h 55m006:05San Antonio, TXCoach Station16:00Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 24/07/2025 06:05:00 to 95th Red Line Station, Chicago (USA) arriving at 25/07/2025 16:00:00. 50 Economy ticket for £78 per person are available. Travel duration is 33h 55m
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FlixBus51h 20m007:45San Antonio, TXPearl District11:05Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 24/07/2025 07:45:00 to 95th Red Line Station, Chicago (USA) arriving at 26/07/2025 11:05:00. 50 Economy ticket for £80 per person are available. Travel duration is 51h 20m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from San Antonio, TX to Chicago
What are the most popular stations in San Antonio, TX and Chicago?
In San Antonio, TX, you will usually depart from Coach Station, W. Southcross & Buffalo Bus Stop or La Cantera, while in Chicago you will be arriving at Union Station, 95th Red Line Station or California & 35th Street Coach Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Chicago from San Antonio, TX? With 6 connections between 7 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between San Antonio, TX and Chicago, you can pay as low as £78 with a Bus from Greyhound Lines Mexico.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Chicago in just 2h 59m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting San Antonio, TX and Chicago are Greyhound Lines Mexico, Greyhound US and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in San Antonio, TX and Chicago is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Olmos Park, TX or to Cicero, IL, and look at flights from San Antonio Airport, and landing at Chicago Midway Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from San Antonio, TX to Chicago?
The most popular companies between San Antonio, TX and Chicago, are Greyhound Lines Mexico, Greyhound US and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound Lines Mexico, Greyhound US, FlixBus and 2 more.
Airlines: Spirit Airlines, Frontier Airlines, United Airlines and 2 more.
All you need to know when you travel from San Antonio, TX to Chicago
Check all information on comfort and services on all modes of transports from San Antonio, TX to Chicago. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from San Antonio, TX to Chicago
How can I reach Chicago from San Antonio, TX?
Every day, there are on average 6 connections between Bus and Flight, with which you can get to Chicago from San Antonio, TX.
How far is Chicago from San Antonio, TX?
The distance between San Antonio, TX and Chicago is 1,692.8 km.
What is the most ecofriendly mode of transport between San Antonio, TX and Chicago?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 46 kgs of CO2, a train 59 kgs, a car 288 kgs, and a flight 416 kgs.
What is the cheapest mode of transport from San Antonio, TX to Chicago?
You can get to Chicago with just £78 by taking a Bus from Greyhound Lines Mexico.
What is the fastest way to get from San Antonio, TX to Chicago?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Chicago in just 2h 59m with a Flight from United Airlines.
More routes to San Antonio, TX and to Chicago
Looking for more options? Here you can see the most popular routes to San Antonio, TX and to Chicago. Simply click on a connection, and you’ll find all the details about the route!
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- Mexico City to San Antonio, TX
- Monterrey, NL to San Antonio, TX
- Orlando, FL to San Antonio, TX
- Phoenix, AZ to San Antonio, TX
- Reynosa to San Antonio, TX
- San Diego to San Antonio, TX
- San Luis Potosí to San Antonio, TX
- Santiago de Queretaro to San Antonio, TX
- Torreón, CO to San Antonio, TX
- Trips to Chicago
- Atlanta, GA to Chicago
- Buffalo, NY to Chicago
- Ciudad Juárez to Chicago
- Dallas to Chicago
- Durango, DG to Chicago
- El Paso, TX to Chicago
- Houston to Chicago
- Little Rock, AR to Chicago
- Los Angeles to Chicago
- Matamoros to Chicago
- McAllen, TX to Chicago
- Mexico City to Chicago
- Monterrey, NL to Chicago
- New York to Chicago
- Niagara Falls, ON to Chicago
- San Diego to Chicago
- San Luis Potosí to Chicago
- St. Louis, MO to Chicago
- Toronto, ON to Chicago
- Washington, DC to Chicago