What is the best way to travel from San Antonio, TX to Chicago?
Looking for a trip? Check and compare all the available Buses and Flights to Chicago from San Antonio, TX. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach Chicago from San Antonio, TX?
You can reach Chicago with just £105 by taking a Bus from Greyhound US, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Greyhound US35h 0m012:35San Antonio, TXCoach Station23:35Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 20/01/2026 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 21/01/2026 23:35:00. 50 Economy ticket for £105 per person are available. Travel duration is 35h 0m
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Greyhound Lines Mexico38h 35m019:15San Antonio, TXCoach Station09:50Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 20/01/2026 19:15:00 to 95th Red Line Station, Chicago (USA) arriving at 22/01/2026 09:50:00. 50 Economy ticket for £105 per person are available. Travel duration is 38h 35m
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Greyhound Lines Mexico32h 55m019:15San Antonio, TXCoach Station04:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 20/01/2026 19:15:00 to Downtown Coach Station, Chicago (USA) arriving at 22/01/2026 04:10:00. 50 Economy ticket for £120 per person are available. Travel duration is 32h 55m
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Greyhound Lines Mexico36h 45m019:15San Antonio, TXCoach Station08:00ChicagoUnion Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 20/01/2026 19:15:00 to Union Station, Chicago (USA) arriving at 22/01/2026 08:00:00. 50 Economy ticket for £121 per person are available. Travel duration is 36h 45m
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Greyhound US31h 35m012:35San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 20/01/2026 12:35:00 to Downtown Coach Station, Chicago (USA) arriving at 21/01/2026 20:10:00. 50 Economy ticket for £122 per person are available. Travel duration is 31h 35m
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Volaris27h 48m019:37San Antonio AirportSan Antonio Airport23:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 20/01/2026 19:37:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/01/2026 23:25:00. 50 Economy ticket for £209 per person are available. Travel duration is 27h 48m
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Viva Aerobus11h 51m016:45San Antonio AirportSan Antonio Airport04:36Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 20/01/2026 16:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/01/2026 04:36:00. 50 Economy ticket for £218 per person are available. Travel duration is 11h 51m
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Aeroméxico16h 16m012:20San Antonio AirportSan Antonio Airport04:36Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Aeroméxico goes from San Antonio Airport, San Antonio Airport (USA) at 20/01/2026 12:20:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/01/2026 04:36:00. 50 Economy ticket for £254 per person are available. Travel duration is 16h 16m
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Volaris17h 3m019:37San Antonio AirportSan Antonio Airport12:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 20/01/2026 19:37:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/01/2026 12:40:00. 50 Economy ticket for £271 per person are available. Travel duration is 17h 3m
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United Airlines2h 51m009:00San Antonio AirportSan Antonio Airport11:51Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 20/01/2026 09:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 20/01/2026 11:51:00. 50 Economy ticket for £288 per person are available. Travel duration is 2h 51m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Greyhound US31h 35m012:35San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 22/01/2026 12:35:00 to Downtown Coach Station, Chicago (USA) arriving at 23/01/2026 20:10:00. 50 Economy ticket for £122 per person are available. Travel duration is 31h 35m
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Greyhound Lines Mexico26h 40m001:30San Antonio, TXCoach Station04:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 22/01/2026 01:30:00 to Downtown Coach Station, Chicago (USA) arriving at 23/01/2026 04:10:00. 50 Economy ticket for £123 per person are available. Travel duration is 26h 40m
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FlixBus30h 55m021:15San Antonio, TXCoach Station04:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 22/01/2026 21:15:00 to Downtown Coach Station, Chicago (USA) arriving at 24/01/2026 04:10:00. 50 Economy ticket for £123 per person are available. Travel duration is 30h 55m
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FlixBus33h 0m007:30San Antonio, TXCoach Station16:30ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 22/01/2026 07:30:00 to Downtown Coach Station, Chicago (USA) arriving at 23/01/2026 16:30:00. 50 Economy ticket for £124 per person are available. Travel duration is 33h 0m
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Greyhound Lines Mexico30h 30m001:30San Antonio, TXCoach Station08:00ChicagoUnion Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 22/01/2026 01:30:00 to Union Station, Chicago (USA) arriving at 23/01/2026 08:00:00. 50 Economy ticket for £125 per person are available. Travel duration is 30h 30m
Cheapest Buses Thursday
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Spirit Airlines13h 11m006:30San Antonio AirportSan Antonio Airport19:41Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/01/2026 06:30:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/01/2026 19:41:00. 50 Economy ticket for £163 per person are available. Travel duration is 13h 11m
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Spirit Airlines9h 3m010:35San Antonio AirportSan Antonio Airport19:38Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/01/2026 10:35:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/01/2026 19:38:00. 50 Economy ticket for £199 per person are available. Travel duration is 9h 3m
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Frontier Airlines14h 30m018:13San Antonio AirportSan Antonio Airport08:43Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/01/2026 18:13:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 24/01/2026 08:43:00. 50 Economy ticket for £202 per person are available. Travel duration is 14h 30m
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Frontier Airlines28h 31m018:13San Antonio AirportSan Antonio Airport22:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/01/2026 18:13:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/01/2026 22:44:00. 50 Economy ticket for £202 per person are available. Travel duration is 28h 31m
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Spirit Airlines13h 22m006:30San Antonio AirportSan Antonio Airport19:52Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/01/2026 06:30:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 23/01/2026 19:52:00. 50 Economy ticket for £210 per person are available. Travel duration is 13h 22m
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United Airlines2h 51m007:00San Antonio AirportSan Antonio Airport09:51Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/01/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/01/2026 09:51:00. 50 Economy ticket for £308 per person are available. Travel duration is 2h 51m
Cheapest Flights Friday
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Greyhound Lines Mexico27h 50m001:30San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 24/01/2026 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 25/01/2026 05:20:00. 50 Economy ticket for £118 per person are available. Travel duration is 27h 50m
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FlixBus32h 25m007:30San Antonio, TXCoach Station15:55Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 24/01/2026 07:30:00 to 95th Red Line Station, Chicago (USA) arriving at 25/01/2026 15:55:00. 50 Economy ticket for £118 per person are available. Travel duration is 32h 25m
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FlixBus32h 5m021:15San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 24/01/2026 21:15:00 to 95th Red Line Station, Chicago (USA) arriving at 26/01/2026 05:20:00. 50 Economy ticket for £118 per person are available. Travel duration is 32h 5m
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Greyhound US35h 0m012:35San Antonio, TXCoach Station23:35Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 24/01/2026 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 25/01/2026 23:35:00. 50 Economy ticket for £118 per person are available. Travel duration is 35h 0m
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Greyhound US31h 35m012:35San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 24/01/2026 12:35:00 to Downtown Coach Station, Chicago (USA) arriving at 25/01/2026 20:10:00. 50 Economy ticket for £129 per person are available. Travel duration is 31h 35m
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Spirit Airlines10h 28m010:35San Antonio AirportSan Antonio Airport21:03Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/01/2026 10:35:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/01/2026 21:03:00. 50 Economy ticket for £126 per person are available. Travel duration is 10h 28m
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Viva Aerobus11h 51m016:45San Antonio AirportSan Antonio Airport04:36Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 24/01/2026 16:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/01/2026 04:36:00. 50 Economy ticket for £210 per person are available. Travel duration is 11h 51m
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Volaris27h 48m019:37San Antonio AirportSan Antonio Airport23:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 24/01/2026 19:37:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/01/2026 23:25:00. 50 Economy ticket for £240 per person are available. Travel duration is 27h 48m
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Aeroméxico11h 5m012:20San Antonio AirportSan Antonio Airport23:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Aeroméxico goes from San Antonio Airport, San Antonio Airport (USA) at 24/01/2026 12:20:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/01/2026 23:25:00. 50 Economy ticket for £265 per person are available. Travel duration is 11h 5m
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United Airlines2h 52m007:00San Antonio AirportSan Antonio Airport09:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/01/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/01/2026 09:52:00. 50 Economy ticket for £292 per person are available. Travel duration is 2h 52m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Spirit Airlines9h 3m010:35San Antonio AirportSan Antonio Airport19:38Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/01/2026 10:35:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/01/2026 19:38:00. 50 Economy ticket for £157 per person are available. Travel duration is 9h 3m
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Frontier Airlines17h 52m018:13San Antonio AirportSan Antonio Airport12:05Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/01/2026 18:13:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 27/01/2026 12:05:00. 50 Economy ticket for £187 per person are available. Travel duration is 17h 52m
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Frontier Airlines19h 45m018:13San Antonio AirportSan Antonio Airport13:58Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/01/2026 18:13:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 27/01/2026 13:58:00. 50 Economy ticket for £187 per person are available. Travel duration is 19h 45m
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Volaris27h 48m019:37San Antonio AirportSan Antonio Airport23:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 26/01/2026 19:37:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 27/01/2026 23:25:00. 50 Economy ticket for £202 per person are available. Travel duration is 27h 48m
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Viva Aerobus11h 51m016:45San Antonio AirportSan Antonio Airport04:36Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 26/01/2026 16:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 27/01/2026 04:36:00. 50 Economy ticket for £212 per person are available. Travel duration is 11h 51m
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Spirit Airlines13h 28m006:30San Antonio AirportSan Antonio Airport19:58Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/01/2026 06:30:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 26/01/2026 19:58:00. 50 Economy ticket for £236 per person are available. Travel duration is 13h 28m
Cheapest Flights Monday
What are the fastest trips from San Antonio, TX to Chicago?
You can get to Chicago from San Antonio, TX in just 2h 51m with a Flight from United Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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United Airlines2h 51m009:00San Antonio AirportSan Antonio Airport11:51Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 20/01/2026 09:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 20/01/2026 11:51:00. 50 Economy ticket for £288 per person are available. Travel duration is 2h 51m
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Viva Aerobus11h 51m016:45San Antonio AirportSan Antonio Airport04:36Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 20/01/2026 16:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/01/2026 04:36:00. 50 Economy ticket for £218 per person are available. Travel duration is 11h 51m
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Aeroméxico16h 16m012:20San Antonio AirportSan Antonio Airport04:36Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Aeroméxico goes from San Antonio Airport, San Antonio Airport (USA) at 20/01/2026 12:20:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/01/2026 04:36:00. 50 Economy ticket for £254 per person are available. Travel duration is 16h 16m
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Volaris17h 3m019:37San Antonio AirportSan Antonio Airport12:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 20/01/2026 19:37:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/01/2026 12:40:00. 50 Economy ticket for £271 per person are available. Travel duration is 17h 3m
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Volaris27h 48m019:37San Antonio AirportSan Antonio Airport23:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 20/01/2026 19:37:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/01/2026 23:25:00. 50 Economy ticket for £209 per person are available. Travel duration is 27h 48m
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Greyhound US31h 35m012:35San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 20/01/2026 12:35:00 to Downtown Coach Station, Chicago (USA) arriving at 21/01/2026 20:10:00. 50 Economy ticket for £122 per person are available. Travel duration is 31h 35m
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Greyhound Lines Mexico32h 55m019:15San Antonio, TXCoach Station04:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 20/01/2026 19:15:00 to Downtown Coach Station, Chicago (USA) arriving at 22/01/2026 04:10:00. 50 Economy ticket for £120 per person are available. Travel duration is 32h 55m
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Greyhound US35h 0m012:35San Antonio, TXCoach Station23:35Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 20/01/2026 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 21/01/2026 23:35:00. 50 Economy ticket for £105 per person are available. Travel duration is 35h 0m
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Greyhound Lines Mexico36h 45m019:15San Antonio, TXCoach Station08:00ChicagoUnion Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 20/01/2026 19:15:00 to Union Station, Chicago (USA) arriving at 22/01/2026 08:00:00. 50 Economy ticket for £121 per person are available. Travel duration is 36h 45m
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Greyhound Lines Mexico38h 35m019:15San Antonio, TXCoach Station09:50Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 20/01/2026 19:15:00 to 95th Red Line Station, Chicago (USA) arriving at 22/01/2026 09:50:00. 50 Economy ticket for £105 per person are available. Travel duration is 38h 35m
Fastest Flights Tuesday
Fastest Buses Tuesday
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Greyhound Lines Mexico26h 40m001:30San Antonio, TXCoach Station04:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 22/01/2026 01:30:00 to Downtown Coach Station, Chicago (USA) arriving at 23/01/2026 04:10:00. 50 Economy ticket for £123 per person are available. Travel duration is 26h 40m
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Greyhound Lines Mexico30h 30m001:30San Antonio, TXCoach Station08:00ChicagoUnion Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 22/01/2026 01:30:00 to Union Station, Chicago (USA) arriving at 23/01/2026 08:00:00. 50 Economy ticket for £125 per person are available. Travel duration is 30h 30m
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FlixBus30h 55m021:15San Antonio, TXCoach Station04:10ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 22/01/2026 21:15:00 to Downtown Coach Station, Chicago (USA) arriving at 24/01/2026 04:10:00. 50 Economy ticket for £123 per person are available. Travel duration is 30h 55m
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Greyhound US31h 35m012:35San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 22/01/2026 12:35:00 to Downtown Coach Station, Chicago (USA) arriving at 23/01/2026 20:10:00. 50 Economy ticket for £122 per person are available. Travel duration is 31h 35m
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FlixBus33h 0m007:30San Antonio, TXCoach Station16:30ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 22/01/2026 07:30:00 to Downtown Coach Station, Chicago (USA) arriving at 23/01/2026 16:30:00. 50 Economy ticket for £124 per person are available. Travel duration is 33h 0m
Fastest Buses Thursday
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United Airlines2h 51m007:00San Antonio AirportSan Antonio Airport09:51Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/01/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/01/2026 09:51:00. 50 Economy ticket for £308 per person are available. Travel duration is 2h 51m
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United Airlines4h 42m005:25San Antonio AirportSan Antonio Airport10:07Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/01/2026 05:25:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/01/2026 10:07:00. 50 Economy ticket for £316 per person are available. Travel duration is 4h 42m
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Spirit Airlines9h 3m010:35San Antonio AirportSan Antonio Airport19:38Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/01/2026 10:35:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/01/2026 19:38:00. 50 Economy ticket for £199 per person are available. Travel duration is 9h 3m
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Spirit Airlines13h 11m006:30San Antonio AirportSan Antonio Airport19:41Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/01/2026 06:30:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/01/2026 19:41:00. 50 Economy ticket for £163 per person are available. Travel duration is 13h 11m
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Spirit Airlines13h 22m006:30San Antonio AirportSan Antonio Airport19:52Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/01/2026 06:30:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 23/01/2026 19:52:00. 50 Economy ticket for £210 per person are available. Travel duration is 13h 22m
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Frontier Airlines14h 30m018:13San Antonio AirportSan Antonio Airport08:43Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/01/2026 18:13:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 24/01/2026 08:43:00. 50 Economy ticket for £202 per person are available. Travel duration is 14h 30m
Fastest Flights Friday
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United Airlines2h 52m007:00San Antonio AirportSan Antonio Airport09:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/01/2026 07:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/01/2026 09:52:00. 50 Economy ticket for £292 per person are available. Travel duration is 2h 52m
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Spirit Airlines10h 28m010:35San Antonio AirportSan Antonio Airport21:03Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/01/2026 10:35:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/01/2026 21:03:00. 50 Economy ticket for £126 per person are available. Travel duration is 10h 28m
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Aeroméxico11h 5m012:20San Antonio AirportSan Antonio Airport23:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Aeroméxico goes from San Antonio Airport, San Antonio Airport (USA) at 24/01/2026 12:20:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/01/2026 23:25:00. 50 Economy ticket for £265 per person are available. Travel duration is 11h 5m
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Viva Aerobus11h 51m016:45San Antonio AirportSan Antonio Airport04:36Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 24/01/2026 16:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/01/2026 04:36:00. 50 Economy ticket for £210 per person are available. Travel duration is 11h 51m
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Volaris27h 48m019:37San Antonio AirportSan Antonio Airport23:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 24/01/2026 19:37:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/01/2026 23:25:00. 50 Economy ticket for £240 per person are available. Travel duration is 27h 48m
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Greyhound Lines Mexico27h 50m001:30San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 24/01/2026 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 25/01/2026 05:20:00. 50 Economy ticket for £118 per person are available. Travel duration is 27h 50m
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Greyhound US31h 35m012:35San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 24/01/2026 12:35:00 to Downtown Coach Station, Chicago (USA) arriving at 25/01/2026 20:10:00. 50 Economy ticket for £129 per person are available. Travel duration is 31h 35m
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FlixBus32h 5m021:15San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 24/01/2026 21:15:00 to 95th Red Line Station, Chicago (USA) arriving at 26/01/2026 05:20:00. 50 Economy ticket for £118 per person are available. Travel duration is 32h 5m
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FlixBus32h 25m007:30San Antonio, TXCoach Station15:55Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 24/01/2026 07:30:00 to 95th Red Line Station, Chicago (USA) arriving at 25/01/2026 15:55:00. 50 Economy ticket for £118 per person are available. Travel duration is 32h 25m
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Greyhound US35h 0m012:35San Antonio, TXCoach Station23:35Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 24/01/2026 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 25/01/2026 23:35:00. 50 Economy ticket for £118 per person are available. Travel duration is 35h 0m
Fastest Flights Saturday
Fastest Buses Saturday
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Spirit Airlines9h 3m010:35San Antonio AirportSan Antonio Airport19:38Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/01/2026 10:35:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/01/2026 19:38:00. 50 Economy ticket for £157 per person are available. Travel duration is 9h 3m
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Viva Aerobus11h 51m016:45San Antonio AirportSan Antonio Airport04:36Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 26/01/2026 16:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 27/01/2026 04:36:00. 50 Economy ticket for £212 per person are available. Travel duration is 11h 51m
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Spirit Airlines13h 28m006:30San Antonio AirportSan Antonio Airport19:58Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/01/2026 06:30:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 26/01/2026 19:58:00. 50 Economy ticket for £236 per person are available. Travel duration is 13h 28m
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Aeroméxico16h 16m012:20San Antonio AirportSan Antonio Airport04:36Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Aeroméxico goes from San Antonio Airport, San Antonio Airport (USA) at 26/01/2026 12:20:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 27/01/2026 04:36:00. 50 Economy ticket for £289 per person are available. Travel duration is 16h 16m
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Frontier Airlines17h 52m018:13San Antonio AirportSan Antonio Airport12:05Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/01/2026 18:13:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 27/01/2026 12:05:00. 50 Economy ticket for £187 per person are available. Travel duration is 17h 52m
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Frontier Airlines19h 45m018:13San Antonio AirportSan Antonio Airport13:58Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/01/2026 18:13:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 27/01/2026 13:58:00. 50 Economy ticket for £187 per person are available. Travel duration is 19h 45m
Fastest Flights Monday
Here you will find all operators and timetables for a
Bus from San Antonio, TX to Chicago
What are the most popular stations in San Antonio, TX and Chicago?
In San Antonio, TX, you will usually depart from Tornado Bus Company, Coach Station or W. Southcross & Buffalo Bus Stop, while in Chicago you will be arriving at California & 35th Street Coach Stop, Downtown Coach Station or 95th Red Line Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Chicago from San Antonio, TX? With 7 connections between 3 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between San Antonio, TX and Chicago, you can pay as low as £105 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Chicago in just 2h 51m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting San Antonio, TX and Chicago are Greyhound Lines Mexico, Spirit Airlines and Greyhound US, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in San Antonio, TX and Chicago is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Olmos Park, TX or to Cicero, IL, and look at flights from San Antonio Airport, and landing at Chicago Midway Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from San Antonio, TX to Chicago?
The most popular companies between San Antonio, TX and Chicago, are Greyhound Lines Mexico, Spirit Airlines and Greyhound US. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound Lines Mexico, Greyhound US and FlixBus
Airlines: Spirit Airlines, Frontier Airlines, Volaris and 3 more.
All you need to know when you travel from San Antonio, TX to Chicago
Check all information on comfort and services on all modes of transports from San Antonio, TX to Chicago. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from San Antonio, TX to Chicago
How can I reach Chicago from San Antonio, TX?
Every day, there are on average 7 connections between Bus and Flight, with which you can get to Chicago from San Antonio, TX.
How far is Chicago from San Antonio, TX?
The distance between San Antonio, TX and Chicago is 1,692.8 km.
What is the most ecofriendly mode of transport between San Antonio, TX and Chicago?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 46 kgs of CO2, a train 59 kgs, a car 288 kgs, and a flight 416 kgs.
What is the cheapest mode of transport from San Antonio, TX to Chicago?
You can get to Chicago with just £105 by taking a Bus from Greyhound US.
What is the fastest way to get from San Antonio, TX to Chicago?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Chicago in just 2h 51m with a Flight from United Airlines.
More routes to San Antonio, TX and to Chicago
Looking for more options? Here you can see the most popular routes to San Antonio, TX and to Chicago. Simply click on a connection, and you’ll find all the details about the route!
- Trips to San Antonio, TX
- Aguascalientes to San Antonio, TX
- Brownsville, TX to San Antonio, TX
- Ciudad Juárez to San Antonio, TX
- Dallas to San Antonio, TX
- El Paso, TX to San Antonio, TX
- Guadalajara, JC to San Antonio, TX
- Houston to San Antonio, TX
- Las Vegas to San Antonio, TX
- McAllen, TX to San Antonio, TX
- Mexico City to San Antonio, TX
- Monterrey, NL to San Antonio, TX
- Phoenix, AZ to San Antonio, TX
- Reynosa to San Antonio, TX
- Saltillo to San Antonio, TX
- San Luis Potosí to San Antonio, TX
- Santiago de Queretaro to San Antonio, TX
- St. Louis, MO to San Antonio, TX
- Torreón, CO to San Antonio, TX
- Washington, DC to San Antonio, TX
- Zacatecas, ZS to San Antonio, TX
- Trips to Chicago
- Aguascalientes to Chicago
- Atlanta, GA to Chicago
- Bloomington, IN to Chicago
- Buffalo, NY to Chicago
- Cincinnati to Chicago
- Dallas to Chicago
- Durango, DG to Chicago
- El Paso, TX to Chicago
- Houston to Chicago
- Los Angeles to Chicago
- Louisville, KY to Chicago
- Memphis to Chicago
- Mexico City to Chicago
- Mississauga, ON to Chicago
- Monterrey, NL to Chicago
- Nashville to Chicago
- New York to Chicago
- Pearson Toronto Airport to Chicago
- Santiago de Queretaro to Chicago
- St. Louis, MO to Chicago
- Toronto, ON to Chicago
- Tulsa to Chicago
- Zacatecas, ZS to Chicago
