What is the best way to travel from San Antonio, TX to Chicago?
Looking for a trip? Check and compare all the available Buses and Flights to Chicago from San Antonio, TX. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 6 available companies to find your perfect trip!
What is the cheapest way to reach Chicago from San Antonio, TX?
You can reach Chicago with just £82 by taking a Bus from Greyhound Lines Mexico, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Greyhound Lines Mexico27h 50m001:30San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 20/04/2026 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 21/04/2026 05:20:00. 50 Economy ticket for £82 per person are available. Travel duration is 27h 50m
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Greyhound Lines Mexico34h 5m019:15San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 20/04/2026 19:15:00 to 95th Red Line Station, Chicago (USA) arriving at 22/04/2026 05:20:00. 50 Economy ticket for £83 per person are available. Travel duration is 34h 5m
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Greyhound US35h 0m012:35San Antonio, TXCoach Station23:35Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 20/04/2026 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 21/04/2026 23:35:00. 50 Economy ticket for £83 per person are available. Travel duration is 35h 0m
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FlixBus35h 5m007:30San Antonio, TXCoach Station18:35Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 20/04/2026 07:30:00 to 95th Red Line Station, Chicago (USA) arriving at 21/04/2026 18:35:00. 50 Economy ticket for £84 per person are available. Travel duration is 35h 5m
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FlixBus34h 50m007:45San Antonio, TXPearl District18:35Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 20/04/2026 07:45:00 to 95th Red Line Station, Chicago (USA) arriving at 21/04/2026 18:35:00. 50 Economy ticket for £84 per person are available. Travel duration is 34h 50m
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Frontier Airlines29h 40m013:51San Antonio AirportSan Antonio Airport19:31Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 20/04/2026 13:51:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 21/04/2026 19:31:00. 50 Economy ticket for £106 per person are available. Travel duration is 29h 40m
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United Airlines2h 55m006:49San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 20/04/2026 06:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 20/04/2026 09:44:00. 50 Economy ticket for £117 per person are available. Travel duration is 2h 55m
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Spirit Airlines37h 31m006:00San Antonio AirportSan Antonio Airport19:31Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 20/04/2026 06:00:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 21/04/2026 19:31:00. 50 Economy ticket for £120 per person are available. Travel duration is 37h 31m
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Spirit Airlines29h 19m014:12San Antonio AirportSan Antonio Airport19:31Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 20/04/2026 14:12:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 21/04/2026 19:31:00. 50 Economy ticket for £124 per person are available. Travel duration is 29h 19m
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Spirit Airlines17h 55m006:00San Antonio AirportSan Antonio Airport23:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 20/04/2026 06:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 20/04/2026 23:55:00. 50 Economy ticket for £133 per person are available. Travel duration is 17h 55m
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Frontier Airlines31h 14m015:00San Antonio AirportSan Antonio Airport22:14Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 20/04/2026 15:00:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 21/04/2026 22:14:00. 50 Economy ticket for £138 per person are available. Travel duration is 31h 14m
Cheapest Buses Monday
Cheapest Flights Monday
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Greyhound Lines Mexico27h 50m001:30San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 21/04/2026 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 22/04/2026 05:20:00. 50 Economy ticket for £100 per person are available. Travel duration is 27h 50m
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Greyhound Lines Mexico36h 45m005:50San Antonio, TXCoach Station18:35Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 21/04/2026 05:50:00 to 95th Red Line Station, Chicago (USA) arriving at 22/04/2026 18:35:00. 50 Economy ticket for £100 per person are available. Travel duration is 36h 45m
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Greyhound Lines Mexico34h 5m019:15San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 21/04/2026 19:15:00 to 95th Red Line Station, Chicago (USA) arriving at 23/04/2026 05:20:00. 50 Economy ticket for £100 per person are available. Travel duration is 34h 5m
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Greyhound US35h 0m012:35San Antonio, TXCoach Station23:35Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 21/04/2026 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 22/04/2026 23:35:00. 50 Economy ticket for £100 per person are available. Travel duration is 35h 0m
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Frontier Airlines27h 27m016:04San Antonio AirportSan Antonio Airport19:31Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 21/04/2026 16:04:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 22/04/2026 19:31:00. 50 Economy ticket for £102 per person are available. Travel duration is 27h 27m
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United Airlines2h 55m006:49San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 21/04/2026 06:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/04/2026 09:44:00. 50 Economy ticket for £127 per person are available. Travel duration is 2h 55m
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Viva Aerobus12h 7m017:45San Antonio AirportSan Antonio Airport05:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 21/04/2026 17:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 05:52:00. 50 Economy ticket for £195 per person are available. Travel duration is 12h 7m
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Volaris14h 9m020:41San Antonio AirportSan Antonio Airport10:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 21/04/2026 20:41:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 10:50:00. 50 Economy ticket for £210 per person are available. Travel duration is 14h 9m
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Volaris19h 45m020:41San Antonio AirportSan Antonio Airport16:26Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 21/04/2026 20:41:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 22/04/2026 16:26:00. 50 Economy ticket for £249 per person are available. Travel duration is 19h 45m
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Delta Air Lines28h 55m005:20San Antonio AirportSan Antonio Airport10:15Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Delta Air Lines goes from San Antonio Airport, San Antonio Airport (USA) at 21/04/2026 05:20:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 22/04/2026 10:15:00. 50 Economy ticket for £259 per person are available. Travel duration is 28h 55m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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Greyhound US31h 35m012:35San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 22/04/2026 12:35:00 to Downtown Coach Station, Chicago (USA) arriving at 23/04/2026 20:10:00. 50 Economy ticket for £104 per person are available. Travel duration is 31h 35m
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Greyhound Lines Mexico30h 30m001:30San Antonio, TXCoach Station08:00ChicagoUnion Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 22/04/2026 01:30:00 to Union Station, Chicago (USA) arriving at 23/04/2026 08:00:00. 50 Economy ticket for £106 per person are available. Travel duration is 30h 30m
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Greyhound Lines Mexico26h 40m001:30San Antonio, TXCoach Station04:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 22/04/2026 01:30:00 to Downtown Coach Station, Chicago (USA) arriving at 23/04/2026 04:10:00. 50 Economy ticket for £106 per person are available. Travel duration is 26h 40m
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FlixBus51h 45m007:45San Antonio, TXPearl District11:30ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 22/04/2026 07:45:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 11:30:00. 50 Economy ticket for £106 per person are available. Travel duration is 51h 45m
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United Airlines2h 55m006:49San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 22/04/2026 06:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 09:44:00. 50 Economy ticket for £127 per person are available. Travel duration is 2h 55m
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Spirit Airlines17h 14m014:12San Antonio AirportSan Antonio Airport07:26Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 22/04/2026 14:12:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 23/04/2026 07:26:00. 50 Economy ticket for £137 per person are available. Travel duration is 17h 14m
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Spirit Airlines18h 53m014:12San Antonio AirportSan Antonio Airport09:05Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 22/04/2026 14:12:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/04/2026 09:05:00. 50 Economy ticket for £137 per person are available. Travel duration is 18h 53m
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Volaris25h 59m022:16San Antonio AirportSan Antonio Airport00:15Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 22/04/2026 22:16:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 00:15:00. 50 Economy ticket for £207 per person are available. Travel duration is 25h 59m
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Viva Aerobus12h 7m017:45San Antonio AirportSan Antonio Airport05:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 22/04/2026 17:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/04/2026 05:52:00. 50 Economy ticket for £217 per person are available. Travel duration is 12h 7m
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Aeroméxico9h 57m013:50San Antonio AirportSan Antonio Airport23:47Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Aeroméxico goes from San Antonio Airport, San Antonio Airport (USA) at 22/04/2026 13:50:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 23:47:00. 50 Economy ticket for £287 per person are available. Travel duration is 9h 57m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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FlixBus48h 15m007:45San Antonio, TXPearl District08:00ChicagoUnion Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 23/04/2026 07:45:00 to Union Station, Chicago (USA) arriving at 25/04/2026 08:00:00. 50 Economy ticket for £98 per person are available. Travel duration is 48h 15m
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Greyhound US31h 35m012:35San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 23/04/2026 12:35:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 20:10:00. 50 Economy ticket for £98 per person are available. Travel duration is 31h 35m
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Greyhound Lines Mexico30h 30m001:30San Antonio, TXCoach Station08:00ChicagoUnion Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 23/04/2026 01:30:00 to Union Station, Chicago (USA) arriving at 24/04/2026 08:00:00. 50 Economy ticket for £99 per person are available. Travel duration is 30h 30m
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Greyhound Lines Mexico26h 50m001:30San Antonio, TXCoach Station04:20ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 23/04/2026 01:30:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 04:20:00. 50 Economy ticket for £99 per person are available. Travel duration is 26h 50m
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FlixBus32h 20m007:45San Antonio, TXPearl District16:05ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 23/04/2026 07:45:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 16:05:00. 50 Economy ticket for £101 per person are available. Travel duration is 32h 20m
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Spirit Airlines18h 24m006:00San Antonio AirportSan Antonio Airport00:24Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/04/2026 06:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 00:24:00. 50 Economy ticket for £115 per person are available. Travel duration is 18h 24m
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United Airlines2h 55m006:49San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/04/2026 06:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/04/2026 09:44:00. 50 Economy ticket for £137 per person are available. Travel duration is 2h 55m
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Spirit Airlines27h 42m014:12San Antonio AirportSan Antonio Airport17:54Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/04/2026 14:12:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 24/04/2026 17:54:00. 50 Economy ticket for £181 per person are available. Travel duration is 27h 42m
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Viva Aerobus12h 7m017:45San Antonio AirportSan Antonio Airport05:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 23/04/2026 17:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 05:52:00. 50 Economy ticket for £204 per person are available. Travel duration is 12h 7m
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Volaris14h 9m020:41San Antonio AirportSan Antonio Airport10:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 23/04/2026 20:41:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 10:50:00. 50 Economy ticket for £233 per person are available. Travel duration is 14h 9m
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Frontier Airlines17h 22m012:46San Antonio AirportSan Antonio Airport06:08Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/04/2026 12:46:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 06:08:00. 50 Economy ticket for £234 per person are available. Travel duration is 17h 22m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Spirit Airlines17h 54m006:00San Antonio AirportSan Antonio Airport23:54Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/04/2026 06:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 23:54:00. 50 Economy ticket for £115 per person are available. Travel duration is 17h 54m
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Spirit Airlines26h 1m014:12San Antonio AirportSan Antonio Airport16:13Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/04/2026 14:12:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 25/04/2026 16:13:00. 50 Economy ticket for £146 per person are available. Travel duration is 26h 1m
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United Airlines2h 55m006:49San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/04/2026 06:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 09:44:00. 50 Economy ticket for £146 per person are available. Travel duration is 2h 55m
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Frontier Airlines16h 39m012:46San Antonio AirportSan Antonio Airport05:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/04/2026 12:46:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 05:25:00. 50 Economy ticket for £205 per person are available. Travel duration is 16h 39m
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Viva Aerobus12h 7m017:45San Antonio AirportSan Antonio Airport05:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 24/04/2026 17:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 05:52:00. 50 Economy ticket for £221 per person are available. Travel duration is 12h 7m
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Volaris12h 34m022:16San Antonio AirportSan Antonio Airport10:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 24/04/2026 22:16:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 10:50:00. 50 Economy ticket for £244 per person are available. Travel duration is 12h 34m
Cheapest Flights Friday
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United Airlines2h 55m006:49San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 25/04/2026 06:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 09:44:00. 50 Economy ticket for £105 per person are available. Travel duration is 2h 55m
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Spirit Airlines8h 55m014:12San Antonio AirportSan Antonio Airport23:07Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 25/04/2026 14:12:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 23:07:00. 50 Economy ticket for £108 per person are available. Travel duration is 8h 55m
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Spirit Airlines12h 37m006:00San Antonio AirportSan Antonio Airport18:37Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 25/04/2026 06:00:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 25/04/2026 18:37:00. 50 Economy ticket for £118 per person are available. Travel duration is 12h 37m
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Frontier Airlines17h 54m016:04San Antonio AirportSan Antonio Airport09:58Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 25/04/2026 16:04:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 26/04/2026 09:58:00. 50 Economy ticket for £135 per person are available. Travel duration is 17h 54m
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Spirit Airlines19h 46m014:12San Antonio AirportSan Antonio Airport09:58Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 25/04/2026 14:12:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 26/04/2026 09:58:00. 50 Economy ticket for £138 per person are available. Travel duration is 19h 46m
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Aeroméxico9h 57m013:50San Antonio AirportSan Antonio Airport23:47Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Aeroméxico goes from San Antonio Airport, San Antonio Airport (USA) at 25/04/2026 13:50:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 23:47:00. 50 Economy ticket for £288 per person are available. Travel duration is 9h 57m
Cheapest Flights Saturday
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FlixBus35h 5m007:30San Antonio, TXCoach Station18:35Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 26/04/2026 07:30:00 to 95th Red Line Station, Chicago (USA) arriving at 27/04/2026 18:35:00. 50 Economy ticket for £96 per person are available. Travel duration is 35h 5m
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Greyhound US35h 0m012:35San Antonio, TXCoach Station23:35Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 26/04/2026 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 27/04/2026 23:35:00. 50 Economy ticket for £96 per person are available. Travel duration is 35h 0m
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Greyhound Lines Mexico27h 50m001:30San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 26/04/2026 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 27/04/2026 05:20:00. 50 Economy ticket for £97 per person are available. Travel duration is 27h 50m
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Valley Transit32h 5m021:15San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Coach Station, San Antonio, TX (USA) at 26/04/2026 21:15:00 to 95th Red Line Station, Chicago (USA) arriving at 28/04/2026 05:20:00. 50 Economy ticket for £97 per person are available. Travel duration is 32h 5m
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Tornado Bus Company23h 50m011:05San Antonio, TXTornado Bus Company10:55ChicagoCalifornia & 35th Street Coach Stop0BasicA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 26/04/2026 11:05:00 to California & 35th Street Coach Stop, Chicago (USA) arriving at 27/04/2026 10:55:00. 50 Basic ticket for £189 per person are available. Travel duration is 23h 50m
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Spirit Airlines17h 55m006:00San Antonio AirportSan Antonio Airport23:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/04/2026 06:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 23:55:00. 50 Economy ticket for £133 per person are available. Travel duration is 17h 55m
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Spirit Airlines8h 55m014:12San Antonio AirportSan Antonio Airport23:07Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/04/2026 14:12:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 23:07:00. 50 Economy ticket for £166 per person are available. Travel duration is 8h 55m
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United Airlines2h 55m006:49San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/04/2026 06:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 09:44:00. 50 Economy ticket for £169 per person are available. Travel duration is 2h 55m
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United Airlines7h 24m018:02San Antonio AirportSan Antonio Airport01:26Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/04/2026 18:02:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 27/04/2026 01:26:00. 50 Economy ticket for £176 per person are available. Travel duration is 7h 24m
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Spirit Airlines17h 52m014:12San Antonio AirportSan Antonio Airport08:04Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/04/2026 14:12:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 27/04/2026 08:04:00. 50 Economy ticket for £190 per person are available. Travel duration is 17h 52m
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Viva Aerobus12h 7m017:45San Antonio AirportSan Antonio Airport05:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 26/04/2026 17:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 27/04/2026 05:52:00. 50 Economy ticket for £271 per person are available. Travel duration is 12h 7m
Cheapest Buses Sunday
Cheapest Flights Sunday
What are the fastest trips from San Antonio, TX to Chicago?
You can get to Chicago from San Antonio, TX in just 2h 55m with a Flight from United Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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United Airlines2h 55m006:49San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 20/04/2026 06:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 20/04/2026 09:44:00. 50 Economy ticket for £117 per person are available. Travel duration is 2h 55m
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Frontier Airlines9h 16m013:51San Antonio AirportSan Antonio Airport23:07Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 20/04/2026 13:51:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 20/04/2026 23:07:00. 50 Economy ticket for £223 per person are available. Travel duration is 9h 16m
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Alaska Airlines12h 49m017:50San Antonio AirportSan Antonio Airport06:39Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Alaska Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 20/04/2026 17:50:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/04/2026 06:39:00. 50 Economy ticket for £322 per person are available. Travel duration is 12h 49m
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Hawaiian Airlines12h 49m017:50San Antonio AirportSan Antonio Airport06:39Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Hawaiian Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 20/04/2026 17:50:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/04/2026 06:39:00. 50 Economy ticket for £332 per person are available. Travel duration is 12h 49m
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Delta Air Lines17h 45m016:30San Antonio AirportSan Antonio Airport10:15Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Delta Air Lines goes from San Antonio Airport, San Antonio Airport (USA) at 20/04/2026 16:30:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 21/04/2026 10:15:00. 50 Economy ticket for £252 per person are available. Travel duration is 17h 45m
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Spirit Airlines17h 55m006:00San Antonio AirportSan Antonio Airport23:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 20/04/2026 06:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 20/04/2026 23:55:00. 50 Economy ticket for £133 per person are available. Travel duration is 17h 55m
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Greyhound Lines Mexico27h 50m001:30San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 20/04/2026 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 21/04/2026 05:20:00. 50 Economy ticket for £82 per person are available. Travel duration is 27h 50m
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Greyhound Lines Mexico34h 5m019:15San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 20/04/2026 19:15:00 to 95th Red Line Station, Chicago (USA) arriving at 22/04/2026 05:20:00. 50 Economy ticket for £83 per person are available. Travel duration is 34h 5m
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FlixBus34h 50m007:45San Antonio, TXPearl District18:35Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 20/04/2026 07:45:00 to 95th Red Line Station, Chicago (USA) arriving at 21/04/2026 18:35:00. 50 Economy ticket for £84 per person are available. Travel duration is 34h 50m
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Greyhound US35h 0m012:35San Antonio, TXCoach Station23:35Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 20/04/2026 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 21/04/2026 23:35:00. 50 Economy ticket for £83 per person are available. Travel duration is 35h 0m
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FlixBus35h 5m007:30San Antonio, TXCoach Station18:35Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 20/04/2026 07:30:00 to 95th Red Line Station, Chicago (USA) arriving at 21/04/2026 18:35:00. 50 Economy ticket for £84 per person are available. Travel duration is 35h 5m
Fastest Flights Monday
Fastest Buses Monday
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United Airlines2h 55m006:49San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 21/04/2026 06:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 21/04/2026 09:44:00. 50 Economy ticket for £127 per person are available. Travel duration is 2h 55m
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Viva Aerobus12h 7m017:45San Antonio AirportSan Antonio Airport05:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 21/04/2026 17:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 05:52:00. 50 Economy ticket for £195 per person are available. Travel duration is 12h 7m
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Alaska Airlines12h 50m017:50San Antonio AirportSan Antonio Airport06:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Alaska Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 21/04/2026 17:50:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 06:40:00. 50 Economy ticket for £261 per person are available. Travel duration is 12h 50m
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Volaris14h 9m020:41San Antonio AirportSan Antonio Airport10:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 21/04/2026 20:41:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 10:50:00. 50 Economy ticket for £210 per person are available. Travel duration is 14h 9m
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Aeroméxico16h 2m013:50San Antonio AirportSan Antonio Airport05:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Aeroméxico goes from San Antonio Airport, San Antonio Airport (USA) at 21/04/2026 13:50:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 05:52:00. 50 Economy ticket for £265 per person are available. Travel duration is 16h 2m
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Volaris19h 45m020:41San Antonio AirportSan Antonio Airport16:26Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 21/04/2026 20:41:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 22/04/2026 16:26:00. 50 Economy ticket for £249 per person are available. Travel duration is 19h 45m
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Greyhound Lines Mexico27h 50m001:30San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 21/04/2026 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 22/04/2026 05:20:00. 50 Economy ticket for £100 per person are available. Travel duration is 27h 50m
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Greyhound Lines Mexico34h 5m019:15San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 21/04/2026 19:15:00 to 95th Red Line Station, Chicago (USA) arriving at 23/04/2026 05:20:00. 50 Economy ticket for £100 per person are available. Travel duration is 34h 5m
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Greyhound US35h 0m012:35San Antonio, TXCoach Station23:35Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 21/04/2026 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 22/04/2026 23:35:00. 50 Economy ticket for £100 per person are available. Travel duration is 35h 0m
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Greyhound Lines Mexico36h 45m005:50San Antonio, TXCoach Station18:35Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 21/04/2026 05:50:00 to 95th Red Line Station, Chicago (USA) arriving at 22/04/2026 18:35:00. 50 Economy ticket for £100 per person are available. Travel duration is 36h 45m
Fastest Flights Tuesday
Fastest Buses Tuesday
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United Airlines2h 55m006:49San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 22/04/2026 06:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 09:44:00. 50 Economy ticket for £127 per person are available. Travel duration is 2h 55m
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Aeroméxico9h 57m013:50San Antonio AirportSan Antonio Airport23:47Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Aeroméxico goes from San Antonio Airport, San Antonio Airport (USA) at 22/04/2026 13:50:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 22/04/2026 23:47:00. 50 Economy ticket for £287 per person are available. Travel duration is 9h 57m
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Viva Aerobus12h 7m017:45San Antonio AirportSan Antonio Airport05:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 22/04/2026 17:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/04/2026 05:52:00. 50 Economy ticket for £217 per person are available. Travel duration is 12h 7m
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Spirit Airlines17h 14m014:12San Antonio AirportSan Antonio Airport07:26Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 22/04/2026 14:12:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 23/04/2026 07:26:00. 50 Economy ticket for £137 per person are available. Travel duration is 17h 14m
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Spirit Airlines18h 53m014:12San Antonio AirportSan Antonio Airport09:05Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 22/04/2026 14:12:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/04/2026 09:05:00. 50 Economy ticket for £137 per person are available. Travel duration is 18h 53m
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Volaris25h 59m022:16San Antonio AirportSan Antonio Airport00:15Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 22/04/2026 22:16:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 00:15:00. 50 Economy ticket for £207 per person are available. Travel duration is 25h 59m
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Greyhound Lines Mexico26h 40m001:30San Antonio, TXCoach Station04:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 22/04/2026 01:30:00 to Downtown Coach Station, Chicago (USA) arriving at 23/04/2026 04:10:00. 50 Economy ticket for £106 per person are available. Travel duration is 26h 40m
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Greyhound Lines Mexico30h 30m001:30San Antonio, TXCoach Station08:00ChicagoUnion Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 22/04/2026 01:30:00 to Union Station, Chicago (USA) arriving at 23/04/2026 08:00:00. 50 Economy ticket for £106 per person are available. Travel duration is 30h 30m
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Greyhound US31h 35m012:35San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 22/04/2026 12:35:00 to Downtown Coach Station, Chicago (USA) arriving at 23/04/2026 20:10:00. 50 Economy ticket for £104 per person are available. Travel duration is 31h 35m
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FlixBus51h 45m007:45San Antonio, TXPearl District11:30ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 22/04/2026 07:45:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 11:30:00. 50 Economy ticket for £106 per person are available. Travel duration is 51h 45m
Fastest Flights Wednesday
Fastest Buses Wednesday
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United Airlines2h 55m006:49San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/04/2026 06:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 23/04/2026 09:44:00. 50 Economy ticket for £137 per person are available. Travel duration is 2h 55m
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Viva Aerobus12h 7m017:45San Antonio AirportSan Antonio Airport05:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 23/04/2026 17:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 05:52:00. 50 Economy ticket for £204 per person are available. Travel duration is 12h 7m
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Volaris14h 9m020:41San Antonio AirportSan Antonio Airport10:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 23/04/2026 20:41:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 10:50:00. 50 Economy ticket for £233 per person are available. Travel duration is 14h 9m
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Frontier Airlines17h 22m012:46San Antonio AirportSan Antonio Airport06:08Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/04/2026 12:46:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 06:08:00. 50 Economy ticket for £234 per person are available. Travel duration is 17h 22m
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Spirit Airlines18h 24m006:00San Antonio AirportSan Antonio Airport00:24Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/04/2026 06:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 00:24:00. 50 Economy ticket for £115 per person are available. Travel duration is 18h 24m
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Spirit Airlines27h 42m014:12San Antonio AirportSan Antonio Airport17:54Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 23/04/2026 14:12:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 24/04/2026 17:54:00. 50 Economy ticket for £181 per person are available. Travel duration is 27h 42m
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Greyhound Lines Mexico26h 50m001:30San Antonio, TXCoach Station04:20ChicagoDowntown Coach Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 23/04/2026 01:30:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 04:20:00. 50 Economy ticket for £99 per person are available. Travel duration is 26h 50m
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Greyhound Lines Mexico30h 30m001:30San Antonio, TXCoach Station08:00ChicagoUnion Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 23/04/2026 01:30:00 to Union Station, Chicago (USA) arriving at 24/04/2026 08:00:00. 50 Economy ticket for £99 per person are available. Travel duration is 30h 30m
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Greyhound US31h 35m012:35San Antonio, TXCoach Station20:10ChicagoDowntown Coach Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 23/04/2026 12:35:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 20:10:00. 50 Economy ticket for £98 per person are available. Travel duration is 31h 35m
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FlixBus32h 20m007:45San Antonio, TXPearl District16:05ChicagoDowntown Coach Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 23/04/2026 07:45:00 to Downtown Coach Station, Chicago (USA) arriving at 24/04/2026 16:05:00. 50 Economy ticket for £101 per person are available. Travel duration is 32h 20m
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FlixBus48h 15m007:45San Antonio, TXPearl District08:00ChicagoUnion Station0EconomyA Bus from FlixBus goes from Pearl District, San Antonio, TX (USA) at 23/04/2026 07:45:00 to Union Station, Chicago (USA) arriving at 25/04/2026 08:00:00. 50 Economy ticket for £98 per person are available. Travel duration is 48h 15m
Fastest Flights Thursday
Fastest Buses Thursday
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United Airlines2h 55m006:49San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/04/2026 06:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 09:44:00. 50 Economy ticket for £146 per person are available. Travel duration is 2h 55m
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Viva Aerobus12h 7m017:45San Antonio AirportSan Antonio Airport05:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 24/04/2026 17:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 05:52:00. 50 Economy ticket for £221 per person are available. Travel duration is 12h 7m
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Volaris12h 34m022:16San Antonio AirportSan Antonio Airport10:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 24/04/2026 22:16:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 10:50:00. 50 Economy ticket for £244 per person are available. Travel duration is 12h 34m
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Frontier Airlines16h 39m012:46San Antonio AirportSan Antonio Airport05:25Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Frontier Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/04/2026 12:46:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 05:25:00. 50 Economy ticket for £205 per person are available. Travel duration is 16h 39m
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Spirit Airlines17h 54m006:00San Antonio AirportSan Antonio Airport23:54Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/04/2026 06:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 24/04/2026 23:54:00. 50 Economy ticket for £115 per person are available. Travel duration is 17h 54m
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Spirit Airlines26h 1m014:12San Antonio AirportSan Antonio Airport16:13Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 24/04/2026 14:12:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 25/04/2026 16:13:00. 50 Economy ticket for £146 per person are available. Travel duration is 26h 1m
Fastest Flights Friday
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United Airlines2h 55m006:49San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 25/04/2026 06:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 09:44:00. 50 Economy ticket for £105 per person are available. Travel duration is 2h 55m
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Spirit Airlines8h 55m014:12San Antonio AirportSan Antonio Airport23:07Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 25/04/2026 14:12:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 23:07:00. 50 Economy ticket for £108 per person are available. Travel duration is 8h 55m
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Aeroméxico9h 57m013:50San Antonio AirportSan Antonio Airport23:47Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Aeroméxico goes from San Antonio Airport, San Antonio Airport (USA) at 25/04/2026 13:50:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 25/04/2026 23:47:00. 50 Economy ticket for £288 per person are available. Travel duration is 9h 57m
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Spirit Airlines12h 37m006:00San Antonio AirportSan Antonio Airport18:37Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 25/04/2026 06:00:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 25/04/2026 18:37:00. 50 Economy ticket for £118 per person are available. Travel duration is 12h 37m
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Alaska Airlines12h 39m018:01San Antonio AirportSan Antonio Airport06:40Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Alaska Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 25/04/2026 18:01:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 06:40:00. 50 Economy ticket for £338 per person are available. Travel duration is 12h 39m
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Volaris14h 9m020:41San Antonio AirportSan Antonio Airport10:50Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Volaris goes from San Antonio Airport, San Antonio Airport (USA) at 25/04/2026 20:41:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 10:50:00. 50 Economy ticket for £420 per person are available. Travel duration is 14h 9m
Fastest Flights Saturday
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United Airlines2h 55m006:49San Antonio AirportSan Antonio Airport09:44Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/04/2026 06:49:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 09:44:00. 50 Economy ticket for £169 per person are available. Travel duration is 2h 55m
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United Airlines7h 24m018:02San Antonio AirportSan Antonio Airport01:26Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from United Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/04/2026 18:02:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 27/04/2026 01:26:00. 50 Economy ticket for £176 per person are available. Travel duration is 7h 24m
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Spirit Airlines8h 55m014:12San Antonio AirportSan Antonio Airport23:07Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/04/2026 14:12:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 23:07:00. 50 Economy ticket for £166 per person are available. Travel duration is 8h 55m
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Viva Aerobus12h 7m017:45San Antonio AirportSan Antonio Airport05:52Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Viva Aerobus goes from San Antonio Airport, San Antonio Airport (USA) at 26/04/2026 17:45:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 27/04/2026 05:52:00. 50 Economy ticket for £271 per person are available. Travel duration is 12h 7m
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Spirit Airlines17h 52m014:12San Antonio AirportSan Antonio Airport08:04Chicago Midway AirportChicago Midway Airport0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/04/2026 14:12:00 to Chicago Midway Airport, Chicago Midway Airport (USA) arriving at 27/04/2026 08:04:00. 50 Economy ticket for £190 per person are available. Travel duration is 17h 52m
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Spirit Airlines17h 55m006:00San Antonio AirportSan Antonio Airport23:55Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center0EconomyA Flight from Spirit Airlines goes from San Antonio Airport, San Antonio Airport (USA) at 26/04/2026 06:00:00 to Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) arriving at 26/04/2026 23:55:00. 50 Economy ticket for £133 per person are available. Travel duration is 17h 55m
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Tornado Bus Company23h 50m011:05San Antonio, TXTornado Bus Company10:55ChicagoCalifornia & 35th Street Coach Stop0BasicA Bus from Tornado Bus Company goes from Tornado Bus Company, San Antonio, TX (USA) at 26/04/2026 11:05:00 to California & 35th Street Coach Stop, Chicago (USA) arriving at 27/04/2026 10:55:00. 50 Basic ticket for £189 per person are available. Travel duration is 23h 50m
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Greyhound Lines Mexico27h 50m001:30San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Greyhound Lines Mexico goes from Coach Station, San Antonio, TX (USA) at 26/04/2026 01:30:00 to 95th Red Line Station, Chicago (USA) arriving at 27/04/2026 05:20:00. 50 Economy ticket for £97 per person are available. Travel duration is 27h 50m
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Valley Transit32h 5m021:15San Antonio, TXCoach Station05:20Chicago95th Red Line Station0EconomyA Bus from Valley Transit goes from Coach Station, San Antonio, TX (USA) at 26/04/2026 21:15:00 to 95th Red Line Station, Chicago (USA) arriving at 28/04/2026 05:20:00. 50 Economy ticket for £97 per person are available. Travel duration is 32h 5m
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Greyhound US35h 0m012:35San Antonio, TXCoach Station23:35Chicago95th Red Line Station0EconomyA Bus from Greyhound US goes from Coach Station, San Antonio, TX (USA) at 26/04/2026 12:35:00 to 95th Red Line Station, Chicago (USA) arriving at 27/04/2026 23:35:00. 50 Economy ticket for £96 per person are available. Travel duration is 35h 0m
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FlixBus35h 5m007:30San Antonio, TXCoach Station18:35Chicago95th Red Line Station0EconomyA Bus from FlixBus goes from Coach Station, San Antonio, TX (USA) at 26/04/2026 07:30:00 to 95th Red Line Station, Chicago (USA) arriving at 27/04/2026 18:35:00. 50 Economy ticket for £96 per person are available. Travel duration is 35h 5m
Fastest Flights Sunday
Fastest Buses Sunday
Here you will find all operators and timetables for a
Bus from San Antonio, TX to Chicago
What are the most popular stations in San Antonio, TX and Chicago?
In San Antonio, TX, you will usually depart from W. Southcross & Buffalo Bus Stop, Coach Station or Tornado Bus Company, while in Chicago you will be arriving at Downtown Coach Station, 95th Red Line Station or California & 35th Street Coach Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Chicago from San Antonio, TX? With 11 connections between 6 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between San Antonio, TX and Chicago, you can pay as low as £82 with a Bus from Greyhound Lines Mexico.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Chicago in just 2h 55m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting San Antonio, TX and Chicago are Spirit Airlines, Greyhound Lines Mexico and United Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in San Antonio, TX and Chicago is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Olmos Park, TX or to Cicero, IL, and look at flights from San Antonio Airport, and landing at Chicago Midway Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from San Antonio, TX to Chicago?
The most popular companies between San Antonio, TX and Chicago, are Spirit Airlines, Greyhound Lines Mexico and United Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound Lines Mexico, FlixBus, Greyhound US and 2 more.
Airlines: Spirit Airlines, United Airlines, Frontier Airlines and 6 more.
All you need to know when you travel from San Antonio, TX to Chicago
Check all information on comfort and services on all modes of transports from San Antonio, TX to Chicago. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from San Antonio, TX to Chicago
How can I reach Chicago from San Antonio, TX?
Every day, there are on average 11 connections between Flight and Bus, with which you can get to Chicago from San Antonio, TX.
How far is Chicago from San Antonio, TX?
The distance between San Antonio, TX and Chicago is 1,692.8 km.
What is the most ecofriendly mode of transport between San Antonio, TX and Chicago?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 46 kgs of CO2, a train 59 kgs, a car 288 kgs, and a flight 416 kgs.
What is the cheapest mode of transport from San Antonio, TX to Chicago?
You can get to Chicago with just £82 by taking a Bus from Greyhound Lines Mexico.
What is the fastest way to get from San Antonio, TX to Chicago?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Chicago in just 2h 55m with a Flight from United Airlines.
More routes to San Antonio, TX and to Chicago
Looking for more options? Here you can see the most popular routes to San Antonio, TX and to Chicago. Simply click on a connection, and you’ll find all the details about the route!
