What is the best way to travel from Chicago to San Antonio, TX?
Looking for a trip? Check and compare all the available Buses and Flights to San Antonio, TX from Chicago. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach San Antonio, TX from Chicago?
You can reach San Antonio, TX with just £109 by taking a Bus from Greyhound US, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus28h 45m000:15ChicagoDowntown Coach Station05:00San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 05/07/2025 00:15:00 to Coach Station, San Antonio, TX (USA) arriving at 06/07/2025 05:00:00. 50 Economy ticket for £185 per person are available. Travel duration is 28h 45m
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FlixBus37h 25m009:45ChicagoDowntown Coach Station23:10San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 05/07/2025 09:45:00 to Pearl District, San Antonio, TX (USA) arriving at 06/07/2025 23:10:00. 50 Economy ticket for £186 per person are available. Travel duration is 37h 25m
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Greyhound US25h 20m022:30ChicagoDowntown Coach Station23:50San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 05/07/2025 22:30:00 to Coach Station, San Antonio, TX (USA) arriving at 06/07/2025 23:50:00. 50 Economy ticket for £186 per person are available. Travel duration is 25h 20m
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Greyhound US48h 40m022:30ChicagoDowntown Coach Station23:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 05/07/2025 22:30:00 to Pearl District, San Antonio, TX (USA) arriving at 07/07/2025 23:10:00. 50 Economy ticket for £186 per person are available. Travel duration is 48h 40m
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Greyhound US31h 35m010:00ChicagoUnion Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 05/07/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 06/07/2025 17:35:00. 50 Economy ticket for £187 per person are available. Travel duration is 31h 35m
Cheapest Buses Saturday
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Greyhound US48h 40m022:30ChicagoDowntown Coach Station23:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 06/07/2025 22:30:00 to Pearl District, San Antonio, TX (USA) arriving at 08/07/2025 23:10:00. 50 Economy ticket for £128 per person are available. Travel duration is 48h 40m
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Greyhound US25h 20m022:30ChicagoDowntown Coach Station23:50San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 06/07/2025 22:30:00 to Coach Station, San Antonio, TX (USA) arriving at 07/07/2025 23:50:00. 50 Economy ticket for £132 per person are available. Travel duration is 25h 20m
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Greyhound US49h 10m022:00ChicagoUnion Station23:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 06/07/2025 22:00:00 to Pearl District, San Antonio, TX (USA) arriving at 08/07/2025 23:10:00. 50 Economy ticket for £133 per person are available. Travel duration is 49h 10m
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FlixBus27h 10m009:45ChicagoDowntown Coach Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 06/07/2025 09:45:00 to Coach Station, San Antonio, TX (USA) arriving at 07/07/2025 12:55:00. 50 Economy ticket for £138 per person are available. Travel duration is 27h 10m
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FlixBus37h 25m009:45ChicagoDowntown Coach Station23:10San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 06/07/2025 09:45:00 to Pearl District, San Antonio, TX (USA) arriving at 07/07/2025 23:10:00. 50 Economy ticket for £140 per person are available. Travel duration is 37h 25m
Cheapest Buses Sunday
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Greyhound US25h 20m022:30ChicagoDowntown Coach Station23:50San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 08/07/2025 22:30:00 to Coach Station, San Antonio, TX (USA) arriving at 09/07/2025 23:50:00. 50 Economy ticket for £109 per person are available. Travel duration is 25h 20m
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FlixBus27h 10m009:45ChicagoDowntown Coach Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 08/07/2025 09:45:00 to Coach Station, San Antonio, TX (USA) arriving at 09/07/2025 12:55:00. 50 Economy ticket for £110 per person are available. Travel duration is 27h 10m
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FlixBus28h 45m000:15ChicagoDowntown Coach Station05:00San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 08/07/2025 00:15:00 to Coach Station, San Antonio, TX (USA) arriving at 09/07/2025 05:00:00. 50 Economy ticket for £112 per person are available. Travel duration is 28h 45m
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Greyhound US31h 35m010:00ChicagoUnion Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 08/07/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 09/07/2025 17:35:00. 50 Economy ticket for £117 per person are available. Travel duration is 31h 35m
Cheapest Buses Tuesday
What are the fastest trips from Chicago to San Antonio, TX?
You can get to San Antonio, TX from Chicago in just 25h 20m with a Bus from Greyhound US. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Greyhound US25h 20m022:30ChicagoDowntown Coach Station23:50San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 05/07/2025 22:30:00 to Coach Station, San Antonio, TX (USA) arriving at 06/07/2025 23:50:00. 50 Economy ticket for £186 per person are available. Travel duration is 25h 20m
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FlixBus28h 45m000:15ChicagoDowntown Coach Station05:00San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 05/07/2025 00:15:00 to Coach Station, San Antonio, TX (USA) arriving at 06/07/2025 05:00:00. 50 Economy ticket for £185 per person are available. Travel duration is 28h 45m
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Greyhound US31h 35m010:00ChicagoUnion Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 05/07/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 06/07/2025 17:35:00. 50 Economy ticket for £187 per person are available. Travel duration is 31h 35m
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FlixBus37h 25m009:45ChicagoDowntown Coach Station23:10San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 05/07/2025 09:45:00 to Pearl District, San Antonio, TX (USA) arriving at 06/07/2025 23:10:00. 50 Economy ticket for £186 per person are available. Travel duration is 37h 25m
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Greyhound US48h 40m022:30ChicagoDowntown Coach Station23:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 05/07/2025 22:30:00 to Pearl District, San Antonio, TX (USA) arriving at 07/07/2025 23:10:00. 50 Economy ticket for £186 per person are available. Travel duration is 48h 40m
Fastest Buses Saturday
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Greyhound US25h 20m022:30ChicagoDowntown Coach Station23:50San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 06/07/2025 22:30:00 to Coach Station, San Antonio, TX (USA) arriving at 07/07/2025 23:50:00. 50 Economy ticket for £132 per person are available. Travel duration is 25h 20m
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FlixBus27h 10m009:45ChicagoDowntown Coach Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 06/07/2025 09:45:00 to Coach Station, San Antonio, TX (USA) arriving at 07/07/2025 12:55:00. 50 Economy ticket for £138 per person are available. Travel duration is 27h 10m
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FlixBus37h 25m009:45ChicagoDowntown Coach Station23:10San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 06/07/2025 09:45:00 to Pearl District, San Antonio, TX (USA) arriving at 07/07/2025 23:10:00. 50 Economy ticket for £140 per person are available. Travel duration is 37h 25m
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Greyhound US48h 40m022:30ChicagoDowntown Coach Station23:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 06/07/2025 22:30:00 to Pearl District, San Antonio, TX (USA) arriving at 08/07/2025 23:10:00. 50 Economy ticket for £128 per person are available. Travel duration is 48h 40m
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Greyhound US49h 10m022:00ChicagoUnion Station23:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 06/07/2025 22:00:00 to Pearl District, San Antonio, TX (USA) arriving at 08/07/2025 23:10:00. 50 Economy ticket for £133 per person are available. Travel duration is 49h 10m
Fastest Buses Sunday
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Greyhound US25h 20m022:30ChicagoDowntown Coach Station23:50San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 08/07/2025 22:30:00 to Coach Station, San Antonio, TX (USA) arriving at 09/07/2025 23:50:00. 50 Economy ticket for £109 per person are available. Travel duration is 25h 20m
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FlixBus27h 10m009:45ChicagoDowntown Coach Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 08/07/2025 09:45:00 to Coach Station, San Antonio, TX (USA) arriving at 09/07/2025 12:55:00. 50 Economy ticket for £110 per person are available. Travel duration is 27h 10m
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FlixBus28h 45m000:15ChicagoDowntown Coach Station05:00San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 08/07/2025 00:15:00 to Coach Station, San Antonio, TX (USA) arriving at 09/07/2025 05:00:00. 50 Economy ticket for £112 per person are available. Travel duration is 28h 45m
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Greyhound US31h 35m010:00ChicagoUnion Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 08/07/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 09/07/2025 17:35:00. 50 Economy ticket for £117 per person are available. Travel duration is 31h 35m
Fastest Buses Tuesday
Here you will find all operators and timetables for a
Bus from Chicago to San Antonio, TX
What are the most popular stations in Chicago and San Antonio, TX?
In Chicago, you will usually depart from Union Station, 95th Red Line Station or California & 35th Street Coach Stop, while in San Antonio, TX you will be arriving at Coach Station, W. Southcross & Buffalo Bus Stop or La Cantera, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to San Antonio, TX from Chicago? With 4 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Chicago and San Antonio, TX, you can pay as low as £109 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from Greyhound US: you will get to San Antonio, TX in just 25h 20m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Chicago and San Antonio, TX are Greyhound US and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Chicago and San Antonio, TX is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Cicero, IL or to Olmos Park, TX, and look at flights from Chicago Midway Airport, and landing at San Antonio Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Chicago to San Antonio, TX?
The most popular companies between Chicago and San Antonio, TX, are Greyhound US and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
All you need to know when you travel from Chicago to San Antonio, TX
Check all information on comfort and services on all modes of transports from Chicago to San Antonio, TX. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Chicago to San Antonio, TX
How can I reach San Antonio, TX from Chicago?
Every day, there are on average 4 connections between Bus and Flight, with which you can get to San Antonio, TX from Chicago.
How far is San Antonio, TX from Chicago?
The distance between Chicago and San Antonio, TX is 1,692.8 km.
What is the most ecofriendly mode of transport between Chicago and San Antonio, TX?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 46 kgs of CO2, a train 59 kgs, a car 288 kgs, and a flight 416 kgs.
What is the cheapest mode of transport from Chicago to San Antonio, TX?
You can get to San Antonio, TX with just £109 by taking a Bus from Greyhound US.
What is the fastest way to get from Chicago to San Antonio, TX?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Antonio, TX in just 25h 20m with a Bus from Greyhound US.
More routes to Chicago and to San Antonio, TX
Looking for more options? Here you can see the most popular routes to Chicago and to San Antonio, TX. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Chicago
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- Guadalajara, JC to Chicago
- Houston to Chicago
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- Matamoros to Chicago
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- Mexico City to Chicago
- Monterrey, NL to Chicago
- New York to Chicago
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- Trips to San Antonio, TX
- Aguascalientes to San Antonio, TX
- Amarillo, TX to San Antonio, TX
- Beaumont, TX to San Antonio, TX
- Brownsville, TX to San Antonio, TX
- Ciudad Juárez to San Antonio, TX
- Dallas to San Antonio, TX
- El Paso, TX to San Antonio, TX
- Guadalajara, JC to San Antonio, TX
- McAllen, TX to San Antonio, TX
- Mexico City to San Antonio, TX
- Monterrey, NL to San Antonio, TX
- Orlando, FL to San Antonio, TX
- Phoenix, AZ to San Antonio, TX
- Reynosa to San Antonio, TX
- San Diego to San Antonio, TX
- San Luis Potosí to San Antonio, TX
- Santiago de Queretaro to San Antonio, TX
- Torreón, CO to San Antonio, TX
- Washington, DC to San Antonio, TX