What is the best way to travel from Chicago to San Antonio, TX?
Looking for a trip? Check and compare all the available Buses and Flights to San Antonio, TX from Chicago. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach San Antonio, TX from Chicago?
You can reach San Antonio, TX with just £88 by taking a Flight from Frontier Airlines, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
-
Frontier Airlines7h 11m007:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center14:11San Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 04/12/2025 07:00:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 04/12/2025 14:11:00. 50 Economy ticket for £88 per person are available. Travel duration is 7h 11m
-
Spirit Airlines15h 54m021:06Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center13:00San Antonio AirportSan Antonio Airport0EconomyA Flight from Spirit Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 04/12/2025 21:06:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 05/12/2025 13:00:00. 50 Economy ticket for £187 per person are available. Travel duration is 15h 54m
-
United Airlines3h 13m009:15Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:28San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 04/12/2025 09:15:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 04/12/2025 12:28:00. 50 Economy ticket for £296 per person are available. Travel duration is 3h 13m
-
Skyscanner3h 17m013:20Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center16:37San Antonio AirportSan Antonio Airport0EconomyA Flight from Skyscanner goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 04/12/2025 13:20:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 04/12/2025 16:37:00. 50 Economy ticket for £296 per person are available. Travel duration is 3h 17m
-
Alaska Airlines13h 58m010:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center23:58San Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 04/12/2025 10:00:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 04/12/2025 23:58:00. 50 Economy ticket for £420 per person are available. Travel duration is 13h 58m
-
FlixBus37h 15m010:10Chicago95th Red Line Station23:25San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 04/12/2025 10:10:00 to Pearl District, San Antonio, TX (USA) arriving at 05/12/2025 23:25:00. 50 Economy ticket for £133 per person are available. Travel duration is 37h 15m
-
FlixBus49h 45m019:25Chicago95th Red Line Station21:10San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 04/12/2025 19:25:00 to Pearl District, San Antonio, TX (USA) arriving at 06/12/2025 21:10:00. 50 Economy ticket for £134 per person are available. Travel duration is 49h 45m
-
Greyhound US48h 55m022:30Chicago95th Red Line Station23:25San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 04/12/2025 22:30:00 to Pearl District, San Antonio, TX (USA) arriving at 06/12/2025 23:25:00. 50 Economy ticket for £142 per person are available. Travel duration is 48h 55m
-
Tornado Bus Company23h 15m013:30ChicagoCalifornia & 35th Street Coach Stop12:45San Antonio, TXTornado Bus Company0BasicA Bus from Tornado Bus Company goes from California & 35th Street Coach Stop, Chicago (USA) at 04/12/2025 13:30:00 to Tornado Bus Company, San Antonio, TX (USA) arriving at 05/12/2025 12:45:00. 50 Basic ticket for £208 per person are available. Travel duration is 23h 15m
Cheapest Flights Thursday
Cheapest Buses Thursday
-
Greyhound US25h 20m022:30ChicagoDowntown Coach Station23:50San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 05/12/2025 22:30:00 to Coach Station, San Antonio, TX (USA) arriving at 06/12/2025 23:50:00. 50 Economy ticket for £145 per person are available. Travel duration is 25h 20m
-
FlixBus37h 40m009:45ChicagoDowntown Coach Station23:25San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 05/12/2025 09:45:00 to Pearl District, San Antonio, TX (USA) arriving at 06/12/2025 23:25:00. 50 Economy ticket for £146 per person are available. Travel duration is 37h 40m
-
Greyhound US46h 40m022:30ChicagoDowntown Coach Station21:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 05/12/2025 22:30:00 to Pearl District, San Antonio, TX (USA) arriving at 07/12/2025 21:10:00. 50 Economy ticket for £146 per person are available. Travel duration is 46h 40m
-
Greyhound US31h 35m010:00ChicagoUnion Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 05/12/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 06/12/2025 17:35:00. 50 Economy ticket for £146 per person are available. Travel duration is 31h 35m
-
FlixBus27h 10m009:45ChicagoDowntown Coach Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 05/12/2025 09:45:00 to Coach Station, San Antonio, TX (USA) arriving at 06/12/2025 12:55:00. 50 Economy ticket for £155 per person are available. Travel duration is 27h 10m
Cheapest Buses Friday
-
FlixBus37h 40m009:45ChicagoDowntown Coach Station23:25San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 06/12/2025 09:45:00 to Pearl District, San Antonio, TX (USA) arriving at 07/12/2025 23:25:00. 50 Economy ticket for £127 per person are available. Travel duration is 37h 40m
-
FlixBus27h 10m009:45ChicagoDowntown Coach Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 06/12/2025 09:45:00 to Coach Station, San Antonio, TX (USA) arriving at 07/12/2025 12:55:00. 50 Economy ticket for £128 per person are available. Travel duration is 27h 10m
-
Greyhound US25h 20m022:30ChicagoDowntown Coach Station23:50San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 06/12/2025 22:30:00 to Coach Station, San Antonio, TX (USA) arriving at 07/12/2025 23:50:00. 50 Economy ticket for £128 per person are available. Travel duration is 25h 20m
-
Greyhound US48h 55m022:30ChicagoDowntown Coach Station23:25San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 06/12/2025 22:30:00 to Pearl District, San Antonio, TX (USA) arriving at 08/12/2025 23:25:00. 50 Economy ticket for £128 per person are available. Travel duration is 48h 55m
-
Greyhound US31h 35m010:00ChicagoUnion Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 06/12/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 07/12/2025 17:35:00. 50 Economy ticket for £131 per person are available. Travel duration is 31h 35m
Cheapest Buses Saturday
-
FlixBus37h 40m009:45ChicagoDowntown Coach Station23:25San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 08/12/2025 09:45:00 to Pearl District, San Antonio, TX (USA) arriving at 09/12/2025 23:25:00. 50 Economy ticket for £123 per person are available. Travel duration is 37h 40m
-
FlixBus27h 10m009:45ChicagoDowntown Coach Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 08/12/2025 09:45:00 to Coach Station, San Antonio, TX (USA) arriving at 09/12/2025 12:55:00. 50 Economy ticket for £123 per person are available. Travel duration is 27h 10m
-
Greyhound US25h 25m022:30ChicagoDowntown Coach Station23:55San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 08/12/2025 22:30:00 to Coach Station, San Antonio, TX (USA) arriving at 09/12/2025 23:55:00. 50 Economy ticket for £123 per person are available. Travel duration is 25h 25m
-
Greyhound US31h 35m010:00ChicagoUnion Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 08/12/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 09/12/2025 17:35:00. 50 Economy ticket for £124 per person are available. Travel duration is 31h 35m
-
Greyhound US46h 40m022:30ChicagoDowntown Coach Station21:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 08/12/2025 22:30:00 to Pearl District, San Antonio, TX (USA) arriving at 10/12/2025 21:10:00. 50 Economy ticket for £126 per person are available. Travel duration is 46h 40m
Cheapest Buses Monday
-
Greyhound US49h 25m022:00ChicagoUnion Station23:25San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 10/12/2025 22:00:00 to Pearl District, San Antonio, TX (USA) arriving at 12/12/2025 23:25:00. 50 Economy ticket for £131 per person are available. Travel duration is 49h 25m
-
Greyhound US30h 45m006:10ChicagoDowntown Coach Station12:55San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 10/12/2025 06:10:00 to Coach Station, San Antonio, TX (USA) arriving at 11/12/2025 12:55:00. 50 Economy ticket for £134 per person are available. Travel duration is 30h 45m
-
Greyhound US31h 55m009:40ChicagoDowntown Coach Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 10/12/2025 09:40:00 to Coach Station, San Antonio, TX (USA) arriving at 11/12/2025 17:35:00. 50 Economy ticket for £135 per person are available. Travel duration is 31h 55m
-
Greyhound US31h 35m010:00ChicagoUnion Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 10/12/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 11/12/2025 17:35:00. 50 Economy ticket for £135 per person are available. Travel duration is 31h 35m
-
Greyhound US46h 40m022:30ChicagoDowntown Coach Station21:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 10/12/2025 22:30:00 to Pearl District, San Antonio, TX (USA) arriving at 12/12/2025 21:10:00. 50 Economy ticket for £137 per person are available. Travel duration is 46h 40m
Cheapest Buses Wednesday
What are the fastest trips from Chicago to San Antonio, TX?
You can get to San Antonio, TX from Chicago in just 3h 13m with a Flight from United Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
-
United Airlines3h 13m009:15Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:28San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 04/12/2025 09:15:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 04/12/2025 12:28:00. 50 Economy ticket for £296 per person are available. Travel duration is 3h 13m
-
Skyscanner3h 17m013:20Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center16:37San Antonio AirportSan Antonio Airport0EconomyA Flight from Skyscanner goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 04/12/2025 13:20:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 04/12/2025 16:37:00. 50 Economy ticket for £296 per person are available. Travel duration is 3h 17m
-
Frontier Airlines7h 11m007:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center14:11San Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 04/12/2025 07:00:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 04/12/2025 14:11:00. 50 Economy ticket for £88 per person are available. Travel duration is 7h 11m
-
Alaska Airlines13h 58m010:00Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center23:58San Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 04/12/2025 10:00:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 04/12/2025 23:58:00. 50 Economy ticket for £420 per person are available. Travel duration is 13h 58m
-
Spirit Airlines15h 54m021:06Chicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center13:00San Antonio AirportSan Antonio Airport0EconomyA Flight from Spirit Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 04/12/2025 21:06:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 05/12/2025 13:00:00. 50 Economy ticket for £187 per person are available. Travel duration is 15h 54m
-
Tornado Bus Company23h 15m013:30ChicagoCalifornia & 35th Street Coach Stop12:45San Antonio, TXTornado Bus Company0BasicA Bus from Tornado Bus Company goes from California & 35th Street Coach Stop, Chicago (USA) at 04/12/2025 13:30:00 to Tornado Bus Company, San Antonio, TX (USA) arriving at 05/12/2025 12:45:00. 50 Basic ticket for £208 per person are available. Travel duration is 23h 15m
-
FlixBus37h 15m010:10Chicago95th Red Line Station23:25San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 04/12/2025 10:10:00 to Pearl District, San Antonio, TX (USA) arriving at 05/12/2025 23:25:00. 50 Economy ticket for £133 per person are available. Travel duration is 37h 15m
-
Greyhound US48h 55m022:30Chicago95th Red Line Station23:25San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 04/12/2025 22:30:00 to Pearl District, San Antonio, TX (USA) arriving at 06/12/2025 23:25:00. 50 Economy ticket for £142 per person are available. Travel duration is 48h 55m
-
FlixBus49h 45m019:25Chicago95th Red Line Station21:10San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 04/12/2025 19:25:00 to Pearl District, San Antonio, TX (USA) arriving at 06/12/2025 21:10:00. 50 Economy ticket for £134 per person are available. Travel duration is 49h 45m
Fastest Flights Thursday
Fastest Buses Thursday
-
Greyhound US25h 20m022:30ChicagoDowntown Coach Station23:50San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 05/12/2025 22:30:00 to Coach Station, San Antonio, TX (USA) arriving at 06/12/2025 23:50:00. 50 Economy ticket for £145 per person are available. Travel duration is 25h 20m
-
FlixBus27h 10m009:45ChicagoDowntown Coach Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 05/12/2025 09:45:00 to Coach Station, San Antonio, TX (USA) arriving at 06/12/2025 12:55:00. 50 Economy ticket for £155 per person are available. Travel duration is 27h 10m
-
Greyhound US31h 35m010:00ChicagoUnion Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 05/12/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 06/12/2025 17:35:00. 50 Economy ticket for £146 per person are available. Travel duration is 31h 35m
-
FlixBus37h 40m009:45ChicagoDowntown Coach Station23:25San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 05/12/2025 09:45:00 to Pearl District, San Antonio, TX (USA) arriving at 06/12/2025 23:25:00. 50 Economy ticket for £146 per person are available. Travel duration is 37h 40m
-
Greyhound US46h 40m022:30ChicagoDowntown Coach Station21:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 05/12/2025 22:30:00 to Pearl District, San Antonio, TX (USA) arriving at 07/12/2025 21:10:00. 50 Economy ticket for £146 per person are available. Travel duration is 46h 40m
Fastest Buses Friday
-
Greyhound US25h 20m022:30ChicagoDowntown Coach Station23:50San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 06/12/2025 22:30:00 to Coach Station, San Antonio, TX (USA) arriving at 07/12/2025 23:50:00. 50 Economy ticket for £128 per person are available. Travel duration is 25h 20m
-
FlixBus27h 10m009:45ChicagoDowntown Coach Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 06/12/2025 09:45:00 to Coach Station, San Antonio, TX (USA) arriving at 07/12/2025 12:55:00. 50 Economy ticket for £128 per person are available. Travel duration is 27h 10m
-
Greyhound US31h 35m010:00ChicagoUnion Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 06/12/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 07/12/2025 17:35:00. 50 Economy ticket for £131 per person are available. Travel duration is 31h 35m
-
FlixBus37h 40m009:45ChicagoDowntown Coach Station23:25San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 06/12/2025 09:45:00 to Pearl District, San Antonio, TX (USA) arriving at 07/12/2025 23:25:00. 50 Economy ticket for £127 per person are available. Travel duration is 37h 40m
-
Greyhound US48h 55m022:30ChicagoDowntown Coach Station23:25San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 06/12/2025 22:30:00 to Pearl District, San Antonio, TX (USA) arriving at 08/12/2025 23:25:00. 50 Economy ticket for £128 per person are available. Travel duration is 48h 55m
Fastest Buses Saturday
-
Greyhound US25h 25m022:30ChicagoDowntown Coach Station23:55San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 08/12/2025 22:30:00 to Coach Station, San Antonio, TX (USA) arriving at 09/12/2025 23:55:00. 50 Economy ticket for £123 per person are available. Travel duration is 25h 25m
-
FlixBus27h 10m009:45ChicagoDowntown Coach Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 08/12/2025 09:45:00 to Coach Station, San Antonio, TX (USA) arriving at 09/12/2025 12:55:00. 50 Economy ticket for £123 per person are available. Travel duration is 27h 10m
-
Greyhound US31h 35m010:00ChicagoUnion Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 08/12/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 09/12/2025 17:35:00. 50 Economy ticket for £124 per person are available. Travel duration is 31h 35m
-
FlixBus37h 40m009:45ChicagoDowntown Coach Station23:25San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 08/12/2025 09:45:00 to Pearl District, San Antonio, TX (USA) arriving at 09/12/2025 23:25:00. 50 Economy ticket for £123 per person are available. Travel duration is 37h 40m
-
Greyhound US46h 40m022:30ChicagoDowntown Coach Station21:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 08/12/2025 22:30:00 to Pearl District, San Antonio, TX (USA) arriving at 10/12/2025 21:10:00. 50 Economy ticket for £126 per person are available. Travel duration is 46h 40m
Fastest Buses Monday
-
Greyhound US30h 45m006:10ChicagoDowntown Coach Station12:55San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 10/12/2025 06:10:00 to Coach Station, San Antonio, TX (USA) arriving at 11/12/2025 12:55:00. 50 Economy ticket for £134 per person are available. Travel duration is 30h 45m
-
Greyhound US31h 35m010:00ChicagoUnion Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 10/12/2025 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 11/12/2025 17:35:00. 50 Economy ticket for £135 per person are available. Travel duration is 31h 35m
-
Greyhound US31h 55m009:40ChicagoDowntown Coach Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 10/12/2025 09:40:00 to Coach Station, San Antonio, TX (USA) arriving at 11/12/2025 17:35:00. 50 Economy ticket for £135 per person are available. Travel duration is 31h 55m
-
Greyhound US46h 40m022:30ChicagoDowntown Coach Station21:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 10/12/2025 22:30:00 to Pearl District, San Antonio, TX (USA) arriving at 12/12/2025 21:10:00. 50 Economy ticket for £137 per person are available. Travel duration is 46h 40m
-
Greyhound US49h 25m022:00ChicagoUnion Station23:25San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 10/12/2025 22:00:00 to Pearl District, San Antonio, TX (USA) arriving at 12/12/2025 23:25:00. 50 Economy ticket for £131 per person are available. Travel duration is 49h 25m
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Chicago to San Antonio, TX
What are the most popular stations in Chicago and San Antonio, TX?
In Chicago, you will usually depart from California & 35th Street Coach Stop, Downtown Coach Station or 95th Red Line Station, while in San Antonio, TX you will be arriving at Tornado Bus Company, Coach Station or W. Southcross & Buffalo Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to San Antonio, TX from Chicago? With 6 connections between 3 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Chicago and San Antonio, TX, you can pay as low as £88 with a Flight from Frontier Airlines.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to San Antonio, TX in just 3h 13m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Chicago and San Antonio, TX are Greyhound US, FlixBus and Tornado Bus Company, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Chicago and San Antonio, TX is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Cicero, IL or to Olmos Park, TX, and look at flights from Chicago Midway Airport, and landing at San Antonio Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Chicago to San Antonio, TX?
The most popular companies between Chicago and San Antonio, TX, are Greyhound US, FlixBus and Tornado Bus Company. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US, FlixBus and Tornado Bus Company
Airlines: Frontier Airlines, Spirit Airlines, United Airlines and 2 more.
All you need to know when you travel from Chicago to San Antonio, TX
Check all information on comfort and services on all modes of transports from Chicago to San Antonio, TX. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Chicago to San Antonio, TX
How can I reach San Antonio, TX from Chicago?
Every day, there are on average 6 connections between Bus and Flight, with which you can get to San Antonio, TX from Chicago.
How far is San Antonio, TX from Chicago?
The distance between Chicago and San Antonio, TX is 1,692.8 km.
What is the most ecofriendly mode of transport between Chicago and San Antonio, TX?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 46 kgs of CO2, a train 59 kgs, a car 288 kgs, and a flight 416 kgs.
What is the cheapest mode of transport from Chicago to San Antonio, TX?
You can get to San Antonio, TX with just £88 by taking a Flight from Frontier Airlines.
What is the fastest way to get from Chicago to San Antonio, TX?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Antonio, TX in just 3h 13m with a Flight from United Airlines.
More routes to Chicago and to San Antonio, TX
Looking for more options? Here you can see the most popular routes to Chicago and to San Antonio, TX. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Chicago
- Aguascalientes to Chicago
- Atlanta, GA to Chicago
- Dallas to Chicago
- Durango, DG to Chicago
- El Paso, TX to Chicago
- Guadalajara, JC to Chicago
- Houston to Chicago
- Louisville, KY to Chicago
- McAllen, TX to Chicago
- Memphis to Chicago
- Mexico City to Chicago
- Monterrey, NL to Chicago
- Nashville to Chicago
- New York to Chicago
- Pearson Toronto Airport to Chicago
- Philadelphia, PA to Chicago
- Phoenix, AZ to Chicago
- San Antonio, TX to Chicago
- San Luis Potosí to Chicago
- Santiago de Queretaro to Chicago
- St. Louis, MO to Chicago
- Toronto, ON to Chicago
- Tulsa to Chicago
- Trips to San Antonio, TX
- Aguascalientes to San Antonio, TX
- Brownsville, TX to San Antonio, TX
- Ciudad Juárez to San Antonio, TX
- Dallas to San Antonio, TX
- Durango, DG to San Antonio, TX
- El Paso, TX to San Antonio, TX
- Guadalajara, JC to San Antonio, TX
- Houston to San Antonio, TX
- Las Vegas to San Antonio, TX
- McAllen, TX to San Antonio, TX
- Mexico City to San Antonio, TX
- Monterrey, NL to San Antonio, TX
- Orlando, FL to San Antonio, TX
- Phoenix, AZ to San Antonio, TX
- Reynosa to San Antonio, TX
- San Diego to San Antonio, TX
- San Luis Potosí to San Antonio, TX
- St. Louis, MO to San Antonio, TX
- Torreón, CO to San Antonio, TX
- Washington, DC to San Antonio, TX

