What is the best way to travel from Chicago to San Antonio, TX?
Looking for a trip? Check and compare all the available Buses and Flights to San Antonio, TX from Chicago. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach San Antonio, TX from Chicago?
You can reach San Antonio, TX with just £104 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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FlixBus27h 10m009:45ChicagoDowntown Coach Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 27/03/2026 09:45:00 to Coach Station, San Antonio, TX (USA) arriving at 28/03/2026 12:55:00. 50 Economy ticket for £104 per person are available. Travel duration is 27h 10m
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FlixBus35h 25m009:45ChicagoDowntown Coach Station21:10San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 27/03/2026 09:45:00 to Pearl District, San Antonio, TX (USA) arriving at 28/03/2026 21:10:00. 50 Economy ticket for £104 per person are available. Travel duration is 35h 25m
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Greyhound US25h 25m022:30ChicagoDowntown Coach Station23:55San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 27/03/2026 22:30:00 to Coach Station, San Antonio, TX (USA) arriving at 28/03/2026 23:55:00. 50 Economy ticket for £104 per person are available. Travel duration is 25h 25m
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Greyhound US31h 35m010:00ChicagoUnion Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 27/03/2026 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 28/03/2026 17:35:00. 50 Economy ticket for £104 per person are available. Travel duration is 31h 35m
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Greyhound US46h 20m022:50ChicagoDowntown Coach Station21:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 27/03/2026 22:50:00 to Pearl District, San Antonio, TX (USA) arriving at 29/03/2026 21:10:00. 50 Economy ticket for £107 per person are available. Travel duration is 46h 20m
Cheapest Buses Friday
What are the fastest trips from Chicago to San Antonio, TX?
You can get to San Antonio, TX from Chicago in just 25h 25m with a Bus from Greyhound US. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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Greyhound US25h 25m022:30ChicagoDowntown Coach Station23:55San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 27/03/2026 22:30:00 to Coach Station, San Antonio, TX (USA) arriving at 28/03/2026 23:55:00. 50 Economy ticket for £104 per person are available. Travel duration is 25h 25m
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FlixBus27h 10m009:45ChicagoDowntown Coach Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 27/03/2026 09:45:00 to Coach Station, San Antonio, TX (USA) arriving at 28/03/2026 12:55:00. 50 Economy ticket for £104 per person are available. Travel duration is 27h 10m
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Greyhound US31h 35m010:00ChicagoUnion Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 27/03/2026 10:00:00 to Coach Station, San Antonio, TX (USA) arriving at 28/03/2026 17:35:00. 50 Economy ticket for £104 per person are available. Travel duration is 31h 35m
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FlixBus35h 25m009:45ChicagoDowntown Coach Station21:10San Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Coach Station, Chicago (USA) at 27/03/2026 09:45:00 to Pearl District, San Antonio, TX (USA) arriving at 28/03/2026 21:10:00. 50 Economy ticket for £104 per person are available. Travel duration is 35h 25m
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Greyhound US46h 20m022:50ChicagoDowntown Coach Station21:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Coach Station, Chicago (USA) at 27/03/2026 22:50:00 to Pearl District, San Antonio, TX (USA) arriving at 29/03/2026 21:10:00. 50 Economy ticket for £107 per person are available. Travel duration is 46h 20m
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from Chicago to San Antonio, TX
What are the most popular stations in Chicago and San Antonio, TX?
In Chicago, you will usually depart from Downtown Coach Station, 95th Red Line Station or California & 35th Street Coach Stop, while in San Antonio, TX you will be arriving at Tornado Bus Company, Coach Station or W. Southcross & Buffalo Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to San Antonio, TX from Chicago? With 5 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Chicago and San Antonio, TX, you can pay as low as £104 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from Greyhound US: you will get to San Antonio, TX in just 25h 25m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Chicago and San Antonio, TX are Greyhound US and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Chicago and San Antonio, TX is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Cicero, IL or to Olmos Park, TX, and look at flights from Chicago Midway Airport, and landing at San Antonio Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Chicago to San Antonio, TX?
The most popular companies between Chicago and San Antonio, TX, are Greyhound US and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
All you need to know when you travel from Chicago to San Antonio, TX
Check all information on comfort and services on all modes of transports from Chicago to San Antonio, TX. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Chicago to San Antonio, TX
How can I reach San Antonio, TX from Chicago?
Every day, there are on average 5 connections between Flight and Bus, with which you can get to San Antonio, TX from Chicago.
How far is San Antonio, TX from Chicago?
The distance between Chicago and San Antonio, TX is 1,692.8 km.
What is the most ecofriendly mode of transport between Chicago and San Antonio, TX?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 46 kgs of CO2, a train 59 kgs, a car 288 kgs, and a flight 416 kgs.
What is the cheapest mode of transport from Chicago to San Antonio, TX?
You can get to San Antonio, TX with just £104 by taking a Bus from FlixBus.
What is the fastest way to get from Chicago to San Antonio, TX?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Antonio, TX in just 25h 25m with a Bus from Greyhound US.
More routes to Chicago and to San Antonio, TX
Looking for more options? Here you can see the most popular routes to Chicago and to San Antonio, TX. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Chicago
- Aguascalientes to Chicago
- Atlanta, GA to Chicago
- Buffalo, NY to Chicago
- Cincinnati to Chicago
- Dallas to Chicago
- Durango, DG to Chicago
- El Paso, TX to Chicago
- Houston to Chicago
- Los Angeles to Chicago
- Louisville, KY to Chicago
- Memphis to Chicago
- Mexico City to Chicago
- Monterrey, NL to Chicago
- Nashville to Chicago
- New York to Chicago
- Pearson Toronto Airport to Chicago
- Phoenix, AZ to Chicago
- Pittsburgh to Chicago
- San Antonio, TX to Chicago
- St. Louis, MO to Chicago
- Toronto, ON to Chicago
- Tulsa to Chicago
- Trips to San Antonio, TX
- Aguascalientes to San Antonio, TX
- Atlanta, GA to San Antonio, TX
- Beaumont, TX to San Antonio, TX
- Brownsville, TX to San Antonio, TX
- Ciudad Juárez to San Antonio, TX
- Dallas to San Antonio, TX
- El Paso, TX to San Antonio, TX
- Fort Worth to San Antonio, TX
- Houston to San Antonio, TX
- Los Angeles to San Antonio, TX
- McAllen, TX to San Antonio, TX
- Mexico City to San Antonio, TX
- Monterrey, NL to San Antonio, TX
- New Orleans, LA to San Antonio, TX
- Orlando, FL to San Antonio, TX
- Phoenix, AZ to San Antonio, TX
- Saltillo to San Antonio, TX
- San Luis Potosí to San Antonio, TX
- Santiago de Queretaro to San Antonio, TX
- Zacatecas, ZS to San Antonio, TX
