What is the best way to travel from St. Louis, MO to San Antonio, TX?
Looking for a trip? Check and compare all the available Buses and Flights to San Antonio, TX from St. Louis, MO. Look at different modes of transportation, search for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach San Antonio, TX from St. Louis, MO?
You can reach San Antonio, TX with just £70 by taking a Bus from FlixBus, but there are many more cheap offers: we have selected the best ones for you for the next few days here.
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Greyhound US28h 40m016:30St. Louis, MOGateway Station21:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 26/06/2026 16:30:00 to Pearl District, San Antonio, TX (USA) arriving at 27/06/2026 21:10:00. 50 Economy ticket for £73 per person are available. Travel duration is 28h 40m
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Greyhound US22h 35m001:20St. Louis, MOGateway Station23:55San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 26/06/2026 01:20:00 to Coach Station, San Antonio, TX (USA) arriving at 26/06/2026 23:55:00. 50 Economy ticket for £74 per person are available. Travel duration is 22h 35m
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Greyhound US25h 5m016:30St. Louis, MOGateway Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 26/06/2026 16:30:00 to Coach Station, San Antonio, TX (USA) arriving at 27/06/2026 17:35:00. 50 Economy ticket for £74 per person are available. Travel duration is 25h 5m
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FlixBus20h 55m016:00St. Louis, MOGateway Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 26/06/2026 16:00:00 to Coach Station, San Antonio, TX (USA) arriving at 27/06/2026 12:55:00. 50 Economy ticket for £74 per person are available. Travel duration is 20h 55m
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United Airlines9h 20m006:01St. Louis Lambert AirportSt. Louis Lambert Airport15:21San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 06:01:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 26/06/2026 15:21:00. 50 Economy ticket for £210 per person are available. Travel duration is 9h 20m
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United Airlines4h 12m018:30St. Louis Lambert AirportSt. Louis Lambert Airport22:42San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 18:30:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 26/06/2026 22:42:00. 50 Economy ticket for £230 per person are available. Travel duration is 4h 12m
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United Airlines6h 14m006:00St. Louis Lambert AirportSt. Louis Lambert Airport12:14San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 06:00:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 26/06/2026 12:14:00. 50 Economy ticket for £239 per person are available. Travel duration is 6h 14m
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Frontier Airlines23h 18m019:38St. Louis Lambert AirportSt. Louis Lambert Airport18:56San Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 19:38:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 27/06/2026 18:56:00. 50 Economy ticket for £250 per person are available. Travel duration is 23h 18m
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Frontier Airlines23h 20m016:17St. Louis Lambert AirportSt. Louis Lambert Airport15:37San Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 16:17:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 27/06/2026 15:37:00. 50 Economy ticket for £284 per person are available. Travel duration is 23h 20m
Cheapest Buses Friday
Cheapest Flights Friday
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Greyhound US22h 35m001:20St. Louis, MOGateway Station23:55San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 01:20:00 to Coach Station, San Antonio, TX (USA) arriving at 27/06/2026 23:55:00. 50 Economy ticket for £78 per person are available. Travel duration is 22h 35m
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Greyhound US25h 40m016:30St. Louis, MOGateway Station18:10San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 16:30:00 to Coach Station, San Antonio, TX (USA) arriving at 28/06/2026 18:10:00. 50 Economy ticket for £78 per person are available. Travel duration is 25h 40m
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Greyhound US25h 30m023:45St. Louis, MOGateway Station01:15San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 23:45:00 to Coach Station, San Antonio, TX (USA) arriving at 29/06/2026 01:15:00. 50 Economy ticket for £78 per person are available. Travel duration is 25h 30m
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FlixBus20h 55m016:00St. Louis, MOGateway Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 16:00:00 to Coach Station, San Antonio, TX (USA) arriving at 28/06/2026 12:55:00. 50 Economy ticket for £78 per person are available. Travel duration is 20h 55m
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United Airlines6h 14m006:00St. Louis Lambert AirportSt. Louis Lambert Airport12:14San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 06:00:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 27/06/2026 12:14:00. 50 Economy ticket for £179 per person are available. Travel duration is 6h 14m
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United Airlines5h 24m017:33St. Louis Lambert AirportSt. Louis Lambert Airport22:57San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 17:33:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 27/06/2026 22:57:00. 50 Economy ticket for £179 per person are available. Travel duration is 5h 24m
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Frontier Airlines23h 18m019:38St. Louis Lambert AirportSt. Louis Lambert Airport18:56San Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 19:38:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 28/06/2026 18:56:00. 50 Economy ticket for £219 per person are available. Travel duration is 23h 18m
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Skyscanner4h 32m006:14St. Louis Lambert AirportSt. Louis Lambert Airport10:46San Antonio AirportSan Antonio Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 06:14:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 27/06/2026 10:46:00. 50 Economy ticket for £383 per person are available. Travel duration is 4h 32m
Cheapest Buses Saturday
Cheapest Flights Saturday
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FlixBus20h 55m016:00St. Louis, MOGateway Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 16:00:00 to Coach Station, San Antonio, TX (USA) arriving at 29/06/2026 12:55:00. 50 Economy ticket for £70 per person are available. Travel duration is 20h 55m
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Greyhound US22h 35m001:20St. Louis, MOGateway Station23:55San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 01:20:00 to Coach Station, San Antonio, TX (USA) arriving at 28/06/2026 23:55:00. 50 Economy ticket for £71 per person are available. Travel duration is 22h 35m
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Greyhound US25h 40m016:30St. Louis, MOGateway Station18:10San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 16:30:00 to Coach Station, San Antonio, TX (USA) arriving at 29/06/2026 18:10:00. 50 Economy ticket for £71 per person are available. Travel duration is 25h 40m
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Greyhound US25h 30m023:45St. Louis, MOGateway Station01:15San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 23:45:00 to Coach Station, San Antonio, TX (USA) arriving at 30/06/2026 01:15:00. 50 Economy ticket for £71 per person are available. Travel duration is 25h 30m
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Frontier Airlines23h 18m019:38St. Louis Lambert AirportSt. Louis Lambert Airport18:56San Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 19:38:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 29/06/2026 18:56:00. 50 Economy ticket for £243 per person are available. Travel duration is 23h 18m
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Frontier Airlines29h 15m014:56St. Louis Lambert AirportSt. Louis Lambert Airport20:11San Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 14:56:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 29/06/2026 20:11:00. 50 Economy ticket for £272 per person are available. Travel duration is 29h 15m
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United Airlines7h 33m005:10St. Louis Lambert AirportSt. Louis Lambert Airport12:43San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 05:10:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 28/06/2026 12:43:00. 50 Economy ticket for £397 per person are available. Travel duration is 7h 33m
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Alaska Airlines22h 58m006:02St. Louis Lambert AirportSt. Louis Lambert Airport05:00San Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 06:02:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 29/06/2026 05:00:00. 50 Economy ticket for £406 per person are available. Travel duration is 22h 58m
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United Airlines5h 0m014:57St. Louis Lambert AirportSt. Louis Lambert Airport19:57San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 14:57:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 28/06/2026 19:57:00. 50 Economy ticket for £443 per person are available. Travel duration is 5h 0m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Greyhound US25h 30m023:45St. Louis, MOGateway Station01:15San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 29/06/2026 23:45:00 to Coach Station, San Antonio, TX (USA) arriving at 01/07/2026 01:15:00. 50 Economy ticket for £72 per person are available. Travel duration is 25h 30m
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Greyhound US25h 40m016:30St. Louis, MOGateway Station18:10San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 29/06/2026 16:30:00 to Coach Station, San Antonio, TX (USA) arriving at 30/06/2026 18:10:00. 50 Economy ticket for £73 per person are available. Travel duration is 25h 40m
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FlixBus20h 55m016:00St. Louis, MOGateway Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 29/06/2026 16:00:00 to Coach Station, San Antonio, TX (USA) arriving at 30/06/2026 12:55:00. 50 Economy ticket for £73 per person are available. Travel duration is 20h 55m
Cheapest Buses Monday
What are the fastest trips from St. Louis, MO to San Antonio, TX?
You can get to San Antonio, TX from St. Louis, MO in just 4h 12m with a Flight from United Airlines. But this is just one option, click on any of the offers below to compare it with the other available modes of transportations.
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United Airlines4h 12m018:30St. Louis Lambert AirportSt. Louis Lambert Airport22:42San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 18:30:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 26/06/2026 22:42:00. 50 Economy ticket for £230 per person are available. Travel duration is 4h 12m
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United Airlines6h 14m006:00St. Louis Lambert AirportSt. Louis Lambert Airport12:14San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 06:00:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 26/06/2026 12:14:00. 50 Economy ticket for £239 per person are available. Travel duration is 6h 14m
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United Airlines9h 20m006:01St. Louis Lambert AirportSt. Louis Lambert Airport15:21San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 06:01:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 26/06/2026 15:21:00. 50 Economy ticket for £210 per person are available. Travel duration is 9h 20m
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Frontier Airlines23h 18m019:38St. Louis Lambert AirportSt. Louis Lambert Airport18:56San Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 19:38:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 27/06/2026 18:56:00. 50 Economy ticket for £250 per person are available. Travel duration is 23h 18m
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Frontier Airlines23h 20m016:17St. Louis Lambert AirportSt. Louis Lambert Airport15:37San Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 26/06/2026 16:17:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 27/06/2026 15:37:00. 50 Economy ticket for £284 per person are available. Travel duration is 23h 20m
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FlixBus20h 55m016:00St. Louis, MOGateway Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 26/06/2026 16:00:00 to Coach Station, San Antonio, TX (USA) arriving at 27/06/2026 12:55:00. 50 Economy ticket for £74 per person are available. Travel duration is 20h 55m
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Greyhound US22h 35m001:20St. Louis, MOGateway Station23:55San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 26/06/2026 01:20:00 to Coach Station, San Antonio, TX (USA) arriving at 26/06/2026 23:55:00. 50 Economy ticket for £74 per person are available. Travel duration is 22h 35m
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Greyhound US25h 5m016:30St. Louis, MOGateway Station17:35San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 26/06/2026 16:30:00 to Coach Station, San Antonio, TX (USA) arriving at 27/06/2026 17:35:00. 50 Economy ticket for £74 per person are available. Travel duration is 25h 5m
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Greyhound US28h 40m016:30St. Louis, MOGateway Station21:10San Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 26/06/2026 16:30:00 to Pearl District, San Antonio, TX (USA) arriving at 27/06/2026 21:10:00. 50 Economy ticket for £73 per person are available. Travel duration is 28h 40m
Fastest Flights Friday
Fastest Buses Friday
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Skyscanner4h 32m006:14St. Louis Lambert AirportSt. Louis Lambert Airport10:46San Antonio AirportSan Antonio Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 06:14:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 27/06/2026 10:46:00. 50 Economy ticket for £383 per person are available. Travel duration is 4h 32m
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United Airlines5h 24m017:33St. Louis Lambert AirportSt. Louis Lambert Airport22:57San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 17:33:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 27/06/2026 22:57:00. 50 Economy ticket for £179 per person are available. Travel duration is 5h 24m
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United Airlines6h 14m006:00St. Louis Lambert AirportSt. Louis Lambert Airport12:14San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 06:00:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 27/06/2026 12:14:00. 50 Economy ticket for £179 per person are available. Travel duration is 6h 14m
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Frontier Airlines23h 18m019:38St. Louis Lambert AirportSt. Louis Lambert Airport18:56San Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 27/06/2026 19:38:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 28/06/2026 18:56:00. 50 Economy ticket for £219 per person are available. Travel duration is 23h 18m
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FlixBus20h 55m016:00St. Louis, MOGateway Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 16:00:00 to Coach Station, San Antonio, TX (USA) arriving at 28/06/2026 12:55:00. 50 Economy ticket for £78 per person are available. Travel duration is 20h 55m
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Greyhound US22h 35m001:20St. Louis, MOGateway Station23:55San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 01:20:00 to Coach Station, San Antonio, TX (USA) arriving at 27/06/2026 23:55:00. 50 Economy ticket for £78 per person are available. Travel duration is 22h 35m
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Greyhound US25h 30m023:45St. Louis, MOGateway Station01:15San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 23:45:00 to Coach Station, San Antonio, TX (USA) arriving at 29/06/2026 01:15:00. 50 Economy ticket for £78 per person are available. Travel duration is 25h 30m
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Greyhound US25h 40m016:30St. Louis, MOGateway Station18:10San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 27/06/2026 16:30:00 to Coach Station, San Antonio, TX (USA) arriving at 28/06/2026 18:10:00. 50 Economy ticket for £78 per person are available. Travel duration is 25h 40m
Fastest Flights Saturday
Fastest Buses Saturday
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United Airlines5h 0m014:57St. Louis Lambert AirportSt. Louis Lambert Airport19:57San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 14:57:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 28/06/2026 19:57:00. 50 Economy ticket for £443 per person are available. Travel duration is 5h 0m
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United Airlines7h 33m005:10St. Louis Lambert AirportSt. Louis Lambert Airport12:43San Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 05:10:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 28/06/2026 12:43:00. 50 Economy ticket for £397 per person are available. Travel duration is 7h 33m
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Alaska Airlines22h 58m006:02St. Louis Lambert AirportSt. Louis Lambert Airport05:00San Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 06:02:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 29/06/2026 05:00:00. 50 Economy ticket for £406 per person are available. Travel duration is 22h 58m
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Frontier Airlines23h 18m019:38St. Louis Lambert AirportSt. Louis Lambert Airport18:56San Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 19:38:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 29/06/2026 18:56:00. 50 Economy ticket for £243 per person are available. Travel duration is 23h 18m
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Frontier Airlines29h 15m014:56St. Louis Lambert AirportSt. Louis Lambert Airport20:11San Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 28/06/2026 14:56:00 to San Antonio Airport, San Antonio Airport (USA) arriving at 29/06/2026 20:11:00. 50 Economy ticket for £272 per person are available. Travel duration is 29h 15m
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FlixBus20h 55m016:00St. Louis, MOGateway Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 16:00:00 to Coach Station, San Antonio, TX (USA) arriving at 29/06/2026 12:55:00. 50 Economy ticket for £70 per person are available. Travel duration is 20h 55m
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Greyhound US22h 35m001:20St. Louis, MOGateway Station23:55San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 01:20:00 to Coach Station, San Antonio, TX (USA) arriving at 28/06/2026 23:55:00. 50 Economy ticket for £71 per person are available. Travel duration is 22h 35m
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Greyhound US25h 30m023:45St. Louis, MOGateway Station01:15San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 23:45:00 to Coach Station, San Antonio, TX (USA) arriving at 30/06/2026 01:15:00. 50 Economy ticket for £71 per person are available. Travel duration is 25h 30m
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Greyhound US25h 40m016:30St. Louis, MOGateway Station18:10San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 28/06/2026 16:30:00 to Coach Station, San Antonio, TX (USA) arriving at 29/06/2026 18:10:00. 50 Economy ticket for £71 per person are available. Travel duration is 25h 40m
Fastest Flights Sunday
Fastest Buses Sunday
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FlixBus20h 55m016:00St. Louis, MOGateway Station12:55San Antonio, TXCoach Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 29/06/2026 16:00:00 to Coach Station, San Antonio, TX (USA) arriving at 30/06/2026 12:55:00. 50 Economy ticket for £73 per person are available. Travel duration is 20h 55m
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Greyhound US25h 30m023:45St. Louis, MOGateway Station01:15San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 29/06/2026 23:45:00 to Coach Station, San Antonio, TX (USA) arriving at 01/07/2026 01:15:00. 50 Economy ticket for £72 per person are available. Travel duration is 25h 30m
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Greyhound US25h 40m016:30St. Louis, MOGateway Station18:10San Antonio, TXCoach Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 29/06/2026 16:30:00 to Coach Station, San Antonio, TX (USA) arriving at 30/06/2026 18:10:00. 50 Economy ticket for £73 per person are available. Travel duration is 25h 40m
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from St. Louis, MO to San Antonio, TX
What are the most popular stations in St. Louis, MO and San Antonio, TX?
In St. Louis, MO, you will usually depart from Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, while in San Antonio, TX you will be arriving at Tornado Bus Company, Coach Station or W. Southcross & Buffalo Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to San Antonio, TX from St. Louis, MO? With 8 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between St. Louis, MO and San Antonio, TX, you can pay as low as £70 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to San Antonio, TX in just 4h 12m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting St. Louis, MO and San Antonio, TX are Greyhound US, United Airlines and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in St. Louis, MO and San Antonio, TX is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Sauget, IL or to Olmos Park, TX, and look at flights from St. Louis Lambert Airport, and landing at San Antonio Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from St. Louis, MO to San Antonio, TX?
The most popular companies between St. Louis, MO and San Antonio, TX, are Greyhound US, United Airlines and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: United Airlines, Frontier Airlines, Skyscanner and 1 more.
All you need to know when you travel from St. Louis, MO to San Antonio, TX
Check all information on comfort and services on all modes of transports from St. Louis, MO to San Antonio, TX. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from St. Louis, MO to San Antonio, TX
How can I reach San Antonio, TX from St. Louis, MO?
Every day, there are on average 8 connections between Flight and Bus, with which you can get to San Antonio, TX from St. Louis, MO.
How far is San Antonio, TX from St. Louis, MO?
The distance between St. Louis, MO and San Antonio, TX is 1,274.6 km.
What is the most ecofriendly mode of transport between St. Louis, MO and San Antonio, TX?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 34 kgs of CO2, a train 45 kgs, a car 217 kgs, and a flight 314 kgs.
What is the cheapest mode of transport from St. Louis, MO to San Antonio, TX?
You can get to San Antonio, TX with just £70 by taking a Bus from FlixBus.
What is the fastest way to get from St. Louis, MO to San Antonio, TX?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Antonio, TX in just 4h 12m with a Flight from United Airlines.
More routes to St. Louis, MO and to San Antonio, TX
Looking for more options? Here you can see the most popular routes to St. Louis, MO and to San Antonio, TX. Simply click on a connection, and you’ll find all the details about the route!
- Trips to St. Louis, MO
- Atlanta, GA to St. Louis, MO
- Dallas to St. Louis, MO
- Houston to St. Louis, MO
- Mexico City to St. Louis, MO
- Monterrey, NL to St. Louis, MO
- New York to St. Louis, MO
- Trips to San Antonio, TX
- Aguascalientes to San Antonio, TX
- Atlanta, GA to San Antonio, TX
- Brownsville, TX to San Antonio, TX
- Chicago to San Antonio, TX
- Durango, DG to San Antonio, TX
- El Paso, TX to San Antonio, TX
- Fort Worth to San Antonio, TX
- Guadalajara, JC to San Antonio, TX
- Harlingen, TX to San Antonio, TX
- Houston to San Antonio, TX
- Los Angeles to San Antonio, TX
- Memphis to San Antonio, TX
- Mexico City to San Antonio, TX
- Monterrey, NL to San Antonio, TX
- Phoenix, AZ to San Antonio, TX
- Saltillo to San Antonio, TX
- San Luis Potosí to San Antonio, TX
- Torreón, CO to San Antonio, TX
- Zacatecas, ZS to San Antonio, TX
